[Hub]/) : Traits : Lung FVC :

chr1:195,927,451-197,488,569

Best TWAS P=3.86e-11 · Best GWAS P=2.38e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CFH 0.03 0.03 blup 267 0.02 2.8e-03 3.0 5.1 3.1e-07 -0.33 0.13 0.05 FALSE
2 GTEx Adipose Subcutaneous CFH 0.10 0.03 enet 25 0.03 2.1e-03 -5.3 -6.1 1.1e-09 0.60 0.15 0.83 FALSE
3 GTEx Adipose Subcutaneous CFHR1 0.16 0.08 lasso 5 0.08 2.5e-07 -5.2 -5.2 2.0e-07 0.57 0.71 0.29 FALSE
4 GTEx Nerve Tibial CFH 0.16 0.06 enet 27 0.15 5.5e-11 -5.1 -5.1 3.0e-07 0.53 0.64 0.35 FALSE
5 METSIM Adipose CFH 0.03 0.00 blup 263 0.01 7.0e-03 -5.3 -5.9 2.7e-09 0.52 0.35 0.42 FALSE
6 METSIM Adipose CFHR3 0.17 0.30 bslmm 237 0.31 7.8e-47 5.8 -6.6 4.2e-11 0.71 0.35 0.65 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CFHR3 0.07 0.00 blup 10 0.05 1.8e-03 2.3 -5.1 2.9e-07 0.43 0.00 0.12 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma CFHR3 0.09 0.03 lasso 2 0.03 4.9e-03 -5.5 -6.3 3.9e-10 0.76 0.00 0.51 FALSE
9 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CFHR1 0.33 0.24 lasso 2 0.26 1.4e-12 -6.6 6.1 1.3e-09 -0.96 0.00 1.00 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CFHR3 0.14 0.15 lasso 1 0.14 3.9e-07 -6.6 6.6 3.9e-11 -1.00 0.00 1.00 TRUE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CFHR4 0.22 0.08 lasso 3 0.14 3.8e-07 -5.4 6.3 3.4e-10 -0.72 0.01 0.98 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CFH 0.03 0.01 enet 8 0.03 8.5e-04 5.6 -6.3 4.0e-10 0.75 0.02 0.78 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma CFHR3 0.12 0.03 enet 4 0.07 5.0e-08 5.5 -5.3 1.3e-07 0.63 0.09 0.80 FALSE