Hub : Genes

DDX59

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.4450 0.0440 0.0e+00 0.403 0.388 0.413 0.411 0.419 1.3e-52 3.8e-50 3.0e-54 6.3e-54 3.0e-55
2 GTEx Adipose Subcutaneous 0.3270 0.0580 1.8e-09 0.179 NA 0.128 NA 0.162 1.5e-14 NA 1.4e-10 NA 3.5e-13
3 GTEx Adipose Visceral Omentum 0.2280 0.0660 3.8e-04 0.197 NA 0.168 NA 0.194 1.8e-10 NA 4.7e-09 NA 2.4e-10
4 GTEx Artery Aorta 0.2430 0.0630 2.8e-04 0.150 NA 0.144 NA 0.151 1.2e-08 NA 2.6e-08 NA 1.1e-08
5 GTEx Artery Tibial 0.2552 0.0529 4.2e-07 0.063 NA 0.126 NA 0.143 1.2e-05 NA 4.6e-10 NA 2.6e-11
6 GTEx Brain Cerebellar Hemisphere 0.3880 0.1160 7.6e-04 0.220 NA 0.236 NA 0.125 2.4e-06 NA 9.4e-07 NA 4.3e-04
7 GTEx Brain Cerebellum 0.2460 0.0940 1.9e-03 0.344 NA 0.339 NA 0.373 5.5e-11 NA 8.2e-11 NA 5.7e-12
8 GTEx Brain Cortex 0.3690 0.1000 2.5e-04 0.375 NA 0.307 NA 0.350 2.7e-11 NA 3.6e-09 NA 1.6e-10
9 GTEx Brain Frontal Cortex BA9 0.2574 0.0841 1.4e-03 0.082 NA 0.045 NA 0.014 3.5e-03 NA 2.4e-02 NA 1.3e-01
10 GTEx Breast Mammary Tissue 0.1780 0.0690 5.5e-03 0.164 NA 0.086 NA 0.151 8.2e-09 NA 3.5e-05 NA 3.6e-08
11 GTEx Breast Mammary Tissue (Female) 0.1917 0.1176 7.0e-02 0.213 NA 0.148 NA 0.180 5.6e-07 NA 3.5e-05 NA 4.7e-06
12 GTEx Cells EBV-transformed lymphocytes 0.4430 0.0860 6.9e-06 0.268 NA 0.248 NA 0.257 2.7e-09 NA 1.2e-08 NA 6.2e-09
13 GTEx Cells Transformed fibroblasts 0.2160 0.0560 9.8e-06 0.035 NA 0.068 NA 0.085 1.1e-03 NA 8.5e-06 NA 6.4e-07
14 GTEx Colon Sigmoid 0.2170 0.0800 5.6e-03 0.021 NA 0.015 NA 0.058 5.9e-02 NA 9.3e-02 NA 4.3e-03
15 GTEx Colon Transverse 0.3480 0.0650 3.1e-07 0.265 NA 0.250 NA 0.276 6.0e-13 NA 3.0e-12 NA 1.6e-13
16 GTEx Esophagus Mucosa 0.1820 0.0500 4.8e-06 0.151 NA 0.119 NA 0.141 2.5e-10 NA 2.4e-08 NA 1.1e-09
17 GTEx Esophagus Muscularis 0.1970 0.0640 1.1e-03 0.048 NA 0.060 NA 0.078 6.4e-04 NA 1.6e-04 NA 1.8e-05
18 GTEx Heart Atrial Appendage 0.4020 0.0820 3.1e-07 0.223 NA 0.146 NA 0.208 2.4e-10 NA 4.3e-07 NA 1.0e-09
19 GTEx Lung 0.1970 0.0443 5.9e-07 0.196 NA 0.190 NA 0.188 6.4e-15 NA 1.7e-14 NA 2.3e-14
20 GTEx Muscle Skeletal 0.0877 0.0339 1.1e-03 0.065 NA 0.050 NA 0.064 5.7e-07 NA 1.2e-05 NA 7.6e-07
21 GTEx Nerve Tibial 0.3636 0.0572 1.1e-10 0.224 NA 0.237 NA 0.236 7.0e-16 NA 8.2e-17 NA 1.1e-16
22 GTEx Ovary 0.2950 0.1070 7.7e-03 0.194 NA 0.016 NA 0.066 1.7e-05 NA 1.3e-01 NA 1.1e-02
23 GTEx Pituitary 0.3360 0.1080 3.1e-04 0.333 NA 0.194 NA 0.283 3.6e-09 NA 1.3e-05 NA 8.0e-08
24 GTEx Stomach 0.4590 0.0790 4.9e-07 0.206 NA 0.153 NA 0.182 3.3e-10 NA 8.8e-08 NA 4.5e-09
25 GTEx Testis 0.1570 0.0650 7.8e-03 -0.001 NA -0.006 NA -0.003 3.7e-01 NA 7.5e-01 NA 4.9e-01
26 GTEx Thyroid 0.4010 0.0530 6.7e-16 0.337 NA 0.330 NA 0.330 1.5e-26 NA 6.5e-26 NA 5.8e-26
27 GTEx Uterus 0.4690 0.1370 6.5e-03 0.309 NA 0.100 NA 0.314 4.3e-07 NA 4.7e-03 NA 3.3e-07
28 METSIM Adipose 0.2234 0.0388 0.0e+00 0.205 0.190 0.212 0.210 0.219 5.7e-30 1.1e-27 4.2e-31 9.8e-31 3.7e-32
29 NTR Blood 0.0464 0.0127 1.6e-08 0.050 0.032 0.047 0.045 0.047 6.4e-16 1.7e-10 5.2e-15 2.4e-14 6.2e-15
30 YFS Blood 0.1442 0.0226 0.0e+00 0.193 0.166 0.193 0.190 0.194 5.3e-61 4.9e-52 4.3e-61 5.0e-60 1.9e-61
31 TCGA Breast Invasive Carcinoma 0.0580 0.0230 2.5e-08 0.027 0.048 0.045 NA 0.046 2.2e-06 3.8e-10 1.4e-09 NA 1.1e-09
32 TCGA Colon Adenocarcinoma 0.2030 0.0780 2.9e-06 0.134 0.084 0.103 NA 0.106 3.9e-08 1.4e-05 1.5e-06 NA 1.1e-06
33 TCGA Kidney Renal Clear Cell Carcinoma 0.0975 0.0357 5.6e-06 0.019 0.062 0.033 NA 0.031 3.1e-03 1.7e-07 1.3e-04 NA 1.9e-04
34 TCGA Kidney Renal Papillary Cell Carcinoma 0.0920 0.0550 9.7e-03 0.006 0.003 0.007 NA 0.012 1.4e-01 1.9e-01 1.2e-01 NA 6.2e-02
35 TCGA Brain Lower Grade Glioma 0.0905 0.0307 5.2e-10 0.103 0.095 0.097 NA 0.103 1.1e-11 6.8e-11 4.5e-11 NA 8.7e-12
36 TCGA Liver Hepatocellular Carcinoma 0.1390 0.0580 1.7e-05 0.127 0.120 0.133 NA 0.118 1.5e-06 2.9e-06 8.0e-07 NA 3.5e-06
37 TCGA Lung Adenocarcinoma 0.0979 0.0346 3.6e-11 0.102 0.083 0.088 NA 0.092 6.2e-12 6.4e-10 1.9e-10 NA 6.2e-11
38 TCGA Lung Squamous Cell Carcinoma 0.0715 0.0299 2.0e-05 0.047 0.045 0.035 NA 0.044 4.4e-06 7.1e-06 6.1e-05 NA 8.0e-06
39 TCGA Ovarian Serous Cystadenocarcinoma 0.1860 0.0620 3.3e-08 0.069 0.087 0.077 NA 0.077 2.1e-05 1.7e-06 6.8e-06 NA 6.7e-06
40 TCGA Pancreatic Adenocarcinoma 0.2460 0.0730 4.0e-09 0.228 0.188 0.205 NA 0.207 5.9e-10 2.4e-08 5.3e-09 NA 4.1e-09
41 TCGA Pheochromocytoma and Paraganglioma 0.1590 0.0870 2.7e-03 0.002 0.028 0.011 NA 0.010 2.7e-01 2.6e-02 1.1e-01 NA 1.2e-01
42 TCGA Prostate Adenocarcinoma 0.1651 0.0469 7.9e-14 0.135 0.148 0.154 NA 0.157 6.3e-14 3.3e-15 7.3e-16 NA 3.6e-16
43 TCGA Stomach Adenocarcinoma 0.1180 0.0420 6.0e-09 0.142 0.106 0.108 NA 0.130 2.0e-10 4.3e-08 3.5e-08 NA 1.2e-09
44 TCGA Thyroid Carcinoma 0.4120 0.0690 0.0e+00 0.421 0.416 0.448 NA 0.446 2.7e-44 1.6e-43 7.0e-48 NA 9.8e-48

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44
Bipolar Disorder (2018) 0.3 0.5 7.0 -0.3 -0.1 0.3 0.7 0.9 -1.0 0.1 -0.2 -1.4 -0.5 -0.6 -0.3 -0.6 0.3 0.6 0.0 0.3 -0.1 0.1 0.0 0.3 0.1 -0.3 -0.0 0.3 -0.1 -0.2 -0.2 -0.5 -0.4 1.6 -0.1 2.6 0.6 1.5 -0.3 -0.2 1.3 1.0 0.2 -0.5 0.2 0.0 -0.3
Bipolar Disorder or Schizophrenia 0.2 0.5 7.1 -0.4 -0.5 -0.1 0.3 0.5 -0.7 -0.1 -0.4 -1.5 -0.2 -0.1 -0.4 -2.1 0.1 0.4 0.3 0.1 -0.4 -0.5 0.2 -0.1 0.1 -0.6 0.1 -0.3 -0.3 -0.2 -0.2 -0.6 -0.6 1.3 -0.4 2.7 0.4 1.0 0.2 -0.4 0.9 1.1 -0.1 -1.0 -0.1 -0.1 -0.4
Depressed Affect (Nagel 2018) 0.4 0.9 5.1 -0.5 -0.3 -0.4 -1.0 -1.7 -0.6 -0.0 -0.1 0.5 -1.4 -1.1 -0.2 -1.0 -1.0 -0.4 -0.6 -1.6 -0.7 -0.7 -1.2 -1.3 -0.2 -0.1 -0.0 0.3 -0.5 0.5 -0.9 0.2 -0.2 -1.1 -0.4 -1.4 -2.3 -2.1 0.4 -0.6 -1.1 -1.6 -0.6 -1.1 -1.3 -0.1 -1.1
Depression (Nagel 2018) 0.8 1.2 3.7 -1.0 -1.0 -1.1 -1.5 -1.7 -0.5 -0.9 -0.9 -0.2 -1.2 -1.1 -0.8 -0.8 -1.0 -1.3 -0.8 -1.5 -1.0 -1.3 -0.1 -1.3 -0.7 -0.8 -0.4 -0.2 -1.0 -0.6 -1.1 -0.4 -0.8 -1.7 -1.0 -1.5 -1.9 -1.9 -0.6 -1.1 -1.0 -1.5 -1.2 -1.0 -1.5 -0.8 -1.3
Intelligence (Savage-Jansen 2018) 0.3 0.8 4.4 -1.0 -1.0 -0.6 -0.3 0.4 -1.2 -1.2 -1.1 -2.1 -0.5 -0.7 -0.8 -1.3 -0.7 -0.4 -0.8 -0.2 -1.1 -0.4 1.0 -0.8 -0.3 -1.0 -0.7 -0.8 -0.7 -1.0 -0.6 -1.3 -1.3 0.7 -0.9 1.6 0.2 0.8 -0.4 -1.0 0.1 0.5 -0.7 -1.1 -0.5 -0.7 -0.8
Neuroticism (Nagel 2018) 0.6 1.4 4.3 -1.0 -0.8 -0.7 -1.1 -1.7 -1.5 -0.5 -0.8 -0.7 -1.6 -1.3 -0.8 -1.2 -1.1 -0.6 -1.1 -1.7 -1.3 -1.0 -0.9 -2.0 -0.8 -0.8 -0.3 0.9 -1.0 -0.1 -1.5 -0.5 -1.0 -0.6 -0.9 -0.5 -2.1 -1.7 -0.1 -1.1 -1.3 -1.6 -1.0 -1.7 -1.5 -0.7 -1.6
Schizophrenia (2018) 0.1 0.3 4.8 -0.3 -0.5 -0.4 -0.2 -0.1 -0.1 -0.2 -0.4 -0.8 0.1 0.3 -0.3 -2.2 -0.1 -0.0 0.4 -0.2 -0.4 -0.7 0.2 -0.5 0.0 -0.5 0.2 -0.5 -0.2 -0.0 -0.1 -0.4 -0.4 0.4 -0.4 1.3 0.0 0.1 0.5 -0.3 0.0 0.7 -0.3 -0.8 -0.3 -0.2 -0.3
Schizophrenia vs Biploar Disorder 0.9 1.2 3.8 1.3 1.2 0.7 0.3 -0.4 1.5 1.3 1.3 1.9 1.1 1.3 1.4 -1.4 -0.0 0.4 1.4 0.4 1.6 0.8 -0.9 0.9 0.6 1.5 1.1 -1.0 1.2 1.0 1.0 1.6 1.5 -0.8 1.2 -1.2 0.0 -0.7 1.3 1.3 0.3 0.8 0.8 1.5 0.7 1.0 1.3
Worry (Nagel 2018) 1.2 2.5 4.6 -1.7 -1.6 -1.4 -1.4 -1.7 -2.0 -1.2 -1.6 -1.7 -1.8 -1.6 -1.5 -1.2 -0.7 -1.1 -1.9 -1.9 -1.8 -1.6 0.4 -1.7 -1.9 -1.6 -0.9 1.7 -1.8 -0.9 -2.2 -1.5 -1.7 -0.7 -1.7 -0.8 -1.7 -1.3 -1.0 -1.8 -1.8 -2.1 -1.6 -2.1 -1.8 -1.6 -2.0
Alzheimer’s Disease (in mother) 1.6 1.9 4.7 1.4 1.4 1.4 1.4 1.5 1.5 1.2 1.3 1.1 1.6 1.5 1.1 1.8 1.0 1.3 1.3 1.7 1.0 0.9 -0.5 1.2 1.6 1.3 1.0 0.1 1.6 0.6 1.6 1.1 1.3 1.2 1.5 1.5 1.6 1.4 1.3 1.4 2.2 1.6 1.4 1.7 1.6 1.4 1.7
Alzheimer’s Disease (in father) 0.2 0.2 1.0 0.3 0.3 0.3 0.5 0.5 0.1 0.3 0.2 0.0 0.4 0.4 0.6 0.8 1.0 0.4 0.1 0.5 0.6 0.2 -0.2 0.8 0.0 0.4 0.4 1.0 0.3 0.3 0.2 0.2 0.2 0.6 0.2 0.2 0.6 0.7 0.5 0.3 0.5 0.4 0.3 0.5 0.5 0.2 0.4
Alzheimer’s Disease (including proxy) 1.0 1.5 3.9 1.1 1.3 1.2 1.3 1.5 1.1 1.2 1.2 1.1 0.8 0.8 1.4 1.6 0.8 1.2 1.3 1.2 1.2 0.6 -0.6 0.8 1.6 1.3 0.7 -0.4 1.4 0.8 1.4 1.1 1.2 0.9 1.3 1.0 1.1 1.4 1.1 1.2 2.0 1.4 1.3 1.9 1.1 1.4 1.4
Crohns Disease (2017) 0.4 0.8 5.7 -0.5 -0.5 -0.1 0.6 1.0 -1.2 -0.2 -0.8 -2.4 0.2 0.1 -0.4 -1.8 0.9 0.2 -0.7 0.7 -0.7 -0.2 0.7 0.4 -0.7 -0.8 0.2 -0.8 -0.5 -0.3 -0.6 -1.1 -1.0 1.5 -0.5 2.1 1.3 1.8 -1.1 -0.5 1.0 0.4 -0.2 -0.9 0.4 -0.6 -0.3
Irritable Bowel Disease (IBD) 2.3 5.4 23.9 -2.5 -2.5 -1.9 -1.0 -0.1 -3.5 -2.2 -2.8 -4.9 -1.3 -1.5 -2.3 -4.0 -1.0 -1.4 -2.8 -0.8 -2.6 -1.9 2.5 -1.4 -2.5 -2.9 -2.0 -2.7 -2.4 -2.2 -2.5 -3.2 -3.1 0.5 -2.5 1.9 0.3 1.3 -3.0 -2.5 -0.1 -0.9 -2.0 -2.9 -1.2 -2.5 -2.3
Ulcerative Colitis (UC) 3.2 5.9 19.8 -2.6 -2.6 -2.1 -1.4 -0.6 -3.6 -2.5 -2.8 -4.5 -1.9 -2.0 -2.4 -4.0 -1.7 -1.8 -3.0 -1.3 -2.6 -2.1 2.7 -1.8 -2.5 -2.9 -2.5 -2.9 -2.6 -2.1 -2.6 -3.2 -3.1 -0.2 -2.6 1.4 -0.5 0.6 -2.8 -2.7 -0.7 -1.3 -2.2 -3.1 -1.7 -2.6 -2.6
Major Depression (MDD) 0.5 0.6 3.0 0.5 0.8 1.0 0.9 0.7 -0.2 0.6 0.8 0.2 -0.3 -0.3 0.9 -0.7 0.3 1.2 0.4 0.2 1.0 0.5 -1.2 0.3 0.8 0.8 1.0 0.4 0.7 1.5 0.5 0.5 0.6 1.0 0.8 1.7 0.1 0.8 0.7 0.6 0.9 1.3 0.8 0.7 0.3 0.9 0.5
Reaction Time 0.0 0.1 0.3 0.1 0.3 0.3 0.4 0.2 -0.1 0.4 0.2 -0.1 -0.2 -0.3 0.2 0.1 0.4 0.5 0.0 -0.1 0.3 0.5 -0.6 0.1 0.2 0.2 -0.0 -0.3 0.3 0.2 0.0 -0.0 0.1 0.1 0.3 0.4 -0.0 0.3 0.2 0.1 0.5 0.1 0.3 0.3 0.0 0.3 0.1
Verbal and Numeric Reasoning (VNR) 0.9 2.2 8.4 -1.6 -1.5 -1.4 -1.4 -0.7 -1.6 -1.9 -1.6 -2.1 -1.4 -1.5 -1.4 -2.9 -1.7 -1.5 -1.3 -1.2 -1.5 -1.6 1.5 -1.8 -0.9 -1.5 -1.4 -2.5 -1.3 -1.6 -1.2 -1.6 -1.6 -0.7 -1.5 1.1 -1.0 -0.5 -1.3 -1.6 -0.7 0.1 -1.5 -1.5 -1.4 -1.3 -1.5
Breast Cancer 0.1 0.3 3.6 -0.2 -0.2 0.1 0.1 0.3 -0.3 -0.3 -0.3 -0.2 0.3 0.3 -0.8 0.9 0.1 -0.4 -0.3 0.3 0.1 0.3 0.7 0.2 -0.5 -0.3 -0.4 1.9 -0.2 -0.8 -0.2 -0.4 -0.4 -0.3 -0.1 1.3 0.6 0.5 0.0 -0.2 -0.3 0.3 -0.1 -0.4 0.2 -0.4 0.4
Ovarian Cancer 1.0 1.4 6.4 0.9 0.9 1.3 1.4 1.6 1.1 1.0 0.9 0.8 0.9 0.9 0.7 1.0 2.0 1.1 0.8 1.4 1.1 1.5 -0.3 1.6 1.0 0.9 1.4 2.5 0.9 0.7 1.1 0.6 0.8 1.3 0.9 0.3 1.5 1.8 0.8 1.0 0.7 0.5 1.2 1.3 1.3 1.0 1.1
Prostate Cancer 0.3 0.5 1.4 0.4 0.7 0.9 0.9 0.9 0.1 0.4 0.7 0.2 -0.2 -0.4 0.7 1.1 0.0 1.1 1.0 0.3 0.7 0.8 -0.7 0.4 0.7 0.7 0.7 -1.0 0.6 1.2 0.5 0.2 0.5 1.2 0.6 0.7 0.4 1.1 0.6 0.5 0.0 0.8 0.8 0.5 0.4 0.8 0.3
Age at First Birth 0.6 0.9 4.7 -0.9 -1.1 -0.6 -0.2 0.4 -1.2 -1.3 -1.1 -2.0 -0.2 -0.3 -1.1 -0.4 -0.2 -0.5 -1.1 0.1 -0.8 -0.6 1.4 -0.6 -0.8 -1.3 -0.7 0.7 -0.9 -1.3 -0.7 -1.3 -1.2 0.6 -1.0 2.2 0.6 0.8 -1.2 -0.9 0.1 0.7 -0.7 -1.4 -0.2 -1.0 -0.7
Bipolar Disorder (2011) 3.6 3.5 12.5 -2.1 -2.2 -1.4 -0.8 0.2 -2.3 -2.2 -2.3 -3.5 -1.5 -1.6 -2.4 -1.3 0.4 -1.2 -2.0 -0.8 -2.0 -1.8 2.4 -1.1 -1.8 -2.4 -1.3 1.3 -2.1 -2.6 -1.9 -2.8 -2.5 0.7 -2.1 3.1 0.3 1.3 -2.0 -2.1 -0.0 -0.1 -1.6 -2.5 -1.2 -2.0 -1.7
Body Mass Index (BMI) (2010) 1.4 1.9 4.6 -1.5 -1.6 -1.4 -1.2 -0.9 -1.8 -1.7 -1.5 -1.9 -1.4 -1.5 -1.4 -0.9 -1.1 -1.1 -1.9 -1.2 -1.7 -1.4 0.9 -1.7 -1.1 -1.5 -1.6 0.1 -1.6 -1.4 -1.5 -1.5 -1.6 -0.3 -1.6 0.9 -1.0 -0.7 -1.0 -1.6 -0.4 -1.0 -1.4 -2.1 -1.4 -1.4 -1.6
Coronary Artery Disease (CAD) 7.2 8.6 12.0 -3.1 -3.3 -3.3 -3.0 -2.7 -3.1 -3.3 -3.4 -3.3 -2.2 -2.1 -3.1 -0.9 -2.6 -2.7 -3.3 -2.6 -3.3 -3.2 2.2 -3.0 -3.3 -3.4 -3.5 0.1 -3.1 -3.0 -3.3 -3.4 -3.4 -2.1 -3.3 -1.9 -2.1 -2.1 -3.0 -3.3 -2.4 -3.3 -3.3 -3.0 -2.9 -3.3 -3.3
Crohns Disease (2012) 0.2 0.3 2.3 -0.3 -0.3 0.0 0.3 0.5 -0.6 -0.0 -0.5 -1.5 -0.0 0.0 -0.3 -1.4 0.6 0.2 -0.3 0.2 -0.8 -0.0 0.2 0.2 -0.3 -0.4 0.4 -0.7 -0.3 -0.1 -0.4 -0.7 -0.7 1.0 -0.3 1.2 0.6 0.9 -0.6 -0.4 0.4 0.2 -0.1 -0.6 0.1 -0.3 -0.4
Mean Putamen Volume 1.4 1.5 3.3 1.5 1.4 1.3 1.1 0.5 1.8 1.6 1.5 1.6 1.4 1.5 1.4 1.0 0.2 1.2 1.5 1.0 0.8 1.5 -1.5 1.2 1.1 1.5 1.4 -0.2 1.4 1.3 1.2 1.7 1.5 0.9 1.4 0.2 0.7 0.2 1.7 1.4 0.7 0.7 1.2 1.0 1.2 1.3 1.1
Fasting Glucose 0.2 0.2 0.8 -0.4 -0.6 -0.5 -0.1 0.2 -0.6 -0.7 -0.6 -0.8 -0.0 -0.1 -0.4 0.0 -0.3 -0.1 -0.9 0.2 -0.3 -0.0 0.7 -0.1 -0.7 -0.6 -0.8 -0.7 -0.5 -0.7 -0.5 -0.8 -0.6 0.5 -0.5 0.1 0.5 0.7 -0.7 -0.4 0.3 -0.2 -0.4 -0.0 0.0 -0.6 -0.2
HbA1C 0.2 0.2 1.4 -0.2 0.2 -0.1 -0.0 0.5 -0.5 0.1 0.2 0.6 -0.9 -1.0 0.8 -1.2 0.1 -0.2 0.2 -0.4 0.6 -0.4 0.4 -0.4 0.6 0.5 -0.1 0.2 0.1 0.8 0.5 0.0 0.2 -0.5 0.0 -0.2 -0.5 0.4 0.8 0.1 0.0 0.2 0.2 0.5 -0.3 0.4 0.0
HDL Cholesterol 0.4 0.7 3.3 1.1 0.7 0.6 0.4 0.1 1.4 0.5 0.7 0.8 1.8 1.8 0.3 0.4 0.7 0.5 1.3 1.1 0.7 0.7 -0.2 0.8 0.4 0.6 1.1 0.2 0.9 0.0 0.9 0.8 0.9 0.4 0.8 -0.4 1.0 -0.1 0.7 1.0 0.3 0.9 0.6 0.8 1.1 0.5 1.0
LDL Cholesterol 0.1 0.2 1.3 0.0 0.1 0.3 0.6 0.7 -0.6 0.2 0.1 -0.7 0.0 -0.1 0.1 -0.5 0.2 0.5 -0.2 0.4 0.1 0.2 -0.5 0.4 -0.1 -0.0 0.1 -0.1 0.0 -0.0 -0.2 -0.2 -0.1 1.1 0.0 0.9 0.6 0.9 -0.0 0.0 0.5 0.1 0.3 -0.3 0.4 0.0 -0.3
Lupus 0.4 0.6 1.6 0.6 0.9 0.9 1.0 0.8 0.4 0.4 0.9 0.7 -0.1 -0.3 0.7 1.0 0.8 1.3 0.3 0.3 0.8 0.8 -0.8 0.5 0.6 0.9 1.1 0.5 0.6 1.3 0.5 0.7 0.8 1.0 0.9 0.4 0.4 0.7 -0.2 0.8 0.8 0.3 1.0 0.7 0.5 0.8 0.8
Neuroticism (2016) 0.2 0.3 2.0 0.3 0.6 0.4 0.0 -0.8 0.2 0.4 0.6 0.7 -0.3 -0.1 0.5 -0.9 -0.1 0.4 0.5 -0.7 0.1 0.3 -1.4 -0.6 0.2 0.6 1.1 0.5 0.3 1.1 -0.1 0.8 0.5 -0.5 0.5 -0.4 -1.1 -1.1 0.7 0.3 -0.5 -0.2 0.2 -0.0 -0.4 0.4 -0.1
Primary Biliary Cirrhosis 0.1 0.1 1.7 0.1 -0.0 -0.1 0.1 -0.1 -0.3 -0.2 -0.1 -0.7 0.3 0.3 0.2 -1.3 0.1 0.3 0.3 0.2 -0.2 0.1 -0.9 -0.3 -0.1 -0.1 0.3 -0.6 -0.0 0.0 -0.2 0.1 -0.1 0.6 0.0 0.3 0.1 -0.1 -0.2 -0.1 0.4 -0.1 -0.0 -0.6 0.1 -0.1 -0.5
Rheumatoid Arthritis 0.8 1.1 3.3 -1.2 -1.2 -0.9 -1.1 -0.6 -1.2 -0.9 -1.1 -0.6 -1.1 -1.1 -1.4 0.8 -0.1 -1.6 -0.9 -0.9 -0.7 -0.8 1.8 -1.2 -0.9 -1.1 -0.9 0.7 -1.2 -1.7 -0.9 -1.1 -1.2 -1.1 -1.2 -1.2 -0.8 -0.5 -1.5 -1.1 -1.2 -0.9 -1.1 -0.4 -1.1 -1.1 -0.9
Schizophrenia (2014) 0.1 0.3 4.8 -0.4 -0.5 -0.4 -0.4 -0.4 -0.4 0.0 -0.4 -1.0 -0.3 -0.0 -0.3 -2.2 -0.6 -0.1 0.4 -0.5 -0.4 -0.5 -0.1 -0.8 -0.0 -0.5 -0.2 -1.2 -0.2 0.1 -0.3 -0.4 -0.5 -0.1 -0.4 0.9 -0.4 -0.2 0.1 -0.4 0.0 0.4 -0.4 -0.8 -0.5 -0.2 -0.5
Triglycerides 0.2 0.4 1.6 0.4 0.6 0.6 0.8 1.0 0.4 0.7 0.6 0.3 0.0 0.1 0.7 0.5 0.1 0.7 0.3 0.6 0.8 0.4 -0.6 0.4 0.7 0.6 0.4 0.6 0.5 0.6 0.6 0.4 0.4 0.9 0.5 1.3 0.6 1.0 0.6 0.5 1.0 0.9 0.7 0.6 0.6 0.7 0.4
Type 2 Diabetes (T2D) (2012) 0.9 1.1 2.7 1.3 0.9 0.9 0.8 0.5 1.1 0.6 1.0 0.8 1.6 1.6 1.0 0.5 1.3 0.7 1.2 1.4 1.3 1.2 -0.6 1.6 0.6 1.1 1.0 -0.7 1.1 0.6 1.1 0.7 1.1 0.8 1.0 0.6 1.2 0.2 1.6 1.2 0.6 1.2 0.9 0.8 1.4 0.8 1.1
Ulcerative Colitis 2.4 3.5 12.2 -2.1 -2.1 -1.7 -1.0 0.3 -2.7 -1.9 -2.3 -3.5 -1.5 -1.6 -1.8 -3.4 -0.9 -1.6 -2.2 -0.7 -1.9 -1.6 2.4 -1.2 -1.4 -2.2 -2.1 -2.1 -1.9 -2.1 -1.6 -2.5 -2.5 -0.0 -2.1 1.6 -0.1 1.1 -2.0 -2.1 0.2 -0.6 -1.6 -2.0 -1.2 -1.8 -1.9
Blood Eosinophil Count 2.2 16.7 23.9 -4.6 -4.5 -4.7 -4.1 -3.2 -3.8 -4.7 -4.6 -4.8 -4.0 -4.2 -4.2 -2.9 -2.6 -4.1 -4.8 -3.9 -4.4 -4.7 3.9 -3.0 -4.5 -4.5 -4.3 0.3 -4.6 -4.0 -4.5 -4.7 -4.7 -3.1 -4.7 -1.3 -3.2 -2.5 -4.3 -4.6 -3.2 -3.8 -4.5 -4.9 -4.2 -4.6 -4.3
Blood Platelet Count 0.3 4.0 9.1 -2.0 -1.6 -1.7 -1.8 -2.2 -1.6 -1.7 -1.6 -1.0 -2.7 -2.7 -2.0 0.0 -2.9 -1.6 -2.2 -2.7 -1.8 -1.8 1.1 -2.0 -1.9 -1.6 -2.4 -1.0 -2.0 -0.7 -2.3 -1.3 -1.7 -2.1 -1.7 -2.5 -2.6 -2.0 -2.1 -2.0 -2.4 -3.0 -1.8 -1.6 -2.4 -1.7 -2.3
Blood Red Count 1.6 15.4 25.7 4.3 4.7 4.5 4.0 3.3 4.0 4.2 4.7 4.9 2.9 3.0 4.8 2.0 2.0 4.0 4.2 3.3 4.4 4.5 -3.8 2.9 4.3 4.8 4.2 1.6 4.3 5.1 4.3 4.5 4.7 2.8 4.5 1.3 2.5 2.4 3.9 4.5 2.9 3.5 4.4 4.5 3.7 4.5 4.0
Blood White Count 0.3 2.4 6.9 -1.8 -1.6 -1.3 -1.1 -1.1 -2.3 -1.7 -1.4 -0.7 -2.5 -2.6 -1.7 0.3 -0.4 -1.1 -2.0 -1.9 -1.2 -0.4 1.1 -1.0 -1.5 -1.4 -1.9 0.4 -1.9 -0.7 -1.8 -1.6 -1.5 -1.1 -1.6 -1.6 -1.6 -0.7 -1.6 -1.6 -2.2 -2.5 -1.3 -1.5 -1.8 -1.4 -1.9
Heel T-Score 3.5 28.2 58.2 -5.6 -6.3 -6.3 -6.0 -5.1 -4.4 -6.0 -6.0 -5.2 -4.0 -3.6 -5.6 -3.4 -4.1 -5.6 -5.8 -4.8 -6.0 -5.9 4.9 -5.2 -5.3 -5.9 -5.6 -1.6 -6.0 -6.2 -5.5 -5.4 -5.8 -3.2 -6.2 -1.1 -4.4 -4.7 -3.0 -5.9 -5.7 -4.3 -6.2 -7.6 -5.3 -5.9 -6.6
BMI 0.0 0.3 1.9 -0.1 -0.6 -0.7 -0.6 -0.4 0.4 -0.5 -0.5 -0.5 0.5 0.6 -0.1 0.7 0.4 -0.6 -0.9 0.2 -0.7 -0.6 0.1 -0.1 -0.0 -0.5 -0.3 1.4 -0.3 -0.7 -0.2 -0.2 -0.4 -0.3 -0.5 -0.5 0.0 -0.6 0.2 -0.4 0.1 -1.0 -0.5 -0.8 -0.1 -0.4 -0.7
Height 0.7 14.5 20.5 4.5 4.3 4.1 3.5 2.3 4.2 4.2 4.3 4.0 4.4 4.0 3.6 1.9 2.8 4.0 4.4 3.6 3.9 3.6 -4.0 3.9 3.6 4.1 4.2 0.9 4.5 4.0 3.9 4.4 4.4 2.9 4.4 1.5 3.0 1.7 3.4 4.4 3.9 3.5 4.0 4.5 4.0 4.0 4.3
Waist Hip Ratio (WHR) 0.6 2.5 4.8 1.6 1.8 1.6 1.4 1.0 1.8 2.1 1.8 2.0 0.9 1.0 1.9 1.5 2.2 1.7 1.4 0.9 1.1 2.1 -2.2 1.9 1.9 1.8 2.0 1.9 1.6 1.6 1.5 1.9 1.8 1.1 1.7 -0.4 0.4 0.2 0.9 1.6 1.4 0.5 1.7 1.6 1.1 1.9 1.2
Systolic Blood Pressure 0.1 0.4 1.7 -0.4 -0.3 -0.5 -0.5 -1.0 -0.8 -0.5 -0.2 0.1 -0.7 -0.6 -0.1 -0.7 -0.4 -0.3 -0.6 -1.0 -0.8 -0.1 -0.4 -0.1 -0.6 -0.2 -0.2 1.0 -0.5 0.0 -0.7 -0.0 -0.3 -0.1 -0.4 -1.0 -1.1 -1.1 0.2 -0.4 -1.3 -1.1 -0.5 -1.1 -0.8 -0.4 -0.7
Smoking Status 0.2 0.4 3.0 0.4 0.4 0.6 0.7 0.8 0.4 0.6 0.4 -0.1 0.4 0.2 0.3 1.3 0.5 0.7 -0.1 0.6 0.5 0.8 -0.3 0.3 0.1 0.3 0.5 1.7 0.3 0.6 0.3 0.2 0.3 0.8 0.4 1.1 0.9 0.9 -0.1 0.5 0.7 0.3 0.6 0.1 0.7 0.3 0.6
Allergy or Eczema 1.0 2.7 5.2 -1.6 -1.4 -1.7 -2.0 -2.2 -1.6 -1.3 -1.4 -0.9 -1.8 -1.7 -1.6 -1.1 -2.0 -1.8 -1.7 -2.2 -1.5 -1.7 0.9 -1.9 -1.7 -1.3 -1.8 -1.4 -1.6 -1.1 -1.7 -1.1 -1.3 -2.1 -1.5 -1.2 -2.3 -2.2 -1.3 -1.6 -1.4 -1.2 -1.8 -1.4 -2.0 -1.6 -1.5
Cardiovascular Disease 0.7 2.3 8.1 -1.1 -1.1 -1.4 -1.8 -2.2 -0.7 -1.3 -1.0 -0.1 -1.4 -1.1 -1.1 -0.8 -1.8 -1.3 -1.7 -2.0 -2.0 -1.3 -0.3 -1.7 -1.0 -0.9 -1.0 0.1 -1.2 -0.7 -1.5 -0.5 -1.0 -2.1 -1.1 -2.4 -2.4 -2.7 -0.1 -1.3 -2.1 -2.9 -1.5 -1.7 -1.9 -1.1 -1.7
Hypothyroidism (self reported) 7.2 16.4 23.7 -4.5 -4.2 -4.1 -3.9 -3.6 -4.9 -4.1 -4.2 -4.0 -4.6 -4.4 -4.0 -3.8 -2.7 -3.8 -4.1 -4.5 -3.9 -4.1 3.3 -3.6 -4.5 -4.2 -3.5 -1.1 -4.5 -3.4 -4.7 -4.3 -4.5 -3.3 -4.4 -2.5 -3.9 -2.8 -4.6 -4.5 -4.5 -4.2 -4.2 -4.6 -4.5 -4.3 -4.6
Respiratory disease 0.1 0.2 1.2 0.3 0.6 0.5 0.2 0.1 0.6 0.6 0.6 1.1 -0.4 -0.4 0.3 0.6 0.1 0.1 0.4 -0.2 0.7 0.3 0.1 0.2 0.2 0.6 0.5 -0.6 0.2 1.0 0.4 0.5 0.7 -0.2 0.5 -0.2 -0.3 -0.1 -0.1 0.5 -0.1 0.3 0.5 0.6 0.1 0.4 0.6
Type 2 Diabetes (T2D) (2018) 2.6 5.0 8.0 -2.3 -2.2 -2.5 -2.5 -2.2 -1.6 -1.8 -2.2 -1.5 -2.2 -2.1 -2.0 -1.7 -2.5 -2.3 -2.6 -2.4 -2.3 -2.4 1.8 -2.4 -2.0 -2.2 -2.7 -1.5 -2.3 -1.6 -2.2 -2.1 -2.1 -2.6 -2.3 -2.6 -2.4 -2.2 -1.9 -2.3 -2.4 -2.8 -2.4 -1.7 -2.5 -2.2 -2.4
Lung FEV1/FVC ratio 0.6 3.1 5.4 1.9 2.1 1.8 1.8 1.4 1.7 2.1 2.1 2.2 1.1 1.1 2.2 0.9 1.6 1.8 1.7 1.3 1.8 1.9 -1.6 1.9 1.7 2.2 1.6 2.3 1.9 2.2 1.8 1.9 2.0 1.4 2.0 0.7 1.1 1.1 1.9 2.0 1.5 1.2 2.0 1.6 1.6 2.0 1.8
Lung FVC 0.1 0.4 2.8 0.3 -0.2 -0.1 -0.1 -0.0 0.9 -0.7 -0.1 -0.3 1.4 1.5 0.1 -0.9 -0.7 -0.3 0.2 0.9 0.3 -0.4 0.9 -0.3 -0.4 -0.2 0.0 0.2 0.1 -0.2 0.3 -0.1 0.1 0.2 -0.0 1.7 1.0 0.1 0.3 0.2 0.1 1.3 -0.1 -0.4 0.7 -0.3 0.5
Neuroticism 1.1 2.6 8.2 -1.5 -1.2 -1.2 -1.8 -2.2 -1.6 -1.1 -1.1 -0.8 -2.2 -1.8 -1.2 -2.3 -1.6 -1.3 -1.6 -2.4 -1.8 -1.9 -0.3 -2.8 -1.0 -1.1 -0.7 -0.2 -1.5 -0.5 -1.8 -0.7 -1.2 -1.5 -1.3 -0.9 -2.9 -2.5 -0.6 -1.6 -1.7 -1.8 -1.5 -2.0 -2.2 -1.1 -2.0
Chronotype (morning person) 0.2 0.5 2.8 -0.1 0.4 0.6 1.1 1.4 -0.9 0.1 0.2 -0.6 -0.8 -1.1 0.5 0.2 1.4 1.0 -0.2 0.1 0.6 0.7 -0.6 0.7 0.5 0.2 0.4 0.7 0.2 1.0 0.1 -0.3 -0.1 0.9 0.3 1.0 0.5 1.7 -0.6 0.1 1.1 -0.1 0.6 0.5 0.1 0.4 0.3
Hair Pigment 0.0 0.9 5.8 0.7 0.6 1.2 1.6 1.1 -0.3 0.5 0.6 -0.5 0.7 0.6 0.5 0.0 0.4 1.6 0.8 1.0 0.5 1.5 -1.2 0.2 -0.2 0.5 0.9 0.2 0.4 0.2 -0.0 0.3 0.3 2.4 0.6 2.1 1.5 1.5 0.4 0.6 0.6 0.9 0.9 -0.5 1.1 0.4 0.4
Tanning 0.2 2.0 4.7 1.5 1.7 1.3 0.9 0.6 1.8 1.5 1.7 2.2 1.0 1.1 1.7 0.6 0.8 1.2 1.8 0.9 1.8 1.3 -1.3 1.6 1.7 1.7 1.3 -2.1 1.7 1.6 1.7 1.7 1.9 0.2 1.6 -1.1 0.3 0.1 1.1 1.6 0.7 0.9 1.4 2.1 1.1 1.7 1.3
Hand grip strength (left) 0.3 0.7 2.5 1.0 0.8 0.6 0.6 0.2 1.4 1.0 0.8 0.8 1.2 1.2 0.7 0.7 -0.5 1.1 0.9 0.7 0.0 0.8 -1.6 -0.0 0.9 0.8 0.6 1.0 0.9 0.4 0.7 1.0 0.9 1.1 0.9 -0.3 0.5 -0.3 0.9 0.8 0.8 0.3 0.7 0.7 0.8 0.8 0.5
Number of treatments/medications taken 1.5 2.6 6.0 -1.8 -1.7 -1.8 -1.7 -1.3 -1.4 -1.9 -1.7 -1.3 -1.7 -1.7 -1.7 -0.8 -1.3 -1.9 -2.5 -1.5 -1.6 -1.9 1.9 -1.1 -1.5 -1.8 -1.9 -0.7 -1.8 -2.0 -1.5 -1.8 -1.7 -1.7 -1.8 -1.2 -1.4 -1.2 -1.6 -1.7 -1.3 -1.7 -1.7 -1.3 -1.7 -1.7 -1.4
Average weekly spirits intake 0.2 0.2 1.9 0.3 0.5 0.4 0.0 -0.1 0.4 0.8 0.4 0.3 -0.2 -0.0 0.5 1.4 0.3 0.2 0.4 -0.2 -0.2 0.4 -1.0 -0.1 0.7 0.4 0.4 0.1 0.4 0.8 0.2 0.6 0.4 -0.6 0.5 -0.8 -0.6 -0.7 0.1 0.2 -0.3 -0.6 0.2 0.1 -0.2 0.5 -0.0
Sensitivity / hurt feelings 0.2 0.3 1.6 -0.2 -0.2 -0.3 -0.7 -1.0 -0.2 -0.4 -0.2 -0.1 -0.5 -0.1 -0.1 -0.9 -0.6 -0.3 -0.1 -0.7 -0.4 -0.7 -0.6 -1.0 -0.1 -0.1 -0.1 -0.7 -0.2 -0.1 -0.5 0.1 -0.2 -0.5 -0.2 -0.2 -1.2 -1.2 0.7 -0.4 -0.3 -0.1 -0.5 -0.5 -0.7 -0.1 -0.7
Frequency of depressed mood in last 2 weeks 0.0 0.1 0.4 -0.0 0.0 0.2 0.0 -0.1 -0.1 0.4 0.1 0.2 -0.2 -0.2 0.1 -0.7 0.6 -0.2 -0.2 -0.2 -0.2 0.2 -0.7 0.2 0.1 0.0 0.7 -0.1 -0.0 0.2 -0.1 0.3 -0.0 -0.2 0.0 0.1 -0.3 -0.2 0.4 -0.1 0.2 -0.3 0.0 -0.1 -0.1 0.1 0.1
Hearing difficulty/problems: Yes 0.9 1.4 3.3 -1.5 -1.3 -0.9 -1.1 -0.6 -1.6 -1.0 -1.2 -1.1 -1.7 -1.8 -1.3 -1.8 -0.6 -1.3 -1.3 -1.4 -0.9 -1.3 1.7 -1.3 -1.0 -1.2 -0.7 0.2 -1.3 -0.7 -1.1 -1.3 -1.3 -0.8 -1.3 1.0 -1.1 -0.3 -0.8 -1.3 -1.1 -0.2 -1.1 -1.4 -1.4 -1.1 -1.0
Relative age of first facial hair 1.4 2.8 6.0 -1.8 -2.0 -1.9 -2.0 -1.5 -1.7 -1.9 -1.9 -1.5 -1.2 -1.2 -2.0 -2.2 -1.3 -2.3 -1.5 -1.5 -1.2 -1.9 2.5 -1.4 -1.8 -1.9 -2.1 -0.1 -1.9 -1.8 -1.5 -1.7 -1.8 -2.0 -1.9 -0.5 -1.1 -1.1 -1.6 -1.7 -1.8 -0.5 -1.9 -1.5 -1.6 -1.9 -1.2
Other serious medical condition/disability diagnosed by doctor 1.7 2.3 5.9 -1.9 -1.7 -1.4 -1.0 -0.4 -2.4 -1.9 -1.8 -2.2 -1.8 -2.0 -1.7 -1.3 -0.1 -1.1 -2.0 -1.1 -1.4 -1.5 1.4 -1.1 -1.4 -1.8 -1.3 0.4 -1.7 -1.8 -1.6 -1.9 -2.0 -0.6 -1.7 0.3 -0.7 0.1 -1.9 -1.8 -0.5 -1.1 -1.4 -1.5 -1.4 -1.6 -1.5
Ever used hormone-replacement therapy (HRT) 0.6 0.8 3.5 1.0 0.8 0.9 1.0 0.5 0.1 0.9 0.8 0.4 1.1 1.1 0.8 1.1 0.7 1.1 0.6 0.9 0.8 0.5 -1.2 0.5 0.5 0.8 0.7 1.9 0.8 0.5 0.6 0.9 0.8 1.3 0.8 0.8 0.9 0.6 0.7 0.9 1.4 0.7 0.8 0.6 1.0 0.7 0.7
Ever had hysterectomy (womb removed) 1.1 1.3 6.0 -0.6 -0.9 -1.1 -1.5 -2.1 -0.4 -0.9 -0.7 -0.0 -0.4 -0.1 -0.9 -0.3 -1.1 -1.0 -0.9 -1.3 -1.0 -1.1 -0.6 -1.3 -0.8 -0.7 -0.9 1.6 -0.7 -1.0 -1.1 -0.1 -0.6 -1.5 -0.8 -1.8 -1.7 -2.5 -0.0 -0.9 -1.2 -1.7 -1.2 -1.2 -1.2 -0.8 -1.3
Systolic blood pressure, automated reading 0.1 0.3 3.2 0.4 0.1 0.1 0.2 -0.2 0.3 0.1 0.2 -0.1 0.7 0.9 0.2 1.1 0.2 0.4 -0.3 0.2 -0.3 0.1 -0.6 0.3 -0.2 0.1 0.4 1.8 0.0 -0.2 -0.1 0.3 0.1 1.1 0.1 0.8 0.3 -0.3 0.9 0.2 0.1 -0.2 0.1 -1.1 0.3 0.0 -0.2
Eye problems/disorders: Diabetes related eye disease 1.1 1.2 2.6 -1.2 -1.3 -1.1 -0.7 0.0 -1.1 -1.4 -1.4 -1.5 -0.8 -1.1 -1.2 -0.2 -1.0 -1.1 -0.9 -0.5 -1.6 -1.5 1.6 -0.7 -0.6 -1.4 -1.5 -0.4 -1.2 -1.3 -0.8 -1.4 -1.4 -0.8 -1.2 -0.6 -0.1 0.2 -1.3 -1.2 -0.6 -1.2 -1.0 -0.8 -0.8 -1.1 -0.8
Angina 0.7 0.9 3.4 -0.8 -0.6 -0.8 -1.0 -1.4 -1.1 -0.3 -0.5 0.0 -1.4 -1.4 -0.3 -1.2 -1.4 -0.6 -0.8 -1.5 -0.3 -0.5 -0.2 -1.1 -0.8 -0.3 -0.7 -1.1 -0.8 -0.2 -0.9 -0.2 -0.5 -1.3 -0.7 -1.8 -1.7 -1.4 -0.7 -0.7 -1.0 -1.4 -0.7 -0.6 -1.3 -0.6 -0.8
Medication for hormone replacement therapy 0.1 0.1 1.8 -0.1 -0.1 0.1 -0.1 -0.7 -0.7 0.0 -0.0 -0.0 -0.1 -0.2 -0.2 0.8 0.0 -0.0 -0.3 -0.5 -0.1 -0.2 -0.7 -0.4 -0.5 -0.1 0.1 1.3 -0.1 -0.3 -0.5 0.1 -0.1 0.1 -0.0 0.3 -0.4 -0.4 -0.1 -0.1 -0.0 -0.2 -0.1 -0.2 -0.3 -0.2 -0.4
Vitamin and mineral supplements 0.9 1.3 3.3 1.4 1.2 1.1 1.1 0.5 1.2 1.3 1.3 0.9 1.2 1.1 1.6 -0.1 0.1 1.0 1.4 0.9 1.0 1.2 -1.4 0.7 1.1 1.4 1.3 -1.1 1.3 1.5 1.0 1.6 1.3 0.9 1.2 0.9 0.7 0.3 1.8 1.3 0.8 1.0 1.1 0.0 1.1 1.2 0.8
Supplements: Zinc 0.1 0.1 0.6 0.1 -0.0 -0.1 0.2 0.6 0.7 -0.2 -0.0 0.1 0.4 0.5 -0.1 0.2 -0.0 -0.0 -0.0 0.5 0.2 -0.1 0.3 0.5 0.1 -0.2 -0.3 0.5 0.0 -0.4 0.3 -0.2 0.0 0.1 -0.0 -0.3 0.8 0.6 -0.4 0.1 0.3 -0.1 0.1 0.3 0.4 -0.1 0.3
Medication: Co-codamol 1.6 1.8 3.0 1.3 1.6 1.4 1.5 1.5 1.7 1.6 1.5 1.4 1.0 0.9 1.6 1.4 1.0 1.4 1.6 1.2 1.7 1.5 -1.1 1.5 1.6 1.5 1.3 0.4 1.4 1.4 1.5 1.3 1.4 0.7 1.5 0.2 1.0 1.2 0.6 1.4 1.5 1.2 1.5 1.7 1.3 1.5 1.5
Medication: Metformin 0.3 0.5 2.0 -0.5 -0.4 -0.4 -0.5 -0.7 -0.8 -0.3 -0.5 -0.6 -0.7 -0.6 -0.3 0.8 -1.2 -0.3 -0.8 -0.7 -1.2 -0.1 -0.6 -1.3 -0.2 -0.5 -0.8 -0.6 -0.4 -0.2 -0.8 -0.2 -0.5 -0.5 -0.4 -0.4 -0.9 -0.8 -0.2 -0.7 -0.5 -1.4 -0.5 -0.8 -0.7 -0.3 -1.0
Diabetes (father) 3.4 4.2 7.3 -2.5 -2.3 -2.1 -1.8 -1.3 -2.7 -2.3 -2.3 -2.2 -2.3 -2.4 -2.3 -2.1 -1.5 -2.1 -1.6 -2.0 -2.1 -2.3 2.2 -2.3 -2.1 -2.3 -2.1 -0.1 -2.2 -2.1 -2.1 -2.4 -2.4 -1.5 -2.3 -1.2 -1.6 -0.5 -2.4 -2.3 -1.7 -1.6 -2.1 -1.6 -2.1 -2.1 -2.3
Diabetes (mother) 1.3 1.6 3.8 -1.2 -1.6 -1.5 -1.5 -1.5 -0.9 -1.6 -1.6 -1.5 -0.3 -0.2 -1.4 0.2 -0.5 -1.4 -1.6 -0.7 -1.4 -1.2 1.3 -1.1 -1.7 -1.6 -1.1 0.1 -1.3 -2.0 -1.5 -1.5 -1.5 -0.8 -1.4 -0.4 -0.6 -1.1 -1.0 -1.4 -1.3 -1.0 -1.6 -1.5 -1.0 -1.7 -1.4
Severe depression (siblings) 1.5 1.7 7.6 -1.7 -1.1 -0.8 -0.2 0.3 -2.2 -1.0 -1.2 -2.0 -2.5 -2.8 -1.3 -0.6 -0.5 -0.4 -1.8 -1.3 -1.0 -1.1 0.8 -0.9 -0.8 -1.2 -1.3 0.2 -1.6 -0.6 -1.4 -1.8 -1.6 0.1 -1.3 0.8 -0.8 0.7 -1.8 -1.5 -0.4 -1.2 -0.7 -1.8 -1.3 -1.0 -1.5
Pack years adult smoking proportion 0.8 1.2 6.0 -1.4 -0.6 -0.6 -0.5 -0.0 -1.6 -0.7 -0.8 -1.2 -2.4 -2.5 -1.1 0.7 0.0 -0.7 -1.4 -1.6 -1.0 -0.8 0.6 -1.1 -0.5 -0.8 -0.6 1.3 -1.2 -0.4 -1.0 -1.3 -1.0 -1.3 -0.8 -0.0 -1.3 0.0 -2.0 -1.1 -0.1 -1.0 -0.6 -0.6 -1.5 -0.7 -0.5
Impedance of leg (right) 0.1 0.5 2.3 -0.7 -0.5 -0.5 -0.5 -0.6 -0.8 -0.5 -0.4 0.1 -1.1 -1.1 -0.7 0.1 -1.5 -0.5 -0.6 -1.0 -0.3 -0.5 1.0 -1.0 -0.8 -0.3 -0.6 0.9 -0.7 -0.0 -0.6 -0.4 -0.4 -0.8 -0.6 -1.4 -0.8 -0.5 -0.5 -0.5 -1.5 -0.8 -0.5 -0.1 -0.8 -0.6 -0.5
Leg fat-free mass (left) 0.6 3.4 6.5 2.1 1.8 1.8 1.8 1.5 2.0 1.9 1.8 1.1 2.4 2.2 1.9 1.5 2.1 2.1 1.8 2.2 1.3 2.0 -2.5 2.2 2.1 1.7 1.9 0.5 2.1 1.4 1.8 1.9 1.8 2.0 1.9 1.3 1.8 1.0 1.8 1.9 2.5 1.2 1.8 1.4 2.1 1.9 1.6
Trunk fat percentage 0.2 0.9 5.1 0.9 1.0 0.8 1.1 1.0 0.8 1.0 1.0 0.7 0.5 0.5 1.3 2.3 0.9 1.2 0.1 0.9 0.7 1.1 -1.4 1.0 1.3 0.9 0.8 1.4 0.9 1.1 0.9 1.0 0.9 0.7 0.9 -0.5 0.6 0.7 1.1 0.9 0.9 -0.5 1.0 0.8 0.8 1.1 0.6
Hand grip strength (right) 0.2 0.5 2.8 0.9 0.6 0.5 0.4 0.1 1.2 0.9 0.7 0.6 1.1 1.2 0.5 0.7 -0.5 0.9 0.6 0.6 -0.2 0.5 -1.7 -0.2 0.7 0.5 0.7 0.9 0.6 0.4 0.5 0.9 0.8 1.0 0.7 -0.4 0.4 -0.5 0.8 0.7 0.3 -0.2 0.5 0.1 0.7 0.6 0.2
Townsend deprivation index at recruitment 0.2 0.4 3.7 0.2 0.4 0.6 0.8 0.7 -0.4 0.3 0.2 -0.5 0.1 -0.2 -0.3 1.9 0.2 0.6 -0.3 0.5 0.1 0.8 -0.2 0.1 -0.1 -0.0 0.1 -0.2 0.2 -0.3 -0.0 -0.1 0.1 0.4 0.4 1.3 0.8 0.9 -1.0 0.2 1.4 0.2 0.5 0.2 0.6 0.1 0.6
Current tobacco smoking 0.4 0.7 4.6 -0.9 -0.5 0.1 0.3 0.9 -1.2 -0.4 -0.7 -1.6 -1.2 -1.6 -1.1 0.8 0.0 -0.1 -1.0 -0.2 -0.3 -0.2 0.8 -0.5 -0.6 -0.9 -0.5 1.0 -0.8 -0.3 -0.7 -1.2 -0.9 0.3 -0.5 2.1 0.4 1.3 -1.7 -0.7 0.3 0.3 -0.2 -0.5 -0.3 -0.6 -0.2
Average weekly fortified wine intake 0.5 0.6 2.1 -0.8 -0.9 -1.0 -0.8 -0.7 -0.5 -0.8 -1.0 -1.4 -0.5 -0.5 -0.7 -0.8 -0.8 -0.6 -0.9 -0.7 -1.1 -1.0 0.1 -0.7 -0.8 -1.0 -0.7 -0.7 -0.8 -0.7 -1.0 -0.8 -1.0 -0.3 -0.9 0.2 -0.6 -0.5 -0.5 -1.0 -0.3 -0.6 -1.0 -1.1 -0.8 -0.9 -1.1
Maternal smoking around birth 0.9 1.3 2.9 1.3 1.2 1.2 1.2 0.8 1.0 1.2 1.2 1.1 1.1 1.0 1.1 1.0 1.5 1.4 1.1 1.1 1.2 1.2 -1.3 1.7 0.7 1.2 1.5 1.5 1.1 1.3 0.9 1.1 1.2 1.0 1.2 0.3 1.0 0.6 0.8 1.2 0.6 0.4 1.2 0.5 1.2 1.0 1.1
Fed-up feelings 0.8 1.5 4.4 -1.0 -1.0 -1.2 -1.6 -1.8 -0.6 -0.8 -0.9 -0.2 -1.3 -0.9 -0.8 -1.2 -1.3 -1.2 -1.2 -1.6 -1.3 -1.3 0.0 -1.2 -0.7 -0.9 -1.0 -1.4 -1.0 -0.6 -1.1 -0.5 -0.8 -1.6 -1.0 -1.8 -2.0 -2.1 -0.1 -1.1 -1.5 -1.7 -1.2 -1.0 -1.5 -0.8 -1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.8 -0.5 -0.2 -0.3 -0.8 -1.0 -0.2 0.0 -0.2 0.2 -1.2 -1.0 -0.1 -0.0 -0.6 -0.7 -0.2 -1.2 -0.6 -0.6 -0.4 -1.0 -0.0 -0.1 -0.1 -0.7 -0.4 0.4 -0.6 0.1 -0.2 -1.4 -0.3 -0.7 -1.7 -1.3 0.1 -0.5 -0.4 -0.7 -0.5 -0.2 -1.1 -0.1 -0.5
Relative age voice broke 0.6 0.9 2.8 -1.1 -1.0 -0.9 -0.9 -0.5 -1.4 -0.8 -1.1 -1.3 -1.0 -1.2 -1.3 -0.6 -0.8 -1.0 -1.3 -0.8 -0.9 -1.0 0.9 -0.6 -0.8 -1.2 -1.1 0.1 -1.1 -0.6 -0.9 -1.1 -1.1 -0.9 -1.0 0.5 -0.7 -0.5 -1.0 -1.1 -0.9 -0.6 -1.0 -1.7 -0.9 -1.0 -0.8
Taking other prescription medications 0.7 1.1 3.3 -1.3 -1.0 -0.9 -0.6 -0.2 -1.5 -1.1 -1.0 -0.9 -1.6 -1.8 -1.2 -0.7 -0.8 -1.1 -1.5 -0.9 -0.6 -1.3 1.5 -0.7 -1.1 -1.1 -1.2 -0.7 -1.3 -0.9 -1.0 -1.2 -1.1 -1.1 -1.1 -0.3 -0.6 0.1 -1.6 -1.1 -0.7 -1.1 -0.8 -1.0 -1.0 -1.1 -0.8
Age when periods started (menarche) 0.1 0.2 2.0 0.3 0.2 0.6 0.4 0.2 -0.0 0.3 0.2 0.0 0.3 0.3 -0.3 1.2 0.8 0.6 0.1 0.4 0.5 0.4 -0.2 0.3 -0.1 0.1 0.6 1.0 0.2 0.1 0.1 0.1 0.2 1.1 0.2 1.4 0.5 0.5 0.0 0.2 0.2 0.8 0.3 0.2 0.4 0.1 0.3
Bilateral oophorectomy (both ovaries removed) 0.5 0.5 4.4 -0.2 -0.2 -0.5 -0.9 -1.8 -0.0 0.0 -0.1 0.2 -0.4 -0.3 -0.2 -0.4 0.2 -0.4 -0.4 -1.3 -0.5 -0.7 -1.2 -0.2 -0.5 -0.1 0.1 1.2 -0.2 -0.2 -0.8 0.4 -0.1 -0.9 -0.2 -0.3 -1.7 -2.1 0.4 -0.4 -0.1 -0.6 -0.6 -1.0 -1.0 -0.2 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 5.7 12.9 22.5 -3.5 -3.7 -4.0 -4.1 -4.4 -3.2 -3.2 -3.6 -2.9 -3.1 -2.8 -3.4 -2.6 -3.1 -3.4 -3.4 -4.1 -4.0 -3.9 2.5 -3.8 -3.9 -3.6 -3.5 -1.4 -3.8 -4.0 -4.1 -3.2 -3.5 -2.9 -3.8 -2.2 -3.9 -4.1 -2.7 -3.8 -3.7 -3.7 -4.0 -4.7 -4.0 -3.8 -4.4
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.7 -0.3 -0.7 -0.5 -0.4 -0.4 0.1 -0.5 -0.7 -0.8 0.6 0.6 -0.6 -0.2 0.2 -0.5 -0.4 0.2 -0.3 -0.3 0.2 0.3 -0.8 -0.6 -0.6 -0.0 -0.4 -0.8 -0.5 -0.5 -0.6 0.2 -0.5 0.5 0.4 -0.1 -0.2 -0.4 -0.1 0.4 -0.6 -0.3 0.0 -0.7 -0.3
Qualifications: CSEs or equivalent 1.5 2.0 4.8 -1.6 -1.3 -1.3 -1.1 -0.9 -1.8 -1.4 -1.4 -1.2 -1.9 -2.0 -1.6 0.4 -0.2 -1.3 -1.7 -1.6 -1.3 -1.4 1.0 -0.8 -1.4 -1.5 -1.1 0.6 -1.6 -0.7 -1.5 -1.5 -1.5 -1.5 -1.4 -2.1 -1.3 -0.7 -1.9 -1.5 -1.8 -2.2 -1.3 -1.0 -1.6 -1.4 -1.3
Serious illness, injury or assault to yourself 0.3 0.3 2.1 -0.1 -0.5 -0.4 -0.0 0.1 -0.2 -0.4 -0.6 -1.4 1.0 0.9 -0.5 0.3 -0.8 -0.2 -0.4 0.7 -0.7 -0.3 0.1 -0.4 -0.4 -0.7 -0.4 0.2 -0.2 -0.9 -0.3 -0.4 -0.6 0.5 -0.4 0.8 0.9 0.3 -0.2 -0.3 0.4 -0.0 -0.4 -0.9 0.4 -0.5 -0.1
High blood pressure 0.1 0.3 1.7 -0.0 -0.1 -0.3 -0.4 -0.8 -0.0 -0.6 -0.1 0.5 -0.1 0.1 0.0 0.5 -0.5 -0.2 -0.8 -0.5 -0.7 -0.1 -0.8 -0.4 -0.0 0.0 -0.0 0.9 -0.1 -0.2 -0.3 0.4 -0.1 -0.4 -0.2 -1.2 -0.8 -1.1 0.6 -0.2 -0.5 -1.3 -0.3 -0.5 -0.5 -0.0 -0.5
Hayfever, allergic rhinitis or eczema 1.1 2.4 7.2 -1.3 -1.2 -1.6 -2.0 -2.4 -0.9 -1.1 -1.1 -0.4 -1.7 -1.5 -1.2 -1.8 -2.2 -1.6 -1.4 -2.2 -1.3 -1.7 0.2 -1.7 -1.3 -0.9 -1.4 -2.1 -1.3 -0.6 -1.5 -0.6 -1.0 -2.0 -1.2 -1.6 -2.6 -2.7 -0.8 -1.3 -1.5 -1.3 -1.6 -1.4 -2.0 -1.2 -1.5
Multivitamins +/- minerals 1.7 2.1 3.0 -1.7 -1.6 -1.5 -1.7 -1.4 -1.5 -1.5 -1.6 -0.9 -1.7 -1.4 -1.7 -0.1 -0.2 -1.5 -1.5 -1.6 -1.4 -1.4 1.2 -1.0 -1.4 -1.6 -1.4 0.5 -1.7 -1.7 -1.5 -1.7 -1.5 -1.3 -1.6 -1.5 -1.6 -1.2 -1.6 -1.6 -1.5 -1.5 -1.6 -0.8 -1.7 -1.5 -1.4
Stomach or abdominal pain in last month 2.1 2.6 5.9 -1.6 -1.6 -1.5 -1.4 -1.3 -1.8 -1.8 -1.6 -1.9 -1.6 -1.7 -1.7 -1.7 -2.4 -1.4 -1.9 -1.5 -1.7 -1.6 1.4 -2.1 -1.5 -1.7 -1.5 -1.3 -1.7 -1.4 -1.7 -1.5 -1.7 -1.1 -1.6 -0.2 -1.3 -1.0 -1.8 -1.6 -1.1 -1.5 -1.5 -2.4 -1.6 -1.6 -1.7
Supplements: Glucosamine 0.1 0.2 0.9 -0.0 0.1 0.0 -0.3 -0.7 0.1 -0.1 0.1 0.5 -0.3 -0.1 -0.0 -0.3 -0.6 -0.1 0.2 -0.6 -0.2 0.1 -0.5 -0.5 -0.2 0.1 0.4 -0.4 -0.0 0.7 -0.2 0.3 0.1 -0.4 0.0 -0.9 -0.8 -0.9 0.1 -0.0 -0.7 -0.6 -0.1 -0.2 -0.4 0.0 -0.1
Diverticular disease/diverticulitis (self-reported) 3.0 3.5 9.8 2.3 2.3 1.7 1.0 -0.2 1.9 2.4 2.5 3.1 1.3 1.6 2.2 -0.5 -0.3 1.6 2.3 0.5 1.6 1.7 -2.5 0.8 2.0 2.5 1.8 -2.6 2.2 2.4 1.8 3.0 2.6 0.2 2.3 -1.2 -0.4 -1.1 2.6 2.2 1.0 0.7 1.8 1.6 1.1 2.3 1.6
Medication: Atenolol 0.1 0.1 0.8 -0.1 0.1 0.3 0.3 0.2 -0.6 -0.0 0.0 -0.3 -0.3 -0.4 0.3 0.0 -0.2 0.5 -0.4 -0.0 -0.2 0.4 -0.6 -0.3 0.0 -0.0 0.0 -0.7 -0.0 0.3 -0.3 -0.0 -0.1 0.9 0.0 0.4 -0.1 0.4 0.3 -0.1 0.1 -0.2 0.1 -0.0 -0.0 0.1 -0.1
Medication: Levothyroxine sodium 4.4 7.4 11.7 -3.0 -2.9 -2.7 -2.7 -2.6 -3.0 -2.6 -2.9 -2.6 -2.8 -2.8 -3.0 -1.8 -1.9 -2.6 -2.9 -3.0 -3.1 -2.7 2.0 -2.7 -2.9 -2.8 -2.2 -0.6 -3.1 -2.5 -3.2 -2.6 -3.0 -2.1 -2.9 -1.6 -2.6 -2.2 -2.8 -3.0 -2.9 -3.3 -2.9 -3.4 -3.0 -2.9 -3.2
Sitting height 0.3 2.0 5.1 -1.2 -1.6 -1.6 -1.7 -1.9 -0.8 -1.2 -1.5 -1.2 -0.4 -0.6 -1.8 -2.3 -1.5 -1.6 -1.1 -1.1 -1.4 -1.9 0.9 -0.9 -1.7 -1.6 -1.6 -0.3 -1.4 -1.2 -1.5 -1.1 -1.4 -1.2 -1.5 -0.7 -1.1 -1.8 -0.9 -1.4 -1.6 -1.2 -1.7 -1.9 -1.2 -1.6 -1.5
Chronic bronchitis/emphysema (father) 2.3 2.7 4.7 1.9 1.7 1.7 1.5 1.4 1.6 1.9 1.7 1.4 1.9 2.2 1.5 0.8 0.9 1.6 1.6 1.8 1.5 1.7 -1.6 1.6 1.8 1.7 1.7 -1.1 1.8 0.9 1.8 1.6 1.7 1.2 1.8 1.7 1.6 1.0 1.6 1.8 1.9 1.9 1.7 1.4 1.8 1.7 2.0
High blood pressure (mother) 2.4 3.4 12.7 -1.3 -1.6 -2.0 -2.5 -3.0 -0.8 -1.6 -1.4 -0.4 -1.0 -0.7 -1.4 -1.3 -3.1 -1.7 -1.1 -2.2 -2.2 -1.6 -0.1 -2.5 -1.2 -1.3 -1.9 -1.1 -1.4 -1.8 -1.6 -0.7 -1.2 -2.2 -1.5 -2.6 -2.8 -3.6 -0.4 -1.6 -2.3 -2.1 -2.0 -2.1 -2.1 -1.4 -2.2
Body mass index (BMI) 0.1 0.6 4.3 0.7 0.5 0.4 0.6 0.7 0.9 0.6 0.5 0.3 0.8 0.8 1.0 2.1 1.4 0.6 -0.1 0.9 0.2 0.7 -1.0 0.9 1.0 0.5 0.6 1.8 0.6 0.0 0.7 0.6 0.5 0.8 0.5 0.1 0.6 0.4 1.0 0.5 1.1 -0.4 0.6 0.1 0.7 0.7 0.2
Impedance of leg (left) 0.2 1.1 4.1 -1.0 -0.8 -0.8 -0.9 -0.9 -1.1 -0.8 -0.7 -0.2 -1.5 -1.5 -0.9 0.2 -1.8 -0.9 -0.9 -1.5 -0.7 -0.9 1.1 -1.3 -0.9 -0.7 -0.9 0.5 -1.0 -0.1 -1.0 -0.7 -0.8 -1.3 -0.9 -2.0 -1.3 -0.8 -0.7 -0.9 -1.9 -1.4 -0.8 -0.4 -1.2 -0.8 -0.9
Leg predicted mass (left) 0.6 3.2 6.4 2.1 1.8 1.8 1.7 1.4 1.9 1.9 1.7 1.1 2.4 2.2 1.9 1.4 2.1 2.0 1.7 2.1 1.2 2.0 -2.5 2.2 2.0 1.6 1.8 0.5 2.0 1.3 1.8 1.8 1.7 2.0 1.9 1.4 1.7 1.0 1.7 1.8 2.5 1.2 1.7 1.3 2.0 1.9 1.6
Trunk fat mass 0.4 1.7 5.9 1.4 1.3 1.2 1.3 1.1 1.3 1.4 1.3 1.1 1.2 1.1 1.6 2.4 1.4 1.5 0.7 1.3 1.0 1.5 -1.9 1.4 1.7 1.3 1.2 1.3 1.4 1.3 1.3 1.4 1.3 1.1 1.3 -0.2 0.9 0.6 1.6 1.3 1.4 -0.1 1.3 1.0 1.3 1.5 0.9
Waist circumference 0.2 0.6 3.1 0.7 0.6 0.6 0.7 0.8 0.8 0.7 0.6 0.3 0.7 0.7 0.9 1.8 1.7 0.8 0.2 0.9 0.2 0.8 -1.1 1.1 1.0 0.5 0.7 1.1 0.7 0.2 0.7 0.6 0.6 0.9 0.6 0.3 0.7 0.5 0.9 0.6 1.1 -0.1 0.7 0.3 0.8 0.8 0.3
Number of incorrect matches in round 0.4 0.7 2.5 0.6 0.7 0.9 1.2 1.4 0.0 0.8 0.8 0.4 0.3 0.2 0.7 0.8 1.0 1.1 0.3 0.9 0.8 0.8 -0.3 0.9 1.0 0.7 0.5 -0.4 0.7 0.6 0.9 0.5 0.6 1.6 0.6 1.3 1.0 1.6 0.7 0.8 1.2 0.9 1.0 0.6 0.9 0.9 0.8
Past tobacco smoking 0.7 1.3 2.3 -1.3 -1.2 -1.1 -1.1 -0.7 -1.4 -1.1 -1.3 -1.4 -1.3 -1.2 -1.4 -0.9 -0.4 -1.2 -0.6 -1.1 -1.3 -1.4 0.9 -1.2 -0.7 -1.3 -1.1 -1.5 -1.2 -1.5 -1.1 -1.3 -1.3 -1.1 -1.2 -0.4 -1.0 -0.7 -1.4 -1.4 -0.8 -0.8 -1.2 -1.0 -1.3 -1.1 -1.3
Alcohol usually taken with meals 0.3 0.5 1.7 0.6 0.6 0.4 0.5 0.4 0.7 0.5 0.6 0.4 0.5 0.4 1.1 -1.0 0.4 0.9 0.9 0.5 0.8 0.8 -0.9 0.8 0.8 0.8 0.7 0.5 0.8 0.5 0.7 0.6 0.6 1.3 0.5 0.6 0.3 0.5 1.0 0.6 0.8 1.2 0.6 0.6 0.5 0.8 0.2
Nervous feelings 2.0 3.8 5.5 -2.1 -2.1 -2.0 -2.1 -2.0 -2.3 -1.9 -2.1 -2.0 -1.8 -1.8 -2.3 -1.1 -1.0 -2.0 -2.3 -2.1 -1.9 -2.3 1.2 -1.7 -2.2 -2.2 -1.5 0.6 -2.2 -2.1 -2.3 -1.8 -2.2 -1.6 -2.1 -0.7 -1.9 -1.7 -1.5 -2.2 -1.8 -2.0 -2.2 -2.3 -2.1 -2.1 -2.1
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 5.2 -1.7 -1.4 -1.4 -1.2 -1.4 -2.0 -1.3 -1.4 -1.5 -2.0 -2.1 -1.4 -1.0 -1.1 -1.2 -1.7 -1.9 -1.7 -1.4 0.4 -1.6 -1.5 -1.4 -1.3 0.5 -1.7 -0.7 -1.9 -1.3 -1.6 -1.2 -1.5 -0.9 -1.8 -1.1 -1.5 -1.6 -1.1 -2.3 -1.4 -2.1 -1.8 -1.4 -1.7
Hearing difficulty/problems with background noise 0.2 0.3 1.7 -0.6 -0.2 0.0 -0.1 -0.1 -0.9 -0.1 -0.3 -0.6 -1.2 -1.3 -0.3 -0.3 -0.6 -0.1 -0.5 -0.8 -0.5 -0.4 -0.3 -1.0 -0.1 -0.3 -0.1 0.4 -0.3 0.2 -0.5 -0.3 -0.4 -0.0 -0.3 1.2 -0.8 -0.1 -0.1 -0.5 0.1 0.1 -0.2 -0.5 -0.7 -0.1 -0.5
Hair/balding pattern: Pattern 2 0.9 1.1 3.2 1.0 1.1 1.1 1.3 1.2 0.8 1.2 1.2 1.3 0.7 0.5 1.0 1.1 1.8 0.7 1.2 1.0 1.2 1.2 -0.5 1.8 0.7 1.1 0.9 0.2 1.0 0.9 1.0 1.1 1.1 0.6 1.1 0.2 1.1 1.3 0.6 1.2 0.8 0.5 1.3 1.0 1.2 1.0 1.1
Had menopause 0.7 0.8 3.5 0.8 0.3 0.6 0.8 0.8 0.3 -0.2 0.3 -0.2 1.8 1.9 0.1 1.8 0.4 0.8 0.1 1.6 0.4 0.7 -0.3 0.4 0.2 0.2 0.1 1.9 0.7 -0.3 0.5 0.3 0.4 1.5 0.5 1.3 1.8 1.1 0.6 0.6 1.4 0.7 0.5 0.7 1.4 0.3 0.8
Had other major operations 2.8 3.4 6.5 -2.0 -1.6 -1.9 -2.1 -2.2 -1.6 -1.9 -1.6 -1.0 -2.5 -2.2 -1.5 -1.7 -2.2 -2.0 -1.6 -2.5 -1.4 -2.2 1.5 -2.5 -1.9 -1.5 -1.7 -0.6 -1.8 -1.5 -1.9 -1.5 -1.6 -2.5 -1.7 -1.7 -2.6 -1.9 -1.7 -1.8 -1.6 -1.7 -1.9 -1.1 -2.4 -1.7 -1.7
Forced vital capacity (FVC) 0.1 0.4 1.5 -0.4 -0.7 -0.5 -0.5 -0.5 -0.3 -0.8 -0.8 -1.0 0.4 0.2 -0.6 -0.9 -1.2 -0.5 -0.3 0.0 -0.6 -0.5 0.8 -0.7 -1.0 -0.8 -0.7 -0.0 -0.5 -0.7 -0.6 -0.7 -0.7 -0.3 -0.5 0.7 0.3 -0.2 -0.8 -0.5 -0.2 0.2 -0.7 -0.5 -0.1 -0.8 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 5.8 13.4 20.1 -3.8 -3.9 -4.2 -4.0 -3.8 -3.3 -3.6 -3.9 -3.3 -3.3 -3.1 -3.5 -2.3 -3.2 -3.6 -3.5 -3.9 -4.2 -3.9 3.0 -3.9 -3.9 -3.8 -3.9 -0.9 -3.9 -3.9 -4.1 -3.6 -3.8 -2.9 -4.0 -2.5 -3.5 -3.4 -3.0 -4.0 -4.0 -3.8 -4.0 -4.5 -3.9 -3.9 -4.4
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 3.9 -1.0 -1.1 -1.3 -1.1 -0.9 -0.9 -1.1 -1.1 -0.9 -0.6 -0.6 -0.7 -2.0 -1.1 -1.1 -1.4 -0.7 -1.1 -1.3 0.5 -1.2 -0.8 -1.0 -1.1 -0.8 -0.9 -1.1 -0.8 -0.8 -1.0 -0.9 -1.1 -0.9 -0.8 -0.7 -0.8 -1.0 0.0 -1.0 -1.1 -0.7 -0.9 -0.9 -1.0
Qualifications: None of the above 0.1 0.2 1.4 0.4 0.5 0.4 0.3 -0.1 0.3 0.7 0.6 1.0 0.1 -0.0 0.4 1.2 0.5 0.4 0.2 -0.0 0.6 0.4 -0.0 0.6 0.2 0.6 0.5 0.2 0.3 -0.1 0.3 0.4 0.6 0.2 0.4 -0.1 -0.1 -0.2 0.1 0.5 0.9 0.0 0.4 0.8 0.2 0.4 0.5
Financial difficulties in last 2 years 0.6 0.8 2.3 0.4 1.1 1.2 1.2 1.4 0.3 1.0 1.0 0.7 -0.8 -0.8 0.9 0.2 0.9 0.8 1.0 0.2 1.3 0.4 -0.5 0.4 1.1 0.9 0.8 -1.5 0.6 1.4 0.9 0.5 0.8 0.3 0.9 1.0 0.2 1.4 -0.1 0.8 0.9 1.0 1.2 1.1 0.4 1.1 0.8
Mouth/teeth dental problems 1.8 2.8 16.1 -1.6 -1.6 -1.5 -1.5 -1.5 -1.8 -1.9 -1.5 -1.3 -1.5 -1.3 -1.5 -4.0 -1.9 -1.5 -0.8 -1.6 -1.7 -1.1 1.5 -1.9 -1.6 -1.4 -1.2 -2.8 -1.7 -1.7 -1.7 -1.6 -1.5 -1.2 -1.6 -1.1 -1.5 -1.2 -1.2 -1.6 -2.3 -1.0 -1.6 -1.7 -1.6 -1.6 -1.7
Heart attack 2.9 3.7 8.0 -1.9 -2.1 -2.1 -2.2 -2.2 -1.6 -2.0 -2.0 -1.3 -1.3 -1.3 -2.0 -2.3 -2.3 -2.4 -2.2 -1.7 -1.9 -2.1 2.2 -1.7 -2.3 -1.9 -2.2 -1.7 -2.1 -2.8 -2.0 -1.8 -1.9 -1.8 -2.1 -0.1 -1.6 -1.8 -1.3 -1.9 -1.3 -1.3 -2.2 -2.3 -1.8 -2.2 -1.8
Allergy 0.4 1.0 5.5 0.7 0.5 0.8 1.3 1.4 0.3 0.3 0.4 -0.3 1.3 1.1 0.6 0.8 2.0 1.0 0.6 1.5 0.5 1.0 -0.4 0.9 0.5 0.3 1.0 2.4 0.7 0.2 0.6 0.2 0.3 1.5 0.6 1.0 1.8 1.7 0.4 0.7 1.0 0.6 0.8 0.8 1.3 0.5 0.8
Pain all over the body in last month 0.1 0.2 1.2 0.2 -0.0 -0.2 -0.3 -0.1 0.6 0.1 0.0 0.2 0.6 0.7 0.2 -0.4 0.7 -0.1 0.4 0.3 0.1 -0.1 -0.3 0.0 0.6 0.0 0.1 -0.7 0.3 -1.1 0.5 0.2 0.2 0.2 0.0 0.5 0.0 -0.3 0.7 0.1 0.8 0.6 -0.1 0.1 0.1 0.2 -0.0
Diabetes (self-reported) 3.3 5.2 7.6 -2.5 -2.4 -2.4 -2.3 -2.0 -2.3 -2.1 -2.4 -2.1 -2.4 -2.5 -2.2 -1.4 -1.9 -2.3 -2.7 -2.4 -2.3 -2.6 1.8 -2.2 -2.2 -2.4 -2.6 -1.1 -2.4 -2.0 -2.5 -2.3 -2.4 -2.4 -2.4 -1.9 -2.2 -1.6 -2.4 -2.5 -2.0 -2.8 -2.4 -1.9 -2.5 -2.3 -2.5
Hayfever/allergic rhinitis (self-reported) 2.8 3.7 7.7 -1.8 -1.6 -2.0 -2.2 -2.6 -1.5 -1.5 -1.6 -0.8 -2.1 -2.2 -1.7 -1.9 -1.9 -1.8 -1.9 -2.5 -1.5 -1.8 0.8 -1.7 -2.1 -1.5 -1.6 -1.8 -1.8 -1.3 -2.1 -1.2 -1.6 -2.4 -1.8 -2.8 -2.6 -2.5 -1.7 -1.8 -2.4 -2.5 -2.0 -1.5 -2.3 -1.8 -2.0
Medication: Ramipril 0.3 0.3 1.6 -0.5 -0.7 -0.5 -0.3 0.1 -0.5 -0.9 -0.7 -0.9 -0.2 -0.2 -0.5 -0.3 -0.4 -0.6 -1.2 -0.0 -0.9 -0.2 0.7 -0.0 -0.1 -0.7 -0.9 -0.8 -0.5 -1.3 -0.3 -0.6 -0.7 -0.2 -0.6 0.5 0.1 0.1 -0.3 -0.6 0.2 -0.5 -0.5 -0.9 -0.3 -0.5 -0.5
Medication: Simvastatin 0.6 0.9 2.2 -1.0 -0.8 -0.8 -0.9 -0.8 -0.7 -0.8 -0.8 -0.5 -1.3 -1.1 -0.6 -0.7 -1.3 -1.1 -1.1 -1.1 -1.1 -0.6 0.5 -0.9 -0.4 -0.7 -0.9 -1.1 -0.8 -0.6 -0.8 -0.5 -0.8 -1.3 -0.9 -0.7 -1.3 -0.9 -0.0 -1.0 -1.5 -1.2 -0.9 -1.1 -1.2 -0.7 -1.1
Fluid intelligence score 0.8 1.6 3.6 -1.4 -1.4 -1.2 -1.1 -0.5 -1.4 -1.4 -1.5 -1.9 -0.9 -1.0 -1.4 -1.7 -1.6 -1.5 -1.1 -0.8 -1.0 -1.4 1.7 -1.7 -1.1 -1.4 -1.6 -1.2 -1.2 -1.2 -1.1 -1.5 -1.5 -0.9 -1.3 0.8 -0.5 -0.1 -1.1 -1.4 -0.9 0.1 -1.3 -1.1 -1.1 -1.3 -1.1
Illnesses of siblings 2.4 3.4 6.3 2.0 1.9 2.0 1.9 1.7 1.7 1.8 1.9 1.5 1.9 1.7 1.9 1.7 1.3 1.9 1.9 2.0 2.3 1.8 -1.1 1.9 1.6 1.9 1.7 0.1 2.0 1.9 2.0 1.8 1.9 1.6 2.0 1.4 1.9 1.6 1.2 2.0 2.1 2.4 1.9 2.5 2.1 1.8 2.2
Neuroticism score 0.9 2.0 7.1 -1.4 -1.0 -1.0 -1.5 -1.7 -1.4 -0.9 -1.0 -0.7 -2.3 -2.0 -0.9 -2.3 -1.0 -1.1 -1.4 -2.2 -1.5 -1.7 -0.3 -2.0 -0.7 -0.9 -0.7 -0.3 -1.2 -0.4 -1.5 -0.7 -1.1 -1.5 -1.1 -0.7 -2.7 -1.9 -0.1 -1.4 -1.4 -1.5 -1.3 -1.3 -2.0 -0.8 -1.8
Weight 0.6 2.9 5.6 2.0 1.7 1.5 1.5 1.3 2.0 1.8 1.7 1.4 2.0 2.0 2.0 2.4 2.0 1.8 1.3 1.9 1.2 1.8 -2.3 2.0 2.0 1.7 1.7 1.4 1.9 1.2 1.7 1.9 1.7 1.6 1.8 0.5 1.4 0.7 1.9 1.7 2.2 0.6 1.7 1.3 1.8 1.8 1.3
Impedance of arm (right) 0.3 1.3 5.2 0.9 1.4 1.5 1.6 1.4 0.0 1.3 1.3 0.9 -0.0 -0.2 1.1 -1.1 -0.4 1.5 1.1 0.7 1.6 1.6 -1.0 0.7 0.8 1.3 1.0 -1.4 1.1 2.3 0.9 1.0 1.1 0.8 1.3 0.0 0.8 1.6 0.1 1.1 0.7 0.6 1.4 1.7 0.9 1.2 1.3
Arm fat percentage (right) 0.3 1.2 4.2 1.1 1.1 0.9 1.2 1.2 1.0 1.2 1.0 0.6 0.8 0.8 1.5 2.1 1.4 1.4 0.2 1.2 0.8 1.3 -1.7 1.1 1.4 1.0 1.0 1.5 1.1 0.9 1.0 1.0 1.0 1.1 1.0 -0.2 0.9 0.9 1.0 1.0 1.5 -0.4 1.1 0.8 1.1 1.2 0.6
Trunk fat-free mass 0.8 4.5 10.6 2.6 2.0 1.9 1.6 1.1 2.8 2.1 2.0 1.9 3.3 3.2 2.1 1.8 2.2 2.0 2.4 2.4 1.4 2.1 -2.5 2.4 2.2 2.0 2.2 0.7 2.5 1.2 2.2 2.4 2.2 2.0 2.2 1.2 1.8 0.4 2.3 2.2 2.6 1.9 1.9 1.8 2.4 2.1 1.9
Hip circumference 0.0 0.1 0.9 0.1 -0.1 -0.1 0.1 0.2 0.1 0.0 -0.1 -0.5 0.5 0.5 -0.1 0.9 0.3 0.2 -0.5 0.5 -0.3 0.0 -0.5 0.1 0.1 -0.2 -0.3 0.6 0.0 -0.5 -0.0 -0.1 -0.1 0.4 -0.0 0.2 0.5 0.2 0.2 -0.0 0.6 -0.6 -0.0 -0.3 0.3 -0.0 -0.1
Time employed in main current job 1.5 1.7 5.7 1.3 1.1 1.3 1.3 1.3 0.9 0.9 1.1 1.0 1.6 1.5 0.8 0.9 2.4 1.1 0.8 1.7 1.7 1.2 -0.5 2.0 0.9 0.9 1.5 0.8 1.2 0.5 1.3 0.9 1.1 1.1 1.3 1.5 1.8 1.5 0.8 1.3 1.7 1.6 1.2 1.7 1.6 1.0 1.6
Alcohol intake versus 10 years previously 0.6 1.0 3.7 -1.2 -0.9 -0.7 -0.9 -0.6 -1.9 -1.2 -0.9 -0.9 -1.5 -1.6 -0.8 -0.3 -0.7 -1.1 -1.1 -1.2 -0.8 -0.8 0.9 -1.1 -0.6 -1.0 -1.0 0.3 -0.9 -1.4 -0.9 -1.0 -1.1 -1.1 -0.9 0.1 -1.2 -0.4 -1.0 -1.1 -0.5 -0.7 -0.9 -0.8 -1.2 -0.7 -0.9
Father’s age at death 3.7 5.0 11.3 2.1 2.0 2.3 2.8 3.1 1.5 1.5 1.8 0.3 2.5 2.4 1.8 1.6 1.6 2.6 2.1 3.1 2.0 2.3 -1.4 2.1 2.0 1.7 1.9 1.3 2.0 1.4 2.2 1.4 1.7 3.2 2.1 3.2 3.4 3.3 1.3 2.1 2.9 3.1 2.4 1.7 2.9 2.0 2.2
Worrier / anxious feelings 0.4 0.7 4.7 -0.7 -0.5 -0.6 -0.9 -1.1 -0.7 -0.2 -0.3 0.4 -1.3 -1.4 -0.1 -2.2 0.3 -0.7 -0.4 -1.4 -0.4 -1.0 0.1 -0.6 -0.2 -0.3 -0.2 -0.6 -0.7 0.2 -0.6 -0.2 -0.3 -0.9 -0.6 -1.2 -1.8 -1.3 0.6 -0.6 -1.6 -0.8 -0.6 -0.6 -1.2 -0.3 -1.1
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.5 -0.5 -0.3 -0.5 -0.6 -0.6 -0.3 -0.1 -0.2 -0.0 -1.1 -1.0 0.1 -0.9 -0.7 -0.7 -0.3 -1.0 -0.4 -0.5 0.0 -0.7 -0.0 -0.2 -0.1 -0.9 -0.3 -0.2 -0.4 -0.0 -0.2 -1.1 -0.4 -0.9 -1.2 -0.8 -0.3 -0.5 -0.1 -0.6 -0.4 -0.3 -0.9 -0.1 -0.5
Falls in the last year 0.1 0.1 1.0 0.1 0.2 0.1 0.0 -0.6 -0.1 -0.0 0.2 0.0 -0.0 -0.2 0.0 0.7 0.0 0.3 0.1 -0.3 -0.0 0.1 -1.0 0.4 -0.4 0.1 0.1 0.5 0.2 0.8 -0.4 0.3 0.2 -0.2 0.2 -0.9 -0.4 -0.5 -0.6 0.0 0.1 -0.9 0.0 -0.1 -0.1 0.0 0.1
Hair/balding pattern: Pattern 3 0.1 0.2 0.7 0.3 0.5 0.7 0.5 0.3 -0.1 0.4 0.5 -0.1 -0.3 -0.5 0.5 -0.9 -0.4 0.6 0.5 0.0 0.2 0.5 -0.5 -0.3 0.5 0.4 0.6 0.1 0.4 0.6 0.2 0.4 0.3 0.3 0.5 0.6 -0.1 0.3 0.4 0.3 0.2 0.5 0.5 0.2 0.1 0.6 0.3
Number of live births 2.3 3.3 5.7 2.0 1.9 1.8 1.7 1.7 2.3 2.2 1.9 1.4 2.1 2.4 1.8 0.7 1.7 1.9 1.9 2.0 1.5 1.8 -1.5 1.2 2.2 1.9 1.9 0.9 2.0 1.5 2.1 1.8 1.9 1.9 1.9 2.1 1.6 1.0 2.0 1.9 1.9 2.2 1.9 1.0 1.9 2.0 1.7
Forced expiratory volume in 1-second (FEV1) 0.1 0.2 1.6 -0.3 -0.4 -0.4 -0.4 -0.5 -0.1 -0.7 -0.5 -0.6 0.3 0.2 -0.3 -0.5 -1.3 -0.4 -0.2 -0.1 -0.4 -0.4 0.5 -0.6 -0.9 -0.5 -0.6 0.4 -0.4 -0.3 -0.6 -0.5 -0.4 -0.3 -0.4 0.2 0.1 -0.3 -0.6 -0.4 -0.2 -0.1 -0.5 -0.3 -0.1 -0.6 -0.2
Pulse rate 2.5 4.2 6.6 -1.9 -2.3 -2.5 -2.6 -2.3 -1.4 -2.0 -2.2 -1.4 -1.1 -0.9 -2.5 -0.0 -1.6 -2.3 -2.3 -1.8 -2.2 -2.2 1.7 -2.1 -1.9 -2.2 -2.6 0.5 -2.1 -2.5 -2.0 -1.8 -2.0 -2.2 -2.2 -2.2 -1.8 -2.4 -1.3 -2.1 -2.4 -2.5 -2.4 -2.0 -2.0 -2.2 -2.2
Happiness 0.1 0.1 0.9 -0.1 -0.3 -0.2 -0.2 -0.1 0.2 -0.5 -0.3 -0.1 0.4 0.7 -0.3 0.1 -0.3 -0.4 -0.8 0.3 -0.5 -0.1 -0.3 0.1 -0.2 -0.4 -0.2 -0.9 -0.4 -0.4 -0.2 0.0 -0.2 -0.2 -0.3 -0.4 0.2 -0.2 -0.1 -0.2 0.0 -0.3 -0.3 0.1 0.1 -0.3 -0.0
Noisy workplace 0.3 0.4 3.9 0.4 0.6 0.7 0.6 0.4 0.1 1.0 0.6 0.8 -0.1 -0.0 0.4 1.1 0.8 0.6 -0.1 0.2 0.3 0.8 -0.4 0.4 0.5 0.6 0.5 2.0 0.3 0.9 0.3 0.5 0.5 0.2 0.5 -0.2 0.1 0.3 0.0 0.5 0.3 -0.5 0.7 0.3 0.3 0.6 0.5
Qualifications: A levels/AS levels or equivalent 0.2 0.5 6.4 -0.3 -0.7 -0.7 -0.8 -0.4 0.4 -0.8 -0.7 -0.9 0.5 0.7 -0.2 -2.5 -1.3 -0.7 0.0 0.1 -0.6 -0.5 0.5 -0.6 -0.1 -0.7 -0.6 -1.1 -0.2 -0.7 -0.1 -0.4 -0.5 -0.2 -0.6 0.4 0.0 -0.5 -0.0 -0.5 -0.4 0.5 -0.7 -0.7 -0.2 -0.5 -0.6
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 3.7 0.6 0.4 0.8 0.9 1.5 0.5 0.5 0.4 0.3 1.0 0.8 0.4 0.7 0.5 0.1 0.9 1.4 0.8 0.9 0.7 1.2 0.9 0.4 0.3 -0.9 0.7 -0.3 1.1 0.2 0.5 0.8 0.5 1.5 1.6 1.5 0.4 0.7 0.8 1.9 0.7 0.9 1.1 0.6 1.2
Mouth/teeth dental problems: Dentures 1.0 1.7 7.5 1.2 1.3 1.3 1.2 1.2 1.6 1.3 1.3 1.4 0.9 0.6 1.2 2.7 1.5 0.9 0.7 1.1 1.4 1.1 -0.6 1.8 1.3 1.2 0.9 1.7 1.4 1.6 1.5 1.3 1.3 0.5 1.3 1.1 1.0 1.1 1.2 1.4 1.2 1.3 1.3 1.5 1.2 1.3 1.4
Asthma 0.3 0.6 3.4 -0.7 -0.6 -0.8 -1.1 -0.8 -0.1 -0.8 -0.5 0.2 -1.0 -1.0 -0.9 -0.3 -0.9 -1.1 -0.6 -0.9 -0.2 -0.8 1.2 -0.4 -0.4 -0.5 -0.9 -1.9 -0.8 -0.6 -0.3 -0.5 -0.4 -1.4 -0.7 -0.7 -1.1 -1.1 -0.7 -0.6 -0.9 -0.5 -0.7 -0.4 -0.9 -0.6 -0.5
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 1.9 1.0 1.0 0.8 0.5 0.1 1.0 1.2 1.0 1.1 0.8 1.1 1.3 0.2 -0.5 0.8 1.4 0.5 1.0 0.7 -1.4 0.2 0.8 1.0 0.7 -0.5 1.1 0.9 0.8 1.1 1.1 0.3 1.0 -0.1 0.2 -0.1 1.0 1.0 0.4 0.8 0.8 0.7 0.7 1.0 0.8
Medication: Cholesterol lowering 2.0 3.1 6.5 -1.9 -1.8 -1.8 -1.6 -1.2 -1.7 -1.7 -1.8 -1.7 -1.9 -1.8 -1.7 -1.1 -2.2 -1.8 -2.5 -1.8 -2.1 -1.7 1.6 -2.1 -1.3 -1.8 -1.8 -1.4 -1.9 -1.3 -1.7 -1.8 -1.8 -1.8 -1.8 -0.8 -1.6 -1.1 -1.6 -1.9 -1.6 -2.0 -1.8 -1.8 -1.9 -1.7 -1.8
Depression (self-reported) 0.8 1.0 2.0 -0.9 -1.0 -1.0 -1.0 -1.2 -0.9 -0.8 -1.0 -1.0 -0.7 -0.6 -1.1 -1.2 -0.8 -0.8 -1.3 -0.9 -1.0 -1.2 0.4 -0.9 -1.1 -1.1 -0.9 -1.4 -1.0 -1.0 -1.1 -0.9 -1.0 -0.8 -1.0 -0.3 -0.9 -1.0 -1.1 -1.0 -0.5 -1.0 -1.1 -1.0 -0.9 -1.1 -0.9
Medication: Lansoprazole 0.1 0.1 0.7 -0.2 -0.2 -0.2 -0.3 -0.5 -0.6 -0.3 -0.1 0.0 -0.4 -0.7 -0.5 0.9 -0.5 -0.3 0.1 -0.5 -0.0 -0.4 0.2 -0.3 -0.3 -0.3 -0.4 -0.2 -0.2 -0.2 -0.2 -0.1 -0.1 -0.7 -0.2 -0.5 -0.5 -0.5 -0.5 -0.2 -0.3 -0.4 -0.2 -0.1 -0.4 -0.2 -0.1
Prospective memory result 0.6 0.8 3.1 -0.8 -1.1 -0.8 -0.4 0.2 -0.9 -1.2 -1.1 -1.8 0.0 -0.2 -1.1 0.5 0.9 -0.7 -1.0 0.2 -0.9 -0.2 1.3 0.3 -0.7 -1.2 -0.7 1.0 -0.8 -1.4 -0.7 -1.3 -1.1 0.5 -1.0 1.3 0.6 0.6 -0.9 -0.9 0.2 0.1 -0.8 -1.3 -0.1 -1.0 -0.6
Lung cancer (father) 1.9 2.2 3.9 1.7 1.5 1.5 1.5 1.2 1.8 1.4 1.5 1.2 1.9 1.9 1.4 1.2 1.3 1.6 1.0 1.7 1.5 1.8 -1.5 1.8 1.1 1.4 1.6 0.6 1.7 1.1 1.4 1.4 1.5 1.2 1.6 0.8 1.7 1.2 0.9 1.6 2.0 1.1 1.5 1.7 1.8 1.4 1.9
Illnesses of mother 4.3 5.3 16.3 1.6 2.2 2.6 3.2 3.7 0.8 1.9 2.0 0.7 0.8 0.4 2.2 1.9 2.9 2.8 1.6 2.4 2.4 2.7 -1.4 2.3 2.1 2.0 2.3 2.6 1.9 3.0 2.1 1.2 1.7 2.8 2.1 2.6 2.7 4.0 1.0 2.0 2.5 2.4 2.7 2.4 2.4 2.2 2.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 1.7 -0.1 -0.3 -0.4 -0.4 -0.5 0.2 -0.5 -0.4 -0.6 0.5 0.5 -0.2 -0.5 -1.1 -0.1 -0.2 0.0 -0.4 -0.4 -0.0 -0.4 -0.5 -0.4 -0.4 1.3 -0.2 -0.2 -0.4 -0.2 -0.3 -0.1 -0.2 0.4 0.0 -0.5 -0.2 -0.3 0.2 -0.1 -0.4 -0.4 -0.0 -0.4 -0.2
Pulse wave Arterial Stiffness index 0.7 0.9 2.6 0.8 1.2 1.2 1.2 0.7 0.5 1.2 1.1 0.7 0.1 -0.0 0.7 1.4 1.3 1.2 0.3 0.4 0.6 1.2 -1.5 0.9 0.7 1.0 1.6 1.1 0.8 1.6 0.5 1.0 1.0 0.6 1.1 0.5 0.3 0.5 0.4 0.9 1.0 0.2 1.1 0.8 0.6 1.0 0.8
Impedance of arm (left) 0.1 0.6 4.3 0.1 0.7 0.8 0.9 0.8 -0.7 0.5 0.6 0.3 -0.8 -1.0 0.5 -1.9 -0.9 0.8 0.5 -0.1 1.0 0.6 -0.3 0.1 0.2 0.6 0.3 -2.1 0.3 1.8 0.2 0.3 0.4 0.1 0.6 -0.3 0.1 1.1 -0.4 0.4 -0.2 0.3 0.7 1.0 0.2 0.6 0.7
Arm fat mass (right) 0.5 2.1 4.6 1.5 1.4 1.2 1.5 1.5 1.5 1.5 1.4 0.9 1.4 1.3 1.8 2.1 1.9 1.7 0.7 1.6 1.1 1.6 -2.0 1.6 1.7 1.3 1.4 1.8 1.5 1.1 1.4 1.4 1.3 1.5 1.4 0.2 1.3 1.1 1.4 1.3 2.0 0.0 1.5 1.0 1.5 1.5 0.9
Trunk predicted mass 0.7 4.2 10.2 2.5 2.0 1.8 1.5 1.1 2.7 2.0 2.0 1.8 3.2 3.1 2.0 1.8 2.2 1.9 2.3 2.4 1.4 2.0 -2.4 2.4 2.1 1.9 2.2 0.7 2.4 1.2 2.1 2.2 2.1 2.0 2.1 1.2 1.8 0.5 2.2 2.2 2.5 1.9 1.8 1.7 2.3 2.0 1.9
Standing height 0.7 7.3 12.4 3.3 3.0 2.9 2.4 1.5 2.9 3.1 3.0 2.7 3.2 2.9 2.6 0.9 1.5 2.9 3.5 2.5 2.4 2.8 -3.3 2.7 2.8 3.0 2.9 -0.5 3.3 3.0 2.8 3.3 3.2 2.0 3.2 0.7 1.9 0.8 2.4 3.1 2.6 2.4 2.8 3.0 2.8 3.0 2.9
Length of working week for main job 1.9 2.1 6.0 -1.6 -1.3 -1.2 -0.9 -0.8 -2.0 -1.4 -1.4 -1.6 -1.9 -1.9 -1.6 0.4 -1.0 -1.0 -1.6 -1.6 -1.9 -1.3 0.7 -1.7 -1.4 -1.6 -1.3 0.8 -1.6 -1.0 -1.8 -1.5 -1.6 -1.0 -1.4 -1.7 -1.2 -0.6 -2.0 -1.6 -1.2 -2.5 -1.2 -1.1 -1.5 -1.4 -1.6
Exposure to tobacco smoke at home 1.2 1.4 2.4 1.3 1.4 1.2 1.3 0.9 1.2 1.5 1.4 1.6 0.7 0.7 1.3 1.5 0.7 1.3 1.4 0.8 1.6 1.2 -1.4 0.9 1.0 1.4 1.3 0.2 1.2 1.5 1.1 1.4 1.4 0.6 1.4 -0.2 0.7 0.7 0.8 1.4 1.1 0.5 1.4 1.4 1.1 1.3 1.3
Breastfed as a baby 0.1 0.1 1.0 -0.1 -0.3 -0.2 -0.1 -0.2 -0.3 0.2 -0.2 -0.2 0.2 0.3 -0.4 -0.8 0.1 0.1 -0.4 0.0 -0.4 -0.3 0.0 0.1 -0.3 -0.3 -0.4 -0.3 -0.2 -0.2 -0.2 -0.2 -0.2 0.8 -0.2 1.0 0.1 -0.0 0.3 -0.1 0.0 0.6 -0.2 -0.6 0.0 -0.2 -0.2
Tense / ‘highly strung’ 0.7 1.2 3.2 -1.2 -1.2 -0.9 -0.7 -1.0 -1.4 -1.1 -1.1 -1.3 -1.2 -1.1 -1.3 -0.3 -0.2 -1.0 -1.3 -1.1 -1.2 -0.9 0.7 -1.0 -1.6 -1.3 -0.7 1.8 -1.3 -0.8 -1.5 -1.0 -1.3 -0.3 -1.2 0.1 -0.8 -0.4 -0.9 -1.2 -1.1 -1.3 -1.1 -1.7 -1.0 -1.3 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 2.5 3.8 7.7 -2.2 -2.2 -2.1 -2.1 -1.8 -2.1 -2.0 -2.1 -2.0 -1.9 -1.7 -1.9 -2.8 -2.2 -1.9 -2.2 -1.9 -1.9 -2.5 1.5 -2.4 -2.0 -2.2 -1.9 -1.5 -2.0 -1.8 -2.1 -2.1 -2.1 -1.4 -2.2 -0.3 -1.8 -1.4 -1.5 -2.2 -1.4 -1.3 -2.2 -1.9 -2.1 -2.0 -2.1
Hair/balding pattern: Pattern 4 0.8 1.9 9.9 -1.1 -1.3 -1.5 -1.8 -2.0 -0.8 -1.1 -1.3 -0.8 -0.5 -0.4 -1.4 -3.1 -1.0 -1.4 -1.2 -1.3 -1.2 -1.5 0.8 -1.4 -1.3 -1.3 -1.1 -1.0 -1.3 -1.4 -1.3 -1.1 -1.1 -1.5 -1.2 -0.5 -1.5 -2.3 -0.8 -1.2 -1.4 -1.0 -1.6 -1.8 -1.3 -1.4 -1.3
Birth weight of first child 0.2 0.4 1.7 -0.3 -0.7 -0.7 -0.8 -1.1 -0.1 -0.7 -0.6 -0.2 0.3 0.2 -0.7 -1.3 -0.1 -0.7 -0.3 -0.3 -0.7 -0.3 0.3 0.1 -0.8 -0.5 -0.8 0.4 -0.5 -0.6 -0.6 -0.3 -0.5 -0.4 -0.6 -0.2 -0.4 -1.0 0.1 -0.5 -0.8 -0.6 -0.7 -1.3 -0.3 -0.7 -0.6
Peak expiratory flow (PEF) 1.8 4.3 8.0 -2.2 -2.2 -2.2 -1.9 -1.7 -1.7 -2.5 -2.4 -2.2 -1.5 -1.4 -2.2 -0.3 -2.3 -2.2 -1.9 -1.6 -2.5 -2.2 2.4 -1.8 -2.8 -2.4 -2.5 0.5 -2.3 -2.2 -2.4 -2.3 -2.3 -1.8 -2.2 -1.7 -1.1 -1.1 -2.5 -2.2 -2.0 -2.1 -2.2 -1.8 -1.8 -2.6 -1.9
Pulse wave reflection index 1.8 2.3 5.5 1.4 1.7 1.8 1.9 1.2 0.9 1.6 1.6 1.3 0.7 0.4 1.5 1.7 2.1 1.7 0.9 1.1 1.6 1.9 -2.0 1.9 0.8 1.6 2.1 1.9 1.4 2.4 1.0 1.5 1.5 1.1 1.7 0.7 1.1 1.3 0.5 1.5 1.6 0.9 1.7 1.9 1.4 1.4 1.6
Ever highly irritable/argumentative for 2 days 1.5 1.7 4.2 -1.3 -1.6 -1.7 -1.4 -1.1 -0.8 -1.6 -1.6 -1.0 -0.6 -0.6 -1.6 -1.3 -0.8 -1.9 -2.0 -0.9 -1.2 -1.7 2.1 -0.1 -1.9 -1.5 -1.4 -0.4 -1.5 -1.8 -1.3 -1.4 -1.5 -1.2 -1.6 -0.3 -0.5 -0.6 -1.0 -1.3 -0.7 -1.0 -1.5 -1.2 -1.0 -1.7 -1.0
Loud music exposure frequency 1.0 1.1 2.3 -1.0 -1.0 -1.0 -0.8 -0.8 -1.5 -1.2 -1.1 -1.4 -0.8 -0.8 -1.0 0.9 -1.1 -0.8 -1.1 -0.9 -1.5 -0.5 0.2 -1.0 -1.2 -1.1 -1.1 -1.1 -1.1 -1.0 -1.3 -0.9 -1.1 -0.5 -1.0 -0.9 -0.7 -0.7 -1.2 -1.1 -1.2 -1.4 -1.0 -1.4 -0.9 -1.1 -1.4
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 4.0 -0.4 -0.6 -0.6 -0.2 0.2 -0.4 -0.6 -0.6 -1.1 0.0 -0.1 -0.1 -1.9 -1.0 -0.4 -0.5 0.1 -0.4 -0.2 0.3 -0.3 -0.4 -0.6 -0.5 -2.0 -0.5 -0.2 -0.4 -0.6 -0.7 -0.2 -0.6 -0.5 0.4 0.5 -0.8 -0.5 -0.2 -0.5 -0.4 -0.5 -0.1 -0.5 -0.5
Mouth/teeth dental problems: Bleeding gums 1.1 1.5 6.2 1.2 1.3 1.1 1.2 1.4 0.7 1.6 1.2 0.9 0.7 0.8 1.4 2.5 1.3 1.3 0.8 1.1 1.1 1.1 -1.7 1.5 1.8 1.3 0.8 0.5 1.3 1.4 1.4 1.3 1.1 0.9 1.2 0.1 0.8 0.7 1.0 1.2 1.7 0.2 1.3 1.0 1.1 1.5 1.1
Blood clot in the leg (DVT) 0.3 0.3 1.3 -0.8 -0.5 -0.5 -0.2 0.2 -0.9 -0.3 -0.5 -0.5 -1.0 -1.1 -0.3 -1.0 0.1 -0.4 0.0 -0.5 0.1 -0.4 1.1 0.0 -0.3 -0.3 -0.9 0.2 -0.5 -0.4 -0.3 -0.9 -0.6 -0.4 -0.6 -0.5 -0.3 0.6 -1.1 -0.6 -0.2 -0.3 -0.3 -0.1 -0.6 -0.4 -0.6
Medication: Paracetamol 0.1 0.2 1.8 -0.0 -0.2 -0.2 -0.6 -0.9 0.3 -0.1 -0.1 0.3 0.2 0.4 -0.5 1.3 -0.3 -0.4 -0.3 -0.3 -0.5 0.0 -0.1 -0.3 -0.1 -0.3 -0.2 0.6 -0.1 -0.7 -0.3 0.2 -0.0 -0.7 -0.1 -0.2 -0.6 -1.3 0.2 -0.2 -0.3 -0.5 -0.4 -0.3 -0.3 -0.2 -0.2
Headache pain in last month 0.4 0.7 2.9 -0.9 -0.7 -0.4 -0.1 -0.1 -1.7 -0.9 -0.9 -1.5 -0.9 -1.0 -1.1 0.5 -0.2 -0.4 -0.7 -0.5 -0.7 -0.3 0.7 -0.8 -1.0 -1.0 -0.6 0.3 -0.9 -0.7 -1.1 -1.1 -1.1 -0.3 -0.7 0.1 -0.1 0.3 -1.6 -0.9 -0.5 -0.7 -0.6 -0.9 -0.6 -0.9 -0.7
Medication for cholesterol, blood pressure or diabetes 1.5 2.5 5.2 1.6 1.6 1.6 1.6 1.5 1.5 1.7 1.6 1.2 1.4 1.2 1.6 0.6 2.1 1.7 2.3 1.5 1.8 1.4 -1.3 1.6 1.5 1.6 1.7 1.2 1.6 1.3 1.6 1.4 1.6 1.7 1.6 1.0 1.4 1.4 1.1 1.6 1.8 2.0 1.7 1.8 1.6 1.6 1.7
Glaucoma (self-reported) 0.9 1.1 4.2 -0.9 -1.2 -0.9 -0.5 -0.4 -1.2 -1.4 -1.3 -2.0 0.2 0.2 -1.4 0.7 -0.2 -0.8 -1.2 -0.1 -1.4 -0.8 1.0 -0.6 -1.5 -1.4 -0.8 2.0 -1.0 -1.4 -1.2 -1.3 -1.4 0.2 -1.1 0.9 0.4 0.1 -0.8 -1.1 -0.4 -0.4 -1.0 -1.6 -0.3 -1.4 -0.9
Gout (self-reported) 0.3 0.3 2.0 -0.2 -0.1 -0.3 -0.5 -0.8 -0.6 -0.1 -0.1 0.2 -0.4 -0.0 -0.0 -0.7 -0.8 -0.1 -0.4 -0.7 -0.7 0.0 -0.8 -0.9 -0.1 -0.1 0.1 -1.2 -0.3 -0.2 -0.4 0.2 -0.1 -0.7 -0.2 -1.4 -1.0 -1.2 -0.2 -0.3 -0.6 -1.4 -0.3 -0.6 -0.6 -0.1 -0.4
Hypothyroidism/myxoedema (self-reported) 5.0 9.7 16.5 -3.6 -3.3 -3.0 -2.8 -2.5 -4.1 -3.1 -3.3 -3.3 -3.7 -3.6 -3.1 -2.5 -1.8 -2.8 -3.4 -3.4 -3.3 -3.2 2.6 -2.9 -3.3 -3.3 -2.5 -0.6 -3.5 -2.5 -3.6 -3.4 -3.6 -2.2 -3.4 -1.4 -2.9 -1.8 -3.4 -3.5 -3.1 -3.4 -3.2 -3.7 -3.5 -3.3 -3.6
Medication: Amlodipine 1.3 1.8 4.1 -1.2 -1.3 -1.4 -1.7 -2.0 -0.9 -1.4 -1.2 -0.3 -1.1 -0.9 -1.1 -0.4 -1.7 -1.4 -1.5 -1.6 -1.4 -1.3 0.8 -1.2 -1.2 -1.1 -1.6 0.1 -1.2 -0.9 -1.4 -0.9 -1.0 -1.5 -1.3 -1.9 -1.8 -2.0 -0.7 -1.3 -1.7 -1.7 -1.5 -1.1 -1.6 -1.2 -1.5
Medication: Ventolin 100micrograms inhaler 1.5 1.9 4.0 1.3 1.3 1.4 1.6 1.9 1.3 1.2 1.3 0.5 1.2 1.2 1.2 2.0 1.5 1.6 0.9 1.7 1.3 1.3 -1.0 1.7 1.8 1.2 1.2 0.7 1.4 1.6 1.5 1.1 1.2 1.6 1.3 1.8 1.5 1.5 0.9 1.3 1.9 1.3 1.5 0.7 1.5 1.5 1.2
Birth weight 0.4 0.8 4.1 -0.4 -0.8 -0.9 -1.4 -1.8 -0.3 -0.8 -0.6 0.3 0.1 0.1 -0.9 -0.5 -1.2 -0.8 -0.2 -0.8 -1.0 -0.8 0.0 -1.0 -0.9 -0.7 -1.0 0.8 -0.5 -1.0 -0.8 -0.3 -0.4 -1.2 -0.6 -2.0 -1.1 -2.0 -0.5 -0.6 -1.2 -1.1 -1.0 -0.4 -0.8 -0.8 -0.8
Chronic bronchitis/emphysema (mother) 0.4 0.4 3.9 -0.4 -0.4 -0.7 -0.8 -0.8 -0.4 -0.1 -0.3 0.4 -0.7 -0.5 -0.2 -0.2 0.6 -0.9 0.2 -0.8 -0.2 -0.8 0.6 -0.1 -0.4 -0.2 -0.1 -0.7 -0.5 -0.4 -0.3 -0.0 -0.2 -1.3 -0.4 -2.0 -1.0 -1.1 -0.6 -0.4 -0.8 -1.1 -0.5 -0.4 -0.7 -0.4 -0.4
High blood pressure (siblings) 1.3 1.9 3.2 -1.5 -1.4 -1.5 -1.3 -1.2 -1.2 -1.3 -1.4 -1.1 -1.5 -1.5 -1.4 -0.9 -1.3 -1.3 -1.5 -1.5 -1.7 -1.3 1.0 -1.2 -1.5 -1.4 -1.5 -0.8 -1.5 -1.6 -1.6 -1.4 -1.5 -1.2 -1.4 -1.5 -1.2 -0.8 -1.2 -1.5 -1.4 -1.8 -1.4 -1.2 -1.5 -1.4 -1.4
Forced vital capacity (FVC), Best measure 0.0 0.2 1.5 0.0 -0.3 -0.2 -0.4 -0.4 0.3 -0.4 -0.3 -0.6 0.7 0.6 -0.2 -1.2 -0.9 -0.2 0.1 0.3 -0.1 -0.3 0.3 -0.3 -0.4 -0.3 -0.2 0.5 -0.0 -0.2 -0.1 -0.2 -0.2 -0.1 -0.1 0.9 0.3 -0.3 -0.1 -0.1 0.2 0.5 -0.3 -0.3 0.1 -0.3 0.1
Body fat percentage 0.2 0.9 6.0 0.8 0.9 0.7 0.9 0.9 0.8 0.9 0.9 0.7 0.5 0.5 1.3 2.5 1.1 1.1 -0.0 0.8 0.6 1.0 -1.2 0.9 1.3 0.9 0.8 1.5 0.9 0.9 0.8 0.9 0.8 0.7 0.8 -0.5 0.5 0.6 1.2 0.8 0.8 -0.6 0.9 0.6 0.8 1.1 0.4
Leg fat percentage (right) 0.1 0.5 7.8 0.2 0.1 -0.1 0.2 0.2 0.2 0.3 0.2 0.3 -0.0 0.0 0.5 2.5 1.1 0.3 -0.7 0.1 -0.1 0.4 -0.5 0.4 0.5 0.2 0.2 2.8 0.1 -0.1 0.1 0.3 0.1 0.2 0.0 -0.8 -0.0 0.0 0.7 0.1 0.2 -1.2 0.2 -0.2 0.1 0.3 -0.3
Arm fat-free mass (right) 0.2 0.8 3.5 1.1 0.6 0.4 0.2 0.0 1.4 0.7 0.6 0.7 1.9 1.9 0.7 1.8 1.3 0.5 0.8 1.1 0.1 0.5 -1.2 1.1 1.0 0.6 0.7 0.5 1.0 -0.1 0.8 1.0 0.8 0.7 0.7 0.2 0.6 -0.4 1.3 0.8 1.2 0.4 0.4 0.4 0.9 0.7 0.4
Exposure to tobacco smoke outside home 0.4 0.5 2.2 -0.9 -0.7 -0.7 -0.4 -0.0 -0.7 -0.8 -0.8 -1.1 -0.8 -1.0 -0.9 1.1 0.3 -0.6 -0.7 -0.4 -0.8 -0.9 0.9 -0.4 -0.9 -0.9 -0.3 0.1 -0.8 -1.1 -0.7 -1.1 -0.9 -0.3 -0.7 0.4 0.0 0.3 -1.5 -0.8 0.2 -0.4 -0.6 -0.4 -0.5 -0.9 -0.5
Comparative body size at age 10 0.5 1.4 5.0 -1.1 -1.5 -1.4 -1.0 -0.7 -0.8 -1.5 -1.4 -1.8 -0.4 -0.6 -0.8 -0.4 -0.6 -1.1 -1.6 -0.6 -1.6 -0.8 0.6 -1.3 -1.1 -1.5 -1.3 2.2 -1.1 -1.4 -1.2 -1.3 -1.4 -0.1 -1.4 0.2 -0.3 -0.2 -0.5 -1.3 -0.3 -1.1 -1.3 -1.7 -0.8 -1.2 -1.6
Number of full brothers 1.2 1.5 3.1 -1.2 -1.1 -0.9 -1.2 -1.5 -1.5 -1.1 -1.1 -0.9 -1.3 -1.3 -1.5 0.4 -1.3 -0.9 -1.5 -1.5 -1.5 -0.8 0.7 -1.4 -1.2 -1.1 -1.0 0.9 -1.3 -1.0 -1.6 -1.1 -1.1 -1.2 -1.1 -0.6 -1.6 -1.8 -0.8 -1.3 -1.7 -1.6 -1.2 -1.5 -1.4 -1.2 -1.2
Worry too long after embarrassment 0.5 0.8 4.0 -0.9 -0.6 -0.4 -0.5 -0.8 -1.4 -0.9 -0.7 -1.1 -1.3 -1.3 -0.8 -2.0 -0.8 -0.2 -1.0 -1.2 -1.1 -0.8 -0.4 -1.4 -0.7 -0.8 -0.5 -0.9 -0.8 -0.4 -1.2 -0.6 -0.9 -0.1 -0.6 0.4 -1.2 -0.7 -0.3 -1.0 -0.8 -0.6 -0.7 -1.0 -1.1 -0.6 -1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.3 2.0 -0.6 -0.4 -0.3 -0.5 -0.3 -0.9 -0.7 -0.3 -0.0 -1.1 -1.1 -0.6 -1.4 0.2 -0.5 -0.3 -0.8 0.0 -0.9 0.2 -0.5 -0.1 -0.3 -0.1 -1.1 -0.6 -0.2 -0.2 -0.3 -0.3 -0.8 -0.4 0.7 -0.9 -0.4 -0.4 -0.4 -0.2 0.1 -0.3 -0.5 -0.7 -0.3 -0.4
Wheeze or whistling in the chest in last year 0.2 0.3 1.4 0.2 0.4 0.3 0.1 -0.7 -0.0 0.4 0.5 0.5 -0.5 -0.4 0.1 1.2 -0.6 0.3 0.1 -0.6 -0.2 0.3 -1.2 -0.6 0.0 0.5 0.4 -1.0 0.1 0.5 -0.3 0.6 0.4 -0.3 0.4 -0.3 -0.9 -1.0 -0.2 0.2 0.2 -0.9 0.2 -0.5 -0.3 0.3 -0.3
Number of children fathered 0.5 0.6 4.4 0.3 -0.0 -0.4 -1.0 -1.8 1.0 0.0 0.1 1.2 0.6 0.9 -0.0 0.3 -1.0 -0.5 0.2 -0.6 -0.1 -0.3 -0.5 -0.6 -0.4 0.2 -0.2 -1.0 0.2 0.0 -0.2 0.7 0.4 -1.2 0.1 -1.8 -1.0 -2.1 0.9 0.1 -1.2 -0.4 -0.5 0.0 -0.4 -0.2 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 1.3 0.1 -0.1 -0.2 -0.5 -0.7 0.4 -0.1 -0.1 0.5 0.4 0.6 -0.3 0.7 -0.3 -0.3 0.1 -0.1 -0.0 -0.1 -0.2 -0.3 -0.1 -0.1 -0.3 1.1 -0.0 -0.3 -0.0 0.3 0.1 -0.3 -0.0 -0.0 -0.3 -0.9 0.6 -0.0 -0.4 0.2 -0.3 -0.1 -0.1 -0.1 -0.1
Age at first live birth 0.1 0.3 2.8 0.3 0.2 0.4 0.4 0.6 0.4 0.4 0.1 -0.5 0.6 0.6 0.3 -0.9 -0.2 0.3 0.4 0.6 0.1 0.1 -0.1 0.3 0.4 0.1 0.5 -0.5 0.3 0.3 0.4 0.1 0.1 0.9 0.2 1.7 0.7 0.7 0.6 0.3 0.3 1.0 0.3 -0.5 0.5 0.3 0.1
Pulse wave peak to peak time 0.6 0.7 2.3 -0.7 -1.1 -1.1 -1.2 -0.8 -0.3 -1.0 -1.0 -0.5 0.0 0.1 -0.7 -1.5 -1.3 -1.1 -0.1 -0.4 -0.5 -1.2 1.3 -0.8 -0.6 -0.9 -1.4 -1.1 -0.7 -1.5 -0.4 -0.9 -0.8 -0.7 -1.0 -0.6 -0.4 -0.7 -0.4 -0.8 -1.0 -0.1 -1.0 -0.7 -0.6 -0.9 -0.7
Health satisfaction 0.6 0.7 3.0 1.1 0.7 0.5 0.2 -0.4 1.6 0.8 0.9 1.6 1.4 1.7 0.6 1.1 0.3 0.3 0.7 0.6 0.3 0.5 -1.2 0.7 0.6 0.8 0.9 -0.1 0.8 0.5 0.7 1.5 1.1 0.0 0.8 -1.0 0.2 -0.9 1.3 1.0 0.1 -0.2 0.6 0.3 0.7 0.7 0.6
Shortness of breath walking on level ground 2.5 2.9 6.7 -1.6 -1.7 -2.0 -2.0 -2.0 -0.9 -1.8 -1.6 -1.0 -1.4 -1.3 -1.4 -0.5 -2.2 -1.9 -1.3 -1.9 -1.8 -1.8 1.3 -1.6 -1.7 -1.5 -2.0 -0.9 -1.7 -1.6 -1.7 -1.3 -1.5 -2.1 -1.8 -2.6 -1.8 -1.9 -1.3 -1.7 -2.1 -2.2 -1.8 -1.7 -1.8 -1.7 -1.8
Qualifications: College or University degree 0.7 2.2 4.2 -1.5 -1.7 -1.6 -1.6 -1.6 -1.3 -1.8 -1.7 -1.9 -0.9 -0.8 -1.6 -1.6 -1.7 -1.4 -0.9 -1.3 -2.0 -1.4 0.3 -1.9 -1.6 -1.6 -1.2 -0.1 -1.5 -1.9 -1.8 -1.2 -1.7 -0.6 -1.6 -0.4 -1.2 -1.3 -1.2 -1.7 -1.4 -0.9 -1.8 -2.0 -1.4 -1.6 -2.1
Eye problems/disorders: None of the above 0.7 0.8 2.7 0.5 0.8 1.0 1.2 1.5 0.4 0.9 0.7 0.3 -0.0 0.0 0.9 1.2 1.5 1.1 0.9 0.8 1.0 1.4 -1.0 0.8 1.1 0.8 0.8 -0.5 0.8 1.0 0.8 0.4 0.6 1.1 0.7 0.7 0.8 1.6 0.3 0.7 1.0 0.8 1.0 1.1 0.7 1.0 0.6
Mouth/teeth dental problems: Loose teeth 0.4 0.4 2.0 -0.7 -0.3 -0.3 -0.2 -0.1 -1.2 0.2 -0.3 -0.3 -1.4 -1.4 -0.2 0.6 -0.3 -0.2 -0.9 -0.9 -0.6 -0.2 -0.3 -0.9 -0.0 -0.3 -0.4 -0.4 -0.5 -0.2 -0.5 -0.3 -0.4 -0.5 -0.4 -1.2 -0.9 -0.2 -1.0 -0.5 0.1 -1.4 -0.2 -0.1 -0.8 -0.1 -0.7
Emphysema/chronic bronchitis 0.6 0.6 2.3 0.6 0.8 0.9 0.8 0.9 0.4 0.8 0.7 0.2 0.2 0.3 0.7 0.8 -0.4 0.9 0.6 0.6 0.3 0.7 -0.9 0.3 1.1 0.7 0.5 -1.5 0.8 0.7 0.8 0.6 0.7 0.9 0.8 1.5 0.4 0.7 0.6 0.6 1.4 1.4 0.8 0.7 0.6 0.9 0.8
Medication for pain relief, constipation, heartburn 0.1 0.2 1.2 0.2 -0.1 0.1 0.3 0.4 -0.1 -0.3 -0.1 -0.7 0.9 0.8 -0.1 -0.9 0.6 0.3 0.3 0.8 -0.2 0.2 -0.1 0.3 -0.1 -0.1 0.5 -0.7 0.1 -0.1 0.1 -0.1 -0.1 1.1 0.0 1.1 0.9 0.7 0.1 0.1 0.4 0.9 0.1 -0.3 0.6 -0.1 0.1
Neck or shoulder pain in last month 1.7 2.4 4.5 -1.6 -1.6 -1.3 -1.3 -1.5 -2.1 -1.7 -1.7 -1.8 -1.5 -1.4 -2.1 0.3 -1.1 -1.2 -1.5 -1.5 -1.2 -1.2 1.1 -1.5 -2.0 -1.8 -1.6 1.1 -1.7 -1.8 -2.0 -1.8 -1.8 -0.9 -1.5 0.2 -1.1 -1.0 -1.9 -1.7 -1.6 -1.2 -1.6 -1.9 -1.5 -1.8 -1.7
Medication: Blood pressure 1.3 2.3 4.8 -1.4 -1.6 -1.6 -1.7 -1.7 -1.2 -1.6 -1.5 -0.8 -1.1 -0.9 -1.5 -0.8 -2.2 -1.7 -1.9 -1.5 -1.7 -1.3 1.2 -1.4 -1.6 -1.5 -1.9 -1.8 -1.5 -1.6 -1.5 -1.2 -1.4 -1.6 -1.5 -1.4 -1.4 -1.6 -1.0 -1.5 -1.7 -1.8 -1.6 -1.4 -1.5 -1.6 -1.4
Angina (self-reported) 0.7 0.9 4.4 -0.6 -0.4 -0.7 -1.0 -1.5 -0.9 -0.2 -0.3 0.3 -1.2 -1.2 -0.2 -1.2 -1.5 -0.6 -0.6 -1.5 -0.3 -0.4 -0.5 -1.1 -0.7 -0.2 -0.6 -1.3 -0.7 -0.2 -0.9 0.0 -0.3 -1.5 -0.5 -2.1 -1.8 -1.6 -0.5 -0.6 -1.0 -1.5 -0.7 -0.5 -1.2 -0.5 -0.7
Migraine (self-reported) 0.4 0.5 6.4 0.5 0.4 0.6 0.7 0.9 0.1 0.8 0.4 -0.1 0.6 0.5 0.4 1.1 1.5 0.6 0.9 0.7 0.5 0.6 0.0 0.7 0.4 0.3 0.6 2.5 0.4 0.4 0.5 0.2 0.4 0.7 0.5 0.8 0.9 1.0 -0.2 0.5 0.6 0.5 0.6 0.2 0.7 0.4 0.6
Medication: Ibuprofen 0.4 0.5 1.2 0.8 0.7 0.6 0.3 -0.0 1.0 1.0 0.8 0.8 0.7 1.1 1.0 0.1 -0.4 0.5 1.1 0.4 0.8 0.5 -1.0 0.2 0.6 0.7 0.6 -0.9 0.9 0.5 0.6 0.9 0.8 0.2 0.8 0.2 0.1 -0.2 1.0 0.7 0.2 0.9 0.5 0.5 0.5 0.7 0.6
Medication: Allopurinol 0.3 0.3 1.9 -0.2 -0.1 -0.3 -0.6 -1.1 -0.5 -0.2 -0.1 0.4 -0.4 -0.1 -0.1 -0.7 -0.5 -0.2 -0.5 -0.8 -0.4 0.2 -0.5 -0.6 -0.3 0.0 0.1 -0.9 -0.2 -0.0 -0.4 0.2 -0.1 -0.9 -0.1 -1.2 -1.1 -1.4 -0.0 -0.2 -0.7 -1.3 -0.4 -0.6 -0.7 -0.2 -0.2
Medication: Omeprazole 1.2 1.4 3.0 -1.3 -1.2 -1.3 -1.0 -1.1 -1.7 -1.2 -1.2 -1.2 -1.3 -1.3 -1.1 -0.9 -1.5 -0.9 -1.4 -1.3 -0.8 -0.9 1.0 -1.2 -1.5 -1.2 -1.7 -0.5 -1.3 -1.6 -1.3 -1.4 -1.2 -0.9 -1.2 -0.8 -1.0 -0.6 -1.5 -1.2 -0.9 -1.0 -1.2 -0.8 -1.2 -1.3 -1.1
Medication: Seretide 50 evohaler 1.3 1.5 3.5 -1.6 -1.3 -1.1 -1.0 -0.6 -1.5 -1.4 -1.3 -1.4 -1.9 -1.8 -1.5 0.2 -0.7 -1.3 -1.4 -1.2 -1.1 -1.1 1.3 -1.1 -1.0 -1.3 -1.6 0.6 -1.4 -1.0 -1.2 -1.5 -1.4 -1.2 -1.3 -0.2 -1.1 -0.3 -1.5 -1.4 -1.0 -0.9 -1.2 -1.0 -1.4 -1.2 -1.2
Mean time to correctly identify matches 0.3 0.6 2.2 0.8 0.8 0.8 0.8 0.7 0.6 0.7 0.8 0.4 0.7 0.7 0.7 0.7 0.7 1.0 0.5 0.7 0.9 1.0 -0.9 0.5 0.9 0.7 0.6 0.2 0.9 0.4 0.8 0.7 0.7 0.9 0.9 1.5 0.6 0.6 1.0 0.8 1.2 1.2 0.8 0.7 0.7 0.8 0.7
Heart disease (mother) 5.7 6.9 13.2 -2.4 -2.7 -2.9 -3.1 -3.6 -1.9 -2.1 -2.6 -1.8 -1.7 -1.5 -2.6 -2.8 -2.7 -2.8 -2.4 -2.9 -2.4 -2.9 2.0 -2.6 -3.3 -2.6 -2.4 -2.8 -2.7 -3.0 -3.0 -2.2 -2.4 -2.7 -2.6 -2.4 -2.6 -3.1 -2.3 -2.6 -2.6 -2.7 -3.0 -2.6 -2.7 -2.9 -2.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 2.2 0.4 0.7 0.6 0.9 1.2 0.7 0.4 0.6 0.5 0.1 -0.1 1.0 0.1 1.2 0.7 0.4 0.6 1.0 0.5 -0.2 0.9 0.8 0.7 0.4 1.5 0.7 1.0 0.8 0.3 0.5 0.6 0.6 1.0 0.7 1.5 0.9 0.6 0.9 0.9 0.8 1.2 0.6 0.8 0.7
Whole body fat mass 0.3 1.4 6.1 1.2 1.1 1.0 1.2 1.1 1.3 1.2 1.1 0.8 1.1 1.0 1.4 2.5 1.5 1.3 0.4 1.2 0.8 1.3 -1.7 1.4 1.5 1.1 1.1 1.5 1.2 1.0 1.1 1.2 1.1 1.1 1.1 -0.1 0.9 0.7 1.4 1.1 1.3 -0.3 1.2 0.8 1.2 1.3 0.7
Leg fat mass (right) 0.2 0.8 6.5 0.8 0.7 0.5 0.7 0.7 1.0 0.9 0.7 0.6 0.8 0.8 1.0 2.5 1.6 0.9 -0.0 0.8 0.2 0.9 -1.2 0.9 1.1 0.7 0.7 2.2 0.8 0.4 0.7 0.8 0.7 0.8 0.6 -0.4 0.5 0.3 1.2 0.7 1.0 -0.7 0.7 0.3 0.7 0.9 0.2
Arm predicted mass (right) 0.2 1.2 4.8 1.3 0.7 0.6 0.5 0.3 1.7 0.8 0.8 0.7 2.2 2.1 0.9 2.0 1.5 0.7 1.0 1.5 0.4 0.8 -1.2 1.4 1.2 0.8 0.9 0.7 1.2 0.1 1.1 1.1 0.9 1.0 0.9 0.6 1.0 -0.1 1.4 1.0 1.5 0.8 0.7 0.6 1.2 0.9 0.7
Pulse rate, automated reading 1.3 4.3 8.4 -1.9 -2.1 -2.5 -2.7 -2.7 -1.2 -1.9 -2.0 -1.1 -1.4 -1.3 -2.2 -1.6 -2.0 -2.5 -2.0 -2.2 -2.1 -2.4 1.9 -2.0 -1.9 -1.9 -2.2 -0.6 -2.1 -2.3 -1.9 -1.6 -1.8 -2.4 -2.1 -2.3 -2.3 -2.9 -1.3 -2.0 -2.5 -2.4 -2.3 -2.3 -2.2 -2.1 -2.2
Alcohol intake frequency. 0.3 0.6 2.4 -1.0 -0.6 -0.4 -0.1 0.5 -1.6 -0.9 -0.7 -1.1 -1.3 -1.3 -0.6 0.2 0.8 -0.5 -1.0 -0.4 0.1 -0.6 1.3 -0.3 -0.4 -0.6 -0.7 0.8 -0.7 -0.7 -0.4 -1.1 -0.8 -0.4 -0.6 1.4 -0.1 0.9 -1.4 -0.7 0.6 0.1 -0.4 -0.2 -0.6 -0.5 -0.3
Comparative height size at age 10 1.1 6.0 8.7 2.7 2.8 2.7 2.6 1.9 2.1 2.8 2.7 1.9 2.3 1.8 2.8 1.8 2.2 2.7 2.9 2.2 2.1 2.8 -2.6 2.6 2.7 2.7 2.7 1.3 3.0 2.8 2.4 2.7 2.7 2.0 2.9 1.0 1.8 1.6 1.8 2.6 3.0 2.0 2.6 2.8 2.4 2.8 2.4
Number of full sisters 0.2 0.2 1.4 0.1 -0.3 -0.2 -0.3 -0.8 -0.0 -0.3 -0.2 -0.4 0.5 0.5 -0.5 1.2 -0.4 -0.0 0.1 -0.1 -0.7 -0.1 -0.7 -0.0 -0.4 -0.3 -0.1 1.0 -0.2 -0.4 -0.4 0.1 -0.2 0.4 -0.2 -0.1 -0.2 -0.9 -0.1 -0.2 -0.4 -0.5 -0.3 -1.1 -0.1 -0.3 -0.7
Suffer from ‘nerves’ 1.3 2.0 4.2 -1.6 -1.3 -1.2 -1.2 -1.2 -1.7 -1.1 -1.4 -1.7 -2.0 -2.0 -1.4 -0.9 -1.1 -1.0 -1.9 -1.8 -1.9 -1.5 0.3 -1.6 -1.4 -1.4 -1.0 0.9 -1.5 -0.6 -1.8 -1.3 -1.6 -0.9 -1.4 -0.3 -1.7 -1.0 -1.4 -1.6 -0.9 -1.9 -1.4 -1.7 -1.7 -1.3 -1.6
Overall health rating 0.1 0.3 1.6 -0.5 -0.4 -0.5 -0.3 -0.4 -0.6 -0.6 -0.3 -0.0 -1.0 -1.0 -0.3 0.7 -0.5 -0.4 -0.8 -0.7 -0.3 -0.5 -0.2 -0.3 -0.6 -0.3 -0.4 0.5 -0.6 -0.2 -0.6 -0.2 -0.4 -0.5 -0.5 -1.2 -0.7 -0.3 -0.5 -0.4 -0.4 -1.2 -0.3 -0.4 -0.6 -0.4 -0.6
Chest pain or discomfort 0.7 1.1 2.3 -1.2 -1.0 -1.0 -0.9 -0.7 -1.2 -1.3 -1.0 -1.0 -1.5 -1.4 -1.0 -0.4 -1.4 -0.9 -0.8 -1.2 -1.0 -1.1 0.4 -1.5 -0.7 -0.9 -1.0 -0.8 -1.1 -0.8 -1.0 -1.0 -1.1 -1.0 -1.1 -0.4 -1.2 -0.7 -1.0 -1.1 -1.0 -0.8 -1.0 -1.2 -1.2 -0.9 -1.3
Had major operations 0.1 0.2 1.4 -0.1 0.3 0.3 0.4 0.4 -0.3 0.5 0.4 0.6 -0.9 -1.2 0.2 0.3 0.1 0.3 0.0 -0.3 0.8 0.2 0.2 0.2 -0.1 0.4 0.3 0.1 -0.1 1.0 0.1 -0.0 0.3 0.1 0.2 -0.1 -0.1 0.6 -0.2 0.2 -0.3 0.0 0.4 0.6 -0.1 0.2 0.3
Age at last live birth 1.1 1.6 5.1 1.4 1.2 1.2 0.9 0.8 1.7 1.7 1.2 0.9 1.4 1.7 1.4 -0.4 -0.3 1.1 1.3 1.2 1.3 1.0 -1.1 1.0 1.4 1.2 1.2 -0.7 1.4 1.4 1.4 1.4 1.3 1.1 1.2 2.2 0.9 0.5 1.9 1.3 1.1 2.0 1.1 0.1 1.2 1.3 1.2
Family relationship satisfaction 0.4 0.4 1.3 -0.7 -0.8 -0.9 -0.9 -0.6 -0.3 -1.1 -0.8 -0.6 -0.4 -0.3 -0.6 -0.2 -0.5 -1.0 -1.0 -0.4 -0.2 -1.0 0.7 -0.4 -0.6 -0.7 -0.9 -0.8 -0.7 -0.9 -0.5 -0.7 -0.7 -0.9 -0.8 -0.2 -0.5 -0.5 -0.5 -0.7 -0.0 -0.0 -0.8 -0.2 -0.6 -0.7 -0.5
Leg pain on walking 1.4 1.7 6.7 -1.4 -1.2 -1.3 -0.8 -0.6 -1.5 -1.2 -1.3 -1.6 -1.5 -1.6 -1.2 0.9 -0.2 -0.9 -1.2 -1.1 -1.5 -0.7 0.4 -1.1 -1.2 -1.3 -1.2 0.6 -1.4 -1.1 -1.5 -1.3 -1.5 -1.2 -1.3 -2.1 -0.8 -0.3 -2.3 -1.4 -0.9 -2.6 -1.1 -1.4 -1.2 -1.3 -1.4
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.5 3.0 -0.5 -0.3 -0.6 -0.7 -1.1 -0.3 -0.5 -0.3 0.2 -0.8 -0.8 -0.3 0.2 -0.5 -0.5 -0.4 -1.1 -1.0 -0.5 -0.1 -0.5 -0.6 -0.3 -0.5 0.5 -0.6 -0.2 -0.8 -0.3 -0.4 -1.1 -0.4 -1.6 -1.2 -1.5 -0.3 -0.5 -0.9 -1.7 -0.6 -0.6 -0.9 -0.5 -0.7
Commuting to job workplace: Car/motor vehicle 2.8 3.2 9.4 2.0 1.9 1.6 1.1 0.9 3.1 1.7 2.0 2.8 1.8 2.0 1.8 0.4 1.3 1.1 2.1 1.5 2.3 1.4 -0.9 1.6 2.0 2.2 1.9 0.4 2.0 1.8 2.3 2.1 2.3 0.2 1.9 0.2 0.9 0.2 2.1 2.1 0.9 2.1 1.7 2.3 1.6 1.9 2.1
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 5.4 0.3 0.2 0.3 0.1 -0.2 -0.1 -0.2 0.2 -0.0 0.5 0.6 -0.2 0.2 1.0 0.6 0.1 0.2 -0.2 0.4 -0.4 0.1 -0.0 0.2 0.6 2.3 0.2 0.4 -0.1 0.2 0.1 0.7 0.2 0.3 0.2 -0.3 0.5 0.2 -0.5 -0.1 0.1 -0.4 0.3 0.1 0.0
Medication: Aspirin 0.1 0.1 1.5 0.0 -0.1 -0.2 -0.1 0.3 0.1 -0.3 -0.1 0.2 0.4 0.2 -0.0 1.2 -0.1 -0.5 -0.8 0.4 0.0 -0.1 0.5 0.2 -0.0 -0.1 -0.4 0.5 -0.1 -0.4 0.2 0.0 -0.0 -0.4 -0.1 -0.3 0.5 0.3 0.1 0.0 0.2 -0.2 -0.0 0.3 0.2 -0.1 0.4
Supplements: Vitamin C 0.5 0.6 3.2 0.3 0.5 0.9 1.2 1.5 -0.0 0.3 0.4 -0.1 -0.0 -0.2 0.1 1.1 1.4 0.9 0.1 0.8 0.5 0.8 0.0 0.9 0.6 0.2 0.5 1.5 0.3 0.6 0.5 -0.1 0.2 1.2 0.5 0.8 1.1 1.8 -0.4 0.4 0.6 0.2 0.8 0.8 0.7 0.5 0.6
Knee pain experienced in last month 0.3 0.4 1.0 0.8 0.8 0.6 0.3 0.1 0.7 0.4 0.8 0.8 0.8 0.8 0.6 1.0 0.4 0.4 0.8 0.5 0.8 0.3 -0.6 0.5 0.7 0.7 0.6 0.1 0.8 0.7 0.7 1.0 0.8 -0.3 0.8 -0.4 0.2 -0.1 0.2 0.7 0.9 0.2 0.6 0.9 0.6 0.7 0.7
Hypertension (Self-reported) 0.2 0.6 2.8 -0.4 -0.6 -0.8 -0.9 -1.1 -0.2 -1.0 -0.5 0.2 -0.3 -0.1 -0.4 0.3 -0.8 -0.6 -1.2 -0.8 -1.0 -0.6 -0.5 -0.8 -0.3 -0.4 -0.5 1.2 -0.5 -0.5 -0.6 0.0 -0.4 -0.8 -0.6 -1.4 -1.1 -1.4 0.4 -0.6 -0.8 -1.7 -0.7 -0.8 -0.8 -0.4 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 1.5 -0.9 -0.9 -0.9 -1.0 -1.1 -0.7 -0.9 -0.9 -1.0 -0.9 -0.7 -1.1 -1.2 -0.8 -1.0 -0.4 -1.0 -0.6 -1.1 0.6 -1.2 -0.9 -0.9 -0.8 0.5 -0.9 -1.0 -1.0 -0.9 -0.9 -1.2 -0.8 -0.6 -1.0 -0.8 -1.0 -1.0 -1.0 -0.6 -1.0 -0.9 -1.0 -0.9 -1.0
Illnesses of father: Heart disease 9.5 13.2 18.8 -3.8 -4.1 -4.0 -4.0 -3.8 -3.4 -4.1 -4.0 -3.5 -2.9 -2.8 -4.0 -3.2 -3.0 -3.6 -3.8 -3.5 -4.0 -3.9 2.5 -3.4 -4.0 -4.0 -3.5 -1.2 -4.0 -4.3 -4.1 -3.6 -4.0 -2.4 -4.1 -1.7 -3.1 -3.2 -2.7 -4.0 -3.8 -3.3 -4.2 -4.3 -3.7 -4.1 -4.3
Illnesses of siblings: Diabetes 1.5 1.8 3.3 -1.6 -1.4 -1.2 -0.9 -0.7 -1.6 -1.3 -1.4 -1.6 -1.7 -1.8 -1.3 -0.5 -0.4 -1.2 -1.5 -1.3 -1.6 -1.2 0.9 -1.3 -1.3 -1.5 -0.9 -0.9 -1.6 -0.9 -1.6 -1.4 -1.6 -0.8 -1.5 -1.1 -1.0 -0.4 -1.3 -1.5 -1.8 -1.8 -1.2 -1.7 -1.4 -1.4 -1.8
Smoking status: Previous 0.3 0.5 1.2 0.9 0.6 0.3 0.5 0.1 0.9 0.3 0.7 0.9 1.1 1.1 1.0 0.9 -0.1 0.7 0.2 0.7 0.7 0.7 -0.5 0.8 0.2 0.7 0.4 0.9 0.8 0.7 0.6 0.8 0.8 0.8 0.5 -0.6 0.7 0.2 1.0 0.8 0.4 -0.0 0.6 0.4 0.8 0.5 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 1.5 0.9 0.9 0.9 0.9 0.8 0.9 1.0 0.8 0.3 1.0 0.8 0.8 1.0 0.7 1.1 1.0 0.9 0.7 0.8 -1.2 1.1 0.7 0.8 1.1 0.3 1.0 1.1 0.8 0.7 0.7 1.1 0.9 1.1 1.0 0.9 0.3 0.8 1.2 1.0 0.9 0.8 1.0 0.8 0.9
Whole body fat-free mass 0.6 3.6 8.0 2.3 1.8 1.7 1.5 1.1 2.4 1.9 1.8 1.5 2.8 2.7 1.9 1.7 2.1 1.9 2.0 2.2 1.2 1.9 -2.4 2.2 2.0 1.8 1.9 0.5 2.2 1.2 1.9 2.0 1.9 1.9 2.0 1.2 1.7 0.6 2.0 2.0 2.5 1.5 1.7 1.5 2.1 1.9 1.7
Leg fat-free mass (right) 0.5 2.7 6.2 1.9 1.6 1.6 1.6 1.3 1.7 1.8 1.6 0.9 2.2 2.0 1.8 1.4 1.9 1.8 1.6 2.0 1.0 1.8 -2.5 2.0 1.9 1.5 1.7 0.2 1.9 1.3 1.6 1.7 1.6 1.8 1.7 1.1 1.5 0.9 1.6 1.6 2.3 0.9 1.6 1.1 1.8 1.7 1.3
Arm fat percentage (left) 0.2 0.7 2.7 0.7 0.8 0.6 0.9 1.0 0.7 0.8 0.8 0.4 0.4 0.5 1.3 1.6 1.2 1.1 0.0 0.8 0.6 0.9 -1.4 0.9 1.2 0.8 0.7 0.9 0.8 0.8 0.7 0.7 0.7 0.8 0.7 -0.4 0.6 0.7 0.8 0.7 1.1 -0.6 0.9 0.5 0.7 1.0 0.3
Average weekly red wine intake 0.2 0.3 1.8 0.4 0.1 0.1 0.4 0.5 0.8 -0.0 0.1 -0.3 1.0 1.0 0.5 0.4 0.2 0.6 -0.0 0.8 -0.1 0.0 -0.4 0.3 0.3 0.0 0.7 1.0 0.4 0.4 0.3 0.2 0.1 1.4 0.1 0.6 0.9 0.5 0.9 0.2 0.6 0.3 0.2 0.1 0.6 0.2 -0.0
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.7 0.8 0.4 0.3 0.5 0.4 1.0 0.1 0.5 0.5 1.3 1.3 0.5 0.4 0.8 0.5 0.9 1.0 0.5 0.7 -0.7 0.8 0.4 0.4 0.7 -0.2 0.7 0.7 0.7 0.7 0.6 0.5 0.5 -0.5 1.0 0.4 0.9 0.7 0.3 0.1 0.5 0.5 0.9 0.4 0.6
Mood swings 0.3 0.6 2.2 0.3 0.8 0.7 0.3 -0.0 0.3 0.9 0.9 1.3 -0.8 -0.7 1.0 -1.3 0.6 0.3 0.4 -0.7 0.7 0.3 -1.1 0.1 0.9 0.9 0.9 1.1 0.4 1.4 0.4 1.0 0.7 -0.2 0.6 -0.0 -1.1 -0.4 1.5 0.5 -0.1 -0.1 0.6 0.2 -0.3 0.9 0.1
Loneliness, isolation 0.1 0.2 2.0 -0.1 0.1 0.3 0.1 -0.1 -0.5 0.1 0.1 -0.2 -0.6 -0.6 -0.1 -0.1 0.6 0.2 -0.5 -0.4 -0.3 -0.2 -0.9 -0.4 0.2 0.0 0.5 0.7 0.0 0.3 -0.3 0.1 -0.1 0.3 0.1 1.4 -0.6 -0.2 0.2 -0.1 0.8 0.2 0.0 -0.3 -0.3 0.2 -0.2
Long-standing illness, disability or infirmity 1.4 2.2 5.5 -1.6 -1.3 -1.4 -1.4 -1.1 -1.8 -1.3 -1.2 -0.7 -2.1 -2.1 -1.4 -2.4 -1.9 -1.6 -1.6 -1.8 -1.0 -1.6 1.2 -1.7 -1.2 -1.2 -1.8 -1.4 -1.6 -1.4 -1.3 -1.2 -1.3 -1.8 -1.4 -0.7 -1.8 -1.1 -1.6 -1.4 -1.0 -1.2 -1.3 -1.2 -1.7 -1.3 -1.3
Ever had bowel cancer screening 0.6 0.7 5.8 0.5 0.6 0.8 0.9 0.8 0.4 0.7 0.7 0.2 0.1 -0.2 0.5 0.7 1.4 1.2 0.5 0.4 0.4 0.5 -0.6 0.8 0.8 0.6 0.9 2.4 0.5 0.8 0.5 0.4 0.6 1.7 0.6 1.6 0.4 0.7 0.9 0.6 1.1 0.8 0.8 0.3 0.5 0.8 0.3
Diabetes diagnosed by doctor 1.6 2.7 4.4 -1.8 -1.6 -1.7 -1.6 -1.2 -1.7 -1.4 -1.7 -1.5 -1.8 -1.9 -1.5 -1.4 -1.6 -1.6 -2.0 -1.7 -1.6 -1.8 1.4 -1.8 -1.4 -1.7 -2.1 -1.2 -1.7 -1.3 -1.6 -1.7 -1.7 -1.8 -1.7 -1.4 -1.5 -1.0 -1.6 -1.8 -1.4 -2.0 -1.7 -1.2 -1.8 -1.6 -1.8
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 5.3 -1.2 -0.7 -0.8 -0.7 -0.6 -1.5 -0.8 -0.8 -0.9 -1.9 -2.3 -0.9 -1.0 -0.7 -0.7 -1.1 -1.6 -1.1 -0.9 0.9 -1.0 -0.9 -0.8 -0.9 0.0 -1.1 -0.3 -1.1 -1.0 -1.0 -1.0 -0.9 -0.7 -1.3 -0.6 -1.6 -1.0 -0.8 -1.3 -0.7 -1.0 -1.3 -0.9 -0.9
Friendships satisfaction 5.2 6.4 10.1 -2.8 -3.0 -3.1 -2.9 -2.2 -2.2 -3.1 -2.9 -2.3 -2.0 -1.7 -2.6 -2.1 -1.8 -3.2 -2.7 -2.2 -2.2 -3.1 2.8 -1.9 -2.5 -2.9 -2.7 -2.3 -2.8 -2.9 -2.4 -2.6 -2.8 -2.9 -2.9 -1.9 -1.9 -1.8 -2.1 -2.8 -2.3 -2.0 -2.9 -2.0 -2.5 -2.8 -2.5
Qualifications: nursing, teaching 1.1 1.7 3.6 -1.2 -1.7 -1.5 -1.4 -1.0 -1.0 -1.9 -1.8 -1.6 -0.0 0.1 -1.7 -1.0 -0.9 -1.4 -1.8 -0.4 -1.7 -1.1 1.5 -1.0 -1.6 -1.7 -1.5 1.3 -1.3 -1.7 -1.3 -1.6 -1.6 -0.5 -1.6 -0.4 -0.1 -0.7 -1.2 -1.4 -1.4 -0.7 -1.6 -1.2 -0.8 -1.7 -1.2
Commuting to job workplace: Walk 0.5 0.6 1.6 -0.8 -1.0 -1.1 -0.7 -0.6 -0.6 -0.7 -1.0 -1.0 -0.2 -0.2 -0.7 -0.5 0.0 -0.9 -1.3 -0.5 -0.9 -0.5 0.4 -0.5 -0.7 -0.9 -0.8 -0.5 -0.7 -1.2 -0.8 -0.7 -1.0 -0.4 -1.0 -0.2 -0.3 -0.3 -0.2 -0.9 -0.3 -0.7 -0.9 -1.1 -0.6 -0.8 -1.0
Eye problems/disorders: Cataract 1.1 1.3 2.9 -1.1 -1.1 -1.1 -1.2 -1.3 -1.1 -1.3 -1.0 -0.6 -1.1 -1.2 -1.2 -1.5 -1.6 -1.4 -1.0 -1.3 -0.8 -1.6 1.7 -1.0 -1.3 -1.1 -1.1 0.1 -1.2 -1.3 -1.1 -1.0 -1.0 -1.2 -1.1 -0.4 -1.1 -1.1 -0.8 -1.0 -1.4 -0.6 -1.2 -1.2 -1.2 -1.2 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 1.3 0.5 0.4 0.1 -0.1 -0.6 0.8 0.5 0.4 0.5 0.4 0.5 0.3 1.2 -0.3 0.4 0.4 -0.1 0.3 -0.1 -1.1 -0.0 0.0 0.4 0.4 0.6 0.3 0.4 0.0 0.7 0.5 0.2 0.3 -0.8 -0.4 -0.8 0.3 0.3 0.1 -0.4 0.1 -0.1 0.1 0.3 -0.0
Medication for cholesterol 0.4 0.6 6.1 -0.8 -0.7 -0.4 -0.2 0.5 -0.8 -0.5 -0.8 -1.0 -0.6 -0.6 -0.8 -0.9 -1.3 -0.6 -0.4 -0.1 -0.5 -0.3 1.8 -0.6 -0.4 -0.8 -1.2 -2.5 -0.7 -0.7 -0.3 -1.3 -0.8 -0.2 -0.7 0.1 0.3 0.7 -1.3 -0.6 -0.4 0.2 -0.4 0.1 -0.3 -0.7 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.4 0.1 0.0 -0.0 -0.2 -0.3 0.1 0.4 0.2 0.6 -0.1 -0.1 0.1 0.1 0.1 -0.3 0.2 -0.3 0.2 -0.4 0.3 0.3 0.2 0.2 -0.1 0.5 0.1 0.2 0.2 0.3 0.2 -0.4 0.0 -0.2 -0.4 -0.3 0.6 0.1 -0.0 0.0 -0.0 0.2 -0.2 0.2 -0.0
Back pain experienced in last month 0.3 0.4 1.3 0.5 0.8 0.8 0.8 0.8 0.7 0.6 0.7 0.9 0.1 0.1 0.4 0.9 -0.6 0.5 0.6 0.5 0.7 0.5 -0.1 0.2 0.5 0.6 0.2 0.2 0.5 0.5 0.7 0.4 0.7 0.1 0.8 0.6 0.6 0.7 -0.0 0.7 0.7 0.8 0.8 1.1 0.6 0.6 0.9
Mineral and other dietary supplements 0.1 0.1 0.7 0.2 0.3 0.2 0.3 0.2 0.4 0.5 0.3 0.2 -0.0 -0.1 0.5 -0.3 0.4 0.2 0.3 0.1 0.8 0.2 -0.5 0.4 0.3 0.4 0.3 -0.1 0.3 0.2 0.2 0.4 0.3 0.1 0.3 0.8 0.0 0.3 0.4 0.2 0.6 0.7 0.3 0.2 0.1 0.3 0.0
Breast cancer (self-reported) 0.7 0.9 2.6 1.2 1.2 1.0 0.5 -0.0 1.1 1.0 1.2 1.6 0.9 1.1 0.8 0.7 0.2 0.8 1.3 0.6 0.9 0.6 -0.9 0.6 0.9 1.1 1.0 -0.3 1.1 1.0 1.0 1.2 1.3 0.1 1.2 -0.5 0.1 -0.5 0.9 1.1 0.4 0.7 0.9 1.3 0.8 1.1 1.2
Asthma (self-reported) 0.1 0.3 4.0 -0.4 -0.2 -0.3 -0.6 -0.4 0.2 -0.3 -0.1 0.5 -0.7 -0.7 -0.6 -0.1 -0.6 -0.8 -0.2 -0.5 0.1 -0.4 1.0 -0.0 -0.1 -0.1 -0.5 -2.0 -0.4 -0.2 0.1 -0.2 -0.0 -1.0 -0.3 -0.3 -0.7 -0.6 -0.5 -0.2 -0.5 -0.1 -0.3 -0.0 -0.5 -0.2 -0.1
Osteoporosis (self-reported) 2.7 3.4 6.4 2.1 1.9 2.0 1.8 1.6 2.2 1.9 1.8 1.5 2.5 2.4 1.5 1.0 1.2 1.6 1.9 2.2 2.1 1.8 -1.2 2.0 1.2 1.7 1.7 -0.0 2.0 1.3 1.8 1.7 1.9 1.4 2.0 1.6 2.3 1.6 1.6 2.0 1.8 2.2 1.9 2.3 2.3 1.6 2.5
Osteoarthritis (self-reported) 0.1 0.2 2.5 0.2 0.0 -0.3 -0.5 -0.7 0.3 -0.3 0.1 0.4 0.5 0.5 0.1 1.6 -0.4 -0.4 0.1 -0.0 0.0 -0.3 0.1 -0.4 0.1 0.0 -0.0 0.5 0.2 -0.4 0.2 0.4 0.2 -0.7 0.0 -0.6 -0.3 -1.0 0.1 0.1 -0.0 -0.2 -0.2 -0.5 -0.1 0.0 0.1
Medication: Aspirin 0.1 0.2 1.1 -0.3 -0.4 -0.5 -0.5 -0.2 -0.1 -0.5 -0.3 0.0 0.0 -0.1 -0.2 0.8 -0.5 -0.7 -1.0 -0.1 -0.3 -0.4 0.6 -0.1 -0.2 -0.4 -0.7 0.1 -0.3 -0.6 -0.1 -0.2 -0.2 -0.8 -0.4 -0.7 -0.1 -0.2 -0.1 -0.3 -0.2 -0.6 -0.4 -0.0 -0.2 -0.3 0.0
Medication: Gliclazide 2.0 2.3 4.3 -1.6 -1.4 -1.4 -1.6 -1.5 -1.6 -1.3 -1.4 -1.2 -1.8 -1.8 -1.4 -0.9 -1.6 -1.4 -1.4 -1.8 -1.8 -1.7 0.9 -1.7 -1.1 -1.5 -1.3 -2.1 -1.6 -1.2 -1.5 -1.2 -1.4 -1.4 -1.4 -0.6 -1.9 -1.7 -0.8 -1.6 -1.8 -1.5 -1.5 -1.9 -1.8 -1.3 -1.8
Illnesses of father: None of the above (group 1) 6.8 8.4 12.5 3.2 3.3 3.2 3.0 2.6 3.1 3.5 3.3 3.1 2.6 2.2 3.1 2.9 2.3 2.9 2.9 2.7 3.1 3.0 -2.5 2.9 3.3 3.2 3.0 -0.2 3.1 3.4 3.3 3.2 3.3 2.2 3.2 1.4 2.3 1.9 2.5 3.3 2.7 2.4 3.3 3.0 2.9 3.3 3.1
Smoking status: Current 0.3 0.4 4.9 -0.5 -0.2 0.4 0.5 0.9 -0.6 -0.0 -0.3 -1.0 -0.7 -1.1 -0.7 0.8 0.2 0.1 -0.6 0.0 0.0 0.1 0.5 -0.2 -0.3 -0.5 -0.1 0.9 -0.5 0.1 -0.3 -0.8 -0.5 0.4 -0.2 2.2 0.6 1.2 -1.1 -0.3 0.5 0.7 0.1 -0.1 0.0 -0.3 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 1.9 0.2 -0.1 -0.1 -0.0 0.4 0.4 -0.4 -0.2 -0.4 0.8 0.8 -0.0 0.2 0.0 0.0 0.0 0.8 0.2 -0.1 0.2 -0.1 0.4 -0.2 -0.2 0.4 0.1 -0.6 0.4 -0.1 -0.1 0.4 -0.1 1.4 0.7 0.3 0.8 0.1 0.6 0.8 -0.0 -0.3 0.5 0.0 0.2
Whole body water mass 0.6 3.5 7.7 2.2 1.8 1.7 1.5 1.1 2.4 1.9 1.8 1.4 2.8 2.7 1.9 1.7 2.2 1.8 2.0 2.2 1.2 1.9 -2.3 2.2 2.0 1.7 1.9 0.6 2.2 1.1 1.9 2.0 1.9 1.8 1.9 1.1 1.7 0.6 1.9 1.9 2.5 1.5 1.7 1.5 2.1 1.9 1.6
Leg predicted mass (right) 0.6 3.1 6.6 2.0 1.7 1.7 1.7 1.4 1.9 1.9 1.7 1.0 2.3 2.1 1.9 1.4 2.0 1.9 1.8 2.1 1.1 1.9 -2.6 2.1 2.0 1.6 1.8 0.1 2.0 1.4 1.7 1.9 1.7 1.9 1.8 1.1 1.6 0.9 1.7 1.7 2.5 1.1 1.7 1.3 2.0 1.8 1.5
Arm fat mass (left) 0.5 1.9 4.0 1.5 1.4 1.2 1.4 1.3 1.5 1.4 1.4 1.0 1.3 1.4 1.8 2.0 1.7 1.6 0.8 1.5 1.0 1.5 -2.0 1.5 1.7 1.3 1.3 1.3 1.5 1.2 1.3 1.4 1.3 1.3 1.4 0.1 1.1 0.8 1.4 1.3 1.8 0.1 1.4 1.0 1.4 1.5 0.9
Number of self-reported non-cancer illnesses 3.2 5.5 12.1 -2.6 -2.1 -2.3 -2.3 -2.2 -2.7 -2.1 -1.9 -1.1 -3.5 -3.4 -2.0 -2.0 -2.3 -2.1 -2.8 -3.1 -1.9 -2.4 1.7 -2.4 -2.1 -1.9 -2.3 -0.9 -2.5 -1.4 -2.4 -2.0 -2.0 -2.5 -2.3 -2.2 -3.1 -2.1 -2.3 -2.3 -2.4 -3.1 -2.1 -2.2 -2.9 -2.0 -2.5
Average weekly champagne plus white wine intake 0.2 0.3 2.4 0.5 0.3 -0.0 0.1 -0.5 0.5 0.5 0.4 0.4 0.5 0.4 0.6 0.1 -0.8 0.5 0.6 0.0 -0.1 1.1 -1.5 -0.3 0.0 0.5 0.1 -0.1 0.4 0.3 0.0 0.8 0.5 -0.1 0.3 -1.5 -0.2 -0.6 0.1 0.3 0.1 -0.6 0.2 0.1 0.2 0.3 0.1
Miserableness 0.2 0.4 2.7 0.1 0.4 0.2 -0.4 -1.1 0.0 0.6 0.4 0.8 -0.8 -0.6 0.5 -1.1 -0.5 -0.2 0.1 -1.1 -0.2 -0.3 -1.0 -0.6 0.2 0.5 0.4 0.2 0.1 0.9 -0.3 0.8 0.4 -0.9 0.3 -0.5 -1.6 -1.4 1.1 0.0 -0.4 -0.5 -0.0 -0.3 -0.7 0.4 -0.3
Guilty feelings 1.1 1.6 4.7 -1.6 -1.1 -0.9 -0.8 -0.6 -1.8 -1.0 -1.3 -1.6 -1.8 -1.9 -1.4 -2.2 -1.1 -1.0 -1.6 -1.4 -1.5 -1.6 0.8 -1.7 -1.4 -1.4 -1.1 -0.3 -1.4 -0.9 -1.5 -1.6 -1.4 -0.7 -1.2 0.8 -1.1 -0.2 -1.4 -1.4 -0.3 -0.6 -1.1 -0.9 -1.4 -1.3 -1.0
Wears glasses or contact lenses 0.5 0.5 3.2 0.9 0.5 0.5 0.1 -0.4 1.5 0.5 0.6 0.9 1.4 1.8 0.5 0.9 -0.3 0.4 0.4 0.7 0.3 0.4 -0.7 0.2 0.2 0.5 0.5 0.7 0.8 -0.4 0.5 0.8 0.8 0.5 0.7 0.0 0.4 -0.6 1.0 0.7 0.8 0.7 0.3 1.1 0.7 0.4 0.7
Ever taken oral contraceptive pill 0.2 0.3 1.8 -0.4 -0.4 -0.3 -0.3 -0.5 -0.8 -0.1 -0.5 -0.6 -0.2 -0.3 -0.8 -0.5 -0.3 -0.2 -0.8 -0.3 -0.4 -0.2 0.3 -0.1 -1.1 -0.5 -0.4 -1.4 -0.5 -0.3 -0.7 -0.6 -0.5 -0.4 -0.4 -0.4 0.0 -0.2 -1.1 -0.4 -0.6 -0.5 -0.4 -0.2 -0.2 -0.7 -0.1
Hearing aid user 5.8 6.5 9.7 -2.8 -3.0 -3.0 -2.8 -2.3 -2.4 -2.5 -2.9 -2.7 -2.1 -2.1 -2.7 -2.2 -1.8 -2.9 -3.1 -2.4 -2.7 -2.8 2.8 -2.1 -2.6 -2.9 -2.7 -0.6 -2.9 -2.8 -2.6 -2.8 -2.9 -2.1 -3.0 -0.8 -2.0 -1.9 -2.3 -2.8 -1.9 -2.3 -2.9 -3.1 -2.6 -2.8 -2.7
Mother’s age at death 0.2 0.3 1.7 -0.3 -0.6 -0.5 -0.3 0.0 -0.6 -0.6 -0.5 -0.6 0.4 0.3 -0.7 -0.1 -0.4 -0.6 -0.3 0.3 -0.2 -0.6 1.3 -0.4 -0.5 -0.6 -0.7 -0.2 -0.5 -1.1 -0.1 -0.6 -0.5 0.2 -0.5 0.5 0.5 0.2 -0.4 -0.3 -0.1 0.4 -0.4 -0.5 0.1 -0.6 -0.2
Financial situation satisfaction 0.3 0.3 1.9 0.2 0.4 0.2 -0.3 -0.5 0.5 0.3 0.5 1.3 -0.3 -0.1 0.4 -0.8 -0.2 -0.2 0.3 -0.4 0.4 -0.1 -0.7 0.0 0.6 0.5 0.5 -1.4 0.3 0.5 0.4 0.6 0.6 -1.0 0.4 -1.3 -0.9 -1.0 0.3 0.3 0.0 -0.0 0.1 1.0 -0.3 0.5 0.2
Tinnitus: Yes, now most or all of the time 0.5 0.5 1.8 0.8 0.7 0.6 0.5 0.5 1.0 0.8 0.8 0.9 0.8 0.8 0.9 0.3 0.2 0.8 0.5 0.7 0.8 0.7 -0.6 0.7 0.8 0.8 0.5 -0.2 0.8 1.4 0.9 0.8 0.8 0.9 0.7 0.3 0.5 0.3 0.8 0.8 0.7 0.6 0.7 0.7 0.7 0.8 0.7
Commuting to job workplace: Public transport 2.1 2.5 7.4 -2.0 -1.8 -1.5 -0.8 0.0 -2.7 -1.8 -1.8 -2.4 -2.1 -2.5 -1.6 -1.5 -0.6 -1.3 -2.0 -1.2 -1.4 -1.2 1.7 -1.1 -1.3 -1.9 -1.8 -0.1 -1.8 -1.6 -1.6 -2.1 -2.1 -0.5 -1.9 -0.1 -0.5 0.7 -2.0 -1.8 -0.9 -1.4 -1.3 -1.4 -1.4 -1.6 -1.6
Eye problems/disorders: Glaucoma 0.3 0.3 3.5 0.3 -0.2 -0.2 0.0 -0.2 0.4 -0.4 -0.2 -0.6 1.4 1.3 -0.2 0.7 0.3 0.1 -0.2 0.7 -0.4 0.0 -0.1 0.4 -0.5 -0.3 0.1 1.9 0.1 -0.8 -0.2 0.0 -0.1 0.7 -0.1 1.0 0.9 -0.1 0.3 0.0 0.6 0.2 -0.2 -0.7 0.6 -0.4 -0.0
Medication: Blood pressure 0.6 1.2 5.2 1.1 1.1 1.0 0.9 0.6 1.0 0.6 1.2 1.6 0.5 0.3 1.3 0.8 1.9 1.1 0.4 0.6 1.0 0.9 -1.8 1.3 1.4 1.3 1.6 2.3 1.1 1.4 1.0 1.6 1.2 0.6 1.1 -0.2 0.1 0.1 1.5 1.1 0.8 -0.2 1.1 0.7 0.7 1.3 0.7
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.7 0.7 0.6 0.3 -0.1 -0.6 0.7 0.8 0.7 0.9 0.5 1.1 0.7 -0.1 -0.2 0.3 0.9 0.0 0.4 0.0 -1.3 -0.4 0.9 0.6 0.8 -0.9 0.8 0.3 0.5 1.1 0.7 -0.5 0.7 -0.4 -0.7 -1.1 0.9 0.5 0.5 0.3 0.3 0.4 0.1 0.7 0.2
Supplements: Fish oil (including cod liver oil) 0.0 0.1 0.5 0.1 0.0 0.2 0.0 0.1 -0.1 -0.1 0.1 0.4 0.2 0.2 0.1 0.6 0.0 0.2 -0.0 0.2 -0.3 0.1 0.3 -0.1 0.2 0.0 0.1 -0.2 0.1 0.3 0.2 -0.1 0.1 0.5 0.0 -0.7 0.1 0.1 0.2 0.1 -0.4 -0.1 0.1 0.5 0.1 0.1 0.2
High cholesterol (Self-reported) 0.4 0.7 2.0 -0.7 -0.7 -0.9 -1.0 -1.0 -0.5 -0.6 -0.6 -0.2 -0.8 -0.7 -0.5 -0.2 -0.1 -0.8 -1.3 -1.0 -1.1 -0.7 0.3 -0.7 -0.4 -0.6 -0.3 1.4 -0.8 -0.6 -0.7 -0.4 -0.6 -0.9 -0.8 -0.5 -1.2 -1.4 0.2 -0.7 -1.0 -1.2 -0.8 -1.3 -1.0 -0.6 -0.9
Medication: Bendroflumethiazide 0.7 1.1 3.2 1.3 1.1 0.8 0.9 0.5 1.1 0.6 1.1 1.2 1.4 1.0 1.1 0.9 1.5 1.1 1.0 1.0 0.7 0.9 -1.7 1.8 1.0 1.1 1.3 1.2 1.2 0.9 1.0 1.4 1.1 0.9 1.1 -0.1 0.8 0.1 1.3 1.1 0.8 0.3 1.0 0.4 1.0 1.0 0.8
Medication: Paracetamol 0.1 0.1 1.5 0.1 0.1 -0.0 -0.4 -0.7 0.4 0.1 0.1 0.5 0.2 0.4 -0.3 0.7 -0.1 -0.2 -0.1 -0.2 -0.3 0.2 -0.2 0.1 0.1 -0.1 0.0 0.3 0.1 -0.3 -0.0 0.4 0.2 -0.5 0.1 -0.3 -0.6 -1.2 0.2 0.0 -0.2 -0.3 -0.2 -0.1 -0.2 0.0 0.0
Medication: Lisinopril 0.8 1.1 2.7 -1.2 -1.3 -1.2 -0.8 -0.3 -1.0 -1.0 -1.3 -1.6 -0.6 -0.6 -1.1 0.0 -0.8 -0.8 -1.6 -0.5 -0.9 -1.1 1.3 -1.0 -1.1 -1.4 -1.6 1.0 -1.2 -1.3 -1.0 -1.5 -1.3 -0.4 -1.2 0.1 -0.1 0.2 -1.1 -1.2 -0.4 -0.9 -1.0 -0.9 -0.7 -1.2 -1.1
Medication: Atorvastatin 3.3 4.1 10.4 -2.5 -2.0 -2.0 -1.6 -1.1 -2.8 -1.9 -2.1 -2.1 -3.0 -3.2 -2.0 -1.1 -0.6 -1.7 -2.7 -2.3 -1.9 -2.4 1.5 -2.0 -1.9 -2.0 -1.5 0.8 -2.4 -1.4 -2.2 -2.3 -2.3 -1.6 -2.2 -0.9 -1.9 -0.7 -2.4 -2.3 -1.4 -2.3 -1.9 -1.9 -2.3 -2.0 -2.2
Illnesses of father: High blood pressure 0.2 0.3 2.1 -0.6 -0.2 -0.1 0.3 0.6 -0.6 -0.8 -0.4 -0.5 -0.9 -1.1 -0.3 -0.6 0.2 0.1 -0.7 -0.2 -0.2 0.1 0.7 -0.0 -0.5 -0.3 -0.2 1.5 -0.5 0.2 -0.4 -0.9 -0.5 -0.0 -0.3 -0.0 0.2 1.1 -1.0 -0.4 0.0 -0.4 -0.1 0.4 -0.2 -0.4 0.1
Alcohol drinker status: Never 0.2 0.2 0.9 -0.5 -0.3 -0.2 -0.2 -0.1 -0.7 -0.0 -0.3 -0.0 -0.9 -0.8 -0.5 -0.5 0.5 -0.4 0.0 -0.5 0.1 -0.6 0.6 0.1 -0.4 -0.2 -0.1 -1.0 -0.5 -0.5 -0.2 -0.5 -0.3 -0.5 -0.3 0.1 -0.4 0.2 -0.6 -0.3 -0.4 0.3 -0.2 0.0 -0.5 -0.3 -0.2
Ever smoked 0.7 1.2 3.2 1.2 1.3 1.2 1.1 0.8 1.2 1.2 1.3 1.3 0.8 0.7 1.3 0.4 -0.2 1.2 0.7 0.8 1.2 1.4 -0.7 0.8 0.8 1.3 1.1 1.1 1.1 1.8 1.0 1.1 1.3 1.1 1.2 0.8 0.8 0.7 1.1 1.3 0.8 0.9 1.3 1.0 1.1 1.1 1.3
Basal metabolic rate 0.7 3.6 7.0 2.2 1.9 1.7 1.6 1.2 2.3 2.0 1.8 1.5 2.6 2.5 2.0 2.0 2.2 1.9 1.9 2.2 1.3 2.0 -2.5 2.2 2.1 1.8 2.0 0.9 2.2 1.2 1.9 2.1 1.9 1.9 2.0 1.0 1.7 0.7 2.0 1.9 2.5 1.2 1.8 1.5 2.1 1.9 1.6
Leg fat percentage (left) 0.1 0.5 7.1 -0.0 -0.0 -0.2 -0.0 0.0 0.1 0.2 0.0 0.1 -0.3 -0.2 0.4 2.7 0.8 0.1 -0.8 -0.1 -0.4 0.2 -0.5 0.2 0.4 0.0 0.0 2.5 -0.0 -0.1 -0.1 0.1 -0.1 -0.1 -0.1 -1.3 -0.3 -0.2 0.6 -0.1 -0.1 -1.6 0.0 -0.4 -0.2 0.2 -0.6
Arm fat-free mass (left) 0.3 1.6 5.0 1.5 0.9 0.8 0.8 0.6 1.7 1.1 1.0 0.8 2.2 2.2 1.1 2.2 2.0 1.1 1.0 1.7 0.5 1.1 -1.5 1.6 1.3 0.9 1.1 1.6 1.4 0.2 1.2 1.2 1.1 1.3 1.1 0.8 1.2 0.2 1.5 1.2 1.8 0.7 0.9 0.7 1.4 1.1 0.9
Number of operations (self-reported) 0.5 0.8 2.5 -0.9 -0.7 -0.9 -0.8 -1.0 -0.9 -0.7 -0.6 -0.2 -1.5 -1.6 -0.4 -0.0 -1.2 -0.6 -1.1 -1.5 -0.4 -0.8 0.4 -0.9 -1.0 -0.5 -0.9 0.3 -1.0 0.0 -1.0 -0.6 -0.7 -0.7 -0.8 -1.2 -1.4 -0.8 -0.5 -0.8 -0.9 -1.5 -0.7 -0.7 -1.2 -0.7 -1.0
Average weekly beer plus cider intake 0.0 0.1 0.5 -0.1 -0.1 -0.1 -0.2 -0.1 -0.7 -0.0 -0.2 -0.0 -0.0 -0.0 -0.5 0.2 0.2 -0.0 -0.1 -0.0 -0.2 -0.4 -0.3 -0.4 0.1 -0.2 -0.2 0.7 0.0 -0.4 -0.0 -0.1 -0.2 -0.3 -0.0 -0.2 -0.1 -0.3 0.0 -0.2 0.1 -0.3 -0.2 0.1 -0.1 -0.1 0.2
Irritability 0.7 1.2 3.3 -1.1 -0.9 -0.8 -1.0 -1.0 -1.4 -1.1 -0.9 -1.3 -1.6 -1.5 -0.9 -1.0 -1.1 -0.7 -0.7 -1.5 -1.7 -1.2 -0.4 -1.8 -0.4 -1.0 -0.6 -0.8 -0.9 -0.5 -1.2 -0.7 -1.1 -0.8 -0.9 -0.4 -1.7 -1.2 -0.4 -1.2 -0.9 -1.3 -1.0 -1.5 -1.5 -0.6 -1.5
Risk taking 0.1 0.1 0.7 -0.0 -0.3 -0.2 -0.2 -0.4 -0.1 -0.0 -0.3 -0.2 0.3 0.4 -0.5 0.7 -0.1 0.1 0.3 -0.0 -0.4 0.1 0.0 -0.1 -0.6 -0.3 -0.3 0.7 -0.3 -0.8 -0.4 -0.2 -0.2 0.4 -0.2 -0.1 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.3 -0.4 0.0 -0.4 -0.2
Ever had prostate specific antigen (PSA) test 0.1 0.2 0.7 0.4 0.2 0.3 0.1 0.0 0.5 0.3 0.2 0.3 0.9 0.6 0.1 0.2 0.7 0.2 0.1 0.4 0.2 -0.1 -0.6 0.6 0.1 0.1 0.6 0.8 0.3 -0.1 0.4 0.5 0.3 0.6 0.3 0.5 0.5 -0.1 0.3 0.4 0.2 0.5 0.2 0.1 0.4 0.1 0.3
Fractured/broken bones in last 5 years 1.9 2.4 3.9 1.8 1.8 1.8 1.9 1.5 1.2 1.6 1.7 1.1 1.7 1.8 1.8 1.5 0.3 1.9 1.6 1.7 1.1 1.9 -1.6 1.1 1.3 1.7 1.6 0.6 1.7 2.0 1.5 1.6 1.6 1.3 1.8 0.3 1.7 1.4 0.7 1.7 1.7 0.6 1.8 1.6 1.9 1.6 1.9
Age started oral contraceptive pill 0.5 0.7 3.7 -0.7 -0.9 -0.8 -0.9 -1.0 -0.7 -0.7 -0.8 -0.5 -0.4 -0.0 -0.8 -1.9 -0.7 -0.7 -1.1 -0.7 -0.8 -1.4 0.7 -0.9 -0.8 -0.8 -0.8 0.7 -0.9 -0.9 -0.7 -0.6 -0.7 -0.2 -0.8 0.7 -0.7 -0.9 -0.1 -0.7 -0.5 -0.1 -0.9 -1.2 -0.7 -0.8 -0.9
Diastolic blood pressure, automated reading 0.1 0.3 2.1 -0.0 -0.3 -0.4 -0.2 -0.8 0.0 -0.3 -0.2 -0.3 0.3 0.6 -0.3 0.6 -0.6 -0.1 -0.8 -0.2 -0.8 -0.2 -0.0 -0.3 -0.8 -0.3 0.0 0.6 -0.5 -0.2 -0.7 -0.1 -0.2 0.4 -0.4 -0.2 -0.1 -0.8 0.2 -0.2 -0.8 -1.1 -0.4 -1.5 -0.1 -0.5 -0.6
Ever depressed for a whole week 0.2 0.3 1.0 -0.6 -0.6 -0.7 -0.6 -0.1 -0.6 -0.5 -0.6 -0.6 -0.4 -0.3 -0.5 -1.0 -0.5 -0.5 -0.7 -0.3 -0.5 -0.8 0.6 -0.9 -0.2 -0.6 -0.8 -0.3 -0.4 -0.7 -0.2 -0.6 -0.6 -0.3 -0.6 0.7 -0.3 0.1 -0.3 -0.6 0.6 0.2 -0.5 -0.2 -0.5 -0.4 -0.4
Unable to work because of sickness or disability 1.6 2.0 5.1 -1.5 -1.4 -1.5 -1.5 -1.2 -1.1 -1.6 -1.4 -1.1 -1.3 -1.4 -1.6 -1.7 -1.0 -1.9 -0.9 -1.2 -1.1 -1.6 1.9 -0.9 -1.6 -1.4 -1.9 -1.6 -1.5 -2.0 -1.2 -1.4 -1.3 -2.2 -1.4 -1.0 -1.0 -0.9 -2.0 -1.3 -1.2 -0.9 -1.4 -1.1 -1.3 -1.6 -1.0
Commuting to job workplace: Cycle 2.2 2.6 6.9 -1.9 -1.7 -1.1 -0.8 -0.3 -2.1 -1.6 -1.8 -2.6 -1.9 -2.1 -2.3 -0.6 -0.5 -1.3 -1.9 -1.2 -1.7 -1.3 1.6 -1.2 -2.1 -2.1 -1.5 -0.0 -2.1 -1.5 -1.9 -2.2 -2.1 -0.4 -1.7 1.5 -0.3 0.4 -2.3 -1.8 -1.4 -0.9 -1.4 -2.0 -1.3 -1.9 -1.5
Myopia 0.4 0.5 3.1 0.3 0.2 0.5 0.9 1.4 -0.3 0.3 0.1 -0.9 0.5 0.4 0.4 0.8 1.0 0.4 0.0 1.0 0.7 0.6 0.0 0.4 0.7 0.0 0.3 0.1 0.5 0.4 0.5 0.0 0.1 1.0 0.3 1.7 1.3 1.8 0.1 0.3 1.3 1.0 0.6 0.3 0.8 0.4 0.3
Vascular/heart problems diagnosed by doctor 0.1 0.3 1.7 0.3 0.3 0.5 0.5 0.9 0.3 0.8 0.2 -0.3 0.5 0.4 0.2 -0.1 0.8 0.4 1.0 0.8 0.6 0.2 0.5 0.5 0.3 0.1 0.4 -0.2 0.3 0.4 0.5 -0.2 0.2 0.7 0.3 1.1 1.0 1.0 -0.4 0.3 0.5 1.3 0.4 0.5 0.7 0.2 0.6
Cholesterol lowering medication 0.9 1.4 2.5 -1.2 -1.2 -1.4 -1.3 -1.4 -1.1 -1.5 -1.1 -1.1 -1.2 -1.4 -0.8 -0.7 -0.3 -1.2 -1.3 -1.4 -1.3 -1.1 0.4 -0.9 -1.2 -1.0 -1.0 0.9 -1.1 -1.3 -1.4 -0.8 -1.1 -1.4 -1.3 -1.0 -1.4 -1.1 -0.3 -1.3 -1.1 -1.6 -1.3 -1.6 -1.4 -1.1 -1.4
Medication: Omeprazole (e.g. Zanprol) 1.8 2.2 3.7 -1.6 -1.5 -1.6 -1.4 -1.5 -1.7 -1.6 -1.5 -1.4 -1.6 -1.7 -1.5 -1.2 -1.6 -1.3 -1.6 -1.7 -1.1 -1.5 1.3 -1.3 -1.9 -1.5 -1.7 -0.4 -1.7 -1.8 -1.7 -1.6 -1.5 -1.3 -1.5 -1.1 -1.4 -1.0 -1.9 -1.5 -1.3 -1.3 -1.5 -1.2 -1.6 -1.7 -1.5
Pain experienced in last month 0.5 0.8 2.0 1.0 0.9 0.7 0.7 0.7 1.1 0.9 0.9 0.8 1.1 1.0 1.1 0.1 0.4 0.8 0.6 0.9 0.7 0.8 -1.0 0.8 1.1 1.0 0.9 -0.2 1.0 1.4 1.0 1.0 1.0 1.0 0.8 0.5 0.6 0.3 1.4 0.9 0.6 0.9 0.8 0.5 0.9 0.9 0.8
Supplements: Calcium 2.3 2.5 5.1 1.6 1.8 1.8 1.8 1.8 1.2 1.7 1.7 1.4 1.2 1.2 1.7 0.5 1.1 1.5 2.1 1.5 1.8 1.6 -0.8 1.8 1.5 1.7 1.5 -0.1 1.7 1.5 1.7 1.3 1.6 1.2 1.7 0.9 1.6 1.8 1.0 1.7 1.8 2.0 1.8 2.2 1.6 1.7 2.0
Basal cell carcinoma (self-reported) 0.5 0.6 2.0 0.9 0.8 0.3 -0.1 -0.9 1.0 1.1 0.8 1.2 0.6 1.0 0.8 -0.6 -0.8 0.4 1.0 -0.2 0.3 0.7 -1.4 -0.1 0.5 0.9 0.4 -1.0 0.8 0.6 0.3 1.2 0.9 -0.3 0.8 -1.3 -0.7 -1.4 0.7 0.7 -0.0 -0.1 0.3 0.4 0.1 0.7 0.2
Heart attack/myocardial infarction (self-reported) 2.9 3.8 7.2 -1.9 -2.1 -2.1 -2.2 -2.3 -1.6 -2.0 -2.0 -1.4 -1.4 -1.4 -1.9 -2.2 -2.4 -2.3 -2.2 -1.8 -1.9 -2.1 2.0 -1.8 -2.3 -1.9 -2.2 -1.7 -2.1 -2.7 -2.0 -1.7 -1.9 -1.8 -2.1 -0.1 -1.7 -1.8 -1.3 -1.9 -1.3 -1.3 -2.2 -2.4 -1.9 -2.2 -1.8
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 2.5 -1.2 -1.0 -0.9 -0.6 -0.0 -1.2 -0.7 -1.0 -0.8 -1.3 -1.4 -0.7 -1.1 0.0 -0.8 -0.5 -0.8 -0.3 -0.8 1.6 -0.2 -0.7 -0.7 -1.4 0.2 -0.9 -0.8 -0.7 -1.3 -1.1 -0.6 -1.0 -0.6 -0.5 0.5 -1.4 -1.0 -0.5 -0.6 -0.7 -0.3 -0.9 -0.8 -1.0
Heart disease (siblings) 4.0 4.9 7.7 -2.3 -2.4 -2.5 -2.6 -2.6 -2.1 -2.0 -2.3 -1.8 -2.0 -1.7 -2.2 -1.9 -1.2 -2.4 -2.3 -2.5 -2.3 -2.5 1.4 -2.3 -2.1 -2.1 -2.0 -0.2 -2.3 -2.6 -2.4 -2.0 -2.2 -2.1 -2.4 -1.5 -2.5 -2.5 -1.4 -2.4 -2.2 -2.3 -2.5 -2.8 -2.5 -2.2 -2.7
Alcohol drinker status: Previous 0.3 0.3 3.6 0.0 -0.2 -0.0 0.1 0.5 -0.6 -0.1 -0.2 -0.8 0.6 0.4 -0.3 -0.0 1.0 0.4 -0.4 0.6 -0.1 0.1 -0.1 0.0 0.3 -0.3 -0.1 1.8 0.1 -0.7 0.1 -0.3 -0.3 1.0 -0.1 1.9 0.6 0.4 -0.1 -0.1 1.1 0.4 -0.0 -0.6 0.3 -0.0 -0.1
Pack years of smoking 0.2 0.3 1.9 -0.5 0.1 0.1 0.1 0.4 -0.7 0.1 -0.0 -0.2 -1.4 -1.4 -0.3 1.2 0.6 -0.1 -0.6 -0.8 -0.3 -0.0 -0.0 -0.3 0.2 -0.0 0.1 1.3 -0.3 0.2 -0.1 -0.4 -0.2 -0.9 0.0 0.2 -0.7 0.2 -1.1 -0.3 0.4 -0.2 0.1 0.2 -0.6 0.0 0.3
Impedance of whole body 0.1 0.7 3.1 -0.8 -0.4 -0.3 -0.2 -0.2 -1.3 -0.4 -0.3 -0.2 -1.6 -1.7 -0.6 -1.1 -1.8 -0.3 -0.5 -1.1 -0.1 -0.5 0.7 -0.9 -0.7 -0.3 -0.7 -0.9 -0.7 0.7 -0.7 -0.5 -0.5 -0.8 -0.5 -1.3 -0.9 0.0 -0.9 -0.6 -1.4 -0.8 -0.3 -0.0 -0.9 -0.4 -0.4
Leg fat mass (left) 0.2 0.7 6.6 0.6 0.5 0.3 0.6 0.6 0.8 0.7 0.5 0.4 0.6 0.6 0.9 2.6 1.3 0.7 -0.1 0.7 0.0 0.7 -1.2 0.7 1.0 0.5 0.5 2.0 0.6 0.3 0.5 0.6 0.5 0.7 0.5 -0.6 0.4 0.2 1.1 0.5 0.8 -0.9 0.6 0.2 0.6 0.7 0.0
Arm predicted mass (left) 0.4 1.9 5.6 1.6 1.1 0.9 0.8 0.6 2.0 1.2 1.1 1.0 2.4 2.3 1.2 2.0 1.9 1.1 1.1 1.7 0.6 1.2 -1.6 1.7 1.4 1.1 1.2 1.5 1.5 0.3 1.3 1.4 1.2 1.4 1.2 0.8 1.2 0.1 1.6 1.3 2.0 0.8 1.0 0.8 1.5 1.2 0.9