[Hub]/) : Traits : Lung FVC : ← →

chr1:112,312,154-113,941,737

Best TWAS P=1.94e-10 · Best GWAS P=9.75e-09 conditioned to 0.00198

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ST7L	0.25	0.33	bslmm	401	0.34	3.4e-43	5.4	5.8	5.0e-09	0.48	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	ST7L	0.27	0.32	enet	17	0.34	2.6e-28	5.3	5.7	1.2e-08	0.45	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	CAPZA1	0.09	0.06	lasso	3	0.05	5.0e-05	5.5	5.4	5.3e-08	0.37	0.02	0.98	FALSE
4	GTEx	Adipose Visceral Omentum	ST7L	0.33	0.32	enet	29	0.32	4.2e-17	5.3	6.1	1.1e-09	0.56	0.03	0.97	FALSE
5	GTEx	Adrenal Gland	ST7L	0.37	0.40	lasso	5	0.40	1.5e-15	5.3	5.4	5.5e-08	0.40	0.03	0.97	FALSE
6	GTEx	Artery Aorta	ST7L	0.34	0.38	enet	17	0.37	1.6e-21	5.3	5.5	3.8e-08	0.40	0.03	0.97	FALSE
7	GTEx	Artery Coronary	ST7L	0.43	0.33	enet	12	0.20	2.0e-07	5.5	5.5	4.8e-08	0.36	0.02	0.98	FALSE
8	GTEx	Artery Tibial	ST7L	0.22	0.21	enet	13	0.21	3.8e-16	5.3	5.9	3.1e-09	0.49	0.03	0.97	FALSE
9	GTEx	Brain Caudate basal ganglia	ST7L	0.19	0.14	lasso	2	0.12	1.9e-04	5.4	5.4	5.8e-08	0.36	0.03	0.89	FALSE
10	GTEx	Brain Cerebellar Hemisphere	ST7L	0.24	0.16	lasso	2	0.12	5.1e-04	5.3	5.7	1.1e-08	0.50	0.03	0.70	FALSE
11	GTEx	Brain Cerebellum	RP4-671G15.2	0.25	0.25	lasso	5	0.21	6.3e-07	5.3	-5.4	5.9e-08	-0.37	0.02	0.97	FALSE
12	GTEx	Brain Cortex	ST7L	0.29	0.18	lasso	5	0.20	3.1e-06	5.3	5.7	1.2e-08	0.53	0.03	0.93	FALSE
13	GTEx	Brain Cortex	CAPZA1	0.21	0.16	lasso	6	0.11	6.7e-04	5.4	5.5	4.5e-08	0.33	0.03	0.84	FALSE
14	GTEx	Brain Cortex	WNT2B	0.36	0.19	lasso	5	0.23	5.5e-07	4.9	5.4	5.5e-08	0.80	0.05	0.93	FALSE
15	GTEx	Brain Frontal Cortex BA9	WNT2B	0.29	0.28	lasso	3	0.29	2.6e-08	5.0	5.3	1.3e-07	0.82	0.05	0.94	FALSE
16	GTEx	Brain Nucleus accumbens basal ganglia	ST7L	0.31	0.10	lasso	7	0.05	2.1e-02	-5.0	5.2	1.6e-07	0.34	0.03	0.74	FALSE
17	GTEx	Breast Mammary Tissue	ST7L	0.25	0.30	enet	11	0.31	1.9e-16	5.4	5.4	7.7e-08	0.38	0.02	0.98	FALSE
18	GTEx	Breast Mammary Tissue (Male)	ST7L	0.23	0.20	lasso	7	0.14	4.9e-04	5.3	5.3	8.9e-08	0.37	0.03	0.86	FALSE
19	GTEx	Breast Mammary Tissue (Female)	ST7L	0.33	0.27	lasso	3	0.26	3.0e-08	5.3	5.4	7.1e-08	0.39	0.03	0.97	FALSE
20	GTEx	Cells EBV-transformed lymphocytes	ST7L	0.33	0.20	enet	30	0.14	2.1e-05	5.3	5.6	1.8e-08	0.31	0.03	0.96	FALSE
21	GTEx	Cells Transformed fibroblasts	ST7L	0.54	0.64	enet	13	0.66	1.3e-64	5.3	5.8	6.1e-09	0.48	0.03	0.97	FALSE
22	GTEx	Colon Transverse	ST7L	0.22	0.19	enet	9	0.16	3.4e-08	5.3	6.4	1.9e-10	0.47	0.03	0.97	TRUE
23	GTEx	Esophagus Gastroesophageal Junction	ST7L	0.32	0.30	enet	31	0.30	1.9e-11	5.3	6.0	2.0e-09	0.44	0.02	0.98	FALSE
24	GTEx	Esophagus Mucosa	ST7L	0.18	0.20	lasso	3	0.19	8.9e-13	5.3	5.6	2.1e-08	0.47	0.03	0.97	FALSE
25	GTEx	Esophagus Muscularis	ST7L	0.26	0.33	lasso	5	0.33	1.4e-20	5.3	5.4	6.4e-08	0.39	0.03	0.97	FALSE
26	GTEx	Esophagus Muscularis	RHOC	0.15	0.00	enet	9	0.00	4.8e-01	5.4	6.4	2.0e-10	0.31	0.03	0.52	FALSE
27	GTEx	Heart Atrial Appendage	ST7L	0.25	0.08	enet	18	0.11	1.1e-05	5.3	5.8	6.9e-09	0.56	0.03	0.97	FALSE
28	GTEx	Heart Left Ventricle	ST7L	0.12	0.13	lasso	3	0.12	5.2e-07	5.3	5.3	9.2e-08	0.38	0.02	0.97	FALSE
29	GTEx	Lung	ST7L	0.18	0.25	lasso	4	0.25	4.5e-19	5.4	5.5	4.4e-08	0.37	0.02	0.98	FALSE
30	GTEx	Muscle Skeletal	ST7L	0.04	0.05	enet	6	0.02	4.3e-03	5.4	5.4	6.4e-08	0.38	0.03	0.97	FALSE
31	GTEx	Nerve Tibial	ST7L	0.27	0.36	enet	24	0.32	1.4e-23	5.4	5.5	3.1e-08	0.33	0.02	0.98	FALSE
32	GTEx	Pituitary	ST7L	0.31	0.18	lasso	7	0.18	3.0e-05	5.1	5.4	8.5e-08	0.86	0.02	0.95	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	ST7L	0.14	0.10	enet	8	0.06	2.6e-04	5.3	5.8	7.4e-09	0.53	0.03	0.97	FALSE
34	GTEx	Skin Sun Exposed Lower leg	ST7L	0.12	0.12	lasso	1	0.11	1.7e-09	5.4	5.4	5.7e-08	0.36	0.02	0.98	FALSE
35	GTEx	Small Intestine Terminal Ileum	ST7L	0.34	0.15	lasso	6	0.11	1.9e-03	-5.2	5.2	1.5e-07	0.33	0.03	0.69	FALSE
36	GTEx	Stomach	ST7L	0.21	0.24	lasso	3	0.23	2.6e-11	5.4	5.7	1.0e-08	0.47	0.02	0.97	FALSE
37	GTEx	Testis	ST7L	0.46	0.55	lasso	6	0.55	7.4e-29	5.3	5.5	3.5e-08	0.42	0.02	0.98	FALSE
38	GTEx	Thyroid	ST7L	0.15	0.20	lasso	2	0.19	1.4e-14	5.3	5.3	1.0e-07	0.38	0.03	0.97	FALSE
39	GTEx	Whole Blood	ST7L	0.09	0.08	lasso	2	0.08	1.5e-07	5.3	5.3	9.1e-08	0.38	0.03	0.97	FALSE
40	METSIM	Adipose	ST7L	0.22	0.25	enet	11	0.25	1.0e-37	5.3	5.7	1.2e-08	0.50	0.03	0.97	FALSE
41	ROSMAP	Brain Pre-frontal Cortex	WNT2B	0.34	0.40	enet	30	0.42	1.5e-59	4.9	5.4	8.2e-08	0.77	0.23	0.76	FALSE
42	YFS	Blood	ST7L	0.09	0.10	lasso	8	0.10	2.4e-32	5.3	5.4	6.3e-08	0.38	0.03	0.97	FALSE
43	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ST7L	0.21	0.22	blup	56	0.21	1.7e-17	5.3	5.5	4.3e-08	0.42	0.02	0.98	FALSE
44	The Cancer Genome Atlas	Breast Invasive Carcinoma	ST7L	0.23	0.36	lasso	5	0.36	2.8e-76	5.3	5.5	3.6e-08	0.44	0.02	0.98	FALSE
45	The Cancer Genome Atlas	Colon Adenocarcinoma	ST7L	0.33	0.19	lasso	3	0.21	1.7e-12	5.3	5.9	3.2e-09	0.57	0.02	0.98	FALSE
46	The Cancer Genome Atlas	Glioblastoma Multiforme	ST7L	0.27	0.20	blup	55	0.18	5.0e-06	5.4	5.7	1.2e-08	0.44	0.02	0.97	FALSE
47	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ST7L	0.13	0.17	lasso	3	0.17	1.5e-18	5.3	5.4	7.1e-08	0.39	0.02	0.98	FALSE
48	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ST7L	0.18	0.27	blup	56	0.28	2.4e-31	5.3	6.2	6.5e-10	0.57	0.02	0.98	FALSE
49	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ST7L	0.14	0.09	enet	11	0.13	6.5e-08	5.3	5.3	1.0e-07	0.40	0.02	0.98	FALSE
50	The Cancer Genome Atlas	Brain Lower Grade Glioma	ST7L	0.21	0.36	lasso	6	0.37	1.7e-43	5.3	5.3	1.1e-07	0.38	0.02	0.98	FALSE
51	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PPM1J	0.07	0.02	blup	39	0.03	1.1e-02	5.4	-5.5	3.8e-08	-0.21	0.01	0.73	FALSE
52	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ST7L	0.23	0.24	lasso	2	0.22	7.4e-11	5.3	5.2	1.8e-07	0.35	0.02	0.98	FALSE
53	The Cancer Genome Atlas	Lung Adenocarcinoma	ST7L	0.26	0.35	enet	17	0.36	2.6e-43	5.3	5.9	3.7e-09	0.50	0.02	0.98	FALSE
54	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ST7L	0.05	0.09	lasso	2	0.08	1.4e-09	5.3	5.3	1.5e-07	0.37	0.02	0.98	FALSE
55	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ST7L	0.12	0.18	enet	12	0.17	9.3e-12	5.3	5.4	5.3e-08	0.39	0.02	0.98	FALSE
56	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ST7L	0.39	0.36	lasso	7	0.35	1.8e-15	5.3	5.5	4.4e-08	0.42	0.02	0.98	FALSE
57	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ST7L	0.28	0.28	enet	12	0.26	1.0e-10	5.3	5.8	7.9e-09	0.46	0.02	0.98	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	MOV10	0.03	0.00	lasso	9	0.00	9.9e-02	5.0	5.6	1.8e-08	0.47	0.01	0.69	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	ST7L	0.31	0.43	enet	12	0.42	3.4e-47	5.3	5.6	1.6e-08	0.44	0.02	0.98	FALSE
60	The Cancer Genome Atlas	Soft Tissue Sarcoma	ST7L	0.11	0.13	lasso	7	0.12	1.5e-07	5.3	5.8	4.9e-09	0.51	0.02	0.98	FALSE
61	The Cancer Genome Atlas	Skin Cutaneous Melanoma	ST7L	0.29	0.29	enet	5	0.26	1.6e-07	5.4	5.4	7.5e-08	0.35	0.02	0.97	FALSE
62	The Cancer Genome Atlas	Stomach Adenocarcinoma	ST7L	0.23	0.23	lasso	4	0.23	1.3e-16	5.3	5.7	1.5e-08	0.44	0.02	0.98	FALSE
63	The Cancer Genome Atlas	Thyroid Carcinoma	MOV10	0.06	0.06	lasso	7	0.05	9.4e-06	5.5	5.4	8.5e-08	0.83	0.02	0.97	FALSE
64	The Cancer Genome Atlas	Thyroid Carcinoma	ST7L	0.51	0.62	lasso	3	0.62	1.1e-75	5.3	5.3	1.0e-07	0.38	0.02	0.98	FALSE