Best TWAS P=2.45e-08 · Best GWAS P=3.52e-09 conditioned to 0.0495
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RAD18 | 0.24 | 0.12 | lasso | 3 | 0.10 | 2.7e-08 | -5.5 | 5.4 | 7.0e-08 | -0.82 | 0.06 | 0.94 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RAD18 | 0.08 | 0.04 | bslmm | 804 | 0.06 | 5.9e-08 | -5.7 | 5.3 | 1.0e-07 | -0.39 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | LMCD1 | 0.17 | 0.10 | enet | 4 | 0.13 | 2.0e-04 | -5.4 | 5.5 | 2.9e-08 | -0.03 | 0.02 | 0.84 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | RAD18 | 0.11 | 0.07 | lasso | 3 | 0.07 | 1.7e-07 | -5.6 | 5.6 | 2.5e-08 | -0.83 | 0.02 | 0.98 | TRUE |