Best TWAS P=5.6e-11 · Best GWAS P=8.84e-23 conditioned to 3.13e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SUSD5 | 0.20 | 0.26 | lasso | 1 | 0.25 | 5.5e-19 | 6.2 | 6.2 | 6.6e-10 | -0.11 | 1.00 | 0 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SUSD5 | 0.27 | 0.11 | lasso | 5 | 0.15 | 2.4e-19 | 6.0 | 6.6 | 5.6e-11 | -0.09 | 1.00 | 0 | TRUE |
| 3 | YFS | Blood | GLB1 | 0.05 | 0.01 | enet | 9 | 0.02 | 5.2e-06 | 3.4 | 5.1 | 2.9e-07 | -0.07 | 0.85 | 0 | TRUE |