Hub : Genes

CFHR3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.1720	0.0393	0.0e+00	0.301	0.294	0.306	0.307	0.300	1.1e-45	1.6e-44	1.2e-46	7.8e-47	1.5e-45
2	TCGA	Bladder Urothelial Carcinoma	0.0940	0.0460	4.0e-04	0.045	0.029	0.029	NA	0.036	1.0e-04	1.5e-03	1.6e-03	NA	4.5e-04
3	TCGA	Breast Invasive Carcinoma	0.0906	0.0431	1.8e-10	0.050	0.050	0.047	NA	0.046	1.8e-10	1.9e-10	6.3e-10	NA	9.2e-10
4	TCGA	Cervical Squamous Cell Carcinoma	0.0710	0.0440	5.2e-03	0.004	0.050	0.041	NA	0.038	1.9e-01	1.8e-03	4.2e-03	NA	5.8e-03
5	TCGA	Colon Adenocarcinoma	0.0920	0.0600	3.2e-03	0.033	0.026	0.020	NA	0.033	5.1e-03	1.2e-02	2.4e-02	NA	4.9e-03
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0700	0.0416	5.5e-03	0.009	0.017	0.028	NA	0.020	3.0e-02	4.3e-03	3.8e-04	NA	2.3e-03
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.1381	0.0626	1.2e-08	0.049	0.078	0.078	NA	0.065	2.8e-06	4.0e-09	3.9e-09	NA	7.5e-08
8	TCGA	Liver Hepatocellular Carcinoma	0.1430	0.0670	1.8e-05	0.149	0.100	0.125	NA	0.141	1.7e-07	2.0e-05	1.8e-06	NA	3.9e-07
9	TCGA	Lung Adenocarcinoma	0.0736	0.0450	3.9e-03	0.018	0.023	0.014	NA	0.019	2.9e-03	9.5e-04	7.1e-03	NA	2.4e-03
10	TCGA	Lung Squamous Cell Carcinoma	0.1626	0.0764	2.2e-06	0.042	0.018	0.025	NA	0.029	1.3e-05	3.7e-03	6.4e-04	NA	2.7e-04
11	TCGA	Pancreatic Adenocarcinoma	0.2230	0.0960	1.9e-04	0.021	0.081	0.079	NA	0.025	4.2e-02	2.7e-04	3.2e-04	NA	3.2e-02
12	TCGA	Prostate Adenocarcinoma	0.1168	0.0540	2.1e-06	0.034	0.067	0.072	NA	0.060	1.5e-04	1.7e-07	5.0e-08	NA	6.2e-07
13	TCGA	Soft Tissue Sarcoma	0.1290	0.0700	4.2e-03	-0.004	0.021	0.041	NA	0.002	6.2e-01	2.0e-02	1.7e-03	NA	2.3e-01
14	TCGA	Thyroid Carcinoma	0.4140	0.1300	0.0e+00	0.269	0.253	0.305	NA	0.280	3.2e-26	1.6e-24	3.8e-30	NA	2.0e-27

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.4	0.6	1.4	-1.0	0.3	-0.7	-0.3	-1.1	0.0	-0.9	1.2	-0.4	0.0	-0.8	-1.1	-1.0	-0.7
Bipolar Disorder or Schizophrenia	1.8	4.3	9.7	-2.2	-0.3	-2.3	-1.6	-3.1	0.0	-2.3	2.5	-1.9	0.0	-2.2	-2.9	-2.5	-1.8
Depressed Affect (Nagel 2018)	0.6	1.3	4.0	1.0	-1.3	1.0	-0.6	-0.1	-1.0	0.8	-0.7	-1.9	-1.3	1.4	0.4	2.0	0.3
Depression (Nagel 2018)	1.3	2.0	5.3	-1.0	-1.0	-0.9	-1.1	-2.1	-1.2	-1.4	1.1	-2.3	-1.5	-1.1	-1.9	-0.2	-1.5
Intelligence (Savage-Jansen 2018)	2.1	6.4	12.5	-3.5	2.3	-2.8	-1.5	-2.8	0.5	-2.8	3.4	0.3	1.4	-2.4	-3.0	-2.9	-3.1
Neuroticism (Nagel 2018)	0.1	0.3	1.7	0.2	-0.5	0.2	-0.6	-0.6	-0.6	0.1	0.2	-1.3	-0.7	0.5	-0.3	0.9	-0.3
Schizophrenia (2018)	2.0	4.2	9.5	-2.0	-0.6	-2.4	-1.8	-3.1	0.0	-2.2	2.2	-2.2	0.0	-2.1	-2.8	-2.5	-1.8
Schizophrenia vs Biploar Disorder	0.6	0.8	3.2	0.6	0.6	1.0	0.1	0.4	0.0	1.5	0.2	-0.1	0.0	1.8	1.0	1.4	0.9
Worry (Nagel 2018)	0.2	0.4	1.0	0.7	0.2	0.6	1.0	0.7	0.7	0.4	-0.3	0.9	0.4	0.1	0.6	0.2	0.6
Alzheimer’s Disease (in mother)	0.3	0.3	1.4	-0.3	1.2	0.2	-0.1	-0.1	0.8	0.4	0.8	0.4	1.1	0.7	0.1	0.3	-0.1
Alzheimer’s Disease (in father)	0.4	0.4	1.3	0.2	1.1	0.2	-0.5	-0.3	0.7	0.3	0.9	-0.1	1.0	0.9	-0.1	1.0	-0.2
Alzheimer’s Disease (including proxy)	1.1	1.6	6.2	-0.4	2.5	0.6	0.1	-0.0	1.8	1.0	1.6	0.9	2.3	1.5	0.4	1.0	-0.0
Crohns Disease (2017)	0.9	1.9	4.1	0.5	1.3	1.5	1.4	1.6	2.0	1.2	-0.3	1.8	1.6	1.1	1.6	1.1	1.0
Irritable Bowel Disease (IBD)	0.7	1.6	3.6	1.1	-0.5	1.5	1.3	1.9	0.8	1.2	-1.6	1.0	0.1	0.7	1.8	1.0	1.6
Ulcerative Colitis (UC)	0.4	0.8	2.9	0.8	-1.2	0.8	0.8	1.3	-0.3	0.7	-1.7	0.4	-0.8	0.0	1.1	0.1	1.1
Major Depression (MDD)	0.9	1.1	2.7	1.6	0.3	1.4	1.1	-0.1	0.0	1.5	0.9	-0.5	0.0	1.4	0.8	1.0	1.6
Reaction Time	0.3	0.6	1.6	0.4	0.9	0.3	0.7	0.8	0.5	1.1	0.1	1.3	1.0	0.7	1.0	-0.3	0.4
Verbal and Numeric Reasoning (VNR)	2.0	4.7	9.6	-3.1	1.9	-2.3	-0.9	-2.1	1.0	-2.8	2.4	0.7	1.3	-2.5	-2.6	-2.5	-2.6
Breast Cancer	0.4	0.9	2.4	-1.5	1.2	-1.0	-0.5	-0.9	0.2	-0.6	1.6	0.3	0.8	-0.6	-0.8	-1.2	-1.0
Ovarian Cancer	0.3	0.5	0.9	-0.5	-0.7	-0.5	-0.2	-0.8	-0.6	-0.9	0.2	-0.8	-0.9	-0.9	-0.9	-0.7	-0.3
Prostate Cancer	0.8	1.2	3.2	-1.8	0.7	-1.5	-0.9	-0.3	0.2	-1.3	0.4	0.7	0.7	-1.0	-0.9	-1.2	-1.8
Age at First Birth	0.4	0.6	2.2	-0.4	-0.7	-1.0	-1.3	-0.6	-1.5	-0.0	0.3	-1.0	-0.8	-0.0	-0.4	-0.7	-0.6
Bipolar Disorder (2011)	0.5	0.5	1.4	-0.4	0.1	-0.7	-0.9	-1.2	0.0	0.0	1.1	-1.1	0.0	-0.1	-0.9	0.0	-0.5
Body Mass Index (BMI) (2010)	1.6	2.2	5.6	1.8	-1.1	1.7	1.2	2.1	0.4	1.2	-2.4	0.6	-0.4	1.1	1.9	1.7	1.6
Coronary Artery Disease (CAD)	1.0	1.2	2.3	1.5	0.7	1.4	1.1	1.0	0.0	1.5	0.1	0.5	0.0	1.5	1.4	1.4	1.3
Crohns Disease (2012)	0.3	0.5	1.5	-1.2	0.8	-0.7	-0.6	-0.7	0.0	-0.8	1.1	0.1	0.0	-0.4	-0.7	-0.6	-0.9
Mean Putamen Volume	0.3	0.3	1.8	0.1	-0.6	0.6	1.4	0.4	0.0	-0.3	-0.6	0.4	0.0	-0.8	0.1	-0.3	0.7
Fasting Glucose	0.6	0.7	1.8	1.3	-1.3	0.8	1.0	0.3	-0.2	0.3	-1.0	-0.4	-1.2	-0.4	0.4	0.1	1.4
HbA1C	1.3	1.5	4.9	-0.9	-0.9	-0.9	-1.9	-1.6	-1.4	-0.9	0.6	-2.2	-1.3	-0.2	-1.4	0.2	-0.8
HDL Cholesterol	0.6	1.0	5.7	0.4	1.8	0.6	1.2	1.4	0.0	0.2	-0.2	2.4	0.0	0.2	0.9	0.4	0.0
LDL Cholesterol	0.1	0.2	0.8	-0.6	0.7	-0.3	-0.3	-0.5	0.0	-0.1	0.9	0.0	0.0	0.1	-0.3	-0.2	-0.4
Lupus	0.7	1.0	4.9	-0.1	-2.2	-0.7	-0.4	-0.2	0.0	-1.2	-1.7	-0.9	0.0	-1.5	-0.7	-1.0	-0.3
Neuroticism (2016)	1.3	1.9	3.2	-1.4	-1.7	-1.4	-1.3	-1.5	0.0	-1.8	0.3	-1.8	0.0	-1.6	-1.7	-1.5	-1.1
Primary Biliary Cirrhosis	0.5	0.7	2.1	-0.7	0.0	-0.8	-0.6	-1.5	0.0	-0.6	0.8	-1.4	0.0	-0.8	-1.1	-1.0	-0.3
Rheumatoid Arthritis	1.1	1.6	8.0	-0.1	1.9	1.1	2.3	1.4	0.0	0.3	0.1	2.8	0.0	-0.1	1.1	0.2	0.6
Schizophrenia (2014)	1.1	2.4	6.8	-1.8	-0.3	-1.5	-1.4	-2.6	0.0	-1.1	2.3	-2.1	0.0	-0.9	-2.0	-1.5	-1.1
Triglycerides	0.0	0.1	0.5	0.2	-0.6	0.0	0.0	0.2	0.0	-0.1	-0.7	-0.1	0.0	-0.2	0.0	-0.0	0.1
Type 2 Diabetes (T2D) (2012)	1.1	1.3	5.2	0.1	2.3	1.0	1.9	1.0	0.0	0.5	0.7	2.3	0.0	0.4	0.9	0.4	0.5
Ulcerative Colitis	0.1	0.2	0.8	-0.5	-0.9	-0.1	0.4	-0.1	0.0	-0.6	-0.5	-0.1	0.0	-0.9	-0.3	-0.6	0.1
Blood Eosinophil Count	1.3	10.4	20.6	3.8	-0.7	4.1	4.5	4.0	1.6	3.6	-3.0	2.4	0.3	2.2	4.2	2.4	4.4
Blood Platelet Count	0.5	5.2	17.1	0.4	-3.4	-0.8	-0.3	-2.4	-3.9	-0.7	0.2	-3.5	-4.1	-1.8	-1.6	-2.0	0.8
Blood Red Count	0.4	3.8	7.6	2.4	-0.3	2.4	1.5	2.1	0.5	2.8	-1.5	0.5	0.2	2.5	2.5	2.4	2.4
Blood White Count	0.3	2.3	7.3	0.3	-2.2	-0.4	-0.8	-1.6	-2.6	-0.3	0.2	-2.6	-2.7	-0.7	-1.0	-0.8	0.5
Heel T-Score	0.0	0.1	0.6	0.8	-0.2	0.2	-0.1	-0.0	-0.1	-0.1	-0.0	-0.4	-0.2	0.1	0.0	0.5	0.1
BMI	0.4	2.4	7.4	1.7	-0.8	1.6	-0.2	1.6	-0.1	1.8	-1.8	-0.5	-0.3	2.3	1.8	2.7	1.3
Height	0.0	0.6	1.8	-1.3	0.7	-0.6	-0.7	0.2	0.9	-1.0	-0.2	0.7	0.8	-0.5	-0.4	0.0	-1.1
Waist Hip Ratio (WHR)	2.1	9.4	27.2	3.6	-0.1	2.3	3.5	5.2	2.8	1.4	-4.6	4.8	1.7	0.4	3.7	1.1	1.6
Systolic Blood Pressure	1.7	8.6	19.6	4.1	0.3	2.6	1.9	4.4	1.6	3.4	-3.2	2.9	1.6	3.1	4.2	2.5	2.2
Smoking Status	0.3	0.7	2.4	-0.5	1.6	-0.4	-0.0	-0.3	1.2	-0.5	1.1	0.9	1.4	-0.4	-0.5	-0.5	-0.8
Allergy or Eczema	3.8	9.9	19.8	3.4	0.7	3.5	3.0	4.5	3.2	2.9	-3.2	3.2	2.0	2.6	4.0	3.5	2.6
Cardiovascular Disease	0.3	1.1	4.9	0.9	-1.1	1.0	0.3	1.7	0.3	0.6	-2.2	0.4	-0.4	0.6	1.2	1.4	0.8
Hypothyroidism (self reported)	0.4	0.9	2.1	-0.5	-1.5	-1.1	-1.3	-0.2	-1.5	-0.6	-1.0	-0.8	-1.3	-0.8	-0.5	-0.9	-0.8
Respiratory disease	1.7	3.8	8.2	2.8	-1.9	2.3	2.9	2.3	0.3	1.2	-2.7	1.0	-1.1	0.2	2.0	1.0	2.5
Type 2 Diabetes (T2D) (2018)	1.8	3.3	7.3	2.7	-0.8	2.1	0.9	2.0	0.2	2.2	-2.0	0.1	-0.2	2.2	2.2	2.5	2.1
Lung FEV1/FVC ratio	2.3	11.7	23.2	4.8	-2.2	3.7	2.2	4.3	-0.0	4.0	-4.6	0.9	-0.8	3.5	4.4	3.7	3.8
Lung FVC	3.7	18.9	43.7	-6.6	2.7	-4.5	-5.1	-6.3	-1.6	-3.3	6.6	-3.4	0.6	-1.6	-5.3	-2.8	-4.5
Neuroticism	0.2	0.6	1.4	-1.2	0.1	-0.4	-0.9	-1.2	-0.0	-0.8	0.7	-1.1	-0.2	-0.2	-1.1	0.4	-0.6
Chronotype (morning person)	0.8	1.8	4.7	2.1	-0.2	1.8	2.2	1.4	1.1	0.8	-1.2	0.9	0.2	0.5	1.3	1.3	1.6
Hair Pigment	0.0	0.9	2.1	-1.2	-0.8	-0.7	-0.0	-1.2	-1.0	-0.5	0.3	-0.7	-1.1	-1.1	-1.1	-1.4	-0.2
Tanning	0.1	1.4	4.3	0.6	0.8	0.6	0.5	1.9	1.7	0.6	-1.4	2.1	1.5	0.7	1.3	0.9	-0.1
Hand grip strength (left)	0.3	0.9	2.6	-0.8	-1.2	-0.6	-1.3	-0.8	-1.2	-0.8	-0.4	-1.6	-1.3	-0.4	-0.9	0.2	-0.6
Number of treatments/medications taken	4.2	7.5	15.8	3.6	-1.2	3.6	1.5	1.8	-0.3	3.8	-1.4	-1.2	-0.9	3.9	3.0	4.0	3.8
Average weekly spirits intake	0.8	1.0	2.2	0.9	-0.1	1.3	1.0	1.1	0.4	1.5	-0.6	0.5	0.2	1.2	1.4	1.0	1.3
Sensitivity / hurt feelings	0.2	0.4	1.6	0.2	0.9	0.7	0.0	0.0	0.9	0.2	0.5	0.0	0.8	0.8	0.1	1.2	0.2
Frequency of depressed mood in last 2 weeks	1.5	2.1	5.1	-0.8	-1.4	-1.3	-2.0	-1.7	-1.8	-1.3	0.2	-2.3	-1.7	-0.9	-1.6	-0.5	-1.0
Hearing difficulty/problems: Yes	1.7	2.6	6.9	1.7	-1.2	2.0	2.3	2.2	1.0	0.7	-2.6	1.1	-0.4	0.1	1.7	1.3	1.9
Relative age of first facial hair	0.8	1.7	5.4	-0.9	0.5	-0.8	-0.3	-2.3	-0.1	-1.5	2.2	-1.2	-0.3	-1.4	-2.0	-1.0	-0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.2	0.2	-1.5	-0.7	-0.2	-0.3	-1.3	-0.8	-0.8	-0.6	-1.4	-1.2	-0.6	-1.2	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.3	-0.5	0.9	0.2	0.0	0.0	1.1	-0.3	0.4	0.5	0.9	0.1	-0.1	0.6	-0.3
Ever had hysterectomy (womb removed)	0.8	0.9	2.6	-1.3	-0.1	-1.1	-0.9	-0.7	-0.1	-1.6	0.1	-0.2	-0.2	-1.3	-1.2	-0.8	-1.3
Systolic blood pressure, automated reading	2.2	6.5	13.2	3.5	1.0	2.4	1.1	3.3	1.3	3.5	-1.7	1.9	1.8	3.6	3.5	2.6	1.9
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	6.0	1.9	-2.4	1.4	0.6	0.8	-1.4	1.3	-1.8	-1.5	-2.1	0.9	1.1	1.4	2.0
Angina	0.3	0.4	0.9	1.0	-0.9	0.5	0.4	0.5	-0.8	0.8	-0.5	-0.3	-0.8	0.4	0.7	0.0	0.9
Medication for hormone replacement therapy	0.9	1.0	3.3	1.1	-0.5	0.8	-0.7	-0.3	-0.5	1.0	0.1	-1.6	-0.6	1.5	0.3	1.8	0.8
Vitamin and mineral supplements	0.5	0.6	1.4	-0.9	-0.4	-1.2	-0.9	-0.3	-0.7	-0.9	-0.1	0.0	-0.3	-0.9	-0.7	-1.2	-1.1
Supplements: Zinc	1.1	1.2	4.2	0.5	0.6	1.4	1.3	-1.1	0.1	1.3	2.1	-1.1	-0.1	1.0	0.1	0.8	1.7
Medication: Co-codamol	0.8	0.9	2.6	1.6	-1.1	1.1	0.9	1.0	-0.2	0.8	-1.4	-0.0	-0.7	0.4	1.0	0.7	1.3
Medication: Metformin	1.0	1.4	3.0	1.4	-0.3	1.7	1.0	1.0	0.3	1.6	-0.8	-0.2	-0.1	1.5	1.4	1.7	1.7
Diabetes (father)	0.4	0.4	1.6	0.4	-0.2	0.6	-0.2	0.6	-0.2	1.0	-0.4	-0.3	-0.1	1.2	0.8	1.1	0.6
Diabetes (mother)	1.5	2.0	4.4	2.1	-0.6	1.9	0.9	0.9	0.1	1.7	-0.9	-0.6	-0.4	1.7	1.4	2.1	2.0
Severe depression (siblings)	0.5	0.6	1.9	0.5	0.3	0.4	0.7	1.1	1.4	-0.4	-1.1	1.4	0.7	-0.5	0.4	0.3	-0.1
Pack years adult smoking proportion	0.2	0.4	1.5	0.5	-0.9	-0.4	-0.3	-0.1	-1.2	0.2	-0.3	-0.5	-1.0	-0.3	0.0	-0.9	0.2
Impedance of leg (right)	0.2	1.1	4.2	-0.5	0.8	-0.5	1.3	-0.5	0.7	-0.9	1.1	1.3	0.5	-1.7	-0.7	-2.0	-0.3
Leg fat-free mass (left)	0.2	1.0	4.3	0.2	-1.1	0.3	-1.4	0.7	-0.4	0.2	-1.7	-1.1	-0.7	1.1	0.4	2.1	-0.0
Trunk fat percentage	0.4	1.6	5.6	1.5	-0.2	1.5	0.1	1.1	0.4	1.5	-0.9	-0.4	0.1	2.0	1.4	2.4	1.3
Hand grip strength (right)	0.1	0.3	1.5	-1.2	0.2	-0.6	-0.8	-0.1	0.0	-0.5	0.0	0.0	0.2	-0.2	-0.4	-0.1	-0.8
Townsend deprivation index at recruitment	2.0	2.8	5.3	-1.3	-2.2	-1.6	-1.3	-1.2	-2.0	-1.9	-0.7	-1.6	-2.3	-2.2	-1.7	-1.5	-1.1
Current tobacco smoking	0.6	0.9	2.1	-0.9	-0.4	-0.9	-1.0	-1.4	-0.9	-0.9	0.7	-1.4	-0.8	-0.8	-1.3	-0.7	-0.7
Average weekly fortified wine intake	1.0	1.2	2.9	1.7	-1.3	0.9	0.3	0.9	-0.8	1.2	-1.4	-0.6	-1.0	0.9	1.1	0.9	1.3
Maternal smoking around birth	0.3	0.5	1.8	0.1	-0.5	0.2	0.9	0.9	0.5	-0.8	-1.3	1.0	-0.1	-1.1	0.2	-0.5	0.0
Fed-up feelings	0.7	1.3	4.6	-0.6	-1.6	-0.5	-1.4	-1.1	-1.6	-0.6	-0.3	-2.1	-1.8	-0.3	-0.9	0.3	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.9	-1.2	-0.9	-0.9	-0.5	-1.4	-0.8	-1.6	0.4	-1.1	-1.2	-1.7	-1.6	-1.0	-0.8
Relative age voice broke	0.3	0.4	1.4	-0.6	0.4	-0.1	0.5	-0.8	0.7	-1.1	0.8	0.0	0.1	-1.2	-0.9	-0.5	-0.2
Taking other prescription medications	1.7	2.6	5.3	2.0	-1.3	2.0	0.8	1.6	-0.2	1.9	-1.9	-0.4	-0.8	1.8	1.9	2.3	2.0
Age when periods started (menarche)	0.2	0.4	1.3	-0.3	-0.6	0.6	0.8	-0.8	-0.5	0.2	0.5	-1.2	-1.0	0.0	-0.3	0.4	0.9
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.7	0.3	-0.2	0.2	0.0	-0.0	0.8	-0.8	-0.5	-0.1	-0.0	-0.6	-0.4	0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.0	-0.4	0.6	-0.4	-1.0	-0.8	-0.1	-0.1	0.9	-0.7	0.3	0.5	-0.5	0.5	-0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.1	0.7	-0.3	1.0	1.1	0.1	0.3	0.4	-0.0	-0.2	-0.3	0.3	0.3	0.8	1.0
Qualifications: CSEs or equivalent	0.5	0.6	1.4	0.5	-1.2	0.7	1.0	0.8	-0.4	0.6	-1.2	-0.0	-0.9	-0.0	0.8	0.2	1.1
Serious illness, injury or assault to yourself	0.3	0.4	1.0	0.0	-0.8	-0.2	0.4	-0.6	-0.8	-0.4	0.1	-0.6	-1.0	-0.8	-0.5	-0.8	0.2
High blood pressure	0.4	1.1	3.1	1.5	-1.5	0.8	-0.0	1.1	-0.6	0.7	-1.8	-0.5	-1.0	0.7	1.0	1.2	0.9
Hayfever, allergic rhinitis or eczema	2.9	6.4	13.8	2.6	0.7	2.6	2.7	3.7	3.0	1.9	-2.7	3.2	1.9	1.5	3.1	2.2	1.9
Multivitamins +/- minerals	1.2	1.5	3.5	1.3	0.3	1.5	0.8	1.1	0.7	1.7	-0.6	0.2	0.5	1.8	1.5	1.9	1.4
Stomach or abdominal pain in last month	0.2	0.3	1.4	-0.0	-0.3	-0.1	0.8	-0.1	0.1	-0.6	-0.1	0.4	-0.4	-1.2	-0.3	-1.0	0.1
Supplements: Glucosamine	0.9	1.2	4.9	0.7	0.2	1.5	0.4	0.4	0.5	1.5	0.0	-0.6	0.2	1.9	0.9	2.2	1.3
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	5.2	-2.3	1.7	-1.4	-1.4	-1.0	0.8	-1.4	1.5	0.5	1.4	-0.6	-1.3	-0.7	-2.0
Medication: Atenolol	0.1	0.1	0.5	0.4	-0.4	0.4	-0.1	0.4	0.1	0.0	-0.6	-0.2	-0.2	0.2	0.3	0.7	0.2
Medication: Levothyroxine sodium	0.2	0.3	0.7	-0.7	-0.3	-0.7	-0.7	0.6	-0.1	-0.3	-0.9	0.6	0.1	-0.3	0.2	-0.3	-0.7
Sitting height	0.1	0.7	3.2	-1.1	1.0	0.0	-0.1	-0.0	1.8	-1.2	0.3	0.7	1.1	-0.6	-0.6	0.7	-0.8
Chronic bronchitis/emphysema (father)	1.4	1.7	2.8	-1.6	-0.8	-1.5	-1.3	-1.3	-1.0	-1.7	0.4	-1.1	-1.0	-1.5	-1.6	-1.1	-1.4
High blood pressure (mother)	0.5	0.7	2.1	1.2	-1.0	-0.1	-0.8	0.4	-1.4	1.1	-0.8	-0.7	-0.8	0.9	0.8	0.0	0.5
Body mass index (BMI)	0.6	2.6	8.8	1.8	-0.7	1.7	-0.2	1.4	0.0	2.0	-1.5	-0.7	-0.2	2.5	1.8	3.0	1.5
Impedance of leg (left)	0.3	1.2	3.6	-0.3	0.9	-0.2	1.8	-0.1	1.1	-1.0	0.9	1.7	0.7	-1.8	-0.5	-1.9	-0.2
Leg predicted mass (left)	0.2	1.0	4.6	0.2	-1.1	0.4	-1.4	0.7	-0.3	0.3	-1.6	-1.1	-0.6	1.1	0.4	2.1	-0.0
Trunk fat mass	0.4	1.8	7.1	1.5	-0.6	1.5	-0.2	1.3	0.3	1.3	-1.5	-0.5	-0.1	1.9	1.4	2.7	1.1
Waist circumference	0.9	3.5	8.0	2.5	-1.3	1.9	0.6	2.5	0.2	1.7	-2.8	0.2	-0.4	1.9	2.3	2.7	1.7
Number of incorrect matches in round	1.1	1.7	6.6	0.1	2.6	0.6	1.0	-0.3	1.8	0.8	2.4	1.1	2.2	0.9	0.3	0.3	0.3
Past tobacco smoking	0.3	0.6	3.4	0.7	-1.3	-0.1	-0.0	1.0	-0.6	-0.0	-1.9	0.2	-0.8	-0.4	0.5	-0.3	0.1
Alcohol usually taken with meals	1.0	1.7	3.8	1.2	-0.1	1.9	1.8	1.1	0.7	1.7	-0.6	0.4	0.1	1.3	1.6	1.4	1.9
Nervous feelings	0.5	0.9	2.7	0.8	0.9	0.8	0.9	1.3	1.6	0.2	-0.7	1.5	1.3	0.4	0.9	0.8	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.1	0.7	-1.4	0.7	0.6	0.1	-0.4	-0.3	-0.8	-0.7	-1.3	-0.5	-0.0	0.5	0.7
Hearing difficulty/problems with background noise	0.5	0.8	2.0	1.2	-1.4	0.8	0.5	0.4	-1.0	0.7	-1.0	-0.8	-1.3	0.4	0.6	0.5	1.2
Hair/balding pattern: Pattern 2	0.8	1.0	2.1	1.1	-0.2	1.3	0.7	1.2	0.4	1.3	-1.0	0.3	0.2	1.3	1.3	1.5	1.1
Had menopause	0.5	0.7	2.7	-0.8	1.1	0.2	-0.5	-1.1	0.6	-0.0	1.6	-0.8	0.7	0.7	-0.6	0.9	-0.1
Had other major operations	0.4	0.5	1.7	0.4	0.5	1.0	1.3	0.3	1.0	0.6	0.1	0.5	0.5	0.3	0.5	0.6	1.0
Forced vital capacity (FVC)	2.2	8.3	19.8	-4.5	2.3	-3.1	-3.5	-3.6	0.2	-3.0	3.8	-1.4	1.3	-1.3	-3.6	-1.3	-3.8
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.1	0.7	-0.9	0.3	-0.3	-0.6	-0.8	0.2	-0.0	-1.4	-1.0	0.3	-0.3	0.8	0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.4	0.5	-1.1	-0.0	0.3	-0.5	-0.8	-0.3	-0.0	-0.8	-1.2	-0.7	-0.4	-0.5	0.4
Qualifications: None of the above	0.6	1.2	3.8	0.9	-0.1	1.0	1.9	1.6	0.9	0.6	-1.2	1.7	0.4	-0.1	1.3	-0.1	1.1
Financial difficulties in last 2 years	0.9	1.2	2.3	-1.5	-0.6	-1.1	-1.0	-1.5	-1.1	-0.9	0.9	-1.3	-1.0	-1.0	-1.4	-1.0	-0.7
Mouth/teeth dental problems	0.4	0.6	1.7	0.9	-0.3	0.7	-0.1	0.3	-0.5	1.2	-0.4	-0.6	-0.3	1.3	0.7	0.9	0.9
Heart attack	0.5	0.6	1.7	0.9	0.2	0.9	0.5	0.6	0.0	1.3	0.2	0.1	0.3	1.3	1.0	0.8	1.0
Allergy	3.2	7.3	17.6	-3.1	0.0	-2.8	-2.9	-4.2	-2.5	-2.2	3.4	-3.2	-1.3	-1.5	-3.5	-2.1	-2.3
Pain all over the body in last month	0.2	0.3	1.1	-0.1	0.4	-0.2	-0.1	-0.9	0.3	-0.6	1.1	-0.3	0.1	-0.6	-0.8	-0.4	-0.2
Diabetes (self-reported)	1.3	2.0	4.2	2.0	-1.6	1.9	1.5	1.2	-0.1	1.0	-1.8	-0.4	-1.1	0.7	1.3	1.6	2.0
Hayfever/allergic rhinitis (self-reported)	2.0	2.6	5.6	1.9	1.2	1.5	2.0	2.0	2.0	1.3	-0.8	2.4	1.7	1.0	1.8	0.9	1.1
Medication: Ramipril	0.3	0.3	0.7	0.5	-0.3	0.7	0.8	0.8	0.3	0.6	-0.7	0.5	-0.0	0.2	0.8	0.4	0.7
Medication: Simvastatin	0.5	0.7	1.8	1.1	-0.6	1.1	1.2	0.8	0.3	0.8	-0.8	0.2	-0.4	0.3	0.9	0.7	1.4
Fluid intelligence score	1.3	2.6	5.7	-2.1	0.7	-1.9	-1.1	-1.7	0.2	-2.4	1.2	-0.1	0.2	-2.2	-2.2	-1.9	-2.0
Illnesses of siblings	0.7	1.0	2.5	-1.6	0.9	-1.0	-0.8	-1.4	0.2	-1.0	1.5	-0.4	0.5	-0.5	-1.4	-0.5	-1.2
Neuroticism score	0.3	0.6	1.6	-0.8	-0.7	-0.6	-0.8	-0.6	-0.3	-1.3	-0.2	-0.7	-0.7	-0.9	-1.0	-0.1	-0.8
Weight	0.4	1.9	8.7	1.2	-0.8	1.4	-0.6	1.2	0.2	1.2	-1.6	-0.8	-0.3	2.0	1.3	2.9	1.0
Impedance of arm (right)	0.3	1.4	5.0	-0.7	0.4	-1.4	-0.3	-1.6	-0.7	-1.1	1.7	-0.2	-0.1	-1.4	-1.4	-2.2	-1.0
Arm fat percentage (right)	0.5	2.0	6.5	1.9	-0.4	1.6	-0.1	0.9	-0.1	1.9	-0.8	-0.8	-0.2	2.4	1.5	2.5	1.5
Trunk fat-free mass	0.2	1.1	4.8	0.4	-1.2	0.6	-0.9	1.1	-0.0	0.2	-2.1	-0.7	-0.6	0.9	0.6	2.2	0.1
Hip circumference	0.3	1.4	4.7	0.6	-1.4	0.8	-1.0	0.1	-1.0	0.8	-1.0	-1.9	-1.3	1.4	0.4	2.2	0.8
Time employed in main current job	4.4	5.1	12.7	3.6	-1.3	2.9	2.0	1.9	-0.1	2.8	-1.8	-0.3	-0.8	2.3	2.6	2.5	3.3
Alcohol intake versus 10 years previously	2.4	3.6	10.1	2.5	-1.1	1.8	2.6	2.8	1.1	0.9	-3.2	2.0	-0.1	-0.0	2.1	1.0	1.7
Father’s age at death	1.7	2.3	4.5	-2.0	-0.6	-2.1	-2.0	-0.9	-1.0	-2.0	-0.2	-0.5	-0.7	-1.7	-1.6	-1.6	-2.1
Worrier / anxious feelings	0.8	1.4	5.3	1.6	-2.3	0.8	0.8	0.7	-0.8	-0.1	-2.0	-0.6	-1.9	-0.6	0.4	0.4	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	4.0	-0.9	-0.5	-1.3	-0.6	-1.1	-0.4	-1.9	0.5	-0.3	-0.7	-2.0	-1.5	-1.6	-1.2
Falls in the last year	0.8	1.1	3.7	0.7	0.2	1.7	1.4	-0.3	0.3	1.3	0.9	-0.8	-0.2	1.1	0.6	1.2	1.9
Hair/balding pattern: Pattern 3	0.2	0.3	1.4	0.5	-0.7	0.1	-0.6	-0.4	-0.7	0.3	-0.1	-1.2	-0.8	0.5	-0.1	0.7	0.3
Number of live births	0.6	0.9	1.7	-0.7	-0.6	-0.9	-1.0	-1.3	-0.9	-1.0	0.6	-1.2	-0.9	-0.9	-1.3	-0.7	-0.7
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	6.9	-2.6	1.6	-1.7	-2.3	-2.0	0.0	-1.3	2.3	-0.9	1.0	-0.2	-1.9	-0.4	-2.1
Pulse rate	2.0	3.4	8.9	3.0	-2.6	2.0	1.5	1.0	-1.1	1.3	-2.1	-1.3	-2.2	0.7	1.3	1.5	2.6
Happiness	0.6	0.7	1.9	-1.4	-0.4	-0.7	-1.0	-1.1	-0.5	-1.0	0.4	-1.2	-0.6	-0.7	-1.2	-0.1	-0.7
Noisy workplace	1.7	2.1	5.7	1.9	-0.7	1.9	1.4	0.9	-0.3	2.1	-0.8	-0.5	-0.6	1.7	1.6	1.5	2.4
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.2	-1.3	-0.6	-1.0	-0.6	-1.5	-1.0	-1.0	0.6	-1.2	-1.0	-1.1	-1.4	-1.1	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.0	0.4	-1.0	0.4	1.4	0.1	-0.1	-0.5	-0.7	0.1	-0.9	-1.2	-0.1	-0.7	0.8
Mouth/teeth dental problems: Dentures	0.1	0.2	1.0	0.2	-0.2	0.7	1.0	0.4	0.5	0.1	-0.3	0.3	-0.0	-0.1	0.4	0.4	0.7
Asthma	1.2	2.4	7.6	2.2	-1.6	1.5	1.6	2.3	0.2	0.9	-2.8	1.0	-0.7	0.4	1.8	1.0	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.7	0.3	-0.2	-0.2	-0.2	-0.8	-0.6	0.1	0.8	-0.7	-0.5	-0.0	-0.4	-0.2	0.1
Medication: Cholesterol lowering	0.5	0.8	1.8	0.8	0.2	0.9	1.2	1.3	0.5	1.2	-0.7	1.2	0.5	0.6	1.4	0.2	1.0
Depression (self-reported)	0.2	0.2	0.7	-0.5	0.7	-0.3	-0.3	-0.5	0.4	-0.4	0.9	0.1	0.6	-0.1	-0.5	-0.2	-0.5
Medication: Lansoprazole	0.5	0.6	2.0	-0.1	-1.2	0.2	0.9	-0.6	-0.8	-0.5	0.0	-0.8	-1.4	-1.0	-0.5	-0.7	0.7
Prospective memory result	0.3	0.4	1.1	-0.7	-0.6	-0.4	0.1	-0.7	-0.8	-0.4	0.2	-0.5	-0.8	-0.8	-0.6	-1.0	0.0
Lung cancer (father)	1.6	1.9	3.7	1.9	0.4	1.7	1.4	1.7	1.1	1.4	-1.0	1.2	0.8	1.4	1.7	1.4	1.4
Illnesses of mother	0.3	0.4	1.5	-0.7	0.1	-0.0	0.9	-0.2	0.7	-1.0	0.2	0.6	0.0	-1.2	-0.6	-0.6	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	10.3	-3.2	1.6	-2.2	-2.5	-2.3	0.0	-1.9	2.3	-0.8	0.9	-0.8	-2.3	-1.0	-2.7
Pulse wave Arterial Stiffness index	0.8	0.9	3.2	0.9	0.1	1.5	1.8	0.6	0.9	0.7	-0.2	0.4	0.1	0.4	0.9	0.9	1.5
Impedance of arm (left)	0.3	1.2	4.1	-0.7	0.8	-1.2	0.0	-1.4	-0.2	-0.9	1.7	0.1	0.2	-1.3	-1.2	-2.0	-0.9
Arm fat mass (right)	0.5	2.1	8.7	1.6	-0.5	1.6	-0.3	1.1	0.1	1.7	-1.2	-0.9	-0.1	2.4	1.4	2.9	1.3
Trunk predicted mass	0.2	1.1	5.0	0.4	-1.2	0.7	-0.9	1.1	-0.1	0.2	-2.1	-0.7	-0.6	0.9	0.6	2.2	0.2
Standing height	0.1	0.6	2.0	-1.1	-0.2	-0.5	-0.9	-0.1	0.6	-1.4	-0.6	-0.1	0.0	-0.8	-0.8	0.4	-1.1
Length of working week for main job	0.2	0.2	0.9	-0.2	-0.6	-0.1	0.4	0.5	-0.2	-0.1	-0.9	0.3	-0.4	-0.6	0.2	-0.4	0.1
Exposure to tobacco smoke at home	1.1	1.2	3.4	1.5	-1.4	0.9	1.2	1.4	-0.5	0.8	-1.8	0.5	-1.0	0.0	1.2	-0.0	1.3
Breastfed as a baby	1.7	2.0	4.5	-0.6	-1.5	-1.0	-0.6	-2.0	-2.1	-0.8	0.8	-2.0	-2.1	-1.3	-1.5	-1.6	-0.1
Tense / ‘highly strung’	0.2	0.4	0.9	0.5	-0.4	0.8	0.9	0.9	0.7	0.1	-0.9	0.6	-0.0	-0.1	0.6	0.5	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	4.6	-0.8	-1.5	-1.6	-2.1	-1.5	-2.0	-1.6	0.0	-2.0	-1.8	-1.2	-1.8	-1.0	-1.4
Hair/balding pattern: Pattern 4	0.4	1.0	2.4	1.5	-0.3	0.8	0.9	1.5	-0.0	1.4	-1.1	0.9	0.1	0.9	1.6	0.3	1.0
Birth weight of first child	1.2	2.1	6.0	-1.4	-1.0	-1.7	-1.3	0.2	-0.2	-2.4	-1.8	0.4	-0.6	-2.3	-1.2	-1.3	-1.9
Peak expiratory flow (PEF)	0.5	1.1	4.2	1.1	0.1	0.6	-0.5	1.2	-0.3	1.7	-0.9	0.0	0.4	2.1	1.5	1.4	0.6
Pulse wave reflection index	1.2	1.5	3.1	-1.7	1.7	-0.9	0.4	-0.7	0.9	-0.8	1.8	1.2	1.3	-1.1	-0.8	-1.7	-1.0
Ever highly irritable/argumentative for 2 days	0.5	0.7	1.6	-0.4	-0.6	0.1	1.3	-1.0	-0.4	-0.4	0.9	-0.5	-1.0	-1.2	-0.7	-1.1	0.7
Loud music exposure frequency	2.1	2.3	5.2	-2.1	0.3	-1.4	-0.1	-1.9	-0.2	-1.8	1.8	-0.2	-0.3	-2.2	-1.9	-2.3	-1.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	1.3	-0.1	0.7	0.4	0.5	-0.8	0.3	0.1	1.2	-0.2	0.3	0.1	-0.4	0.0	0.4
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	4.6	-2.2	0.5	-1.9	-2.0	-1.9	-0.4	-2.0	1.6	-0.9	0.1	-1.3	-2.1	-1.2	-2.2
Blood clot in the leg (DVT)	2.1	2.7	5.8	1.9	-1.2	1.9	1.9	2.2	0.2	1.6	-2.4	0.8	-0.5	0.9	2.1	1.2	2.0
Medication: Paracetamol	0.2	0.3	1.0	1.0	-0.2	0.8	0.6	-0.2	-0.0	0.4	0.4	-0.6	-0.4	0.4	0.2	0.7	0.9
Headache pain in last month	0.9	1.6	3.2	-0.8	-1.5	-1.0	-1.1	-1.3	-1.6	-1.4	-0.1	-1.6	-1.8	-1.4	-1.4	-1.0	-0.6
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.2	0.1	0.3	0.1	0.0	-0.4	0.1	0.1	0.4	-0.2	0.2	0.2	-0.1	0.1	0.2
Glaucoma (self-reported)	1.5	1.7	6.4	0.1	-2.5	-0.6	-0.7	-0.3	-2.3	-0.5	-1.3	-1.5	-2.4	-0.9	-0.4	-0.8	0.1
Gout (self-reported)	0.8	1.0	3.9	1.0	0.6	0.5	0.9	1.6	1.2	0.5	-1.0	2.0	1.1	0.2	1.2	-0.1	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.0	-0.8	-0.6	-1.1	-1.4	-0.3	-1.0	-0.4	-0.2	-0.5	-0.5	-0.3	-0.4	-0.8	-0.9
Medication: Amlodipine	2.0	2.8	10.2	0.6	-3.2	-0.6	0.2	-0.3	-2.6	-0.7	-1.6	-1.3	-3.1	-1.8	-0.4	-1.7	0.5
Medication: Ventolin 100micrograms inhaler	1.5	2.0	5.7	2.4	-0.3	1.7	2.1	1.6	0.9	1.3	-1.3	1.1	0.1	0.6	1.6	0.9	1.7
Birth weight	0.8	1.6	5.9	1.2	-2.3	0.2	-0.3	1.2	-1.7	0.6	-2.4	-0.6	-1.8	0.4	0.9	0.4	0.6
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.5	-0.2	0.9	0.8	1.2	0.5	1.0	0.8	0.5	0.9	0.9	0.4	0.7	0.2	0.8
High blood pressure (siblings)	0.4	0.6	2.2	0.1	-1.4	-0.4	-0.7	-0.0	-1.5	0.0	-0.8	-0.9	-1.4	-0.2	-0.0	-0.5	0.1
Forced vital capacity (FVC), Best measure	2.7	9.7	23.3	-4.8	2.4	-3.5	-3.8	-3.8	-0.1	-3.2	3.9	-1.3	1.3	-1.6	-3.8	-1.9	-4.1
Body fat percentage	0.4	1.6	5.2	1.6	-0.4	1.5	0.2	0.9	0.2	1.6	-0.8	-0.5	-0.1	1.9	1.3	2.3	1.4
Leg fat percentage (right)	0.2	0.8	2.5	1.1	-0.1	1.0	-0.1	0.5	0.0	1.3	-0.3	-0.5	-0.0	1.5	1.0	1.6	1.0
Arm fat-free mass (right)	0.3	1.5	7.5	0.5	-0.5	1.3	-0.3	1.6	0.8	0.7	-1.9	0.0	0.2	1.5	1.2	2.7	0.6
Exposure to tobacco smoke outside home	0.9	1.3	4.2	-0.6	-1.7	0.3	0.5	-1.3	-1.0	-1.0	0.3	-1.7	-2.0	-1.2	-1.1	-0.1	0.6
Comparative body size at age 10	1.0	2.8	9.8	1.2	-0.4	1.5	-0.9	1.6	-0.1	2.2	-1.6	-0.6	0.2	3.0	1.9	3.1	1.1
Number of full brothers	0.4	0.5	2.1	-0.6	1.1	-0.3	0.3	-0.7	0.6	-0.5	1.5	0.3	0.8	-0.3	-0.6	-0.4	-0.5
Worry too long after embarrassment	0.1	0.2	0.5	-0.2	-0.1	-0.1	0.3	-0.7	0.2	-0.6	0.5	-0.4	-0.3	-0.7	-0.7	-0.1	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.8	-1.7	1.3	-1.2	-0.7	-1.0	0.6	-1.1	1.6	0.5	1.0	-0.9	-1.1	-1.2	-1.4
Wheeze or whistling in the chest in last year	1.1	1.9	5.2	1.7	-2.3	1.2	0.8	0.5	-1.4	1.0	-1.6	-1.3	-2.1	0.5	0.8	0.8	1.8
Number of children fathered	1.2	1.3	3.6	1.5	0.0	0.9	1.9	1.6	0.6	1.1	-0.9	1.7	0.4	0.2	1.5	-0.3	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	-0.0	0.5	-0.1	-0.1	0.2	-0.1	0.5	0.4	0.4	0.5	0.4	0.3	-0.4	-0.1
Age at first live birth	0.3	0.5	3.1	-0.3	-1.2	-0.2	-0.5	0.6	-0.2	-0.8	-1.8	-0.1	-0.8	-0.6	-0.1	0.3	-0.4
Pulse wave peak to peak time	1.1	1.2	4.4	-1.2	0.2	-1.7	-2.1	-0.8	-0.8	-1.0	0.4	-0.5	0.0	-0.5	-1.1	-0.9	-1.8
Health satisfaction	0.5	0.7	2.1	1.1	-0.9	1.1	1.0	0.3	-0.2	0.7	-0.6	-0.6	-0.9	0.4	0.6	0.8	1.4
Shortness of breath walking on level ground	0.4	0.5	1.7	0.8	-1.2	0.4	0.6	-0.5	-0.6	-0.1	-0.0	-0.9	-1.3	-0.5	-0.3	0.0	0.7
Qualifications: College or University degree	0.8	2.6	6.1	-2.5	0.9	-2.0	-2.1	-1.9	-0.4	-1.5	1.8	-0.8	0.4	-0.9	-2.0	-1.1	-2.2
Eye problems/disorders: None of the above	0.9	1.0	2.2	0.8	1.0	1.0	1.1	1.2	1.4	0.9	-0.3	1.5	1.3	0.8	1.2	0.6	0.6
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.5	0.8	-0.4	0.5	-0.2	0.6	-0.5	1.2	-0.5	-0.3	-0.2	1.2	0.9	0.9	0.6
Emphysema/chronic bronchitis	0.8	0.9	2.3	-0.7	-0.9	-0.8	-1.0	-1.3	-1.3	-0.8	0.4	-1.5	-1.2	-0.7	-1.1	-0.6	-0.5
Medication for pain relief, constipation, heartburn	0.6	1.1	3.2	-1.4	1.0	-1.3	-1.0	0.3	0.7	-1.0	-0.2	1.4	1.3	-0.7	-0.4	-0.9	-1.8
Neck or shoulder pain in last month	1.2	1.7	3.7	1.2	1.2	1.3	1.9	1.3	1.8	1.0	-0.1	1.9	1.5	0.6	1.3	0.4	1.1
Medication: Blood pressure	0.5	0.8	3.3	0.6	-1.8	-0.3	-0.5	0.1	-1.5	-0.2	-1.1	-1.0	-1.6	-0.4	-0.1	-0.2	0.1
Angina (self-reported)	0.2	0.2	0.8	0.7	-0.7	0.2	0.0	0.0	-0.9	0.5	0.0	-0.5	-0.7	0.3	0.3	-0.3	0.5
Migraine (self-reported)	1.7	2.1	5.8	-2.4	1.7	-1.2	-1.1	-0.4	1.7	-1.8	0.7	1.1	1.7	-1.1	-1.2	-0.5	-2.1
Medication: Ibuprofen	0.3	0.3	1.2	1.1	-0.1	0.6	0.9	-0.3	-0.2	0.7	0.6	-0.3	-0.3	0.3	0.2	0.0	1.0
Medication: Allopurinol	0.3	0.4	2.0	0.6	0.2	-0.1	0.3	1.1	0.6	-0.2	-0.9	1.4	0.6	-0.4	0.5	-0.5	-0.4
Medication: Omeprazole	0.9	1.1	2.3	1.2	-1.4	1.4	1.4	1.0	-0.1	0.4	-1.5	-0.1	-1.1	0.0	0.8	0.9	1.5
Medication: Seretide 50 evohaler	0.5	0.5	1.4	-1.1	0.2	-1.0	-1.1	-0.4	-0.0	-0.9	0.3	0.0	0.2	-0.6	-0.7	-0.6	-1.2
Mean time to correctly identify matches	0.5	0.9	2.3	1.0	0.7	1.0	1.1	0.8	0.5	1.5	0.3	0.8	0.8	1.1	1.2	0.3	1.1
Heart disease (mother)	0.7	0.9	3.5	-0.8	1.3	0.1	0.7	0.7	1.9	-0.5	0.1	1.7	1.5	-0.4	0.1	0.1	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.0	3.5	11.1	2.2	1.0	2.4	3.3	1.7	2.0	1.7	-0.1	2.1	1.3	1.0	2.0	1.0	2.2
Whole body fat mass	0.5	1.9	7.8	1.5	-0.5	1.6	-0.2	1.0	0.2	1.6	-1.1	-0.8	-0.1	2.2	1.4	2.8	1.3
Leg fat mass (right)	0.3	1.3	5.6	1.1	-0.4	1.3	-0.2	0.9	0.2	1.3	-1.0	-0.6	-0.1	1.9	1.2	2.4	1.1
Arm predicted mass (right)	0.2	1.2	6.2	0.5	-0.7	1.1	-0.4	1.3	0.6	0.4	-1.9	-0.2	-0.1	1.1	0.9	2.5	0.5
Pulse rate, automated reading	1.3	4.2	12.5	2.7	-3.5	1.6	1.8	1.7	-1.3	0.6	-3.5	-0.6	-2.8	-0.5	1.3	0.8	2.2
Alcohol intake frequency.	0.3	0.6	2.5	0.6	-1.4	0.3	0.2	-0.5	-1.1	0.0	-0.3	-1.3	-1.6	-0.3	-0.2	-0.0	0.8
Comparative height size at age 10	0.0	0.3	1.7	-0.4	0.4	0.2	-0.6	-0.1	0.7	-0.1	0.0	-0.4	0.4	0.5	-0.2	1.3	-0.2
Number of full sisters	0.7	0.8	3.4	1.8	-0.1	0.7	0.7	1.2	0.3	1.0	-1.0	0.7	0.2	0.7	1.2	0.5	0.8
Suffer from ‘nerves’	0.0	0.0	0.2	-0.1	-0.4	-0.1	-0.1	0.0	-0.2	-0.2	-0.3	-0.1	-0.3	-0.2	-0.1	-0.1	-0.1
Overall health rating	1.6	3.5	8.6	2.9	-2.1	2.0	2.1	2.2	-0.0	1.2	-2.9	0.5	-1.3	0.4	1.9	1.2	2.3
Chest pain or discomfort	2.4	3.5	6.7	-2.3	0.9	-2.5	-1.4	-1.5	0.1	-2.5	1.3	0.4	0.5	-2.4	-2.2	-2.5	-2.6
Had major operations	3.9	4.6	7.7	-2.4	-0.5	-2.7	-2.8	-2.5	-1.7	-2.5	1.4	-1.8	-1.1	-1.9	-2.7	-2.0	-2.5
Age at last live birth	0.6	0.9	3.0	-0.3	-0.8	-1.0	-1.0	0.6	0.1	-1.6	-1.7	0.5	-0.3	-1.3	-0.5	-0.4	-1.3
Family relationship satisfaction	0.3	0.3	1.4	-0.5	-0.3	-0.2	-1.0	-0.7	-0.6	-0.1	0.3	-1.2	-0.5	0.3	-0.4	0.4	-0.1
Leg pain on walking	0.9	1.1	4.2	1.5	-1.0	1.6	1.8	-0.0	-0.2	0.8	-0.0	-0.7	-1.1	0.1	0.5	0.5	2.0
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.3	8.5	2.9	-1.8	2.1	1.6	1.9	-0.3	1.6	-2.5	-0.1	-1.2	1.2	1.9	1.8	2.3
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.5	0.3	-1.0	-0.2	-0.1	-0.6	-1.6	0.4	0.4	-1.0	-1.2	-0.1	-0.2	-0.9	0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.6	0.1	0.3	-0.3	-1.3	-0.0	-0.1	0.2	-0.0	-0.3	0.3	0.7	-0.0	0.6	-0.5
Medication: Aspirin	0.7	0.9	2.4	1.0	-0.3	0.7	-0.0	-0.7	-1.1	1.4	0.9	-1.6	-0.7	1.4	0.3	0.8	1.3
Supplements: Vitamin C	0.9	1.0	3.4	-0.4	-0.2	-0.5	-0.4	-1.9	-0.8	-0.9	1.5	-1.5	-0.9	-0.8	-1.4	-0.7	-0.2
Knee pain experienced in last month	1.0	1.6	4.4	2.1	-0.5	1.2	0.9	1.2	-0.4	1.9	-0.9	0.2	-0.2	1.5	1.7	0.9	1.5
Hypertension (Self-reported)	0.5	1.3	3.1	1.6	-1.7	1.0	0.0	1.0	-0.7	0.7	-1.8	-0.8	-1.2	0.8	0.9	1.4	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	5.8	1.0	-0.5	1.6	2.4	0.5	0.3	0.8	-0.2	0.3	-0.5	0.0	0.8	0.3	1.9
Illnesses of father: Heart disease	0.4	0.5	1.6	0.9	0.1	0.9	0.6	0.1	-0.1	1.3	0.3	-0.3	-0.0	1.1	0.7	0.8	1.1
Illnesses of siblings: Diabetes	2.1	2.6	5.6	2.4	-1.0	2.0	2.0	2.0	0.2	1.7	-1.8	0.8	-0.4	1.0	2.0	1.0	2.2
Smoking status: Previous	0.2	0.3	0.9	-0.2	0.8	0.3	-0.1	-0.4	0.5	0.2	0.9	-0.2	0.6	0.7	-0.1	0.8	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.9	-0.3	0.3	0.4	0.7	1.2	1.2	-0.2	-1.2	1.4	0.7	-0.2	0.6	0.3	-0.0
Whole body fat-free mass	0.2	1.3	5.9	0.4	-1.2	0.7	-1.0	1.1	-0.1	0.3	-2.1	-0.9	-0.6	1.1	0.7	2.4	0.2
Leg fat-free mass (right)	0.2	1.1	5.2	0.4	-1.2	0.5	-1.2	0.8	-0.3	0.3	-1.9	-1.0	-0.7	1.1	0.5	2.3	0.1
Arm fat percentage (left)	0.5	1.9	6.4	1.7	-0.3	1.5	-0.1	0.9	0.1	1.9	-0.7	-0.8	-0.0	2.3	1.4	2.5	1.4
Average weekly red wine intake	1.4	2.1	5.0	-2.1	0.3	-1.9	-1.7	-1.1	-0.1	-2.1	0.8	-0.2	0.1	-1.6	-1.7	-1.2	-2.2
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.2	-0.3	0.5	-0.5	-1.0	0.4	0.8	-0.7	-0.5	0.6	0.8	-0.1	-0.2	0.4	-1.1
Mood swings	0.4	0.8	2.4	0.1	-1.2	0.1	-1.4	-0.1	-0.8	-0.1	-0.9	-1.6	-1.0	0.6	-0.2	1.4	-0.1
Loneliness, isolation	0.5	0.7	2.4	0.1	-0.4	1.0	0.6	-1.0	-0.1	0.1	0.8	-1.6	-0.9	0.3	-0.4	1.1	1.1
Long-standing illness, disability or infirmity	0.4	0.6	1.7	0.9	-1.3	0.8	0.9	0.3	-0.5	0.2	-1.0	-0.4	-1.2	-0.2	0.4	0.3	1.1
Ever had bowel cancer screening	0.9	1.0	2.7	-1.1	0.3	-0.9	-0.7	-1.6	-0.1	-1.3	1.5	-0.9	-0.2	-1.0	-1.6	-0.7	-0.9
Diabetes diagnosed by doctor	1.6	2.7	5.7	2.2	-0.8	2.3	1.6	1.4	0.5	1.8	-1.3	-0.2	-0.4	1.6	1.7	2.2	2.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.5	-0.1	-0.3	-0.7	-0.7	-0.3	-0.3	-0.6	-0.3	-0.2	-0.3	-0.6	-0.5	-0.5	-0.6
Friendships satisfaction	0.2	0.2	1.0	-0.1	1.0	0.2	0.3	-0.2	0.6	0.5	0.8	0.3	0.8	0.5	0.1	0.1	0.2
Qualifications: nursing, teaching	5.4	8.3	15.2	-3.8	-0.8	-3.2	-3.4	-3.9	-2.6	-2.9	2.1	-3.3	-1.9	-2.2	-3.8	-2.1	-2.7
Commuting to job workplace: Walk	1.4	1.5	4.8	-0.8	-0.3	-0.8	0.2	-1.7	-0.0	-2.0	1.1	-0.7	-0.8	-2.2	-1.9	-1.3	-0.7
Eye problems/disorders: Cataract	0.5	0.5	1.4	0.7	-0.8	0.9	0.8	-0.2	-0.5	0.6	-0.1	-0.9	-0.9	0.5	0.3	0.8	1.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.5	0.3	-1.5	-0.4	0.2	0.4	-0.4	-1.2	-1.5	0.2	-1.1	-1.6	-0.3	-0.8	-0.3
Medication for cholesterol	1.3	1.9	7.2	-1.8	0.7	-1.1	1.1	-0.4	0.5	-1.5	0.7	1.6	0.5	-2.3	-0.9	-2.7	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.5	0.8	-1.6	0.2	-0.8	0.3	-1.1	0.3	-1.3	-1.2	-1.3	0.5	0.3	1.0	0.4
Back pain experienced in last month	0.9	1.3	4.0	-1.2	1.7	-0.1	0.6	0.6	2.0	-0.6	0.4	1.9	1.9	-0.4	0.1	-0.2	-0.8
Mineral and other dietary supplements	1.4	1.8	4.6	-0.9	-0.9	-1.8	-0.9	-0.8	-1.1	-1.9	-0.2	-0.2	-1.0	-2.1	-1.4	-2.1	-1.5
Breast cancer (self-reported)	2.1	2.5	5.8	1.2	1.7	1.3	1.0	1.5	1.3	2.4	0.2	1.7	1.9	2.2	2.0	0.9	1.2
Asthma (self-reported)	1.2	2.4	6.9	2.2	-1.6	1.5	1.8	2.2	0.1	1.0	-2.6	0.9	-0.8	0.3	1.8	0.9	1.7
Osteoporosis (self-reported)	1.1	1.4	4.7	-0.1	-2.0	-0.5	-0.6	-0.9	-1.8	-0.8	-0.6	-1.8	-2.2	-1.0	-0.9	-0.4	-0.0
Osteoarthritis (self-reported)	1.9	2.5	7.1	2.0	-0.1	1.8	0.7	1.9	1.0	1.6	-1.7	0.4	0.5	2.0	1.9	2.7	1.4
Medication: Aspirin	1.2	1.5	3.8	1.6	-0.5	1.3	0.4	-0.2	-1.0	1.9	0.4	-1.4	-0.8	1.8	0.9	1.2	1.8
Medication: Gliclazide	0.2	0.3	0.7	-0.4	-0.6	-0.2	-0.2	-0.6	-0.7	-0.3	0.2	-0.8	-0.8	-0.4	-0.5	-0.4	0.1
Illnesses of father: None of the above (group 1)	0.8	1.0	3.8	-0.2	0.9	0.4	0.9	1.3	1.9	-0.4	-0.9	1.9	1.3	-0.4	0.5	0.2	-0.2
Smoking status: Current	0.6	0.9	2.0	-0.8	-0.1	-1.0	-1.2	-1.4	-0.9	-0.8	1.0	-1.2	-0.6	-0.6	-1.2	-0.8	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	6.2	-2.5	1.4	-1.9	-2.5	-2.1	-0.5	-1.2	2.4	-1.1	0.7	-0.2	-1.9	-0.8	-2.2
Whole body water mass	0.2	1.3	6.5	0.5	-1.2	0.8	-1.0	1.1	-0.0	0.4	-2.1	-0.8	-0.6	1.3	0.8	2.5	0.3
Leg predicted mass (right)	0.2	1.1	5.0	0.3	-1.2	0.5	-1.2	0.8	-0.3	0.3	-1.8	-1.0	-0.7	1.1	0.5	2.2	0.1
Arm fat mass (left)	0.5	2.0	8.5	1.5	-0.3	1.5	-0.4	1.2	0.3	1.7	-1.1	-0.7	0.1	2.4	1.5	2.9	1.2
Number of self-reported non-cancer illnesses	1.4	2.3	5.2	2.3	-0.8	1.8	1.5	2.0	0.2	1.7	-1.8	0.7	-0.2	1.3	2.0	1.3	1.9
Average weekly champagne plus white wine intake	0.3	0.5	1.9	-1.0	-0.0	-0.6	-0.1	-0.9	-0.9	-0.2	1.0	-0.3	-0.4	-0.5	-0.5	-1.4	-0.2
Miserableness	0.6	1.1	4.6	0.7	-2.1	-0.1	-0.6	0.3	-1.2	-0.6	-1.8	-1.0	-1.8	-0.5	-0.1	0.3	0.0
Guilty feelings	1.7	2.5	4.3	-1.4	-1.6	-1.8	-1.7	-1.2	-1.6	-2.1	-0.5	-1.3	-1.7	-2.0	-1.8	-1.6	-1.5
Wears glasses or contact lenses	0.4	0.4	1.0	0.2	0.5	0.6	0.3	0.8	1.0	0.5	-0.6	0.7	0.7	0.6	0.7	0.8	0.4
Ever taken oral contraceptive pill	1.5	1.7	5.8	-0.7	1.9	0.3	0.7	1.3	2.4	-0.1	-0.3	2.4	2.3	0.1	0.7	0.4	-0.6
Hearing aid user	0.4	0.4	1.3	0.2	0.6	0.8	0.6	0.2	0.3	1.1	0.3	0.1	0.5	1.0	0.7	0.6	0.9
Mother’s age at death	3.4	4.2	9.5	-0.2	-2.9	-1.6	-2.4	-1.7	-3.0	-1.8	-1.0	-3.1	-3.1	-1.4	-1.9	-0.7	-1.1
Financial situation satisfaction	0.5	0.7	2.0	-1.4	0.1	-0.8	-0.1	-0.6	0.2	-1.2	0.3	0.2	-0.0	-1.4	-1.0	-0.9	-0.9
Tinnitus: Yes, now most or all of the time	1.4	1.6	5.4	-0.0	2.3	0.3	0.3	0.8	1.4	1.3	0.9	1.7	2.3	1.5	1.1	0.2	-0.0
Commuting to job workplace: Public transport	0.5	0.6	1.8	1.1	-0.7	1.0	0.5	0.6	0.1	0.3	-1.0	-0.4	-0.5	0.5	0.5	1.3	0.8
Eye problems/disorders: Glaucoma	3.1	3.6	12.1	-0.0	-3.3	-0.7	-1.4	-1.2	-3.2	-0.7	-1.1	-3.1	-3.5	-0.8	-1.1	-0.4	0.2
Medication: Blood pressure	0.7	1.4	4.9	1.6	-0.4	1.2	-0.2	1.4	0.4	1.1	-1.5	-0.1	0.1	1.6	1.3	2.2	0.8
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.8	-0.3	0.9	0.1	0.1	-0.0	0.8	0.0	0.6	0.4	0.8	0.3	0.0	0.2	-0.1
Supplements: Fish oil (including cod liver oil)	2.0	2.6	6.7	1.3	1.1	2.0	1.1	1.0	1.0	2.5	0.4	0.4	1.2	2.6	1.8	2.1	1.8
High cholesterol (Self-reported)	0.1	0.1	0.5	0.2	0.5	0.2	-0.3	0.2	0.3	0.5	0.2	0.1	0.5	0.7	0.3	0.5	0.0
Medication: Bendroflumethiazide	0.4	0.6	3.3	0.8	-0.1	0.8	-0.4	0.9	0.5	0.5	-0.8	-0.1	0.3	1.2	0.7	1.8	0.3
Medication: Paracetamol	0.5	0.8	1.7	1.3	0.2	1.3	0.7	-0.0	0.3	1.0	0.5	-0.6	0.0	1.2	0.6	1.3	1.3
Medication: Lisinopril	0.6	0.8	2.3	0.8	0.8	0.8	-0.1	1.0	1.3	0.6	-0.5	0.6	1.1	1.1	0.8	1.5	0.3
Medication: Atorvastatin	1.0	1.3	3.4	1.7	-0.2	1.3	0.5	0.6	-0.4	1.8	-0.1	-0.4	-0.1	1.8	1.3	1.3	1.4
Illnesses of father: High blood pressure	0.6	0.8	2.5	1.1	-0.7	0.4	0.0	0.1	-1.6	1.6	0.2	-0.7	-0.8	1.1	0.9	-0.3	1.1
Alcohol drinker status: Never	0.8	1.0	4.0	-0.8	0.3	-0.7	-0.9	-1.8	-0.8	-0.2	2.0	-1.4	-0.3	-0.0	-1.1	-0.5	-0.4
Ever smoked	0.9	1.6	5.5	-1.5	1.0	-0.8	-0.4	-2.0	0.3	-1.3	2.3	-0.8	0.3	-1.0	-1.8	-0.7	-0.9
Basal metabolic rate	0.2	1.3	6.5	0.6	-1.1	0.8	-0.9	1.1	-0.0	0.5	-2.0	-0.8	-0.5	1.3	0.8	2.5	0.4
Leg fat percentage (left)	0.3	0.9	2.8	1.3	-0.2	1.2	0.1	0.9	0.2	1.2	-0.6	-0.2	0.1	1.5	1.1	1.7	1.0
Arm fat-free mass (left)	0.3	1.7	8.5	0.8	-0.6	1.4	-0.3	1.4	0.6	0.9	-1.8	-0.4	-0.0	1.7	1.2	2.9	0.8
Number of operations (self-reported)	0.6	0.9	1.8	-0.6	-0.8	-0.8	-0.8	-1.2	-0.8	-1.2	0.3	-1.2	-1.1	-1.1	-1.3	-0.6	-0.6
Average weekly beer plus cider intake	1.0	1.4	8.6	1.2	-1.7	0.1	0.3	1.6	0.0	-1.0	-2.9	0.8	-0.9	-1.2	0.4	-0.1	-0.1
Irritability	2.1	3.5	10.3	-2.4	-0.4	-2.2	-0.8	-1.1	-0.0	-3.1	0.2	0.3	-0.5	-3.2	-2.2	-2.4	-2.3
Risk taking	2.0	3.0	10.8	-1.5	-0.6	-2.3	-0.9	-1.4	-1.5	-2.0	0.6	-0.2	-1.0	-2.6	-1.8	-3.3	-1.7
Ever had prostate specific antigen (PSA) test	2.2	2.5	6.4	1.5	-0.0	1.4	2.5	2.4	1.6	0.8	-1.9	2.5	0.7	-0.0	1.8	0.4	1.2
Fractured/broken bones in last 5 years	1.0	1.2	3.7	-0.3	-1.6	-0.4	0.4	-1.1	-1.4	-0.8	-0.0	-1.2	-1.9	-1.6	-0.9	-1.4	0.4
Age started oral contraceptive pill	0.2	0.3	0.8	-0.0	0.8	0.3	-0.2	0.0	0.5	0.5	0.5	0.0	0.7	0.9	0.3	0.7	0.1
Diastolic blood pressure, automated reading	1.3	4.1	8.7	2.9	-0.5	1.8	0.9	2.9	0.2	2.7	-2.5	1.1	0.3	2.4	3.0	1.9	1.8
Ever depressed for a whole week	1.1	1.4	5.2	-0.6	-0.9	-0.6	1.3	-1.2	-0.7	-1.2	0.7	-0.3	-1.2	-2.3	-1.2	-2.1	0.1
Unable to work because of sickness or disability	0.3	0.3	2.2	-0.6	0.5	0.3	0.1	-0.8	-0.0	0.5	1.5	-0.6	0.1	0.6	-0.2	0.2	0.4
Commuting to job workplace: Cycle	0.7	0.9	2.0	-1.2	0.2	-1.3	-1.4	-1.1	-0.9	-0.6	0.9	-0.7	-0.1	-0.3	-1.0	-0.8	-1.2
Myopia	0.7	1.0	2.8	-1.2	0.6	-1.2	-0.4	-0.2	0.5	-1.2	0.2	1.0	0.6	-1.4	-0.7	-1.7	-1.2
Vascular/heart problems diagnosed by doctor	0.7	1.9	4.4	-2.1	1.0	-1.5	-0.6	-1.6	0.2	-1.6	1.7	-0.1	0.5	-1.5	-1.8	-1.6	-1.5
Cholesterol lowering medication	0.3	0.4	1.6	0.3	0.4	0.4	-0.3	-0.8	-0.2	0.6	1.3	-1.0	0.0	0.9	-0.1	0.8	0.5
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	3.9	1.5	-1.5	1.3	1.2	1.4	-0.0	0.5	-2.0	0.1	-1.0	0.1	1.1	1.0	1.4
Pain experienced in last month	0.6	1.0	3.3	-1.2	-0.0	-1.0	-1.8	-1.4	-0.9	-0.5	0.8	-1.5	-0.4	0.1	-1.1	-0.0	-1.0
Supplements: Calcium	0.6	0.7	2.0	1.1	-0.7	1.1	0.6	0.0	0.0	0.6	-0.4	-0.9	-0.7	0.6	0.3	1.4	1.2
Basal cell carcinoma (self-reported)	0.6	0.7	1.9	-0.6	1.4	-0.5	0.1	0.1	1.1	-0.4	0.6	1.3	1.4	-0.3	-0.1	-0.6	-0.8
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.7	0.9	0.0	0.9	0.5	0.7	-0.1	1.3	-0.0	0.1	0.1	1.2	1.1	0.7	1.0
Deep venous thrombosis (DVT) (self-reported)	2.0	2.6	4.9	1.9	-1.3	1.9	1.9	2.1	0.0	1.6	-2.2	0.7	-0.7	0.9	2.0	1.1	2.1
Heart disease (siblings)	0.3	0.4	0.6	0.8	0.8	0.7	0.6	0.4	0.8	0.5	0.4	0.5	0.8	0.6	0.5	0.6	0.4
Alcohol drinker status: Previous	0.3	0.3	0.9	-0.0	-1.0	-0.4	-0.7	0.1	-0.8	-0.3	-0.8	-0.4	-0.8	-0.3	-0.1	-0.3	-0.2
Pack years of smoking	0.2	0.3	0.9	0.7	-0.6	0.1	0.0	-0.1	-0.9	0.7	-0.1	-0.5	-0.7	0.2	0.3	-0.4	0.6
Impedance of whole body	0.3	1.3	4.7	-0.8	1.1	-0.9	0.7	-1.1	0.4	-1.1	1.7	0.8	0.6	-1.6	-1.1	-2.2	-0.8
Leg fat mass (left)	0.4	1.5	5.8	1.3	-0.4	1.5	-0.0	1.2	0.3	1.4	-1.1	-0.4	0.0	1.9	1.4	2.4	1.2
Arm predicted mass (left)	0.2	1.2	6.9	0.4	-0.6	1.0	-0.6	1.1	0.5	0.6	-1.6	-0.5	-0.0	1.4	0.9	2.6	0.4