[Hub]/) : Traits : Lung FVC : ← →

chr17:17,017,584-18,325,085

Best TWAS P=8.77e-09 · Best GWAS P=6.77e-09 conditioned to 0.1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TOM1L2 0.19 0.24 bslmm 425 0.24 2.4e-29 -5.4 5.5 4.0e-08 -0.94 0.11 0.89 FALSE
2 GTEx Adipose Subcutaneous TOM1L2 0.04 0.04 lasso 3 0.04 5.3e-04 -5.5 5.4 7.6e-08 -0.96 0.05 0.94 FALSE
3 GTEx Adipose Visceral Omentum TOM1L2 0.15 0.13 lasso 4 0.11 3.6e-06 -5.4 5.6 2.4e-08 -0.97 0.04 0.96 FALSE
4 GTEx Cells Transformed fibroblasts SREBF1 0.09 0.01 lasso 11 0.01 3.2e-02 -5.6 -5.2 2.3e-07 0.85 0.06 0.72 FALSE
5 GTEx Muscle Skeletal TOM1L2 0.08 0.11 lasso 6 0.10 5.3e-10 -5.5 5.5 4.1e-08 -0.96 0.04 0.96 FALSE
6 GTEx Muscle Skeletal AC122129.1 0.13 0.14 lasso 4 0.13 7.3e-13 -5.8 5.7 1.2e-08 -0.99 0.04 0.96 FALSE
7 GTEx Whole Blood SREBF1 0.04 0.06 lasso 5 0.05 2.4e-05 -5.5 5.5 3.7e-08 -0.98 0.04 0.96 FALSE
8 ROSMAP Brain Pre-frontal Cortex TOM1L2 0.15 0.11 blup 414 0.10 1.4e-12 -5.5 5.8 8.8e-09 -0.86 0.05 0.95 TRUE
9 YFS Blood SREBF1 0.07 0.11 lasso 7 0.11 2.2e-33 -5.4 5.3 9.7e-08 -0.94 0.10 0.90 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma TOM1L2 0.01 0.01 blup 83 0.01 1.8e-03 -3.6 5.5 4.9e-08 -0.98 0.04 0.87 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LRRC48 0.07 0.05 enet 12 0.04 7.0e-03 -5.5 -5.3 1.3e-07 0.96 0.03 0.69 FALSE