[Hub]/) : Traits : Lung FVC : ← →

chr17:26,888,725-30,380,381

Best TWAS P=5.39e-13 · Best GWAS P=1.68e-26 conditioned to 3.34e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	GOSR1	0.16	0.14	blup	315	0.14	1.2e-16	-5.24	-5.5	3.2e-08	-0.31	1.00	0.00	FALSE
2	GTEx	Artery Aorta	CRLF3	0.12	0.03	enet	33	0.06	3.8e-04	-0.33	6.0	2.7e-09	0.53	0.25	0.70	FALSE
3	GTEx	Artery Tibial	GOSR1	0.09	0.08	enet	15	0.05	6.9e-05	-5.43	-5.2	2.1e-07	-0.36	0.92	0.01	FALSE
4	GTEx	Artery Tibial	RP11-848P1.7	0.54	0.00	lasso	10	0.02	7.3e-03	3.41	6.3	3.0e-10	0.47	0.02	0.06	FALSE
5	GTEx	Brain Cerebellum	CRLF3	0.52	0.12	lasso	27	0.20	1.3e-06	9.64	7.2	5.4e-13	0.56	0.09	0.74	TRUE
6	GTEx	Brain Cortex	GOSR1	0.20	0.20	enet	7	0.18	1.4e-05	-5.24	-5.8	7.1e-09	-0.34	0.83	0.03	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	EVI2A	0.13	0.03	lasso	4	0.01	1.5e-01	-4.56	5.3	1.0e-07	0.17	0.16	0.04	FALSE
8	GTEx	Esophagus Muscularis	SSH2	0.04	0.01	enet	10	0.00	3.3e-01	3.55	5.3	1.1e-07	0.18	0.51	0.06	TRUE
9	GTEx	Esophagus Muscularis	CRLF3	0.17	0.12	lasso	6	0.18	5.1e-11	-0.86	5.5	4.8e-08	0.46	0.94	0.05	FALSE
10	GTEx	Nerve Tibial	GOSR1	0.13	0.11	lasso	3	0.11	5.7e-08	-5.43	-5.4	6.1e-08	-0.35	0.99	0.00	FALSE
11	GTEx	Spleen	EVI2A	0.22	0.12	lasso	4	0.07	8.3e-03	-5.70	5.2	1.5e-07	0.17	0.11	0.05	FALSE
12	GTEx	Spleen	OMG	0.41	0.10	enet	26	0.08	4.5e-03	-4.66	-5.8	8.0e-09	-0.23	0.64	0.03	FALSE
13	GTEx	Whole Blood	EVI2A	0.07	0.04	lasso	4	0.04	2.6e-04	-5.44	5.2	1.6e-07	0.14	0.89	0.00	FALSE
14	METSIM	Adipose	NF1	0.04	0.00	blup	396	0.01	5.5e-03	-6.23	-5.7	1.5e-08	-0.30	0.80	0.02	FALSE
15	METSIM	Adipose	TEFM	0.08	0.06	blup	246	0.06	8.8e-10	10.65	5.9	3.9e-09	0.57	0.00	1.00	FALSE
16	YFS	Blood	EVI2A	0.03	0.05	lasso	4	0.04	1.0e-13	-5.70	5.7	1.2e-08	0.10	1.00	0.00	FALSE
17	YFS	Blood	NUFIP2	0.07	0.05	lasso	12	0.06	5.8e-19	-5.28	6.8	7.2e-12	0.13	0.01	0.99	TRUE
18	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EVI2A	0.03	0.03	blup	37	0.03	2.3e-03	-5.45	5.6	2.6e-08	0.10	0.02	0.79	FALSE
19	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	OMG	0.02	0.02	blup	31	0.02	3.2e-03	-5.39	5.4	8.1e-08	0.15	0.02	0.86	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	EVI2A	0.03	0.03	blup	38	0.03	6.9e-07	-5.46	5.2	2.1e-07	0.12	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	LRRC37B2	0.09	0.00	enet	11	0.03	7.3e-03	-4.82	6.9	5.8e-12	0.47	0.01	0.08	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	OMG	0.09	0.09	blup	31	0.11	2.0e-04	-4.51	5.2	2.1e-07	0.18	0.03	0.88	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EVI2A	0.04	0.00	blup	37	0.01	1.1e-02	-5.35	5.1	3.1e-07	0.00	0.01	0.52	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GOSR1	0.06	0.11	enet	7	0.10	6.8e-12	-5.43	-5.5	3.8e-08	-0.34	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	OMG	0.02	0.02	blup	31	0.03	6.9e-04	-4.57	5.2	1.6e-07	0.17	0.02	0.89	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	EVI2A	0.03	0.03	blup	38	0.04	3.0e-05	-5.49	5.4	7.5e-08	0.16	0.04	0.96	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	EVI2A	0.04	0.06	blup	38	0.06	3.0e-07	-5.53	5.5	4.3e-08	0.15	0.05	0.95	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EVI2A	0.03	0.03	lasso	1	0.02	2.4e-03	-5.55	5.5	2.9e-08	0.10	0.02	0.69	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	EVI2A	0.08	0.12	lasso	3	0.12	1.3e-12	-6.23	6.0	2.3e-09	0.12	0.01	0.99	TRUE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	GOSR1	0.02	0.00	blup	56	0.01	4.8e-02	-5.43	-5.3	1.2e-07	-0.34	0.01	0.74	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	EVI2A	0.05	0.03	enet	7	0.04	4.8e-04	-3.90	5.2	1.7e-07	0.13	0.04	0.64	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	GOSR1	0.07	0.08	lasso	3	0.07	2.1e-07	-5.30	-5.3	1.1e-07	-0.33	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	OMG	0.02	0.01	blup	32	0.02	4.8e-03	-4.66	5.3	9.7e-08	0.18	0.02	0.84	FALSE