Hub : Genes

CLIC5

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1660	0.0360	4.9e-12	0.083	0.113	0.095	0.105	0.088	2.6e-10	1.3e-13	1.3e-11	8.9e-13	7.6e-11
2	GTEx	Muscle Skeletal	0.1336	0.0387	7.0e-05	0.077	NA	0.051	NA	0.063	5.7e-08	NA	9.3e-06	NA	7.8e-07
3	GTEx	Nerve Tibial	0.1729	0.0596	1.4e-03	0.041	NA	0.096	NA	0.090	6.3e-04	NA	2.6e-07	NA	5.9e-07
4	GTEx	Testis	0.3980	0.0740	4.9e-08	0.168	NA	0.199	NA	0.204	6.7e-08	NA	3.2e-09	NA	2.0e-09
5	GTEx	Thyroid	0.0840	0.0310	4.0e-03	0.062	NA	0.063	NA	0.060	1.7e-05	NA	1.3e-05	NA	2.3e-05
6	YFS	Blood	0.1433	0.0232	0.0e+00	0.105	0.092	0.100	0.108	0.109	1.3e-32	1.2e-28	4.2e-31	2.1e-33	7.3e-34
7	TCGA	Glioblastoma Multiforme	0.2680	0.1050	3.6e-03	-0.009	0.082	0.010	NA	-0.007	8.8e-01	1.8e-03	1.5e-01	NA	6.2e-01
8	TCGA	Brain Lower Grade Glioma	0.0648	0.0223	3.0e-05	0.002	0.023	0.022	NA	0.008	2.0e-01	1.1e-03	1.2e-03	NA	3.8e-02
9	TCGA	Prostate Adenocarcinoma	0.0737	0.0336	9.1e-03	-0.001	0.010	0.000	NA	-0.003	4.0e-01	2.8e-02	3.2e-01	NA	9.7e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.8	1.3	4.8	0.5	-1.6	-1.1	2.2	0.1	0.2	-1.3	-0.9	-0.7
Bipolar Disorder or Schizophrenia	1.3	3.3	8.3	-1.8	-1.2	-1.8	1.3	-1.7	-1.4	-2.9	-2.2	1.3
Depressed Affect (Nagel 2018)	0.5	1.0	2.2	-1.4	-1.5	1.0	0.1	0.7	1.2	0.5	-0.4	-1.2
Depression (Nagel 2018)	1.3	1.9	6.7	-2.6	-2.1	-0.8	1.1	-0.9	0.3	-1.1	-1.4	-0.2
Intelligence (Savage-Jansen 2018)	1.0	3.0	7.6	2.7	1.2	0.3	-1.1	1.4	0.9	2.8	2.6	-0.4
Neuroticism (Nagel 2018)	0.6	1.3	3.0	-1.7	-0.7	1.2	-1.3	1.6	1.2	1.1	0.1	-0.6
Schizophrenia (2018)	1.9	3.9	7.7	-2.8	-0.2	-1.5	-0.0	-2.3	-2.0	-2.6	-2.1	2.2
Schizophrenia vs Biploar Disorder	0.8	1.1	5.0	-1.1	0.1	-0.6	-0.4	-0.7	-0.9	-1.0	-0.9	2.2
Worry (Nagel 2018)	0.7	1.4	9.1	-3.0	-0.4	0.4	-1.1	0.1	0.2	-0.4	-0.9	0.9
Alzheimer’s Disease (in mother)	1.2	1.4	4.5	0.6	0.4	-0.1	-0.5	2.1	1.9	1.6	0.7	0.6
Alzheimer’s Disease (in father)	1.3	1.4	3.8	0.5	-1.9	0.5	1.6	1.2	1.4	-0.8	-0.4	-1.2
Alzheimer’s Disease (including proxy)	1.5	2.1	9.1	0.8	-0.6	0.5	-0.1	3.0	2.6	1.2	0.6	-0.1
Crohns Disease (2017)	0.6	1.3	3.7	-0.7	-1.9	-0.4	0.9	-1.5	-0.1	-1.1	-1.3	1.1
Irritable Bowel Disease (IBD)	0.1	0.3	1.9	0.2	-1.4	-0.5	0.1	-0.7	0.1	0.1	-0.3	0.3
Ulcerative Colitis (UC)	0.1	0.3	0.7	0.8	-0.4	-0.3	-0.3	0.5	0.2	0.9	0.6	-0.3
Major Depression (MDD)	1.8	2.2	6.1	-2.5	-1.1	-0.4	0.4	-1.7	0.4	-1.4	-2.2	-1.6
Reaction Time	0.6	1.2	4.2	-1.2	-2.0	-0.1	0.8	-1.0	0.9	0.1	-1.2	0.9
Verbal and Numeric Reasoning (VNR)	1.8	4.3	13.4	2.8	1.8	0.8	-1.3	2.2	-0.1	2.6	3.7	-0.8
Breast Cancer	1.2	3.0	6.5	-2.0	-1.4	-2.5	1.8	-2.3	-0.4	-1.4	-1.5	1.0
Ovarian Cancer	1.3	1.8	4.6	-0.7	-1.8	-0.7	2.1	-1.4	-0.7	-1.0	-1.5	1.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	1.8	2.7	10.8	3.3	1.1	1.2	-0.8	2.0	0.1	1.9	1.2	-0.9
Bipolar Disorder (2011)	4.0	3.9	10.5	-2.5	-1.1	-2.0	1.8	-1.4	-0.5	-3.2	-2.7	-0.1
Body Mass Index (BMI) (2010)	1.1	1.5	4.8	-0.8	-2.2	-0.4	1.2	-1.3	0.9	-0.8	-1.5	-1.2
Coronary Artery Disease (CAD)	0.3	0.3	0.8	-0.9	0.3	0.5	-0.2	0.4	0.9	-0.2	-0.8	0.0
Crohns Disease (2012)	0.6	1.0	3.8	0.0	-2.0	0.5	0.6	-1.0	0.4	-1.3	-1.4	-0.3
Mean Putamen Volume	0.6	0.7	2.0	-1.4	-0.1	-0.2	0.2	-1.1	0.9	-0.2	-0.8	1.3
Fasting Glucose	0.9	1.1	2.1	-1.1	0.7	1.0	-1.4	-0.7	-1.4	-1.0	0.1	1.4
HbA1C	0.7	0.8	2.8	1.2	-0.4	0.2	1.1	-0.4	-0.3	0.5	1.0	1.7
HDL Cholesterol	0.5	0.8	4.7	0.8	0.5	0.4	-0.9	-0.3	0.8	0.3	0.5	-2.2
LDL Cholesterol	0.3	0.5	1.5	-1.2	0.8	-0.7	-1.1	0.1	-0.4	0.0	0.2	0.3
Lupus	0.9	1.3	8.2	-0.2	-0.2	0.4	-1.1	-0.8	2.9	1.0	-0.4	-0.3
Neuroticism (2016)	1.0	1.5	3.2	0.3	-1.6	1.3	-1.4	1.8	1.3	0.7	0.1	-1.3
Primary Biliary Cirrhosis	0.5	0.7	2.5	-0.6	-1.6	-0.3	-0.1	-1.3	0.2	-0.2	-0.5	1.2
Rheumatoid Arthritis	0.5	0.8	1.7	-0.8	0.1	1.3	-0.5	-0.8	1.0	-1.0	-1.1	0.3
Schizophrenia (2014)	1.0	2.1	5.8	-2.4	-0.3	-0.8	-0.5	-1.5	-1.0	-1.9	-1.5	1.9
Triglycerides	0.1	0.2	0.6	0.6	0.1	-0.0	-0.4	0.7	0.2	0.8	-0.0	0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.5	-0.9	-0.8	-0.3	-0.7	-1.0	-1.6	-0.3	-0.7	0.1
Ulcerative Colitis	0.1	0.2	0.8	-0.5	-0.3	-0.2	-0.3	0.2	0.5	-0.1	-0.5	0.9
Blood Eosinophil Count	0.4	3.3	10.3	-1.1	-1.1	0.4	3.2	-1.7	-1.8	-1.8	-1.4	2.3
Blood Platelet Count	0.0	0.5	1.1	-0.2	0.5	0.4	-0.9	1.1	0.6	0.7	0.2	1.0
Blood Red Count	0.4	3.5	15.8	4.0	0.2	0.5	1.4	1.2	0.3	2.2	2.7	0.5
Blood White Count	0.5	3.5	6.1	-1.4	-0.4	-2.5	2.4	-2.4	-1.1	-1.7	-1.6	2.4
Heel T-Score	1.7	13.2	31.1	3.1	4.5	-1.3	-5.6	-0.6	4.6	4.0	3.2	2.8
BMI	0.4	2.3	5.6	2.4	0.9	0.1	1.2	0.9	1.4	0.8	2.2	2.1
Height	0.2	2.9	17.1	-0.8	-1.3	4.1	-0.1	2.2	-0.7	-0.0	-0.7	-1.0
Waist Hip Ratio (WHR)	1.3	5.7	13.9	-2.3	-2.6	-2.5	3.7	-1.5	-2.3	-2.1	-2.8	0.0
Systolic Blood Pressure	0.7	3.6	8.4	-2.9	-2.0	-1.5	1.3	-0.7	-1.6	-2.9	-2.1	0.7
Smoking Status	0.4	0.9	3.4	0.8	1.1	-1.8	0.2	-1.0	-1.0	0.6	0.1	0.8
Allergy or Eczema	0.9	2.3	11.2	0.3	-1.1	-0.4	3.3	-0.8	-2.0	-1.6	-0.8	0.8
Cardiovascular Disease	0.5	1.8	6.0	-2.5	-1.2	-0.8	0.5	-1.0	-0.4	-2.0	-0.9	1.1
Hypothyroidism (self reported)	1.3	3.0	13.2	1.1	-1.6	1.4	-1.4	2.0	3.6	0.9	0.2	1.3
Respiratory disease	0.4	0.8	2.0	-0.8	-1.4	0.5	1.2	0.6	-1.2	-0.2	-0.4	-0.9
Type 2 Diabetes (T2D) (2018)	0.6	1.1	6.2	2.5	-0.5	-0.6	0.7	1.2	0.8	0.4	0.1	0.8
Lung FEV1/FVC ratio	1.8	8.9	25.0	2.2	2.4	5.0	-2.0	3.6	3.6	2.8	2.7	-0.6
Lung FVC	0.7	3.5	17.2	-2.2	1.6	-0.7	-4.1	-0.5	1.1	0.7	1.2	1.5
Neuroticism	0.7	1.7	4.8	-0.5	-0.9	1.5	-1.1	2.2	1.0	1.7	1.0	-1.2
Chronotype (morning person)	2.4	5.4	13.7	-0.9	3.2	2.3	-3.7	2.9	0.4	1.9	2.1	1.6
Hair Pigment	0.7	20.9	62.1	2.8	6.5	2.7	-7.9	2.3	3.8	4.2	5.4	1.2
Tanning	0.1	1.2	3.7	-0.1	-1.9	-0.3	1.9	0.6	0.9	-0.9	-0.5	-1.1
Hand grip strength (left)	0.2	0.4	0.9	-0.5	0.8	-0.9	-0.5	0.3	-0.5	-0.9	0.4	0.7
Number of treatments/medications taken	0.4	0.7	1.8	-1.4	-0.7	1.1	-0.2	0.8	-0.7	-0.3	-0.2	1.1
Average weekly spirits intake	0.4	0.5	2.4	0.2	0.3	-1.6	-0.0	-0.5	0.0	0.2	0.8	1.1
Sensitivity / hurt feelings	0.8	1.3	3.5	0.6	-0.2	0.8	-1.4	1.9	1.0	1.4	1.2	0.9
Frequency of depressed mood in last 2 weeks	1.1	1.5	6.5	-2.6	-1.9	0.1	0.5	0.1	0.5	-1.0	-0.9	0.9
Hearing difficulty/problems: Yes	1.4	2.2	8.1	-0.9	1.5	1.9	-2.8	0.8	1.4	1.3	0.6	-0.7
Relative age of first facial hair	0.1	0.2	0.5	-0.1	0.5	0.7	-0.7	0.5	-0.2	0.2	0.6	0.3
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.4	-0.3	0.9	1.9	-1.2	0.5	1.0	0.5	1.0	-0.8
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.1	-0.5	-1.3	2.0	-0.9	0.5	1.4	1.0	-0.4	-0.7
Ever had hysterectomy (womb removed)	0.6	0.7	3.3	0.1	-0.3	-1.3	-0.1	0.1	1.1	1.8	-0.4	-0.0
Systolic blood pressure, automated reading	0.3	0.8	2.6	-1.2	-0.9	0.2	0.7	1.0	-1.6	-0.6	-0.7	-0.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.0	1.4	0.3	0.7	-0.7	0.8	1.1	0.6	0.7	-0.1
Angina	0.4	0.5	1.9	-0.3	-0.7	1.0	1.4	0.6	0.8	0.2	0.2	0.6
Medication for hormone replacement therapy	0.2	0.2	0.4	-0.7	-0.4	0.3	0.6	0.3	-0.5	-0.5	-0.3	0.6
Vitamin and mineral supplements	0.9	1.2	5.2	1.6	-0.1	2.3	0.5	0.3	0.2	0.4	0.2	-1.5
Supplements: Zinc	1.1	1.2	3.2	-1.8	0.5	-0.8	-1.6	-1.5	-1.0	-0.3	-0.8	0.7
Medication: Co-codamol	0.5	0.6	4.2	-0.7	0.0	-0.3	-0.3	0.1	2.0	-0.1	-0.2	0.2
Medication: Metformin	0.7	1.0	2.7	-0.2	-1.1	-1.2	0.5	-1.0	-0.6	-0.8	-1.3	1.7
Diabetes (father)	0.3	0.4	1.5	-0.6	0.0	-0.7	-1.1	0.1	1.2	0.1	-0.1	0.3
Diabetes (mother)	0.4	0.4	1.4	-0.5	-0.1	-1.2	-0.2	-1.0	-0.8	-0.6	0.0	0.6
Severe depression (siblings)	0.6	0.7	2.2	1.5	-0.4	-0.2	1.5	0.6	-0.9	0.5	0.2	-0.5
Pack years adult smoking proportion	1.3	2.0	6.4	0.1	0.8	-1.9	-0.6	-2.5	0.2	-0.8	0.4	2.5
Impedance of leg (right)	0.4	1.9	5.0	-1.6	-0.3	-1.1	-0.5	-1.0	-1.9	-1.0	-1.6	-2.2
Leg fat-free mass (left)	0.4	2.2	7.1	1.4	-0.5	2.7	1.1	2.1	1.6	0.7	1.2	0.2
Trunk fat percentage	0.2	1.0	3.5	0.0	-1.1	0.7	1.7	0.4	0.3	-1.9	0.1	0.7
Hand grip strength (right)	0.1	0.3	0.9	-0.5	0.7	-0.4	-0.1	-0.0	0.4	-0.9	-0.2	0.7
Townsend deprivation index at recruitment	0.3	0.4	1.1	-1.0	-0.7	-0.2	0.8	0.0	-1.1	-0.2	-0.3	0.6
Current tobacco smoking	0.7	1.1	3.2	-0.0	1.1	-1.5	0.1	-0.9	-1.5	0.1	0.3	1.8
Average weekly fortified wine intake	1.4	1.6	5.9	0.1	0.9	0.4	-0.8	1.3	0.8	0.4	2.1	2.4
Maternal smoking around birth	0.3	0.4	1.0	-1.0	-0.2	-1.0	0.3	-0.5	-0.5	-1.0	-0.6	-0.3
Fed-up feelings	1.2	2.2	7.8	-1.4	-2.8	0.0	1.5	-0.4	0.5	-1.4	-1.7	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.0	-1.4	-1.1	-0.9	0.9	-0.2	-0.3	-0.7	-0.6	0.8
Relative age voice broke	1.0	1.6	6.8	-0.7	1.0	1.0	-1.2	1.5	0.3	0.2	0.9	2.6
Taking other prescription medications	0.6	1.0	3.6	-0.9	-1.9	0.9	1.1	0.1	0.1	-0.5	-1.3	-0.7
Age when periods started (menarche)	0.9	2.1	5.4	-2.1	-1.0	-0.5	0.9	-1.7	-1.2	-1.6	-2.3	-0.3
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.3	-0.3	-0.8	0.6	-1.0	0.1	0.5	0.5	1.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.8	0.5	1.7	-0.1	-1.2	0.5	0.3	1.2	0.6	1.1
Tinnitus: Yes, but not now, but have in the past	2.8	2.9	7.1	-2.4	-1.1	-1.6	1.8	-0.4	-1.0	-2.7	-2.1	0.8
Qualifications: CSEs or equivalent	1.3	1.7	5.6	-2.4	-0.3	-0.5	-0.9	-1.6	1.2	-1.6	-0.5	1.3
Serious illness, injury or assault to yourself	0.3	0.4	2.2	-0.6	-0.1	1.5	0.1	-0.2	0.1	0.6	0.4	0.1
High blood pressure	0.3	0.9	4.6	-2.1	-0.5	-0.8	-0.1	-0.8	-0.5	-1.4	-0.2	-0.2
Hayfever, allergic rhinitis or eczema	1.1	2.5	9.9	-0.6	-1.6	-0.6	3.1	-1.1	-1.6	-1.9	-0.9	0.9
Multivitamins +/- minerals	0.5	0.6	1.7	-1.3	-0.3	-1.3	0.0	-0.0	0.7	-0.5	-0.5	0.9
Stomach or abdominal pain in last month	0.9	1.1	6.4	0.1	-0.9	2.5	-0.6	-0.2	1.4	0.1	0.1	0.0
Supplements: Glucosamine	0.7	0.9	2.2	0.4	-1.1	1.4	0.3	1.5	0.4	-0.1	0.7	1.5
Diverticular disease/diverticulitis (self-reported)	1.1	1.2	3.8	-2.0	-0.5	-0.4	0.0	-0.4	0.8	-1.0	-1.7	-1.5
Medication: Atenolol	3.1	3.8	8.8	-1.7	-1.1	-2.5	1.6	-2.7	-1.0	-3.0	-1.8	1.2
Medication: Levothyroxine sodium	1.7	2.9	12.7	1.4	-0.6	1.1	-1.6	0.8	3.6	1.6	0.5	2.0
Sitting height	0.5	3.2	12.9	-0.5	0.9	3.6	-1.8	2.0	2.0	1.5	1.1	-0.5
Chronic bronchitis/emphysema (father)	0.7	0.8	2.9	-0.3	-0.8	-0.1	1.3	-0.9	-1.7	-0.3	-0.7	-0.1
High blood pressure (mother)	1.5	2.1	6.0	-2.4	-1.8	-1.1	0.8	-0.6	-1.7	-1.2	-1.4	-1.0
Body mass index (BMI)	0.3	1.1	2.7	1.1	-0.4	0.8	1.1	0.8	1.1	-0.3	1.3	1.6
Impedance of leg (left)	0.4	1.9	4.0	-1.7	0.3	-1.0	-0.9	-0.9	-1.9	-1.1	-1.6	-2.0
Leg predicted mass (left)	0.4	2.2	7.1	1.4	-0.5	2.7	1.1	2.1	1.7	0.7	1.2	0.2
Trunk fat mass	0.2	0.9	2.9	0.3	-1.0	1.3	1.7	0.8	0.6	-1.3	0.3	0.3
Waist circumference	0.3	0.9	4.5	0.3	-0.7	0.2	2.1	0.3	-0.3	-1.2	0.6	1.2
Number of incorrect matches in round	0.8	1.3	3.3	-1.5	0.7	-0.4	-1.8	-1.3	0.8	0.0	-0.2	1.7
Past tobacco smoking	0.4	0.8	2.2	-1.2	-0.5	-0.3	0.1	-1.5	0.4	-1.2	-0.9	0.9
Alcohol usually taken with meals	2.1	3.5	8.1	1.5	2.9	2.3	-2.0	0.7	-0.0	1.7	2.0	1.9
Nervous feelings	1.3	2.4	9.2	-3.0	-1.8	-0.2	1.1	0.1	-0.2	-1.6	-1.8	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.3	-1.1	-0.9	1.5	-0.6	-0.4	0.8	0.1	-0.8	-1.0
Hearing difficulty/problems with background noise	1.2	2.0	7.9	-0.7	1.8	0.7	-2.8	0.8	0.8	1.4	0.8	-1.4
Hair/balding pattern: Pattern 2	2.0	2.5	6.2	1.0	1.5	2.0	-1.4	2.4	-0.5	0.7	2.5	-0.8
Had menopause	0.5	0.7	1.7	0.6	-0.2	0.5	-0.8	1.2	1.3	0.3	-0.3	-1.3
Had other major operations	1.7	2.1	4.8	0.7	2.0	1.4	-0.8	1.1	0.3	1.5	1.8	2.2
Forced vital capacity (FVC)	0.3	1.1	5.0	-1.2	0.4	0.7	-2.2	0.5	0.4	1.0	0.5	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.3	1.2	1.1	-0.0	-1.2	0.0	-0.1	1.5	0.7	1.5
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.5	0.7	0.3	-0.3	0.9	-0.3	-1.9	0.1	-0.5	-0.3
Qualifications: None of the above	0.4	0.8	2.0	-1.4	-1.2	-0.1	-0.2	0.0	-1.0	-0.7	-1.4	-0.2
Financial difficulties in last 2 years	0.3	0.4	1.6	-0.9	0.1	-0.1	-0.8	0.4	1.3	0.1	-0.3	0.6
Mouth/teeth dental problems	2.7	4.1	16.8	2.7	4.1	0.9	-1.8	0.6	-1.2	1.4	2.3	0.2
Heart attack	0.5	0.6	1.8	-0.4	1.2	0.5	-1.3	0.5	1.3	-0.3	0.3	-0.0
Allergy	0.8	1.9	8.5	0.6	1.6	0.4	-2.9	0.2	1.8	1.4	0.8	-0.2
Pain all over the body in last month	1.0	1.1	2.3	-1.5	-1.3	0.7	1.2	-0.9	-0.2	-0.6	-1.4	-0.7
Diabetes (self-reported)	0.7	1.1	5.6	2.4	0.3	-0.9	0.1	0.3	-0.2	0.8	0.6	1.3
Hayfever/allergic rhinitis (self-reported)	2.4	3.2	7.9	-1.8	-1.9	0.6	2.4	-1.4	-1.5	-2.8	-2.0	0.5
Medication: Ramipril	0.6	0.8	3.5	-1.9	-0.4	-1.0	0.4	-0.4	0.2	-1.0	-0.9	-0.3
Medication: Simvastatin	0.5	0.7	1.7	-1.3	-0.2	-1.0	0.1	0.1	0.1	0.9	-1.3	0.8
Fluid intelligence score	2.9	6.1	11.7	2.7	2.3	2.5	-2.1	3.1	1.3	2.9	3.4	-0.8
Illnesses of siblings	2.3	3.2	12.7	1.9	3.6	-0.5	-1.9	0.8	-0.9	1.4	2.0	1.1
Neuroticism score	0.3	0.7	1.7	-0.6	-1.3	1.2	-0.5	1.2	0.6	0.5	0.4	-0.6
Weight	0.3	1.5	4.6	0.9	-0.7	2.1	1.1	1.6	1.3	-0.0	1.1	0.8
Impedance of arm (right)	0.4	1.7	4.1	-1.0	-1.5	-0.9	1.3	-1.2	-1.3	-2.0	-1.4	-0.9
Arm fat percentage (right)	0.4	1.4	5.8	0.5	-1.2	-0.0	2.4	-0.2	0.1	-1.9	0.3	1.3
Trunk fat-free mass	0.2	0.9	4.3	0.7	-0.1	2.1	0.6	1.3	0.7	0.8	0.5	-0.4
Hip circumference	0.5	2.3	4.5	1.3	-0.4	2.1	1.0	1.7	2.1	-0.5	1.4	2.0
Time employed in main current job	1.1	1.3	4.8	-1.1	1.1	-0.6	-0.2	-0.6	-2.2	-1.1	-0.1	1.6
Alcohol intake versus 10 years previously	0.2	0.3	1.1	-0.0	-1.1	-0.6	0.7	-0.4	0.5	0.3	0.1	0.0
Father’s age at death	0.2	0.3	1.4	0.3	0.2	-1.2	0.3	0.5	0.2	0.5	0.5	0.2
Worrier / anxious feelings	0.7	1.4	4.1	-0.7	0.5	1.5	-2.0	2.0	-0.0	1.2	0.2	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	4.8	-1.1	-2.2	0.5	1.1	0.4	1.4	0.3	-0.6	1.1
Falls in the last year	2.5	3.4	8.4	1.2	2.6	1.2	-1.9	1.1	-0.3	1.7	2.2	2.9
Hair/balding pattern: Pattern 3	1.5	2.2	5.0	-0.7	-1.0	-2.1	1.7	-1.3	-2.2	-1.3	-0.7	1.2
Number of live births	0.6	0.8	3.4	0.6	-0.5	0.5	1.0	0.9	-1.8	-0.7	0.0	0.8
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	8.1	-0.3	0.8	2.9	-2.5	2.0	1.7	2.2	1.4	-1.2
Pulse rate	1.1	1.9	5.5	-1.8	-0.8	-0.8	-0.6	-2.3	0.6	-1.9	-1.6	-0.6
Happiness	1.0	1.3	3.8	-1.4	-0.7	1.3	0.9	0.8	0.6	-0.6	-1.1	-1.9
Noisy workplace	0.8	1.0	4.2	-0.0	-0.3	-1.6	-0.5	-2.0	-1.4	-0.1	-0.1	0.7
Qualifications: A levels/AS levels or equivalent	1.1	2.5	12.5	3.5	1.1	0.9	-0.6	0.9	0.2	1.6	1.9	-0.7
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	4.1	-1.0	-0.3	2.0	-0.8	1.6	1.0	0.2	1.3	0.2
Mouth/teeth dental problems: Dentures	1.0	1.6	4.5	-2.1	-0.8	-1.0	-0.0	-0.8	0.5	-1.8	-1.4	1.6
Asthma	0.6	1.2	3.9	0.5	-1.5	0.4	2.0	0.6	-1.2	-0.4	-0.5	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.4	0.4	-0.5	-0.5	0.6	0.1	-0.3	-0.6	1.2	0.5
Medication: Cholesterol lowering	0.7	1.0	2.4	-0.9	-1.1	-1.6	0.8	-0.7	0.4	-1.0	-0.5	1.5
Depression (self-reported)	0.6	0.7	1.9	-1.4	0.6	0.6	-0.2	0.9	0.6	-1.0	-0.0	1.2
Medication: Lansoprazole	0.8	0.9	2.8	-1.0	-1.7	0.7	1.1	0.7	0.1	-0.5	-1.0	-0.7
Prospective memory result	1.4	1.7	8.3	-1.0	0.0	-1.9	-0.4	-1.4	-0.4	-0.7	0.1	2.9
Lung cancer (father)	0.3	0.3	1.1	0.7	0.4	0.0	0.3	1.0	0.2	0.6	0.5	0.6
Illnesses of mother	1.0	1.3	4.1	2.0	1.3	1.7	-0.6	0.5	0.3	1.2	0.7	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	13.0	-0.2	1.8	2.9	-3.6	1.9	2.2	3.0	1.8	-0.7
Pulse wave Arterial Stiffness index	1.1	1.3	2.7	0.8	-1.3	0.1	1.3	-1.7	-1.3	-0.7	-1.0	-1.4
Impedance of arm (left)	0.3	1.3	3.6	-1.0	-1.4	-0.6	0.9	-1.0	-0.9	-1.9	-1.2	-0.6
Arm fat mass (right)	0.3	1.1	3.4	0.7	-0.8	0.9	1.9	0.6	0.6	-1.2	0.7	1.3
Trunk predicted mass	0.2	0.9	4.0	0.6	-0.0	2.0	0.6	1.2	0.8	0.8	0.4	-0.4
Standing height	0.2	2.1	10.6	-0.4	-0.5	3.2	0.1	1.8	0.4	0.5	-0.3	-2.0
Length of working week for main job	1.6	1.8	5.4	2.1	0.0	0.7	-0.2	1.6	0.7	2.3	0.7	-1.3
Exposure to tobacco smoke at home	0.6	0.7	3.6	1.9	0.4	0.2	-0.2	-0.6	-0.7	0.1	1.0	0.5
Breastfed as a baby	0.6	0.7	3.0	-0.3	-1.1	0.6	1.7	-0.3	0.2	-0.9	-0.7	0.6
Tense / ‘highly strung’	0.9	1.5	5.3	-2.3	-1.3	0.1	0.1	-0.6	0.0	-1.4	-1.4	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.5	-0.1	-0.4	-1.2	0.2	1.6	1.5	0.7	-0.2	-0.5
Hair/balding pattern: Pattern 4	0.7	1.6	8.2	-0.4	-2.9	-0.5	1.3	-0.5	0.8	-1.3	-1.1	-0.3
Birth weight of first child	0.1	0.2	0.6	0.2	-0.1	0.2	0.2	-0.5	0.1	-0.8	-0.6	0.1
Peak expiratory flow (PEF)	1.4	3.2	10.7	0.4	0.9	3.3	-2.6	1.4	1.5	2.1	1.1	-0.6
Pulse wave reflection index	1.6	1.9	5.2	2.2	-1.7	-0.1	1.9	0.3	-0.7	0.0	-0.2	-2.3
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.3	0.4	0.0	0.5	-0.1	-0.7	-0.9	-0.4	1.1	0.1
Loud music exposure frequency	1.0	1.1	3.0	-0.1	-0.6	-0.9	1.3	-1.3	-1.7	-1.1	-0.6	-0.5
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	4.8	1.1	0.3	0.3	0.8	-0.1	-0.4	0.7	0.0	-2.2
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	9.9	-0.2	-3.1	0.3	1.2	1.2	1.2	-0.6	-1.4	-0.5
Blood clot in the leg (DVT)	0.6	0.7	2.6	-0.4	-1.6	0.4	0.5	0.7	1.6	0.1	0.1	-0.6
Medication: Paracetamol	0.8	1.4	6.6	-1.6	0.8	-0.3	-0.6	0.4	0.6	1.3	0.2	2.6
Headache pain in last month	0.8	1.3	5.2	-0.6	-1.1	0.5	0.6	-0.0	1.6	1.2	-0.6	2.3
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	3.6	1.9	1.3	1.9	-0.2	1.4	-0.0	1.7	0.7	-0.6
Glaucoma (self-reported)	2.7	3.2	8.0	2.8	0.1	2.1	0.6	2.3	-0.1	1.6	2.7	-0.7
Gout (self-reported)	1.0	1.3	5.2	0.8	-2.3	-1.0	1.4	-0.9	0.2	-1.4	-0.1	0.3
Hypothyroidism/myxoedema (self-reported)	1.8	3.6	10.8	1.8	-1.0	2.0	-1.6	2.2	3.3	1.7	0.8	1.4
Medication: Amlodipine	0.8	1.1	4.9	-0.8	-0.6	-2.2	-0.6	-1.2	-1.3	-0.7	0.1	0.6
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.8	-0.7	-0.0	0.3	1.6	0.9	-2.0	-0.1	-0.0	1.1
Birth weight	1.9	4.1	8.2	-2.6	-0.9	-0.8	0.9	-2.7	-2.1	-2.9	-2.7	0.0
Chronic bronchitis/emphysema (mother)	0.8	0.9	3.3	-0.1	0.7	-1.8	0.8	-0.4	-1.7	-0.4	-0.3	0.8
High blood pressure (siblings)	0.7	1.0	3.1	-1.6	-1.8	0.3	0.5	0.0	0.3	-0.8	-1.0	-0.9
Forced vital capacity (FVC), Best measure	0.8	2.8	9.9	-0.7	1.5	1.6	-3.1	1.3	1.1	2.3	1.2	-0.6
Body fat percentage	0.2	0.7	2.4	0.1	-0.9	0.5	1.5	0.3	0.2	-1.6	0.2	0.8
Leg fat percentage (right)	0.1	0.4	1.0	0.3	-0.5	0.2	1.0	0.5	-0.3	-0.6	0.5	1.0
Arm fat-free mass (right)	0.3	1.6	6.2	0.9	0.3	2.5	0.1	1.8	1.6	0.9	0.5	-0.8
Exposure to tobacco smoke outside home	1.4	1.8	8.8	0.1	1.3	-0.2	-1.1	1.1	-0.7	0.4	1.6	3.0
Comparative body size at age 10	0.6	1.8	10.4	3.2	0.6	-0.3	-0.1	-0.3	1.2	0.1	1.9	-0.2
Number of full brothers	0.9	1.1	2.3	-1.5	-0.2	-0.7	-1.2	-1.4	0.8	-0.5	-1.5	0.8
Worry too long after embarrassment	0.6	1.0	2.3	0.3	0.3	1.4	-1.1	1.4	-0.5	0.7	1.5	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.9	-0.4	-0.0	-0.7	0.9	-0.4	-0.2	-1.0	-0.1	0.1
Wheeze or whistling in the chest in last year	1.0	1.8	3.3	0.2	1.8	1.2	-0.2	1.3	-1.6	1.8	1.6	1.4
Number of children fathered	0.2	0.2	1.4	0.3	-0.1	0.3	-0.0	0.2	0.5	0.0	-0.1	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.1	0.4	0.5	0.3	-0.2	-0.4	-1.1	-0.5	0.3	0.4
Age at first live birth	0.4	0.7	3.1	0.8	0.2	0.5	1.8	-0.6	-0.8	-0.7	0.2	-0.5
Pulse wave peak to peak time	1.0	1.2	2.7	-0.8	1.3	0.1	-1.2	1.7	1.3	0.7	0.9	1.1
Health satisfaction	1.6	2.1	6.1	-0.9	-2.4	0.7	2.5	0.7	0.6	-1.6	-1.1	0.9
Shortness of breath walking on level ground	0.5	0.6	2.3	0.4	-0.7	1.5	0.7	0.8	1.1	-0.1	0.4	0.4
Qualifications: College or University degree	0.9	2.8	12.7	3.6	0.3	1.2	0.6	1.7	0.4	1.7	1.6	-1.6
Eye problems/disorders: None of the above	0.6	0.7	3.8	-0.8	-0.5	-0.3	-0.3	0.5	0.3	0.5	-1.0	-1.9
Mouth/teeth dental problems: Loose teeth	1.1	1.3	4.0	-1.1	-2.0	-0.4	0.9	-0.9	-0.4	-1.7	-0.1	-1.3
Emphysema/chronic bronchitis	0.3	0.3	1.2	0.2	-0.0	0.4	-0.2	0.5	-1.0	-0.6	0.1	-1.1
Medication for pain relief, constipation, heartburn	0.5	0.8	3.1	1.7	0.3	-0.5	-0.5	-0.1	0.8	0.3	-0.3	-1.8
Neck or shoulder pain in last month	0.4	0.6	1.6	-0.3	-0.9	-0.9	1.2	-0.3	-0.3	0.2	-0.8	1.3
Medication: Blood pressure	0.6	1.1	4.1	-0.7	-0.6	-2.0	-0.0	-1.6	-0.0	-1.4	0.1	0.3
Angina (self-reported)	0.3	0.5	1.3	-0.2	-0.7	0.9	1.1	0.4	1.0	0.2	0.2	0.6
Migraine (self-reported)	1.9	2.3	5.8	-2.2	-2.4	-0.2	2.0	0.0	0.3	-2.3	-0.8	0.6
Medication: Ibuprofen	0.5	0.6	3.4	0.9	0.4	-0.2	-0.4	0.7	0.3	0.4	1.8	0.5
Medication: Allopurinol	0.8	1.1	3.5	1.7	-1.9	-0.4	1.4	0.3	-0.0	-0.8	0.4	-0.4
Medication: Omeprazole	0.8	0.9	3.0	-0.9	0.5	1.7	-1.3	-0.9	0.5	-0.6	0.5	1.0
Medication: Seretide 50 evohaler	0.5	0.6	2.3	0.1	-0.3	-1.5	1.3	-0.2	-0.7	0.4	-0.0	0.4
Mean time to correctly identify matches	0.7	1.3	4.2	-1.7	-2.0	-0.2	0.6	-1.0	0.9	0.0	-1.4	0.6
Heart disease (mother)	1.4	1.7	6.1	-1.0	-1.4	-1.2	1.3	-1.1	2.5	-0.7	-1.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.1	-0.1	0.1	0.8	-0.3	0.6	1.1	0.5	0.5	0.4
Whole body fat mass	0.2	0.9	2.5	0.6	-0.7	1.2	1.6	0.8	0.7	-1.0	0.6	0.5
Leg fat mass (right)	0.2	0.8	2.0	0.9	-0.6	1.0	1.4	1.2	0.5	-0.3	0.8	0.7
Arm predicted mass (right)	0.3	1.3	4.8	1.0	0.2	2.2	-0.0	1.5	1.4	0.8	0.5	-1.0
Pulse rate, automated reading	2.1	6.9	21.2	-1.9	-1.6	-3.7	2.0	-4.6	-1.2	-2.4	-3.1	0.1
Alcohol intake frequency.	0.2	0.6	2.1	0.1	-0.9	0.4	1.2	0.2	-0.6	-0.3	0.3	1.5
Comparative height size at age 10	0.5	2.6	8.7	0.5	-1.5	3.0	0.3	1.9	1.1	1.3	-0.7	-2.3
Number of full sisters	1.1	1.3	6.4	-2.5	-0.4	0.2	-1.5	0.4	1.4	-0.7	-0.8	0.3
Suffer from ‘nerves’	0.6	1.0	5.7	-2.4	-0.7	0.3	-0.8	0.1	0.7	-0.0	-0.8	1.1
Overall health rating	1.0	2.2	4.2	-1.5	-2.0	-0.4	2.0	-1.7	-0.1	-1.5	-2.0	0.2
Chest pain or discomfort	0.8	1.2	3.7	-1.5	-1.3	-0.9	0.4	-1.0	1.9	0.1	-1.1	-0.4
Had major operations	1.2	1.4	3.4	-1.6	-1.0	-0.9	0.6	-1.8	-0.2	-1.2	-1.9	-0.1
Age at last live birth	1.0	1.5	3.2	-0.6	-0.2	-1.4	1.7	-1.5	-1.6	-1.8	-0.6	0.1
Family relationship satisfaction	0.5	0.6	2.0	0.5	0.9	1.3	-0.7	-0.0	1.4	0.0	0.4	-0.7
Leg pain on walking	2.8	3.5	9.1	-1.0	-3.0	-0.8	2.6	-1.7	-0.3	-2.9	-1.7	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.0	-0.7	0.6	-0.8	0.0	0.5	-1.0	0.0	0.8	0.6
Commuting to job workplace: Car/motor vehicle	1.6	1.9	5.3	-0.3	2.3	1.1	-1.6	0.5	-1.4	0.8	1.6	1.5
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	7.1	2.7	0.3	-0.7	0.2	-0.2	-0.3	0.3	0.4	-0.8
Medication: Aspirin	0.7	0.9	6.7	-0.4	0.6	-0.1	-0.6	0.2	0.8	-0.2	0.2	2.6
Supplements: Vitamin C	0.9	1.1	4.0	-1.7	0.4	-1.1	-0.1	-0.2	-2.0	0.4	-0.9	-0.5
Knee pain experienced in last month	1.3	2.0	6.5	-1.0	-2.6	-0.1	2.1	-0.1	0.4	-0.9	-2.1	-0.7
Hypertension (Self-reported)	0.4	1.1	6.1	-2.5	-0.2	-0.9	-0.5	-1.1	-0.4	-1.2	-0.1	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.2	1.2	0.5	-0.0	-1.0	0.5	0.8	1.5	0.5	-1.2
Illnesses of father: Heart disease	0.5	0.7	1.6	-1.3	-0.4	-1.2	0.2	0.9	1.2	0.0	-0.7	-0.5
Illnesses of siblings: Diabetes	0.3	0.3	0.9	-0.4	-0.9	-0.6	0.9	0.0	0.2	0.2	-0.9	-0.0
Smoking status: Previous	0.6	0.9	2.8	0.9	0.5	0.4	-0.2	1.7	-0.5	1.3	0.8	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.8	-1.4	-1.7	0.8	1.5	0.1	-0.1	-0.4	-1.6	0.2
Whole body fat-free mass	0.3	1.5	6.0	1.1	-0.1	2.5	0.7	1.8	1.2	0.9	0.9	-0.2
Leg fat-free mass (right)	0.4	2.3	7.1	1.5	-0.1	2.7	1.0	2.2	1.6	0.7	1.3	0.6
Arm fat percentage (left)	0.3	1.3	4.9	0.6	-1.3	0.1	2.2	-0.1	0.5	-1.7	0.4	1.3
Average weekly red wine intake	2.9	4.3	8.0	2.3	2.3	1.9	-2.6	1.1	0.5	2.7	2.8	0.9
Handedness (chirality/laterality): Left-handed	2.9	3.5	8.2	-1.4	-2.9	-1.2	2.3	-1.0	-2.1	-2.4	-1.4	1.3
Mood swings	0.4	0.8	1.9	-0.8	-1.0	1.4	-0.2	1.0	1.0	0.9	0.5	-0.8
Loneliness, isolation	1.2	1.7	7.8	-2.8	-0.5	-0.2	0.1	-1.6	-0.4	-1.8	-1.1	0.1
Long-standing illness, disability or infirmity	0.3	0.4	1.6	-0.8	-0.5	0.3	0.5	0.0	-0.1	-0.9	0.0	1.3
Ever had bowel cancer screening	0.5	0.6	1.9	1.3	-0.0	-0.7	0.4	-0.8	-0.0	0.2	1.4	0.5
Diabetes diagnosed by doctor	0.2	0.4	1.5	1.2	-0.4	-0.5	0.3	0.4	0.4	0.3	-0.2	1.1
Ever had stillbirth, spontaneous miscarriage or termination	2.8	3.0	7.2	-1.6	-1.4	-2.0	1.6	-2.7	-1.2	-2.0	-1.6	0.7
Friendships satisfaction	0.6	0.7	1.9	-0.6	0.3	-0.8	-0.1	-1.1	0.9	-0.6	-1.0	-1.4
Qualifications: nursing, teaching	0.3	0.4	1.8	1.3	0.4	0.0	-0.2	-0.5	-0.2	1.0	0.5	0.6
Commuting to job workplace: Walk	0.7	0.8	3.8	0.7	-0.7	0.5	0.0	1.0	2.0	-0.2	0.6	-0.7
Eye problems/disorders: Cataract	0.4	0.4	1.1	0.2	0.4	0.9	-0.8	-0.3	1.0	-0.3	-0.1	1.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.9	-0.9	-1.4	0.1	-0.1	0.6	1.2	0.6	-0.1	-0.3
Medication for cholesterol	0.5	0.8	2.0	1.4	0.7	-0.9	-0.8	-1.1	1.2	-0.0	0.6	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	2.7	-0.7	-0.3	-0.4	0.1	0.2	-0.7	-0.0	0.2	1.6
Back pain experienced in last month	0.4	0.6	1.6	0.8	0.9	-1.1	-0.0	-0.9	-0.0	0.3	0.3	1.3
Mineral and other dietary supplements	0.3	0.4	2.2	1.5	0.3	0.4	0.1	-0.1	0.3	0.4	0.7	-0.7
Breast cancer (self-reported)	0.4	0.4	1.3	-0.2	0.8	0.6	-0.6	0.9	0.2	0.5	0.4	1.1
Asthma (self-reported)	0.5	1.0	2.6	0.7	-1.4	0.8	1.6	0.8	-0.9	-0.2	-0.2	-1.3
Osteoporosis (self-reported)	0.5	0.6	3.6	-0.7	-0.3	-0.9	0.3	-0.1	-0.5	-1.9	-0.4	0.1
Osteoarthritis (self-reported)	0.9	1.1	4.1	-1.2	-2.0	0.4	1.3	0.7	-0.2	-1.0	-1.1	-0.6
Medication: Aspirin	0.7	0.9	5.7	-0.0	0.5	0.3	-0.9	0.1	1.2	0.0	0.6	2.4
Medication: Gliclazide	0.6	0.7	3.7	1.1	0.6	-1.9	-0.2	-0.5	0.4	0.2	0.8	-0.4
Illnesses of father: None of the above (group 1)	1.6	2.0	6.0	1.4	1.9	1.5	-1.4	-0.1	-0.5	1.0	2.5	0.9
Smoking status: Current	0.5	0.8	2.2	0.1	0.9	-1.5	-0.1	-1.0	-1.2	-0.0	0.2	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	8.2	-1.0	1.5	0.8	-2.9	0.6	0.7	2.3	0.5	-0.5
Whole body water mass	0.3	1.4	6.0	1.0	-0.1	2.5	0.7	1.6	1.1	0.8	0.8	-0.3
Leg predicted mass (right)	0.4	2.2	6.9	1.5	-0.1	2.6	1.1	2.2	1.6	0.6	1.3	0.6
Arm fat mass (left)	0.3	1.2	3.1	0.9	-0.9	1.0	1.8	0.6	1.2	-1.1	0.8	1.2
Number of self-reported non-cancer illnesses	0.5	0.8	2.6	-1.2	-1.3	0.9	0.7	0.3	-0.0	-1.6	-0.4	-0.2
Average weekly champagne plus white wine intake	1.2	1.6	3.4	1.8	1.1	1.7	0.3	1.1	-1.3	1.1	1.1	-1.2
Miserableness	0.8	1.3	4.5	0.6	-0.6	1.0	-0.7	2.1	1.0	1.8	1.0	-0.4
Guilty feelings	2.9	4.4	10.6	1.8	0.7	2.9	-1.2	3.2	0.8	2.7	2.1	-1.7
Wears glasses or contact lenses	1.3	1.5	4.2	-2.0	0.6	-1.1	-0.4	-1.8	-1.4	-0.1	-1.5	0.5
Ever taken oral contraceptive pill	0.4	0.5	2.5	0.8	-0.1	1.6	0.3	0.3	0.6	0.6	-0.3	-0.7
Hearing aid user	1.2	1.4	5.4	-1.0	2.3	0.8	-2.1	0.3	-0.5	0.6	0.3	0.7
Mother’s age at death	0.2	0.3	1.4	1.2	-0.6	-0.2	0.1	-0.7	0.5	-0.2	0.4	0.0
Financial situation satisfaction	1.0	1.2	2.4	-0.8	-0.8	0.7	1.0	-0.8	1.1	-1.5	-1.5	-1.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.0	-0.0	0.8	0.3	-0.5	-0.3	-0.8	0.8	-0.7	-1.0
Commuting to job workplace: Public transport	0.4	0.5	1.1	0.5	-0.6	-0.4	1.1	0.5	0.5	-1.0	0.1	-1.0
Eye problems/disorders: Glaucoma	2.4	2.8	6.1	2.4	0.3	1.8	0.2	2.5	0.2	1.8	2.4	-0.7
Medication: Blood pressure	0.6	1.2	5.9	-2.4	-0.6	0.0	0.2	0.2	-1.0	-1.1	-1.0	-1.0
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.5	0.7	-1.6	-1.8	1.4	-0.5	1.1	-0.6	0.1	1.9
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.0	-0.6	0.2	-0.0	-1.0	0.2	0.9	0.8	-0.4	0.2
High cholesterol (Self-reported)	0.6	1.1	3.9	-0.4	-2.0	1.1	1.4	1.2	-0.2	-0.6	-0.5	0.1
Medication: Bendroflumethiazide	0.1	0.2	0.7	-0.4	-0.2	-0.5	0.1	0.8	-0.3	-0.5	0.1	0.5
Medication: Paracetamol	1.1	1.7	9.9	-1.0	0.3	0.2	-0.7	0.1	1.2	1.4	0.6	3.1
Medication: Lisinopril	1.6	2.1	5.1	-1.8	-1.5	-1.3	1.6	-1.0	-0.6	-1.6	-2.3	-0.7
Medication: Atorvastatin	1.4	1.8	4.4	1.0	-1.2	1.7	1.4	2.1	1.1	0.2	1.5	0.7
Illnesses of father: High blood pressure	0.3	0.4	1.2	-0.5	-0.7	1.1	0.2	-0.6	-0.3	-0.6	-0.3	-0.6
Alcohol drinker status: Never	0.9	1.1	2.5	0.8	0.3	1.6	-1.2	1.2	0.1	1.0	1.5	0.4
Ever smoked	0.6	1.0	1.8	0.8	1.2	1.1	-0.8	1.0	-0.7	1.3	1.3	0.3
Basal metabolic rate	0.3	1.5	5.8	1.0	-0.3	2.4	1.0	1.8	1.2	0.5	0.9	0.2
Leg fat percentage (left)	0.1	0.3	1.0	0.2	-0.1	0.3	0.8	0.5	-0.2	-0.8	0.5	1.0
Arm fat-free mass (left)	0.2	1.1	4.5	0.7	0.2	2.1	0.3	1.6	1.2	0.6	0.6	-0.2
Number of operations (self-reported)	0.6	0.9	5.9	-0.5	-0.2	-0.3	0.5	-0.7	-0.1	-0.2	0.7	2.4
Average weekly beer plus cider intake	1.2	1.7	6.3	-2.5	-1.5	-0.9	0.1	-0.4	0.6	-0.5	-2.1	-1.0
Irritability	0.2	0.3	1.0	-0.4	-0.8	0.3	0.2	0.2	-0.2	-1.0	0.9	0.0
Risk taking	1.5	2.1	3.6	1.9	1.0	1.0	-1.8	0.9	1.9	1.4	1.1	-1.6
Ever had prostate specific antigen (PSA) test	1.2	1.3	6.5	-1.0	0.5	-0.6	-0.4	-2.5	-1.0	-1.7	0.2	0.1
Fractured/broken bones in last 5 years	1.1	1.5	5.4	1.0	-1.0	1.8	0.9	2.3	0.2	0.9	0.8	-0.2
Age started oral contraceptive pill	0.6	0.7	2.2	-1.5	-0.3	-1.3	0.0	-0.9	-1.2	-0.5	-0.4	0.1
Diastolic blood pressure, automated reading	0.9	2.7	7.3	-2.7	-1.7	-1.0	1.7	-0.7	-0.7	-2.2	-2.0	-0.3
Ever depressed for a whole week	0.4	0.4	1.7	-0.2	1.3	0.4	-0.6	0.1	-0.4	0.6	-0.1	-1.1
Unable to work because of sickness or disability	0.8	1.1	2.5	-1.5	0.5	-1.6	-0.6	-0.9	-1.0	-0.5	-1.3	0.6
Commuting to job workplace: Cycle	1.5	1.9	5.6	1.1	-1.4	1.7	1.8	2.4	0.2	0.9	0.4	-0.7
Myopia	0.9	1.3	3.5	-1.9	-1.0	0.3	1.2	-0.1	-1.2	-1.6	-1.0	0.6
Vascular/heart problems diagnosed by doctor	0.5	1.2	6.2	2.5	0.8	0.4	-0.4	0.6	0.7	1.6	0.5	-0.5
Cholesterol lowering medication	1.1	1.6	5.2	-1.2	-0.9	2.0	1.0	2.3	-0.4	0.5	-0.8	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.2	-1.6	-0.3	1.8	-0.3	-0.9	-0.1	-1.4	-0.1	0.3
Pain experienced in last month	0.8	1.4	5.1	0.5	2.3	-0.1	-1.7	0.6	-0.9	0.5	0.9	-1.4
Supplements: Calcium	0.3	0.3	1.4	-0.0	0.7	-0.2	-0.7	-0.1	-1.2	-0.0	0.4	-0.5
Basal cell carcinoma (self-reported)	0.6	0.8	2.8	0.1	0.4	-0.0	0.8	-0.2	-1.1	-1.0	-0.9	-1.7
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.7	-0.2	1.3	0.4	-1.2	0.6	1.2	-0.2	0.5	0.1
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.7	-0.6	-1.6	0.3	0.6	0.9	1.6	0.3	-0.1	-0.6
Heart disease (siblings)	2.9	3.5	12.0	-2.1	-3.5	1.3	1.5	0.4	0.1	-1.7	-2.2	-1.8
Alcohol drinker status: Previous	0.9	1.0	3.2	1.8	-0.3	0.4	1.2	1.5	0.3	0.5	1.3	-0.4
Pack years of smoking	1.2	1.8	5.9	0.1	0.7	-1.8	-0.7	-2.3	0.2	-0.6	0.4	2.4
Impedance of whole body	0.3	1.3	2.2	-1.5	-0.6	-0.7	-0.2	-0.8	-1.3	-1.5	-1.4	-1.5
Leg fat mass (left)	0.2	0.7	1.6	0.8	-0.3	1.3	1.2	1.2	0.6	-0.4	0.8	0.6
Arm predicted mass (left)	0.3	1.3	4.9	0.9	0.5	2.2	-0.1	1.7	1.1	0.9	1.1	-0.2