Hub : Genes

CAMSAP2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1170 0.0390 2.1e-04 0.087 NA 0.039 NA 0.003 1.4e-07 NA 3.8e-04 NA 1.6e-01
2 GTEx Cells Transformed fibroblasts 0.1860 0.0630 1.8e-04 -0.001 NA 0.025 NA 0.016 4.1e-01 NA 5.1e-03 NA 2.2e-02
3 GTEx Esophagus Mucosa 0.1060 0.0400 2.1e-03 0.052 NA 0.051 NA 0.055 2.1e-04 NA 2.6e-04 NA 1.5e-04
4 GTEx Esophagus Muscularis 0.1120 0.0460 5.6e-03 0.044 NA 0.013 NA 0.023 1.2e-03 NA 5.5e-02 NA 1.4e-02
5 GTEx Nerve Tibial 0.0909 0.0302 2.8e-04 0.054 NA 0.047 NA 0.055 1.1e-04 NA 3.1e-04 NA 9.5e-05
6 GTEx Prostate 0.3060 0.1080 9.0e-03 0.015 NA 0.055 NA 0.059 1.3e-01 NA 1.7e-02 NA 1.4e-02
7 GTEx Skin Sun Exposed Lower leg 0.1600 0.0510 4.1e-05 0.090 NA 0.065 NA 0.078 6.9e-08 NA 4.6e-06 NA 5.0e-07
8 GTEx Testis 0.2130 0.0720 1.9e-03 0.023 NA 0.102 NA 0.117 3.2e-02 NA 2.9e-05 NA 7.6e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.1 2.5 1.4 1.6 0.4 -0.1 0.8 -0.1 1.4 -1.4
Bipolar Disorder or Schizophrenia 0.6 1.5 4.3 1.6 2.1 0.2 -0.3 -0.5 1.0 1.1 -1.6
Depressed Affect (Nagel 2018) 0.1 0.2 0.5 0.3 0.6 -0.6 0.0 -0.3 0.3 -0.2 -0.7
Depression (Nagel 2018) 0.1 0.1 0.2 0.2 0.3 -0.4 0.1 -0.5 -0.2 0.1 -0.3
Intelligence (Savage-Jansen 2018) 0.8 2.5 11.0 1.4 3.3 1.0 0.5 -1.1 -0.1 1.6 -1.4
Neuroticism (Nagel 2018) 0.3 0.6 2.1 1.5 0.8 0.1 0.6 0.1 0.2 1.2 -0.7
Schizophrenia (2018) 0.5 1.0 2.0 0.9 1.4 -0.0 -0.3 -1.3 1.4 0.3 -1.0
Schizophrenia vs Biploar Disorder 2.0 2.7 5.8 -2.2 -1.1 -1.9 -1.5 -1.7 -0.1 -2.4 -0.6
Worry (Nagel 2018) 0.8 1.8 5.3 2.3 0.8 1.1 1.2 0.5 -0.4 1.8 -1.5
Alzheimer’s Disease (in mother) 0.8 0.9 2.8 -1.7 -0.8 -0.9 -1.2 -0.9 -0.2 -0.9 0.5
Alzheimer’s Disease (in father) 0.1 0.2 0.7 0.2 0.1 -0.4 -0.6 0.1 -0.2 0.1 0.8
Alzheimer’s Disease (including proxy) 1.1 1.6 3.0 -1.6 -1.4 -1.5 -1.7 -1.0 0.1 -1.0 1.0
Crohns Disease (2017) 2.1 4.7 22.4 2.1 4.7 1.0 0.4 1.3 0.2 2.5 -1.4
Irritable Bowel Disease (IBD) 5.3 12.5 42.4 4.1 6.5 2.5 1.7 1.8 0.2 4.5 -2.7
Ulcerative Colitis (UC) 5.2 9.8 28.6 3.8 5.3 2.3 1.7 1.1 0.6 3.9 -3.3
Major Depression (MDD) 0.8 0.9 2.4 -0.7 0.5 -1.0 -1.1 -1.3 0.4 -0.6 -1.6
Reaction Time 0.2 0.3 0.8 -0.4 -0.5 -0.3 -0.4 -0.1 -0.9 0.2 -0.9
Verbal and Numeric Reasoning (VNR) 0.7 1.8 8.3 0.9 2.9 1.1 1.1 -0.1 -0.2 1.3 -1.0
Breast Cancer 0.6 1.4 2.8 0.1 -0.9 1.4 1.5 1.4 0.2 1.0 -1.7
Ovarian Cancer 0.3 0.3 1.4 -0.1 -1.2 -0.2 -0.5 -0.0 -0.3 0.0 0.9
Prostate Cancer 0.5 0.7 2.0 -0.4 -1.4 -0.2 -0.6 -1.1 0.5 -0.2 1.4
Age at First Birth 2.0 2.9 8.4 1.9 2.9 1.7 1.4 1.5 0.5 1.9 0.1
Bipolar Disorder (2011) 7.2 6.9 11.7 3.2 3.4 3.0 2.4 2.5 1.0 3.4 -0.4
Body Mass Index (BMI) (2010) 1.7 2.4 4.6 2.1 1.8 1.3 1.2 2.0 0.6 1.9 -0.5
Coronary Artery Disease (CAD) 3.7 4.4 9.2 2.9 1.0 2.6 2.5 1.9 0.3 3.0 -0.7
Crohns Disease (2012) 1.7 2.7 13.3 1.2 3.6 0.9 0.6 0.7 0.5 1.6 -1.6
Mean Putamen Volume 0.7 0.8 1.7 -0.5 -0.8 -1.3 -1.1 -0.7 0.4 -1.3 -0.3
Fasting Glucose 0.3 0.4 1.0 1.0 0.5 0.6 0.2 0.5 0.1 0.9 0.4
HbA1C 1.3 1.4 3.0 -0.8 1.2 -1.4 -1.6 -1.7 0.5 -1.2 -0.4
HDL Cholesterol 0.2 0.3 1.2 -1.1 -0.7 -0.0 0.0 -0.2 0.2 -0.6 0.1
LDL Cholesterol 0.6 1.0 2.8 1.1 1.6 0.3 0.1 1.7 0.1 0.8 -0.6
Lupus 0.1 0.1 0.3 -0.3 -0.1 0.0 -0.0 0.5 0.5 -0.4 0.2
Neuroticism (2016) 0.5 0.7 1.9 -0.6 0.6 -1.0 -0.5 -1.4 0.8 -0.9 -0.5
Primary Biliary Cirrhosis 0.1 0.2 0.5 0.3 0.5 -0.2 -0.1 -0.5 -0.4 0.5 -0.7
Rheumatoid Arthritis 1.7 2.3 7.5 0.9 -2.7 1.5 1.6 1.0 -0.7 0.7 -2.0
Schizophrenia (2014) 0.5 1.1 3.1 0.5 0.6 -0.5 -0.7 -1.5 1.8 0.2 -1.4
Triglycerides 0.1 0.2 0.7 -0.3 0.4 -0.7 -0.9 -0.0 -0.5 -0.2 -0.2
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.7 -0.8 0.3 -0.3 -0.8 -1.0 -1.1 -1.3 0.1
Ulcerative Colitis 4.2 6.1 21.6 3.0 4.7 1.6 1.0 0.0 1.0 2.8 -2.5
Blood Eosinophil Count 1.7 12.9 26.2 3.9 5.1 3.5 3.5 3.5 -0.9 3.9 -3.0
Blood Platelet Count 0.1 1.3 2.5 1.5 0.9 1.0 1.6 0.2 -1.2 0.9 -1.2
Blood Red Count 1.3 13.0 19.6 -3.9 -3.2 -3.9 -3.8 -3.3 1.9 -4.4 3.8
Blood White Count 0.3 2.3 5.7 2.1 -2.4 1.5 1.6 0.9 -0.1 1.1 1.4
Heel T-Score 2.3 18.0 34.3 5.4 5.9 4.8 5.1 2.6 -1.0 4.1 -2.4
BMI 0.1 0.7 2.5 0.6 -1.6 -0.1 0.2 0.6 0.9 0.4 1.2
Height 0.4 7.1 14.6 -3.8 -1.3 -3.1 -3.1 -2.2 -0.7 -3.5 1.8
Waist Hip Ratio (WHR) 0.3 1.5 3.0 -1.1 -0.9 -1.6 -1.4 -0.5 -0.8 -1.4 1.7
Systolic Blood Pressure 0.1 0.4 2.1 0.5 0.1 -0.0 0.2 -0.1 -0.8 -0.1 -1.4
Smoking Status 0.2 0.5 2.4 0.6 0.4 0.5 0.4 1.5 0.6 0.4 -0.2
Allergy or Eczema 0.2 0.5 1.3 0.2 1.0 0.6 1.0 0.4 -0.4 0.0 -1.1
Cardiovascular Disease 0.1 0.5 1.3 0.8 0.4 0.3 1.2 0.5 1.0 0.3 -0.5
Hypothyroidism (self reported) 4.8 11.1 14.7 3.8 3.3 3.7 3.8 3.1 1.3 3.7 -3.1
Respiratory disease 0.4 0.9 2.2 -1.5 -1.1 -0.2 -0.1 0.2 0.0 -1.3 1.5
Type 2 Diabetes (T2D) (2018) 1.1 2.1 3.5 1.4 1.7 1.4 1.6 1.9 0.8 1.5 -0.7
Lung FEV1/FVC ratio 0.5 2.7 4.8 -1.6 -0.7 -2.1 -2.2 -1.1 -2.1 -2.0 -0.0
Lung FVC 0.3 1.4 5.3 -0.3 2.1 0.8 0.6 0.9 0.2 0.0 2.3
Neuroticism 0.3 0.7 2.1 0.9 1.4 0.4 1.1 0.4 0.5 0.8 -0.4
Chronotype (morning person) 0.2 0.4 1.0 0.9 -0.1 -0.1 -0.5 0.5 -0.7 1.0 0.2
Hair Pigment 0.0 0.9 1.8 1.3 1.0 0.8 0.5 0.9 -0.7 1.3 0.9
Tanning 0.3 3.3 6.4 -2.1 -0.9 -2.2 -2.2 -2.0 0.1 -2.5 0.8
Hand grip strength (left) 0.1 0.3 0.9 -0.6 -0.3 -0.5 -0.5 0.2 0.3 -0.3 0.9
Number of treatments/medications taken 0.8 1.4 3.2 1.2 0.5 1.4 1.5 1.8 1.1 1.1 0.1
Average weekly spirits intake 0.6 0.7 3.3 -0.8 -1.8 -0.6 -0.1 -0.7 1.0 -0.5 0.3
Sensitivity / hurt feelings 0.1 0.2 0.4 -0.5 0.6 -0.6 -0.3 -0.2 -0.1 -0.0 -0.3
Frequency of depressed mood in last 2 weeks 0.4 0.5 2.8 0.3 1.7 -0.5 -0.1 0.4 -0.8 0.4 0.3
Hearing difficulty/problems: Yes 0.9 1.4 3.9 1.0 2.0 1.1 1.0 0.1 0.4 0.7 -1.8
Relative age of first facial hair 0.9 1.8 7.4 0.8 2.7 1.5 1.7 0.6 0.2 0.9 -0.2
Other serious medical condition/disability diagnosed by doctor 2.4 3.2 7.1 2.1 2.7 1.5 1.3 1.9 -0.3 2.3 -0.8
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.2 0.2 -0.5 -0.7 -0.7 1.1 -0.8 0.1 -0.8
Ever had hysterectomy (womb removed) 0.2 0.2 0.8 0.5 0.5 -0.1 0.6 0.3 -0.9 0.1 0.1
Systolic blood pressure, automated reading 0.1 0.4 1.2 0.9 0.2 0.2 0.2 1.1 0.3 0.5 -0.9
Eye problems/disorders: Diabetes related eye disease 1.5 1.7 3.3 1.6 1.2 1.3 1.1 1.4 1.0 1.8 -0.7
Angina 0.3 0.4 1.1 0.6 0.7 -0.4 -0.1 0.9 0.7 0.1 -1.0
Medication for hormone replacement therapy 0.3 0.3 2.5 0.2 -1.6 -0.0 0.3 0.0 -0.0 0.2 -0.2
Vitamin and mineral supplements 1.0 1.4 2.7 -1.0 0.6 -1.6 -1.4 -1.3 -1.0 -1.1 -1.0
Supplements: Zinc 0.5 0.5 2.9 0.0 -0.8 0.3 0.1 0.7 -0.4 0.1 1.7
Medication: Co-codamol 1.5 1.7 2.9 -1.7 -0.8 -1.4 -1.6 -1.4 1.1 -1.2 1.0
Medication: Metformin 0.4 0.6 2.0 1.1 0.1 0.1 0.5 0.7 1.4 0.9 0.4
Diabetes (father) 1.4 1.8 4.1 1.9 0.6 1.5 1.4 0.2 -1.1 2.0 -0.9
Diabetes (mother) 1.0 1.3 2.8 1.0 0.5 1.6 1.7 1.4 -0.3 1.3 0.0
Severe depression (siblings) 4.1 4.6 11.4 2.4 3.4 1.4 0.9 2.1 -0.8 2.4 -2.4
Pack years adult smoking proportion 1.3 1.9 4.4 0.6 -1.6 1.1 1.2 2.1 1.9 1.4 -0.0
Impedance of leg (right) 0.1 0.6 2.8 0.6 1.7 0.5 0.5 -0.5 0.1 -0.3 -0.7
Leg fat-free mass (left) 0.3 1.4 2.6 -1.2 -1.6 -1.6 -1.6 -0.5 -0.4 -0.6 1.0
Trunk fat percentage 0.4 1.5 6.0 -0.1 -2.4 -1.5 -1.5 -0.6 0.2 -0.6 0.9
Hand grip strength (right) 0.2 0.5 1.7 0.0 0.8 -0.1 0.1 0.7 1.3 -0.1 0.8
Townsend deprivation index at recruitment 2.2 3.1 12.7 -0.1 -2.3 0.9 0.9 3.6 -0.9 1.3 1.7
Current tobacco smoking 2.0 3.2 9.1 1.5 0.5 2.2 2.0 3.0 0.8 2.2 -0.2
Average weekly fortified wine intake 0.9 1.1 3.8 0.8 1.9 0.3 0.3 0.2 -1.7 1.0 0.1
Maternal smoking around birth 0.2 0.3 0.6 -0.6 -0.4 -0.6 -0.6 -0.3 0.2 -0.8 0.3
Fed-up feelings 0.2 0.3 1.0 0.3 0.8 -0.1 0.5 0.0 -0.4 0.1 -1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.2 0.4 -0.5 0.3 -0.7 -0.1 -0.1 -0.2 -0.2 0.6
Relative age voice broke 1.2 1.9 3.8 1.2 2.0 1.5 1.6 1.7 -0.6 1.3 -0.6
Taking other prescription medications 1.2 1.9 5.3 1.1 1.7 1.1 1.1 2.3 1.1 1.1 -0.2
Age when periods started (menarche) 0.2 0.5 1.3 0.2 -0.6 0.8 0.6 0.4 -1.1 0.2 1.1
Bilateral oophorectomy (both ovaries removed) 1.1 1.3 6.8 -0.4 -0.3 -0.6 0.1 0.7 -2.6 -0.1 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 2.9 6.6 11.4 2.8 3.4 2.6 2.9 2.1 -1.1 2.3 -2.8
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.4 0.4 0.0 0.6 0.6 -0.1 -0.6 0.6 -0.3
Qualifications: CSEs or equivalent 1.5 1.9 3.2 1.1 -1.1 1.6 1.8 1.6 -1.5 1.6 0.2
Serious illness, injury or assault to yourself 0.5 0.6 1.5 1.1 0.4 0.7 0.6 0.5 0.7 1.2 0.4
High blood pressure 0.1 0.3 1.4 0.6 -0.3 -0.6 -0.2 -0.1 1.2 -0.2 -0.5
Hayfever, allergic rhinitis or eczema 0.2 0.5 1.3 -0.4 1.1 -0.0 0.5 -0.4 -1.2 -0.6 -0.7
Multivitamins +/- minerals 1.0 1.3 2.5 1.1 -1.0 1.5 1.6 1.0 1.0 1.1 0.5
Stomach or abdominal pain in last month 3.4 4.2 15.0 2.0 3.9 1.6 1.6 2.1 -1.5 1.7 -0.5
Supplements: Glucosamine 0.1 0.1 0.2 -0.0 -0.1 -0.2 0.1 -0.5 0.4 -0.3 -0.2
Diverticular disease/diverticulitis (self-reported) 4.2 5.0 10.3 -2.8 -0.6 -3.2 -2.7 -1.8 0.7 -3.2 0.6
Medication: Atenolol 0.2 0.3 0.8 0.7 0.3 -0.1 -0.3 -0.3 0.5 0.6 0.9
Medication: Levothyroxine sodium 3.4 5.8 9.0 2.7 2.8 2.7 3.0 2.4 0.1 2.9 -1.2
Sitting height 0.4 2.5 6.9 0.9 2.6 1.4 1.8 0.2 -1.5 0.9 -2.0
Chronic bronchitis/emphysema (father) 1.2 1.4 3.4 -1.9 -1.4 -1.1 -1.1 -0.5 0.0 -1.2 1.2
High blood pressure (mother) 0.1 0.2 1.0 0.5 0.2 0.2 1.0 -0.1 -0.5 0.2 -0.2
Body mass index (BMI) 0.3 1.1 5.4 0.0 -2.3 -1.2 -1.1 0.1 0.6 -0.1 0.5
Impedance of leg (left) 0.1 0.5 1.8 0.9 1.3 0.4 0.5 -0.7 -0.5 -0.0 -0.5
Leg predicted mass (left) 0.2 1.3 2.4 -1.2 -1.5 -1.6 -1.5 -0.5 -0.4 -0.6 1.0
Trunk fat mass 0.5 2.1 7.5 -0.6 -2.7 -1.8 -1.7 -0.9 0.0 -0.9 1.1
Waist circumference 0.3 1.0 5.5 0.1 -2.4 -0.9 -0.8 -0.1 0.1 -0.0 0.9
Number of incorrect matches in round 0.1 0.2 1.0 0.6 -0.0 -0.6 -1.0 0.1 -0.1 -0.1 -0.4
Past tobacco smoking 0.5 0.9 1.7 0.4 -1.3 1.2 1.3 0.6 -0.7 1.2 0.4
Alcohol usually taken with meals 1.1 1.8 4.5 -0.3 1.1 -1.5 -1.9 -2.1 -1.3 -1.1 -0.4
Nervous feelings 2.0 3.8 7.4 2.1 1.8 1.6 2.0 1.8 -0.8 2.1 -2.7
Frequency of tenseness / restlessness in last 2 weeks 1.9 3.0 6.8 2.1 2.6 0.7 1.1 1.8 -0.8 1.9 -1.8
Hearing difficulty/problems with background noise 0.4 0.6 2.3 0.4 1.3 0.1 0.2 -0.4 0.7 0.4 -1.5
Hair/balding pattern: Pattern 2 0.5 0.6 1.7 -0.6 -0.5 -1.0 -0.8 -0.1 -0.5 -0.7 -1.3
Had menopause 0.9 1.1 2.9 0.6 -1.4 0.3 0.0 1.2 1.7 0.7 1.4
Had other major operations 0.6 0.7 2.9 0.5 0.1 0.5 0.7 -0.1 1.4 0.0 -1.7
Forced vital capacity (FVC) 0.3 1.0 2.0 0.2 1.4 1.2 1.0 1.0 -1.2 0.9 0.3
Heel bone mineral density (BMD) T-score, automated (right) 2.6 6.0 9.0 3.0 2.9 2.8 3.0 1.8 -1.0 2.6 -1.6
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 5.1 0.7 2.2 -0.3 -0.2 0.7 0.7 0.7 -0.1
Qualifications: None of the above 0.8 1.6 7.5 -0.4 -2.7 -0.4 -0.5 1.4 -1.2 -0.6 1.0
Financial difficulties in last 2 years 0.5 0.7 2.2 -1.1 -1.5 -0.6 -0.7 -0.3 0.8 -0.5 0.0
Mouth/teeth dental problems 1.0 1.5 4.1 1.2 1.2 1.5 1.4 -0.3 2.0 1.1 0.0
Heart attack 2.1 2.6 4.4 1.5 2.1 1.5 1.7 2.1 0.2 1.4 -1.6
Allergy 0.1 0.3 1.0 0.8 0.3 0.2 -0.1 0.6 0.0 1.0 0.3
Pain all over the body in last month 0.8 0.8 3.0 -0.7 -1.7 -0.9 -0.8 -0.5 -0.2 -0.4 1.2
Diabetes (self-reported) 1.6 2.5 4.3 1.9 1.2 1.6 1.8 2.1 0.1 2.1 -0.6
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.3 0.3 1.8 0.7 1.1 -0.1 -1.8 0.3 -1.5
Medication: Ramipril 1.0 1.2 3.6 1.1 0.2 0.7 0.7 1.9 1.4 1.1 0.9
Medication: Simvastatin 0.3 0.5 2.1 0.8 -0.1 0.2 0.6 -0.0 1.4 0.4 0.6
Fluid intelligence score 1.2 2.4 10.1 0.8 3.2 1.2 1.1 -1.1 0.0 0.9 -2.0
Illnesses of siblings 1.0 1.4 2.9 -1.7 -0.7 -1.0 -1.4 -0.8 -0.2 -1.5 1.5
Neuroticism score 0.4 0.8 2.2 0.5 1.4 -0.1 0.5 -0.0 -1.5 0.7 -1.0
Weight 0.5 2.3 7.1 -1.1 -2.7 -2.0 -1.9 -0.7 0.1 -1.0 1.0
Impedance of arm (right) 0.1 0.7 1.3 -0.5 1.0 -0.9 -1.1 -0.9 -0.3 -0.9 0.5
Arm fat percentage (right) 0.4 1.6 5.2 -0.1 -2.3 -1.7 -1.7 -0.3 0.3 -0.4 1.1
Trunk fat-free mass 0.4 2.4 4.6 -2.1 -1.8 -1.9 -1.7 -1.1 -0.6 -1.4 1.1
Hip circumference 0.2 0.7 2.9 0.6 -1.7 -0.1 -0.1 0.5 1.1 0.7 0.2
Time employed in main current job 1.0 1.1 5.2 -1.3 -2.3 -0.2 -0.3 0.7 0.2 -0.5 1.1
Alcohol intake versus 10 years previously 0.4 0.6 1.4 0.8 0.4 0.5 0.6 0.7 0.5 1.0 -1.2
Father’s age at death 0.8 1.1 3.5 -0.3 -0.5 -0.7 -1.4 -1.2 0.7 -0.4 1.9
Worrier / anxious feelings 0.5 1.0 3.5 0.1 1.3 -0.5 -0.3 -1.2 -1.9 -0.4 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 1.1 0.0 0.4 -1.0 -0.8 -0.1 0.5 -0.2 0.9
Falls in the last year 0.5 0.6 4.1 0.1 -0.7 -0.3 -0.1 0.4 0.2 0.2 2.0
Hair/balding pattern: Pattern 3 0.1 0.2 0.6 -0.1 0.2 -0.3 -0.3 -0.6 -0.8 -0.1 -0.4
Number of live births 1.9 2.6 11.1 -1.6 -0.7 -1.3 -1.4 -0.2 1.5 -1.0 3.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 1.2 0.2 1.1 0.8 0.7 0.7 -1.1 0.7 0.6
Pulse rate 1.1 1.8 3.6 1.4 1.1 1.5 1.8 0.8 -0.5 1.1 -1.9
Happiness 0.8 1.0 4.3 0.3 0.1 0.3 0.6 1.6 0.2 0.7 2.1
Noisy workplace 0.2 0.2 0.9 0.2 -0.9 -0.1 -0.1 0.8 -0.5 -0.1 0.0
Qualifications: A levels/AS levels or equivalent 0.6 1.4 9.6 0.2 3.1 0.3 0.3 -1.0 0.1 0.2 0.6
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.2 0.6 -0.6 -0.1 0.3 0.0 0.1 -0.8 -0.1 0.4
Mouth/teeth dental problems: Dentures 0.9 1.5 4.7 -1.5 -2.2 -1.1 -1.0 -0.3 0.2 -1.4 0.6
Asthma 0.6 1.1 3.2 -1.0 -1.8 0.5 0.7 0.4 -1.0 -0.7 1.5
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.3 2.7 -1.2 0.2 -1.4 -1.2 -1.6 1.1 -1.4 -0.1
Medication: Cholesterol lowering 1.7 2.7 5.3 1.9 0.1 1.7 1.8 2.3 1.8 1.6 0.5
Depression (self-reported) 0.8 0.9 1.9 0.8 0.8 0.8 1.0 1.0 1.4 0.8 -1.0
Medication: Lansoprazole 0.1 0.1 0.2 -0.2 -0.0 0.2 0.3 0.4 -0.3 0.2 -0.1
Prospective memory result 1.5 1.8 4.4 1.6 0.3 1.6 1.1 2.1 0.1 1.9 0.3
Lung cancer (father) 1.1 1.2 3.5 -1.0 -1.1 -1.1 -1.2 0.3 1.0 -0.7 1.9
Illnesses of mother 1.4 1.8 5.5 -0.1 -1.1 -1.1 -2.0 -0.6 2.3 -0.3 1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 2.9 0.2 1.7 0.4 0.3 0.9 -1.5 0.6 0.5
Pulse wave Arterial Stiffness index 0.4 0.4 1.4 0.0 -0.6 -0.5 -0.3 0.5 1.0 -0.2 1.2
Impedance of arm (left) 0.1 0.6 2.9 -0.1 1.7 -0.3 -0.6 -0.8 0.2 -0.6 -0.2
Arm fat mass (right) 0.5 2.0 6.3 -0.5 -2.5 -1.9 -1.9 -0.6 0.2 -0.5 1.2
Trunk predicted mass 0.4 2.3 4.3 -2.1 -1.8 -1.8 -1.7 -1.1 -0.5 -1.4 1.2
Standing height 0.4 4.2 8.4 -2.9 -1.0 -2.3 -2.2 -2.3 -0.7 -2.4 1.6
Length of working week for main job 2.6 2.9 4.8 2.1 0.5 1.6 1.8 2.1 -1.4 2.2 -1.3
Exposure to tobacco smoke at home 0.9 1.0 2.0 -0.9 1.0 -1.4 -1.3 -0.0 -0.7 -1.2 -0.7
Breastfed as a baby 1.7 2.1 10.4 0.6 3.2 0.5 0.2 0.6 -1.7 0.3 -1.4
Tense / ‘highly strung’ 0.9 1.6 4.4 2.1 0.9 1.1 1.3 0.7 -0.7 1.5 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 3.2 1.4 1.8 1.4 1.4 1.2 0.6 1.6 0.4
Hair/balding pattern: Pattern 4 0.5 1.3 4.0 0.4 0.3 1.6 2.0 1.2 1.2 0.5 0.6
Birth weight of first child 0.6 1.1 5.1 0.3 1.7 0.4 0.6 0.2 -2.3 0.1 -0.4
Peak expiratory flow (PEF) 1.2 2.7 5.6 1.6 1.5 2.3 2.4 1.4 0.4 1.9 0.3
Pulse wave reflection index 0.7 0.8 2.9 -0.9 -0.9 -0.9 -0.7 0.1 0.0 -0.8 1.7
Ever highly irritable/argumentative for 2 days 2.0 2.4 10.2 1.4 3.2 1.0 1.0 1.7 -0.2 0.9 -1.2
Loud music exposure frequency 1.0 1.0 2.0 1.2 -0.0 1.2 1.4 0.9 -0.4 1.4 0.6
Qualifications: O levels/GCSEs or equivalent 0.8 1.2 5.8 0.8 2.4 0.2 0.1 -0.1 -0.6 0.7 -1.5
Mouth/teeth dental problems: Bleeding gums 1.5 2.0 8.0 -1.0 0.9 -1.6 -1.5 -0.4 -2.8 -0.9 -0.5
Blood clot in the leg (DVT) 1.0 1.3 5.4 0.5 -0.4 -0.1 -0.5 -0.7 2.3 0.5 -2.0
Medication: Paracetamol 0.4 0.6 1.8 -0.4 -1.4 0.5 1.0 0.9 0.9 -0.1 0.6
Headache pain in last month 0.8 1.5 3.2 1.1 1.4 1.4 1.3 0.9 0.5 1.8 -0.6
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 3.2 -1.7 0.5 -1.5 -1.8 -1.6 -1.3 -1.1 0.5
Glaucoma (self-reported) 2.4 2.8 4.9 1.9 1.1 2.0 1.9 2.0 -1.2 2.2 0.1
Gout (self-reported) 1.0 1.4 6.7 0.4 2.6 -0.2 0.1 0.2 2.0 -0.0 -0.2
Hypothyroidism/myxoedema (self-reported) 4.4 8.6 12.2 3.5 2.9 3.0 3.0 3.1 1.6 3.5 -2.2
Medication: Amlodipine 0.2 0.3 0.6 0.8 -0.6 0.4 0.8 0.7 -0.4 0.2 0.5
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.5 -0.5 0.3 -0.9 -1.2 -0.7 0.0 -0.5 0.4
Birth weight 0.2 0.5 1.5 -0.3 -0.5 0.4 0.8 0.8 -1.2 0.1 0.6
Chronic bronchitis/emphysema (mother) 0.2 0.2 0.6 -0.4 -0.7 -0.3 0.0 -0.5 -0.6 -0.8 0.1
High blood pressure (siblings) 0.5 0.7 1.8 1.0 -0.6 0.7 0.8 -0.1 0.6 1.0 -1.3
Forced vital capacity (FVC), Best measure 0.2 0.9 3.6 -0.2 1.9 0.6 0.5 0.8 -1.2 0.4 0.8
Body fat percentage 0.4 1.6 6.3 -0.0 -2.5 -1.6 -1.5 -0.8 0.3 -0.6 0.7
Leg fat percentage (right) 0.3 0.9 5.0 0.4 -2.2 -1.0 -0.9 -0.3 0.6 -0.2 -0.2
Arm fat-free mass (right) 0.1 0.7 2.4 -0.8 -1.5 -0.9 -0.7 -0.5 -0.3 -0.4 0.7
Exposure to tobacco smoke outside home 0.8 1.0 4.2 0.2 0.0 1.2 1.0 2.1 -0.7 1.0 -0.1
Comparative body size at age 10 0.7 1.8 5.9 2.4 1.4 0.2 0.1 1.2 -1.0 2.0 -0.3
Number of full brothers 1.3 1.6 4.4 1.1 -0.5 1.8 2.1 1.5 -0.1 1.2 -0.3
Worry too long after embarrassment 0.6 1.0 2.1 0.9 1.3 0.8 1.0 1.0 -0.6 1.4 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 2.2 -0.3 1.5 0.3 0.5 0.4 -0.5 -0.2 0.6
Wheeze or whistling in the chest in last year 0.2 0.4 2.9 -0.0 0.0 -0.4 0.1 0.5 1.7 -0.4 0.2
Number of children fathered 1.1 1.2 2.5 -1.6 -1.5 -0.7 -0.1 -1.2 0.4 -1.5 1.0
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.7 -0.7 0.1 0.2 0.5 -0.8 -0.4 -0.7 -0.3
Age at first live birth 1.5 2.7 15.2 0.3 3.9 -0.0 -0.3 -1.3 -1.0 0.2 -1.8
Pulse wave peak to peak time 0.4 0.4 1.3 -0.2 0.5 0.4 0.2 -0.6 -1.1 0.0 -1.1
Health satisfaction 0.4 0.5 1.3 -0.6 -0.0 -1.1 -0.5 0.3 0.1 -1.1 1.2
Shortness of breath walking on level ground 1.2 1.4 4.0 1.3 1.8 0.5 0.8 0.9 2.0 1.0 -0.2
Qualifications: College or University degree 0.5 1.6 4.3 1.6 2.1 0.9 1.2 -0.4 1.0 1.4 -0.6
Eye problems/disorders: None of the above 0.5 0.6 1.3 -0.1 -0.7 -0.9 -1.1 -1.0 0.5 -0.0 0.8
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.6 0.9 -0.3 -0.3 -0.1 1.6 0.6 0.7 -0.8
Emphysema/chronic bronchitis 0.5 0.5 1.7 -0.5 -0.7 -0.7 -0.9 0.3 0.8 -0.2 1.3
Medication for pain relief, constipation, heartburn 0.1 0.2 0.6 0.6 0.8 0.3 0.1 -0.0 -0.6 0.6 -0.1
Neck or shoulder pain in last month 2.5 3.5 7.0 1.5 1.0 2.5 2.6 2.3 -0.8 2.0 -1.3
Medication: Blood pressure 0.8 1.4 2.9 1.4 0.2 1.2 1.4 1.1 1.7 0.7 -0.9
Angina (self-reported) 0.2 0.3 0.8 0.3 0.4 -0.5 -0.1 0.9 0.9 -0.1 -0.7
Migraine (self-reported) 0.1 0.1 0.5 -0.1 0.5 -0.0 -0.3 -0.2 -0.7 0.1 -0.0
Medication: Ibuprofen 0.8 1.0 1.8 -0.9 0.9 -1.0 -0.8 -1.4 1.3 -1.1 -0.0
Medication: Allopurinol 0.7 0.9 4.0 -0.3 2.0 -0.3 0.0 -0.2 1.6 -0.5 -0.3
Medication: Omeprazole 0.9 1.1 2.1 0.9 -1.4 0.9 0.8 1.3 1.4 1.0 -0.1
Medication: Seretide 50 evohaler 0.7 0.8 2.4 0.9 0.1 1.0 1.0 0.6 1.5 1.0 -0.0
Mean time to correctly identify matches 0.2 0.3 0.8 -0.9 -0.5 -0.6 -0.8 -0.2 -0.4 -0.3 0.4
Heart disease (mother) 1.6 1.9 4.7 1.3 0.5 1.8 2.2 1.4 -1.1 1.3 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.4 2.8 -0.7 -1.5 -1.0 -1.4 -1.7 -1.3 -0.8 -0.2
Whole body fat mass 0.4 1.6 6.4 -0.4 -2.5 -1.6 -1.5 -0.6 -0.0 -0.6 0.8
Leg fat mass (right) 0.3 1.2 5.4 0.0 -2.3 -1.4 -1.3 -0.5 0.0 -0.3 0.5
Arm predicted mass (right) 0.2 0.9 3.9 -0.9 -2.0 -0.9 -0.8 -0.5 -0.3 -0.4 0.7
Pulse rate, automated reading 0.4 1.2 2.7 0.8 1.1 1.2 1.6 1.0 -0.5 0.5 -1.5
Alcohol intake frequency. 0.4 0.9 2.7 0.5 -0.0 0.6 0.3 1.6 1.5 1.2 0.2
Comparative height size at age 10 0.7 4.0 7.2 -2.2 -2.3 -2.5 -2.7 -1.8 -0.7 -1.7 1.2
Number of full sisters 0.3 0.4 0.7 0.5 -0.3 0.5 0.8 0.5 -0.6 0.7 0.8
Suffer from ‘nerves’ 1.8 2.9 6.9 1.4 2.0 0.9 1.1 1.6 -2.6 1.8 -1.6
Overall health rating 0.2 0.4 2.0 0.7 -0.3 -0.4 -0.1 0.6 1.4 0.1 0.1
Chest pain or discomfort 1.2 1.8 9.4 0.9 1.6 0.5 0.7 -0.0 3.1 0.7 0.4
Had major operations 0.2 0.2 0.8 -0.4 -0.9 -0.2 -0.4 -0.5 -0.0 -0.7 0.1
Age at last live birth 1.3 1.8 6.3 -0.9 2.5 -1.3 -1.3 -1.4 -0.6 -1.2 -0.6
Family relationship satisfaction 0.1 0.2 1.0 -0.2 0.4 0.1 0.2 0.3 0.0 0.2 1.0
Leg pain on walking 1.9 2.3 5.6 2.4 0.4 0.8 0.9 1.9 1.6 2.1 1.0
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.3 -0.2 -1.1 0.3 0.7 0.6 -0.3 0.2 -0.7
Commuting to job workplace: Car/motor vehicle 4.2 4.8 10.4 -3.2 -2.0 -1.9 -1.8 -2.2 -0.4 -3.1 1.5
Illness, injury, bereavement, stress in last 2 years 0.1 0.2 0.4 0.3 -0.1 0.6 0.6 -0.2 0.6 0.2 0.3
Medication: Aspirin 0.1 0.1 0.8 0.0 -0.9 -0.1 0.0 0.1 0.3 -0.1 0.2
Supplements: Vitamin C 0.5 0.5 1.1 0.8 -0.6 0.6 0.1 0.9 1.0 0.8 0.7
Knee pain experienced in last month 0.4 0.7 1.4 -1.2 -0.7 -1.0 -0.7 -0.0 -0.4 -0.6 1.2
Hypertension (Self-reported) 0.1 0.3 1.5 0.9 -0.1 -0.4 0.1 0.1 1.2 0.0 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.8 0.1 0.1 0.5 0.7 -0.1 1.4 0.6 1.3
Illnesses of father: Heart disease 5.3 7.3 14.3 3.4 2.1 3.4 3.8 2.6 0.2 3.0 -0.9
Illnesses of siblings: Diabetes 1.3 1.6 2.9 1.6 -0.2 1.3 1.5 1.0 -0.0 1.7 -1.4
Smoking status: Previous 0.6 0.9 2.0 0.1 0.9 -1.2 -1.4 -1.1 0.6 -1.0 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.5 -0.6 0.7 -0.6 -0.7 -0.9 -0.7 -0.1 -1.2
Whole body fat-free mass 0.3 1.9 3.2 -1.7 -1.8 -1.7 -1.6 -0.8 -0.7 -1.0 1.1
Leg fat-free mass (right) 0.2 1.3 2.7 -1.0 -1.6 -1.6 -1.4 -0.5 -0.7 -0.4 1.1
Arm fat percentage (left) 0.3 1.3 4.3 -0.0 -2.1 -1.5 -1.5 -0.3 0.5 -0.3 0.8
Average weekly red wine intake 0.4 0.5 3.0 0.7 1.7 -0.2 -0.5 -0.6 -0.1 0.3 0.2
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.3 -0.3 -0.8 -0.7 -0.6 -1.1 -0.7 -0.8 0.8
Mood swings 0.6 1.2 2.6 -0.5 0.9 -1.6 -1.2 -1.6 0.3 -1.1 -0.7
Loneliness, isolation 0.4 0.5 1.7 -0.1 1.3 -0.0 0.2 0.9 -1.0 0.6 -0.6
Long-standing illness, disability or infirmity 1.1 1.7 4.4 0.6 2.1 0.8 1.0 1.6 1.8 0.6 -1.0
Ever had bowel cancer screening 0.5 0.6 3.5 0.2 -0.0 -0.2 -0.7 0.3 -1.9 0.0 0.6
Diabetes diagnosed by doctor 0.8 1.4 2.4 1.4 1.2 1.0 1.1 1.5 0.8 1.5 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 2.7 0.9 0.5 1.1 1.2 1.4 1.0 0.9 -1.6
Friendships satisfaction 1.3 1.6 3.5 1.4 1.4 1.6 1.9 0.6 0.5 1.6 -0.4
Qualifications: nursing, teaching 1.4 2.2 5.0 1.3 2.2 1.9 1.9 0.7 -0.3 1.6 -0.4
Commuting to job workplace: Walk 0.4 0.5 1.4 1.2 0.9 0.0 0.1 0.3 -0.6 1.0 -0.1
Eye problems/disorders: Cataract 1.0 1.1 2.8 0.4 1.7 1.1 1.2 0.4 -1.5 0.1 -1.1
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 2.6 -0.3 -1.6 -0.8 -0.5 -0.6 -1.0 -0.7 0.3
Medication for cholesterol 0.7 1.0 2.9 0.5 0.4 1.7 1.1 1.1 0.1 0.9 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.8 -0.2 0.2 -0.9 -0.8 -0.6 -0.7 -0.7 -1.7
Back pain experienced in last month 0.3 0.4 1.6 -0.8 -0.8 0.1 0.1 0.8 1.2 -0.4 0.2
Mineral and other dietary supplements 0.4 0.5 0.9 -0.6 0.9 -0.8 -0.7 -0.8 0.6 -0.5 0.6
Breast cancer (self-reported) 1.4 1.7 4.7 -2.1 -2.2 -0.5 -0.4 -0.1 -0.5 -1.6 1.0
Asthma (self-reported) 0.6 1.1 4.1 -1.3 -2.0 0.4 0.6 0.3 -0.5 -0.9 1.3
Osteoporosis (self-reported) 0.6 0.7 3.1 -1.8 -0.5 -0.5 -0.6 -0.1 0.3 -1.1 0.9
Osteoarthritis (self-reported) 0.3 0.4 1.1 -0.8 -0.4 -0.5 -0.2 -0.3 0.3 -0.7 1.1
Medication: Aspirin 0.1 0.1 0.8 0.2 -0.9 -0.0 0.1 0.0 0.1 -0.1 0.4
Medication: Gliclazide 0.8 1.0 2.7 1.1 0.7 1.2 1.6 0.7 -0.0 1.0 -0.6
Illnesses of father: None of the above (group 1) 3.2 3.9 7.3 -2.5 -1.2 -2.6 -2.7 -1.6 -0.3 -2.5 -0.5
Smoking status: Current 1.4 2.2 7.0 0.9 0.6 1.8 1.6 2.6 0.5 1.7 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.8 0.2 1.3 -0.1 -0.2 -0.1 -1.2 0.2 -0.6
Whole body water mass 0.3 1.8 3.6 -1.7 -1.9 -1.7 -1.6 -0.8 -0.6 -1.0 1.1
Leg predicted mass (right) 0.3 1.5 2.9 -1.1 -1.7 -1.7 -1.6 -0.6 -0.8 -0.5 1.1
Arm fat mass (left) 0.5 1.9 4.9 -0.6 -2.2 -1.9 -1.9 -0.6 0.6 -0.7 1.1
Number of self-reported non-cancer illnesses 1.2 2.2 5.9 1.5 1.2 1.1 1.3 1.6 2.4 0.8 -1.2
Average weekly champagne plus white wine intake 0.4 0.5 1.9 0.1 0.0 -1.4 -1.0 -0.6 -0.1 -0.3 0.6
Miserableness 0.6 1.1 3.0 -0.8 1.7 -1.3 -0.7 -0.3 -1.4 -0.5 -1.0
Guilty feelings 1.6 2.4 5.8 1.1 1.7 1.5 1.5 2.4 0.2 2.1 -0.1
Wears glasses or contact lenses 0.3 0.4 0.7 -0.7 -0.8 -0.4 -0.2 0.6 -0.1 -0.8 0.6
Ever taken oral contraceptive pill 1.3 1.5 3.8 0.2 -0.5 1.3 1.2 2.0 -1.1 0.7 -1.7
Hearing aid user 3.0 3.4 5.8 2.4 1.2 2.0 2.0 2.1 -0.3 2.1 -1.6
Mother’s age at death 0.4 0.5 1.2 0.6 0.0 1.0 0.8 1.1 0.5 0.6 -0.1
Financial situation satisfaction 1.0 1.3 4.0 -1.7 -2.0 -1.0 -0.5 -0.1 0.8 -1.1 0.1
Tinnitus: Yes, now most or all of the time 0.7 0.8 1.6 -0.5 0.7 -1.0 -1.3 -0.7 -1.0 -1.2 -0.2
Commuting to job workplace: Public transport 2.4 2.9 6.8 2.6 2.0 1.3 1.0 0.3 -0.3 2.1 -2.3
Eye problems/disorders: Glaucoma 0.8 0.9 2.1 0.5 1.2 0.6 0.6 1.3 -1.4 0.8 0.6
Medication: Blood pressure 0.7 1.4 3.3 -0.8 0.2 -1.8 -1.5 -1.4 -0.8 -1.1 0.9
Pain type(s) experienced in last month: Hip pain 1.2 1.5 2.7 -1.3 -1.1 -1.5 -1.1 -1.6 1.4 -1.2 -0.3
Supplements: Fish oil (including cod liver oil) 0.5 0.6 4.5 0.3 -2.1 0.3 0.0 0.0 -0.0 -0.1 -0.4
High cholesterol (Self-reported) 0.2 0.3 1.3 0.7 -0.0 0.3 0.6 1.1 0.6 0.1 0.3
Medication: Bendroflumethiazide 1.0 1.5 6.8 -0.8 0.4 -1.2 -1.0 -0.7 -2.6 -1.0 0.3
Medication: Paracetamol 0.2 0.4 0.7 -0.7 -0.9 0.3 0.7 0.8 0.4 -0.4 0.4
Medication: Lisinopril 0.6 0.8 2.1 1.5 0.2 1.1 0.7 0.4 0.5 1.4 -0.3
Medication: Atorvastatin 2.9 3.5 7.3 2.3 1.2 1.6 1.6 2.4 0.2 1.9 -2.7
Illnesses of father: High blood pressure 0.3 0.3 0.7 0.6 0.3 0.7 0.3 0.6 -0.1 0.8 0.9
Alcohol drinker status: Never 0.3 0.4 2.3 -0.4 0.4 0.3 0.2 0.3 0.5 -0.1 -1.5
Ever smoked 0.6 1.1 4.0 -0.4 2.0 -0.8 -0.9 -0.1 1.2 -1.0 -0.7
Basal metabolic rate 0.4 2.0 4.2 -1.6 -2.1 -1.9 -1.7 -0.9 -0.5 -1.0 1.0
Leg fat percentage (left) 0.3 1.1 7.1 0.6 -2.7 -1.0 -0.8 -0.4 0.1 0.0 0.1
Arm fat-free mass (left) 0.2 1.1 4.1 -0.9 -2.0 -1.1 -1.0 -0.3 -0.3 -0.3 1.0
Number of operations (self-reported) 0.4 0.6 2.4 0.7 0.9 -0.4 -0.4 -0.3 -0.7 -0.2 -1.5
Average weekly beer plus cider intake 0.2 0.3 2.0 -0.2 -0.3 0.2 0.3 0.1 1.4 0.1 -0.2
Irritability 0.5 0.8 1.3 1.1 0.9 0.2 0.5 -1.1 -0.7 1.0 -1.1
Risk taking 0.5 0.8 1.8 1.0 0.8 0.7 0.6 0.6 1.4 0.5 -1.2
Ever had prostate specific antigen (PSA) test 0.7 0.8 3.4 -0.5 1.2 0.3 0.5 -0.3 -1.9 -0.4 -0.7
Fractured/broken bones in last 5 years 1.3 1.7 8.1 -0.6 -1.5 -1.0 -1.1 0.5 2.8 -0.4 0.5
Age started oral contraceptive pill 0.7 0.9 2.0 0.7 1.1 0.8 0.8 1.3 1.4 0.3 -0.2
Diastolic blood pressure, automated reading 0.2 0.7 1.9 1.1 0.5 0.7 0.9 1.4 -0.4 0.5 -0.6
Ever depressed for a whole week 0.6 0.8 3.5 0.7 1.9 -0.1 -0.3 -0.4 1.4 0.3 0.1
Unable to work because of sickness or disability 0.8 1.0 2.8 0.1 -0.2 1.2 1.4 1.7 0.9 0.8 0.6
Commuting to job workplace: Cycle 4.0 4.8 10.0 2.2 0.3 3.2 3.2 2.1 -0.1 2.6 -1.6
Myopia 0.2 0.3 0.8 0.7 -0.9 -0.3 -0.5 -0.7 -0.2 0.3 0.7
Vascular/heart problems diagnosed by doctor 0.2 0.5 2.4 -0.6 0.1 0.6 0.2 -0.1 -1.5 0.1 1.1
Cholesterol lowering medication 0.3 0.4 1.4 1.2 0.8 -0.3 0.1 0.1 0.5 0.7 0.5
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 2.2 0.8 -1.0 1.2 1.2 1.5 0.1 1.1 0.5
Pain experienced in last month 0.4 0.6 1.2 -0.5 -0.0 -1.0 -1.1 -1.1 -0.3 -1.0 0.6
Supplements: Calcium 1.2 1.3 2.8 -1.5 -0.9 -1.3 -1.7 -0.8 0.7 -1.3 0.5
Basal cell carcinoma (self-reported) 1.0 1.2 2.6 -1.5 -1.6 -1.2 -0.8 -0.5 0.2 -1.3 1.0
Heart attack/myocardial infarction (self-reported) 2.2 2.8 6.1 1.6 2.5 1.4 1.6 2.1 0.1 1.3 -1.8
Deep venous thrombosis (DVT) (self-reported) 1.1 1.5 6.2 0.8 0.2 0.2 -0.3 -0.6 2.5 0.8 -2.0
Heart disease (siblings) 1.4 1.7 3.9 1.4 1.2 1.2 1.5 2.0 -0.3 1.6 -0.5
Alcohol drinker status: Previous 0.5 0.6 1.7 0.9 0.6 0.4 0.2 1.3 -0.1 1.2 0.0
Pack years of smoking 1.1 1.6 4.7 -0.3 -2.2 0.4 0.5 1.6 2.2 0.6 0.2
Impedance of whole body 0.1 0.6 3.2 0.7 1.8 0.4 0.3 -0.6 -0.2 -0.1 -0.5
Leg fat mass (left) 0.3 1.2 5.8 0.2 -2.4 -1.3 -1.2 -0.4 -0.2 -0.0 0.6
Arm predicted mass (left) 0.2 1.2 3.7 -1.0 -1.9 -1.3 -1.2 -0.4 -0.2 -0.6 1.1