Best TWAS P=1.1e-10 · Best GWAS P=7.7e-09 conditioned to 0.000183
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CACFD1 | 0.10 | 0.03 | lasso | 4 | 0.03 | 1.7e-03 | 3.2 | -5.2 | 1.5e-07 | 0.69 | 0.01 | 0.95 | FALSE |
| 2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ABO | 0.23 | 0.23 | lasso | 2 | 0.24 | 2.2e-11 | -5.4 | -5.3 | 1.1e-07 | 0.37 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ABO | 0.41 | 0.17 | enet | 12 | 0.25 | 3.0e-09 | 4.3 | -5.3 | 1.1e-07 | 0.27 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | ABO | 0.23 | 0.07 | blup | 44 | 0.12 | 4.3e-04 | -5.4 | -6.5 | 1.1e-10 | 0.35 | 0.00 | 0.75 | TRUE |