TWAS hub - MYO1F

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Brain Lower Grade Glioma	0.0502	0.0246	0.00056	0.014	0.030	0.024	NA	0.021	0.0085	0.00022	0.00082	NA	0.0016
2	TCGA	Lung Squamous Cell Carcinoma	0.0362	0.0191	0.00470	0.002	0.022	0.014	NA	0.016	0.2000	0.00140	0.00880	NA	0.0054

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
HDL Cholesterol	14.8	24.7	29.2	5.4	4.5
Mouth/teeth dental problems: Loose teeth	10.5	12.5	14.5	3.2	3.8
Trunk predicted mass	9.0	51.5	77.4	-8.8	-5.1
Trunk fat-free mass	8.9	51.3	77.1	-8.8	-5.1
Standing height	8.3	82.5	121.0	-11.0	-6.6
Comparative height size at age 10	8.2	44.9	61.4	-7.8	-5.3
Mouth/teeth dental problems	7.9	12.1	13.6	-3.7	-3.3
Arm predicted mass (left)	7.5	38.0	59.8	-7.7	-4.0
Whole body water mass	7.4	42.4	65.0	-8.1	-4.5
Whole body fat-free mass	7.2	41.1	63.2	-8.0	-4.4
Sitting height	7.0	49.7	74.3	-8.6	-5.0
Forced expiratory volume in 1-second (FEV1), predicted	7.0	14.4	20.1	-4.5	-3.0
Arm predicted mass (right)	6.9	35.2	56.3	-7.5	-3.8
Arm fat-free mass (left)	6.9	35.2	55.2	-7.4	-3.9
Arm fat-free mass (right)	6.7	34.2	54.2	-7.4	-3.8
Height	6.6	126.9	196.0	-14.0	-7.6
Basal metabolic rate	6.6	36.4	56.8	-7.5	-4.0
Basal cell carcinoma (self-reported)	6.5	7.7	8.0	-2.8	-2.7
Pulse rate	5.9	10.0	12.8	2.7	3.6
Triglycerides	5.8	9.4	11.8	-2.6	-3.4
Coronary Artery Disease (CAD)	5.6	6.7	8.6	-2.9	-2.2
Forced vital capacity (FVC), Best measure	5.5	20.0	35.3	-5.9	-2.2
Forced vital capacity (FVC)	5.2	20.0	34.9	-5.9	-2.2
Mouth/teeth dental problems: Dentures	5.1	8.7	12.6	3.6	2.2
Cholesterol lowering medication	5.1	7.5	7.8	-2.7	-2.8
Hand grip strength (right)	4.8	13.0	16.6	-4.1	-3.1
Diabetes (father)	4.6	5.7	6.1	2.3	2.5
Leg fat-free mass (left)	4.6	24.3	38.9	-6.2	-3.1
Hand grip strength (left)	4.5	11.9	15.3	-3.9	-2.9
Leg predicted mass (left)	4.5	23.8	38.3	-6.2	-3.1
Leg fat-free mass (right)	4.5	23.8	37.9	-6.2	-3.1
Leg predicted mass (right)	4.4	23.7	37.6	-6.1	-3.1
Medication: Lansoprazole	4.3	4.9	6.0	-2.4	-2.0
Weight	4.1	20.3	31.8	-5.6	-3.0
Tinnitus: Yes, now most or all of the time	4.0	4.6	5.7	-1.9	-2.4
Forced expiratory volume in 1-second (FEV1), Best measure	3.7	11.8	19.9	-4.5	-2.0
Waist Hip Ratio (WHR)	3.6	16.3	21.9	-4.7	-3.3
Cardiovascular Disease	3.5	11.6	16.6	-4.1	-2.6
Serious illness, injury or assault of a close relative in last 2 years	3.5	4.0	5.6	2.4	1.6
Medication: Metformin	3.4	4.8	7.7	-2.8	-1.4
Father’s age at death	3.4	4.6	6.6	2.6	1.6
Chronic bronchitis/emphysema (mother)	3.4	3.9	5.2	1.6	2.3
Forced expiratory volume in 1-second (FEV1)	3.3	11.0	18.0	-4.2	-2.0
Medication: Blood pressure	3.2	5.7	8.0	-2.8	-1.9
Waist circumference	2.9	10.5	17.4	-4.2	-1.9
Medication: Atorvastatin	2.8	3.4	3.9	-1.7	-2.0
High blood pressure (mother)	2.7	3.8	5.9	-2.4	-1.3
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.3	6.6	1.4	2.6
Unable to work because of sickness or disability	2.7	3.6	4.4	1.7	2.1
Pain experienced in last month	2.7	4.5	7.7	-1.1	-2.8
Pulse rate, automated reading	2.6	8.5	11.3	2.4	3.4
Blood Eosinophil Count	2.5	18.9	21.3	-4.6	-4.1
Crohns Disease (2017)	2.4	5.2	6.2	2.5	2.1
Hypothyroidism (self reported)	2.4	5.5	5.6	2.3	2.4
Diabetes (self-reported)	2.4	3.7	6.4	-2.5	-1.0
Headache pain in last month	2.4	4.1	6.6	1.2	2.6
Medication for cholesterol, blood pressure or diabetes	2.4	4.1	6.8	2.6	1.1
Leg pain on walking	2.4	3.0	4.8	1.2	2.2
Mouth/teeth dental problems: Mouth ulcers	2.4	3.8	5.0	1.6	2.2
Supplements: Zinc	2.2	2.4	2.7	-1.6	-1.4
Fed-up feelings	2.2	4.0	5.0	1.7	2.2
Rheumatoid Arthritis	2.1	2.8	4.6	1.0	2.2
Type 2 Diabetes (T2D) (2018)	2.1	4.0	6.9	-2.6	-1.1
Lung FEV1/FVC ratio	2.1	10.5	20.0	4.5	1.1
Medication: Co-codamol	2.1	2.5	2.8	-1.7	-1.5
Maternal smoking around birth	2.1	3.0	5.9	0.5	2.4
Medication: Amlodipine	2.1	2.9	3.9	-2.0	-1.4
Neck or shoulder pain in last month	2.1	2.9	3.5	1.5	1.9
Stomach or abdominal pain in last month	2.0	2.4	4.7	0.4	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.3	4.5	-2.0	-2.1
Financial difficulties in last 2 years	1.9	2.6	4.8	0.6	2.2
Hip circumference	1.9	8.0	13.2	-3.6	-1.7
Depression (self-reported)	1.9	2.2	3.3	1.1	1.8
Medication for cholesterol	1.9	2.9	3.5	1.5	1.9
Medication: Aspirin	1.9	2.4	3.2	-1.8	-1.3
High blood pressure	1.8	5.0	7.0	-2.7	-1.7
Happiness	1.8	2.2	3.3	1.1	1.8
Alcohol intake frequency.	1.8	4.3	4.6	2.0	2.1
Back pain experienced in last month	1.8	2.6	5.1	0.3	2.2
Ovarian Cancer	1.7	2.2	3.2	-1.1	-1.8
Hearing difficulty/problems with background noise	1.7	2.7	3.3	-1.5	-1.8
Supplements: Vitamin C	1.7	2.1	3.5	-1.9	-0.8
Diabetes diagnosed by doctor	1.7	2.8	4.5	-2.1	-1.0
Risk taking	1.7	2.5	4.6	-2.1	-0.6
Vascular/heart problems diagnosed by doctor	1.7	4.6	7.8	2.8	1.2
Frequency of depressed mood in last 2 weeks	1.6	2.2	3.3	1.1	1.8
Financial situation satisfaction	1.6	2.0	3.5	-1.9	-0.7
Number of incorrect matches in round	1.5	2.5	5.0	-0.1	-2.2
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	2.7	1.0	1.6
Medication: Aspirin	1.5	2.0	2.6	-1.6	-1.2
Hypertension (Self-reported)	1.5	4.1	6.2	-2.5	-1.4
Hair/balding pattern: Pattern 2	1.4	1.8	2.0	1.4	1.3
Illnesses of mother	1.4	1.8	2.8	1.7	-0.9
Breastfed as a baby	1.4	1.8	3.4	1.8	0.4
Average weekly red wine intake	1.4	2.1	2.7	1.6	1.2
Fractured/broken bones in last 5 years	1.4	1.8	2.0	-1.4	-1.2
Lupus	1.3	2.0	2.9	1.1	1.7
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	4.1	-0.1	2.0
Pain type(s) experienced in last month: Hip pain	1.3	1.6	2.2	-1.5	-1.0
Alcohol drinker status: Previous	1.3	1.4	2.8	0.3	1.7
Body Mass Index (BMI) (2010)	1.2	1.7	2.2	1.5	1.1
Vitamin and mineral supplements	1.2	1.6	2.0	1.4	1.1
Medication: Simvastatin	1.2	1.7	1.8	-1.3	-1.3
Time employed in main current job	1.2	1.4	1.6	-1.3	-1.1
Age at last live birth	1.2	1.7	2.4	-1.0	-1.6
Osteoporosis (self-reported)	1.2	1.5	1.6	1.2	1.3
Crohns Disease (2012)	1.1	1.8	2.2	1.5	1.2
Fasting Glucose	1.1	1.4	1.5	-1.1	-1.2
Ulcerative Colitis	1.1	1.5	2.4	-1.5	-0.8
Arm fat mass (right)	1.1	4.7	8.8	-3.0	-0.7
Knee pain experienced in last month	1.1	1.7	2.5	1.6	1.0
Smoking status: Previous	1.1	1.7	2.6	-0.9	-1.6
Smoking status: Current	1.1	1.7	3.2	0.5	1.8
Pack years of smoking	1.1	1.6	3.1	-0.2	1.8
Age at First Birth	1.0	1.4	2.0	1.4	0.9
Pack years adult smoking proportion	1.0	1.6	2.9	-0.4	1.7
Trunk fat mass	1.0	4.5	8.5	-2.9	-0.7
Had other major operations	1.0	1.3	1.5	1.0	1.2
Illnesses of siblings	1.0	1.3	1.6	1.3	1.0
Impedance of arm (left)	1.0	4.7	7.0	2.6	1.6
Peak expiratory flow (PEF)	1.0	2.3	2.5	-1.6	-1.4
Emphysema/chronic bronchitis	1.0	1.1	1.5	0.9	1.2
Angina (self-reported)	1.0	1.4	2.5	-1.6	-0.5
Medication: Ibuprofen	1.0	1.2	1.5	0.9	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.4	-0.3	-1.5
Arm fat mass (left)	1.0	4.1	7.8	-2.8	-0.6
Schizophrenia vs Biploar Disorder	0.9	1.2	1.8	1.3	0.9
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.7	-0.6	1.3
Qualifications: CSEs or equivalent	0.9	1.2	1.5	-1.2	-0.9
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	1.8	-1.0	-1.3
Family relationship satisfaction	0.9	1.1	2.0	-1.4	-0.5
Loneliness, isolation	0.9	1.3	2.2	-1.5	-0.6
Supplements: Fish oil (including cod liver oil)	0.9	1.1	2.0	-0.5	-1.4
Illnesses of father: High blood pressure	0.9	1.1	1.6	0.8	1.3
Blood White Count	0.8	6.1	11.6	-3.4	-0.8
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	1.1	1.1	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.0	-1.4	0.3
Serious illness, injury or assault to yourself	0.8	0.9	1.2	-1.1	-0.8
Qualifications: None of the above	0.8	1.6	3.0	0.5	1.7
Neuroticism score	0.8	1.6	2.0	1.1	1.4
Hair/balding pattern: Pattern 3	0.8	1.2	1.5	-0.9	-1.2
Pulse wave reflection index	0.8	1.0	2.0	0.1	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	2.1	0.2	1.4
Health satisfaction	0.8	1.1	1.2	-1.0	-1.1
Medication for pain relief, constipation, heartburn	0.8	1.4	2.1	-0.8	-1.5
Whole body fat mass	0.8	3.4	6.6	-2.6	-0.4
Irritable Bowel Disease (IBD)	0.7	1.7	1.8	1.4	1.3
Heel T-Score	0.7	5.8	10.5	3.2	1.1
Sensitivity / hurt feelings	0.7	1.3	2.6	0.1	1.6
Angina	0.7	0.9	1.7	-1.3	-0.3
Townsend deprivation index at recruitment	0.7	1.0	1.7	-1.3	0.5
Current tobacco smoking	0.7	1.2	2.2	0.3	1.5
Impedance of arm (right)	0.7	3.4	5.2	2.3	1.3
Falls in the last year	0.7	0.9	1.7	-1.3	-0.3
Exposure to tobacco smoke outside home	0.7	0.9	1.6	-1.3	-0.4
Leg fat mass (right)	0.7	2.7	5.3	-2.3	-0.3
Overall health rating	0.7	1.4	2.8	0.3	1.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	0.9	-0.8	-0.9
Qualifications: nursing, teaching	0.7	1.1	1.7	0.7	-1.3
Average weekly champagne plus white wine intake	0.7	1.0	1.1	1.1	0.9
Miserableness	0.7	1.2	2.4	-0.2	1.6
High cholesterol (Self-reported)	0.7	1.2	1.2	-1.1	-1.1
Commuting to job workplace: Cycle	0.7	0.9	0.9	1.0	0.9
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.5	-1.2	-0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.4	-0.1	1.2
Medication: Paracetamol	0.6	0.9	1.6	0.5	1.3
Birth weight	0.6	1.2	2.0	-0.7	-1.4
Pulse wave peak to peak time	0.6	0.7	1.3	-1.2	-0.3
Eye problems/disorders: None of the above	0.6	0.7	0.9	-1.0	-0.7
Migraine (self-reported)	0.6	0.8	1.1	0.7	1.1
Suffer from ‘nerves’	0.6	1.0	1.2	0.9	1.1
Illnesses of father: Heart disease	0.6	0.9	1.5	-1.2	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	0.7	0.8	0.9
Alcohol drinker status: Never	0.6	0.8	1.4	0.3	1.2
Impedance of whole body	0.6	3.0	4.6	2.1	1.2
Leg fat mass (left)	0.6	2.4	4.7	-2.2	-0.2
Neuroticism (Nagel 2018)	0.5	1.1	2.0	0.4	1.4
Mean Putamen Volume	0.5	0.5	0.8	0.9	0.5
Lung FVC	0.5	2.5	5.0	-2.2	-0.3
Average weekly spirits intake	0.5	0.6	0.7	-0.7	-0.9
Past tobacco smoking	0.5	0.9	1.0	0.9	1.0
Alcohol usually taken with meals	0.5	0.7	1.5	1.2	0.1
Lung cancer (father)	0.5	0.6	1.0	0.3	1.0
Glaucoma (self-reported)	0.5	0.6	0.8	0.9	0.6
Comparative body size at age 10	0.5	1.5	1.6	1.3	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	0.8	-0.9	-0.6
Medication: Seretide 50 evohaler	0.5	0.6	1.1	-1.0	-0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.1	0.1	-1.1
Mood swings	0.5	0.9	1.8	0.1	1.4
Mineral and other dietary supplements	0.5	0.7	1.3	0.4	1.1
Mother’s age at death	0.5	0.6	0.7	0.6	-0.8
Medication: Blood pressure	0.5	1.0	1.4	-0.8	-1.2
Number of operations (self-reported)	0.5	0.8	1.2	-1.1	-0.6
Myopia	0.5	0.7	1.2	-1.1	-0.6
Depressed Affect (Nagel 2018)	0.4	0.9	1.5	0.6	1.2
Primary Biliary Cirrhosis	0.4	0.5	0.9	-1.0	-0.3
Blood Platelet Count	0.4	4.2	8.0	2.8	0.7
Neuroticism	0.4	1.0	1.1	1.0	1.0
Tanning	0.4	4.9	5.5	-2.3	-2.1
Medication: Atenolol	0.4	0.5	0.5	-0.7	-0.7
Impedance of leg (left)	0.4	1.9	3.0	1.7	0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.0	0.2	1.0
Heart attack	0.4	0.5	1.0	-1.0	-0.0
Medication: Ramipril	0.4	0.5	0.5	-0.7	-0.7
Fluid intelligence score	0.4	0.8	1.5	1.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	0.9	-0.9	0.5
Birth weight of first child	0.4	0.7	1.0	1.0	0.6
Worry too long after embarrassment	0.4	0.7	1.1	0.6	1.0
Number of children fathered	0.4	0.5	0.8	-0.3	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.0	1.0	-0.2
Long-standing illness, disability or infirmity	0.4	0.7	1.3	0.2	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.7	0.3	0.8
Medication: Gliclazide	0.4	0.5	0.9	0.3	0.9
Number of self-reported non-cancer illnesses	0.4	0.7	1.4	-1.2	0.3
Ever smoked	0.4	0.7	0.7	-0.8	-0.8
Breast Cancer	0.3	0.7	1.1	1.1	0.5
Blood Red Count	0.3	3.1	5.6	2.4	0.8
Hearing difficulty/problems: Yes	0.3	0.4	0.4	-0.6	-0.6
Severe depression (siblings)	0.3	0.3	0.4	-0.7	-0.5
Average weekly fortified wine intake	0.3	0.4	0.6	0.8	0.4
Multivitamins +/- minerals	0.3	0.3	0.5	-0.4	-0.7
Supplements: Glucosamine	0.3	0.4	0.7	0.8	0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.7	0.8	0.3
Worrier / anxious feelings	0.3	0.6	0.7	0.7	0.8
Medication: Cholesterol lowering	0.3	0.4	0.8	-0.9	0.1
Prospective memory result	0.3	0.4	0.6	0.4	0.8
Hair/balding pattern: Pattern 4	0.3	0.7	1.3	1.1	0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.9	0.2	0.9
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	0.7	0.8	0.8
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	0.3	1.0
Age at first live birth	0.3	0.6	1.1	0.2	-1.1
Heart disease (mother)	0.3	0.4	0.6	-0.8	0.4
Number of full sisters	0.3	0.3	0.7	0.8	0.0
Chest pain or discomfort	0.3	0.4	0.6	0.5	0.8
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.6	0.2	0.7
Hearing aid user	0.3	0.3	0.4	0.6	-0.5
Eye problems/disorders: Glaucoma	0.3	0.4	0.6	0.8	0.5
Medication: Paracetamol	0.3	0.5	0.7	0.6	0.8
Leg fat percentage (left)	0.3	1.0	2.0	0.3	1.4
Average weekly beer plus cider intake	0.3	0.4	0.7	-0.8	0.4
Ever depressed for a whole week	0.3	0.4	0.8	-0.9	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.2	1.1	-0.6
Worry (Nagel 2018)	0.2	0.4	0.5	0.6	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.4	0.5	0.6
Reaction Time	0.2	0.4	0.8	0.9	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.6	0.6	0.8	-0.7
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.4	-0.6	-0.4
Smoking Status	0.2	0.4	0.5	0.6	0.7
Number of treatments/medications taken	0.2	0.4	0.8	-0.9	-0.4
Relative age of first facial hair	0.2	0.4	0.9	0.9	0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.5	-0.7	-0.3
Impedance of leg (right)	0.2	0.9	1.5	1.2	0.6
Taking other prescription medications	0.2	0.4	0.4	-0.7	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.9	0.4	-0.9
Exposure to tobacco smoke at home	0.2	0.2	0.4	-0.1	0.6
Blood clot in the leg (DVT)	0.2	0.3	0.6	-0.7	-0.2
Gout (self-reported)	0.2	0.2	0.3	-0.4	0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.6	-0.0	-0.8
Body fat percentage	0.2	0.6	1.2	-0.0	1.1
Leg fat percentage (right)	0.2	0.6	1.2	-0.1	1.1
Qualifications: College or University degree	0.2	0.6	1.3	1.1	0.0
Medication: Allopurinol	0.2	0.3	0.6	0.1	0.8
Medication: Omeprazole	0.2	0.2	0.2	-0.5	0.4
Mean time to correctly identify matches	0.2	0.4	0.7	0.9	-0.4
Illnesses of siblings: Diabetes	0.2	0.2	0.3	-0.5	-0.4
Ever had bowel cancer screening	0.2	0.2	0.4	-0.1	-0.7
Friendships satisfaction	0.2	0.2	0.3	-0.6	0.3
Commuting to job workplace: Walk	0.2	0.3	0.3	-0.4	-0.6
Asthma (self-reported)	0.2	0.3	0.5	0.7	0.4
Guilty feelings	0.2	0.4	0.7	-0.2	0.8
Commuting to job workplace: Public transport	0.2	0.3	0.5	-0.7	-0.0
Medication: Bendroflumethiazide	0.2	0.3	0.3	-0.6	-0.5
Medication: Lisinopril	0.2	0.2	0.3	-0.6	-0.3
Irritability	0.2	0.4	0.6	0.5	0.8
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.4	-0.7	-0.4
Age started oral contraceptive pill	0.2	0.3	0.3	-0.5	-0.6
Diastolic blood pressure, automated reading	0.2	0.7	1.2	0.3	1.1
Supplements: Calcium	0.2	0.2	0.3	0.5	0.4
Heart disease (siblings)	0.2	0.2	0.3	0.4	0.5
Bipolar Disorder or Schizophrenia	0.1	0.1	0.3	-0.5	0.0
Depression (Nagel 2018)	0.1	0.2	0.4	-0.1	0.7
Schizophrenia (2018)	0.1	0.1	0.2	-0.5	0.0
Ulcerative Colitis (UC)	0.1	0.1	0.1	-0.3	-0.3
Prostate Cancer	0.1	0.1	0.2	0.1	0.4
HbA1C	0.1	0.1	0.2	-0.1	0.4
LDL Cholesterol	0.1	0.1	0.3	-0.5	-0.0
BMI	0.1	0.3	0.6	-0.8	-0.1
Systolic Blood Pressure	0.1	0.6	1.0	-1.0	-0.6
Allergy or Eczema	0.1	0.3	0.5	-0.7	-0.4
Respiratory disease	0.1	0.1	0.2	0.3	0.4
Chronotype (morning person)	0.1	0.1	0.2	-0.5	-0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	0.1	-0.5
Medication for hormone replacement therapy	0.1	0.2	0.2	0.3	-0.5
Diabetes (mother)	0.1	0.2	0.3	0.1	0.6
Trunk fat percentage	0.1	0.4	0.5	-0.6	0.7
Relative age voice broke	0.1	0.1	0.2	0.3	-0.4
Age when periods started (menarche)	0.1	0.2	0.4	-0.1	0.7
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.5	0.1
Medication: Levothyroxine sodium	0.1	0.2	0.4	0.1	0.6
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.3	-0.5
Body mass index (BMI)	0.1	0.5	1.0	-1.0	-0.1
Nervous feelings	0.1	0.2	0.3	0.6	0.1
Had menopause	0.1	0.2	0.3	0.5	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	0.6	-0.0
Pain all over the body in last month	0.1	0.1	0.1	0.1	0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	0.3	0.3
Arm fat percentage (right)	0.1	0.3	0.4	-0.5	0.6
Number of live births	0.1	0.1	0.1	-0.3	-0.4
Noisy workplace	0.1	0.2	0.3	0.2	0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.5	0.7	0.0
Length of working week for main job	0.1	0.2	0.2	0.4	0.4
Tense / ‘highly strung’	0.1	0.2	0.4	-0.1	0.6
Loud music exposure frequency	0.1	0.1	0.2	0.0	-0.5
Number of full brothers	0.1	0.1	0.3	-0.5	0.1
Shortness of breath walking on level ground	0.1	0.1	0.1	0.3	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.2	-0.4	0.4
Arm fat percentage (left)	0.1	0.5	1.0	-0.1	1.0
Breast cancer (self-reported)	0.1	0.1	0.2	0.4	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.2	0.3	0.0	-0.6
Wears glasses or contact lenses	0.1	0.1	0.2	0.4	0.0
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.2	0.3	0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	-0.4	0.0
Bipolar Disorder (2018)	0.0	0.0	0.0	-0.1	-0.1
Alzheimer’s Disease (in mother)	0.0	0.0	0.0	0.2	0.2
Alzheimer’s Disease (in father)	0.0	0.0	0.1	0.1	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.0	-0.1	0.1
Schizophrenia (2014)	0.0	0.1	0.1	-0.3	0.3
Hair Pigment	0.0	0.1	0.2	-0.2	0.5
Systolic blood pressure, automated reading	0.0	0.0	0.1	-0.1	-0.3
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.1	0.0	0.3
Allergy	0.0	0.1	0.2	0.4	0.1
Alcohol intake versus 10 years previously	0.0	0.0	0.1	-0.2	-0.1
Asthma	0.0	0.1	0.2	0.4	0.1
Pulse wave Arterial Stiffness index	0.0	0.0	0.1	0.3	-0.0
High blood pressure (siblings)	0.0	0.0	0.0	0.1	-0.0
Had major operations	0.0	0.0	0.0	-0.2	-0.2
Eye problems/disorders: Cataract	0.0	0.0	0.0	0.2	-0.1
Osteoarthritis (self-reported)	0.0	0.0	0.0	0.0	-0.0
Ever taken oral contraceptive pill	0.0	0.0	0.1	0.1	-0.3

Hub : Genes

MYO1F

Models

Trait associations