Best TWAS P=1.53e-13 · Best GWAS P=6.91e-14 conditioned to 0.0625
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | RPS20 | 0.26 | 0.07 | enet | 17 | 0.10 | 5.4e-04 | -7.25 | -5.6 | 2.3e-08 | 0.76 | 0.03 | 0.93 | FALSE |
| 2 | GTEx | Esophagus Muscularis | RPS20 | 0.12 | 0.04 | lasso | 6 | 0.05 | 7.2e-04 | -7.26 | -7.4 | 1.5e-13 | 0.91 | 0.02 | 0.98 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | RPS20 | 0.18 | 0.03 | enet | 12 | 0.07 | 1.5e-04 | -7.17 | -6.9 | 4.2e-12 | 0.76 | 0.01 | 0.95 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | LYN | 0.10 | 0.05 | lasso | 10 | 0.09 | 1.1e-11 | 0.82 | 5.3 | 1.1e-07 | -0.61 | 0.25 | 0.75 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RPS20 | 0.04 | 0.03 | lasso | 3 | 0.04 | 1.3e-04 | -4.57 | -5.1 | 2.7e-07 | 0.70 | 0.00 | 0.96 | FALSE |