Best TWAS P=1.97e-16 · Best GWAS P=7.11e-19 conditioned to 0.000198
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | MICAL3 | 0.23 | 0.06 | lasso | 4 | 0.03 | 2.7e-02 | 8.3 | -8.2 | 2.0e-16 | -0.82 | 0.11 | 0.19 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | MICAL3 | 0.12 | 0.04 | enet | 10 | 0.07 | 5.3e-06 | 7.9 | 5.5 | 4.6e-08 | 0.63 | 0.09 | 0.66 | FALSE |
| 3 | GTEx | Thyroid | MICAL3 | 0.18 | 0.13 | enet | 18 | 0.13 | 6.5e-10 | -5.1 | -6.5 | 1.0e-10 | -0.75 | 0.25 | 0.75 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MICAL3 | 0.10 | 0.06 | enet | 14 | 0.04 | 1.5e-03 | 8.8 | -8.2 | 3.0e-16 | -0.91 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | MICAL3 | 0.10 | 0.09 | enet | 14 | 0.10 | 1.4e-09 | -5.1 | -6.3 | 3.8e-10 | -0.71 | 0.27 | 0.73 | FALSE |