TWAS hub - C2orf42

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0580	0.0220	4.2e-04	0.058	0.023	0.045	0.049	0.052	1.3e-07	6.4e-04	3.4e-06	1.3e-06	5.1e-07
2	GTEx	Cells Transformed fibroblasts	0.1810	0.0450	9.8e-09	0.047	NA	0.140	NA	0.120	1.8e-04	NA	1.2e-10	NA	2.6e-09
3	GTEx	Lung	0.0747	0.0346	7.0e-03	0.013	NA	0.004	NA	0.017	3.0e-02	NA	1.5e-01	NA	1.6e-02
4	GTEx	Thyroid	0.0580	0.0250	7.5e-03	0.054	NA	0.035	NA	0.040	5.4e-05	NA	1.0e-03	NA	4.5e-04
5	METSIM	Adipose	0.0766	0.0217	4.3e-09	0.076	0.077	0.070	0.079	0.068	1.6e-11	1.5e-11	1.1e-10	6.4e-12	2.0e-10
6	TCGA	Breast Invasive Carcinoma	0.0285	0.0147	3.4e-05	0.018	0.022	0.021	NA	0.015	1.1e-04	1.8e-05	3.2e-05	NA	3.4e-04
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0580	0.0292	2.4e-05	0.040	0.041	0.030	NA	0.034	2.2e-05	2.0e-05	2.4e-04	NA	1.0e-04
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0820	0.0430	6.7e-04	0.080	0.063	0.068	NA	0.081	2.6e-05	1.8e-04	9.7e-05	NA	2.1e-05
9	TCGA	Brain Lower Grade Glioma	0.0304	0.0182	6.3e-03	-0.002	0.012	-0.002	NA	0.000	8.6e-01	1.3e-02	6.9e-01	NA	3.7e-01
10	TCGA	Lung Adenocarcinoma	0.0393	0.0214	3.9e-04	0.007	0.022	0.014	NA	0.009	4.8e-02	1.1e-03	8.0e-03	NA	2.5e-02
11	TCGA	Lung Squamous Cell Carcinoma	0.0460	0.0246	2.1e-04	0.004	0.026	0.022	NA	0.014	1.1e-01	4.9e-04	1.2e-03	NA	8.5e-03
12	TCGA	Soft Tissue Sarcoma	0.1220	0.0910	2.4e-03	0.031	0.041	0.046	NA	0.028	5.7e-03	1.7e-03	1.0e-03	NA	8.0e-03
13	TCGA	Thyroid Carcinoma	0.0640	0.0340	4.5e-05	0.043	0.045	0.049	NA	0.041	5.1e-05	3.1e-05	1.4e-05	NA	6.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Hearing aid user	8.1	9.2	12.2	-3.0	-3.0	-3.2	-3.1	-2.7	-3.5	-3.5	-2.9	-3.2	-2.9	-3.2	-1.4	-3.1
Pulse wave reflection index	5.9	7.2	10.0	2.5	2.5	2.8	2.6	2.1	3.1	3.2	2.6	3.0	2.6	3.2	1.8	2.6
Ever highly irritable/argumentative for 2 days	5.5	6.7	8.5	-2.7	-2.7	-2.4	-2.2	-2.1	-2.8	-2.8	-2.1	-2.6	-2.5	-2.8	-2.7	-2.9
Hair/balding pattern: Pattern 4	5.2	12.7	25.4	-1.8	-4.6	-3.7	-2.2	-2.8	-3.5	-3.1	-2.3	-3.4	-4.7	-3.8	-5.0	-3.6
Forced vital capacity (FVC)	4.9	18.9	37.3	3.7	5.6	4.6	4.1	3.9	3.6	3.4	4.3	3.4	4.7	4.1	6.1	4.2
Lung FVC	4.5	22.9	42.8	4.0	5.4	4.9	4.5	4.3	4.2	4.1	4.8	4.3	5.0	5.2	6.5	4.1
Neck or shoulder pain in last month	4.2	6.0	11.5	-3.4	-1.9	-1.8	-3.0	-2.9	-2.5	-2.7	-3.3	-1.4	-1.2	-2.0	-1.5	-2.9
Taking other prescription medications	3.7	5.7	7.6	-2.4	-1.9	-2.5	-2.6	-2.6	-2.7	-2.7	-2.5	-2.2	-1.9	-2.3	-1.6	-2.8
Forced vital capacity (FVC), Best measure	3.7	13.4	30.6	3.0	4.7	3.9	3.6	3.2	2.9	2.6	3.8	2.6	3.9	3.4	5.5	3.5
Number of self-reported non-cancer illnesses	3.7	6.4	7.8	-2.2	-2.8	-2.8	-2.5	-2.5	-2.5	-2.4	-2.5	-2.3	-2.6	-2.5	-2.7	-2.7
Age at First Birth	3.6	5.3	8.0	2.8	1.8	2.0	2.6	2.1	2.5	2.8	2.6	2.1	1.6	2.4	1.5	2.5
Forced expiratory volume in 1-second (FEV1)	3.6	12.1	24.2	2.9	4.2	3.7	3.1	3.1	3.1	2.9	3.3	3.0	3.7	3.5	4.9	3.4
Pain all over the body in last month	3.3	3.5	6.4	2.5	1.8	1.9	2.0	2.4	1.9	1.9	1.9	1.9	1.3	1.7	0.4	1.9
Alcohol intake frequency.	3.3	7.7	14.5	-1.9	-3.2	-3.0	-2.2	-2.0	-2.7	-2.6	-2.1	-3.0	-3.3	-3.1	-3.8	-2.4
Hand grip strength (left)	3.2	8.4	23.2	4.0	2.9	2.1	3.3	4.8	2.8	2.8	3.4	1.1	1.0	1.2	0.1	4.0
Alzheimer’s Disease (in father)	3.0	3.2	5.2	-2.0	-1.7	-1.6	-1.8	-2.0	-1.9	-1.9	-1.9	-1.3	-1.6	-1.5	-1.5	-2.3
Suffer from ‘nerves’	3.0	4.7	7.5	-2.1	-2.7	-2.1	-2.1	-1.9	-2.2	-2.3	-2.0	-2.2	-1.9	-2.2	-2.0	-2.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.8	8.8	19.4	2.3	3.7	3.1	2.8	2.5	2.5	2.3	3.0	2.3	3.2	2.9	4.4	2.9
Average weekly red wine intake	2.8	4.2	5.7	-2.1	-2.4	-2.3	-2.3	-2.3	-1.9	-1.8	-2.0	-2.0	-1.8	-1.8	-1.6	-2.0
Number of treatments/medications taken	2.7	4.8	8.5	-2.0	-1.9	-2.4	-2.2	-2.3	-2.4	-2.4	-2.1	-2.0	-2.1	-2.0	-1.5	-2.9
Loneliness, isolation	2.7	3.7	7.3	-0.6	-2.6	-2.3	-1.1	-1.2	-2.0	-1.8	-1.1	-2.0	-2.7	-2.1	-2.3	-1.9
Financial situation satisfaction	2.7	3.3	4.8	1.3	2.2	2.0	2.1	1.6	1.8	1.7	2.1	1.5	1.8	1.8	1.9	1.9
Schizophrenia (2014)	2.6	5.8	8.5	2.2	2.1	2.3	2.5	2.9	2.7	2.7	2.4	2.4	2.1	2.5	1.7	2.7
Smoking Status	2.6	6.3	8.7	2.4	1.7	2.3	2.7	2.6	2.6	2.8	2.6	2.7	2.0	2.9	3.0	2.1
Illnesses of mother	2.6	3.3	5.7	2.4	2.0	1.7	1.9	2.3	1.6	1.5	2.3	0.9	1.2	1.2	1.7	2.1
Past tobacco smoking	2.4	4.5	6.0	-2.1	-1.5	-2.0	-2.5	-2.2	-2.2	-2.3	-2.3	-2.2	-1.6	-2.2	-2.3	-1.9
Time employed in main current job	2.4	2.7	5.1	-0.7	-1.4	-1.8	-1.2	-0.9	-1.8	-1.9	-1.0	-2.2	-2.1	-2.3	-2.0	-1.1
Handedness (chirality/laterality): Left-handed	2.4	2.9	5.9	1.7	1.6	1.6	1.6	2.2	1.8	1.7	1.5	1.2	1.9	1.4	1.3	2.4
High cholesterol (Self-reported)	2.4	4.3	8.9	-1.5	-3.0	-2.6	-1.8	-1.7	-1.6	-1.1	-2.0	-0.9	-2.6	-1.2	-2.8	-2.7
Basal cell carcinoma (self-reported)	2.4	2.9	5.4	-2.3	-0.8	-1.3	-1.9	-2.0	-2.0	-2.2	-1.8	-1.4	-1.2	-1.8	-0.4	-1.9
Angina	2.3	3.0	6.0	-2.4	-1.2	-1.4	-2.0	-1.6	-2.1	-2.2	-1.9	-1.4	-1.0	-1.5	-0.6	-2.4
Financial difficulties in last 2 years	2.3	3.1	4.8	-1.2	-2.2	-2.1	-1.8	-1.4	-1.7	-1.7	-1.9	-1.3	-2.1	-1.6	-1.7	-2.0
Depression (self-reported)	2.3	2.8	7.5	-1.4	-2.4	-1.6	-1.6	-1.4	-1.2	-1.0	-1.9	-0.5	-1.6	-1.1	-2.7	-2.0
Smoking status: Previous	2.3	3.4	6.8	1.6	1.7	1.7	2.1	1.8	1.8	1.8	2.1	1.6	1.4	1.8	2.6	1.8
Depression (Nagel 2018)	2.2	3.4	6.0	-0.7	-2.1	-2.0	-1.1	-1.3	-1.8	-1.7	-1.0	-2.4	-2.5	-2.4	-2.4	-1.2
Prostate Cancer	2.2	3.1	6.4	1.2	2.2	2.0	1.3	1.3	1.7	1.3	1.6	1.1	2.5	1.7	2.1	2.0
LDL Cholesterol	2.2	3.6	12.0	-0.7	-2.5	-2.1	-1.2	-1.4	-1.3	-1.2	-1.0	-1.9	-2.5	-2.1	-3.5	-1.1
Had menopause	2.2	2.7	5.9	-1.1	-1.9	-2.0	-1.2	-1.5	-1.7	-1.4	-1.3	-1.5	-2.4	-1.6	-1.4	-1.9
Medication: Bendroflumethiazide	2.2	3.3	6.5	-1.4	-2.5	-1.9	-1.4	-1.4	-1.6	-1.4	-1.5	-2.0	-2.2	-2.1	-2.3	-1.3
Medication: Co-codamol	2.1	2.4	5.2	-1.8	-0.9	-1.4	-2.3	-1.4	-1.9	-2.0	-2.1	-1.3	-0.5	-1.2	-0.4	-1.8
Eye problems/disorders: None of the above	2.1	2.4	4.7	2.2	1.3	1.3	1.6	1.4	1.8	2.0	1.7	1.4	1.1	1.6	-0.0	1.6
Angina (self-reported)	2.1	2.8	5.6	-2.2	-1.0	-1.3	-1.8	-1.5	-2.1	-2.2	-1.6	-1.4	-1.0	-1.5	-0.5	-2.4
Asthma (self-reported)	2.1	4.1	5.4	-0.9	-2.2	-2.3	-2.0	-1.6	-2.1	-2.0	-1.9	-2.3	-2.3	-2.3	-2.3	-1.8
Myopia	2.1	3.0	4.0	1.6	2.0	1.7	1.7	1.4	1.8	1.8	1.9	1.4	1.8	1.8	1.6	2.0
Bipolar Disorder (2011)	2.0	1.9	4.9	2.1	1.0	0.7	2.0	1.9	1.1	1.3	2.2	0.2	0.1	0.6	0.5	1.8
Asthma	2.0	3.9	5.0	-1.1	-2.2	-2.2	-2.1	-1.6	-2.0	-1.9	-1.9	-2.1	-2.1	-2.1	-2.2	-1.9
Long-standing illness, disability or infirmity	2.0	3.0	6.2	-2.5	-1.3	-1.5	-2.3	-2.5	-1.6	-1.6	-2.4	-0.6	-0.5	-0.9	-0.7	-2.1
Lupus	1.9	2.9	8.2	-1.1	-2.4	-1.8	-1.5	-1.1	-1.2	-1.1	-1.8	-1.1	-2.1	-1.6	-2.9	-1.2
Chronic bronchitis/emphysema (father)	1.9	2.3	4.1	1.0	1.4	1.8	1.6	0.6	1.6	1.6	1.3	2.0	1.6	1.9	1.4	1.0
Alcohol drinker status: Previous	1.9	2.1	3.0	-1.2	-1.2	-1.6	-1.4	-1.2	-1.7	-1.7	-1.2	-1.7	-1.6	-1.5	-0.8	-1.7
Mouth/teeth dental problems	1.8	2.7	4.0	1.7	2.0	1.8	1.9	1.5	1.6	1.7	1.9	1.6	1.4	1.8	0.8	1.2
Worry too long after embarrassment	1.8	3.1	7.0	-0.4	-2.6	-2.2	-0.8	-0.4	-1.7	-1.4	-0.9	-2.0	-2.5	-1.8	-2.3	-1.6
Ever had bowel cancer screening	1.8	2.1	4.5	-1.1	-0.7	-1.4	-1.2	-0.9	-1.9	-2.0	-1.1	-2.1	-1.4	-2.0	-1.0	-1.1
Commuting to job workplace: Cycle	1.8	2.2	10.1	0.6	1.7	1.4	0.9	1.0	1.0	0.9	1.1	0.6	2.0	1.2	3.2	1.6
Ever smoked	1.7	2.9	4.5	2.1	1.0	1.7	2.1	1.8	1.8	1.9	1.9	1.7	1.2	1.8	1.2	1.6
Hand grip strength (right)	1.6	4.3	14.3	3.0	1.7	1.1	2.4	3.8	2.0	2.0	2.5	0.7	0.3	0.8	0.0	2.8
Mouth/teeth dental problems: Loose teeth	1.6	1.9	4.4	-0.7	-1.6	-1.4	-1.0	-0.6	-1.3	-1.3	-0.8	-2.1	-1.6	-2.1	-1.8	-0.3
Qualifications: nursing, teaching	1.6	2.5	8.7	0.2	2.5	1.7	0.9	0.8	1.2	0.9	1.0	1.3	2.1	1.5	3.0	1.3
Average weekly champagne plus white wine intake	1.6	2.2	9.5	0.5	1.5	1.2	1.1	1.1	1.2	1.2	1.2	1.2	1.7	1.8	3.1	1.1
Bipolar Disorder or Schizophrenia	1.5	3.6	5.2	1.9	1.4	1.9	2.2	2.2	2.2	2.2	2.0	1.8	1.5	1.9	0.9	2.3
Reaction Time	1.5	2.9	4.8	-2.2	-1.4	-1.4	-2.2	-2.1	-1.7	-2.0	-2.2	-1.4	-0.6	-1.4	-1.2	-1.6
Verbal and Numeric Reasoning (VNR)	1.5	3.5	11.8	1.5	2.4	1.6	1.7	1.2	1.4	1.4	1.6	1.8	1.9	1.9	3.4	1.4
Fasting Glucose	1.5	1.8	2.9	-1.3	-1.2	-1.0	-1.4	-1.7	-1.4	-1.5	-1.4	-1.2	-0.9	-1.5	-1.3	-1.2
Respiratory disease	1.5	3.3	6.4	-0.6	-2.3	-2.0	-1.1	-1.0	-1.9	-1.7	-1.0	-2.0	-2.5	-1.9	-2.4	-1.9
Qualifications: A levels/AS levels or equivalent	1.5	3.3	9.3	1.5	2.5	1.6	1.6	1.2	1.5	1.4	1.8	1.3	1.9	1.7	3.0	1.7
Peak expiratory flow (PEF)	1.5	3.4	6.7	1.8	1.9	1.8	1.6	1.6	1.8	1.9	1.4	2.1	1.7	2.2	2.6	1.5
Health satisfaction	1.5	1.9	3.9	2.0	1.6	1.1	1.8	1.8	1.0	1.0	1.8	0.9	0.6	1.1	1.3	1.1
Medication: Blood pressure	1.5	2.8	4.9	-2.2	-2.2	-1.2	-1.6	-2.0	-1.3	-1.3	-1.9	-1.0	-1.3	-1.7	-2.2	-1.4
Schizophrenia (2018)	1.4	2.8	4.3	1.4	1.2	1.7	1.9	1.8	2.0	2.1	1.7	1.8	1.4	1.8	0.5	1.8
Hair/balding pattern: Pattern 3	1.4	2.1	4.9	1.7	0.1	0.8	1.7	1.9	1.8	2.2	1.2	1.9	0.0	1.4	-1.2	1.1
Unable to work because of sickness or disability	1.4	1.8	5.6	-2.4	-1.4	-0.8	-1.4	-2.3	-1.2	-1.3	-1.5	-0.7	-0.2	-0.6	-0.1	-1.6
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	4.2	1.5	1.5	0.8	1.3	1.5	1.0	1.0	1.5	0.6	0.9	1.0	2.0	1.4
Townsend deprivation index at recruitment	1.3	1.8	3.6	-1.6	-1.3	-1.3	-1.2	-1.9	-1.3	-1.3	-1.3	-1.1	-1.1	-1.2	-1.3	-1.5
Mean time to correctly identify matches	1.3	2.4	5.1	-2.2	-1.3	-1.2	-2.0	-1.9	-1.5	-1.7	-2.1	-0.8	-0.4	-1.1	-0.9	-1.8
Hypertension (Self-reported)	1.3	3.7	8.7	-1.4	-2.2	-2.0	-1.5	-1.3	-1.7	-1.6	-1.7	-1.8	-2.3	-2.2	-2.9	-1.7
Commuting to job workplace: Public transport	1.3	1.5	3.6	1.3	1.4	0.7	1.3	1.3	0.9	1.1	1.5	0.9	0.7	1.5	1.9	0.7
Age started oral contraceptive pill	1.3	1.6	3.6	-1.2	0.7	-0.9	-1.1	-1.9	-1.5	-1.8	-0.8	-1.7	-0.2	-1.2	1.5	-0.8
Triglycerides	1.2	2.0	3.7	-1.6	-1.9	-1.4	-1.9	-1.8	-1.0	-1.0	-1.9	-0.5	-0.8	-0.6	-0.9	-1.9
Cardiovascular Disease	1.2	4.0	13.4	-1.8	-2.8	-2.2	-1.7	-1.6	-1.2	-0.9	-2.1	-1.1	-2.0	-1.5	-3.7	-1.8
High blood pressure	1.2	3.2	9.2	-1.3	-2.1	-1.8	-1.3	-1.1	-1.5	-1.4	-1.5	-1.6	-2.2	-2.0	-3.0	-1.4
Had other major operations	1.2	1.5	2.6	-1.5	-1.6	-1.3	-1.5	-1.1	-0.9	-0.9	-1.4	-1.1	-0.9	-1.1	-1.3	-0.6
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.8	1.4	1.0	1.0	0.8	1.0	1.2	1.2	1.0	1.0	1.3	1.2	1.7	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	3.8	1.0	1.8	1.9	1.4	1.0	1.6	1.5	1.4	1.9	1.7	1.8	2.0	1.2
Worry (Nagel 2018)	1.1	2.3	6.0	-0.8	-1.8	-1.4	-0.9	-0.6	-1.8	-1.8	-0.6	-2.4	-1.6	-2.1	-1.7	-1.1
Blood White Count	1.1	7.9	22.9	-1.2	-1.6	-3.0	-1.5	-1.6	-3.8	-4.0	-0.9	-4.8	-3.2	-3.9	-0.5	-2.0
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	1.9	0.9	1.1	1.1	1.0	1.4	1.1	1.0	1.1	1.1	1.0	1.2	1.4	1.0
Fed-up feelings	1.1	2.0	6.6	0.5	-1.9	-1.3	-0.2	-0.3	-1.3	-1.0	-0.2	-1.4	-2.2	-1.5	-2.6	-1.2
Neuroticism score	1.1	2.4	5.8	-0.4	-2.2	-1.6	-0.6	-0.1	-1.6	-1.4	-0.7	-1.6	-2.1	-1.8	-2.4	-1.4
Shortness of breath walking on level ground	1.1	1.3	2.6	1.6	1.0	0.9	1.5	1.2	1.2	1.5	1.4	1.1	0.5	1.3	0.3	0.7
Age at last live birth	1.1	1.6	4.0	2.0	1.1	1.1	1.3	1.2	1.4	1.5	1.3	1.3	0.6	1.2	0.6	1.2
Primary Biliary Cirrhosis	1.0	1.4	3.2	-1.5	-1.8	-1.1	-1.4	-0.8	-0.8	-0.7	-1.7	-0.1	-1.0	-0.6	-1.3	-1.5
Allergy or Eczema	1.0	2.7	4.7	-1.8	-0.9	-1.4	-1.6	-1.7	-1.9	-2.1	-1.3	-2.1	-1.2	-2.2	-1.3	-1.3
Frequency of depressed mood in last 2 weeks	1.0	1.3	4.3	-0.7	-1.7	-1.1	-0.7	-1.1	-0.9	-0.8	-0.8	-0.9	-1.4	-1.1	-2.1	-0.9
Hayfever, allergic rhinitis or eczema	1.0	2.2	4.8	-1.8	-0.3	-1.0	-1.6	-1.5	-1.9	-2.2	-1.2	-2.0	-0.7	-2.0	-0.7	-1.1
High blood pressure (mother)	1.0	1.5	3.3	-1.8	-1.8	-0.7	-1.3	-1.5	-0.8	-0.8	-1.6	-0.3	-0.5	-0.7	-1.5	-1.2
Falls in the last year	1.0	1.4	2.9	-0.8	-0.9	-1.1	-0.7	-0.9	-1.2	-1.3	-0.6	-1.7	-1.3	-1.6	-1.5	-0.6
Mouth/teeth dental problems: Dentures	1.0	1.6	2.7	-1.4	-1.3	-1.4	-1.1	-1.0	-1.3	-1.3	-1.1	-1.7	-1.2	-1.6	-1.3	-0.8
Medication: Lansoprazole	1.0	1.1	2.9	-0.7	-1.6	-1.2	-1.1	-1.0	-0.5	-0.4	-1.4	-0.0	-1.2	-0.5	-1.7	-1.1
Gout (self-reported)	1.0	1.4	3.8	0.2	1.6	1.5	0.8	0.6	1.1	0.8	0.7	0.9	2.0	1.0	1.6	1.3
Age at first live birth	1.0	1.7	3.2	1.8	1.6	1.2	1.2	1.1	1.2	1.1	1.4	0.8	1.1	1.1	1.6	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.5	-0.7	-1.6	-1.2	-0.8	-0.7	-1.0	-0.8	-1.0	-0.7	-1.4	-0.8	-1.2	-1.2
Friendships satisfaction	1.0	1.2	2.6	0.9	1.3	1.3	1.0	1.0	1.0	1.0	0.8	1.6	1.1	1.4	1.1	0.3
Osteoarthritis (self-reported)	1.0	1.4	4.2	-1.5	-0.6	-0.5	-1.7	-2.1	-1.0	-1.2	-1.8	-0.2	0.1	-0.5	0.0	-1.3
Medication: Gliclazide	1.0	1.2	2.7	-0.4	-1.1	-1.0	-0.3	-0.7	-1.1	-1.1	-0.4	-1.2	-1.6	-1.5	-1.5	-0.9
Eye problems/disorders: Glaucoma	1.0	1.2	2.5	-1.4	-0.8	-0.9	-1.3	-1.6	-1.1	-1.2	-1.4	-0.6	-0.7	-1.1	0.1	-1.1
Average weekly beer plus cider intake	1.0	1.5	3.6	1.6	0.9	1.3	1.9	1.7	0.8	0.8	1.9	0.3	0.2	0.3	0.5	1.4
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.6	-1.1	-0.3	-0.8	-1.4	-1.1	-1.4	-1.6	-1.2	-1.2	-0.5	-1.3	0.1	-1.1
Vascular/heart problems diagnosed by doctor	1.0	2.8	5.5	1.7	1.8	1.7	1.4	1.3	1.5	1.4	1.6	1.5	1.8	1.7	2.3	1.6
Neuroticism (2016)	0.9	1.2	3.9	0.6	-1.8	-1.2	0.0	0.6	-1.0	-0.6	-0.2	-1.1	-2.0	-1.0	-1.3	-1.2
Rheumatoid Arthritis	0.9	1.2	5.1	0.5	-1.5	-1.4	0.2	-0.6	-0.4	0.1	0.0	-0.6	-2.1	-0.7	-2.2	-0.5
Supplements: Zinc	0.9	1.0	3.8	-1.3	-0.6	-0.4	-1.0	-0.8	-0.8	-1.0	-1.0	-0.9	-0.4	-1.2	-1.9	-0.7
Diabetes (mother)	0.9	1.1	2.6	1.4	-0.4	-0.1	1.6	1.4	0.4	0.6	1.6	-0.3	-1.3	-0.2	-1.6	0.5
Medication: Atenolol	0.9	1.2	4.3	0.3	-1.2	-1.1	0.0	-0.4	-1.0	-0.8	-0.1	-1.1	-2.1	-1.4	-1.6	-0.9
Headache pain in last month	0.9	1.6	3.1	-0.6	-1.8	-1.7	-1.3	-0.7	-1.2	-1.1	-1.2	-1.1	-1.8	-1.1	-0.8	-1.6
Medication: Ventolin 100micrograms inhaler	0.9	1.2	1.8	-0.9	-0.5	-0.9	-1.3	-0.9	-1.3	-1.4	-1.1	-1.3	-0.8	-1.3	-1.2	-1.1
Wheeze or whistling in the chest in last year	0.9	1.6	3.7	-1.6	-0.9	-0.8	-1.9	-1.4	-1.2	-1.5	-1.9	-1.1	-0.2	-1.3	-0.6	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	3.1	-1.5	-0.5	-0.4	-1.8	-1.6	-0.5	-0.7	-1.5	-0.2	0.9	0.1	0.9	-0.9
Smoking status: Current	0.9	1.4	3.0	1.5	-0.0	0.8	1.4	1.6	1.3	1.7	1.2	1.6	0.3	1.5	-0.3	0.5
Medication: Atorvastatin	0.9	1.2	2.3	-0.9	-1.2	-1.3	-0.6	-0.8	-0.9	-0.8	-0.5	-1.2	-1.5	-1.1	-1.5	-1.1
Risk taking	0.9	1.4	2.9	0.6	0.8	1.2	0.8	0.7	1.2	1.2	0.6	1.7	1.4	1.5	1.7	0.9
Ever depressed for a whole week	0.9	1.1	3.1	-0.3	-1.3	-1.1	-0.3	-0.5	-1.0	-0.9	-0.3	-0.8	-1.8	-1.2	-1.6	-1.1
Cholesterol lowering medication	0.9	1.4	2.9	-1.1	-1.4	-1.1	-0.9	-0.9	-1.0	-0.9	-1.2	-0.4	-1.5	-0.9	-1.7	-1.6
Supplements: Calcium	0.9	1.0	2.1	-0.6	0.3	-1.0	-0.6	-1.1	-1.5	-1.4	-0.3	-1.3	-1.0	-0.8	1.0	-1.4
Depressed Affect (Nagel 2018)	0.8	1.6	3.1	-0.2	-1.7	-1.6	-0.7	-0.6	-1.3	-1.3	-0.6	-1.5	-1.8	-1.5	-1.5	-1.1
Major Depression (MDD)	0.8	1.0	2.5	-0.2	-1.6	-1.6	-0.8	-0.7	-0.7	-0.3	-0.8	-0.7	-1.3	-0.7	-1.4	-0.9
Breast Cancer	0.8	2.0	7.0	1.0	-0.6	-1.4	0.7	1.4	-0.9	-0.4	0.7	-1.8	-2.6	-1.6	-2.5	-0.2
Body Mass Index (BMI) (2010)	0.8	1.1	1.8	1.2	1.1	1.2	1.3	0.7	1.0	1.1	1.3	1.1	0.8	1.0	0.9	1.0
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.2	-1.5	-1.1	-0.6	-1.0	-0.4	-0.7	-0.8	-0.9	-0.7	-0.7	-1.0	-1.2	-0.8
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	4.5	-0.1	-0.4	-0.4	0.5	0.5	-0.8	-0.9	0.3	-1.0	-1.6	-1.5	-2.1	-0.3
Father’s age at death	0.8	1.1	2.2	-0.8	-0.6	-1.1	-1.0	-1.4	-1.1	-1.2	-0.9	-1.5	-0.9	-1.4	-0.5	-0.5
Noisy workplace	0.8	1.0	2.6	0.1	1.1	1.5	0.6	0.5	0.9	0.8	0.8	1.1	1.6	1.2	1.3	0.7
Birth weight	0.8	1.7	6.8	1.2	1.3	1.1	0.7	1.2	1.1	0.9	0.7	0.9	1.5	1.1	2.6	1.4
High blood pressure (siblings)	0.8	1.2	1.7	1.1	0.6	1.3	1.1	1.3	1.2	1.2	1.1	1.0	1.1	1.0	0.8	1.2
Emphysema/chronic bronchitis	0.8	0.9	2.5	1.0	0.4	0.5	1.0	0.9	1.1	1.4	0.9	1.3	0.5	1.6	0.6	0.3
Guilty feelings	0.8	1.2	3.9	1.5	0.6	0.8	1.2	2.0	1.0	1.0	1.2	0.4	0.7	0.5	-0.0	1.6
Mother’s age at death	0.8	1.0	2.4	-1.5	-0.6	-0.8	-0.9	-1.3	-1.1	-1.3	-1.0	-1.0	-0.6	-1.0	-0.1	-0.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.5	-1.6	-0.6	-0.8	-1.4	-0.8	-1.1	-1.2	-1.3	-0.6	-0.4	-0.7	-0.0	-1.2
Intelligence (Savage-Jansen 2018)	0.7	2.0	6.0	1.5	1.6	0.8	1.4	1.2	1.2	1.4	1.6	1.1	1.0	1.5	2.4	1.2
Blood Platelet Count	0.7	8.6	34.6	-3.1	2.6	2.4	-2.0	-3.5	0.5	-0.4	-1.8	1.8	5.3	2.0	5.9	0.3
Hypothyroidism (self reported)	0.7	1.7	6.4	-0.6	-1.9	-1.5	-0.8	-1.2	-0.9	-0.5	-0.9	-1.0	-1.6	-0.9	-2.5	-1.1
Medication for hormone replacement therapy	0.7	0.7	1.4	0.6	0.8	1.1	0.7	1.0	0.7	0.7	0.6	1.2	0.9	1.1	1.1	0.3
Trunk fat percentage	0.7	2.8	7.8	-0.7	-2.5	-2.2	-1.0	-0.8	-1.4	-1.2	-1.2	-1.3	-2.8	-1.5	-1.7	-1.8
Current tobacco smoking	0.7	1.2	2.5	1.4	-0.1	0.6	1.2	1.5	1.2	1.6	1.1	1.3	0.2	1.4	-0.3	0.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.3	-0.4	-0.7	-0.8	-1.2	-0.4	-0.8	-0.8	-1.1	-0.8	-0.7	-1.0	-1.5	-0.7
Nervous feelings	0.7	1.3	2.3	-1.2	-1.2	-0.9	-0.7	-0.8	-1.2	-1.2	-0.6	-1.5	-1.0	-1.3	-1.4	-0.9
Allergy	0.7	1.6	3.0	1.5	0.4	0.9	1.5	1.3	1.6	1.7	1.2	1.6	0.3	1.4	0.7	1.1
Fluid intelligence score	0.7	1.4	4.5	1.1	1.7	0.9	1.1	1.0	0.8	0.7	1.0	1.0	1.1	1.0	2.1	1.1
Length of working week for main job	0.7	0.8	1.9	-0.3	-1.1	-0.9	-0.3	-0.6	-1.1	-1.0	-0.3	-1.1	-1.4	-1.2	-0.8	-0.9
Leg fat percentage (right)	0.7	2.5	7.5	-0.5	-2.5	-1.9	-1.0	-0.2	-1.0	-0.7	-1.2	-0.7	-2.5	-1.2	-2.7	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.3	0.7	0.9	1.1	1.0	0.7	1.0	0.8	1.0	1.0	1.0	0.9	1.1	0.8
Qualifications: College or University degree	0.7	2.1	9.9	0.5	2.3	1.3	0.8	-0.4	0.9	0.7	1.0	0.9	2.0	1.4	3.2	1.0
Number of full sisters	0.7	0.9	3.1	1.8	-0.5	-0.1	1.1	1.4	0.5	0.9	1.1	0.0	-0.9	0.2	-1.1	0.5
Overall health rating	0.7	1.4	4.5	-0.4	-1.5	-1.1	-1.0	-1.1	-1.0	-1.0	-1.3	-0.6	-1.3	-1.1	-2.1	-1.2
Mood swings	0.7	1.2	5.0	0.4	-1.3	-1.0	-0.2	0.3	-1.0	-0.9	-0.5	-0.6	-1.8	-1.1	-2.2	-1.2
Commuting to job workplace: Walk	0.7	0.7	1.7	0.6	0.7	0.9	1.2	0.6	0.8	0.6	1.3	0.2	0.4	0.4	1.2	1.2
Mineral and other dietary supplements	0.7	1.0	2.4	0.3	0.6	0.8	0.3	0.6	1.1	1.1	0.3	1.2	1.4	1.4	1.6	0.7
Bipolar Disorder (2018)	0.6	1.0	1.8	1.3	0.6	0.8	1.2	1.3	0.9	0.9	1.1	0.6	0.7	0.7	0.8	1.4
Neuroticism (Nagel 2018)	0.6	1.5	3.2	0.2	-1.8	-1.3	-0.4	0.1	-1.3	-1.1	-0.2	-1.8	-1.7	-1.5	-1.5	-0.9
Blood Red Count	0.6	6.1	24.5	-1.4	3.6	3.4	-0.5	-0.7	1.7	0.8	-0.5	2.6	4.9	2.2	3.2	1.5
Chronotype (morning person)	0.6	1.4	4.7	-1.2	-1.3	-0.7	-1.5	-1.0	-0.8	-0.9	-1.3	-1.2	-0.4	-1.3	-2.2	-0.4
Sensitivity / hurt feelings	0.6	1.0	2.2	1.3	-0.8	-1.0	1.1	1.5	-0.5	-0.2	1.2	-1.2	-1.5	-0.4	-0.2	-0.2
Hearing difficulty/problems: Yes	0.6	0.9	3.1	-1.2	-1.5	-0.8	-0.9	-1.0	-0.2	-0.1	-1.3	0.2	-0.5	-0.3	-1.8	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	1.9	-0.5	-0.9	-0.8	-0.4	-0.5	-1.0	-1.0	-0.4	-1.3	-1.2	-1.4	-1.3	-0.5
Body mass index (BMI)	0.6	2.6	6.9	-0.9	-2.6	-2.1	-1.4	-0.5	-1.0	-0.7	-1.6	-0.9	-2.2	-1.4	-2.6	-1.4
Number of incorrect matches in round	0.6	0.9	3.5	-0.5	1.1	1.6	0.2	-0.2	1.0	0.6	0.2	1.2	1.9	0.9	0.3	0.8
Breastfed as a baby	0.6	0.8	6.5	0.5	0.7	0.3	0.3	0.6	0.4	0.4	0.8	-0.0	0.8	0.8	2.6	0.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.7	-0.7	-0.7	-0.8	-0.8	-1.0	-1.1	-0.9	-1.0	-0.5	-0.5	-0.6	-0.4	-1.3
Body fat percentage	0.6	2.3	7.1	-0.4	-2.5	-2.0	-0.8	-0.3	-1.1	-0.8	-1.1	-0.9	-2.7	-1.2	-1.9	-1.6
Comparative body size at age 10	0.6	1.6	4.3	2.0	1.1	1.1	1.7	2.1	1.1	0.9	1.7	0.4	-0.0	0.1	0.1	1.8
Medication for pain relief, constipation, heartburn	0.6	1.0	2.7	1.4	0.8	0.8	1.6	1.0	0.8	0.7	1.5	0.2	-0.1	-0.0	-0.2	1.4
Heart disease (mother)	0.6	0.7	1.9	-1.3	-0.7	-0.5	-1.3	-0.8	-0.7	-0.8	-1.4	-0.2	-0.0	-0.5	-0.6	-0.8
Whole body fat mass	0.6	2.4	5.9	-0.7	-2.2	-2.1	-1.1	-0.6	-1.3	-1.2	-1.2	-1.4	-2.4	-1.6	-1.6	-1.4
Leg fat mass (right)	0.6	2.3	5.2	-0.7	-2.1	-1.9	-1.2	-0.5	-1.2	-1.1	-1.4	-1.2	-2.3	-1.6	-2.1	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.2	-0.8	-1.5	-1.2	-1.0	-0.4	-0.3	-0.1	-0.9	-0.6	-0.5	-0.1	-1.3	-0.6
Illnesses of father: Heart disease	0.6	0.9	2.2	-1.5	-0.5	-0.4	-1.4	-1.2	-0.9	-1.1	-1.3	-0.5	0.2	-0.7	-0.2	-0.9
Arm fat mass (left)	0.6	2.3	5.2	-0.8	-2.1	-2.1	-1.2	-0.5	-1.3	-1.1	-1.4	-1.3	-2.3	-1.6	-1.6	-1.3
Wears glasses or contact lenses	0.6	0.7	1.0	0.9	0.8	0.7	0.8	1.0	0.8	0.8	0.9	0.8	0.8	1.0	1.0	0.6
Leg fat percentage (left)	0.6	2.0	6.7	-0.2	-2.4	-1.7	-0.7	0.1	-0.7	-0.3	-0.9	-0.5	-2.4	-0.9	-2.6	-1.4
Pain experienced in last month	0.6	1.0	2.4	0.7	1.4	1.0	1.2	0.4	0.8	0.7	1.4	0.1	1.0	0.5	1.0	1.5
Alzheimer’s Disease (including proxy)	0.5	0.8	2.0	-0.9	-0.6	-0.8	-0.7	-0.9	-0.9	-1.0	-0.8	-0.3	-1.1	-0.8	-0.7	-1.4
Crohns Disease (2012)	0.5	0.8	3.0	1.6	1.3	0.5	1.1	1.7	0.4	0.4	1.1	0.0	0.1	0.1	-0.5	0.6
Hair Pigment	0.5	14.4	40.8	-0.5	-5.0	-4.7	-1.5	-1.8	-3.4	-2.5	-1.9	-3.1	-6.4	-3.7	-5.9	-3.9
Relative age of first facial hair	0.5	1.1	1.7	-1.3	-0.7	-0.6	-1.0	-1.3	-1.0	-1.2	-0.9	-1.3	-0.4	-1.3	-1.2	-0.5
Relative age voice broke	0.5	0.8	1.6	-0.6	-1.2	-1.0	-1.1	-1.3	-0.7	-0.7	-1.0	-1.0	-0.6	-0.9	-0.5	-0.5
Trunk fat mass	0.5	1.9	5.1	-0.6	-1.9	-1.9	-0.9	-0.6	-1.3	-1.2	-1.0	-1.5	-2.3	-1.5	-1.1	-1.3
Hair/balding pattern: Pattern 2	0.5	0.6	2.3	-0.8	0.1	-0.6	-0.8	-0.1	-1.0	-1.2	-0.4	-1.5	0.1	-0.8	0.8	-0.3
Alcohol intake versus 10 years previously	0.5	0.8	4.6	-0.0	-1.1	-0.7	-0.4	-0.3	-0.4	-0.4	-0.6	-0.3	-1.3	-0.9	-2.1	-0.5
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	0.3	0.3	0.7	0.7	-0.2	0.8	0.9	0.7	0.9	0.9	1.2	1.2	0.3
Arm fat mass (right)	0.5	2.2	4.6	-0.9	-2.1	-2.0	-1.3	-0.6	-1.3	-1.1	-1.4	-1.3	-2.1	-1.6	-1.5	-1.3
Pulse wave peak to peak time	0.5	0.6	1.7	-0.3	-0.1	-0.6	-0.7	0.2	-0.8	-1.0	-0.6	-1.0	-0.8	-1.3	-0.9	-0.2
Medication: Blood pressure	0.5	0.9	2.2	-0.6	-1.0	-1.3	-0.7	-0.6	-1.0	-0.9	-0.6	-1.0	-1.3	-0.7	-0.8	-1.5
Migraine (self-reported)	0.5	0.6	2.2	0.0	-0.8	-0.9	-0.4	-0.3	-0.6	-0.4	-0.4	-0.5	-1.5	-0.7	-1.3	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.0	-1.4	-0.6	-0.0	-1.2	-0.8	-0.5	-0.7	-1.3	0.2	0.3	-0.3	-0.1	-0.7
Illnesses of siblings: Diabetes	0.5	0.6	1.3	0.9	0.3	0.5	0.7	0.3	0.9	1.1	0.7	1.1	0.3	1.1	0.8	0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.6	-1.1	-0.7	-0.6	-1.2	-0.8	-1.1	-1.3	-1.1	-1.0	-0.2	-1.0	-0.1	-0.8
Leg fat mass (left)	0.5	2.1	4.8	-0.6	-2.1	-1.9	-1.1	-0.3	-1.1	-0.9	-1.3	-1.1	-2.2	-1.4	-2.0	-1.3
Irritable Bowel Disease (IBD)	0.4	0.9	3.7	0.4	-0.4	-1.0	-0.1	0.6	-0.9	-0.9	-0.2	-1.1	-1.4	-1.3	-1.9	-0.5
Coronary Artery Disease (CAD)	0.4	0.4	1.6	-0.6	0.5	0.8	-0.3	0.2	0.5	0.3	-0.5	0.9	1.3	0.7	0.9	-0.1
Neuroticism	0.4	1.0	2.3	-0.3	-1.5	-1.2	-0.2	0.1	-1.0	-1.0	-0.3	-1.3	-1.4	-1.2	-1.4	-0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.4	0.8	1.0	0.8	1.2	1.1	0.2	0.1	1.0	0.3	-0.1	0.1	0.3	0.5
Average weekly fortified wine intake	0.4	0.5	1.4	-0.7	0.2	-0.2	-0.7	-0.6	-0.8	-1.2	-0.7	-0.6	0.0	-0.9	0.9	-0.5
Qualifications: CSEs or equivalent	0.4	0.6	1.7	1.3	-0.6	0.3	0.8	1.2	0.5	0.7	0.6	0.7	-0.5	0.3	-1.1	0.3
Sitting height	0.4	2.6	15.8	0.1	3.0	1.5	0.5	-0.1	0.2	-0.3	0.8	0.3	2.1	0.7	4.0	1.0
Qualifications: None of the above	0.4	0.9	5.6	1.0	-0.7	0.2	0.9	0.7	0.8	1.1	0.5	0.8	-0.7	0.4	-2.4	0.1
Arm fat percentage (right)	0.4	1.6	5.2	-0.3	-2.2	-1.8	-0.7	0.0	-0.7	-0.4	-0.9	-0.6	-2.3	-0.9	-1.7	-1.2
Hip circumference	0.4	1.6	3.2	-0.8	-1.8	-1.6	-1.0	-0.6	-1.0	-1.0	-1.2	-1.2	-1.7	-1.5	-1.6	-0.9
Lung cancer (father)	0.4	0.4	1.0	0.4	0.0	0.6	0.4	0.3	0.8	0.9	0.2	1.0	0.6	0.9	1.0	0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.3	-0.1	1.0	1.2	0.1	0.4	0.6	0.3	0.1	0.5	1.5	0.3	1.2	1.4
Medication: Allopurinol	0.4	0.6	3.9	-0.5	1.1	0.5	-0.2	0.0	-0.0	-0.3	-0.0	-0.1	1.2	0.3	2.0	0.2
Medication: Seretide 50 evohaler	0.4	0.5	0.9	-0.3	-0.1	-0.7	-0.8	-0.8	-0.8	-0.9	-0.9	-0.9	-0.4	-0.9	0.3	-0.4
Had major operations	0.4	0.5	2.2	0.5	-0.5	-1.1	0.2	0.3	-0.7	-0.4	0.3	-0.8	-1.5	-0.4	-0.0	-0.9
Arm fat percentage (left)	0.4	1.8	5.9	-0.3	-2.2	-1.9	-0.7	-0.0	-0.8	-0.4	-1.0	-0.6	-2.4	-0.9	-1.9	-1.3
Medication for cholesterol	0.4	0.6	2.3	0.6	1.1	0.5	0.3	0.6	0.2	0.0	0.8	-0.4	0.9	0.2	1.5	0.9
Back pain experienced in last month	0.4	0.6	2.1	-1.1	-1.0	-0.2	-1.2	-0.7	-0.3	-0.4	-1.4	0.4	0.0	-0.3	-0.7	-0.7
Breast cancer (self-reported)	0.4	0.5	3.5	-0.3	0.1	0.2	-0.2	0.0	0.3	0.4	-0.2	0.8	1.0	1.1	1.9	-0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.7	0.3	-1.0	-1.1	-0.3	-0.4	-0.4	-0.1	-0.4	-0.8	-1.3	-0.6	-1.2	-0.4
Miserableness	0.4	0.6	1.3	-0.3	-1.1	-0.9	-0.4	-0.2	-0.9	-0.9	-0.4	-0.9	-1.1	-0.9	-0.7	-0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.7	0.1	0.3	0.5	0.3	0.7	0.3	0.5	0.2	1.2	0.7	1.3	0.8	-0.8
Alzheimer’s Disease (in mother)	0.3	0.4	0.9	0.8	0.4	0.4	0.9	0.8	0.6	0.6	0.7	0.9	-0.4	0.4	-0.4	0.1
Ulcerative Colitis (UC)	0.3	0.6	2.3	0.4	-0.4	-0.7	0.3	0.6	-0.7	-0.5	0.2	-0.8	-1.5	-1.1	-1.4	-0.4
HDL Cholesterol	0.3	0.5	2.7	0.1	-1.2	-0.7	-0.2	-0.1	-0.2	-0.1	-0.3	-0.3	-1.1	-0.7	-1.6	-0.1
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.1	0.1	0.8	0.5	0.6	0.9	0.6	0.3	0.3	0.3	0.4	0.1	0.0	1.1
Ulcerative Colitis	0.3	0.4	1.0	0.8	0.3	0.2	1.0	1.0	0.2	0.2	0.9	-0.3	-0.4	-0.3	-0.7	0.8
Systolic Blood Pressure	0.3	1.3	3.6	0.0	0.5	1.2	0.0	-0.1	1.5	1.5	-0.2	1.9	1.3	1.1	-1.6	0.9
Average weekly spirits intake	0.3	0.4	1.6	0.1	-0.8	-0.2	0.3	-0.6	-0.5	-0.4	0.1	-0.1	-1.0	-0.5	-1.2	-0.8
Ever had hysterectomy (womb removed)	0.3	0.4	1.0	-1.0	0.6	0.2	-0.5	-1.0	-0.1	-0.3	-0.6	-0.1	0.8	-0.1	1.0	0.1
Severe depression (siblings)	0.3	0.3	1.1	0.8	-0.4	-0.0	1.0	0.5	-0.1	0.1	0.8	0.2	-1.0	-0.1	-0.1	-0.2
Pack years adult smoking proportion	0.3	0.4	1.1	0.3	-0.6	0.2	0.2	0.3	1.0	1.1	-0.1	0.9	0.4	0.7	-1.0	0.6
Leg fat-free mass (left)	0.3	1.4	4.5	-0.8	-0.2	-1.2	-1.1	-0.7	-1.4	-1.7	-0.8	-2.1	-0.8	-1.8	0.3	-0.2
Stomach or abdominal pain in last month	0.3	0.3	1.2	-0.4	-0.6	-0.0	-0.9	-0.3	0.3	0.3	-1.0	0.7	0.3	0.2	-1.1	-0.0
Medication: Levothyroxine sodium	0.3	0.4	1.2	0.8	0.1	-0.3	1.1	0.5	0.6	1.0	1.1	0.2	-0.4	0.6	-0.3	0.6
Leg predicted mass (left)	0.3	1.3	4.3	-0.8	-0.1	-1.1	-1.1	-0.8	-1.4	-1.7	-0.8	-2.1	-0.7	-1.8	0.4	-0.2
Heart attack	0.3	0.4	1.4	-0.2	0.1	0.4	0.0	0.4	0.1	0.3	-0.0	1.0	0.6	1.2	0.9	-1.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.2	0.1	0.1	-0.5	0.1	-0.1	-0.7	-0.6	0.1	-0.7	-1.1	-0.9	-1.0	-0.7
Medication: Ramipril	0.3	0.4	1.4	-0.3	0.3	1.0	0.3	0.1	0.6	0.4	0.2	0.9	1.2	0.8	0.7	0.4
Medication: Simvastatin	0.3	0.4	1.5	-0.6	-0.7	-0.7	-0.6	-0.3	-0.5	-0.4	-0.8	0.3	-0.7	-0.0	-0.6	-1.2
Weight	0.3	1.6	3.0	-0.8	-1.0	-1.5	-1.1	-0.8	-1.4	-1.5	-1.1	-1.7	-1.5	-1.7	-0.5	-0.9
Worrier / anxious feelings	0.3	0.5	1.4	-0.1	-1.1	-0.7	-0.1	0.4	-0.7	-0.7	-0.1	-1.2	-0.9	-1.0	-0.8	-0.2
Number of live births	0.3	0.4	1.5	1.2	0.3	0.4	1.0	1.0	0.4	0.6	1.0	-0.0	0.0	0.3	0.1	0.7
Standing height	0.3	3.3	18.9	0.0	3.3	1.0	0.4	-0.8	-1.1	-1.8	0.9	-1.6	1.4	-0.9	4.3	0.8
Tense / ‘highly strung’	0.3	0.6	2.0	-0.9	-1.4	-0.6	-0.6	-0.3	-0.5	-0.4	-0.7	-0.1	-0.5	-0.2	-1.2	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.0	0.9	0.1	0.6	0.6	1.0	0.8	0.9	0.7	0.9	0.4	0.8	-0.6	0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.0	-0.1	-1.4	-0.6	-0.3	-0.3	-0.3	-0.2	-0.6	0.4	-1.1	-0.4	-0.8	-0.6
Glaucoma (self-reported)	0.3	0.3	1.3	-1.1	-0.1	-0.2	-0.6	-1.1	-0.4	-0.5	-0.7	-0.1	0.0	-0.3	0.5	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	3.8	0.1	-1.0	-1.1	-0.0	-0.3	-0.2	0.2	-0.2	-0.4	-1.1	-0.3	-2.0	-0.2
Comparative height size at age 10	0.3	1.9	10.2	0.2	2.8	1.2	0.4	-0.3	-0.1	-0.7	0.6	-0.2	1.8	-0.0	3.2	1.0
Chest pain or discomfort	0.3	0.4	1.0	-0.6	-1.0	-0.2	-0.8	-0.6	-0.6	-0.6	-0.8	-0.4	-0.1	-0.6	-0.9	-0.6
Supplements: Vitamin C	0.3	0.3	0.9	0.9	0.4	0.3	0.5	1.0	0.6	0.6	0.5	0.6	-0.0	0.5	0.3	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.8	-0.9	-0.2	0.0	-0.7	-0.7	-0.2	-0.2	-0.9	0.5	0.5	0.4	0.3	-0.7
Medication: Paracetamol	0.3	0.5	1.1	-0.4	-0.1	-1.1	-0.8	-0.5	-0.9	-0.8	-0.6	-1.0	-0.7	-0.6	0.2	-0.8
Heart disease (siblings)	0.3	0.4	1.3	-0.6	-0.6	-0.3	-0.9	-0.6	-0.5	-0.7	-1.1	0.0	-0.0	-0.5	-0.7	-0.8
Pack years of smoking	0.3	0.5	1.2	0.5	-0.4	0.3	0.3	0.4	1.0	1.1	-0.0	1.0	0.5	0.7	-0.9	0.6
Arm predicted mass (left)	0.3	1.4	3.5	-1.2	-0.3	-1.0	-1.4	-1.0	-1.3	-1.7	-1.2	-1.9	-0.3	-1.7	0.3	-0.3
Schizophrenia vs Biploar Disorder	0.2	0.3	1.3	-0.9	1.2	0.7	-0.0	-0.2	-0.0	-0.2	-0.3	0.6	0.7	0.2	0.7	-0.1
Mean Putamen Volume	0.2	0.2	0.5	-0.4	-0.5	-0.6	-0.5	-0.7	-0.2	-0.2	-0.3	-0.4	0.0	-0.0	0.7	-0.2
HbA1C	0.2	0.2	0.9	0.7	0.0	0.3	0.4	1.0	0.5	0.5	0.2	0.6	0.2	0.4	-0.5	0.5
Height	0.2	4.1	25.3	-0.6	3.1	0.7	-0.4	-1.5	-1.6	-2.5	0.2	-1.8	1.3	-1.3	5.0	0.1
Waist Hip Ratio (WHR)	0.2	0.7	2.2	0.1	1.2	1.1	0.3	0.2	0.6	0.4	0.4	0.8	1.5	0.9	1.3	0.6
Lung FEV1/FVC ratio	0.2	0.8	3.7	-0.5	-1.9	-0.9	-0.7	-0.9	-0.2	0.2	-1.1	0.5	-1.0	0.1	-1.0	-1.2
Systolic blood pressure, automated reading	0.2	0.6	4.6	-0.3	-0.8	-0.4	-0.7	-0.3	-0.1	0.0	-0.8	0.2	-0.7	-0.4	-2.1	-0.5
Vitamin and mineral supplements	0.2	0.2	1.1	-0.5	0.3	0.5	-0.5	-0.3	0.4	0.4	-0.3	0.3	1.0	0.4	0.2	0.4
Maternal smoking around birth	0.2	0.2	0.5	-0.7	-0.5	-0.6	-0.3	-0.6	-0.5	-0.5	-0.2	-0.5	-0.5	-0.3	0.3	-0.6
Age when periods started (menarche)	0.2	0.5	1.8	-0.8	0.1	0.4	-0.2	-0.4	0.5	0.7	-0.3	1.0	1.1	1.4	1.0	-0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.1	-0.2	0.5	0.3	-0.4	-0.1	0.0	0.0	-0.1	0.1	1.0	0.6	0.9	-0.1
Waist circumference	0.2	0.8	1.5	-0.5	-1.2	-1.2	-0.8	-0.4	-0.8	-0.7	-0.8	-0.9	-1.2	-1.0	-0.8	-0.6
Alcohol usually taken with meals	0.2	0.4	1.7	-0.7	0.2	-0.5	-0.6	-0.4	-0.5	-0.8	-0.1	-1.3	0.3	-0.6	0.9	0.2
Diabetes (self-reported)	0.2	0.4	0.9	0.5	-0.1	-0.0	1.0	0.8	0.6	0.7	0.8	0.4	-0.6	0.2	-0.7	0.5
Illnesses of siblings	0.2	0.3	0.9	-0.9	-0.1	-0.2	-0.5	-0.7	-0.4	-0.5	-0.6	-0.3	-0.2	-0.5	-1.0	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.9	-0.2	0.1	-0.3	-0.7	-0.2	-0.6	-0.7	-0.4	-0.3	-0.2	-0.2	0.9	-0.6
Prospective memory result	0.2	0.3	0.7	0.4	-0.3	0.4	0.4	0.2	0.7	0.9	0.5	0.4	0.3	0.4	-0.5	0.8
Birth weight of first child	0.2	0.4	1.2	0.5	0.9	0.6	1.1	0.9	0.1	0.1	0.9	-0.2	0.3	0.1	-0.1	0.5
Blood clot in the leg (DVT)	0.2	0.3	1.7	-0.2	1.3	0.9	0.3	-0.2	-0.2	-0.4	0.4	-0.3	0.8	-0.3	-0.0	0.4
Medication: Paracetamol	0.2	0.3	1.0	-0.4	-0.1	-0.6	-1.0	-0.5	-0.7	-0.6	-0.9	-0.5	-0.1	-0.2	0.4	-0.7
Arm fat-free mass (right)	0.2	0.9	3.1	-0.8	0.1	-0.7	-1.0	-0.7	-1.1	-1.4	-0.7	-1.8	-0.1	-1.5	0.4	0.2
Exposure to tobacco smoke outside home	0.2	0.2	0.7	-0.5	-0.2	-0.0	-0.2	0.1	-0.6	-0.8	-0.2	-0.3	-0.7	-0.8	-0.3	-0.5
Number of full brothers	0.2	0.3	1.5	0.0	-0.8	-0.1	0.0	-0.1	0.0	-0.2	-0.2	-0.5	-0.6	-1.0	-1.2	0.4
Number of children fathered	0.2	0.2	0.6	0.2	0.1	0.4	0.4	0.7	0.5	0.4	0.2	0.5	-0.0	-0.0	-0.7	0.6
Medication: Ibuprofen	0.2	0.2	1.8	0.6	0.7	0.0	0.0	0.4	-0.1	-0.1	0.3	-0.1	-0.1	0.2	1.4	-0.1
Medication: Omeprazole	0.2	0.3	1.3	-0.5	-0.3	-0.2	-0.7	-1.1	-0.3	-0.2	-0.8	0.2	0.2	0.2	-0.1	-0.8
Pulse rate, automated reading	0.2	0.6	1.8	0.9	-1.3	-1.2	0.2	0.5	0.1	0.6	0.1	-0.3	-1.2	0.1	-1.3	-0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	-0.4	0.0	-0.1	-0.5	-0.5	-0.5	-0.6	-0.6	-0.2	0.0	-0.5	-0.5	-0.4
Medication: Aspirin	0.2	0.3	0.9	-0.9	-0.5	-0.2	-0.6	-0.6	-0.2	-0.2	-0.8	0.4	0.1	0.1	-0.2	-0.9
Knee pain experienced in last month	0.2	0.4	1.3	-1.1	-0.6	-0.1	-1.0	-0.6	-0.1	-0.1	-0.9	0.1	0.6	0.2	0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.6	0.0	0.7	0.0	0.2	-0.5	-0.4	-0.7	0.5	-1.0	0.2	-0.4	1.6	0.2
Leg fat-free mass (right)	0.2	1.1	4.1	-0.6	-0.0	-1.0	-0.9	-0.6	-1.2	-1.5	-0.6	-2.0	-0.5	-1.7	0.5	0.1
Eye problems/disorders: Cataract	0.2	0.2	0.6	-0.7	-0.5	-0.4	-0.4	-0.2	-0.4	-0.5	-0.5	-0.1	-0.4	-0.2	0.4	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.8	-0.3	0.2	-0.1	-0.9	-0.6	-0.5	-0.7	-0.5	-0.5	0.4	-0.2	0.4	-0.5
Osteoporosis (self-reported)	0.2	0.2	1.0	0.5	1.0	0.1	0.3	-0.1	0.1	0.2	0.7	-0.5	0.5	0.1	-0.1	0.6
Medication: Aspirin	0.2	0.3	0.7	-0.9	-0.5	-0.1	-0.6	-0.5	-0.1	-0.1	-0.8	0.4	0.2	0.1	-0.7	-0.7
Whole body water mass	0.2	1.0	3.3	-0.7	0.5	-0.6	-0.9	-0.6	-1.1	-1.5	-0.6	-1.8	0.1	-1.5	1.1	0.2
Leg predicted mass (right)	0.2	1.0	3.8	-0.6	0.1	-0.9	-0.8	-0.5	-1.1	-1.4	-0.5	-2.0	-0.5	-1.6	0.6	0.2
Alcohol drinker status: Never	0.2	0.3	0.7	0.7	-0.1	0.1	0.2	0.6	0.7	0.9	0.2	0.3	0.4	0.5	-0.1	0.8
Basal metabolic rate	0.2	1.0	3.3	-0.7	0.1	-0.8	-1.0	-0.6	-1.2	-1.5	-0.7	-1.8	-0.3	-1.6	0.7	-0.0
Arm fat-free mass (left)	0.2	0.9	3.2	-0.8	0.1	-0.8	-1.0	-0.7	-1.1	-1.5	-0.7	-1.8	-0.2	-1.5	0.5	0.0
Fractured/broken bones in last 5 years	0.2	0.2	1.4	0.2	0.7	-0.1	-0.0	-0.3	-0.3	-0.3	0.2	-0.4	0.0	0.0	1.2	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.1	-0.3	1.1	0.6	0.1	-0.4	-0.4	-0.7	0.2	-0.5	0.5	-0.6	-0.3	0.1
Crohns Disease (2017)	0.1	0.3	2.4	0.3	0.3	-0.2	-0.0	0.5	-0.5	-0.5	-0.0	-0.5	-0.3	-0.6	-1.6	-0.1
Blood Eosinophil Count	0.1	1.1	5.5	-0.5	1.7	0.3	0.2	0.1	-1.0	-1.5	0.6	-1.2	0.4	-0.7	2.4	-0.0
Heel T-Score	0.1	1.0	4.5	-1.4	-0.3	0.1	-1.5	-2.1	-0.2	-0.5	-1.6	0.7	0.6	-0.0	-0.6	-0.8
BMI	0.1	0.3	1.4	-0.0	-1.2	-0.7	-0.3	0.7	0.3	0.5	-0.2	-0.1	-0.6	-0.0	-0.8	0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.3	-0.3	-0.3	-0.1	0.1	-0.3	0.4	0.4	-0.1	0.6	-0.1	0.3	-0.5	-0.1
Tanning	0.1	1.0	1.8	-1.2	-0.7	-0.8	-1.2	-1.2	-1.1	-1.3	-1.2	-0.9	-0.6	-1.2	-0.2	-0.9
Medication: Metformin	0.1	0.2	0.5	0.6	0.0	-0.2	0.6	0.6	0.2	0.2	0.7	-0.2	-0.3	-0.1	0.4	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.9	-0.9	-0.4	0.2	-0.4	-0.9	0.1	-0.0	-0.6	0.8	0.2	0.4	0.2	-0.7
Serious illness, injury or assault to yourself	0.1	0.1	0.8	-0.3	-0.0	-0.0	-0.1	-0.3	-0.2	-0.2	0.1	0.1	0.1	0.2	0.9	-0.5
Supplements: Glucosamine	0.1	0.1	0.3	-0.1	0.1	0.3	-0.0	-0.0	-0.4	-0.5	-0.0	-0.0	0.1	-0.1	0.6	-0.4
Impedance of leg (left)	0.1	0.5	1.4	0.4	0.3	0.9	0.7	-0.1	0.5	0.6	0.6	1.2	0.5	1.1	0.7	-0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.4	-0.4	-0.1	-0.1	-0.4	0.1	0.3	0.3	-0.4	0.5	0.5	0.6	0.5	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.9	-0.8	-0.2	0.4	-0.1	-0.8	0.4	0.4	-0.4	0.9	0.4	0.6	0.1	-0.3
Impedance of arm (right)	0.1	0.5	3.8	0.3	0.8	0.5	0.6	-0.3	-0.1	-0.1	0.5	0.5	0.2	0.7	2.0	-0.5
Trunk fat-free mass	0.1	0.8	2.6	-0.6	1.1	-0.0	-0.6	-0.3	-0.7	-1.2	-0.3	-1.3	0.7	-1.0	1.6	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.3	0.6	-0.2	0.2	0.6	0.2	0.4	0.3	0.5	0.3	0.2	0.4	0.1	0.3
Pulse rate	0.1	0.2	0.6	0.3	-0.8	-0.7	-0.1	-0.1	0.2	0.4	-0.2	0.1	-0.5	0.4	0.3	-0.3
Happiness	0.1	0.1	0.4	0.5	0.7	0.1	0.7	0.4	-0.1	-0.1	0.4	0.1	-0.3	0.1	-0.2	-0.2
Medication: Cholesterol lowering	0.1	0.2	0.6	0.4	-0.4	-0.6	0.3	0.2	0.0	0.3	0.3	0.1	-0.8	0.3	-0.3	-0.8
Impedance of arm (left)	0.1	0.4	3.0	0.5	0.8	0.5	0.7	-0.3	-0.1	-0.1	0.6	0.4	-0.1	0.5	1.7	-0.4
Trunk predicted mass	0.1	0.9	2.6	-0.7	1.1	-0.1	-0.7	-0.4	-0.8	-1.3	-0.4	-1.4	0.7	-1.0	1.6	0.5
Exposure to tobacco smoke at home	0.1	0.2	0.6	-0.7	-0.4	0.1	-0.4	-0.8	-0.1	-0.2	-0.5	0.4	0.3	0.1	0.2	-0.3
Loud music exposure frequency	0.1	0.1	0.7	-0.8	0.1	0.0	-0.4	-0.3	-0.2	-0.4	-0.4	-0.2	0.3	-0.3	-0.4	-0.1
Medication: Amlodipine	0.1	0.2	0.8	0.4	-0.4	-0.2	0.1	0.0	0.5	0.7	-0.0	0.6	-0.1	0.5	-0.9	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.8	0.2	-0.1	0.3	0.3	0.6	0.2	-0.0	0.4	-0.0	0.2	-0.1	0.9	0.6
Arm predicted mass (right)	0.1	0.8	2.8	-0.7	0.2	-0.6	-0.9	-0.5	-1.0	-1.3	-0.6	-1.7	-0.0	-1.4	0.5	0.2
Family relationship satisfaction	0.1	0.1	0.6	0.2	0.3	0.3	0.3	0.2	0.1	0.0	0.3	0.2	0.3	0.4	0.8	-0.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	1.0	-0.1	1.0	0.4	0.3	-0.0	-0.1	-0.1	0.4	-0.5	0.3	-0.2	-0.1	0.3
Whole body fat-free mass	0.1	0.8	2.8	-0.6	0.7	-0.4	-0.7	-0.4	-0.9	-1.3	-0.4	-1.7	0.2	-1.3	1.1	0.4
Diabetes diagnosed by doctor	0.1	0.2	0.9	-0.1	-0.4	-0.4	0.5	0.2	0.0	0.1	0.4	-0.1	-1.0	-0.4	-0.7	0.0
Ever taken oral contraceptive pill	0.1	0.1	0.5	0.3	0.2	-0.1	0.6	0.1	-0.1	0.0	0.7	-0.4	-0.3	-0.0	0.2	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.7	-0.1	-0.2	-0.3	0.0	-0.4	-0.1	-0.1	-0.1	-0.1	-0.6	-0.4	-0.9	-0.0
Medication: Lisinopril	0.1	0.1	0.6	0.4	0.2	-0.4	-0.2	0.0	-0.2	-0.1	0.1	-0.3	0.0	0.2	0.8	-0.2
Number of operations (self-reported)	0.1	0.2	1.2	-0.2	0.2	0.0	-0.0	0.1	0.2	0.3	0.1	0.3	0.4	0.7	1.1	-0.1
Irritability	0.1	0.1	0.6	-0.2	-0.4	-0.1	0.0	-0.1	-0.1	-0.0	-0.2	0.2	-0.2	0.1	-0.8	-0.5
Diastolic blood pressure, automated reading	0.1	0.4	2.4	-0.1	-0.9	-0.4	-0.9	-0.1	0.2	0.3	-1.1	0.3	-0.2	-0.1	-1.6	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.4	-0.2	-0.0	0.1	-0.4	-0.4	0.3	0.4	-0.4	0.6	0.7	0.7	0.1	-0.1
Impedance of whole body	0.1	0.5	2.4	0.4	0.6	0.7	0.7	-0.4	0.2	0.2	0.7	0.8	0.3	0.8	1.6	-0.3
Ovarian Cancer	0.0	0.0	0.2	0.1	0.0	0.2	-0.1	0.1	0.0	0.0	0.0	0.2	0.2	0.2	0.5	-0.1
Diabetes (father)	0.0	0.1	0.5	-0.7	-0.0	0.1	-0.2	0.3	-0.1	-0.2	-0.2	0.1	0.0	-0.2	-0.0	0.0
Impedance of leg (right)	0.0	0.2	0.7	0.1	0.3	0.7	0.3	-0.4	0.1	0.1	0.2	0.9	0.2	0.7	0.4	-0.6
Multivitamins +/- minerals	0.0	0.0	0.1	0.1	-0.1	-0.0	0.4	0.1	-0.1	-0.1	0.2	-0.1	-0.3	-0.2	0.2	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.2	-0.1	-0.4	0.1	0.1	-0.1	-0.1	0.1	0.0	0.1	-0.0	0.1	-0.1	-0.3
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.2	-0.4	-0.2	-0.1	-0.2	-0.2	-0.1	-0.1	-0.3	-0.1	0.1	-0.3	-0.4	-0.1
Leg pain on walking	0.0	0.1	0.2	0.4	-0.4	-0.2	-0.3	0.1	-0.1	-0.1	-0.4	0.2	-0.1	0.0	-0.2	-0.4
Illnesses of father: High blood pressure	0.0	0.1	0.2	-0.2	-0.0	0.3	0.4	0.2	0.3	0.3	0.3	0.3	-0.0	0.1	-0.2	0.1

Hub : Genes

C2orf42

Models

Trait associations