[Hub]/) : Traits : Lung FVC : ← →

chr9:14,857,740-16,758,776

Best TWAS P=1.41e-12 · Best GWAS P=8.36e-12 conditioned to 0.0647

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial CCDC171 0.10 0.09 enet 9 0.12 7.2e-10 -4.6 5.1 3.1e-07 0.61 0.86 0.14 FALSE
2 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 -5.4 6.0 2.1e-09 0.84 0.44 0.55 FALSE
3 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 6.3 7.1 1.4e-12 0.81 0.24 0.72 TRUE
4 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 5.7 6.2 5.6e-10 0.84 0.22 0.76 FALSE
5 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 5.5 5.8 6.4e-09 0.89 0.21 0.68 FALSE
6 GTEx Lung CCDC171 0.13 0.03 enet 9 0.01 5.0e-02 -5.1 6.0 1.9e-09 0.65 0.38 0.41 FALSE
7 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 5.5 5.6 1.8e-08 0.84 0.74 0.26 FALSE
8 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 -5.6 -5.8 6.6e-09 -0.79 0.23 0.30 FALSE
9 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 -5.0 5.7 1.5e-08 0.85 0.17 0.77 FALSE
10 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 -5.5 5.2 2.1e-07 0.75 0.94 0.06 FALSE