[Hub]/) : Traits : Heel T-Score : ← →

chr1:199,688,536-202,406,708

Best TWAS P=2.31e-14 · Best GWAS P=3.21e-21 conditioned to 0.279

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DDX59	0.44	0.40	lasso	6	0.42	3.0e-55	6.1	-5.6	2.8e-08	-0.40	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	KIF14	0.14	0.04	bslmm	564	0.07	4.7e-09	6.1	-5.3	1.3e-07	-0.43	0.99	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	KIF21B	0.20	0.09	bslmm	667	0.11	4.2e-13	-3.8	-6.0	2.1e-09	-0.15	1.00	0.00	TRUE
4	GTEx	Adipose Subcutaneous	DDX59	0.33	0.18	lasso	3	0.16	3.5e-13	6.1	-6.3	3.9e-10	-0.44	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	CAMSAP2	0.12	0.09	enet	18	0.04	3.8e-04	-4.7	5.4	6.1e-08	0.41	0.94	0.03	FALSE
6	GTEx	Adipose Visceral Omentum	DDX59	0.23	0.20	lasso	3	0.19	2.4e-10	6.1	-6.3	3.9e-10	-0.43	0.99	0.00	FALSE
7	GTEx	Artery Aorta	DDX59	0.24	0.15	lasso	4	0.15	1.1e-08	6.1	-6.0	2.5e-09	-0.38	0.98	0.00	FALSE
8	GTEx	Artery Tibial	DDX59	0.26	0.06	lasso	5	0.14	2.6e-11	-3.5	-5.1	3.0e-07	-0.31	1.00	0.00	FALSE
9	GTEx	Brain Cerebellum	DDX59	0.25	0.34	lasso	2	0.37	5.7e-12	6.1	-6.0	2.3e-09	-0.41	0.69	0.28	FALSE
10	GTEx	Brain Cortex	DDX59	0.37	0.38	lasso	5	0.35	1.6e-10	6.1	-6.0	1.4e-09	-0.43	0.91	0.03	FALSE
11	GTEx	Brain Frontal Cortex BA9	DDX59	0.26	0.08	enet	11	0.04	2.5e-02	-4.7	-5.2	2.2e-07	-0.46	0.11	0.51	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	DDX59	0.44	0.27	lasso	5	0.26	6.2e-09	6.1	-5.6	1.8e-08	-0.41	0.97	0.00	FALSE
13	GTEx	Cells Transformed fibroblasts	CAMSAP2	0.19	0.00	enet	19	0.03	5.1e-03	-2.9	5.9	4.6e-09	0.52	0.02	0.93	FALSE
14	GTEx	Colon Transverse	DDX59	0.35	0.26	lasso	4	0.28	1.6e-13	6.1	-5.6	2.1e-08	-0.39	1.00	0.00	FALSE
15	GTEx	Esophagus Mucosa	DDX59	0.18	0.15	lasso	3	0.14	1.1e-09	6.1	-5.8	8.6e-09	-0.40	1.00	0.00	FALSE
16	GTEx	Heart Atrial Appendage	DDX59	0.40	0.22	lasso	11	0.21	1.0e-09	6.1	-6.0	2.6e-09	-0.38	0.99	0.00	FALSE
17	GTEx	Lung	DDX59	0.20	0.20	enet	17	0.19	1.7e-14	6.1	-5.9	3.7e-09	-0.45	1.00	0.00	FALSE
18	GTEx	Nerve Tibial	DDX59	0.36	0.22	enet	31	0.24	8.2e-17	6.1	-5.2	2.4e-07	-0.34	1.00	0.00	FALSE
19	GTEx	Ovary	DDX59	0.30	0.19	lasso	2	0.07	1.1e-02	5.3	-5.3	1.2e-07	-0.40	0.09	0.09	FALSE
20	GTEx	Pituitary	DDX59	0.34	0.33	lasso	7	0.28	8.0e-08	6.1	-5.9	3.6e-09	-0.42	0.62	0.19	FALSE
21	GTEx	Stomach	DDX59	0.46	0.21	lasso	11	0.18	4.5e-09	6.1	-5.6	1.7e-08	-0.39	0.99	0.00	FALSE
22	GTEx	Thyroid	DDX59	0.40	0.34	lasso	6	0.33	5.8e-26	6.1	-6.0	2.1e-09	-0.42	1.00	0.00	FALSE
23	GTEx	Uterus	DDX59	0.47	0.31	lasso	6	0.31	3.3e-07	6.1	-6.2	4.7e-10	-0.41	0.12	0.16	FALSE
24	METSIM	Adipose	DDX59	0.22	0.20	lasso	9	0.22	3.7e-32	6.1	-5.5	3.2e-08	-0.38	1.00	0.00	TRUE
25	NTR	Blood	DDX59	0.05	0.05	enet	9	0.05	5.2e-15	6.1	-5.4	6.3e-08	-0.42	1.00	0.00	FALSE
26	NTR	Blood	ZNF281	0.02	0.00	bslmm	488	0.00	6.1e-02	2.2	5.8	7.0e-09	0.04	0.05	0.02	TRUE
27	YFS	Blood	DDX59	0.14	0.19	lasso	14	0.19	1.9e-61	6.1	-5.8	4.9e-09	-0.43	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	DDX59	0.20	0.13	lasso	5	0.11	1.0e-06	6.1	-6.2	4.0e-10	-0.43	0.94	0.02	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	DDX59	0.10	0.10	lasso	7	0.09	6.2e-11	6.1	-5.9	3.9e-09	-0.41	1.00	0.00	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	PTPRVP	0.09	0.02	enet	14	0.02	9.9e-04	5.8	5.4	7.2e-08	0.05	0.00	0.93	TRUE
31	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DDX59	0.07	0.05	blup	66	0.04	7.1e-06	5.3	-5.7	1.2e-08	-0.30	0.91	0.00	FALSE
32	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DDX59	0.25	0.23	lasso	4	0.21	4.1e-09	6.1	-6.2	7.8e-10	-0.41	0.99	0.00	FALSE
33	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SHISA4	0.10	0.00	blup	37	0.02	7.0e-02	4.1	-6.2	5.1e-10	-0.06	0.02	0.22	TRUE
34	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DDX59	0.16	0.00	blup	66	0.03	2.6e-02	6.1	-7.6	2.3e-14	-0.61	0.02	0.53	TRUE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDX59	0.17	0.14	lasso	4	0.16	3.6e-16	6.1	-5.3	9.7e-08	-0.35	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Stomach Adenocarcinoma	DDX59	0.12	0.14	lasso	3	0.13	1.2e-09	6.1	-5.9	3.2e-09	-0.42	1.00	0.00	FALSE
37	The Cancer Genome Atlas	Stomach Adenocarcinoma	SHISA4	0.10	0.06	blup	37	0.06	2.5e-05	4.2	-5.4	5.4e-08	-0.06	0.28	0.34	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	DDX59	0.41	0.42	enet	26	0.45	7.0e-48	6.1	-6.6	4.8e-11	-0.42	1.00	0.00	FALSE