[Hub]/) : Traits : Lung FVC : ← →

chr21:34,750,338-36,786,185

Best TWAS P=1.79e-13 · Best GWAS P=1.16e-14 conditioned to 0.000231

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CLIC6 0.10 0.14 lasso 2 0.13 1.7e-10 6.3 6.3 3.2e-10 -0.61 0.97 0.03 TRUE
2 GTEx Artery Tibial MRPS6 0.10 0.04 enet 4 0.00 1.2e-01 5.9 5.6 2.7e-08 0.14 0.02 0.82 TRUE
3 GTEx Pituitary CLIC6 0.56 0.31 lasso 4 0.33 4.9e-09 -6.9 -6.9 6.7e-12 0.60 0.71 0.27 FALSE
4 METSIM Adipose CLIC6 0.18 0.17 lasso 2 0.17 1.9e-24 6.3 6.1 1.1e-09 -0.62 0.97 0.03 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma CLIC6 0.01 0.01 lasso 1 0.01 2.2e-03 -6.2 6.2 4.8e-10 -0.54 0.10 0.56 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme CLIC6 0.20 0.00 blup 68 0.07 3.1e-03 -6.9 -6.5 1.1e-10 0.46 0.02 0.10 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma CLIC6 0.04 0.06 lasso 2 0.05 1.5e-06 -6.9 -6.9 6.3e-12 0.64 0.56 0.40 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma CLIC6 0.03 0.04 lasso 1 0.03 7.7e-05 -6.9 6.9 6.4e-12 -0.64 0.30 0.47 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma CLIC6 0.06 0.01 blup 68 0.03 5.7e-03 -7.5 7.4 1.8e-13 -0.76 0.02 0.60 TRUE