Hub : Genes

CFHR3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 METSIM Adipose 0.1720 0.0393 0.0e+00 0.301 0.294 0.306 0.307 0.300 1.1e-45 1.6e-44 1.2e-46 7.8e-47 1.5e-45
2 TCGA Bladder Urothelial Carcinoma 0.0940 0.0460 4.0e-04 0.045 0.029 0.029 NA 0.036 1.0e-04 1.5e-03 1.6e-03 NA 4.5e-04
3 TCGA Breast Invasive Carcinoma 0.0906 0.0431 1.8e-10 0.050 0.050 0.047 NA 0.046 1.8e-10 1.9e-10 6.3e-10 NA 9.2e-10
4 TCGA Cervical Squamous Cell Carcinoma 0.0710 0.0440 5.2e-03 0.004 0.050 0.041 NA 0.038 1.9e-01 1.8e-03 4.2e-03 NA 5.8e-03
5 TCGA Colon Adenocarcinoma 0.0920 0.0600 3.2e-03 0.033 0.026 0.020 NA 0.033 5.1e-03 1.2e-02 2.4e-02 NA 4.9e-03
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0700 0.0416 5.5e-03 0.009 0.017 0.028 NA 0.020 3.0e-02 4.3e-03 3.8e-04 NA 2.3e-03
7 TCGA Kidney Renal Clear Cell Carcinoma 0.1381 0.0626 1.2e-08 0.049 0.078 0.078 NA 0.065 2.8e-06 4.0e-09 3.9e-09 NA 7.5e-08
8 TCGA Liver Hepatocellular Carcinoma 0.1430 0.0670 1.8e-05 0.149 0.100 0.125 NA 0.141 1.7e-07 2.0e-05 1.8e-06 NA 3.9e-07
9 TCGA Lung Adenocarcinoma 0.0736 0.0450 3.9e-03 0.018 0.023 0.014 NA 0.019 2.9e-03 9.5e-04 7.1e-03 NA 2.4e-03
10 TCGA Lung Squamous Cell Carcinoma 0.1626 0.0764 2.2e-06 0.042 0.018 0.025 NA 0.029 1.3e-05 3.7e-03 6.4e-04 NA 2.7e-04
11 TCGA Pancreatic Adenocarcinoma 0.2230 0.0960 1.9e-04 0.021 0.081 0.079 NA 0.025 4.2e-02 2.7e-04 3.2e-04 NA 3.2e-02
12 TCGA Prostate Adenocarcinoma 0.1168 0.0540 2.1e-06 0.034 0.067 0.072 NA 0.060 1.5e-04 1.7e-07 5.0e-08 NA 6.2e-07
13 TCGA Soft Tissue Sarcoma 0.1290 0.0700 4.2e-03 -0.004 0.021 0.041 NA 0.002 6.2e-01 2.0e-02 1.7e-03 NA 2.3e-01
14 TCGA Thyroid Carcinoma 0.4140 0.1300 0.0e+00 0.269 0.253 0.305 NA 0.280 3.2e-26 1.6e-24 3.8e-30 NA 2.0e-27

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.6 1.4 -1.0 0.3 -0.7 -0.3 -1.1 0.0 -0.9 1.2 -0.4 0.0 -0.8 -1.1 -1.0 -0.7
Bipolar Disorder or Schizophrenia 1.8 4.3 9.7 -2.2 -0.3 -2.3 -1.6 -3.1 0.0 -2.3 2.5 -1.9 0.0 -2.2 -2.9 -2.5 -1.8
Depressed Affect (Nagel 2018) 0.6 1.3 4.0 1.0 -1.3 1.0 -0.6 -0.1 -1.0 0.8 -0.7 -1.9 -1.3 1.4 0.4 2.0 0.3
Depression (Nagel 2018) 1.3 2.0 5.3 -1.0 -1.0 -0.9 -1.1 -2.1 -1.2 -1.4 1.1 -2.3 -1.5 -1.1 -1.9 -0.2 -1.5
Intelligence (Savage-Jansen 2018) 2.1 6.4 12.5 -3.5 2.3 -2.8 -1.5 -2.8 0.5 -2.8 3.4 0.3 1.4 -2.4 -3.0 -2.9 -3.1
Neuroticism (Nagel 2018) 0.1 0.3 1.7 0.2 -0.5 0.2 -0.6 -0.6 -0.6 0.1 0.2 -1.3 -0.7 0.5 -0.3 0.9 -0.3
Schizophrenia (2018) 2.0 4.2 9.5 -2.0 -0.6 -2.4 -1.8 -3.1 0.0 -2.2 2.2 -2.2 0.0 -2.1 -2.8 -2.5 -1.8
Schizophrenia vs Biploar Disorder 0.6 0.8 3.2 0.6 0.6 1.0 0.1 0.4 0.0 1.5 0.2 -0.1 0.0 1.8 1.0 1.4 0.9
Worry (Nagel 2018) 0.2 0.4 1.0 0.7 0.2 0.6 1.0 0.7 0.7 0.4 -0.3 0.9 0.4 0.1 0.6 0.2 0.6
Alzheimer’s Disease (in mother) 0.3 0.3 1.4 -0.3 1.2 0.2 -0.1 -0.1 0.8 0.4 0.8 0.4 1.1 0.7 0.1 0.3 -0.1
Alzheimer’s Disease (in father) 0.4 0.4 1.3 0.2 1.1 0.2 -0.5 -0.3 0.7 0.3 0.9 -0.1 1.0 0.9 -0.1 1.0 -0.2
Alzheimer’s Disease (including proxy) 1.1 1.6 6.2 -0.4 2.5 0.6 0.1 -0.0 1.8 1.0 1.6 0.9 2.3 1.5 0.4 1.0 -0.0
Crohns Disease (2017) 0.9 1.9 4.1 0.5 1.3 1.5 1.4 1.6 2.0 1.2 -0.3 1.8 1.6 1.1 1.6 1.1 1.0
Irritable Bowel Disease (IBD) 0.7 1.6 3.6 1.1 -0.5 1.5 1.3 1.9 0.8 1.2 -1.6 1.0 0.1 0.7 1.8 1.0 1.6
Ulcerative Colitis (UC) 0.4 0.8 2.9 0.8 -1.2 0.8 0.8 1.3 -0.3 0.7 -1.7 0.4 -0.8 0.0 1.1 0.1 1.1
Major Depression (MDD) 0.9 1.1 2.7 1.6 0.3 1.4 1.1 -0.1 0.0 1.5 0.9 -0.5 0.0 1.4 0.8 1.0 1.6
Reaction Time 0.3 0.6 1.6 0.4 0.9 0.3 0.7 0.8 0.5 1.1 0.1 1.3 1.0 0.7 1.0 -0.3 0.4
Verbal and Numeric Reasoning (VNR) 2.0 4.7 9.6 -3.1 1.9 -2.3 -0.9 -2.1 1.0 -2.8 2.4 0.7 1.3 -2.5 -2.6 -2.5 -2.6
Breast Cancer 0.4 0.9 2.4 -1.5 1.2 -1.0 -0.5 -0.9 0.2 -0.6 1.6 0.3 0.8 -0.6 -0.8 -1.2 -1.0
Ovarian Cancer 0.3 0.5 0.9 -0.5 -0.7 -0.5 -0.2 -0.8 -0.6 -0.9 0.2 -0.8 -0.9 -0.9 -0.9 -0.7 -0.3
Prostate Cancer 0.8 1.2 3.2 -1.8 0.7 -1.5 -0.9 -0.3 0.2 -1.3 0.4 0.7 0.7 -1.0 -0.9 -1.2 -1.8
Age at First Birth 0.4 0.6 2.2 -0.4 -0.7 -1.0 -1.3 -0.6 -1.5 -0.0 0.3 -1.0 -0.8 -0.0 -0.4 -0.7 -0.6
Bipolar Disorder (2011) 0.5 0.5 1.4 -0.4 0.1 -0.7 -0.9 -1.2 0.0 0.0 1.1 -1.1 0.0 -0.1 -0.9 0.0 -0.5
Body Mass Index (BMI) (2010) 1.6 2.2 5.6 1.8 -1.1 1.7 1.2 2.1 0.4 1.2 -2.4 0.6 -0.4 1.1 1.9 1.7 1.6
Coronary Artery Disease (CAD) 1.0 1.2 2.3 1.5 0.7 1.4 1.1 1.0 0.0 1.5 0.1 0.5 0.0 1.5 1.4 1.4 1.3
Crohns Disease (2012) 0.3 0.5 1.5 -1.2 0.8 -0.7 -0.6 -0.7 0.0 -0.8 1.1 0.1 0.0 -0.4 -0.7 -0.6 -0.9
Mean Putamen Volume 0.3 0.3 1.8 0.1 -0.6 0.6 1.4 0.4 0.0 -0.3 -0.6 0.4 0.0 -0.8 0.1 -0.3 0.7
Fasting Glucose 0.6 0.7 1.8 1.3 -1.3 0.8 1.0 0.3 -0.2 0.3 -1.0 -0.4 -1.2 -0.4 0.4 0.1 1.4
HbA1C 1.3 1.5 4.9 -0.9 -0.9 -0.9 -1.9 -1.6 -1.4 -0.9 0.6 -2.2 -1.3 -0.2 -1.4 0.2 -0.8
HDL Cholesterol 0.6 1.0 5.7 0.4 1.8 0.6 1.2 1.4 0.0 0.2 -0.2 2.4 0.0 0.2 0.9 0.4 0.0
LDL Cholesterol 0.1 0.2 0.8 -0.6 0.7 -0.3 -0.3 -0.5 0.0 -0.1 0.9 0.0 0.0 0.1 -0.3 -0.2 -0.4
Lupus 0.7 1.0 4.9 -0.1 -2.2 -0.7 -0.4 -0.2 0.0 -1.2 -1.7 -0.9 0.0 -1.5 -0.7 -1.0 -0.3
Neuroticism (2016) 1.3 1.9 3.2 -1.4 -1.7 -1.4 -1.3 -1.5 0.0 -1.8 0.3 -1.8 0.0 -1.6 -1.7 -1.5 -1.1
Primary Biliary Cirrhosis 0.5 0.7 2.1 -0.7 0.0 -0.8 -0.6 -1.5 0.0 -0.6 0.8 -1.4 0.0 -0.8 -1.1 -1.0 -0.3
Rheumatoid Arthritis 1.1 1.6 8.0 -0.1 1.9 1.1 2.3 1.4 0.0 0.3 0.1 2.8 0.0 -0.1 1.1 0.2 0.6
Schizophrenia (2014) 1.1 2.4 6.8 -1.8 -0.3 -1.5 -1.4 -2.6 0.0 -1.1 2.3 -2.1 0.0 -0.9 -2.0 -1.5 -1.1
Triglycerides 0.0 0.1 0.5 0.2 -0.6 0.0 0.0 0.2 0.0 -0.1 -0.7 -0.1 0.0 -0.2 0.0 -0.0 0.1
Type 2 Diabetes (T2D) (2012) 1.1 1.3 5.2 0.1 2.3 1.0 1.9 1.0 0.0 0.5 0.7 2.3 0.0 0.4 0.9 0.4 0.5
Ulcerative Colitis 0.1 0.2 0.8 -0.5 -0.9 -0.1 0.4 -0.1 0.0 -0.6 -0.5 -0.1 0.0 -0.9 -0.3 -0.6 0.1
Blood Eosinophil Count 1.3 10.4 20.6 3.8 -0.7 4.1 4.5 4.0 1.6 3.6 -3.0 2.4 0.3 2.2 4.2 2.4 4.4
Blood Platelet Count 0.5 5.2 17.1 0.4 -3.4 -0.8 -0.3 -2.4 -3.9 -0.7 0.2 -3.5 -4.1 -1.8 -1.6 -2.0 0.8
Blood Red Count 0.4 3.8 7.6 2.4 -0.3 2.4 1.5 2.1 0.5 2.8 -1.5 0.5 0.2 2.5 2.5 2.4 2.4
Blood White Count 0.3 2.3 7.3 0.3 -2.2 -0.4 -0.8 -1.6 -2.6 -0.3 0.2 -2.6 -2.7 -0.7 -1.0 -0.8 0.5
Heel T-Score 0.0 0.1 0.6 0.8 -0.2 0.2 -0.1 -0.0 -0.1 -0.1 -0.0 -0.4 -0.2 0.1 0.0 0.5 0.1
BMI 0.4 2.4 7.4 1.7 -0.8 1.6 -0.2 1.6 -0.1 1.8 -1.8 -0.5 -0.3 2.3 1.8 2.7 1.3
Height 0.0 0.6 1.8 -1.3 0.7 -0.6 -0.7 0.2 0.9 -1.0 -0.2 0.7 0.8 -0.5 -0.4 0.0 -1.1
Waist Hip Ratio (WHR) 2.1 9.4 27.2 3.6 -0.1 2.3 3.5 5.2 2.8 1.4 -4.6 4.8 1.7 0.4 3.7 1.1 1.6
Systolic Blood Pressure 1.7 8.6 19.6 4.1 0.3 2.6 1.9 4.4 1.6 3.4 -3.2 2.9 1.6 3.1 4.2 2.5 2.2
Smoking Status 0.3 0.7 2.4 -0.5 1.6 -0.4 -0.0 -0.3 1.2 -0.5 1.1 0.9 1.4 -0.4 -0.5 -0.5 -0.8
Allergy or Eczema 3.8 9.9 19.8 3.4 0.7 3.5 3.0 4.5 3.2 2.9 -3.2 3.2 2.0 2.6 4.0 3.5 2.6
Cardiovascular Disease 0.3 1.1 4.9 0.9 -1.1 1.0 0.3 1.7 0.3 0.6 -2.2 0.4 -0.4 0.6 1.2 1.4 0.8
Hypothyroidism (self reported) 0.4 0.9 2.1 -0.5 -1.5 -1.1 -1.3 -0.2 -1.5 -0.6 -1.0 -0.8 -1.3 -0.8 -0.5 -0.9 -0.8
Respiratory disease 1.7 3.8 8.2 2.8 -1.9 2.3 2.9 2.3 0.3 1.2 -2.7 1.0 -1.1 0.2 2.0 1.0 2.5
Type 2 Diabetes (T2D) (2018) 1.8 3.3 7.3 2.7 -0.8 2.1 0.9 2.0 0.2 2.2 -2.0 0.1 -0.2 2.2 2.2 2.5 2.1
Lung FEV1/FVC ratio 2.3 11.7 23.2 4.8 -2.2 3.7 2.2 4.3 -0.0 4.0 -4.6 0.9 -0.8 3.5 4.4 3.7 3.8
Lung FVC 3.7 18.9 43.7 -6.6 2.7 -4.5 -5.1 -6.3 -1.6 -3.3 6.6 -3.4 0.6 -1.6 -5.3 -2.8 -4.5
Neuroticism 0.2 0.6 1.4 -1.2 0.1 -0.4 -0.9 -1.2 -0.0 -0.8 0.7 -1.1 -0.2 -0.2 -1.1 0.4 -0.6
Chronotype (morning person) 0.8 1.8 4.7 2.1 -0.2 1.8 2.2 1.4 1.1 0.8 -1.2 0.9 0.2 0.5 1.3 1.3 1.6
Hair Pigment 0.0 0.9 2.1 -1.2 -0.8 -0.7 -0.0 -1.2 -1.0 -0.5 0.3 -0.7 -1.1 -1.1 -1.1 -1.4 -0.2
Tanning 0.1 1.4 4.3 0.6 0.8 0.6 0.5 1.9 1.7 0.6 -1.4 2.1 1.5 0.7 1.3 0.9 -0.1
Hand grip strength (left) 0.3 0.9 2.6 -0.8 -1.2 -0.6 -1.3 -0.8 -1.2 -0.8 -0.4 -1.6 -1.3 -0.4 -0.9 0.2 -0.6
Number of treatments/medications taken 4.2 7.5 15.8 3.6 -1.2 3.6 1.5 1.8 -0.3 3.8 -1.4 -1.2 -0.9 3.9 3.0 4.0 3.8
Average weekly spirits intake 0.8 1.0 2.2 0.9 -0.1 1.3 1.0 1.1 0.4 1.5 -0.6 0.5 0.2 1.2 1.4 1.0 1.3
Sensitivity / hurt feelings 0.2 0.4 1.6 0.2 0.9 0.7 0.0 0.0 0.9 0.2 0.5 0.0 0.8 0.8 0.1 1.2 0.2
Frequency of depressed mood in last 2 weeks 1.5 2.1 5.1 -0.8 -1.4 -1.3 -2.0 -1.7 -1.8 -1.3 0.2 -2.3 -1.7 -0.9 -1.6 -0.5 -1.0
Hearing difficulty/problems: Yes 1.7 2.6 6.9 1.7 -1.2 2.0 2.3 2.2 1.0 0.7 -2.6 1.1 -0.4 0.1 1.7 1.3 1.9
Relative age of first facial hair 0.8 1.7 5.4 -0.9 0.5 -0.8 -0.3 -2.3 -0.1 -1.5 2.2 -1.2 -0.3 -1.4 -2.0 -1.0 -0.7
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 2.2 0.2 -1.5 -0.7 -0.2 -0.3 -1.3 -0.8 -0.8 -0.6 -1.4 -1.2 -0.6 -1.2 -0.2
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.3 -0.5 0.9 0.2 0.0 0.0 1.1 -0.3 0.4 0.5 0.9 0.1 -0.1 0.6 -0.3
Ever had hysterectomy (womb removed) 0.8 0.9 2.6 -1.3 -0.1 -1.1 -0.9 -0.7 -0.1 -1.6 0.1 -0.2 -0.2 -1.3 -1.2 -0.8 -1.3
Systolic blood pressure, automated reading 2.2 6.5 13.2 3.5 1.0 2.4 1.1 3.3 1.3 3.5 -1.7 1.9 1.8 3.6 3.5 2.6 1.9
Eye problems/disorders: Diabetes related eye disease 2.2 2.4 6.0 1.9 -2.4 1.4 0.6 0.8 -1.4 1.3 -1.8 -1.5 -2.1 0.9 1.1 1.4 2.0
Angina 0.3 0.4 0.9 1.0 -0.9 0.5 0.4 0.5 -0.8 0.8 -0.5 -0.3 -0.8 0.4 0.7 0.0 0.9
Medication for hormone replacement therapy 0.9 1.0 3.3 1.1 -0.5 0.8 -0.7 -0.3 -0.5 1.0 0.1 -1.6 -0.6 1.5 0.3 1.8 0.8
Vitamin and mineral supplements 0.5 0.6 1.4 -0.9 -0.4 -1.2 -0.9 -0.3 -0.7 -0.9 -0.1 0.0 -0.3 -0.9 -0.7 -1.2 -1.1
Supplements: Zinc 1.1 1.2 4.2 0.5 0.6 1.4 1.3 -1.1 0.1 1.3 2.1 -1.1 -0.1 1.0 0.1 0.8 1.7
Medication: Co-codamol 0.8 0.9 2.6 1.6 -1.1 1.1 0.9 1.0 -0.2 0.8 -1.4 -0.0 -0.7 0.4 1.0 0.7 1.3
Medication: Metformin 1.0 1.4 3.0 1.4 -0.3 1.7 1.0 1.0 0.3 1.6 -0.8 -0.2 -0.1 1.5 1.4 1.7 1.7
Diabetes (father) 0.4 0.4 1.6 0.4 -0.2 0.6 -0.2 0.6 -0.2 1.0 -0.4 -0.3 -0.1 1.2 0.8 1.1 0.6
Diabetes (mother) 1.5 2.0 4.4 2.1 -0.6 1.9 0.9 0.9 0.1 1.7 -0.9 -0.6 -0.4 1.7 1.4 2.1 2.0
Severe depression (siblings) 0.5 0.6 1.9 0.5 0.3 0.4 0.7 1.1 1.4 -0.4 -1.1 1.4 0.7 -0.5 0.4 0.3 -0.1
Pack years adult smoking proportion 0.2 0.4 1.5 0.5 -0.9 -0.4 -0.3 -0.1 -1.2 0.2 -0.3 -0.5 -1.0 -0.3 0.0 -0.9 0.2
Impedance of leg (right) 0.2 1.1 4.2 -0.5 0.8 -0.5 1.3 -0.5 0.7 -0.9 1.1 1.3 0.5 -1.7 -0.7 -2.0 -0.3
Leg fat-free mass (left) 0.2 1.0 4.3 0.2 -1.1 0.3 -1.4 0.7 -0.4 0.2 -1.7 -1.1 -0.7 1.1 0.4 2.1 -0.0
Trunk fat percentage 0.4 1.6 5.6 1.5 -0.2 1.5 0.1 1.1 0.4 1.5 -0.9 -0.4 0.1 2.0 1.4 2.4 1.3
Hand grip strength (right) 0.1 0.3 1.5 -1.2 0.2 -0.6 -0.8 -0.1 0.0 -0.5 0.0 0.0 0.2 -0.2 -0.4 -0.1 -0.8
Townsend deprivation index at recruitment 2.0 2.8 5.3 -1.3 -2.2 -1.6 -1.3 -1.2 -2.0 -1.9 -0.7 -1.6 -2.3 -2.2 -1.7 -1.5 -1.1
Current tobacco smoking 0.6 0.9 2.1 -0.9 -0.4 -0.9 -1.0 -1.4 -0.9 -0.9 0.7 -1.4 -0.8 -0.8 -1.3 -0.7 -0.7
Average weekly fortified wine intake 1.0 1.2 2.9 1.7 -1.3 0.9 0.3 0.9 -0.8 1.2 -1.4 -0.6 -1.0 0.9 1.1 0.9 1.3
Maternal smoking around birth 0.3 0.5 1.8 0.1 -0.5 0.2 0.9 0.9 0.5 -0.8 -1.3 1.0 -0.1 -1.1 0.2 -0.5 0.0
Fed-up feelings 0.7 1.3 4.6 -0.6 -1.6 -0.5 -1.4 -1.1 -1.6 -0.6 -0.3 -2.1 -1.8 -0.3 -0.9 0.3 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.9 -1.2 -0.9 -0.9 -0.5 -1.4 -0.8 -1.6 0.4 -1.1 -1.2 -1.7 -1.6 -1.0 -0.8
Relative age voice broke 0.3 0.4 1.4 -0.6 0.4 -0.1 0.5 -0.8 0.7 -1.1 0.8 0.0 0.1 -1.2 -0.9 -0.5 -0.2
Taking other prescription medications 1.7 2.6 5.3 2.0 -1.3 2.0 0.8 1.6 -0.2 1.9 -1.9 -0.4 -0.8 1.8 1.9 2.3 2.0
Age when periods started (menarche) 0.2 0.4 1.3 -0.3 -0.6 0.6 0.8 -0.8 -0.5 0.2 0.5 -1.2 -1.0 0.0 -0.3 0.4 0.9
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.7 0.3 -0.2 0.2 0.0 -0.0 0.8 -0.8 -0.5 -0.1 -0.0 -0.6 -0.4 0.7 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.0 -0.4 0.6 -0.4 -1.0 -0.8 -0.1 -0.1 0.9 -0.7 0.3 0.5 -0.5 0.5 -0.6
Tinnitus: Yes, but not now, but have in the past 0.3 0.4 1.1 0.7 -0.3 1.0 1.1 0.1 0.3 0.4 -0.0 -0.2 -0.3 0.3 0.3 0.8 1.0
Qualifications: CSEs or equivalent 0.5 0.6 1.4 0.5 -1.2 0.7 1.0 0.8 -0.4 0.6 -1.2 -0.0 -0.9 -0.0 0.8 0.2 1.1
Serious illness, injury or assault to yourself 0.3 0.4 1.0 0.0 -0.8 -0.2 0.4 -0.6 -0.8 -0.4 0.1 -0.6 -1.0 -0.8 -0.5 -0.8 0.2
High blood pressure 0.4 1.1 3.1 1.5 -1.5 0.8 -0.0 1.1 -0.6 0.7 -1.8 -0.5 -1.0 0.7 1.0 1.2 0.9
Hayfever, allergic rhinitis or eczema 2.9 6.4 13.8 2.6 0.7 2.6 2.7 3.7 3.0 1.9 -2.7 3.2 1.9 1.5 3.1 2.2 1.9
Multivitamins +/- minerals 1.2 1.5 3.5 1.3 0.3 1.5 0.8 1.1 0.7 1.7 -0.6 0.2 0.5 1.8 1.5 1.9 1.4
Stomach or abdominal pain in last month 0.2 0.3 1.4 -0.0 -0.3 -0.1 0.8 -0.1 0.1 -0.6 -0.1 0.4 -0.4 -1.2 -0.3 -1.0 0.1
Supplements: Glucosamine 0.9 1.2 4.9 0.7 0.2 1.5 0.4 0.4 0.5 1.5 0.0 -0.6 0.2 1.9 0.9 2.2 1.3
Diverticular disease/diverticulitis (self-reported) 1.6 1.9 5.2 -2.3 1.7 -1.4 -1.4 -1.0 0.8 -1.4 1.5 0.5 1.4 -0.6 -1.3 -0.7 -2.0
Medication: Atenolol 0.1 0.1 0.5 0.4 -0.4 0.4 -0.1 0.4 0.1 0.0 -0.6 -0.2 -0.2 0.2 0.3 0.7 0.2
Medication: Levothyroxine sodium 0.2 0.3 0.7 -0.7 -0.3 -0.7 -0.7 0.6 -0.1 -0.3 -0.9 0.6 0.1 -0.3 0.2 -0.3 -0.7
Sitting height 0.1 0.7 3.2 -1.1 1.0 0.0 -0.1 -0.0 1.8 -1.2 0.3 0.7 1.1 -0.6 -0.6 0.7 -0.8
Chronic bronchitis/emphysema (father) 1.4 1.7 2.8 -1.6 -0.8 -1.5 -1.3 -1.3 -1.0 -1.7 0.4 -1.1 -1.0 -1.5 -1.6 -1.1 -1.4
High blood pressure (mother) 0.5 0.7 2.1 1.2 -1.0 -0.1 -0.8 0.4 -1.4 1.1 -0.8 -0.7 -0.8 0.9 0.8 0.0 0.5
Body mass index (BMI) 0.6 2.6 8.8 1.8 -0.7 1.7 -0.2 1.4 0.0 2.0 -1.5 -0.7 -0.2 2.5 1.8 3.0 1.5
Impedance of leg (left) 0.3 1.2 3.6 -0.3 0.9 -0.2 1.8 -0.1 1.1 -1.0 0.9 1.7 0.7 -1.8 -0.5 -1.9 -0.2
Leg predicted mass (left) 0.2 1.0 4.6 0.2 -1.1 0.4 -1.4 0.7 -0.3 0.3 -1.6 -1.1 -0.6 1.1 0.4 2.1 -0.0
Trunk fat mass 0.4 1.8 7.1 1.5 -0.6 1.5 -0.2 1.3 0.3 1.3 -1.5 -0.5 -0.1 1.9 1.4 2.7 1.1
Waist circumference 0.9 3.5 8.0 2.5 -1.3 1.9 0.6 2.5 0.2 1.7 -2.8 0.2 -0.4 1.9 2.3 2.7 1.7
Number of incorrect matches in round 1.1 1.7 6.6 0.1 2.6 0.6 1.0 -0.3 1.8 0.8 2.4 1.1 2.2 0.9 0.3 0.3 0.3
Past tobacco smoking 0.3 0.6 3.4 0.7 -1.3 -0.1 -0.0 1.0 -0.6 -0.0 -1.9 0.2 -0.8 -0.4 0.5 -0.3 0.1
Alcohol usually taken with meals 1.0 1.7 3.8 1.2 -0.1 1.9 1.8 1.1 0.7 1.7 -0.6 0.4 0.1 1.3 1.6 1.4 1.9
Nervous feelings 0.5 0.9 2.7 0.8 0.9 0.8 0.9 1.3 1.6 0.2 -0.7 1.5 1.3 0.4 0.9 0.8 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 2.1 0.7 -1.4 0.7 0.6 0.1 -0.4 -0.3 -0.8 -0.7 -1.3 -0.5 -0.0 0.5 0.7
Hearing difficulty/problems with background noise 0.5 0.8 2.0 1.2 -1.4 0.8 0.5 0.4 -1.0 0.7 -1.0 -0.8 -1.3 0.4 0.6 0.5 1.2
Hair/balding pattern: Pattern 2 0.8 1.0 2.1 1.1 -0.2 1.3 0.7 1.2 0.4 1.3 -1.0 0.3 0.2 1.3 1.3 1.5 1.1
Had menopause 0.5 0.7 2.7 -0.8 1.1 0.2 -0.5 -1.1 0.6 -0.0 1.6 -0.8 0.7 0.7 -0.6 0.9 -0.1
Had other major operations 0.4 0.5 1.7 0.4 0.5 1.0 1.3 0.3 1.0 0.6 0.1 0.5 0.5 0.3 0.5 0.6 1.0
Forced vital capacity (FVC) 2.2 8.3 19.8 -4.5 2.3 -3.1 -3.5 -3.6 0.2 -3.0 3.8 -1.4 1.3 -1.3 -3.6 -1.3 -3.8
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 2.1 0.7 -0.9 0.3 -0.3 -0.6 -0.8 0.2 -0.0 -1.4 -1.0 0.3 -0.3 0.8 0.4
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.4 0.5 -1.1 -0.0 0.3 -0.5 -0.8 -0.3 -0.0 -0.8 -1.2 -0.7 -0.4 -0.5 0.4
Qualifications: None of the above 0.6 1.2 3.8 0.9 -0.1 1.0 1.9 1.6 0.9 0.6 -1.2 1.7 0.4 -0.1 1.3 -0.1 1.1
Financial difficulties in last 2 years 0.9 1.2 2.3 -1.5 -0.6 -1.1 -1.0 -1.5 -1.1 -0.9 0.9 -1.3 -1.0 -1.0 -1.4 -1.0 -0.7
Mouth/teeth dental problems 0.4 0.6 1.7 0.9 -0.3 0.7 -0.1 0.3 -0.5 1.2 -0.4 -0.6 -0.3 1.3 0.7 0.9 0.9
Heart attack 0.5 0.6 1.7 0.9 0.2 0.9 0.5 0.6 0.0 1.3 0.2 0.1 0.3 1.3 1.0 0.8 1.0
Allergy 3.2 7.3 17.6 -3.1 0.0 -2.8 -2.9 -4.2 -2.5 -2.2 3.4 -3.2 -1.3 -1.5 -3.5 -2.1 -2.3
Pain all over the body in last month 0.2 0.3 1.1 -0.1 0.4 -0.2 -0.1 -0.9 0.3 -0.6 1.1 -0.3 0.1 -0.6 -0.8 -0.4 -0.2
Diabetes (self-reported) 1.3 2.0 4.2 2.0 -1.6 1.9 1.5 1.2 -0.1 1.0 -1.8 -0.4 -1.1 0.7 1.3 1.6 2.0
Hayfever/allergic rhinitis (self-reported) 2.0 2.6 5.6 1.9 1.2 1.5 2.0 2.0 2.0 1.3 -0.8 2.4 1.7 1.0 1.8 0.9 1.1
Medication: Ramipril 0.3 0.3 0.7 0.5 -0.3 0.7 0.8 0.8 0.3 0.6 -0.7 0.5 -0.0 0.2 0.8 0.4 0.7
Medication: Simvastatin 0.5 0.7 1.8 1.1 -0.6 1.1 1.2 0.8 0.3 0.8 -0.8 0.2 -0.4 0.3 0.9 0.7 1.4
Fluid intelligence score 1.3 2.6 5.7 -2.1 0.7 -1.9 -1.1 -1.7 0.2 -2.4 1.2 -0.1 0.2 -2.2 -2.2 -1.9 -2.0
Illnesses of siblings 0.7 1.0 2.5 -1.6 0.9 -1.0 -0.8 -1.4 0.2 -1.0 1.5 -0.4 0.5 -0.5 -1.4 -0.5 -1.2
Neuroticism score 0.3 0.6 1.6 -0.8 -0.7 -0.6 -0.8 -0.6 -0.3 -1.3 -0.2 -0.7 -0.7 -0.9 -1.0 -0.1 -0.8
Weight 0.4 1.9 8.7 1.2 -0.8 1.4 -0.6 1.2 0.2 1.2 -1.6 -0.8 -0.3 2.0 1.3 2.9 1.0
Impedance of arm (right) 0.3 1.4 5.0 -0.7 0.4 -1.4 -0.3 -1.6 -0.7 -1.1 1.7 -0.2 -0.1 -1.4 -1.4 -2.2 -1.0
Arm fat percentage (right) 0.5 2.0 6.5 1.9 -0.4 1.6 -0.1 0.9 -0.1 1.9 -0.8 -0.8 -0.2 2.4 1.5 2.5 1.5
Trunk fat-free mass 0.2 1.1 4.8 0.4 -1.2 0.6 -0.9 1.1 -0.0 0.2 -2.1 -0.7 -0.6 0.9 0.6 2.2 0.1
Hip circumference 0.3 1.4 4.7 0.6 -1.4 0.8 -1.0 0.1 -1.0 0.8 -1.0 -1.9 -1.3 1.4 0.4 2.2 0.8
Time employed in main current job 4.4 5.1 12.7 3.6 -1.3 2.9 2.0 1.9 -0.1 2.8 -1.8 -0.3 -0.8 2.3 2.6 2.5 3.3
Alcohol intake versus 10 years previously 2.4 3.6 10.1 2.5 -1.1 1.8 2.6 2.8 1.1 0.9 -3.2 2.0 -0.1 -0.0 2.1 1.0 1.7
Father’s age at death 1.7 2.3 4.5 -2.0 -0.6 -2.1 -2.0 -0.9 -1.0 -2.0 -0.2 -0.5 -0.7 -1.7 -1.6 -1.6 -2.1
Worrier / anxious feelings 0.8 1.4 5.3 1.6 -2.3 0.8 0.8 0.7 -0.8 -0.1 -2.0 -0.6 -1.9 -0.6 0.4 0.4 1.1
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.4 4.0 -0.9 -0.5 -1.3 -0.6 -1.1 -0.4 -1.9 0.5 -0.3 -0.7 -2.0 -1.5 -1.6 -1.2
Falls in the last year 0.8 1.1 3.7 0.7 0.2 1.7 1.4 -0.3 0.3 1.3 0.9 -0.8 -0.2 1.1 0.6 1.2 1.9
Hair/balding pattern: Pattern 3 0.2 0.3 1.4 0.5 -0.7 0.1 -0.6 -0.4 -0.7 0.3 -0.1 -1.2 -0.8 0.5 -0.1 0.7 0.3
Number of live births 0.6 0.9 1.7 -0.7 -0.6 -0.9 -1.0 -1.3 -0.9 -1.0 0.6 -1.2 -0.9 -0.9 -1.3 -0.7 -0.7
Forced expiratory volume in 1-second (FEV1) 0.8 2.7 6.9 -2.6 1.6 -1.7 -2.3 -2.0 0.0 -1.3 2.3 -0.9 1.0 -0.2 -1.9 -0.4 -2.1
Pulse rate 2.0 3.4 8.9 3.0 -2.6 2.0 1.5 1.0 -1.1 1.3 -2.1 -1.3 -2.2 0.7 1.3 1.5 2.6
Happiness 0.6 0.7 1.9 -1.4 -0.4 -0.7 -1.0 -1.1 -0.5 -1.0 0.4 -1.2 -0.6 -0.7 -1.2 -0.1 -0.7
Noisy workplace 1.7 2.1 5.7 1.9 -0.7 1.9 1.4 0.9 -0.3 2.1 -0.8 -0.5 -0.6 1.7 1.6 1.5 2.4
Qualifications: A levels/AS levels or equivalent 0.5 1.1 2.2 -1.3 -0.6 -1.0 -0.6 -1.5 -1.0 -1.0 0.6 -1.2 -1.0 -1.1 -1.4 -1.1 -0.6
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 2.0 0.4 -1.0 0.4 1.4 0.1 -0.1 -0.5 -0.7 0.1 -0.9 -1.2 -0.1 -0.7 0.8
Mouth/teeth dental problems: Dentures 0.1 0.2 1.0 0.2 -0.2 0.7 1.0 0.4 0.5 0.1 -0.3 0.3 -0.0 -0.1 0.4 0.4 0.7
Asthma 1.2 2.4 7.6 2.2 -1.6 1.5 1.6 2.3 0.2 0.9 -2.8 1.0 -0.7 0.4 1.8 1.0 1.5
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.7 0.3 -0.2 -0.2 -0.2 -0.8 -0.6 0.1 0.8 -0.7 -0.5 -0.0 -0.4 -0.2 0.1
Medication: Cholesterol lowering 0.5 0.8 1.8 0.8 0.2 0.9 1.2 1.3 0.5 1.2 -0.7 1.2 0.5 0.6 1.4 0.2 1.0
Depression (self-reported) 0.2 0.2 0.7 -0.5 0.7 -0.3 -0.3 -0.5 0.4 -0.4 0.9 0.1 0.6 -0.1 -0.5 -0.2 -0.5
Medication: Lansoprazole 0.5 0.6 2.0 -0.1 -1.2 0.2 0.9 -0.6 -0.8 -0.5 0.0 -0.8 -1.4 -1.0 -0.5 -0.7 0.7
Prospective memory result 0.3 0.4 1.1 -0.7 -0.6 -0.4 0.1 -0.7 -0.8 -0.4 0.2 -0.5 -0.8 -0.8 -0.6 -1.0 0.0
Lung cancer (father) 1.6 1.9 3.7 1.9 0.4 1.7 1.4 1.7 1.1 1.4 -1.0 1.2 0.8 1.4 1.7 1.4 1.4
Illnesses of mother 0.3 0.4 1.5 -0.7 0.1 -0.0 0.9 -0.2 0.7 -1.0 0.2 0.6 0.0 -1.2 -0.6 -0.6 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.2 3.9 10.3 -3.2 1.6 -2.2 -2.5 -2.3 0.0 -1.9 2.3 -0.8 0.9 -0.8 -2.3 -1.0 -2.7
Pulse wave Arterial Stiffness index 0.8 0.9 3.2 0.9 0.1 1.5 1.8 0.6 0.9 0.7 -0.2 0.4 0.1 0.4 0.9 0.9 1.5
Impedance of arm (left) 0.3 1.2 4.1 -0.7 0.8 -1.2 0.0 -1.4 -0.2 -0.9 1.7 0.1 0.2 -1.3 -1.2 -2.0 -0.9
Arm fat mass (right) 0.5 2.1 8.7 1.6 -0.5 1.6 -0.3 1.1 0.1 1.7 -1.2 -0.9 -0.1 2.4 1.4 2.9 1.3
Trunk predicted mass 0.2 1.1 5.0 0.4 -1.2 0.7 -0.9 1.1 -0.1 0.2 -2.1 -0.7 -0.6 0.9 0.6 2.2 0.2
Standing height 0.1 0.6 2.0 -1.1 -0.2 -0.5 -0.9 -0.1 0.6 -1.4 -0.6 -0.1 0.0 -0.8 -0.8 0.4 -1.1
Length of working week for main job 0.2 0.2 0.9 -0.2 -0.6 -0.1 0.4 0.5 -0.2 -0.1 -0.9 0.3 -0.4 -0.6 0.2 -0.4 0.1
Exposure to tobacco smoke at home 1.1 1.2 3.4 1.5 -1.4 0.9 1.2 1.4 -0.5 0.8 -1.8 0.5 -1.0 0.0 1.2 -0.0 1.3
Breastfed as a baby 1.7 2.0 4.5 -0.6 -1.5 -1.0 -0.6 -2.0 -2.1 -0.8 0.8 -2.0 -2.1 -1.3 -1.5 -1.6 -0.1
Tense / ‘highly strung’ 0.2 0.4 0.9 0.5 -0.4 0.8 0.9 0.9 0.7 0.1 -0.9 0.6 -0.0 -0.1 0.6 0.5 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 1.6 2.4 4.6 -0.8 -1.5 -1.6 -2.1 -1.5 -2.0 -1.6 0.0 -2.0 -1.8 -1.2 -1.8 -1.0 -1.4
Hair/balding pattern: Pattern 4 0.4 1.0 2.4 1.5 -0.3 0.8 0.9 1.5 -0.0 1.4 -1.1 0.9 0.1 0.9 1.6 0.3 1.0
Birth weight of first child 1.2 2.1 6.0 -1.4 -1.0 -1.7 -1.3 0.2 -0.2 -2.4 -1.8 0.4 -0.6 -2.3 -1.2 -1.3 -1.9
Peak expiratory flow (PEF) 0.5 1.1 4.2 1.1 0.1 0.6 -0.5 1.2 -0.3 1.7 -0.9 0.0 0.4 2.1 1.5 1.4 0.6
Pulse wave reflection index 1.2 1.5 3.1 -1.7 1.7 -0.9 0.4 -0.7 0.9 -0.8 1.8 1.2 1.3 -1.1 -0.8 -1.7 -1.0
Ever highly irritable/argumentative for 2 days 0.5 0.7 1.6 -0.4 -0.6 0.1 1.3 -1.0 -0.4 -0.4 0.9 -0.5 -1.0 -1.2 -0.7 -1.1 0.7
Loud music exposure frequency 2.1 2.3 5.2 -2.1 0.3 -1.4 -0.1 -1.9 -0.2 -1.8 1.8 -0.2 -0.3 -2.2 -1.9 -2.3 -1.1
Qualifications: O levels/GCSEs or equivalent 0.2 0.2 1.3 -0.1 0.7 0.4 0.5 -0.8 0.3 0.1 1.2 -0.2 0.3 0.1 -0.4 0.0 0.4
Mouth/teeth dental problems: Bleeding gums 2.0 2.6 4.6 -2.2 0.5 -1.9 -2.0 -1.9 -0.4 -2.0 1.6 -0.9 0.1 -1.3 -2.1 -1.2 -2.2
Blood clot in the leg (DVT) 2.1 2.7 5.8 1.9 -1.2 1.9 1.9 2.2 0.2 1.6 -2.4 0.8 -0.5 0.9 2.1 1.2 2.0
Medication: Paracetamol 0.2 0.3 1.0 1.0 -0.2 0.8 0.6 -0.2 -0.0 0.4 0.4 -0.6 -0.4 0.4 0.2 0.7 0.9
Headache pain in last month 0.9 1.6 3.2 -0.8 -1.5 -1.0 -1.1 -1.3 -1.6 -1.4 -0.1 -1.6 -1.8 -1.4 -1.4 -1.0 -0.6
Medication for cholesterol, blood pressure or diabetes 0.0 0.0 0.2 0.1 0.3 0.1 0.0 -0.4 0.1 0.1 0.4 -0.2 0.2 0.2 -0.1 0.1 0.2
Glaucoma (self-reported) 1.5 1.7 6.4 0.1 -2.5 -0.6 -0.7 -0.3 -2.3 -0.5 -1.3 -1.5 -2.4 -0.9 -0.4 -0.8 0.1
Gout (self-reported) 0.8 1.0 3.9 1.0 0.6 0.5 0.9 1.6 1.2 0.5 -1.0 2.0 1.1 0.2 1.2 -0.1 0.2
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 2.0 -0.8 -0.6 -1.1 -1.4 -0.3 -1.0 -0.4 -0.2 -0.5 -0.5 -0.3 -0.4 -0.8 -0.9
Medication: Amlodipine 2.0 2.8 10.2 0.6 -3.2 -0.6 0.2 -0.3 -2.6 -0.7 -1.6 -1.3 -3.1 -1.8 -0.4 -1.7 0.5
Medication: Ventolin 100micrograms inhaler 1.5 2.0 5.7 2.4 -0.3 1.7 2.1 1.6 0.9 1.3 -1.3 1.1 0.1 0.6 1.6 0.9 1.7
Birth weight 0.8 1.6 5.9 1.2 -2.3 0.2 -0.3 1.2 -1.7 0.6 -2.4 -0.6 -1.8 0.4 0.9 0.4 0.6
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.5 -0.2 0.9 0.8 1.2 0.5 1.0 0.8 0.5 0.9 0.9 0.4 0.7 0.2 0.8
High blood pressure (siblings) 0.4 0.6 2.2 0.1 -1.4 -0.4 -0.7 -0.0 -1.5 0.0 -0.8 -0.9 -1.4 -0.2 -0.0 -0.5 0.1
Forced vital capacity (FVC), Best measure 2.7 9.7 23.3 -4.8 2.4 -3.5 -3.8 -3.8 -0.1 -3.2 3.9 -1.3 1.3 -1.6 -3.8 -1.9 -4.1
Body fat percentage 0.4 1.6 5.2 1.6 -0.4 1.5 0.2 0.9 0.2 1.6 -0.8 -0.5 -0.1 1.9 1.3 2.3 1.4
Leg fat percentage (right) 0.2 0.8 2.5 1.1 -0.1 1.0 -0.1 0.5 0.0 1.3 -0.3 -0.5 -0.0 1.5 1.0 1.6 1.0
Arm fat-free mass (right) 0.3 1.5 7.5 0.5 -0.5 1.3 -0.3 1.6 0.8 0.7 -1.9 0.0 0.2 1.5 1.2 2.7 0.6
Exposure to tobacco smoke outside home 0.9 1.3 4.2 -0.6 -1.7 0.3 0.5 -1.3 -1.0 -1.0 0.3 -1.7 -2.0 -1.2 -1.1 -0.1 0.6
Comparative body size at age 10 1.0 2.8 9.8 1.2 -0.4 1.5 -0.9 1.6 -0.1 2.2 -1.6 -0.6 0.2 3.0 1.9 3.1 1.1
Number of full brothers 0.4 0.5 2.1 -0.6 1.1 -0.3 0.3 -0.7 0.6 -0.5 1.5 0.3 0.8 -0.3 -0.6 -0.4 -0.5
Worry too long after embarrassment 0.1 0.2 0.5 -0.2 -0.1 -0.1 0.3 -0.7 0.2 -0.6 0.5 -0.4 -0.3 -0.7 -0.7 -0.1 -0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.8 -1.7 1.3 -1.2 -0.7 -1.0 0.6 -1.1 1.6 0.5 1.0 -0.9 -1.1 -1.2 -1.4
Wheeze or whistling in the chest in last year 1.1 1.9 5.2 1.7 -2.3 1.2 0.8 0.5 -1.4 1.0 -1.6 -1.3 -2.1 0.5 0.8 0.8 1.8
Number of children fathered 1.2 1.3 3.6 1.5 0.0 0.9 1.9 1.6 0.6 1.1 -0.9 1.7 0.4 0.2 1.5 -0.3 1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 0.2 -0.0 0.5 -0.1 -0.1 0.2 -0.1 0.5 0.4 0.4 0.5 0.4 0.3 -0.4 -0.1
Age at first live birth 0.3 0.5 3.1 -0.3 -1.2 -0.2 -0.5 0.6 -0.2 -0.8 -1.8 -0.1 -0.8 -0.6 -0.1 0.3 -0.4
Pulse wave peak to peak time 1.1 1.2 4.4 -1.2 0.2 -1.7 -2.1 -0.8 -0.8 -1.0 0.4 -0.5 0.0 -0.5 -1.1 -0.9 -1.8
Health satisfaction 0.5 0.7 2.1 1.1 -0.9 1.1 1.0 0.3 -0.2 0.7 -0.6 -0.6 -0.9 0.4 0.6 0.8 1.4
Shortness of breath walking on level ground 0.4 0.5 1.7 0.8 -1.2 0.4 0.6 -0.5 -0.6 -0.1 -0.0 -0.9 -1.3 -0.5 -0.3 0.0 0.7
Qualifications: College or University degree 0.8 2.6 6.1 -2.5 0.9 -2.0 -2.1 -1.9 -0.4 -1.5 1.8 -0.8 0.4 -0.9 -2.0 -1.1 -2.2
Eye problems/disorders: None of the above 0.9 1.0 2.2 0.8 1.0 1.0 1.1 1.2 1.4 0.9 -0.3 1.5 1.3 0.8 1.2 0.6 0.6
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.5 0.8 -0.4 0.5 -0.2 0.6 -0.5 1.2 -0.5 -0.3 -0.2 1.2 0.9 0.9 0.6
Emphysema/chronic bronchitis 0.8 0.9 2.3 -0.7 -0.9 -0.8 -1.0 -1.3 -1.3 -0.8 0.4 -1.5 -1.2 -0.7 -1.1 -0.6 -0.5
Medication for pain relief, constipation, heartburn 0.6 1.1 3.2 -1.4 1.0 -1.3 -1.0 0.3 0.7 -1.0 -0.2 1.4 1.3 -0.7 -0.4 -0.9 -1.8
Neck or shoulder pain in last month 1.2 1.7 3.7 1.2 1.2 1.3 1.9 1.3 1.8 1.0 -0.1 1.9 1.5 0.6 1.3 0.4 1.1
Medication: Blood pressure 0.5 0.8 3.3 0.6 -1.8 -0.3 -0.5 0.1 -1.5 -0.2 -1.1 -1.0 -1.6 -0.4 -0.1 -0.2 0.1
Angina (self-reported) 0.2 0.2 0.8 0.7 -0.7 0.2 0.0 0.0 -0.9 0.5 0.0 -0.5 -0.7 0.3 0.3 -0.3 0.5
Migraine (self-reported) 1.7 2.1 5.8 -2.4 1.7 -1.2 -1.1 -0.4 1.7 -1.8 0.7 1.1 1.7 -1.1 -1.2 -0.5 -2.1
Medication: Ibuprofen 0.3 0.3 1.2 1.1 -0.1 0.6 0.9 -0.3 -0.2 0.7 0.6 -0.3 -0.3 0.3 0.2 0.0 1.0
Medication: Allopurinol 0.3 0.4 2.0 0.6 0.2 -0.1 0.3 1.1 0.6 -0.2 -0.9 1.4 0.6 -0.4 0.5 -0.5 -0.4
Medication: Omeprazole 0.9 1.1 2.3 1.2 -1.4 1.4 1.4 1.0 -0.1 0.4 -1.5 -0.1 -1.1 0.0 0.8 0.9 1.5
Medication: Seretide 50 evohaler 0.5 0.5 1.4 -1.1 0.2 -1.0 -1.1 -0.4 -0.0 -0.9 0.3 0.0 0.2 -0.6 -0.7 -0.6 -1.2
Mean time to correctly identify matches 0.5 0.9 2.3 1.0 0.7 1.0 1.1 0.8 0.5 1.5 0.3 0.8 0.8 1.1 1.2 0.3 1.1
Heart disease (mother) 0.7 0.9 3.5 -0.8 1.3 0.1 0.7 0.7 1.9 -0.5 0.1 1.7 1.5 -0.4 0.1 0.1 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 3.0 3.5 11.1 2.2 1.0 2.4 3.3 1.7 2.0 1.7 -0.1 2.1 1.3 1.0 2.0 1.0 2.2
Whole body fat mass 0.5 1.9 7.8 1.5 -0.5 1.6 -0.2 1.0 0.2 1.6 -1.1 -0.8 -0.1 2.2 1.4 2.8 1.3
Leg fat mass (right) 0.3 1.3 5.6 1.1 -0.4 1.3 -0.2 0.9 0.2 1.3 -1.0 -0.6 -0.1 1.9 1.2 2.4 1.1
Arm predicted mass (right) 0.2 1.2 6.2 0.5 -0.7 1.1 -0.4 1.3 0.6 0.4 -1.9 -0.2 -0.1 1.1 0.9 2.5 0.5
Pulse rate, automated reading 1.3 4.2 12.5 2.7 -3.5 1.6 1.8 1.7 -1.3 0.6 -3.5 -0.6 -2.8 -0.5 1.3 0.8 2.2
Alcohol intake frequency. 0.3 0.6 2.5 0.6 -1.4 0.3 0.2 -0.5 -1.1 0.0 -0.3 -1.3 -1.6 -0.3 -0.2 -0.0 0.8
Comparative height size at age 10 0.0 0.3 1.7 -0.4 0.4 0.2 -0.6 -0.1 0.7 -0.1 0.0 -0.4 0.4 0.5 -0.2 1.3 -0.2
Number of full sisters 0.7 0.8 3.4 1.8 -0.1 0.7 0.7 1.2 0.3 1.0 -1.0 0.7 0.2 0.7 1.2 0.5 0.8
Suffer from ‘nerves’ 0.0 0.0 0.2 -0.1 -0.4 -0.1 -0.1 0.0 -0.2 -0.2 -0.3 -0.1 -0.3 -0.2 -0.1 -0.1 -0.1
Overall health rating 1.6 3.5 8.6 2.9 -2.1 2.0 2.1 2.2 -0.0 1.2 -2.9 0.5 -1.3 0.4 1.9 1.2 2.3
Chest pain or discomfort 2.4 3.5 6.7 -2.3 0.9 -2.5 -1.4 -1.5 0.1 -2.5 1.3 0.4 0.5 -2.4 -2.2 -2.5 -2.6
Had major operations 3.9 4.6 7.7 -2.4 -0.5 -2.7 -2.8 -2.5 -1.7 -2.5 1.4 -1.8 -1.1 -1.9 -2.7 -2.0 -2.5
Age at last live birth 0.6 0.9 3.0 -0.3 -0.8 -1.0 -1.0 0.6 0.1 -1.6 -1.7 0.5 -0.3 -1.3 -0.5 -0.4 -1.3
Family relationship satisfaction 0.3 0.3 1.4 -0.5 -0.3 -0.2 -1.0 -0.7 -0.6 -0.1 0.3 -1.2 -0.5 0.3 -0.4 0.4 -0.1
Leg pain on walking 0.9 1.1 4.2 1.5 -1.0 1.6 1.8 -0.0 -0.2 0.8 -0.0 -0.7 -1.1 0.1 0.5 0.5 2.0
Qualifications: NVQ or HND or HNC or equivalent 2.7 3.3 8.5 2.9 -1.8 2.1 1.6 1.9 -0.3 1.6 -2.5 -0.1 -1.2 1.2 1.9 1.8 2.3
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.5 0.3 -1.0 -0.2 -0.1 -0.6 -1.6 0.4 0.4 -1.0 -1.2 -0.1 -0.2 -0.9 0.4
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 1.6 0.1 0.3 -0.3 -1.3 -0.0 -0.1 0.2 -0.0 -0.3 0.3 0.7 -0.0 0.6 -0.5
Medication: Aspirin 0.7 0.9 2.4 1.0 -0.3 0.7 -0.0 -0.7 -1.1 1.4 0.9 -1.6 -0.7 1.4 0.3 0.8 1.3
Supplements: Vitamin C 0.9 1.0 3.4 -0.4 -0.2 -0.5 -0.4 -1.9 -0.8 -0.9 1.5 -1.5 -0.9 -0.8 -1.4 -0.7 -0.2
Knee pain experienced in last month 1.0 1.6 4.4 2.1 -0.5 1.2 0.9 1.2 -0.4 1.9 -0.9 0.2 -0.2 1.5 1.7 0.9 1.5
Hypertension (Self-reported) 0.5 1.3 3.1 1.6 -1.7 1.0 0.0 1.0 -0.7 0.7 -1.8 -0.8 -1.2 0.8 0.9 1.4 1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.1 5.8 1.0 -0.5 1.6 2.4 0.5 0.3 0.8 -0.2 0.3 -0.5 0.0 0.8 0.3 1.9
Illnesses of father: Heart disease 0.4 0.5 1.6 0.9 0.1 0.9 0.6 0.1 -0.1 1.3 0.3 -0.3 -0.0 1.1 0.7 0.8 1.1
Illnesses of siblings: Diabetes 2.1 2.6 5.6 2.4 -1.0 2.0 2.0 2.0 0.2 1.7 -1.8 0.8 -0.4 1.0 2.0 1.0 2.2
Smoking status: Previous 0.2 0.3 0.9 -0.2 0.8 0.3 -0.1 -0.4 0.5 0.2 0.9 -0.2 0.6 0.7 -0.1 0.8 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.9 -0.3 0.3 0.4 0.7 1.2 1.2 -0.2 -1.2 1.4 0.7 -0.2 0.6 0.3 -0.0
Whole body fat-free mass 0.2 1.3 5.9 0.4 -1.2 0.7 -1.0 1.1 -0.1 0.3 -2.1 -0.9 -0.6 1.1 0.7 2.4 0.2
Leg fat-free mass (right) 0.2 1.1 5.2 0.4 -1.2 0.5 -1.2 0.8 -0.3 0.3 -1.9 -1.0 -0.7 1.1 0.5 2.3 0.1
Arm fat percentage (left) 0.5 1.9 6.4 1.7 -0.3 1.5 -0.1 0.9 0.1 1.9 -0.7 -0.8 -0.0 2.3 1.4 2.5 1.4
Average weekly red wine intake 1.4 2.1 5.0 -2.1 0.3 -1.9 -1.7 -1.1 -0.1 -2.1 0.8 -0.2 0.1 -1.6 -1.7 -1.2 -2.2
Handedness (chirality/laterality): Left-handed 0.3 0.4 1.2 -0.3 0.5 -0.5 -1.0 0.4 0.8 -0.7 -0.5 0.6 0.8 -0.1 -0.2 0.4 -1.1
Mood swings 0.4 0.8 2.4 0.1 -1.2 0.1 -1.4 -0.1 -0.8 -0.1 -0.9 -1.6 -1.0 0.6 -0.2 1.4 -0.1
Loneliness, isolation 0.5 0.7 2.4 0.1 -0.4 1.0 0.6 -1.0 -0.1 0.1 0.8 -1.6 -0.9 0.3 -0.4 1.1 1.1
Long-standing illness, disability or infirmity 0.4 0.6 1.7 0.9 -1.3 0.8 0.9 0.3 -0.5 0.2 -1.0 -0.4 -1.2 -0.2 0.4 0.3 1.1
Ever had bowel cancer screening 0.9 1.0 2.7 -1.1 0.3 -0.9 -0.7 -1.6 -0.1 -1.3 1.5 -0.9 -0.2 -1.0 -1.6 -0.7 -0.9
Diabetes diagnosed by doctor 1.6 2.7 5.7 2.2 -0.8 2.3 1.6 1.4 0.5 1.8 -1.3 -0.2 -0.4 1.6 1.7 2.2 2.4
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.5 -0.1 -0.3 -0.7 -0.7 -0.3 -0.3 -0.6 -0.3 -0.2 -0.3 -0.6 -0.5 -0.5 -0.6
Friendships satisfaction 0.2 0.2 1.0 -0.1 1.0 0.2 0.3 -0.2 0.6 0.5 0.8 0.3 0.8 0.5 0.1 0.1 0.2
Qualifications: nursing, teaching 5.4 8.3 15.2 -3.8 -0.8 -3.2 -3.4 -3.9 -2.6 -2.9 2.1 -3.3 -1.9 -2.2 -3.8 -2.1 -2.7
Commuting to job workplace: Walk 1.4 1.5 4.8 -0.8 -0.3 -0.8 0.2 -1.7 -0.0 -2.0 1.1 -0.7 -0.8 -2.2 -1.9 -1.3 -0.7
Eye problems/disorders: Cataract 0.5 0.5 1.4 0.7 -0.8 0.9 0.8 -0.2 -0.5 0.6 -0.1 -0.9 -0.9 0.5 0.3 0.8 1.2
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.5 0.3 -1.5 -0.4 0.2 0.4 -0.4 -1.2 -1.5 0.2 -1.1 -1.6 -0.3 -0.8 -0.3
Medication for cholesterol 1.3 1.9 7.2 -1.8 0.7 -1.1 1.1 -0.4 0.5 -1.5 0.7 1.6 0.5 -2.3 -0.9 -2.7 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 2.5 0.8 -1.6 0.2 -0.8 0.3 -1.1 0.3 -1.3 -1.2 -1.3 0.5 0.3 1.0 0.4
Back pain experienced in last month 0.9 1.3 4.0 -1.2 1.7 -0.1 0.6 0.6 2.0 -0.6 0.4 1.9 1.9 -0.4 0.1 -0.2 -0.8
Mineral and other dietary supplements 1.4 1.8 4.6 -0.9 -0.9 -1.8 -0.9 -0.8 -1.1 -1.9 -0.2 -0.2 -1.0 -2.1 -1.4 -2.1 -1.5
Breast cancer (self-reported) 2.1 2.5 5.8 1.2 1.7 1.3 1.0 1.5 1.3 2.4 0.2 1.7 1.9 2.2 2.0 0.9 1.2
Asthma (self-reported) 1.2 2.4 6.9 2.2 -1.6 1.5 1.8 2.2 0.1 1.0 -2.6 0.9 -0.8 0.3 1.8 0.9 1.7
Osteoporosis (self-reported) 1.1 1.4 4.7 -0.1 -2.0 -0.5 -0.6 -0.9 -1.8 -0.8 -0.6 -1.8 -2.2 -1.0 -0.9 -0.4 -0.0
Osteoarthritis (self-reported) 1.9 2.5 7.1 2.0 -0.1 1.8 0.7 1.9 1.0 1.6 -1.7 0.4 0.5 2.0 1.9 2.7 1.4
Medication: Aspirin 1.2 1.5 3.8 1.6 -0.5 1.3 0.4 -0.2 -1.0 1.9 0.4 -1.4 -0.8 1.8 0.9 1.2 1.8
Medication: Gliclazide 0.2 0.3 0.7 -0.4 -0.6 -0.2 -0.2 -0.6 -0.7 -0.3 0.2 -0.8 -0.8 -0.4 -0.5 -0.4 0.1
Illnesses of father: None of the above (group 1) 0.8 1.0 3.8 -0.2 0.9 0.4 0.9 1.3 1.9 -0.4 -0.9 1.9 1.3 -0.4 0.5 0.2 -0.2
Smoking status: Current 0.6 0.9 2.0 -0.8 -0.1 -1.0 -1.2 -1.4 -0.9 -0.8 1.0 -1.2 -0.6 -0.6 -1.2 -0.8 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 2.9 6.2 -2.5 1.4 -1.9 -2.5 -2.1 -0.5 -1.2 2.4 -1.1 0.7 -0.2 -1.9 -0.8 -2.2
Whole body water mass 0.2 1.3 6.5 0.5 -1.2 0.8 -1.0 1.1 -0.0 0.4 -2.1 -0.8 -0.6 1.3 0.8 2.5 0.3
Leg predicted mass (right) 0.2 1.1 5.0 0.3 -1.2 0.5 -1.2 0.8 -0.3 0.3 -1.8 -1.0 -0.7 1.1 0.5 2.2 0.1
Arm fat mass (left) 0.5 2.0 8.5 1.5 -0.3 1.5 -0.4 1.2 0.3 1.7 -1.1 -0.7 0.1 2.4 1.5 2.9 1.2
Number of self-reported non-cancer illnesses 1.4 2.3 5.2 2.3 -0.8 1.8 1.5 2.0 0.2 1.7 -1.8 0.7 -0.2 1.3 2.0 1.3 1.9
Average weekly champagne plus white wine intake 0.3 0.5 1.9 -1.0 -0.0 -0.6 -0.1 -0.9 -0.9 -0.2 1.0 -0.3 -0.4 -0.5 -0.5 -1.4 -0.2
Miserableness 0.6 1.1 4.6 0.7 -2.1 -0.1 -0.6 0.3 -1.2 -0.6 -1.8 -1.0 -1.8 -0.5 -0.1 0.3 0.0
Guilty feelings 1.7 2.5 4.3 -1.4 -1.6 -1.8 -1.7 -1.2 -1.6 -2.1 -0.5 -1.3 -1.7 -2.0 -1.8 -1.6 -1.5
Wears glasses or contact lenses 0.4 0.4 1.0 0.2 0.5 0.6 0.3 0.8 1.0 0.5 -0.6 0.7 0.7 0.6 0.7 0.8 0.4
Ever taken oral contraceptive pill 1.5 1.7 5.8 -0.7 1.9 0.3 0.7 1.3 2.4 -0.1 -0.3 2.4 2.3 0.1 0.7 0.4 -0.6
Hearing aid user 0.4 0.4 1.3 0.2 0.6 0.8 0.6 0.2 0.3 1.1 0.3 0.1 0.5 1.0 0.7 0.6 0.9
Mother’s age at death 3.4 4.2 9.5 -0.2 -2.9 -1.6 -2.4 -1.7 -3.0 -1.8 -1.0 -3.1 -3.1 -1.4 -1.9 -0.7 -1.1
Financial situation satisfaction 0.5 0.7 2.0 -1.4 0.1 -0.8 -0.1 -0.6 0.2 -1.2 0.3 0.2 -0.0 -1.4 -1.0 -0.9 -0.9
Tinnitus: Yes, now most or all of the time 1.4 1.6 5.4 -0.0 2.3 0.3 0.3 0.8 1.4 1.3 0.9 1.7 2.3 1.5 1.1 0.2 -0.0
Commuting to job workplace: Public transport 0.5 0.6 1.8 1.1 -0.7 1.0 0.5 0.6 0.1 0.3 -1.0 -0.4 -0.5 0.5 0.5 1.3 0.8
Eye problems/disorders: Glaucoma 3.1 3.6 12.1 -0.0 -3.3 -0.7 -1.4 -1.2 -3.2 -0.7 -1.1 -3.1 -3.5 -0.8 -1.1 -0.4 0.2
Medication: Blood pressure 0.7 1.4 4.9 1.6 -0.4 1.2 -0.2 1.4 0.4 1.1 -1.5 -0.1 0.1 1.6 1.3 2.2 0.8
Pain type(s) experienced in last month: Hip pain 0.2 0.2 0.8 -0.3 0.9 0.1 0.1 -0.0 0.8 0.0 0.6 0.4 0.8 0.3 0.0 0.2 -0.1
Supplements: Fish oil (including cod liver oil) 2.0 2.6 6.7 1.3 1.1 2.0 1.1 1.0 1.0 2.5 0.4 0.4 1.2 2.6 1.8 2.1 1.8
High cholesterol (Self-reported) 0.1 0.1 0.5 0.2 0.5 0.2 -0.3 0.2 0.3 0.5 0.2 0.1 0.5 0.7 0.3 0.5 0.0
Medication: Bendroflumethiazide 0.4 0.6 3.3 0.8 -0.1 0.8 -0.4 0.9 0.5 0.5 -0.8 -0.1 0.3 1.2 0.7 1.8 0.3
Medication: Paracetamol 0.5 0.8 1.7 1.3 0.2 1.3 0.7 -0.0 0.3 1.0 0.5 -0.6 0.0 1.2 0.6 1.3 1.3
Medication: Lisinopril 0.6 0.8 2.3 0.8 0.8 0.8 -0.1 1.0 1.3 0.6 -0.5 0.6 1.1 1.1 0.8 1.5 0.3
Medication: Atorvastatin 1.0 1.3 3.4 1.7 -0.2 1.3 0.5 0.6 -0.4 1.8 -0.1 -0.4 -0.1 1.8 1.3 1.3 1.4
Illnesses of father: High blood pressure 0.6 0.8 2.5 1.1 -0.7 0.4 0.0 0.1 -1.6 1.6 0.2 -0.7 -0.8 1.1 0.9 -0.3 1.1
Alcohol drinker status: Never 0.8 1.0 4.0 -0.8 0.3 -0.7 -0.9 -1.8 -0.8 -0.2 2.0 -1.4 -0.3 -0.0 -1.1 -0.5 -0.4
Ever smoked 0.9 1.6 5.5 -1.5 1.0 -0.8 -0.4 -2.0 0.3 -1.3 2.3 -0.8 0.3 -1.0 -1.8 -0.7 -0.9
Basal metabolic rate 0.2 1.3 6.5 0.6 -1.1 0.8 -0.9 1.1 -0.0 0.5 -2.0 -0.8 -0.5 1.3 0.8 2.5 0.4
Leg fat percentage (left) 0.3 0.9 2.8 1.3 -0.2 1.2 0.1 0.9 0.2 1.2 -0.6 -0.2 0.1 1.5 1.1 1.7 1.0
Arm fat-free mass (left) 0.3 1.7 8.5 0.8 -0.6 1.4 -0.3 1.4 0.6 0.9 -1.8 -0.4 -0.0 1.7 1.2 2.9 0.8
Number of operations (self-reported) 0.6 0.9 1.8 -0.6 -0.8 -0.8 -0.8 -1.2 -0.8 -1.2 0.3 -1.2 -1.1 -1.1 -1.3 -0.6 -0.6
Average weekly beer plus cider intake 1.0 1.4 8.6 1.2 -1.7 0.1 0.3 1.6 0.0 -1.0 -2.9 0.8 -0.9 -1.2 0.4 -0.1 -0.1
Irritability 2.1 3.5 10.3 -2.4 -0.4 -2.2 -0.8 -1.1 -0.0 -3.1 0.2 0.3 -0.5 -3.2 -2.2 -2.4 -2.3
Risk taking 2.0 3.0 10.8 -1.5 -0.6 -2.3 -0.9 -1.4 -1.5 -2.0 0.6 -0.2 -1.0 -2.6 -1.8 -3.3 -1.7
Ever had prostate specific antigen (PSA) test 2.2 2.5 6.4 1.5 -0.0 1.4 2.5 2.4 1.6 0.8 -1.9 2.5 0.7 -0.0 1.8 0.4 1.2
Fractured/broken bones in last 5 years 1.0 1.2 3.7 -0.3 -1.6 -0.4 0.4 -1.1 -1.4 -0.8 -0.0 -1.2 -1.9 -1.6 -0.9 -1.4 0.4
Age started oral contraceptive pill 0.2 0.3 0.8 -0.0 0.8 0.3 -0.2 0.0 0.5 0.5 0.5 0.0 0.7 0.9 0.3 0.7 0.1
Diastolic blood pressure, automated reading 1.3 4.1 8.7 2.9 -0.5 1.8 0.9 2.9 0.2 2.7 -2.5 1.1 0.3 2.4 3.0 1.9 1.8
Ever depressed for a whole week 1.1 1.4 5.2 -0.6 -0.9 -0.6 1.3 -1.2 -0.7 -1.2 0.7 -0.3 -1.2 -2.3 -1.2 -2.1 0.1
Unable to work because of sickness or disability 0.3 0.3 2.2 -0.6 0.5 0.3 0.1 -0.8 -0.0 0.5 1.5 -0.6 0.1 0.6 -0.2 0.2 0.4
Commuting to job workplace: Cycle 0.7 0.9 2.0 -1.2 0.2 -1.3 -1.4 -1.1 -0.9 -0.6 0.9 -0.7 -0.1 -0.3 -1.0 -0.8 -1.2
Myopia 0.7 1.0 2.8 -1.2 0.6 -1.2 -0.4 -0.2 0.5 -1.2 0.2 1.0 0.6 -1.4 -0.7 -1.7 -1.2
Vascular/heart problems diagnosed by doctor 0.7 1.9 4.4 -2.1 1.0 -1.5 -0.6 -1.6 0.2 -1.6 1.7 -0.1 0.5 -1.5 -1.8 -1.6 -1.5
Cholesterol lowering medication 0.3 0.4 1.6 0.3 0.4 0.4 -0.3 -0.8 -0.2 0.6 1.3 -1.0 0.0 0.9 -0.1 0.8 0.5
Medication: Omeprazole (e.g. Zanprol) 1.1 1.4 3.9 1.5 -1.5 1.3 1.2 1.4 -0.0 0.5 -2.0 0.1 -1.0 0.1 1.1 1.0 1.4
Pain experienced in last month 0.6 1.0 3.3 -1.2 -0.0 -1.0 -1.8 -1.4 -0.9 -0.5 0.8 -1.5 -0.4 0.1 -1.1 -0.0 -1.0
Supplements: Calcium 0.6 0.7 2.0 1.1 -0.7 1.1 0.6 0.0 0.0 0.6 -0.4 -0.9 -0.7 0.6 0.3 1.4 1.2
Basal cell carcinoma (self-reported) 0.6 0.7 1.9 -0.6 1.4 -0.5 0.1 0.1 1.1 -0.4 0.6 1.3 1.4 -0.3 -0.1 -0.6 -0.8
Heart attack/myocardial infarction (self-reported) 0.5 0.6 1.7 0.9 0.0 0.9 0.5 0.7 -0.1 1.3 -0.0 0.1 0.1 1.2 1.1 0.7 1.0
Deep venous thrombosis (DVT) (self-reported) 2.0 2.6 4.9 1.9 -1.3 1.9 1.9 2.1 0.0 1.6 -2.2 0.7 -0.7 0.9 2.0 1.1 2.1
Heart disease (siblings) 0.3 0.4 0.6 0.8 0.8 0.7 0.6 0.4 0.8 0.5 0.4 0.5 0.8 0.6 0.5 0.6 0.4
Alcohol drinker status: Previous 0.3 0.3 0.9 -0.0 -1.0 -0.4 -0.7 0.1 -0.8 -0.3 -0.8 -0.4 -0.8 -0.3 -0.1 -0.3 -0.2
Pack years of smoking 0.2 0.3 0.9 0.7 -0.6 0.1 0.0 -0.1 -0.9 0.7 -0.1 -0.5 -0.7 0.2 0.3 -0.4 0.6
Impedance of whole body 0.3 1.3 4.7 -0.8 1.1 -0.9 0.7 -1.1 0.4 -1.1 1.7 0.8 0.6 -1.6 -1.1 -2.2 -0.8
Leg fat mass (left) 0.4 1.5 5.8 1.3 -0.4 1.5 -0.0 1.2 0.3 1.4 -1.1 -0.4 0.0 1.9 1.4 2.4 1.2
Arm predicted mass (left) 0.2 1.2 6.9 0.4 -0.6 1.0 -0.6 1.1 0.5 0.6 -1.6 -0.5 -0.0 1.4 0.9 2.6 0.4