Best TWAS P=1.35e-12 · Best GWAS P=4.39e-12 conditioned to 0.0974
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CTA-85E5.10 | 0.10 | 0.04 | lasso | 9 | 0.03 | 1.9e-03 | 6.2 | -6.8 | 9.8e-12 | -0.78 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Adrenal Gland | RP1-130H16.16 | 0.21 | 0.03 | enet | 11 | 0.10 | 2.1e-04 | -4.0 | 5.9 | 3.5e-09 | 0.18 | 0.18 | 0.10 | FALSE |
| 3 | GTEx | Brain Cerebellum | CTA-85E5.10 | 0.13 | 0.09 | lasso | 4 | 0.02 | 1.1e-01 | -5.6 | 5.2 | 1.8e-07 | 0.24 | 0.10 | 0.23 | FALSE |
| 4 | GTEx | Testis | ZMAT5 | 0.09 | 0.08 | lasso | 2 | 0.05 | 2.3e-03 | -5.2 | 5.3 | 1.4e-07 | 0.24 | 0.23 | 0.05 | FALSE |
| 5 | GTEx | Testis | ASCC2 | 0.28 | 0.30 | lasso | 2 | 0.36 | 4.0e-17 | -5.2 | -5.2 | 1.6e-07 | -0.26 | 0.96 | 0.04 | FALSE |
| 6 | NTR | Blood | SEC14L4 | 0.01 | 0.01 | bslmm | 443 | 0.01 | 1.3e-03 | -3.8 | -5.1 | 3.1e-07 | -0.06 | 0.64 | 0.01 | TRUE |
| 7 | YFS | Blood | MTMR3 | 0.09 | 0.08 | lasso | 7 | 0.10 | 4.1e-32 | -4.7 | 6.8 | 1.5e-11 | 0.55 | 1.00 | 0.00 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | HORMAD2 | 0.06 | 0.04 | enet | 10 | 0.07 | 5.7e-07 | 6.2 | -7.1 | 1.3e-12 | -0.41 | 0.33 | 0.67 | TRUE |