TWAS hub - FAM170B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0892	0.0336	1.5e-10	0.100	0.103	0.090	NA	0.098	2.4e-11	1.1e-11	2.3e-10	NA	4.4e-11
2	TCGA	Soft Tissue Sarcoma	0.0680	0.0350	8.7e-04	0.089	0.064	0.065	NA	0.071	6.2e-06	1.2e-04	1.1e-04	NA	4.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Platelet Count	13.4	155.2	185.0	-11.2	-13.6
Blood White Count	10.5	77.7	86.7	-8.3	-9.3
Pulse rate	8.4	14.2	15.0	3.7	3.9
Pulse rate, automated reading	7.4	23.8	23.9	4.9	4.9
Serious illness, injury or assault of a close relative in last 2 years	6.9	8.0	8.1	2.8	2.8
Medication for hormone replacement therapy	6.0	6.6	8.8	2.1	3.0
Leg pain on walking	5.2	6.5	7.2	2.7	2.4
Illness, injury, bereavement, stress in last 2 years	4.9	6.0	6.8	-2.6	-2.3
Ever had prostate specific antigen (PSA) test	4.1	4.8	4.8	2.2	2.2
Severe depression (siblings)	3.9	4.3	4.7	-2.2	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	3.9	8.9	10.5	-3.2	-2.7
Age started oral contraceptive pill	3.8	4.7	6.6	-1.7	-2.6
Heel T-Score	3.7	29.7	32.0	-5.2	-5.7
Heel bone mineral density (BMD) T-score, automated (left)	3.7	8.4	9.9	-3.1	-2.6
Maternal smoking around birth	3.5	5.0	6.6	1.8	2.6
Qualifications: None of the above	3.4	7.2	9.8	-2.1	-3.1
Pulse wave reflection index	3.4	4.2	4.5	-2.0	-2.1
Mean Putamen Volume	3.3	3.7	4.5	-1.7	-2.1
Illnesses of father: Heart disease	3.2	4.5	4.8	2.0	2.2
Mouth/teeth dental problems	3.0	4.6	5.1	-2.2	-2.0
Exposure to tobacco smoke outside home	3.0	4.0	4.4	2.1	1.9
Back pain experienced in last month	3.0	4.4	4.8	-2.2	-2.0
Emphysema/chronic bronchitis	2.9	3.2	3.3	-1.8	-1.8
Prostate Cancer	2.7	3.8	3.9	-2.0	-1.9
Neuroticism (2016)	2.7	3.9	5.6	2.4	1.5
Mouth/teeth dental problems: Loose teeth	2.7	3.2	3.4	1.8	1.8
Handedness (chirality/laterality): Left-handed	2.7	3.3	3.8	-1.9	-1.7
Serious illness, injury or assault to yourself	2.6	3.1	3.4	1.7	1.9
Hair/balding pattern: Pattern 4	2.6	6.3	6.9	2.4	2.6
Medication: Atorvastatin	2.6	3.3	4.3	-1.5	-2.1
Mouth/teeth dental problems: Mouth ulcers	2.5	4.0	5.2	1.6	2.3
Medication: Lisinopril	2.5	3.2	3.9	-1.6	-2.0
Body Mass Index (BMI) (2010)	2.3	3.2	3.4	-1.7	-1.8
Systolic Blood Pressure	2.3	11.5	12.1	-3.3	-3.5
Smoking status: Previous	2.3	3.4	3.5	-1.9	-1.8
Blood Eosinophil Count	2.2	16.8	18.1	-3.9	-4.3
Qualifications: O levels/GCSEs or equivalent	2.2	3.4	3.7	1.9	1.8
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	3.5	-1.8	-1.9
Type 2 Diabetes (T2D) (2012)	2.0	2.3	2.9	1.7	1.3
Migraine (self-reported)	2.0	2.5	2.8	1.7	1.5
HbA1C	1.9	2.2	2.7	-1.3	-1.6
Waist Hip Ratio (WHR)	1.9	8.5	10.1	-2.6	-3.2
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	2.5	1.6	1.2
Crohns Disease (2017)	1.8	4.0	5.2	1.7	2.3
Had menopause	1.8	2.2	2.9	-1.2	-1.7
Qualifications: A levels/AS levels or equivalent	1.8	4.0	5.5	2.3	1.6
Chronic bronchitis/emphysema (father)	1.7	1.9	2.4	-1.6	-1.2
Diabetes diagnosed by doctor	1.7	2.8	2.8	-1.7	-1.6
Medication: Lansoprazole	1.6	1.8	2.5	-1.6	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	2.5	-1.1	-1.6
Commuting to job workplace: Car/motor vehicle	1.6	1.8	2.2	1.5	1.2
Medication: Gliclazide	1.6	1.8	2.5	-1.0	-1.6
Diastolic blood pressure, automated reading	1.6	5.0	6.7	-1.8	-2.6
Smoking Status	1.5	3.5	4.7	-1.5	-2.2
Townsend deprivation index at recruitment	1.5	2.1	2.5	-1.3	-1.6
Past tobacco smoking	1.5	2.8	3.5	1.5	1.9
Knee pain experienced in last month	1.5	2.3	3.2	-1.2	-1.8
Heart disease (siblings)	1.5	1.8	3.1	-1.8	-0.8
Crohns Disease (2012)	1.4	2.2	2.4	1.4	1.6
Type 2 Diabetes (T2D) (2018)	1.4	2.6	3.0	-1.7	-1.5
Comparative height size at age 10	1.4	7.8	8.3	-2.9	-2.7
Loneliness, isolation	1.4	1.9	3.0	1.7	0.9
Ever taken oral contraceptive pill	1.4	1.6	1.7	1.2	1.3
Alcohol drinker status: Previous	1.4	1.6	2.6	-0.7	-1.6
Ever had bowel cancer screening	1.3	1.5	1.9	1.1	1.4
Age at First Birth	1.2	1.8	2.8	0.9	1.7
Ulcerative Colitis	1.2	1.7	1.9	1.4	1.3
Respiratory disease	1.2	2.6	4.6	0.8	2.1
Systolic blood pressure, automated reading	1.2	3.5	4.0	-1.7	-2.0
Taking other prescription medications	1.2	1.9	2.1	1.3	1.4
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	1.5	-1.0	-1.2
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	1.6	-1.3	-1.1
Suffer from ‘nerves’	1.2	1.8	2.0	1.4	1.3
Eye problems/disorders: Cataract	1.2	1.4	2.3	0.7	1.5
Bipolar Disorder (2018)	1.1	1.7	2.4	1.5	1.0
Peak expiratory flow (PEF)	1.1	2.6	3.3	-1.4	-1.8
Shortness of breath walking on level ground	1.1	1.3	1.8	1.4	0.8
Bipolar Disorder (2011)	1.0	0.9	1.0	0.9	1.0
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	1.8	0.9	1.3
Ever had hysterectomy (womb removed)	1.0	1.2	1.9	-0.7	-1.4
Supplements: Glucosamine	1.0	1.4	1.5	-1.1	-1.2
Diabetes (self-reported)	1.0	1.6	1.7	-1.3	-1.2
Wheeze or whistling in the chest in last year	1.0	1.9	3.1	-1.8	-0.8
Medication for pain relief, constipation, heartburn	1.0	1.7	1.8	1.2	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	1.4	1.2	1.0
Eye problems/disorders: Glaucoma	1.0	1.1	1.6	-1.3	-0.8
Pain experienced in last month	1.0	1.6	2.0	1.4	1.1
LDL Cholesterol	0.9	1.4	1.6	-1.1	-1.3
Stomach or abdominal pain in last month	0.9	1.2	1.8	-1.4	-0.7
Heart attack	0.9	1.1	1.3	-1.2	-0.9
Illnesses of siblings	0.9	1.3	1.5	1.2	1.0
Falls in the last year	0.9	1.2	1.3	1.0	1.1
Length of working week for main job	0.9	1.0	1.1	1.1	1.0
Exposure to tobacco smoke at home	0.9	1.0	1.0	1.0	1.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.7	-0.6	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	1.2	-1.1	-0.9
Guilty feelings	0.9	1.4	1.4	1.2	1.2
Myopia	0.9	1.3	2.0	1.4	0.8
Irritable Bowel Disease (IBD)	0.8	1.8	2.6	1.1	1.6
Lung FEV1/FVC ratio	0.8	3.9	4.2	-1.9	-2.0
Waist circumference	0.8	2.8	4.5	-1.0	-2.1
Hearing difficulty/problems with background noise	0.8	1.3	2.4	0.5	1.5
Impedance of arm (right)	0.8	3.6	4.9	-1.6	-2.2
Medication: Paracetamol	0.8	1.3	1.4	-1.2	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	1.7	0.4	1.3
Medication: Aspirin	0.8	1.0	1.7	-1.3	-0.6
Medication: Bendroflumethiazide	0.8	1.2	1.4	1.2	1.0
Cardiovascular Disease	0.7	2.2	3.2	-1.8	-1.1
Trunk fat mass	0.7	3.2	4.8	-1.2	-2.2
Happiness	0.7	0.8	1.4	-0.6	-1.2
Depression (self-reported)	0.7	0.8	1.0	1.0	0.8
Impedance of arm (left)	0.7	3.2	4.2	-1.4	-2.1
Medication: Allopurinol	0.7	1.0	1.8	-0.3	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	2.0	0.9	1.4
Commuting to job workplace: Public transport	0.7	0.8	1.0	1.0	0.8
Rheumatoid Arthritis	0.6	0.9	1.1	1.0	0.8
Trunk fat percentage	0.6	2.5	4.2	-0.9	-2.1
Number of live births	0.6	0.8	1.6	1.3	0.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	2.2	-1.3	-1.5
Asthma	0.6	1.1	2.0	0.5	1.4
Blood clot in the leg (DVT)	0.6	0.7	1.2	-1.1	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	0.7	0.8	0.9
Commuting to job workplace: Walk	0.6	0.7	1.0	-0.6	-1.0
Multivitamins +/- minerals	0.5	0.7	1.1	0.5	1.1
Number of incorrect matches in round	0.5	0.8	1.0	-0.8	-1.0
Had other major operations	0.5	0.6	0.6	-0.8	-0.7
Worrier / anxious feelings	0.5	1.0	1.2	-1.1	-0.9
Mouth/teeth dental problems: Dentures	0.5	0.9	1.3	1.2	0.7
Standing height	0.5	4.5	5.6	-2.4	-1.9
High blood pressure (siblings)	0.5	0.7	1.1	-1.1	-0.5
Body fat percentage	0.5	1.8	3.2	-0.6	-1.8
Number of full brothers	0.5	0.7	1.0	0.6	1.0
Number of children fathered	0.5	0.6	1.1	0.4	1.0
Qualifications: College or University degree	0.5	1.7	2.2	1.0	1.5
Eye problems/disorders: None of the above	0.5	0.5	1.0	1.0	-0.3
Whole body fat mass	0.5	2.0	3.4	-0.8	-1.8
Overall health rating	0.5	1.0	1.2	-1.1	-0.9
Medication: Aspirin	0.5	0.6	1.3	-1.1	-0.1
Mineral and other dietary supplements	0.5	0.6	0.8	0.7	0.9
Asthma (self-reported)	0.5	1.0	1.8	0.4	1.3
Arm fat mass (left)	0.5	1.9	3.0	-0.8	-1.7
Supplements: Calcium	0.5	0.5	0.7	-0.5	-0.9
Bipolar Disorder or Schizophrenia	0.4	1.0	1.4	1.2	0.8
Depression (Nagel 2018)	0.4	0.7	0.8	0.9	0.7
Alzheimer’s Disease (in father)	0.4	0.4	0.6	0.4	0.8
Height	0.4	6.8	8.1	-2.8	-2.4
Relative age voice broke	0.4	0.6	0.7	0.7	0.8
Qualifications: CSEs or equivalent	0.4	0.5	0.7	0.8	0.5
Medication: Atenolol	0.4	0.5	0.5	-0.7	-0.7
Arm fat percentage (right)	0.4	1.7	3.1	-0.6	-1.8
Father’s age at death	0.4	0.5	1.0	0.3	1.0
Medication: Cholesterol lowering	0.4	0.7	0.8	-0.9	-0.8
Lung cancer (father)	0.4	0.4	0.9	-0.9	0.1
Arm fat mass (right)	0.4	1.7	2.8	-0.8	-1.7
Leg fat percentage (right)	0.4	1.6	2.8	-0.6	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	0.9	-0.4	-1.0
Health satisfaction	0.4	0.5	0.9	1.0	0.0
Medication: Omeprazole	0.4	0.4	0.9	0.9	-0.1
Medication: Seretide 50 evohaler	0.4	0.4	0.7	-0.8	-0.4
Heart disease (mother)	0.4	0.5	1.0	0.3	1.0
Leg fat mass (right)	0.4	1.5	2.6	-0.6	-1.6
Illnesses of siblings: Diabetes	0.4	0.5	0.8	-0.5	-0.9
Arm fat percentage (left)	0.4	1.4	2.7	-0.4	-1.6
Average weekly red wine intake	0.4	0.6	0.7	0.8	0.7
Qualifications: nursing, teaching	0.4	0.6	1.3	-0.1	1.1
Illnesses of father: None of the above (group 1)	0.4	0.5	0.7	-0.7	-0.8
Wears glasses or contact lenses	0.4	0.4	0.8	0.9	0.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.9	1.0	-0.1
Medication: Blood pressure	0.4	0.7	0.9	-0.9	-0.7
Leg fat percentage (left)	0.4	1.3	2.4	-0.5	-1.6
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.7	-0.8	-0.6
Leg fat mass (left)	0.4	1.5	2.6	-0.6	-1.6
Coronary Artery Disease (CAD)	0.3	0.3	0.6	-0.2	-0.8
Sensitivity / hurt feelings	0.3	0.6	1.1	1.1	0.2
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.9	0.9	0.3
Diabetes (mother)	0.3	0.4	0.6	0.4	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	0.9	1.0	0.1
Weight	0.3	1.5	2.1	-0.9	-1.4
Time employed in main current job	0.3	0.3	0.6	0.8	0.3
Glaucoma (self-reported)	0.3	0.3	0.6	-0.8	-0.2
Birth weight	0.3	0.7	1.1	0.5	1.1
Neck or shoulder pain in last month	0.3	0.4	0.7	0.4	0.8
Medication: Ibuprofen	0.3	0.4	0.8	0.2	0.9
Alcohol intake frequency.	0.3	0.6	1.0	-0.5	-1.0
Had major operations	0.3	0.4	0.6	-0.4	-0.8
Age at last live birth	0.3	0.4	0.7	0.4	0.8
Family relationship satisfaction	0.3	0.3	0.4	-0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	0.8	0.5	0.9
Friendships satisfaction	0.3	0.4	0.5	0.7	0.5
Number of self-reported non-cancer illnesses	0.3	0.4	0.5	0.7	0.6
Illnesses of father: High blood pressure	0.3	0.4	0.7	0.8	-0.2
Ever depressed for a whole week	0.3	0.4	0.5	-0.7	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.5	0.7	-0.4
Depressed Affect (Nagel 2018)	0.2	0.4	0.6	0.8	0.3
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	0.2	0.7
Major Depression (MDD)	0.2	0.2	0.5	0.1	0.7
Reaction Time	0.2	0.5	0.7	-0.8	-0.5
Hypothyroidism (self reported)	0.2	0.5	0.6	0.7	0.7
Number of treatments/medications taken	0.2	0.3	0.5	-0.7	-0.4
Average weekly spirits intake	0.2	0.2	0.3	-0.3	-0.6
Hearing difficulty/problems: Yes	0.2	0.2	0.3	0.4	0.6
Relative age of first facial hair	0.2	0.4	0.6	-0.5	-0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.5	0.1	0.7
Medication: Metformin	0.2	0.3	0.5	-0.7	-0.3
Diabetes (father)	0.2	0.2	0.3	0.6	0.4
Average weekly fortified wine intake	0.2	0.2	0.2	-0.5	-0.4
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.2	0.4	-0.5
Hayfever, allergic rhinitis or eczema	0.2	0.5	0.5	-0.7	0.7
Sitting height	0.2	1.4	2.1	0.8	1.4
Alcohol usually taken with meals	0.2	0.3	0.4	0.6	0.5
Forced vital capacity (FVC)	0.2	0.9	0.9	-0.9	-0.9
Allergy	0.2	0.5	0.6	0.6	-0.8
Hair/balding pattern: Pattern 3	0.2	0.3	0.3	0.6	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	0.1	0.7
Prospective memory result	0.2	0.3	0.3	-0.5	0.6
Illnesses of mother	0.2	0.3	0.4	0.6	-0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.3	-0.1	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.5	0.7	-0.4
Headache pain in last month	0.2	0.4	0.7	0.0	0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.4	0.5	0.7
Gout (self-reported)	0.2	0.2	0.5	0.1	-0.7
Supplements: Vitamin C	0.2	0.3	0.4	-0.6	-0.4
Hypertension (Self-reported)	0.2	0.4	0.6	-0.5	-0.8
Medication for cholesterol	0.2	0.2	0.5	0.0	-0.7
Smoking status: Current	0.2	0.4	0.8	-0.0	-0.9
Average weekly champagne plus white wine intake	0.2	0.3	0.5	0.7	-0.1
Hearing aid user	0.2	0.2	0.4	0.6	-0.2
Mother’s age at death	0.2	0.3	0.3	-0.6	-0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.3	-0.5	-0.4
Risk taking	0.2	0.4	0.5	0.7	0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	0.6	0.8	0.7
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.5	-0.7	-0.0
Impedance of whole body	0.2	1.0	1.2	-0.8	-1.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	-0.8	-0.2
Neuroticism (Nagel 2018)	0.1	0.2	0.4	0.6	0.0
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	-0.2	0.4
Fasting Glucose	0.1	0.1	0.1	0.4	0.3
Lupus	0.1	0.2	0.4	0.7	-0.1
Primary Biliary Cirrhosis	0.1	0.1	0.1	-0.4	-0.2
Schizophrenia (2014)	0.1	0.3	0.3	0.5	0.5
Allergy or Eczema	0.1	0.4	0.6	-0.4	0.8
Lung FVC	0.1	0.3	0.6	0.8	0.0
Neuroticism	0.1	0.3	0.4	-0.3	-0.7
Hand grip strength (left)	0.1	0.2	0.3	-0.5	0.0
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.2	-0.3	-0.5
Supplements: Zinc	0.1	0.1	0.1	-0.0	-0.3
Medication: Co-codamol	0.1	0.1	0.1	-0.3	0.3
Pack years adult smoking proportion	0.1	0.1	0.1	0.3	0.3
Impedance of leg (right)	0.1	0.4	0.5	-0.7	-0.6
Leg fat-free mass (left)	0.1	0.5	0.9	-0.4	-0.9
Current tobacco smoking	0.1	0.1	0.1	0.3	-0.4
Fed-up feelings	0.1	0.1	0.2	0.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	0.0	-0.5
High blood pressure	0.1	0.3	0.4	-0.5	-0.6
High blood pressure (mother)	0.1	0.1	0.2	0.0	0.4
Body mass index (BMI)	0.1	0.3	0.6	-0.1	-0.8
Leg predicted mass (left)	0.1	0.6	1.0	-0.5	-1.0
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	-0.3	-0.2
Financial difficulties in last 2 years	0.1	0.2	0.3	0.5	-0.3
Pain all over the body in last month	0.1	0.1	0.1	0.3	-0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.3	0.1	0.5
Medication: Ramipril	0.1	0.2	0.2	-0.5	-0.4
Trunk fat-free mass	0.1	0.5	0.7	-0.8	-0.6
Hip circumference	0.1	0.2	0.5	-0.0	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.5	-0.7	-0.3
Trunk predicted mass	0.1	0.7	0.9	-0.9	-0.7
Breastfed as a baby	0.1	0.1	0.2	-0.0	-0.5
Tense / ‘highly strung’	0.1	0.1	0.1	-0.3	-0.4
Loud music exposure frequency	0.1	0.2	0.3	0.2	0.5
Forced vital capacity (FVC), Best measure	0.1	0.3	0.6	-0.8	-0.2
Comparative body size at age 10	0.1	0.2	0.2	0.4	0.4
Age at first live birth	0.1	0.2	0.4	-0.6	0.1
Pulse wave peak to peak time	0.1	0.1	0.2	-0.1	0.5
Angina (self-reported)	0.1	0.1	0.1	-0.4	-0.2
Mean time to correctly identify matches	0.1	0.2	0.3	-0.2	-0.5
Chest pain or discomfort	0.1	0.2	0.2	0.3	0.5
Whole body fat-free mass	0.1	0.4	0.5	-0.6	-0.7
Long-standing illness, disability or infirmity	0.1	0.2	0.4	0.7	0.0
Breast cancer (self-reported)	0.1	0.1	0.3	-0.0	0.5
Whole body water mass	0.1	0.5	0.5	-0.7	-0.7
Miserableness	0.1	0.1	0.3	0.1	-0.5
Financial situation satisfaction	0.1	0.1	0.2	0.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.4	-0.3
High cholesterol (Self-reported)	0.1	0.2	0.2	-0.4	-0.5
Medication: Paracetamol	0.1	0.2	0.2	-0.5	-0.4
Alcohol drinker status: Never	0.1	0.1	0.3	-0.5	-0.1
Ever smoked	0.1	0.2	0.2	0.4	-0.3
Basal metabolic rate	0.1	0.7	0.9	-0.7	-0.9
Arm fat-free mass (left)	0.1	0.7	0.8	-0.8	-0.9
Number of operations (self-reported)	0.1	0.2	0.3	0.5	0.2
Average weekly beer plus cider intake	0.1	0.1	0.1	0.3	0.4
Irritability	0.1	0.2	0.4	0.6	0.2
Fractured/broken bones in last 5 years	0.1	0.1	0.3	0.5	-0.0
Unable to work because of sickness or disability	0.1	0.2	0.3	0.5	-0.3
Commuting to job workplace: Cycle	0.1	0.2	0.3	0.2	-0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	-0.3	-0.1
Arm predicted mass (left)	0.1	0.3	0.4	-0.6	-0.6
Schizophrenia (2018)	0.0	0.1	0.1	0.3	0.2
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	-0.2	0.2
Worry (Nagel 2018)	0.0	0.0	0.1	0.2	-0.0
Ulcerative Colitis (UC)	0.0	0.0	0.1	0.2	0.2
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	-0.4	0.1
Breast Cancer	0.0	0.1	0.2	-0.4	-0.2
Ovarian Cancer	0.0	0.0	0.0	-0.2	0.0
HDL Cholesterol	0.0	0.0	0.1	0.2	-0.2
Triglycerides	0.0	0.1	0.1	-0.4	0.1
Blood Red Count	0.0	0.0	0.0	-0.2	-0.1
BMI	0.0	0.2	0.4	0.1	-0.7
Chronotype (morning person)	0.0	0.1	0.1	-0.3	-0.3
Hair Pigment	0.0	0.1	0.1	0.2	0.4
Tanning	0.0	0.1	0.2	-0.1	-0.4
Angina	0.0	0.0	0.1	-0.2	0.1
Vitamin and mineral supplements	0.0	0.0	0.1	0.3	0.1
Hand grip strength (right)	0.0	0.1	0.2	-0.5	0.0
Age when periods started (menarche)	0.0	0.0	0.1	0.3	-0.1
Medication: Levothyroxine sodium	0.0	0.0	0.0	-0.1	-0.1
Impedance of leg (left)	0.0	0.1	0.1	-0.3	-0.2
Nervous feelings	0.0	0.0	0.0	-0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.0	0.0	0.1
Medication: Simvastatin	0.0	0.0	0.0	-0.2	0.0
Fluid intelligence score	0.0	0.0	0.0	-0.2	-0.1
Neuroticism score	0.0	0.0	0.1	0.1	-0.3
Alcohol intake versus 10 years previously	0.0	0.0	0.1	-0.2	0.1
Noisy workplace	0.0	0.1	0.1	0.1	-0.3
Birth weight of first child	0.0	0.0	0.0	-0.1	-0.2
Mouth/teeth dental problems: Bleeding gums	0.0	0.1	0.1	0.1	-0.3
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	-0.1	0.1
Medication: Amlodipine	0.0	0.1	0.1	0.3	0.1
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	0.0	-0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.1	0.2	0.2
Arm fat-free mass (right)	0.0	0.2	0.2	-0.5	-0.4
Worry too long after embarrassment	0.0	0.0	0.1	0.3	0.1
Medication: Blood pressure	0.0	0.1	0.2	0.4	-0.1
Arm predicted mass (right)	0.0	0.0	0.0	-0.2	-0.2
Number of full sisters	0.0	0.0	0.1	-0.0	-0.3
Leg fat-free mass (right)	0.0	0.3	0.5	-0.2	-0.7
Mood swings	0.0	0.0	0.0	-0.0	0.0
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.0	-0.1
Osteoarthritis (self-reported)	0.0	0.0	0.0	0.1	0.2
Leg predicted mass (right)	0.0	0.2	0.4	-0.2	-0.7
Cholesterol lowering medication	0.0	0.0	0.0	-0.1	0.0
Pack years of smoking	0.0	0.1	0.1	0.3	0.2

Hub : Genes

FAM170B

Models

Trait associations