Best TWAS P=1.48e-11 · Best GWAS P=3.34e-31 conditioned to 1.48e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Putamen basal ganglia | SERTAD4-AS1 | 0.29 | 0.02 | enet | 17 | 0.21 | 8.6e-06 | 10.1 | -6.0 | 1.7e-09 | -0.44 | 0.08 | 0.16 | TRUE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C1orf133 | 0.13 | 0.00 | blup | 39 | 0.00 | 2.5e-01 | -6.4 | -6.0 | 2.3e-09 | -0.34 | 0.00 | 0.52 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | C1orf133 | 0.30 | 0.12 | enet | 22 | 0.17 | 2.9e-16 | 7.4 | -5.8 | 6.4e-09 | -0.19 | 0.97 | 0.03 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | HHAT | 0.06 | 0.05 | lasso | 2 | 0.06 | 8.4e-07 | -6.6 | -6.8 | 1.5e-11 | -0.37 | 0.99 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SERTAD4 | 0.14 | 0.12 | lasso | 4 | 0.11 | 7.6e-11 | -6.6 | -6.2 | 4.1e-10 | -0.33 | 1.00 | 0.00 | FALSE |