Best TWAS P=3.68e-13 · Best GWAS P=2.37e-15 conditioned to 0.103
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | CAMK1D | 0.28 | 0.24 | enet | 25 | 0.24 | 2.3e-18 | -6.6 | -6.7 | 1.6e-11 | 0.51 | 0.95 | 0.05 | TRUE |
| 2 | GTEx | Whole Blood | PROSER2 | 0.11 | 0.07 | enet | 12 | 0.07 | 2.5e-07 | -5.4 | -5.1 | 2.7e-07 | 0.06 | 0.99 | 0.00 | TRUE |
| 3 | GTEx | Whole Blood | CAMK1D | 0.14 | 0.01 | enet | 26 | 0.04 | 2.5e-04 | -6.6 | -5.6 | 2.2e-08 | 0.63 | 0.21 | 0.72 | FALSE |
| 4 | NTR | Blood | CAMK1D | 0.10 | 0.09 | bslmm | 900 | 0.08 | 4.4e-25 | -6.6 | -6.7 | 1.9e-11 | 0.59 | 0.95 | 0.05 | FALSE |
| 5 | NTR | Blood | CDC123 | 0.06 | 0.04 | bslmm | 537 | 0.04 | 4.7e-14 | -7.9 | -7.3 | 3.7e-13 | 0.91 | 0.00 | 1.00 | TRUE |
| 6 | YFS | Blood | CAMK1D | 0.27 | 0.23 | bslmm | 875 | 0.26 | 7.7e-86 | -6.6 | -6.5 | 6.2e-11 | 0.63 | 0.95 | 0.05 | FALSE |
| 7 | YFS | Blood | CDC123 | 0.08 | 0.03 | enet | 35 | 0.06 | 9.6e-19 | -6.6 | -5.3 | 1.1e-07 | 0.65 | 0.40 | 0.60 | FALSE |
| 8 | YFS | Blood | NUDT5 | 0.13 | 0.12 | enet | 40 | 0.13 | 1.1e-41 | -6.6 | -7.2 | 5.4e-13 | 0.71 | 0.95 | 0.05 | FALSE |
| 9 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CDC123 | 0.26 | 0.07 | lasso | 4 | 0.07 | 1.4e-03 | -5.7 | 6.4 | 1.6e-10 | -0.65 | 0.10 | 0.20 | FALSE |
| 10 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CDC123 | 0.08 | 0.00 | blup | 64 | 0.03 | 4.0e-03 | -3.6 | -6.7 | 2.1e-11 | 0.64 | 0.01 | 0.15 | FALSE |
| 11 | The Cancer Genome Atlas | Soft Tissue Sarcoma | NUDT5 | 0.08 | 0.07 | enet | 8 | 0.07 | 8.2e-05 | -3.6 | -6.1 | 1.4e-09 | 0.51 | 0.83 | 0.05 | FALSE |