Hub : Genes

LOC723809

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Glioblastoma Multiforme 0.185 0.086 0.0078 0.04 0.014 0.050 NA -0.010 0.02300 0.1200 0.0120 NA 0.91000
2 TCGA Ovarian Serous Cystadenocarcinoma 0.053 0.027 0.0065 0.05 0.039 0.034 NA 0.048 0.00027 0.0012 0.0023 NA 0.00034

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 3.3 5.2 10.1 0.5 -3.2
Bipolar Disorder or Schizophrenia 6.4 15.7 30.2 -1.1 -5.5
Depressed Affect (Nagel 2018) 1.0 2.0 3.7 0.6 -1.9
Depression (Nagel 2018) 0.9 1.3 1.7 -1.0 -1.3
Intelligence (Savage-Jansen 2018) 2.5 7.6 10.8 2.1 3.3
Neuroticism (Nagel 2018) 0.4 0.9 1.7 -0.3 -1.3
Schizophrenia (2018) 5.7 11.8 20.2 -1.8 -4.5
Schizophrenia vs Biploar Disorder 2.5 3.3 6.4 -2.5 -0.5
Worry (Nagel 2018) 0.2 0.4 0.8 -0.9 0.3
Alzheimer’s Disease (in mother) 1.0 1.1 1.4 -0.9 1.2
Alzheimer’s Disease (in father) 0.1 0.1 0.2 0.2 0.4
Alzheimer’s Disease (including proxy) 0.6 0.9 1.8 -1.3 0.3
Crohns Disease (2017) 0.0 0.0 0.0 0.1 0.2
Irritable Bowel Disease (IBD) 0.2 0.4 0.6 -0.5 0.8
Ulcerative Colitis (UC) 0.4 0.8 0.8 -0.9 0.9
Major Depression (MDD) 0.4 0.5 0.8 -0.5 -0.9
Reaction Time 1.4 2.7 5.4 0.1 -2.3
Verbal and Numeric Reasoning (VNR) 3.3 7.9 13.9 1.4 3.7
Breast Cancer 0.3 0.6 1.3 -1.1 -0.0
Ovarian Cancer 0.6 0.7 1.4 -1.2 0.3
Prostate Cancer 2.7 3.7 5.7 1.3 -2.4
Age at First Birth 0.1 0.1 0.2 -0.4 -0.1
Bipolar Disorder (2011) 0.2 0.2 0.3 0.3 -0.5
Body Mass Index (BMI) (2010) 1.6 2.1 3.9 -2.0 -0.6
Coronary Artery Disease (CAD) 1.4 1.7 3.1 -0.5 1.8
Crohns Disease (2012) 0.0 0.1 0.2 0.0 0.4
Mean Putamen Volume 0.5 0.6 0.7 0.8 -0.7
Fasting Glucose 0.8 1.0 1.1 -1.1 -0.9
HbA1C 0.5 0.6 1.1 -1.1 0.2
HDL Cholesterol 0.6 1.0 2.0 0.2 1.4
LDL Cholesterol 0.1 0.1 0.2 -0.0 0.4
Lupus 2.0 3.0 4.4 -2.1 1.3
Neuroticism (2016) 0.0 0.0 0.0 -0.1 -0.1
Primary Biliary Cirrhosis 0.3 0.5 0.7 0.5 0.8
Rheumatoid Arthritis 0.1 0.1 0.2 -0.1 -0.4
Schizophrenia (2014) 5.4 12.0 17.5 -2.5 -4.2
Triglycerides 1.6 2.7 3.3 -1.4 -1.8
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.0 0.1 -0.2
Ulcerative Colitis 0.1 0.1 0.1 -0.2 0.4
Blood Eosinophil Count 0.2 1.4 2.8 -0.2 -1.7
Blood Platelet Count 0.0 0.4 0.6 0.8 0.4
Blood Red Count 0.1 1.3 2.6 -1.6 0.1
Blood White Count 0.3 2.6 4.9 -2.2 -0.5
Heel T-Score 0.4 2.8 5.1 -0.7 2.3
BMI 1.5 8.7 17.3 -0.2 -4.2
Height 0.5 9.9 16.0 -1.9 -4.0
Waist Hip Ratio (WHR) 4.6 20.7 41.1 0.6 -6.4
Systolic Blood Pressure 0.6 2.9 5.6 -0.4 -2.4
Smoking Status 0.1 0.2 0.4 -0.0 -0.7
Allergy or Eczema 0.3 0.9 1.7 0.3 1.3
Cardiovascular Disease 1.5 5.1 9.0 -1.1 -3.0
Hypothyroidism (self reported) 0.0 0.1 0.2 0.4 0.1
Respiratory disease 0.4 0.8 1.2 -1.1 -0.6
Type 2 Diabetes (T2D) (2018) 1.5 2.8 5.5 0.0 -2.3
Lung FEV1/FVC ratio 0.1 0.4 0.6 -0.2 0.8
Lung FVC 3.8 19.2 37.7 0.9 6.1
Neuroticism 0.3 0.8 1.0 -0.8 -1.0
Chronotype (morning person) 0.1 0.3 0.4 0.6 -0.5
Hair Pigment 0.1 2.9 5.8 0.1 -2.4
Tanning 0.3 3.6 7.2 0.0 2.7
Hand grip strength (left) 1.4 3.6 6.3 -2.5 0.9
Number of treatments/medications taken 0.1 0.2 0.2 0.5 -0.4
Average weekly spirits intake 2.6 3.3 5.3 1.1 -2.3
Sensitivity / hurt feelings 1.0 1.8 3.1 -0.6 -1.8
Frequency of depressed mood in last 2 weeks 0.9 1.3 2.5 -0.3 -1.6
Hearing difficulty/problems: Yes 1.5 2.3 4.3 0.5 -2.1
Relative age of first facial hair 2.5 5.1 7.8 -2.8 1.6
Other serious medical condition/disability diagnosed by doctor 2.0 2.5 5.0 -0.2 -2.2
Ever used hormone-replacement therapy (HRT) 1.5 1.9 3.3 -1.8 0.7
Ever had hysterectomy (womb removed) 0.4 0.4 0.5 -0.6 -0.7
Systolic blood pressure, automated reading 0.4 1.2 2.4 -0.1 -1.6
Eye problems/disorders: Diabetes related eye disease 2.8 3.0 6.1 -0.1 -2.5
Angina 0.1 0.1 0.2 -0.4 -0.1
Medication for hormone replacement therapy 1.6 1.8 2.9 -1.7 0.8
Vitamin and mineral supplements 0.1 0.2 0.3 -0.6 -0.2
Supplements: Zinc 0.9 1.0 1.8 -0.4 -1.3
Medication: Co-codamol 0.2 0.2 0.3 -0.5 -0.3
Medication: Metformin 1.1 1.6 2.4 0.9 -1.6
Diabetes (father) 1.3 1.6 2.5 -1.6 -0.9
Diabetes (mother) 0.6 0.8 1.1 0.6 1.1
Severe depression (siblings) 4.1 4.6 5.8 2.4 -1.9
Pack years adult smoking proportion 0.8 1.2 2.5 -1.6 -0.1
Impedance of leg (right) 0.1 0.4 0.8 -0.9 0.1
Leg fat-free mass (left) 0.7 3.7 7.3 0.3 -2.7
Trunk fat percentage 1.5 6.1 12.3 0.1 -3.5
Hand grip strength (right) 1.5 3.9 5.2 -1.7 2.3
Townsend deprivation index at recruitment 1.4 2.0 4.0 -2.0 0.2
Current tobacco smoking 0.3 0.5 0.9 0.2 -0.9
Average weekly fortified wine intake 0.5 0.5 0.5 0.7 0.7
Maternal smoking around birth 0.7 1.0 1.7 -1.3 -0.4
Fed-up feelings 0.3 0.5 0.6 0.8 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.4 1.9 3.6 -0.5 -1.9
Relative age voice broke 0.2 0.2 0.5 -0.7 0.2
Taking other prescription medications 0.7 1.1 1.5 -0.8 -1.2
Age when periods started (menarche) 0.2 0.5 0.8 0.9 0.4
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 1.9 -0.5 -1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.6 2.3 1.5 0.9
Tinnitus: Yes, but not now, but have in the past 1.7 1.8 3.0 -0.8 -1.7
Qualifications: CSEs or equivalent 0.5 0.6 1.3 -0.1 -1.1
Serious illness, injury or assault to yourself 3.0 3.6 6.0 1.1 -2.4
High blood pressure 0.6 1.8 3.2 -0.5 -1.8
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.3 0.3 0.6
Multivitamins +/- minerals 1.0 1.3 2.0 0.7 1.4
Stomach or abdominal pain in last month 2.1 2.6 4.1 -2.0 1.1
Supplements: Glucosamine 2.7 3.5 6.1 -1.0 2.5
Diverticular disease/diverticulitis (self-reported) 2.5 2.9 5.7 -0.4 2.4
Medication: Atenolol 0.4 0.4 0.7 0.8 -0.5
Medication: Levothyroxine sodium 0.5 0.8 1.7 0.0 -1.3
Sitting height 1.2 8.3 15.6 -1.0 -4.0
Chronic bronchitis/emphysema (father) 0.5 0.6 1.1 -0.2 -1.1
High blood pressure (mother) 0.4 0.6 1.2 1.1 -0.1
Body mass index (BMI) 0.5 2.0 3.9 0.3 -2.0
Impedance of leg (left) 0.2 1.0 1.2 -1.1 -0.9
Leg predicted mass (left) 0.7 3.7 7.3 0.3 -2.7
Trunk fat mass 1.7 7.3 14.6 -0.1 -3.8
Waist circumference 2.0 7.3 14.7 -0.0 -3.8
Number of incorrect matches in round 0.1 0.2 0.3 -0.6 0.2
Past tobacco smoking 0.5 0.9 1.8 1.3 0.1
Alcohol usually taken with meals 1.4 2.3 3.1 1.8 1.2
Nervous feelings 0.1 0.2 0.4 -0.6 0.2
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.2 2.8 -1.7 -1.3
Hearing difficulty/problems with background noise 1.1 1.8 3.0 0.7 -1.7
Hair/balding pattern: Pattern 2 1.2 1.5 2.4 -1.5 -0.8
Had menopause 1.3 1.6 3.1 0.4 1.8
Had other major operations 0.0 0.0 0.0 0.2 0.1
Forced vital capacity (FVC) 0.4 1.7 3.2 0.4 1.8
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 1.4 1.2 0.9
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.2 0.4 0.2
Qualifications: None of the above 0.9 2.0 3.0 -1.7 1.0
Financial difficulties in last 2 years 0.3 0.4 0.7 0.0 -0.9
Mouth/teeth dental problems 0.6 0.9 1.7 -1.3 -0.4
Heart attack 1.7 2.1 3.0 -1.7 1.1
Allergy 0.1 0.2 0.3 0.6 0.4
Pain all over the body in last month 3.3 3.5 6.2 0.9 -2.5
Diabetes (self-reported) 2.5 3.9 7.8 -0.1 -2.8
Hayfever/allergic rhinitis (self-reported) 0.5 0.6 1.1 1.0 0.4
Medication: Ramipril 0.6 0.8 1.6 -0.2 -1.2
Medication: Simvastatin 0.5 0.8 1.0 0.8 -1.0
Fluid intelligence score 3.4 7.0 13.0 1.0 3.6
Illnesses of siblings 1.5 2.1 2.3 1.5 1.3
Neuroticism score 0.3 0.6 0.9 -0.6 -0.9
Weight 1.2 5.8 11.4 -0.3 -3.4
Impedance of arm (right) 0.1 0.4 0.8 -0.3 -0.9
Arm fat percentage (right) 0.9 3.7 7.2 0.3 -2.7
Trunk fat-free mass 0.4 2.0 4.0 -0.1 -2.0
Hip circumference 0.2 0.8 1.5 0.2 -1.2
Time employed in main current job 0.2 0.2 0.5 0.7 0.0
Alcohol intake versus 10 years previously 2.6 3.8 3.9 -1.9 -2.0
Father’s age at death 1.3 1.8 3.6 -0.0 1.9
Worrier / anxious feelings 0.6 1.1 1.9 0.5 1.4
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 1.1 -0.7 -1.0
Falls in the last year 0.1 0.2 0.2 0.4 -0.4
Hair/balding pattern: Pattern 3 0.3 0.5 0.9 1.0 -0.2
Number of live births 2.0 2.8 4.2 -1.2 2.1
Forced expiratory volume in 1-second (FEV1) 1.0 3.4 6.8 0.1 2.6
Pulse rate 0.5 0.9 1.5 -0.6 -1.2
Happiness 1.8 2.1 3.3 -1.0 -1.8
Noisy workplace 5.1 6.3 6.4 -2.5 -2.5
Qualifications: A levels/AS levels or equivalent 2.7 5.9 8.4 2.9 1.9
Serious illness, injury or assault of a close relative in last 2 years 1.9 2.2 3.0 1.7 1.2
Mouth/teeth dental problems: Dentures 0.1 0.2 0.4 0.6 -0.1
Asthma 0.1 0.2 0.3 -0.5 0.5
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 0.6 0.8 -0.3
Medication: Cholesterol lowering 0.8 1.2 1.5 1.2 -0.9
Depression (self-reported) 1.2 1.4 2.2 0.8 -1.5
Medication: Lansoprazole 0.3 0.3 0.6 0.8 0.2
Prospective memory result 0.2 0.3 0.6 0.0 -0.8
Lung cancer (father) 0.7 0.8 1.5 -0.0 -1.2
Illnesses of mother 0.4 0.5 0.6 -0.7 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.1 6.2 0.0 2.5
Pulse wave Arterial Stiffness index 0.3 0.3 0.7 -0.8 0.0
Impedance of arm (left) 0.1 0.5 0.9 -0.3 -0.9
Arm fat mass (right) 1.2 5.0 10.0 0.1 -3.2
Trunk predicted mass 0.4 2.0 4.1 -0.1 -2.0
Standing height 0.6 6.3 11.6 -1.0 -3.4
Length of working week for main job 0.0 0.0 0.0 0.1 -0.0
Exposure to tobacco smoke at home 1.2 1.3 2.7 0.1 -1.6
Breastfed as a baby 0.3 0.4 0.7 0.8 -0.3
Tense / ‘highly strung’ 1.8 3.0 3.7 -1.5 -1.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.5 0.4 -0.7
Hair/balding pattern: Pattern 4 0.2 0.4 0.5 0.5 0.7
Birth weight of first child 0.3 0.5 0.8 -0.3 -0.9
Peak expiratory flow (PEF) 2.9 6.7 11.1 -1.6 3.3
Pulse wave reflection index 0.8 1.0 1.6 0.6 1.3
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.1 -0.2 0.4
Loud music exposure frequency 1.0 1.1 1.5 -1.2 -0.9
Qualifications: O levels/GCSEs or equivalent 1.9 3.0 5.0 1.0 2.2
Mouth/teeth dental problems: Bleeding gums 1.4 1.8 3.6 1.9 0.1
Blood clot in the leg (DVT) 0.7 0.9 1.6 -0.3 -1.3
Medication: Paracetamol 0.3 0.5 1.1 -0.1 1.0
Headache pain in last month 1.3 2.3 4.5 -2.1 0.3
Medication for cholesterol, blood pressure or diabetes 2.1 3.4 4.6 -1.5 2.1
Glaucoma (self-reported) 0.1 0.1 0.2 0.1 -0.5
Gout (self-reported) 2.1 2.8 4.7 2.2 -1.0
Hypothyroidism/myxoedema (self-reported) 0.4 0.9 1.3 0.6 -1.2
Medication: Amlodipine 0.1 0.2 0.3 0.5 -0.3
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.0 -0.3 -1.0
Birth weight 1.6 3.5 4.8 -1.5 -2.2
Chronic bronchitis/emphysema (mother) 1.2 1.4 2.3 -1.5 -0.7
High blood pressure (siblings) 1.3 1.9 3.6 -0.4 -1.9
Forced vital capacity (FVC), Best measure 0.5 1.9 3.7 0.1 1.9
Body fat percentage 1.5 5.8 11.5 -0.1 -3.4
Leg fat percentage (right) 0.8 2.8 5.5 -0.3 -2.4
Arm fat-free mass (right) 0.6 3.1 6.0 -0.4 -2.5
Exposure to tobacco smoke outside home 0.8 1.1 1.9 1.4 -0.5
Comparative body size at age 10 0.2 0.7 1.3 -0.1 1.1
Number of full brothers 2.8 3.5 3.8 -1.8 2.0
Worry too long after embarrassment 0.4 0.6 0.9 -0.6 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 1.9 -0.8 -1.4
Wheeze or whistling in the chest in last year 0.3 0.6 1.1 -0.0 -1.1
Number of children fathered 0.1 0.1 0.2 -0.4 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 3.1 3.6 4.1 1.8 -2.0
Age at first live birth 1.8 3.2 6.2 2.5 -0.5
Pulse wave peak to peak time 0.3 0.3 0.5 0.7 -0.4
Health satisfaction 0.8 1.1 2.0 -0.3 -1.4
Shortness of breath walking on level ground 3.1 3.7 6.2 -1.1 -2.5
Qualifications: College or University degree 1.9 5.9 11.9 3.4 0.1
Eye problems/disorders: None of the above 4.7 5.5 5.6 -2.4 2.3
Mouth/teeth dental problems: Loose teeth 1.0 1.2 1.8 -0.7 -1.3
Emphysema/chronic bronchitis 1.5 1.7 2.1 -1.4 -1.2
Medication for pain relief, constipation, heartburn 0.3 0.5 0.8 -0.9 -0.4
Neck or shoulder pain in last month 1.0 1.5 2.1 -1.5 -0.9
Medication: Blood pressure 0.9 1.7 1.9 1.2 -1.4
Angina (self-reported) 0.1 0.2 0.2 -0.5 -0.4
Migraine (self-reported) 0.2 0.2 0.4 0.2 -0.6
Medication: Ibuprofen 0.5 0.6 1.2 1.1 0.0
Medication: Allopurinol 1.4 1.9 3.3 1.8 -0.7
Medication: Omeprazole 0.3 0.3 0.6 -0.2 -0.8
Medication: Seretide 50 evohaler 1.1 1.3 2.5 -1.6 0.3
Mean time to correctly identify matches 1.8 3.4 6.6 -0.4 -2.6
Heart disease (mother) 0.9 1.1 2.0 0.4 1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.7 3.2 6.4 0.2 2.5
Whole body fat mass 1.8 7.4 14.7 -0.3 -3.8
Leg fat mass (right) 1.4 5.4 10.7 -0.4 -3.3
Arm predicted mass (right) 0.5 2.7 5.3 -0.4 -2.3
Pulse rate, automated reading 1.0 3.2 6.2 0.3 -2.5
Alcohol intake frequency. 0.7 1.6 3.2 -1.8 -0.2
Comparative height size at age 10 0.1 0.6 1.1 -0.3 -1.0
Number of full sisters 1.5 1.8 2.7 -0.9 -1.6
Suffer from ‘nerves’ 0.6 1.0 1.3 -1.1 -0.8
Overall health rating 1.9 4.2 7.2 -1.1 -2.7
Chest pain or discomfort 2.0 2.9 4.8 -1.0 -2.2
Had major operations 0.5 0.6 1.1 0.3 1.1
Age at last live birth 0.9 1.3 2.6 1.6 -0.3
Family relationship satisfaction 3.0 3.7 5.7 -2.4 -1.3
Leg pain on walking 1.0 1.3 1.9 -0.8 -1.4
Qualifications: NVQ or HND or HNC or equivalent 2.6 3.2 6.1 -0.5 -2.5
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.2 -0.4 0.5
Illness, injury, bereavement, stress in last 2 years 2.1 2.6 4.2 -1.0 2.1
Medication: Aspirin 0.7 0.9 1.4 0.7 -1.2
Supplements: Vitamin C 1.6 1.9 3.3 -0.7 -1.8
Knee pain experienced in last month 1.5 2.3 4.6 0.1 -2.1
Hypertension (Self-reported) 0.9 2.4 4.5 -0.6 -2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.1 0.2 -1.0
Illnesses of father: Heart disease 0.3 0.4 0.5 0.7 0.5
Illnesses of siblings: Diabetes 1.9 2.3 2.7 -1.6 -1.4
Smoking status: Previous 0.7 1.1 1.2 -1.0 1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 1.5 -0.6 -1.2
Whole body fat-free mass 0.6 3.3 6.6 0.0 -2.6
Leg fat-free mass (right) 0.8 4.0 8.0 0.2 -2.8
Arm fat percentage (left) 1.1 4.3 8.4 0.4 -2.9
Average weekly red wine intake 1.3 1.9 3.2 0.7 -1.8
Handedness (chirality/laterality): Left-handed 6.1 7.3 14.1 0.7 -3.8
Mood swings 1.8 3.3 6.5 -0.2 -2.6
Loneliness, isolation 2.2 3.0 4.3 -1.3 -2.1
Long-standing illness, disability or infirmity 2.4 3.7 7.0 -0.6 -2.6
Ever had bowel cancer screening 1.3 1.5 2.9 -0.3 -1.7
Diabetes diagnosed by doctor 2.5 4.1 8.1 -0.3 -2.8
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 1.1 -0.4 -1.1
Friendships satisfaction 2.0 2.4 3.2 -1.8 -1.3
Qualifications: nursing, teaching 0.3 0.4 0.4 0.6 0.7
Commuting to job workplace: Walk 1.4 1.5 2.5 0.7 -1.6
Eye problems/disorders: Cataract 0.6 0.7 1.3 1.1 -0.1
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 2.6 0.1 1.6
Medication for cholesterol 0.8 1.2 1.5 1.2 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.1 2.0 -1.4 0.5
Back pain experienced in last month 0.8 1.2 2.0 -1.4 -0.5
Mineral and other dietary supplements 1.8 2.4 4.8 -0.3 -2.2
Breast cancer (self-reported) 0.3 0.3 0.6 0.1 0.8
Asthma (self-reported) 0.1 0.3 0.5 -0.3 0.7
Osteoporosis (self-reported) 0.6 0.8 1.3 1.1 -0.5
Osteoarthritis (self-reported) 0.2 0.3 0.5 0.7 -0.3
Medication: Aspirin 0.2 0.3 0.4 0.6 -0.4
Medication: Gliclazide 0.3 0.3 0.3 -0.6 -0.5
Illnesses of father: None of the above (group 1) 0.0 0.0 0.1 -0.3 0.0
Smoking status: Current 0.8 1.2 2.0 0.6 -1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.0 6.4 10.7 1.4 3.3
Whole body water mass 0.5 2.9 5.8 0.1 -2.4
Leg predicted mass (right) 0.8 4.2 8.4 0.1 -2.9
Arm fat mass (left) 1.3 5.1 10.2 0.1 -3.2
Number of self-reported non-cancer illnesses 2.8 4.9 8.2 -1.3 -2.9
Average weekly champagne plus white wine intake 0.1 0.1 0.2 -0.4 -0.2
Miserableness 0.1 0.2 0.3 0.6 -0.1
Guilty feelings 0.5 0.7 1.0 0.7 -1.0
Wears glasses or contact lenses 0.5 0.6 0.7 -0.8 -0.6
Ever taken oral contraceptive pill 1.3 1.5 2.4 -1.5 0.8
Hearing aid user 1.4 1.5 1.6 -1.3 -1.2
Mother’s age at death 0.8 1.0 1.6 1.3 0.7
Financial situation satisfaction 0.8 0.9 1.9 -0.1 -1.4
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.4 -0.6 0.3
Commuting to job workplace: Public transport 0.5 0.6 0.9 0.9 -0.5
Eye problems/disorders: Glaucoma 0.2 0.2 0.4 0.0 -0.7
Medication: Blood pressure 1.3 2.6 4.9 -0.4 -2.2
Pain type(s) experienced in last month: Hip pain 1.0 1.2 1.6 -1.3 0.9
Supplements: Fish oil (including cod liver oil) 2.9 3.8 7.5 0.1 2.7
High cholesterol (Self-reported) 0.3 0.6 0.9 0.4 -1.0
Medication: Bendroflumethiazide 0.7 1.0 1.9 -0.3 -1.4
Medication: Paracetamol 0.5 0.7 1.2 0.5 1.1
Medication: Lisinopril 2.4 3.0 5.4 0.8 -2.3
Medication: Atorvastatin 0.6 0.7 1.4 1.2 0.1
Illnesses of father: High blood pressure 0.3 0.4 0.7 -0.4 -0.8
Alcohol drinker status: Never 0.1 0.1 0.2 -0.0 0.4
Ever smoked 0.7 1.3 1.7 -1.3 -0.9
Basal metabolic rate 0.8 4.4 8.8 0.0 -3.0
Leg fat percentage (left) 1.2 4.2 8.3 -0.5 -2.9
Arm fat-free mass (left) 0.5 2.8 5.5 -0.1 -2.4
Number of operations (self-reported) 0.4 0.6 1.2 0.3 -1.1
Average weekly beer plus cider intake 2.7 3.9 4.4 -1.8 -2.1
Irritability 0.5 0.8 1.3 -0.7 -1.1
Risk taking 6.8 9.9 18.7 1.1 -4.3
Ever had prostate specific antigen (PSA) test 0.0 0.0 0.1 0.1 -0.3
Fractured/broken bones in last 5 years 1.7 2.2 2.8 1.3 -1.7
Age started oral contraceptive pill 0.9 1.1 2.2 0.2 1.5
Diastolic blood pressure, automated reading 0.9 2.7 5.4 0.1 -2.3
Ever depressed for a whole week 0.4 0.5 0.7 -0.9 0.5
Unable to work because of sickness or disability 4.3 5.6 9.9 -1.1 -3.1
Commuting to job workplace: Cycle 1.1 1.3 2.3 1.5 0.6
Myopia 0.1 0.1 0.2 0.1 0.5
Vascular/heart problems diagnosed by doctor 0.5 1.5 2.4 0.8 1.5
Cholesterol lowering medication 0.5 0.8 1.3 0.5 -1.1
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 0.2 -0.1 -0.5
Pain experienced in last month 0.9 1.4 2.4 1.5 0.7
Supplements: Calcium 2.1 2.3 3.2 -1.2 1.8
Basal cell carcinoma (self-reported) 1.8 2.1 3.3 -1.8 -0.9
Heart attack/myocardial infarction (self-reported) 1.5 2.0 3.0 -1.7 1.0
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.4 -0.3 -1.2
Heart disease (siblings) 0.7 0.8 1.6 -1.3 0.2
Alcohol drinker status: Previous 0.7 0.8 1.7 -1.3 -0.1
Pack years of smoking 0.8 1.1 2.2 -1.5 0.3
Impedance of whole body 0.2 1.2 1.3 -1.0 -1.1
Leg fat mass (left) 1.5 6.0 11.7 -0.5 -3.4
Arm predicted mass (left) 0.4 2.2 4.4 -0.2 -2.1