Best TWAS P=8.6e-08 · Best GWAS P=1.59e-08 conditioned to 0.0676
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | -5.1 | -5.3 | 8.6e-08 | 0.94 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | -5.1 | -5.3 | 1.4e-07 | 0.88 | 0.02 | 0.98 | FALSE |