TWAS hub - AKAP11

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1650	0.0340	3.8e-14	0.205	0.124	0.185	0.189	0.195	1.8e-24	8.1e-15	5.6e-22	1.5e-22	3.6e-23
2	GTEx	Artery Aorta	0.2560	0.0810	1.9e-04	0.089	NA	0.069	NA	0.114	1.3e-05	NA	1.2e-04	NA	7.7e-07
3	GTEx	Artery Tibial	0.1729	0.0435	7.4e-08	0.113	NA	0.137	NA	0.140	3.6e-09	NA	7.2e-11	NA	4.3e-11
4	GTEx	Brain Cerebellar Hemisphere	0.2070	0.0830	3.5e-03	0.202	NA	0.111	NA	0.186	6.6e-06	NA	8.8e-04	NA	1.6e-05
5	GTEx	Brain Cerebellum	0.3030	0.0850	2.1e-05	0.293	NA	0.296	NA	0.244	2.5e-09	NA	2.1e-09	NA	8.0e-08
6	GTEx	Brain Hypothalamus	0.3590	0.1150	3.6e-03	-0.002	NA	-0.008	NA	-0.004	3.5e-01	NA	5.5e-01	NA	4.1e-01
7	GTEx	Colon Sigmoid	0.2100	0.0770	2.2e-03	0.060	NA	0.066	NA	0.091	3.7e-03	NA	2.3e-03	NA	4.0e-04
8	GTEx	Esophagus Gastroesophageal Junction	0.1690	0.0710	8.8e-03	-0.008	NA	-0.007	NA	-0.008	8.4e-01	NA	7.0e-01	NA	8.0e-01
9	GTEx	Esophagus Mucosa	0.2460	0.0590	7.6e-09	0.178	NA	0.150	NA	0.170	5.3e-12	NA	3.2e-10	NA	1.6e-11
10	GTEx	Esophagus Muscularis	0.2270	0.0590	2.7e-07	0.192	NA	0.177	NA	0.185	8.5e-12	NA	6.0e-11	NA	2.1e-11
11	GTEx	Lung	0.0813	0.0388	1.0e-02	-0.002	NA	-0.003	NA	0.017	5.5e-01	NA	6.6e-01	NA	1.8e-02
12	GTEx	Muscle Skeletal	0.1451	0.0388	2.4e-07	0.103	NA	0.086	NA	0.104	3.0e-10	NA	7.8e-09	NA	2.4e-10
13	GTEx	Nerve Tibial	0.1235	0.0424	4.4e-04	-0.004	NA	0.011	NA	0.009	9.3e-01	NA	5.1e-02	NA	7.0e-02
14	GTEx	Skin Not Sun Exposed Suprapubic	0.1390	0.0520	1.1e-03	-0.004	NA	-0.002	NA	-0.003	6.9e-01	NA	4.1e-01	NA	4.8e-01
15	GTEx	Skin Sun Exposed Lower leg	0.0570	0.0250	5.4e-03	0.051	NA	0.036	NA	0.037	4.7e-05	NA	5.6e-04	NA	4.6e-04
16	GTEx	Testis	0.1500	0.0540	1.2e-03	0.034	NA	0.093	NA	-0.004	1.2e-02	NA	6.4e-05	NA	5.6e-01
17	METSIM	Adipose	0.0346	0.0161	5.3e-03	0.011	0.005	0.004	0.005	0.006	8.2e-03	5.9e-02	8.3e-02	4.7e-02	3.7e-02
18	TCGA	Breast Invasive Carcinoma	0.0540	0.0320	3.7e-04	0.007	0.023	0.026	NA	0.009	9.8e-03	1.2e-05	3.8e-06	NA	4.1e-03
19	TCGA	Brain Lower Grade Glioma	0.0336	0.0192	6.9e-03	-0.002	0.016	0.000	NA	0.000	5.7e-01	5.0e-03	3.2e-01	NA	3.2e-01
20	TCGA	Lung Squamous Cell Carcinoma	0.0410	0.0187	5.2e-05	0.052	0.044	0.039	NA	0.045	1.5e-06	8.6e-06	3.0e-05	NA	7.1e-06
21	TCGA	Ovarian Serous Cystadenocarcinoma	0.0410	0.0240	7.4e-03	0.003	0.018	0.005	NA	0.005	1.9e-01	2.1e-02	1.3e-01	NA	1.4e-01
22	TCGA	Thyroid Carcinoma	0.0710	0.0270	1.9e-06	0.087	0.052	0.057	NA	0.079	7.4e-09	8.7e-06	3.0e-06	NA	3.7e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Heel T-Score	8.4	66.6	139.2	7.7	6.5	8.5	8.5	8.9	-0.1	5.8	5.6	9.5	7.9	9.0	-7.6	9.3	7.2	7.8	11.6	7.2	5.2	8.5	10.1	11.8	7.6
Alcohol usually taken with meals	7.4	12.0	21.3	-3.7	-2.8	-3.3	-3.9	-3.9	-1.4	-3.8	-4.3	-4.6	-3.8	-0.3	3.7	-4.0	-4.5	-3.8	-1.9	-3.9	-2.7	-2.8	-2.6	-3.3	-3.7
Ever had prostate specific antigen (PSA) test	6.2	7.1	13.5	-3.0	-1.5	-3.6	-2.7	-3.4	0.4	-2.8	-1.6	-3.3	-2.8	1.9	2.9	-2.1	-2.2	-2.9	-1.9	-2.3	-2.3	-2.2	-3.7	-3.6	-2.9
Mouth/teeth dental problems: Dentures	5.1	8.6	15.1	3.4	2.7	2.7	3.5	3.4	-0.9	3.8	2.4	3.9	3.5	-0.2	-3.4	2.6	2.8	3.6	0.1	3.8	1.7	2.4	3.2	2.6	3.3
HDL Cholesterol	4.9	8.2	13.8	-3.6	-3.1	-3.6	-3.4	-3.5	-1.2	-1.5	-2.4	-3.4	-3.4	-0.2	3.7	-2.7	-0.9	-3.5	-0.7	-3.2	-1.5	-2.2	-3.4	-3.2	-3.7
Osteoporosis (self-reported)	4.5	5.6	15.1	-2.0	-1.7	-2.4	-2.1	-2.4	-1.6	-2.6	-1.7	-2.7	-2.0	-1.9	1.9	-3.1	-1.9	-2.1	-3.9	-2.6	-2.5	-1.8	-2.9	-3.2	-2.0
Mouth/teeth dental problems	4.4	6.7	12.2	-2.6	-2.2	-2.7	-2.7	-2.8	0.9	-3.5	-2.3	-3.5	-2.7	-1.3	2.6	-3.1	-2.8	-2.5	-2.0	-2.5	-1.4	-2.8	-2.9	-2.9	-2.5
Heel bone mineral density (BMD) T-score, automated (right)	4.2	9.5	21.7	2.8	2.1	3.0	3.3	3.1	1.8	2.6	3.1	3.5	3.0	3.5	-2.8	3.4	2.7	2.5	4.7	2.4	0.1	3.5	3.9	4.5	2.7
Qualifications: O levels/GCSEs or equivalent	4.1	6.6	16.5	-2.3	-2.3	-2.3	-2.4	-2.9	0.9	-3.4	-2.3	-3.1	-2.3	0.2	2.8	-4.1	-2.6	-2.4	-3.0	-2.5	-1.5	-2.2	-2.5	-3.2	-2.3
Had menopause	4.0	5.0	8.6	2.7	2.4	2.3	2.9	2.9	-0.5	1.3	0.7	2.5	2.9	0.3	-2.9	1.6	0.4	2.8	-0.2	2.9	1.9	1.7	2.7	2.5	2.8
Supplements: Calcium	4.0	4.4	9.7	-1.9	-0.8	-2.5	-2.3	-2.3	0.3	-2.8	-0.5	-2.5	-2.0	-0.2	2.0	-2.5	-3.1	-2.1	-2.2	-1.4	-0.9	-2.1	-3.1	-2.9	-1.8
Crohns Disease (2012)	3.9	6.2	15.4	2.2	1.8	2.8	2.1	2.0	1.3	3.7	3.9	2.9	2.2	-0.1	-1.4	1.9	3.7	1.7	3.5	1.5	1.9	2.9	2.8	2.9	1.9
Qualifications: A levels/AS levels or equivalent	3.8	8.4	15.1	-2.9	-2.4	-2.9	-2.7	-3.4	0.5	-3.7	-3.2	-3.9	-3.0	0.7	3.2	-3.6	-2.7	-3.1	-2.4	-2.8	-1.7	-3.1	-2.7	-3.3	-2.9
Leg fat percentage (left)	3.7	13.3	22.6	4.5	3.8	3.6	4.6	4.6	0.4	3.1	3.2	4.8	4.6	-0.3	-4.4	3.8	2.2	4.4	-0.2	4.6	2.9	3.0	3.1	3.4	4.5
Age at First Birth	3.5	5.1	16.0	-2.3	-2.5	-1.3	-2.3	-2.1	0.7	-2.3	-3.0	-2.8	-2.4	-1.1	1.7	-1.6	-4.0	-2.0	-0.7	-2.9	-2.6	-3.3	-0.8	-1.3	-2.1
Alcohol intake frequency.	3.5	8.2	15.6	3.7	2.0	3.3	4.0	3.7	0.7	1.5	1.8	3.1	3.8	-2.3	-3.1	2.6	1.2	3.8	-0.7	3.7	2.8	1.8	3.3	2.6	3.7
Pulse wave Arterial Stiffness index	3.4	4.0	7.5	2.4	1.4	2.1	2.3	2.1	-0.7	0.5	1.5	2.0	2.3	1.9	-1.9	2.1	2.4	2.0	-0.7	2.4	2.7	2.2	2.0	1.9	2.4
Crohns Disease (2017)	3.3	7.3	24.6	2.2	1.2	2.4	1.9	1.8	1.8	4.3	5.0	3.2	2.2	1.1	-1.5	1.8	4.8	1.3	3.8	1.7	1.3	3.8	2.0	2.3	1.9
Leg fat mass (left)	3.3	13.0	21.7	4.6	3.4	3.9	4.5	4.6	0.2	3.0	2.7	4.7	4.7	0.2	-4.3	3.9	1.4	4.5	0.1	4.5	2.9	2.0	3.7	3.8	4.6
Leg fat percentage (right)	3.2	11.6	19.9	4.3	3.6	3.2	4.3	4.3	0.4	2.7	3.0	4.5	4.4	-0.3	-4.2	3.5	1.8	4.1	-0.7	4.4	2.4	3.0	2.6	3.0	4.3
Pulse wave peak to peak time	3.1	3.6	7.0	-2.3	-1.4	-2.0	-2.2	-2.0	0.4	-0.4	-1.5	-1.8	-2.1	-1.7	1.8	-2.2	-2.3	-1.9	0.7	-2.3	-2.6	-2.3	-2.0	-1.8	-2.2
Leg fat mass (right)	3.0	11.7	20.2	4.4	3.2	3.6	4.3	4.4	0.1	2.8	2.6	4.5	4.5	0.2	-4.2	3.6	1.3	4.3	-0.2	4.4	2.6	2.0	3.3	3.4	4.4
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.6	26.5	1.8	1.3	2.4	2.5	2.3	1.0	2.3	2.3	2.7	2.1	2.8	-2.0	2.8	2.7	1.8	5.1	1.3	-0.4	2.4	4.0	4.1	1.8
Body fat percentage	2.9	11.3	19.2	4.1	3.3	3.5	4.1	4.2	-0.2	3.0	2.9	4.4	4.2	-0.5	-4.1	3.6	1.8	4.0	0.2	4.1	2.6	2.7	3.2	3.4	4.1
Whole body fat mass	2.9	12.0	19.8	4.3	3.2	3.9	4.2	4.4	0.0	3.0	2.7	4.4	4.4	0.2	-4.2	3.8	1.1	4.3	0.4	4.2	2.6	1.9	3.7	3.7	4.3
Alzheimer’s Disease (in father)	2.8	3.1	5.9	2.2	2.1	1.6	2.0	1.9	2.4	0.3	1.7	1.7	2.2	1.2	-2.0	1.4	0.6	2.1	-1.1	2.2	0.6	1.8	1.9	1.0	2.1
Allergy or Eczema	2.8	7.4	19.8	2.6	1.9	3.1	2.4	2.2	0.3	4.5	4.1	3.3	2.6	0.8	-1.8	2.3	3.1	1.8	2.7	2.5	1.4	2.8	3.9	3.3	2.4
Trunk fat percentage	2.8	11.1	19.1	3.9	3.2	3.5	3.9	4.2	-0.6	3.3	2.8	4.4	4.1	-0.5	-4.0	3.6	1.8	4.0	0.6	4.0	2.7	2.5	3.3	3.5	4.0
Trunk fat mass	2.7	11.7	20.0	4.2	3.1	3.8	4.1	4.3	-0.2	3.2	2.6	4.5	4.3	0.0	-4.1	3.6	1.3	4.2	0.6	4.2	2.8	1.9	3.6	3.7	4.2
Schizophrenia vs Biploar Disorder	2.6	3.5	6.8	2.5	1.3	2.6	2.3	2.4	-0.2	1.3	0.4	2.2	2.3	-1.2	-2.1	0.8	-0.0	2.4	0.2	2.0	1.7	1.1	2.6	2.2	2.5
Wheeze or whistling in the chest in last year	2.6	4.7	8.1	2.4	2.2	2.7	2.0	2.4	-0.0	2.4	2.0	2.6	2.3	0.5	-2.5	1.7	1.6	2.3	0.8	2.8	2.4	2.1	2.7	2.5	2.4
Allergy	2.5	5.8	14.0	-2.5	-1.1	-2.8	-2.3	-2.1	-0.2	-3.4	-3.2	-3.0	-2.5	-1.6	1.9	-2.2	-2.6	-2.0	-1.7	-2.7	-0.9	-2.2	-3.7	-2.9	-2.4
Hayfever/allergic rhinitis (self-reported)	2.5	3.4	10.5	1.9	2.4	1.5	1.8	1.5	1.0	1.5	3.2	2.1	1.9	-0.9	-1.1	2.0	2.6	1.5	1.6	2.4	2.0	1.2	1.2	1.1	1.8
Medication: Lansoprazole	2.5	2.8	5.2	-1.9	-1.5	-2.1	-1.7	-1.9	1.6	-1.6	-0.6	-2.0	-1.8	1.1	1.5	-1.3	-2.1	-1.2	-2.3	-1.9	-1.1	-1.3	-1.3	-2.2	-1.8
Lung cancer (father)	2.4	2.8	10.2	1.4	0.6	1.3	1.3	1.4	-1.6	3.2	2.3	2.1	1.5	0.4	-1.0	1.1	1.7	0.8	2.7	1.6	1.2	2.0	1.5	2.1	1.3
Qualifications: College or University degree	2.4	7.5	16.7	-2.7	-2.5	-2.3	-2.8	-3.1	-1.4	-4.1	-3.4	-3.7	-2.8	0.5	2.7	-3.8	-2.2	-2.4	-1.8	-3.0	-1.3	-3.1	-2.3	-3.0	-2.6
Mouth/teeth dental problems: Loose teeth	2.4	2.9	11.3	1.3	1.6	1.2	1.1	1.4	-0.8	2.3	3.1	1.9	1.2	0.8	-1.2	1.7	3.4	1.1	1.8	1.4	1.6	1.9	0.9	1.3	1.2
Average weekly red wine intake	2.4	3.6	7.8	-2.0	-1.3	-2.2	-1.9	-2.1	0.5	-1.4	-1.9	-2.3	-2.0	0.6	1.7	-1.4	-2.8	-1.9	-1.6	-1.7	-2.1	-2.3	-2.1	-2.3	-1.8
Wears glasses or contact lenses	2.4	2.8	7.5	2.0	2.7	1.8	2.0	1.7	0.9	0.6	1.7	1.8	2.0	0.1	-2.0	0.8	1.1	1.7	-0.3	2.0	1.1	2.5	1.6	1.3	1.9
Qualifications: CSEs or equivalent	2.2	2.9	12.1	1.4	0.2	1.6	1.2	1.6	0.5	1.4	1.7	1.8	1.5	-1.0	-0.8	1.9	2.5	0.8	3.5	1.5	1.5	2.5	1.6	2.3	1.3
Age at last live birth	2.2	3.2	6.3	-2.3	-1.5	-1.7	-2.5	-2.2	0.5	-1.2	-1.0	-2.4	-2.2	-0.6	2.0	-1.4	-2.0	-2.1	0.9	-2.2	-2.2	-1.8	-0.9	-1.3	-2.3
Qualifications: nursing, teaching	2.2	3.4	8.0	-1.3	-0.9	-1.8	-1.5	-1.8	1.2	-2.4	-1.8	-2.3	-1.5	-0.7	2.0	-1.9	-2.8	-1.6	-2.4	-0.9	0.0	-2.2	-2.8	-2.6	-1.3
Unable to work because of sickness or disability	2.2	2.8	7.7	1.5	1.2	1.3	1.6	2.0	-0.9	0.7	2.1	1.8	1.7	0.0	-2.1	2.0	2.8	2.2	0.9	2.0	1.2	2.2	1.2	1.6	1.5
Bipolar Disorder (2011)	2.1	2.0	4.6	-1.6	-0.3	-1.7	-1.3	-1.9	0.7	-1.4	-1.1	-1.6	-1.5	0.7	1.4	-1.3	-1.0	-1.7	-0.9	-1.3	-1.9	-1.3	-1.7	-2.2	-1.5
Hypothyroidism (self reported)	2.1	4.8	25.7	1.0	1.3	0.0	1.2	0.7	1.3	-5.0	-3.6	-1.2	0.9	-0.3	-0.9	-0.5	-4.8	1.2	-5.1	0.5	-1.0	-2.1	0.1	-0.9	1.3
Alcohol intake versus 10 years previously	2.1	3.2	6.7	2.3	1.6	1.8	2.5	2.0	-1.4	1.5	0.9	1.9	2.3	-1.6	-2.2	1.5	1.8	2.6	-1.1	2.0	1.1	0.2	1.6	0.7	2.3
Arm fat-free mass (right)	2.1	10.6	18.2	4.2	2.3	3.9	4.0	4.0	0.6	2.5	1.8	4.1	4.3	1.7	-3.8	3.5	0.1	4.2	1.0	3.8	2.3	0.6	3.9	3.9	4.3
Arm predicted mass (right)	2.1	10.5	18.1	4.2	2.4	3.8	4.0	4.0	1.0	2.6	1.7	4.1	4.2	1.8	-3.8	3.4	-0.2	4.2	0.9	3.8	2.3	0.4	3.9	3.9	4.3
Eye problems/disorders: Cataract	2.1	2.4	4.9	1.8	1.9	1.8	2.1	1.8	1.2	0.2	0.5	1.6	1.8	-0.1	-2.1	2.2	1.1	2.0	-1.1	1.2	0.2	0.9	1.9	1.4	1.9
Relative age voice broke	2.0	3.0	8.9	-2.3	-2.4	-1.8	-2.5	-1.9	-1.1	-0.5	-0.4	-1.4	-2.1	-0.3	2.1	0.6	1.2	-2.1	3.0	-2.1	-0.7	-0.1	-1.6	-0.7	-2.4
Hayfever, allergic rhinitis or eczema	2.0	4.4	13.1	2.1	1.1	2.7	2.0	1.8	0.1	3.0	2.7	2.6	2.2	0.9	-1.6	2.0	2.1	1.7	1.7	1.7	0.7	1.8	3.6	2.9	1.9
Blood Eosinophil Count	1.9	14.3	30.7	5.0	4.6	4.0	5.0	4.5	1.9	-4.2	-1.9	2.0	4.7	-0.1	-4.8	2.3	-1.9	4.8	-5.5	4.7	3.1	-0.1	2.7	1.8	5.3
Relative age of first facial hair	1.9	3.8	7.4	-2.6	-1.9	-2.7	-2.6	-2.4	-0.3	-0.7	-1.0	-1.9	-2.4	-0.4	2.4	-0.7	0.1	-2.6	1.9	-2.4	-1.9	-0.2	-2.6	-1.8	-2.7
Number of incorrect matches in round	1.9	3.1	6.6	-1.9	-0.9	-2.3	-2.0	-1.9	-1.2	-0.1	-1.1	-1.7	-2.0	-0.8	1.9	-2.5	-1.3	-1.9	-1.3	-1.8	-1.8	-1.2	-2.2	-2.6	-2.0
Weight	1.9	9.5	16.2	4.0	2.6	3.5	3.8	3.9	0.4	2.3	1.8	3.9	4.0	1.2	-3.7	3.4	0.5	4.0	0.3	3.8	2.7	0.6	3.3	3.4	4.0
Handedness (chirality/laterality): Left-handed	1.9	2.3	4.8	1.9	1.0	2.1	2.2	1.7	1.5	0.9	0.9	1.4	1.9	0.9	-1.2	1.1	1.1	1.5	1.3	1.8	1.7	0.9	1.9	1.8	1.8
Osteoarthritis (self-reported)	1.9	2.4	8.9	0.8	1.3	1.5	0.8	1.0	1.5	1.9	2.2	1.7	0.9	0.6	-1.1	2.0	2.3	0.5	3.0	0.8	1.4	2.0	1.2	2.1	0.8
Arm fat mass (left)	1.9	7.9	13.1	3.5	2.5	3.1	3.4	3.6	-0.0	2.2	2.1	3.6	3.6	0.3	-3.4	3.6	0.9	3.5	0.8	3.3	2.0	1.4	3.0	3.3	3.5
Financial situation satisfaction	1.9	2.4	4.9	-1.9	-2.2	-1.5	-2.0	-1.7	0.5	-1.2	-1.7	-1.8	-1.9	1.0	1.7	-0.2	-0.9	-2.0	2.0	-1.6	0.7	-1.1	-1.4	-0.6	-1.9
Arm predicted mass (left)	1.9	9.6	17.4	4.1	2.5	3.6	3.9	3.8	0.8	2.4	1.7	3.8	4.1	1.5	-3.8	3.1	-0.2	4.1	0.3	3.7	2.5	0.2	3.5	3.5	4.2
Chronic bronchitis/emphysema (father)	1.8	2.1	4.2	2.0	0.7	1.7	2.0	1.8	0.6	1.4	0.3	1.8	2.0	-0.3	-1.5	0.6	-0.7	1.8	-0.3	1.9	1.5	0.9	1.5	1.4	2.0
Depression (Nagel 2018)	1.7	2.6	5.6	2.3	1.0	1.8	2.2	2.1	-0.7	-0.5	0.1	1.8	2.4	0.2	-1.8	1.5	-0.5	2.3	0.4	1.8	1.9	1.0	1.3	1.7	2.3
Pulse rate	1.7	2.9	6.7	-2.2	-2.6	-1.4	-2.0	-2.1	-2.1	-0.8	-1.6	-1.9	-2.1	0.2	1.7	-0.9	-0.7	-2.3	1.8	-2.3	-1.0	-1.6	-0.7	-0.3	-2.1
Arm fat mass (right)	1.7	7.0	11.7	3.3	2.3	2.9	3.3	3.4	-0.1	1.9	1.9	3.4	3.4	0.2	-3.2	3.4	0.8	3.3	0.5	3.2	2.1	1.2	2.9	3.0	3.3
Hypothyroidism/myxoedema (self-reported)	1.7	3.4	17.8	1.1	1.1	0.2	1.2	0.8	1.3	-3.9	-2.9	-0.7	1.0	-0.3	-1.0	-0.5	-4.1	1.2	-4.2	0.7	-0.9	-1.3	0.3	-0.7	1.3
Illnesses of siblings: Diabetes	1.7	2.1	6.7	1.7	1.7	1.3	1.6	1.6	-2.6	-0.5	0.6	1.3	1.8	0.2	-1.8	0.3	0.3	1.8	-0.7	1.9	1.3	1.6	1.9	1.0	1.6
Arm fat-free mass (left)	1.7	8.8	15.8	3.9	2.3	3.4	3.7	3.7	0.7	2.2	1.6	3.7	3.9	1.6	-3.5	3.0	-0.2	3.9	0.4	3.6	2.5	0.0	3.4	3.4	4.0
Irritability	1.7	2.8	6.0	2.2	1.4	1.8	2.3	2.1	-0.2	-0.7	-0.1	1.5	2.3	-0.8	-2.4	2.3	-0.6	2.4	-1.3	2.0	0.2	0.4	1.9	1.2	2.3
Medication: Atenolol	1.6	2.0	4.7	1.2	0.5	1.5	1.3	1.6	0.2	1.5	0.9	1.6	1.2	-0.7	-1.6	0.8	2.2	1.5	1.8	1.2	2.0	1.6	1.4	1.6	1.3
Body mass index (BMI)	1.6	6.6	13.4	3.2	2.1	2.6	3.1	3.3	0.4	1.7	1.8	3.3	3.3	1.0	-3.1	3.7	0.8	3.2	0.6	3.1	1.7	1.3	2.6	3.0	3.2
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	3.6	-1.4	-1.9	-1.7	-1.5	-1.6	0.0	-1.5	-1.0	-1.6	-1.3	-0.2	1.5	-1.5	-1.7	-1.6	-0.1	-1.8	-1.6	-1.0	-1.8	-1.3	-1.5
Number of full brothers	1.6	2.0	6.1	1.6	1.5	1.6	1.3	1.5	0.2	1.2	1.4	1.6	1.5	0.1	-1.0	1.5	0.7	1.3	0.2	1.8	2.5	1.8	1.5	1.5	1.5
Arm fat percentage (left)	1.6	6.3	10.8	2.9	2.4	2.7	3.0	3.2	-0.4	2.1	2.2	3.3	3.1	-0.5	-2.9	3.2	1.5	2.9	0.8	2.9	1.6	2.1	2.6	2.7	2.9
Risk taking	1.6	2.3	5.1	-1.8	-2.0	-1.5	-1.9	-1.9	-0.6	0.1	-1.0	-1.7	-1.7	0.3	2.3	-1.5	-0.8	-2.2	2.2	-1.8	-0.7	-1.4	-0.9	-0.5	-1.9
Rheumatoid Arthritis	1.5	2.0	10.0	1.0	0.3	1.4	0.8	1.2	0.2	3.2	2.2	2.2	1.1	-0.6	-1.1	0.9	1.8	1.0	1.4	0.7	1.5	1.7	1.1	1.3	0.9
Sensitivity / hurt feelings	1.5	2.6	9.2	-1.6	-3.0	-1.2	-1.5	-1.7	-1.2	-1.6	-1.5	-1.8	-1.4	-1.0	1.5	-0.8	-2.0	-1.4	-0.9	-2.0	-1.7	-2.2	-0.3	-1.2	-1.6
Pain all over the body in last month	1.5	1.6	3.3	1.4	0.1	1.5	1.0	1.4	-1.4	1.4	0.6	1.6	1.2	0.9	-1.4	1.3	1.4	1.2	1.1	0.8	0.8	1.8	1.4	1.6	1.3
Medication: Omeprazole	1.5	1.8	4.9	1.3	1.0	0.9	1.5	1.4	0.4	0.8	1.4	1.6	1.4	0.9	-1.6	1.4	1.9	1.3	-1.6	1.6	0.6	2.2	0.9	0.7	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	7.2	1.1	1.9	1.1	1.1	1.5	0.7	0.5	1.2	1.4	1.1	1.7	-1.0	1.2	0.9	0.8	2.7	0.9	0.6	1.8	1.1	2.2	1.1
Blood White Count	1.4	10.6	21.6	-4.4	-4.5	-3.4	-4.4	-3.8	-0.2	-0.6	-2.3	-3.4	-4.4	-0.1	4.2	-1.8	0.0	-4.6	3.5	-4.6	-2.4	-1.2	-2.3	-1.7	-4.6
Ever had hysterectomy (womb removed)	1.4	1.5	3.3	1.7	0.6	1.4	1.8	1.7	0.3	-0.3	0.2	1.1	1.7	-0.3	-1.5	1.2	-1.0	1.7	-1.0	1.2	1.7	0.2	0.8	1.0	1.8
Medication: Levothyroxine sodium	1.4	2.3	18.8	0.4	0.7	-0.4	0.5	0.1	0.4	-3.5	-2.1	-1.0	0.4	0.1	-0.5	-0.9	-2.8	0.4	-4.3	0.1	-1.4	-0.2	-0.3	-1.5	0.5
Had other major operations	1.4	1.7	6.4	0.8	1.7	1.1	0.9	0.8	0.0	2.5	1.9	1.4	0.8	0.8	-1.0	1.5	1.5	0.7	1.3	1.3	1.4	1.6	1.5	1.2	0.8
Age at first live birth	1.4	2.5	4.7	-1.8	-1.0	-1.5	-2.2	-2.0	1.4	-0.9	-0.5	-2.1	-1.9	0.2	1.8	-1.9	-0.9	-1.9	-0.2	-1.9	-2.0	-1.2	-1.3	-1.8	-1.8
Primary Biliary Cirrhosis	1.3	1.8	11.4	-0.4	-0.4	-0.9	-0.5	-0.8	-1.2	-3.2	-1.4	-1.5	-0.4	0.5	0.9	-0.6	-1.5	-0.5	-3.4	0.2	-0.1	-0.5	-1.5	-1.9	-0.4
BMI	1.3	7.5	14.5	3.6	2.0	2.6	3.7	3.4	0.4	1.9	1.6	3.5	3.8	1.1	-3.3	3.5	0.2	3.5	-0.6	3.8	1.5	0.9	2.8	2.5	3.7
Ever used hormone-replacement therapy (HRT)	1.3	1.7	3.3	1.7	0.7	1.5	1.8	1.3	0.7	-0.9	0.5	0.9	1.7	-0.6	-1.7	1.2	-0.7	1.1	-1.4	1.6	1.1	1.8	1.1	1.1	1.7
Maternal smoking around birth	1.3	1.8	5.0	1.7	0.6	0.9	1.5	1.7	-0.4	1.3	0.4	1.9	1.6	0.6	-1.8	0.7	2.0	2.1	0.3	2.2	0.9	0.7	0.7	0.8	1.8
Waist circumference	1.3	4.9	8.9	2.6	1.7	2.4	2.5	2.6	0.7	2.4	1.9	2.9	2.6	0.9	-2.6	3.0	1.4	2.4	1.1	2.2	1.5	1.3	2.3	2.7	2.6
Arm fat percentage (right)	1.3	5.0	8.8	2.6	2.2	2.3	2.6	2.8	-0.2	1.7	2.0	2.9	2.7	-0.6	-2.6	3.0	1.2	2.6	0.4	2.6	1.8	1.7	2.2	2.4	2.6
Medication: Amlodipine	1.3	1.8	4.2	1.7	0.8	1.5	1.5	1.9	-0.7	1.5	0.6	1.7	1.6	-0.8	-2.0	1.2	0.9	1.5	0.6	1.4	0.7	1.5	1.3	1.3	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	4.2	-1.3	-2.0	-1.3	-1.3	-1.5	-0.6	-1.4	-1.0	-1.6	-1.2	-1.0	1.2	-1.2	-0.8	-1.2	-0.7	-1.2	-0.7	-1.9	-1.6	-1.7	-1.3
Heart attack/myocardial infarction (self-reported)	1.3	1.7	6.6	1.5	0.6	0.9	1.6	1.5	-0.6	1.0	1.1	1.6	1.4	0.0	-1.2	1.2	1.6	1.4	0.5	1.6	2.6	1.1	0.7	0.8	1.5
LDL Cholesterol	1.2	1.9	5.3	-1.7	-2.3	-1.6	-1.6	-1.7	-0.2	-0.7	-1.3	-1.6	-1.4	-0.5	1.8	-0.0	0.1	-2.0	-0.0	-1.5	-1.3	-0.7	-1.4	-1.6	-1.7
Respiratory disease	1.2	2.6	9.4	1.9	0.3	2.0	1.8	1.7	-0.5	1.9	1.0	1.7	1.7	0.3	-1.9	1.5	0.9	1.7	-0.3	2.0	0.6	0.7	3.1	2.0	2.0
Chronotype (morning person)	1.2	2.8	5.4	-2.1	-2.1	-1.9	-1.9	-1.8	-0.7	-1.0	-1.9	-1.6	-2.2	0.9	2.3	0.2	-0.6	-2.0	0.9	-2.0	-1.3	-2.1	-2.1	-1.1	-2.1
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.2	1.7	1.6	1.1	1.8	1.4	0.3	-0.1	0.8	1.0	1.6	-0.3	-1.5	1.3	-0.5	1.2	-1.3	1.4	0.9	1.1	0.2	0.7	1.7
Heart attack	1.2	1.6	7.0	1.4	0.6	0.8	1.5	1.4	-0.7	1.1	1.2	1.5	1.3	-0.3	-1.1	1.1	1.6	1.3	0.4	1.6	2.7	1.0	0.7	0.7	1.4
Hair/balding pattern: Pattern 3	1.2	1.8	4.9	-1.1	-0.7	-0.9	-1.2	-1.8	-2.2	-0.7	-1.5	-1.5	-1.2	-0.6	1.3	-1.6	-1.2	-1.7	-0.4	-1.1	-0.8	-1.8	-1.2	-1.9	-1.1
Pulse wave reflection index	1.2	1.5	3.1	1.5	1.2	1.3	1.2	1.5	0.8	0.5	1.1	1.4	1.5	0.8	-1.3	0.2	0.8	1.8	-0.9	1.5	1.5	1.6	1.0	0.7	1.4
Medication: Ibuprofen	1.2	1.4	2.9	-1.1	-1.2	-1.5	-1.2	-1.2	-0.8	-1.6	-0.9	-1.3	-1.0	-0.0	1.1	-1.0	-1.5	-1.3	-0.5	-1.5	-1.3	-0.9	-1.7	-1.1	-1.1
Medication: Allopurinol	1.2	1.7	3.9	-1.5	-1.2	-1.3	-1.4	-1.6	-1.9	-1.2	-0.3	-1.4	-1.3	0.2	1.3	-0.3	0.6	-1.6	-0.9	-1.2	-2.0	0.2	-1.6	-1.5	-1.5
Pulse rate, automated reading	1.2	3.8	11.6	-2.4	-3.4	-1.3	-2.3	-2.3	-1.5	-1.2	-1.4	-2.3	-2.5	0.5	2.2	-0.4	-0.2	-2.9	2.4	-2.7	-0.3	-1.8	-1.1	0.1	-2.4
Illnesses of father: Heart disease	1.2	1.7	4.5	1.5	1.8	1.4	1.4	1.1	-0.8	-0.4	1.1	0.7	1.6	-1.7	-1.9	-0.6	-0.2	1.4	-2.1	1.2	0.5	1.9	0.8	0.1	1.5
Lupus	1.1	1.6	3.8	1.2	0.2	1.7	1.1	1.2	-0.9	1.9	1.5	1.8	1.3	0.2	-1.1	-0.2	1.3	0.8	1.7	1.4	0.7	1.4	1.6	1.6	1.1
Medication: Co-codamol	1.1	1.2	3.2	0.7	0.5	0.6	0.8	1.0	-1.2	1.4	1.6	1.3	1.0	0.0	-1.0	1.8	0.7	1.0	1.6	1.4	1.5	0.5	0.9	1.1	0.8
Serious illness, injury or assault to yourself	1.1	1.3	4.6	1.6	0.3	1.2	1.3	1.1	0.5	-0.8	0.2	0.5	1.5	-0.5	-1.2	-0.1	0.5	1.0	-2.1	1.8	0.2	2.0	0.9	0.1	1.5
Gout (self-reported)	1.1	1.5	4.7	-1.4	-1.7	-1.0	-1.6	-1.3	-1.4	-1.0	-1.1	-1.1	-1.3	1.2	0.9	-0.0	-0.3	-1.5	0.5	-1.6	-2.2	-0.6	-1.3	-0.6	-1.4
Heart disease (mother)	1.1	1.4	4.8	-0.6	-0.4	-1.0	-0.6	-0.9	0.4	-2.0	-1.3	-1.2	-0.5	-0.5	0.7	-1.9	-1.9	-0.5	-2.2	-0.3	0.2	-1.2	-1.6	-1.6	-0.5
Asthma (self-reported)	1.1	2.2	5.1	1.7	1.0	1.3	1.6	1.5	0.6	2.1	1.7	1.9	1.6	0.4	-1.6	0.8	1.6	1.6	0.3	2.3	0.7	1.4	1.8	1.4	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	4.7	-1.9	-0.5	-1.5	-1.8	-2.2	0.4	-1.5	-0.8	-1.8	-1.8	0.1	2.0	-1.5	-1.0	-2.1	-0.3	-1.9	-1.6	-1.0	-1.7	-1.7	-1.9
Average weekly champagne plus white wine intake	1.1	1.6	5.7	-1.5	-0.9	-0.5	-1.2	-1.1	-1.3	-1.3	-1.3	-1.3	-1.4	1.3	0.8	0.7	-0.9	-1.3	1.3	-2.1	-2.4	-0.9	-0.0	0.3	-1.4
Basal metabolic rate	1.1	6.3	11.2	3.2	1.8	3.0	3.0	3.1	0.6	2.0	1.1	3.1	3.2	1.7	-3.0	2.5	-0.5	3.3	0.4	2.9	1.9	-0.4	3.0	3.0	3.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	3.8	1.4	0.4	1.3	1.3	1.3	-0.8	-0.2	0.2	1.2	1.4	-0.1	-1.1	2.0	0.2	1.3	1.7	1.1	1.9	0.1	0.8	1.5	1.4
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.5	-0.9	-1.1	-1.0	-0.9	-1.0	1.3	-1.1	-0.7	-1.2	-1.0	-0.9	1.1	-0.9	-1.7	-1.0	-0.9	-1.3	-1.1	-1.9	-0.6	-1.3	-0.8
Father’s age at death	1.0	1.4	4.5	-1.3	-0.8	-1.3	-1.7	-1.2	-1.1	0.4	0.1	-0.8	-1.2	1.9	1.3	-2.1	0.1	-1.2	1.0	-1.0	-0.7	0.6	-1.4	-1.0	-1.4
Noisy workplace	1.0	1.2	3.6	0.8	0.3	1.6	0.8	0.8	-1.2	-0.2	0.9	0.7	0.8	-1.7	-1.3	1.5	1.9	1.1	0.1	0.7	1.7	0.5	1.2	1.2	0.8
Asthma	1.0	1.9	4.6	1.6	0.8	1.1	1.5	1.4	0.8	2.1	1.5	1.8	1.5	0.6	-1.5	0.8	1.4	1.5	0.4	2.2	0.5	1.2	1.6	1.3	1.6
Overall health rating	1.0	2.2	4.6	1.7	0.2	1.7	1.6	1.8	0.4	0.0	0.4	1.7	1.7	-0.7	-1.5	2.0	0.8	1.7	1.4	1.2	1.7	1.5	2.2	1.9	1.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	7.3	-0.7	0.4	0.2	-0.4	-0.1	-1.0	2.0	1.3	0.6	-0.6	-0.2	0.0	1.5	2.5	-0.3	2.7	-0.3	-0.3	0.8	0.4	1.0	-0.7
Whole body water mass	1.0	5.5	9.5	3.0	1.6	2.9	2.8	2.8	0.5	1.9	1.0	2.9	3.0	2.0	-2.7	2.3	-0.6	3.1	0.6	2.6	1.8	-0.5	3.0	2.9	3.1
Hearing aid user	1.0	1.1	2.6	0.9	1.0	0.9	1.6	1.1	-0.1	0.6	1.6	1.0	1.3	-0.4	-1.6	0.8	0.9	1.3	-1.2	1.1	0.5	0.6	1.2	0.3	1.0
Tinnitus: Yes, now most or all of the time	1.0	1.2	5.3	1.2	0.6	0.7	1.1	0.8	-1.0	1.1	1.5	1.4	1.3	1.0	-0.7	1.0	1.7	0.4	0.1	1.4	-0.2	2.3	0.5	0.7	1.0
Alcohol drinker status: Never	1.0	1.2	3.0	0.8	0.0	1.2	0.8	1.3	-0.0	1.1	1.2	1.3	1.0	-0.7	-1.0	0.8	1.7	1.1	1.2	0.6	0.4	1.7	1.3	1.6	0.9
Irritable Bowel Disease (IBD)	0.9	2.0	13.0	0.5	-0.7	0.6	0.2	0.0	0.6	2.4	3.0	1.3	0.5	-0.1	0.1	1.0	3.6	-0.3	2.3	0.4	-0.5	2.6	0.5	0.4	0.2
Ulcerative Colitis (UC)	0.9	1.7	4.7	-1.5	-2.2	-1.6	-1.6	-1.7	-0.7	-0.5	-0.2	-1.1	-1.5	-0.5	1.6	-0.1	1.1	-1.8	0.1	-1.0	-2.0	0.3	-1.5	-1.6	-1.6
Blood Platelet Count	0.9	10.3	17.4	4.0	2.1	4.0	3.9	3.9	-0.1	3.2	2.7	3.8	4.1	-0.2	-3.8	2.6	1.5	3.8	1.0	3.3	2.3	2.5	4.2	3.9	4.0
Lung FVC	0.9	4.5	11.9	-2.4	-0.8	-2.6	-2.6	-2.6	-1.3	-1.0	-0.4	-2.2	-2.2	-0.5	2.5	-3.4	-1.5	-2.2	-2.2	-2.0	-1.1	-0.6	-2.7	-3.2	-2.4
Current tobacco smoking	0.9	1.5	6.2	1.1	1.6	0.9	0.9	1.2	-0.5	1.6	0.9	1.4	1.1	-0.1	-1.1	0.6	1.7	1.0	1.7	1.2	2.5	1.2	0.4	1.2	1.1
Age when periods started (menarche)	0.9	2.1	5.5	1.2	2.2	1.6	1.0	1.6	-0.6	1.3	1.9	1.6	1.2	-0.7	-1.4	0.8	2.2	1.6	0.2	1.2	2.3	1.0	1.4	1.8	1.2
Multivitamins +/- minerals	0.9	1.2	5.5	1.2	2.3	0.7	1.2	0.9	-0.2	0.8	0.3	0.9	1.2	1.6	-1.2	0.7	-0.5	1.2	-1.1	1.5	0.9	-0.0	0.4	0.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.1	1.4	-0.3	1.4	1.2	1.3	-1.5	-0.2	-0.4	1.3	1.5	0.1	-1.1	1.7	0.2	1.2	1.7	0.8	1.0	0.6	1.1	1.7	1.4
Forced vital capacity (FVC)	0.9	3.4	11.3	-1.7	-0.7	-2.0	-2.0	-2.3	-0.3	-0.6	-0.3	-1.7	-1.7	1.0	2.1	-3.4	-1.8	-1.5	-2.2	-1.4	-0.7	-2.0	-2.2	-3.1	-1.8
Impedance of arm (right)	0.9	4.1	10.3	-2.5	-1.2	-2.0	-2.4	-2.2	-2.2	-0.9	-0.7	-2.2	-2.5	-3.2	2.2	-2.8	0.3	-2.2	-0.9	-2.0	-0.4	-0.4	-2.2	-2.6	-2.5
Hip circumference	0.9	3.9	7.7	2.6	2.1	1.9	2.7	2.6	0.5	1.2	0.8	2.3	2.7	0.4	-2.7	2.2	-0.1	2.8	-1.0	2.5	0.9	-0.2	1.9	1.8	2.8
Length of working week for main job	0.9	1.0	3.4	0.9	0.3	1.1	0.9	1.0	-0.6	-1.4	-0.8	0.5	0.9	0.3	-1.1	1.6	-0.6	1.0	1.2	0.7	0.7	-0.4	1.3	1.9	0.9
Medication: Paracetamol	0.9	1.5	4.7	-1.2	-2.2	-1.0	-1.5	-1.5	-0.6	-0.3	0.1	-1.0	-1.2	-1.5	1.6	-0.8	-1.3	-1.7	0.3	-1.0	-1.2	-0.7	-1.2	-1.5	-1.3
Migraine (self-reported)	0.9	1.2	11.8	-0.2	-0.5	0.7	-0.0	0.4	-0.3	1.3	1.1	0.3	-0.2	-0.6	0.3	0.2	1.7	-0.3	3.4	-0.7	1.0	0.7	1.1	1.8	-0.2
Whole body fat-free mass	0.9	5.2	8.9	2.9	1.4	2.8	2.7	2.7	0.5	1.9	0.8	2.8	2.9	1.9	-2.6	2.1	-0.8	3.0	0.5	2.5	1.7	-0.7	2.9	2.8	3.0
Illnesses of father: None of the above (group 1)	0.9	1.1	4.9	-1.1	-0.1	-0.9	-1.0	-0.9	-0.9	0.5	0.3	-0.6	-1.3	0.9	0.7	1.6	0.7	-1.2	2.2	-0.6	-0.5	-2.0	-0.5	0.3	-1.0
Average weekly beer plus cider intake	0.9	1.3	3.6	1.0	1.0	1.2	1.0	1.0	0.6	1.4	1.9	1.2	0.9	-0.1	-0.9	0.5	1.9	0.9	1.2	1.2	1.2	0.4	1.2	1.2	1.0
Bipolar Disorder (2018)	0.8	1.3	3.0	-1.3	-0.9	-1.4	-1.2	-1.2	-0.9	-0.9	-0.0	-1.1	-1.1	0.6	1.1	-1.3	1.1	-1.4	0.1	-1.4	-1.4	0.2	-1.7	-1.0	-1.4
Depressed Affect (Nagel 2018)	0.8	1.7	4.3	1.4	-0.0	1.6	1.3	1.5	-0.4	1.3	1.5	1.7	1.5	-1.0	-1.1	2.1	0.5	1.3	1.2	1.0	0.5	0.7	2.0	1.4	1.4
Reaction Time	0.8	1.5	10.4	1.0	1.9	1.2	1.1	1.1	0.1	1.1	0.4	0.7	1.1	-3.2	-1.3	-0.0	-0.9	1.4	-1.0	1.1	-0.4	-0.5	1.3	0.2	1.1
Neuroticism (2016)	0.8	1.2	5.2	-0.7	-2.3	-1.0	-0.7	-1.2	-2.0	-1.4	-1.5	-1.0	-0.5	0.5	1.5	0.6	-0.6	-1.3	-0.3	-0.4	-1.0	-0.4	-0.6	-1.0	-0.9
Ulcerative Colitis	0.8	1.2	2.2	-1.2	-1.2	-1.5	-1.2	-1.4	-0.3	-1.4	-0.2	-1.3	-1.2	-0.8	1.3	-0.5	0.9	-1.3	-0.3	-0.8	-1.0	0.2	-1.1	-1.5	-1.4
Leg fat-free mass (left)	0.8	4.3	7.5	2.6	1.3	2.6	2.4	2.5	0.3	1.7	0.9	2.7	2.6	1.7	-2.3	2.2	-0.4	2.7	0.6	2.3	1.5	-0.5	2.7	2.6	2.6
Leg predicted mass (left)	0.8	4.4	7.7	2.6	1.2	2.6	2.4	2.6	0.4	1.7	0.9	2.7	2.7	1.8	-2.4	2.2	-0.5	2.8	0.7	2.3	1.5	-0.5	2.7	2.6	2.7
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	8.3	-1.6	-0.4	-1.9	-1.9	-2.2	-0.4	-1.2	0.0	-1.7	-1.6	0.9	2.2	-2.6	-1.1	-1.6	-1.5	-1.3	-0.0	-1.3	-2.3	-2.9	-1.7
Trunk predicted mass	0.8	4.3	7.6	2.7	1.5	2.5	2.5	2.4	0.8	1.6	0.7	2.4	2.6	2.0	-2.4	1.8	-1.0	2.7	0.3	2.4	1.6	-1.0	2.6	2.4	2.8
Hair/balding pattern: Pattern 4	0.8	1.9	4.2	1.2	1.6	2.0	1.3	1.7	1.0	0.5	1.3	1.4	1.4	0.2	-1.9	0.5	-0.4	1.8	-0.0	1.0	2.0	0.9	1.8	2.0	1.3
Shortness of breath walking on level ground	0.8	0.9	5.7	0.5	0.1	0.7	0.4	0.8	-0.8	0.4	-0.4	0.7	0.4	1.1	-0.5	1.3	0.7	0.4	2.4	0.8	1.6	1.0	0.8	1.6	0.5
Supplements: Vitamin C	0.8	0.9	3.3	1.1	1.8	0.6	1.2	1.0	1.1	0.2	0.8	0.8	1.1	-0.4	-1.0	0.7	-1.0	1.2	-1.2	1.4	0.1	-0.0	0.6	0.0	1.1
Knee pain experienced in last month	0.8	1.2	7.5	-1.2	-1.5	0.0	-1.3	-0.6	0.4	0.6	-0.8	-0.1	-1.0	1.5	0.8	1.0	0.6	-0.7	2.7	-1.2	-0.5	-0.7	1.0	1.2	-1.2
Long-standing illness, disability or infirmity	0.8	1.3	3.2	1.6	-0.2	1.5	1.4	1.3	0.3	-0.5	0.3	0.8	1.5	1.1	-1.3	0.3	0.7	1.1	-0.1	1.0	0.4	1.8	1.6	1.3	1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	5.2	-0.6	-1.4	-1.1	-0.7	-0.5	-2.3	-0.1	-0.1	-0.4	-0.6	0.6	0.9	0.0	2.0	-0.8	1.0	0.0	-0.5	0.6	-0.8	-0.3	-0.8
Diastolic blood pressure, automated reading	0.8	2.4	7.0	-1.7	-1.6	-1.7	-1.8	-1.5	-0.7	-1.6	-2.1	-1.7	-1.7	0.4	1.1	-0.3	-1.3	-1.7	0.7	-2.0	-2.6	-1.7	-1.7	-1.1	-1.6
Pack years of smoking	0.8	1.2	2.9	1.2	-0.2	1.2	1.3	1.4	-0.6	1.1	0.0	1.3	1.1	0.3	-0.9	0.9	1.1	1.1	1.3	1.2	1.6	0.6	1.3	1.7	1.2
Verbal and Numeric Reasoning (VNR)	0.7	1.8	3.8	1.8	1.3	1.6	1.7	1.3	0.3	0.5	1.9	1.5	1.9	-0.5	-1.4	-0.7	-0.1	1.6	-1.6	1.7	1.3	0.8	1.0	0.3	1.8
Supplements: Zinc	0.7	0.8	2.7	1.0	1.7	1.2	1.1	0.5	-0.1	-0.9	0.5	0.1	0.9	-0.7	-1.0	-0.5	-0.6	0.8	-1.6	0.7	0.1	-0.0	1.4	0.2	1.0
Hand grip strength (right)	0.7	1.8	3.9	1.9	1.3	1.1	1.7	1.4	1.6	1.0	0.9	1.5	1.9	0.2	-1.1	0.6	-1.4	1.8	-0.7	1.7	1.4	-1.2	0.8	0.7	2.0
Supplements: Glucosamine	0.7	0.9	5.0	0.1	0.9	1.0	0.2	0.3	1.2	-0.1	1.1	0.2	0.1	2.2	-0.5	1.4	-0.7	0.1	1.2	-0.0	0.8	0.9	1.5	1.6	0.1
Nervous feelings	0.7	1.2	3.6	-1.3	-1.9	-1.8	-1.1	-1.1	-0.1	-1.2	-0.8	-1.1	-1.1	0.1	1.0	0.2	0.1	-0.9	0.5	-0.9	-1.8	-0.6	-1.5	-1.3	-1.3
Trunk fat-free mass	0.7	4.2	7.5	2.7	1.4	2.5	2.4	2.4	0.8	1.5	0.6	2.4	2.6	2.0	-2.4	1.7	-1.1	2.7	0.2	2.3	1.6	-1.1	2.5	2.4	2.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	7.0	-1.1	0.2	-1.6	-1.2	-1.8	0.6	-1.4	0.3	-1.6	-1.1	0.9	1.6	-2.6	-0.9	-1.1	-2.6	-1.1	-0.7	-1.4	-1.8	-2.7	-1.2
Impedance of arm (left)	0.7	3.1	7.5	-2.2	-0.9	-1.7	-2.1	-1.9	-2.2	-0.4	-0.5	-1.9	-2.2	-2.7	1.8	-2.4	0.3	-1.9	-0.5	-1.8	-0.8	-0.2	-1.8	-2.3	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	7.0	-0.8	-1.3	-0.9	-0.4	-0.8	-0.5	-1.9	-1.2	-1.0	-0.7	-1.0	0.8	-0.0	-1.0	-0.5	-0.2	-0.3	0.0	-2.6	-1.0	-1.0	-0.6
Medication: Ventolin 100micrograms inhaler	0.7	0.8	3.3	0.4	-0.3	0.9	0.2	0.7	-0.5	1.0	0.8	0.6	0.3	1.5	-0.7	1.2	1.7	0.5	1.1	0.3	0.6	0.6	1.4	1.8	0.4
Birth weight	0.7	1.5	11.0	-1.0	-1.1	-1.1	-0.9	-1.3	-0.1	-0.8	-1.8	-1.3	-1.0	0.1	0.9	-0.6	-1.5	-0.6	-0.8	-1.1	-0.7	-3.3	-1.0	-1.1	-0.9
Comparative height size at age 10	0.7	3.7	7.8	2.4	2.4	1.9	2.1	1.7	-1.5	2.1	1.4	2.1	2.3	-0.3	-1.9	0.1	-1.1	2.5	-2.7	2.8	1.6	-1.6	1.8	0.3	2.5
Family relationship satisfaction	0.7	0.9	4.8	-0.1	0.1	0.1	0.0	0.0	1.9	1.2	0.4	0.5	0.0	2.2	-0.1	1.5	1.3	-0.1	2.1	0.0	0.5	0.5	-0.1	0.8	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	4.0	0.5	0.2	1.2	0.6	1.0	-0.5	0.4	-0.4	0.9	0.5	0.4	-0.6	1.0	1.7	0.3	2.0	-0.2	0.3	1.4	0.8	2.0	0.3
Leg fat-free mass (right)	0.7	3.9	8.3	2.4	1.0	2.5	2.1	2.3	0.6	1.7	0.7	2.4	2.4	1.8	-2.0	2.1	-0.5	2.5	1.1	2.0	1.5	-0.8	2.9	2.6	2.4
Loneliness, isolation	0.7	0.9	4.4	0.9	-0.3	0.9	0.8	0.8	-0.1	0.3	1.4	1.1	1.0	-0.2	-0.4	2.1	1.0	0.7	0.6	1.0	1.3	0.8	1.2	0.8	0.8
Medication for cholesterol	0.7	1.0	4.8	-1.1	0.4	-1.2	-1.1	-1.0	-0.3	2.2	2.0	-0.1	-1.0	-0.6	0.9	-1.2	0.8	-0.6	0.8	-0.5	-0.2	-1.2	-0.4	-0.7	-1.1
Smoking status: Current	0.7	1.1	4.5	1.0	1.3	0.7	0.8	1.1	-0.8	1.4	0.6	1.1	0.9	-0.9	-0.8	0.6	1.1	0.8	1.4	0.9	2.1	0.6	0.2	1.1	1.0
Leg predicted mass (right)	0.7	3.9	8.4	2.3	1.0	2.5	2.1	2.3	0.5	1.7	0.8	2.4	2.4	1.7	-2.1	2.1	-0.5	2.5	1.1	2.0	1.5	-0.8	2.9	2.6	2.4
Ever taken oral contraceptive pill	0.7	0.7	3.3	0.9	1.0	0.2	1.0	0.3	-1.1	-0.5	-0.2	0.2	1.0	1.3	-1.1	0.3	0.8	0.5	-1.8	1.2	-0.3	0.7	0.2	-0.5	0.9
Number of operations (self-reported)	0.7	1.0	2.9	0.5	-0.0	0.8	0.2	0.5	-0.7	1.4	1.0	0.7	0.3	1.7	-0.3	0.6	1.7	-0.1	1.7	0.7	1.4	1.6	1.1	1.0	0.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	3.8	0.6	0.8	-0.1	0.7	0.5	0.9	-0.2	0.9	0.8	0.7	1.1	-1.0	0.4	1.5	0.7	-2.0	1.1	0.1	1.9	0.0	-0.2	0.6
Pain experienced in last month	0.7	1.2	7.8	-0.1	1.2	-1.5	-0.1	-0.4	-0.6	-1.3	-0.4	-0.7	-0.2	0.1	0.4	-1.5	0.2	-0.3	-2.8	0.3	-0.7	0.2	-2.3	-1.8	-0.1
Alzheimer’s Disease (including proxy)	0.6	0.8	1.7	1.0	1.1	0.6	1.0	0.7	0.8	0.1	0.9	0.7	1.1	0.7	-1.1	0.8	1.3	0.9	-0.7	1.3	-0.4	1.1	0.8	0.2	1.0
Body Mass Index (BMI) (2010)	0.6	0.8	2.1	1.2	0.7	0.9	1.2	0.8	-0.8	0.2	0.2	1.0	1.1	-1.2	-1.1	1.4	0.2	0.9	-0.7	1.3	0.1	0.3	0.4	-0.1	1.2
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.4	0.9	0.8	1.2	0.6	0.9	0.1	0.8	0.6	0.9	0.8	-0.6	-0.8	-0.5	-0.4	0.7	0.9	0.8	1.6	0.3	0.5	1.0	0.9
Medication for hormone replacement therapy	0.6	0.7	1.9	1.1	-0.2	1.0	0.9	0.6	-0.1	-1.4	-0.9	0.0	1.1	-1.1	-0.7	0.2	-0.9	0.5	-1.2	1.0	0.4	0.9	0.7	0.4	1.1
Vitamin and mineral supplements	0.6	0.8	4.4	-0.8	-2.0	-0.5	-1.0	-0.6	0.0	-0.4	-0.4	-0.4	-0.8	-0.8	1.1	-0.3	1.0	-0.9	2.1	-1.2	-0.6	0.5	-0.3	0.1	-0.9
Diabetes (self-reported)	0.6	1.0	2.9	1.1	0.0	1.3	0.9	0.9	0.1	0.6	0.3	0.9	0.9	1.4	-1.0	0.2	1.7	0.6	1.2	0.5	1.2	1.0	1.3	1.4	1.0
Medication: Ramipril	0.6	0.8	4.0	0.5	-0.7	0.8	0.3	0.6	-1.7	0.6	-0.7	0.8	0.4	0.1	-0.5	-0.2	1.7	0.2	0.6	0.5	1.6	2.0	0.8	1.0	0.4
Illnesses of siblings	0.6	0.8	7.6	-0.8	-0.4	-0.7	-0.5	-0.6	1.1	1.1	0.1	-0.3	-0.8	2.8	0.7	-1.1	-0.0	-0.6	-0.2	-0.8	-0.9	-0.5	-0.6	-0.4	-0.8
Happiness	0.6	0.7	2.9	-0.8	-1.7	-0.5	-1.1	-0.7	0.1	-1.1	-1.3	-0.7	-0.9	0.4	0.5	0.0	-0.9	-0.7	0.8	-1.0	0.3	-1.4	-0.9	-0.2	-0.7
Illnesses of mother	0.6	0.7	3.7	0.5	0.4	0.8	0.5	0.7	-0.3	1.9	1.6	0.9	0.4	0.0	-0.7	0.6	1.4	0.6	0.4	0.5	0.8	0.8	0.8	0.9	0.5
Blood clot in the leg (DVT)	0.6	0.7	1.8	1.0	0.9	0.9	0.8	0.8	0.3	0.9	0.6	0.8	0.9	1.2	-0.8	1.1	-0.4	0.7	-0.3	1.4	1.0	0.3	0.9	0.4	1.0
Forced vital capacity (FVC), Best measure	0.6	2.2	9.2	-1.0	0.1	-1.5	-1.2	-1.7	0.7	-0.9	0.1	-1.4	-0.9	1.0	1.4	-2.7	-1.4	-0.9	-3.0	-0.9	-1.0	-1.6	-1.7	-2.7	-1.1
Worry too long after embarrassment	0.6	1.1	7.3	-0.7	-2.7	0.0	-0.7	-0.5	-0.7	-0.8	-1.8	-0.7	-0.7	0.2	0.8	0.1	-1.3	-0.5	0.8	-1.3	-1.0	-1.5	1.0	0.5	-0.7
Medication: Seretide 50 evohaler	0.6	0.7	4.6	-0.6	0.2	-0.6	-0.6	-0.5	0.6	-1.3	-0.5	-0.8	-0.8	2.1	0.5	-0.9	1.1	-0.5	-1.0	-0.1	-0.5	0.7	-0.7	-0.8	-0.6
Number of full sisters	0.6	0.8	1.7	0.9	0.8	0.1	1.0	1.0	0.7	0.8	0.7	1.0	0.8	1.3	-1.1	0.1	1.3	1.2	-0.7	1.0	0.8	0.7	0.4	0.4	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	6.5	-0.4	-0.7	-0.7	-0.3	-0.7	0.8	-0.4	-0.0	-0.8	-0.4	-0.0	0.7	-0.9	-0.8	-0.4	-2.6	-0.4	-0.1	-1.0	0.1	-1.1	-0.4
Commuting to job workplace: Walk	0.6	0.6	2.8	0.5	0.1	1.1	0.4	0.8	-0.9	-0.1	0.7	0.8	0.4	-0.5	-0.6	0.8	0.9	0.4	1.0	-0.1	0.7	0.9	1.7	1.0	0.4
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	5.4	-1.2	-0.4	-0.7	-0.8	-0.6	-0.3	-0.4	-0.9	-0.6	-1.0	2.3	0.3	0.9	-0.8	-0.7	1.6	-1.3	-1.0	-0.5	-0.5	0.7	-1.0
Breast cancer (self-reported)	0.6	0.7	4.8	-0.7	-0.2	-0.6	-0.6	-0.6	-0.4	1.0	0.4	-0.1	-0.8	2.2	0.7	0.6	1.6	-0.8	1.1	-0.1	0.2	0.4	-0.5	-0.2	-0.7
Commuting to job workplace: Public transport	0.6	0.8	2.1	-1.0	-0.2	-0.1	-1.2	-0.8	0.7	-0.6	-1.0	-1.1	-1.2	0.2	0.5	-0.9	-1.4	-1.0	-0.0	-1.4	-0.8	-1.1	-0.4	-0.6	-0.9
Eye problems/disorders: Glaucoma	0.6	0.7	1.6	-1.0	-1.3	-0.1	-1.2	-0.8	1.0	0.5	0.8	-0.7	-1.1	-0.1	1.2	-0.4	-0.1	-1.0	0.7	-0.5	1.1	0.1	-0.5	0.1	-1.1
Medication: Paracetamol	0.6	0.9	2.4	-0.8	-1.6	-0.6	-1.0	-1.0	-0.6	-0.5	0.3	-0.8	-0.9	-1.2	1.0	-0.7	-1.1	-1.2	-0.4	-1.0	-0.5	-0.9	-1.0	-1.3	-0.8
Myopia	0.6	0.9	7.6	-0.6	1.2	-0.4	-0.5	-0.4	2.8	0.8	-0.2	-0.6	-0.7	1.2	0.2	-1.8	-0.4	-0.4	0.4	-0.5	-0.3	-0.7	-0.7	-0.5	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.2	1.0	0.8	0.6	0.9	0.7	0.3	0.7	0.4	0.8	0.9	1.3	-0.9	1.0	-0.5	0.8	-0.8	1.5	1.2	-0.0	0.6	0.2	1.1
Bipolar Disorder or Schizophrenia	0.5	1.3	4.0	-1.2	-0.2	-1.3	-1.3	-1.2	-1.1	-0.0	0.5	-0.6	-1.1	-1.5	1.0	-2.0	1.0	-0.9	-0.4	-1.3	-0.6	-0.4	-2.0	-1.8	-1.3
Major Depression (MDD)	0.5	0.6	2.4	-0.1	-1.0	-0.8	-0.2	-0.1	-0.3	-1.5	-1.3	-0.6	-0.1	0.6	0.6	-0.5	-0.4	0.0	-0.9	-0.6	-1.3	-0.9	-1.0	-0.4	-0.1
Ovarian Cancer	0.5	0.6	2.2	-0.5	-0.9	-0.6	-0.6	-0.6	-0.4	-1.5	-1.5	-0.8	-0.6	-1.0	0.6	0.5	-0.4	-0.8	0.3	-0.6	-0.4	-1.2	-1.2	-0.3	-0.4
Frequency of depressed mood in last 2 weeks	0.5	0.8	1.7	1.1	-0.4	1.1	1.0	0.9	-0.0	-1.0	-0.5	0.6	1.2	0.7	-0.7	1.0	-0.7	1.0	0.4	1.0	1.3	0.1	0.9	0.9	1.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	4.2	-0.0	-0.4	-0.6	0.1	-0.4	0.5	-2.0	-0.6	-0.8	0.1	0.3	0.2	-0.2	-0.5	-0.4	-1.6	0.6	0.2	1.6	-1.1	-1.2	-0.1
Pack years adult smoking proportion	0.5	0.8	2.1	1.0	-0.5	0.9	1.0	1.0	-1.0	0.9	-0.1	1.1	0.9	-0.4	-0.5	0.6	1.1	0.8	1.3	1.0	1.5	0.5	0.9	1.3	0.9
Taking other prescription medications	0.5	0.8	5.8	-0.2	-1.5	-0.1	-0.1	-0.3	0.6	-1.7	-0.9	-0.9	-0.2	0.2	0.0	-1.8	-0.4	-0.2	-2.4	-0.3	0.0	-0.0	-0.2	-0.6	-0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	2.4	-0.8	-0.2	-0.2	-0.9	-0.8	1.6	0.1	-0.4	-0.7	-0.7	-1.0	0.6	-0.7	-1.3	-0.5	-0.4	-0.6	0.2	-0.4	-0.5	-1.2	-0.8
Qualifications: None of the above	0.5	1.1	6.2	0.1	-0.4	-0.5	0.4	0.6	-1.7	2.5	1.6	1.2	0.2	0.0	-0.6	1.7	1.8	0.4	0.6	0.7	-1.2	0.7	0.3	0.4	0.1
Financial difficulties in last 2 years	0.5	0.7	5.7	-0.2	-0.7	-0.8	-0.3	-0.7	-0.3	0.0	-0.3	-0.2	-0.1	-2.4	1.3	-1.2	-0.7	-0.7	0.0	0.1	0.4	-0.5	-1.0	-1.6	-0.3
Fluid intelligence score	0.5	0.9	3.1	1.2	0.8	0.7	0.8	0.4	-1.1	-0.1	1.5	0.6	1.3	-0.6	-0.6	-1.5	-1.1	0.7	-1.8	1.3	0.0	0.9	0.1	-0.5	1.1
Neuroticism score	0.5	1.0	7.8	-0.7	-2.8	-0.4	-0.5	-0.6	-0.6	-1.0	-1.0	-0.7	-0.5	-0.9	0.7	1.2	-1.5	-0.5	0.6	-0.9	-0.9	-1.4	0.4	-0.2	-0.7
Falls in the last year	0.5	0.6	2.5	0.3	-0.0	0.3	0.4	0.8	-0.3	0.8	0.5	1.0	0.4	0.6	-0.5	1.6	0.8	0.5	1.5	0.5	0.0	1.5	0.6	1.2	0.3
Number of live births	0.5	0.7	4.7	-0.8	0.1	-0.7	-0.6	-0.5	0.3	0.0	-0.5	-0.7	-0.8	0.5	0.4	0.3	-2.2	-0.6	0.4	-0.9	0.1	-1.9	-0.9	0.1	-0.6
Depression (self-reported)	0.5	0.6	3.0	-0.1	-0.7	-0.2	-0.1	0.0	-1.5	-1.7	-1.7	-0.5	-0.0	-0.4	0.0	-0.5	-0.9	-0.1	-0.1	-0.0	-1.2	-0.7	-0.7	-0.2	-0.1
Prospective memory result	0.5	0.6	3.9	-0.1	-0.8	0.6	-0.1	0.1	-0.4	0.3	-0.2	0.1	-0.2	-0.3	0.0	2.0	1.3	0.0	1.5	-0.4	1.4	0.5	0.8	1.2	-0.2
Number of children fathered	0.5	0.6	1.9	-0.6	-1.1	-1.2	-0.7	-0.8	0.2	-1.4	-0.7	-1.0	-0.5	0.0	0.6	-0.8	-0.5	-1.0	-0.6	0.6	-0.2	-0.0	-1.2	-0.7	-0.6
Mean time to correctly identify matches	0.5	1.0	4.0	0.7	1.9	1.0	0.8	0.8	0.0	0.9	0.8	0.5	0.8	-2.0	-1.3	0.4	-1.0	1.2	-0.8	1.0	-0.4	-0.5	1.4	0.3	0.9
Chest pain or discomfort	0.5	0.7	3.3	0.4	-0.4	0.8	0.3	0.7	-0.2	0.8	-0.2	1.0	0.5	0.5	-0.8	0.4	0.2	0.8	1.6	0.3	0.2	1.1	1.8	1.5	0.4
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.3	0.7	0.6	-0.1	0.9	0.6	0.8	0.3	0.2	0.5	0.8	1.3	-0.5	0.9	0.5	0.8	0.4	1.5	1.5	0.6	-0.0	0.2	0.7
Diabetes diagnosed by doctor	0.5	0.9	2.0	1.0	0.4	1.4	0.9	1.0	0.6	0.2	-0.1	0.8	0.8	1.2	-1.2	0.4	1.0	0.9	0.9	0.4	1.3	0.8	1.4	1.3	1.1
Miserableness	0.5	0.9	3.2	0.4	-1.5	1.4	0.4	0.6	-0.4	1.0	0.2	0.8	0.5	-1.0	-0.1	1.4	-0.1	0.4	1.8	-0.2	-0.6	-0.4	1.8	1.3	0.4
High cholesterol (Self-reported)	0.5	0.8	4.0	-0.9	-1.1	-1.3	-0.6	-0.7	-0.5	-2.0	-1.1	-0.9	-0.8	0.2	0.4	1.1	-1.1	-0.7	-0.3	-0.8	-0.6	-0.8	-1.3	-0.6	-0.7
Medication: Atorvastatin	0.5	0.7	2.6	-0.9	-0.9	-0.8	-1.1	-0.8	-0.4	-0.2	-0.9	-0.7	-0.9	0.9	0.7	-1.6	-0.9	-0.7	-0.1	-1.0	-0.3	-0.8	-0.6	-0.2	-0.9
Age started oral contraceptive pill	0.5	0.6	1.8	0.6	1.1	0.7	0.9	0.6	0.8	-0.4	0.0	0.3	0.7	-1.1	-1.0	0.5	-1.3	0.7	-1.1	0.9	0.0	-0.2	1.0	0.4	0.8
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.5	-0.9	1.3	-1.5	-0.7	-1.4	1.5	0.6	1.0	-0.9	-0.8	0.6	1.4	-1.1	-0.6	-1.1	-0.9	0.1	-0.7	-1.2	-1.7	-1.9	-1.0
Alcohol drinker status: Previous	0.5	0.6	1.7	0.8	0.2	0.7	1.1	0.9	-0.1	0.0	-0.2	0.6	0.8	-1.1	-0.7	1.3	-0.9	0.6	0.4	0.6	-0.4	0.1	1.0	1.1	0.9
Schizophrenia (2018)	0.4	0.7	5.7	-0.5	0.5	-0.6	-0.7	-0.6	-0.6	0.7	0.6	0.1	-0.5	-2.4	0.3	-1.5	0.3	-0.0	-0.7	-0.5	0.3	-0.8	-1.1	-1.5	-0.5
Mean Putamen Volume	0.4	0.5	4.4	-0.2	-0.4	0.1	-0.2	-0.3	-0.2	1.0	1.3	0.1	0.1	-1.0	-0.0	1.0	-2.1	-0.2	0.2	0.4	-0.9	-0.5	0.6	-0.1	-0.1
Schizophrenia (2014)	0.4	0.8	5.9	-0.6	0.1	-0.5	-0.7	-0.6	-1.2	1.0	0.7	0.1	-0.6	-2.4	0.3	-1.7	0.4	-0.3	-0.3	-0.5	0.4	-0.3	-1.1	-1.1	-0.6
Triglycerides	0.4	0.6	3.4	0.8	0.6	0.7	0.8	0.6	-0.1	-0.0	0.8	0.7	0.6	-0.3	-1.2	1.8	1.1	0.9	-0.1	1.0	-0.5	0.3	0.8	0.6	0.8
Hand grip strength (left)	0.4	1.1	2.2	1.3	1.5	0.7	1.1	1.0	1.4	0.6	0.5	1.1	1.3	1.3	-0.8	0.9	-1.0	1.3	-0.7	1.4	0.9	-1.1	0.2	0.4	1.4
Average weekly spirits intake	0.4	0.5	1.5	-1.0	-0.4	-0.6	-1.0	-0.5	0.4	-1.0	0.1	-0.7	-1.0	1.2	0.6	0.4	0.6	-0.5	0.8	-0.4	1.2	-0.3	-0.2	0.2	-1.0
Medication: Metformin	0.4	0.6	3.2	0.5	-0.2	1.2	0.4	0.5	0.5	0.0	-1.2	0.4	0.4	0.3	-0.4	0.5	0.0	0.2	1.8	-0.0	1.3	0.6	1.2	1.0	0.5
Diabetes (father)	0.4	0.5	2.7	-0.6	-0.9	-0.5	-0.7	-0.5	-1.0	0.4	-0.6	-0.2	-0.7	-0.6	1.0	-1.6	0.1	-0.5	-0.9	-0.2	0.2	0.3	-0.5	-0.8	-0.8
Townsend deprivation index at recruitment	0.4	0.6	2.9	0.1	-0.3	0.3	0.3	0.3	-0.6	1.5	1.5	0.6	0.3	-0.1	-0.5	1.4	1.1	-0.3	1.7	0.0	-0.4	1.0	0.3	0.8	0.0
Average weekly fortified wine intake	0.4	0.5	4.3	0.0	0.4	-0.0	0.1	-0.1	2.1	-0.8	0.3	-0.1	0.2	1.4	0.0	-0.9	0.2	0.1	-1.2	0.2	0.5	0.7	0.1	-0.3	0.0
Fed-up feelings	0.4	0.7	2.8	0.8	-0.8	0.7	0.9	0.6	0.2	0.7	1.4	1.0	1.0	-1.0	-0.3	1.7	0.4	0.5	0.5	0.5	0.2	1.0	1.0	0.4	0.6
Stomach or abdominal pain in last month	0.4	0.5	4.0	-0.4	-1.3	0.1	-0.4	-0.3	0.4	0.1	-0.6	-0.2	-0.4	-0.6	0.7	0.5	-0.4	-0.6	2.0	-0.7	-0.4	-0.6	0.1	0.4	-0.5
Medication: Simvastatin	0.4	0.5	5.6	-0.1	-0.3	-0.0	0.1	0.2	-0.7	-2.4	-0.6	-0.5	-0.2	-0.8	-0.5	1.3	-0.4	-0.0	-0.9	-0.4	0.6	0.2	-0.6	-0.0	0.0
High blood pressure (siblings)	0.4	0.6	8.8	-0.0	-0.8	-0.1	-0.3	-0.4	-0.6	-0.6	-0.6	-0.6	-0.2	-3.0	0.3	-0.0	-0.9	-0.3	-0.4	0.0	0.2	-0.9	-0.3	-0.7	-0.0
Eye problems/disorders: None of the above	0.4	0.5	1.1	-0.8	-0.1	-1.0	-0.9	-0.9	-0.2	0.3	0.3	-0.7	-0.7	0.0	0.8	-0.7	-0.5	-0.7	0.8	-0.5	0.1	-1.0	-0.6	-1.0	-0.8
Emphysema/chronic bronchitis	0.4	0.4	2.0	-0.4	-1.4	-0.2	-0.6	-0.5	-0.9	-0.7	-0.4	-0.8	-0.6	-0.5	0.5	0.1	-1.0	-0.5	-0.2	-0.2	-0.2	-1.3	0.3	-0.0	-0.4
Medication for pain relief, constipation, heartburn	0.4	0.6	4.2	0.6	2.0	0.7	0.8	0.9	0.6	-0.3	0.2	0.6	0.7	0.6	-0.9	0.3	0.8	1.2	0.1	0.7	0.9	-0.1	0.7	0.9	0.7
Had major operations	0.4	0.5	1.3	-0.7	-1.1	-0.9	-1.0	-0.6	-0.6	-0.3	-0.2	-0.9	-0.9	0.8	0.8	-1.1	-0.4	-0.9	0.4	-0.5	-0.4	0.4	-0.3	-0.5	-0.8
Smoking status: Previous	0.4	0.6	4.5	-0.4	-0.4	-0.4	-0.2	-0.4	-0.4	-0.3	-0.4	-0.4	-0.3	2.1	-0.3	0.4	-0.2	-0.3	-0.5	-0.2	-2.0	-1.3	-0.4	-0.2	-0.3
Friendships satisfaction	0.4	0.5	2.2	0.2	-1.3	0.4	0.2	-0.0	-0.8	0.0	-0.8	0.3	0.3	1.2	-0.0	1.2	0.4	-0.2	1.5	0.1	0.9	0.1	0.3	0.8	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.6	-0.6	-1.1	-0.1	-0.9	-0.7	-0.7	0.7	1.3	-0.3	-0.6	-1.3	0.4	-0.3	0.4	-0.4	1.1	-0.1	0.3	-0.1	0.4	-0.5	-0.6
Guilty feelings	0.4	0.6	4.8	0.0	-2.2	0.7	-0.0	-0.1	-0.5	0.4	-0.1	0.2	0.2	-1.6	0.2	0.7	-0.1	-0.2	1.2	-0.5	-0.3	0.4	1.2	0.6	-0.1
Mother’s age at death	0.4	0.5	1.4	-0.7	-0.2	-0.5	-0.8	-0.6	-0.7	-0.4	-0.3	-0.7	-0.6	0.9	0.9	-0.8	-1.1	-0.8	0.5	-1.1	-1.2	0.1	-0.2	-0.2	-0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.2	-0.1	0.3	0.7	-0.1	0.1	0.5	0.7	1.4	0.0	-0.2	0.7	-0.1	1.1	-0.1	-0.4	1.5	-0.6	0.7	0.2	0.8	1.1	-0.2
Medication: Bendroflumethiazide	0.4	0.7	2.0	0.7	0.6	0.6	0.7	0.9	-0.8	1.3	0.5	1.0	0.7	-0.4	-1.1	-0.7	0.8	0.9	-1.0	0.9	0.5	1.4	0.3	0.3	0.7
Medication: Lisinopril	0.4	0.5	2.3	0.7	-0.2	0.3	0.7	0.5	-0.6	-0.9	-1.2	-0.1	0.6	-0.3	-0.9	0.7	-1.5	0.8	-1.0	0.4	0.1	-1.0	0.6	0.2	0.8
Commuting to job workplace: Cycle	0.4	0.5	2.5	-0.5	-0.7	0.1	-0.5	-0.4	1.0	0.4	1.3	-0.2	-0.3	-1.6	0.7	0.1	1.2	-0.5	-0.2	-0.9	-0.7	0.4	0.0	-0.4	-0.6
Intelligence (Savage-Jansen 2018)	0.3	0.8	6.6	0.3	0.1	0.8	0.3	-0.1	-1.2	-0.6	-0.6	-0.2	0.4	-1.9	-0.1	-1.6	-2.6	0.0	-0.5	-0.1	-0.3	-1.2	0.9	-0.1	0.3
Neuroticism (Nagel 2018)	0.3	0.8	3.3	0.7	-1.2	0.8	0.6	0.7	-1.5	-0.1	0.3	0.8	0.9	-1.0	-0.4	1.8	-0.3	0.8	0.9	0.3	-0.5	-0.2	1.4	0.8	0.7
Breast Cancer	0.3	0.8	6.3	-0.8	-0.3	-0.3	-0.9	-0.7	0.5	-2.5	0.0	-1.4	-0.8	-0.8	0.3	-0.2	-1.0	-0.4	-1.4	-0.5	0.1	-1.0	-0.3	-0.5	-0.7
Prostate Cancer	0.3	0.4	3.8	-0.0	0.3	-0.3	-0.1	-0.3	1.1	0.6	0.7	0.0	-0.0	1.9	0.6	-0.9	-0.2	-0.3	0.1	0.2	0.3	1.0	-0.1	-0.6	-0.2
Fasting Glucose	0.3	0.3	1.6	-0.8	-0.7	-0.3	-0.7	-0.4	0.1	-0.3	-0.2	-0.4	-0.7	-1.0	0.5	0.2	-0.6	-0.3	0.8	-0.4	-0.2	-1.2	0.2	0.0	-0.7
Type 2 Diabetes (T2D) (2012)	0.3	0.3	3.3	0.0	0.3	-0.5	-0.1	0.0	1.1	-0.1	0.2	0.2	-0.4	0.4	-0.0	0.7	0.2	-0.2	0.4	-0.4	-1.8	0.9	-0.5	-0.2	-0.1
Smoking Status	0.3	0.7	2.1	0.7	1.2	0.5	0.6	0.7	-1.0	1.0	0.8	0.7	0.7	1.5	-1.0	1.1	0.9	0.7	0.6	0.9	0.8	-0.3	0.3	1.0	0.8
Angina	0.3	0.4	2.3	0.2	-1.1	0.1	0.1	0.2	-1.5	0.2	-0.4	0.2	0.2	-1.3	-0.2	-0.6	-1.3	0.5	-0.7	-0.2	0.3	-0.1	0.6	-0.4	0.3
Diabetes (mother)	0.3	0.3	2.1	-0.0	-0.4	-0.4	-0.2	-0.2	-1.5	-0.0	-0.4	0.0	-0.1	-0.8	0.5	-0.3	1.2	-0.4	1.1	-0.0	0.5	0.0	-0.7	-0.2	-0.1
Severe depression (siblings)	0.3	0.4	2.6	-0.2	0.1	-0.7	0.0	-0.5	1.6	0.1	0.6	-0.2	0.0	-0.3	0.4	-0.7	-0.0	-0.6	-0.1	-0.2	-1.1	0.6	-0.8	-0.9	-0.3
High blood pressure	0.3	1.0	3.2	0.7	-1.2	1.4	0.5	1.1	-1.1	-0.9	-1.1	0.6	0.6	-0.4	-1.2	0.9	0.5	0.8	0.9	-0.3	0.1	1.0	1.7	1.8	0.7
High blood pressure (mother)	0.3	0.5	1.8	-0.8	-0.9	-0.6	-0.7	-0.5	1.0	-0.5	-0.6	-0.5	-0.7	0.5	0.4	-0.5	-1.3	-0.4	0.2	-0.9	-0.4	-0.9	-0.4	-0.1	-0.8
Past tobacco smoking	0.3	0.5	2.8	0.4	0.0	0.5	0.2	0.4	0.7	0.2	0.5	0.5	0.3	-1.3	0.4	-0.6	0.5	0.3	0.5	0.3	1.6	1.7	0.6	0.4	0.2
Hearing difficulty/problems with background noise	0.3	0.4	4.5	0.3	-0.3	-0.1	0.4	0.1	-0.5	0.7	0.6	0.5	0.4	2.1	-0.3	0.4	0.5	-0.2	1.0	0.2	-0.3	0.8	0.6	0.8	0.2
Hair/balding pattern: Pattern 2	0.3	0.3	1.9	0.2	-0.2	-0.8	0.5	0.0	1.1	0.3	0.5	0.1	0.3	0.1	-0.1	0.3	1.4	-0.1	-0.2	0.7	-0.5	1.2	-0.6	-0.5	0.2
Time employed in main current job	0.3	0.3	2.4	0.0	0.4	-0.3	0.2	0.4	-1.0	0.2	-0.4	0.2	0.1	-0.1	-0.6	0.1	-0.1	0.7	-1.5	0.0	-0.6	-0.2	-0.8	-0.7	0.1
Worrier / anxious feelings	0.3	0.6	3.3	-0.3	-1.8	-0.9	-0.1	-0.4	-1.2	-1.0	-1.0	-0.2	-0.2	-0.0	0.6	1.2	0.1	-0.2	0.0	-0.4	-1.5	-0.4	0.1	-0.5	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.4	-0.2	-0.3	-1.1	-0.3	-0.5	0.3	0.2	0.3	-0.2	-0.3	0.6	0.5	-0.9	-0.2	-0.2	-0.6	-0.3	0.0	-0.3	-1.1	-1.2	-0.3
Exposure to tobacco smoke at home	0.3	0.4	3.1	0.4	0.4	0.3	0.5	0.3	-1.8	0.3	0.7	0.6	0.5	-1.6	-0.1	0.2	-0.2	0.3	0.1	0.6	0.0	0.2	0.3	-0.0	0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	4.0	-0.1	0.3	0.1	-0.1	-0.0	2.0	0.1	0.9	-0.1	-0.0	0.3	-0.4	1.6	-0.0	0.1	0.2	-0.3	-0.3	-0.8	0.1	0.3	0.0
Loud music exposure frequency	0.3	0.3	1.4	0.4	0.7	0.4	0.4	0.7	0.5	0.1	0.0	0.6	0.4	0.8	-0.6	0.8	0.4	0.6	-0.1	0.7	1.2	-0.3	-0.2	0.6	0.5
Headache pain in last month	0.3	0.6	2.4	-0.6	-1.6	0.5	-0.7	-0.3	1.3	-0.5	0.4	-0.5	-0.6	-0.6	0.8	0.4	-0.5	-0.7	1.5	-0.8	0.6	-0.2	0.3	1.1	-0.6
Glaucoma (self-reported)	0.3	0.4	1.3	-0.8	-1.0	0.0	-0.7	-0.7	0.5	0.3	0.5	-0.7	-0.8	-0.2	1.2	-0.2	-0.2	-0.8	0.1	-0.2	1.1	0.0	-0.2	-0.2	-0.8
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.3	0.0	-0.3	0.2	0.3	0.2	1.3	0.3	-0.9	0.2	0.1	-0.3	0.3	1.0	-0.1	0.0	1.3	-0.1	-1.5	-0.2	0.2	0.6	0.0
Exposure to tobacco smoke outside home	0.3	0.4	1.7	-0.1	-0.2	0.1	-0.1	0.2	-0.0	1.3	0.7	0.3	-0.1	-0.7	0.1	0.8	-0.6	0.2	1.3	-0.7	-0.3	-1.2	0.3	0.3	-0.1
Comparative body size at age 10	0.3	0.9	6.0	0.5	0.8	0.9	0.6	0.4	0.6	-1.0	-0.6	0.1	0.5	-0.8	-0.6	0.8	-2.1	0.8	-1.1	0.6	0.9	-2.4	1.1	0.1	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.8	0.3	1.3	-0.2	0.1	0.1	-0.4	0.6	0.4	0.3	0.2	1.1	-0.4	0.7	0.1	0.3	-0.5	0.0	-1.4	-0.3	0.0	-0.2	0.3
Health satisfaction	0.3	0.4	2.7	0.5	0.2	0.3	0.3	0.6	1.6	0.6	0.1	0.7	0.3	0.4	-0.6	0.3	-0.2	0.5	0.5	0.5	1.6	0.2	0.4	0.4	0.5
Neck or shoulder pain in last month	0.3	0.4	1.7	-0.4	-1.3	0.4	-0.2	-0.3	0.8	0.9	-0.2	-0.2	-0.2	0.4	0.5	0.5	-0.9	-0.6	0.5	-0.4	-1.0	0.2	1.3	0.4	-0.4
Medication: Blood pressure	0.3	0.6	2.8	0.4	-0.8	1.0	0.5	0.9	-0.6	0.2	-0.3	0.6	0.4	-0.5	-1.0	0.9	1.3	0.8	-0.0	-0.1	-0.5	0.8	1.7	1.2	0.4
Angina (self-reported)	0.3	0.4	3.0	0.2	-1.3	0.1	0.1	0.2	-1.7	0.2	-0.5	0.2	0.3	-1.0	-0.3	-0.6	-1.2	0.4	-0.6	-0.1	0.4	0.1	0.6	-0.3	0.3
Suffer from ‘nerves’	0.3	0.5	2.4	0.5	-0.9	0.3	0.4	0.5	0.6	-1.3	-0.1	0.2	0.6	0.9	0.0	1.5	-0.4	0.3	1.1	0.7	0.2	-0.4	0.7	0.6	0.4
Leg pain on walking	0.3	0.3	1.4	-0.1	-0.3	-0.1	-0.2	0.0	-0.5	-0.3	-1.1	0.1	-0.3	0.4	0.2	1.0	-0.7	-0.1	1.2	0.3	1.2	-0.6	0.2	0.7	-0.1
Hypertension (Self-reported)	0.3	1.0	3.4	0.6	-1.5	1.4	0.3	1.0	-1.0	-0.3	-1.0	0.7	0.5	-0.7	-1.1	1.0	0.6	0.7	1.3	-0.5	0.2	0.9	1.6	1.8	0.6
Back pain experienced in last month	0.3	0.4	2.8	0.1	-0.5	0.4	-0.0	0.4	0.3	-0.2	0.5	0.4	0.2	1.7	-0.3	0.8	-0.2	0.3	1.4	0.1	0.7	0.5	0.7	1.0	0.1
Mineral and other dietary supplements	0.3	0.4	2.0	0.7	-1.4	0.4	0.3	0.6	-0.8	-0.3	-1.0	0.5	0.5	-1.0	0.0	0.6	0.6	0.4	0.9	0.4	-0.2	0.3	0.1	0.3	0.6
Number of self-reported non-cancer illnesses	0.3	0.6	1.7	0.8	-0.7	1.0	0.6	0.7	-0.1	-1.3	-0.8	0.1	0.6	-1.0	-0.9	-0.1	-0.7	0.7	-0.3	0.1	0.2	0.1	1.3	0.9	0.9
Medication: Blood pressure	0.3	0.5	2.5	0.7	-0.1	1.0	0.9	1.0	0.0	-0.5	-1.6	0.6	0.7	0.6	-1.1	0.7	-0.5	0.9	0.1	0.2	0.4	0.4	0.6	0.7	0.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	3.8	0.1	1.9	0.2	0.4	0.1	1.0	0.6	1.2	0.2	0.1	-0.3	-0.3	0.1	-0.4	0.4	-0.8	0.1	-0.0	-0.6	0.8	-0.0	0.2
Fractured/broken bones in last 5 years	0.3	0.4	1.8	0.0	-0.4	0.1	-0.3	0.1	-0.5	1.2	1.3	0.3	-0.1	-0.2	-0.1	-1.0	0.8	0.2	-0.2	0.5	1.1	1.1	-0.2	0.2	-0.0
Cholesterol lowering medication	0.3	0.4	3.5	0.1	-0.8	-0.0	-0.0	0.2	-0.9	-1.9	-1.0	-0.2	0.0	0.1	-0.2	1.0	-1.0	-0.0	-0.2	-0.3	-0.3	0.9	-0.5	0.1	0.1
Basal cell carcinoma (self-reported)	0.3	0.4	1.9	-0.4	-0.5	-0.3	-0.5	-0.5	-0.7	0.9	0.4	0.0	-0.4	0.3	0.9	-0.0	1.4	-0.6	1.3	-0.2	-0.5	0.4	0.2	-0.0	-0.5
Impedance of whole body	0.3	1.4	9.6	-1.0	0.0	-0.9	-0.8	-0.8	-1.8	0.4	0.5	-0.8	-1.0	-3.1	0.7	-1.8	1.0	-0.9	-0.7	-0.6	0.1	1.0	-1.3	-1.5	-1.0
Worry (Nagel 2018)	0.2	0.5	2.6	0.0	-1.5	-0.5	0.0	0.1	-1.1	-1.6	-1.0	-0.1	0.1	-0.1	0.2	1.5	-0.4	0.3	0.6	0.2	-0.8	-0.5	-0.0	-0.0	0.0
Coronary Artery Disease (CAD)	0.2	0.3	0.8	0.4	0.1	0.8	0.3	0.5	0.7	0.3	0.2	0.8	0.1	-0.9	-0.2	0.3	0.5	0.5	0.9	-0.2	0.0	0.0	0.8	0.7	0.3
HbA1C	0.2	0.2	1.2	0.3	-0.1	0.1	0.1	-0.2	0.5	-0.6	-1.0	-0.2	-0.0	0.9	0.0	0.2	-0.2	-0.4	0.3	0.3	-1.1	-0.0	0.1	0.4	0.2
Height	0.2	3.0	11.2	2.0	0.6	2.0	1.9	1.7	-0.5	1.3	0.2	1.8	2.0	0.8	-1.8	0.3	-0.2	2.3	-0.5	2.7	3.3	-2.3	1.9	1.3	2.1
Waist Hip Ratio (WHR)	0.2	0.8	5.8	0.2	-0.3	0.9	-0.2	0.2	0.8	2.4	1.4	0.7	0.2	0.1	-0.2	0.6	0.9	-0.2	1.6	-0.5	0.0	1.5	0.4	0.9	0.1
Systolic Blood Pressure	0.2	0.9	6.5	-0.8	0.3	-0.0	-0.5	-0.1	-1.3	0.0	-1.4	-0.3	-0.9	-0.7	-0.1	0.3	0.7	-0.8	2.6	-1.7	-0.9	0.0	-0.2	0.6	-0.8
Cardiovascular Disease	0.2	0.8	4.6	-0.5	-2.1	0.2	-0.6	-0.0	-1.7	-0.1	-1.0	-0.0	-0.5	-0.5	-0.3	0.8	0.7	-0.4	1.5	-1.3	-0.5	0.6	0.5	0.9	-0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.8	0.6	-0.2	0.7	0.5	0.7	0.6	0.2	-0.7	0.7	0.5	-0.1	-0.7	0.0	0.5	0.6	0.9	0.1	0.5	0.5	0.6	0.9	0.7
Neuroticism	0.2	0.6	3.9	-0.0	-1.8	0.1	0.2	-0.0	-0.4	-1.2	-0.8	-0.3	0.2	-0.0	-0.1	2.0	-0.7	0.1	0.4	-0.2	-0.7	-1.0	0.8	0.4	0.0
Number of treatments/medications taken	0.2	0.3	3.9	0.1	-0.9	0.1	0.1	0.1	0.0	-1.3	-0.3	-0.4	0.0	0.6	-0.3	0.1	-0.4	-0.2	-2.0	-0.1	-0.4	0.3	0.1	-0.0	0.2
Impedance of leg (right)	0.2	1.1	8.0	0.3	0.7	-0.4	0.4	0.1	-1.0	0.5	0.7	0.0	0.3	-2.8	-0.3	-1.4	0.6	0.1	-2.2	0.7	0.2	1.3	-1.4	-1.3	0.3
Impedance of leg (left)	0.2	1.1	8.9	0.6	1.0	0.1	0.8	0.5	-0.9	1.1	1.0	0.4	0.7	-3.0	-0.5	-1.0	1.1	0.4	-1.4	0.9	0.9	1.3	-0.6	-0.8	0.6
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.4	-0.2	-0.4	0.0	-0.2	-0.2	-0.1	-0.3	-0.9	-0.1	-0.1	0.0	-0.1	0.0	-1.2	-0.1	0.5	-0.1	-0.0	-1.1	-0.3	-0.0	-0.1
Standing height	0.2	2.4	6.3	1.9	1.1	2.0	1.6	1.6	-0.4	1.6	0.3	1.6	1.8	0.2	-1.6	-0.1	-0.9	2.1	-0.3	2.0	2.5	-1.7	1.8	1.2	2.0
Breastfed as a baby	0.2	0.2	1.5	-0.2	0.0	-0.6	-0.2	-0.4	0.5	-0.9	-0.1	-0.6	-0.2	-0.8	0.1	-0.3	-1.2	-0.1	-0.5	0.2	-0.3	-0.3	-0.3	-0.5	-0.2
Tense / ‘highly strung’	0.2	0.4	2.5	-0.3	-1.6	0.2	-0.3	0.1	-0.9	-0.6	-0.5	-0.4	-0.3	0.2	-0.3	1.4	-0.4	-0.1	0.6	-0.3	0.7	-1.0	-0.3	0.6	-0.2
Birth weight of first child	0.2	0.3	1.7	-0.1	0.2	-0.5	-0.4	-0.4	-0.3	-0.2	0.2	-0.1	-0.1	1.3	0.1	-0.1	-0.2	0.1	0.2	0.9	1.1	-1.1	-0.0	-0.5	-0.1
Peak expiratory flow (PEF)	0.2	0.4	3.0	-0.2	0.6	-0.1	-0.3	-0.5	-1.1	-0.3	1.0	-0.2	-0.0	1.0	0.5	-0.9	0.3	-0.2	0.2	0.2	1.7	0.4	-0.8	-0.6	-0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	-0.2	-0.8	0.1	-0.4	-0.3	-0.6	0.6	0.5	0.1	-0.2	0.3	0.9	-0.4	1.0	-0.5	1.0	-0.8	-0.1	0.1	0.4	-0.3	-0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	2.0	0.4	1.4	0.1	0.4	0.2	0.3	0.5	0.5	0.4	0.4	0.6	0.1	0.1	0.2	0.2	1.0	0.6	0.5	-0.0	-0.3	0.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	3.7	-0.5	-0.1	-0.5	-0.6	-0.5	0.1	-0.2	0.3	-0.3	-0.5	0.7	0.7	-0.0	-0.3	-0.2	-0.2	-0.5	-0.6	-1.9	-0.5	-0.6	-0.4
Mood swings	0.2	0.4	2.7	-0.3	-1.6	0.2	-0.1	-0.3	-0.7	-0.3	-0.7	-0.2	-0.1	-1.0	0.5	1.0	-0.7	-0.4	0.5	-0.8	-0.1	-0.7	0.7	0.2	-0.4
Ever had bowel cancer screening	0.2	0.2	0.6	0.4	0.4	0.2	0.4	0.3	-0.1	0.7	-0.0	0.5	0.3	0.8	-0.3	0.7	0.4	0.5	0.1	0.5	0.8	-0.3	0.4	0.4	0.5
Medication: Gliclazide	0.2	0.2	1.5	0.1	-0.1	0.6	0.3	0.3	-0.4	0.7	0.2	0.4	0.1	0.1	-0.1	0.3	1.2	0.1	0.8	-0.5	-0.1	0.2	0.5	0.6	0.1
Illnesses of father: High blood pressure	0.2	0.2	0.7	-0.4	-0.6	-0.1	-0.6	-0.2	-0.8	-0.2	-0.1	-0.2	-0.4	-0.7	0.6	-0.8	-0.7	-0.1	-0.2	-0.6	-0.0	-0.5	-0.3	-0.3	-0.4
Heart disease (siblings)	0.2	0.3	1.4	0.5	1.2	0.3	0.4	0.5	0.9	-0.8	0.1	0.2	0.5	-0.7	-0.6	-0.3	-0.7	0.5	-0.1	0.4	0.3	0.4	-0.0	0.2	0.6
Alzheimer’s Disease (in mother)	0.1	0.2	1.1	-0.3	0.1	-0.3	0.0	-0.5	-0.5	-0.3	-0.2	-0.4	-0.1	0.3	0.1	-0.0	1.0	-0.4	-0.1	-0.2	-0.9	0.5	0.1	-0.4	-0.3
Blood Red Count	0.1	1.4	6.0	-0.4	-0.7	-0.9	-0.5	-0.9	-0.6	-0.8	-1.4	-1.1	-0.4	-1.9	0.8	-2.1	-2.2	-0.9	-2.5	-0.5	-0.2	-0.4	-1.2	-1.6	-0.4
Lung FEV1/FVC ratio	0.1	0.5	3.3	-0.2	0.8	-0.3	-0.2	-0.3	-0.8	-1.2	1.1	-0.3	-0.1	0.1	0.6	-0.2	1.0	-0.3	0.1	0.4	1.8	0.5	-0.8	-0.3	-0.3
Hair Pigment	0.1	1.7	9.0	0.6	0.8	0.1	0.6	0.9	-1.5	0.4	-0.2	1.2	0.5	2.9	-0.5	0.8	3.0	0.5	2.6	0.3	1.1	1.5	-0.4	1.3	0.5
Tanning	0.1	0.7	1.6	0.8	0.1	1.0	1.0	0.7	0.7	0.8	0.5	0.9	1.0	-1.0	-0.1	1.3	0.6	0.4	1.3	0.6	-0.5	0.6	1.1	1.0	0.6
Hearing difficulty/problems: Yes	0.1	0.2	1.6	-0.1	-0.1	-0.3	-0.3	-0.4	-1.0	0.6	1.2	0.1	0.1	-0.2	0.3	-0.9	-0.0	-0.3	0.1	-0.1	-0.5	0.5	0.5	-0.1	-0.1
Systolic blood pressure, automated reading	0.1	0.3	1.3	0.0	0.9	0.1	0.2	0.5	-0.3	-0.5	-0.8	0.1	-0.0	0.3	-0.8	1.2	-0.1	0.1	1.0	-0.4	-1.0	-0.1	0.2	0.8	0.2
Sitting height	0.1	0.8	3.8	0.5	-0.5	0.9	0.5	0.5	-0.1	-0.1	-1.6	0.3	0.4	1.4	0.0	0.4	-0.6	0.5	2.0	-0.0	0.9	-1.5	1.1	1.3	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.8	0.1	-0.7	0.4	0.0	0.1	-0.6	-0.6	-0.7	0.0	0.1	-0.1	-0.3	0.9	0.1	-0.0	0.9	0.2	0.3	0.2	-0.1	0.5	0.1
Medication: Cholesterol lowering	0.1	0.2	1.1	0.2	0.1	0.2	0.3	0.3	-0.2	-0.5	-0.2	-0.0	0.1	-0.7	-0.6	0.3	-1.0	0.4	-1.1	0.4	0.6	-0.3	0.3	0.1	0.3
Medication: Aspirin	0.1	0.2	0.7	0.3	-0.8	0.4	0.2	0.2	-0.7	0.5	-0.7	0.2	0.2	-0.1	-0.0	0.4	-0.3	0.0	0.2	0.3	0.7	0.4	0.1	0.1	0.3
Medication: Aspirin	0.1	0.2	1.2	0.1	-1.0	0.1	-0.0	-0.0	-1.1	0.3	-0.8	0.1	0.2	-0.3	0.2	0.2	-0.2	-0.1	0.3	0.3	0.7	0.3	-0.0	-0.3	0.1
Ever smoked	0.1	0.2	1.3	-0.2	0.6	-0.3	-0.0	-0.2	-0.5	0.2	-0.2	-0.1	-0.1	0.9	-0.6	0.2	-0.1	0.0	-0.8	0.0	-0.4	-1.1	-0.6	-0.7	-0.0
Ever depressed for a whole week	0.1	0.2	0.9	-0.2	-0.4	-0.1	0.1	-0.0	-0.9	0.5	0.4	0.3	0.0	0.2	-0.7	0.9	0.1	0.2	0.2	0.2	-0.4	-0.1	-0.3	-0.3	-0.1

Hub : Genes

AKAP11

Models

Trait associations