Hub : Genes

AKAP11

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1650 0.0340 3.8e-14 0.205 0.124 0.185 0.189 0.195 1.8e-24 8.1e-15 5.6e-22 1.5e-22 3.6e-23
2 GTEx Artery Aorta 0.2560 0.0810 1.9e-04 0.089 NA 0.069 NA 0.114 1.3e-05 NA 1.2e-04 NA 7.7e-07
3 GTEx Artery Tibial 0.1729 0.0435 7.4e-08 0.113 NA 0.137 NA 0.140 3.6e-09 NA 7.2e-11 NA 4.3e-11
4 GTEx Brain Cerebellar Hemisphere 0.2070 0.0830 3.5e-03 0.202 NA 0.111 NA 0.186 6.6e-06 NA 8.8e-04 NA 1.6e-05
5 GTEx Brain Cerebellum 0.3030 0.0850 2.1e-05 0.293 NA 0.296 NA 0.244 2.5e-09 NA 2.1e-09 NA 8.0e-08
6 GTEx Brain Hypothalamus 0.3590 0.1150 3.6e-03 -0.002 NA -0.008 NA -0.004 3.5e-01 NA 5.5e-01 NA 4.1e-01
7 GTEx Colon Sigmoid 0.2100 0.0770 2.2e-03 0.060 NA 0.066 NA 0.091 3.7e-03 NA 2.3e-03 NA 4.0e-04
8 GTEx Esophagus Gastroesophageal Junction 0.1690 0.0710 8.8e-03 -0.008 NA -0.007 NA -0.008 8.4e-01 NA 7.0e-01 NA 8.0e-01
9 GTEx Esophagus Mucosa 0.2460 0.0590 7.6e-09 0.178 NA 0.150 NA 0.170 5.3e-12 NA 3.2e-10 NA 1.6e-11
10 GTEx Esophagus Muscularis 0.2270 0.0590 2.7e-07 0.192 NA 0.177 NA 0.185 8.5e-12 NA 6.0e-11 NA 2.1e-11
11 GTEx Lung 0.0813 0.0388 1.0e-02 -0.002 NA -0.003 NA 0.017 5.5e-01 NA 6.6e-01 NA 1.8e-02
12 GTEx Muscle Skeletal 0.1451 0.0388 2.4e-07 0.103 NA 0.086 NA 0.104 3.0e-10 NA 7.8e-09 NA 2.4e-10
13 GTEx Nerve Tibial 0.1235 0.0424 4.4e-04 -0.004 NA 0.011 NA 0.009 9.3e-01 NA 5.1e-02 NA 7.0e-02
14 GTEx Skin Not Sun Exposed Suprapubic 0.1390 0.0520 1.1e-03 -0.004 NA -0.002 NA -0.003 6.9e-01 NA 4.1e-01 NA 4.8e-01
15 GTEx Skin Sun Exposed Lower leg 0.0570 0.0250 5.4e-03 0.051 NA 0.036 NA 0.037 4.7e-05 NA 5.6e-04 NA 4.6e-04
16 GTEx Testis 0.1500 0.0540 1.2e-03 0.034 NA 0.093 NA -0.004 1.2e-02 NA 6.4e-05 NA 5.6e-01
17 METSIM Adipose 0.0346 0.0161 5.3e-03 0.011 0.005 0.004 0.005 0.006 8.2e-03 5.9e-02 8.3e-02 4.7e-02 3.7e-02
18 TCGA Breast Invasive Carcinoma 0.0540 0.0320 3.7e-04 0.007 0.023 0.026 NA 0.009 9.8e-03 1.2e-05 3.8e-06 NA 4.1e-03
19 TCGA Brain Lower Grade Glioma 0.0336 0.0192 6.9e-03 -0.002 0.016 0.000 NA 0.000 5.7e-01 5.0e-03 3.2e-01 NA 3.2e-01
20 TCGA Lung Squamous Cell Carcinoma 0.0410 0.0187 5.2e-05 0.052 0.044 0.039 NA 0.045 1.5e-06 8.6e-06 3.0e-05 NA 7.1e-06
21 TCGA Ovarian Serous Cystadenocarcinoma 0.0410 0.0240 7.4e-03 0.003 0.018 0.005 NA 0.005 1.9e-01 2.1e-02 1.3e-01 NA 1.4e-01
22 TCGA Thyroid Carcinoma 0.0710 0.0270 1.9e-06 0.087 0.052 0.057 NA 0.079 7.4e-09 8.7e-06 3.0e-06 NA 3.7e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bipolar Disorder (2018) 0.8 1.3 3.0 -1.3 -0.9 -1.4 -1.2 -1.2 -0.9 -0.9 -0.0 -1.1 -1.1 0.6 1.1 -1.3 1.1 -1.4 0.1 -1.4 -1.4 0.2 -1.7 -1.0 -1.4
Bipolar Disorder or Schizophrenia 0.5 1.3 4.0 -1.2 -0.2 -1.3 -1.3 -1.2 -1.1 -0.0 0.5 -0.6 -1.1 -1.5 1.0 -2.0 1.0 -0.9 -0.4 -1.3 -0.6 -0.4 -2.0 -1.8 -1.3
Depressed Affect (Nagel 2018) 0.8 1.7 4.3 1.4 -0.0 1.6 1.3 1.5 -0.4 1.3 1.5 1.7 1.5 -1.0 -1.1 2.1 0.5 1.3 1.2 1.0 0.5 0.7 2.0 1.4 1.4
Depression (Nagel 2018) 1.7 2.6 5.6 2.3 1.0 1.8 2.2 2.1 -0.7 -0.5 0.1 1.8 2.4 0.2 -1.8 1.5 -0.5 2.3 0.4 1.8 1.9 1.0 1.3 1.7 2.3
Intelligence (Savage-Jansen 2018) 0.3 0.8 6.6 0.3 0.1 0.8 0.3 -0.1 -1.2 -0.6 -0.6 -0.2 0.4 -1.9 -0.1 -1.6 -2.6 0.0 -0.5 -0.1 -0.3 -1.2 0.9 -0.1 0.3
Neuroticism (Nagel 2018) 0.3 0.8 3.3 0.7 -1.2 0.8 0.6 0.7 -1.5 -0.1 0.3 0.8 0.9 -1.0 -0.4 1.8 -0.3 0.8 0.9 0.3 -0.5 -0.2 1.4 0.8 0.7
Schizophrenia (2018) 0.4 0.7 5.7 -0.5 0.5 -0.6 -0.7 -0.6 -0.6 0.7 0.6 0.1 -0.5 -2.4 0.3 -1.5 0.3 -0.0 -0.7 -0.5 0.3 -0.8 -1.1 -1.5 -0.5
Schizophrenia vs Biploar Disorder 2.6 3.5 6.8 2.5 1.3 2.6 2.3 2.4 -0.2 1.3 0.4 2.2 2.3 -1.2 -2.1 0.8 -0.0 2.4 0.2 2.0 1.7 1.1 2.6 2.2 2.5
Worry (Nagel 2018) 0.2 0.5 2.6 0.0 -1.5 -0.5 0.0 0.1 -1.1 -1.6 -1.0 -0.1 0.1 -0.1 0.2 1.5 -0.4 0.3 0.6 0.2 -0.8 -0.5 -0.0 -0.0 0.0
Alzheimer’s Disease (in mother) 0.1 0.2 1.1 -0.3 0.1 -0.3 0.0 -0.5 -0.5 -0.3 -0.2 -0.4 -0.1 0.3 0.1 -0.0 1.0 -0.4 -0.1 -0.2 -0.9 0.5 0.1 -0.4 -0.3
Alzheimer’s Disease (in father) 2.8 3.1 5.9 2.2 2.1 1.6 2.0 1.9 2.4 0.3 1.7 1.7 2.2 1.2 -2.0 1.4 0.6 2.1 -1.1 2.2 0.6 1.8 1.9 1.0 2.1
Alzheimer’s Disease (including proxy) 0.6 0.8 1.7 1.0 1.1 0.6 1.0 0.7 0.8 0.1 0.9 0.7 1.1 0.7 -1.1 0.8 1.3 0.9 -0.7 1.3 -0.4 1.1 0.8 0.2 1.0
Crohns Disease (2017) 3.3 7.3 24.6 2.2 1.2 2.4 1.9 1.8 1.8 4.3 5.0 3.2 2.2 1.1 -1.5 1.8 4.8 1.3 3.8 1.7 1.3 3.8 2.0 2.3 1.9
Irritable Bowel Disease (IBD) 0.9 2.0 13.0 0.5 -0.7 0.6 0.2 0.0 0.6 2.4 3.0 1.3 0.5 -0.1 0.1 1.0 3.6 -0.3 2.3 0.4 -0.5 2.6 0.5 0.4 0.2
Ulcerative Colitis (UC) 0.9 1.7 4.7 -1.5 -2.2 -1.6 -1.6 -1.7 -0.7 -0.5 -0.2 -1.1 -1.5 -0.5 1.6 -0.1 1.1 -1.8 0.1 -1.0 -2.0 0.3 -1.5 -1.6 -1.6
Major Depression (MDD) 0.5 0.6 2.4 -0.1 -1.0 -0.8 -0.2 -0.1 -0.3 -1.5 -1.3 -0.6 -0.1 0.6 0.6 -0.5 -0.4 0.0 -0.9 -0.6 -1.3 -0.9 -1.0 -0.4 -0.1
Reaction Time 0.8 1.5 10.4 1.0 1.9 1.2 1.1 1.1 0.1 1.1 0.4 0.7 1.1 -3.2 -1.3 -0.0 -0.9 1.4 -1.0 1.1 -0.4 -0.5 1.3 0.2 1.1
Verbal and Numeric Reasoning (VNR) 0.7 1.8 3.8 1.8 1.3 1.6 1.7 1.3 0.3 0.5 1.9 1.5 1.9 -0.5 -1.4 -0.7 -0.1 1.6 -1.6 1.7 1.3 0.8 1.0 0.3 1.8
Breast Cancer 0.3 0.8 6.3 -0.8 -0.3 -0.3 -0.9 -0.7 0.5 -2.5 0.0 -1.4 -0.8 -0.8 0.3 -0.2 -1.0 -0.4 -1.4 -0.5 0.1 -1.0 -0.3 -0.5 -0.7
Ovarian Cancer 0.5 0.6 2.2 -0.5 -0.9 -0.6 -0.6 -0.6 -0.4 -1.5 -1.5 -0.8 -0.6 -1.0 0.6 0.5 -0.4 -0.8 0.3 -0.6 -0.4 -1.2 -1.2 -0.3 -0.4
Prostate Cancer 0.3 0.4 3.8 -0.0 0.3 -0.3 -0.1 -0.3 1.1 0.6 0.7 0.0 -0.0 1.9 0.6 -0.9 -0.2 -0.3 0.1 0.2 0.3 1.0 -0.1 -0.6 -0.2
Age at First Birth 3.5 5.1 16.0 -2.3 -2.5 -1.3 -2.3 -2.1 0.7 -2.3 -3.0 -2.8 -2.4 -1.1 1.7 -1.6 -4.0 -2.0 -0.7 -2.9 -2.6 -3.3 -0.8 -1.3 -2.1
Bipolar Disorder (2011) 2.1 2.0 4.6 -1.6 -0.3 -1.7 -1.3 -1.9 0.7 -1.4 -1.1 -1.6 -1.5 0.7 1.4 -1.3 -1.0 -1.7 -0.9 -1.3 -1.9 -1.3 -1.7 -2.2 -1.5
Body Mass Index (BMI) (2010) 0.6 0.8 2.1 1.2 0.7 0.9 1.2 0.8 -0.8 0.2 0.2 1.0 1.1 -1.2 -1.1 1.4 0.2 0.9 -0.7 1.3 0.1 0.3 0.4 -0.1 1.2
Coronary Artery Disease (CAD) 0.2 0.3 0.8 0.4 0.1 0.8 0.3 0.5 0.7 0.3 0.2 0.8 0.1 -0.9 -0.2 0.3 0.5 0.5 0.9 -0.2 0.0 0.0 0.8 0.7 0.3
Crohns Disease (2012) 3.9 6.2 15.4 2.2 1.8 2.8 2.1 2.0 1.3 3.7 3.9 2.9 2.2 -0.1 -1.4 1.9 3.7 1.7 3.5 1.5 1.9 2.9 2.8 2.9 1.9
Mean Putamen Volume 0.4 0.5 4.4 -0.2 -0.4 0.1 -0.2 -0.3 -0.2 1.0 1.3 0.1 0.1 -1.0 -0.0 1.0 -2.1 -0.2 0.2 0.4 -0.9 -0.5 0.6 -0.1 -0.1
Fasting Glucose 0.3 0.3 1.6 -0.8 -0.7 -0.3 -0.7 -0.4 0.1 -0.3 -0.2 -0.4 -0.7 -1.0 0.5 0.2 -0.6 -0.3 0.8 -0.4 -0.2 -1.2 0.2 0.0 -0.7
HbA1C 0.2 0.2 1.2 0.3 -0.1 0.1 0.1 -0.2 0.5 -0.6 -1.0 -0.2 -0.0 0.9 0.0 0.2 -0.2 -0.4 0.3 0.3 -1.1 -0.0 0.1 0.4 0.2
HDL Cholesterol 4.9 8.2 13.8 -3.6 -3.1 -3.6 -3.4 -3.5 -1.2 -1.5 -2.4 -3.4 -3.4 -0.2 3.7 -2.7 -0.9 -3.5 -0.7 -3.2 -1.5 -2.2 -3.4 -3.2 -3.7
LDL Cholesterol 1.2 1.9 5.3 -1.7 -2.3 -1.6 -1.6 -1.7 -0.2 -0.7 -1.3 -1.6 -1.4 -0.5 1.8 -0.0 0.1 -2.0 -0.0 -1.5 -1.3 -0.7 -1.4 -1.6 -1.7
Lupus 1.1 1.6 3.8 1.2 0.2 1.7 1.1 1.2 -0.9 1.9 1.5 1.8 1.3 0.2 -1.1 -0.2 1.3 0.8 1.7 1.4 0.7 1.4 1.6 1.6 1.1
Neuroticism (2016) 0.8 1.2 5.2 -0.7 -2.3 -1.0 -0.7 -1.2 -2.0 -1.4 -1.5 -1.0 -0.5 0.5 1.5 0.6 -0.6 -1.3 -0.3 -0.4 -1.0 -0.4 -0.6 -1.0 -0.9
Primary Biliary Cirrhosis 1.3 1.8 11.4 -0.4 -0.4 -0.9 -0.5 -0.8 -1.2 -3.2 -1.4 -1.5 -0.4 0.5 0.9 -0.6 -1.5 -0.5 -3.4 0.2 -0.1 -0.5 -1.5 -1.9 -0.4
Rheumatoid Arthritis 1.5 2.0 10.0 1.0 0.3 1.4 0.8 1.2 0.2 3.2 2.2 2.2 1.1 -0.6 -1.1 0.9 1.8 1.0 1.4 0.7 1.5 1.7 1.1 1.3 0.9
Schizophrenia (2014) 0.4 0.8 5.9 -0.6 0.1 -0.5 -0.7 -0.6 -1.2 1.0 0.7 0.1 -0.6 -2.4 0.3 -1.7 0.4 -0.3 -0.3 -0.5 0.4 -0.3 -1.1 -1.1 -0.6
Triglycerides 0.4 0.6 3.4 0.8 0.6 0.7 0.8 0.6 -0.1 -0.0 0.8 0.7 0.6 -0.3 -1.2 1.8 1.1 0.9 -0.1 1.0 -0.5 0.3 0.8 0.6 0.8
Type 2 Diabetes (T2D) (2012) 0.3 0.3 3.3 0.0 0.3 -0.5 -0.1 0.0 1.1 -0.1 0.2 0.2 -0.4 0.4 -0.0 0.7 0.2 -0.2 0.4 -0.4 -1.8 0.9 -0.5 -0.2 -0.1
Ulcerative Colitis 0.8 1.2 2.2 -1.2 -1.2 -1.5 -1.2 -1.4 -0.3 -1.4 -0.2 -1.3 -1.2 -0.8 1.3 -0.5 0.9 -1.3 -0.3 -0.8 -1.0 0.2 -1.1 -1.5 -1.4
Blood Eosinophil Count 1.9 14.3 30.7 5.0 4.6 4.0 5.0 4.5 1.9 -4.2 -1.9 2.0 4.7 -0.1 -4.8 2.3 -1.9 4.8 -5.5 4.7 3.1 -0.1 2.7 1.8 5.3
Blood Platelet Count 0.9 10.3 17.4 4.0 2.1 4.0 3.9 3.9 -0.1 3.2 2.7 3.8 4.1 -0.2 -3.8 2.6 1.5 3.8 1.0 3.3 2.3 2.5 4.2 3.9 4.0
Blood Red Count 0.1 1.4 6.0 -0.4 -0.7 -0.9 -0.5 -0.9 -0.6 -0.8 -1.4 -1.1 -0.4 -1.9 0.8 -2.1 -2.2 -0.9 -2.5 -0.5 -0.2 -0.4 -1.2 -1.6 -0.4
Blood White Count 1.4 10.6 21.6 -4.4 -4.5 -3.4 -4.4 -3.8 -0.2 -0.6 -2.3 -3.4 -4.4 -0.1 4.2 -1.8 0.0 -4.6 3.5 -4.6 -2.4 -1.2 -2.3 -1.7 -4.6
Heel T-Score 8.4 66.6 139.2 7.7 6.5 8.5 8.5 8.9 -0.1 5.8 5.6 9.5 7.9 9.0 -7.6 9.3 7.2 7.8 11.6 7.2 5.2 8.5 10.1 11.8 7.6
BMI 1.3 7.5 14.5 3.6 2.0 2.6 3.7 3.4 0.4 1.9 1.6 3.5 3.8 1.1 -3.3 3.5 0.2 3.5 -0.6 3.8 1.5 0.9 2.8 2.5 3.7
Height 0.2 3.0 11.2 2.0 0.6 2.0 1.9 1.7 -0.5 1.3 0.2 1.8 2.0 0.8 -1.8 0.3 -0.2 2.3 -0.5 2.7 3.3 -2.3 1.9 1.3 2.1
Waist Hip Ratio (WHR) 0.2 0.8 5.8 0.2 -0.3 0.9 -0.2 0.2 0.8 2.4 1.4 0.7 0.2 0.1 -0.2 0.6 0.9 -0.2 1.6 -0.5 0.0 1.5 0.4 0.9 0.1
Systolic Blood Pressure 0.2 0.9 6.5 -0.8 0.3 -0.0 -0.5 -0.1 -1.3 0.0 -1.4 -0.3 -0.9 -0.7 -0.1 0.3 0.7 -0.8 2.6 -1.7 -0.9 0.0 -0.2 0.6 -0.8
Smoking Status 0.3 0.7 2.1 0.7 1.2 0.5 0.6 0.7 -1.0 1.0 0.8 0.7 0.7 1.5 -1.0 1.1 0.9 0.7 0.6 0.9 0.8 -0.3 0.3 1.0 0.8
Allergy or Eczema 2.8 7.4 19.8 2.6 1.9 3.1 2.4 2.2 0.3 4.5 4.1 3.3 2.6 0.8 -1.8 2.3 3.1 1.8 2.7 2.5 1.4 2.8 3.9 3.3 2.4
Cardiovascular Disease 0.2 0.8 4.6 -0.5 -2.1 0.2 -0.6 -0.0 -1.7 -0.1 -1.0 -0.0 -0.5 -0.5 -0.3 0.8 0.7 -0.4 1.5 -1.3 -0.5 0.6 0.5 0.9 -0.5
Hypothyroidism (self reported) 2.1 4.8 25.7 1.0 1.3 0.0 1.2 0.7 1.3 -5.0 -3.6 -1.2 0.9 -0.3 -0.9 -0.5 -4.8 1.2 -5.1 0.5 -1.0 -2.1 0.1 -0.9 1.3
Respiratory disease 1.2 2.6 9.4 1.9 0.3 2.0 1.8 1.7 -0.5 1.9 1.0 1.7 1.7 0.3 -1.9 1.5 0.9 1.7 -0.3 2.0 0.6 0.7 3.1 2.0 2.0
Type 2 Diabetes (T2D) (2018) 0.2 0.3 0.8 0.6 -0.2 0.7 0.5 0.7 0.6 0.2 -0.7 0.7 0.5 -0.1 -0.7 0.0 0.5 0.6 0.9 0.1 0.5 0.5 0.6 0.9 0.7
Lung FEV1/FVC ratio 0.1 0.5 3.3 -0.2 0.8 -0.3 -0.2 -0.3 -0.8 -1.2 1.1 -0.3 -0.1 0.1 0.6 -0.2 1.0 -0.3 0.1 0.4 1.8 0.5 -0.8 -0.3 -0.3
Lung FVC 0.9 4.5 11.9 -2.4 -0.8 -2.6 -2.6 -2.6 -1.3 -1.0 -0.4 -2.2 -2.2 -0.5 2.5 -3.4 -1.5 -2.2 -2.2 -2.0 -1.1 -0.6 -2.7 -3.2 -2.4
Neuroticism 0.2 0.6 3.9 -0.0 -1.8 0.1 0.2 -0.0 -0.4 -1.2 -0.8 -0.3 0.2 -0.0 -0.1 2.0 -0.7 0.1 0.4 -0.2 -0.7 -1.0 0.8 0.4 0.0
Chronotype (morning person) 1.2 2.8 5.4 -2.1 -2.1 -1.9 -1.9 -1.8 -0.7 -1.0 -1.9 -1.6 -2.2 0.9 2.3 0.2 -0.6 -2.0 0.9 -2.0 -1.3 -2.1 -2.1 -1.1 -2.1
Hair Pigment 0.1 1.7 9.0 0.6 0.8 0.1 0.6 0.9 -1.5 0.4 -0.2 1.2 0.5 2.9 -0.5 0.8 3.0 0.5 2.6 0.3 1.1 1.5 -0.4 1.3 0.5
Tanning 0.1 0.7 1.6 0.8 0.1 1.0 1.0 0.7 0.7 0.8 0.5 0.9 1.0 -1.0 -0.1 1.3 0.6 0.4 1.3 0.6 -0.5 0.6 1.1 1.0 0.6
Hand grip strength (left) 0.4 1.1 2.2 1.3 1.5 0.7 1.1 1.0 1.4 0.6 0.5 1.1 1.3 1.3 -0.8 0.9 -1.0 1.3 -0.7 1.4 0.9 -1.1 0.2 0.4 1.4
Number of treatments/medications taken 0.2 0.3 3.9 0.1 -0.9 0.1 0.1 0.1 0.0 -1.3 -0.3 -0.4 0.0 0.6 -0.3 0.1 -0.4 -0.2 -2.0 -0.1 -0.4 0.3 0.1 -0.0 0.2
Average weekly spirits intake 0.4 0.5 1.5 -1.0 -0.4 -0.6 -1.0 -0.5 0.4 -1.0 0.1 -0.7 -1.0 1.2 0.6 0.4 0.6 -0.5 0.8 -0.4 1.2 -0.3 -0.2 0.2 -1.0
Sensitivity / hurt feelings 1.5 2.6 9.2 -1.6 -3.0 -1.2 -1.5 -1.7 -1.2 -1.6 -1.5 -1.8 -1.4 -1.0 1.5 -0.8 -2.0 -1.4 -0.9 -2.0 -1.7 -2.2 -0.3 -1.2 -1.6
Frequency of depressed mood in last 2 weeks 0.5 0.8 1.7 1.1 -0.4 1.1 1.0 0.9 -0.0 -1.0 -0.5 0.6 1.2 0.7 -0.7 1.0 -0.7 1.0 0.4 1.0 1.3 0.1 0.9 0.9 1.1
Hearing difficulty/problems: Yes 0.1 0.2 1.6 -0.1 -0.1 -0.3 -0.3 -0.4 -1.0 0.6 1.2 0.1 0.1 -0.2 0.3 -0.9 -0.0 -0.3 0.1 -0.1 -0.5 0.5 0.5 -0.1 -0.1
Relative age of first facial hair 1.9 3.8 7.4 -2.6 -1.9 -2.7 -2.6 -2.4 -0.3 -0.7 -1.0 -1.9 -2.4 -0.4 2.4 -0.7 0.1 -2.6 1.9 -2.4 -1.9 -0.2 -2.6 -1.8 -2.7
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 4.2 -0.0 -0.4 -0.6 0.1 -0.4 0.5 -2.0 -0.6 -0.8 0.1 0.3 0.2 -0.2 -0.5 -0.4 -1.6 0.6 0.2 1.6 -1.1 -1.2 -0.1
Ever used hormone-replacement therapy (HRT) 1.3 1.7 3.3 1.7 0.7 1.5 1.8 1.3 0.7 -0.9 0.5 0.9 1.7 -0.6 -1.7 1.2 -0.7 1.1 -1.4 1.6 1.1 1.8 1.1 1.1 1.7
Ever had hysterectomy (womb removed) 1.4 1.5 3.3 1.7 0.6 1.4 1.8 1.7 0.3 -0.3 0.2 1.1 1.7 -0.3 -1.5 1.2 -1.0 1.7 -1.0 1.2 1.7 0.2 0.8 1.0 1.8
Systolic blood pressure, automated reading 0.1 0.3 1.3 0.0 0.9 0.1 0.2 0.5 -0.3 -0.5 -0.8 0.1 -0.0 0.3 -0.8 1.2 -0.1 0.1 1.0 -0.4 -1.0 -0.1 0.2 0.8 0.2
Eye problems/disorders: Diabetes related eye disease 0.6 0.6 2.4 0.9 0.8 1.2 0.6 0.9 0.1 0.8 0.6 0.9 0.8 -0.6 -0.8 -0.5 -0.4 0.7 0.9 0.8 1.6 0.3 0.5 1.0 0.9
Angina 0.3 0.4 2.3 0.2 -1.1 0.1 0.1 0.2 -1.5 0.2 -0.4 0.2 0.2 -1.3 -0.2 -0.6 -1.3 0.5 -0.7 -0.2 0.3 -0.1 0.6 -0.4 0.3
Medication for hormone replacement therapy 0.6 0.7 1.9 1.1 -0.2 1.0 0.9 0.6 -0.1 -1.4 -0.9 0.0 1.1 -1.1 -0.7 0.2 -0.9 0.5 -1.2 1.0 0.4 0.9 0.7 0.4 1.1
Vitamin and mineral supplements 0.6 0.8 4.4 -0.8 -2.0 -0.5 -1.0 -0.6 0.0 -0.4 -0.4 -0.4 -0.8 -0.8 1.1 -0.3 1.0 -0.9 2.1 -1.2 -0.6 0.5 -0.3 0.1 -0.9
Supplements: Zinc 0.7 0.8 2.7 1.0 1.7 1.2 1.1 0.5 -0.1 -0.9 0.5 0.1 0.9 -0.7 -1.0 -0.5 -0.6 0.8 -1.6 0.7 0.1 -0.0 1.4 0.2 1.0
Medication: Co-codamol 1.1 1.2 3.2 0.7 0.5 0.6 0.8 1.0 -1.2 1.4 1.6 1.3 1.0 0.0 -1.0 1.8 0.7 1.0 1.6 1.4 1.5 0.5 0.9 1.1 0.8
Medication: Metformin 0.4 0.6 3.2 0.5 -0.2 1.2 0.4 0.5 0.5 0.0 -1.2 0.4 0.4 0.3 -0.4 0.5 0.0 0.2 1.8 -0.0 1.3 0.6 1.2 1.0 0.5
Diabetes (father) 0.4 0.5 2.7 -0.6 -0.9 -0.5 -0.7 -0.5 -1.0 0.4 -0.6 -0.2 -0.7 -0.6 1.0 -1.6 0.1 -0.5 -0.9 -0.2 0.2 0.3 -0.5 -0.8 -0.8
Diabetes (mother) 0.3 0.3 2.1 -0.0 -0.4 -0.4 -0.2 -0.2 -1.5 -0.0 -0.4 0.0 -0.1 -0.8 0.5 -0.3 1.2 -0.4 1.1 -0.0 0.5 0.0 -0.7 -0.2 -0.1
Severe depression (siblings) 0.3 0.4 2.6 -0.2 0.1 -0.7 0.0 -0.5 1.6 0.1 0.6 -0.2 0.0 -0.3 0.4 -0.7 -0.0 -0.6 -0.1 -0.2 -1.1 0.6 -0.8 -0.9 -0.3
Pack years adult smoking proportion 0.5 0.8 2.1 1.0 -0.5 0.9 1.0 1.0 -1.0 0.9 -0.1 1.1 0.9 -0.4 -0.5 0.6 1.1 0.8 1.3 1.0 1.5 0.5 0.9 1.3 0.9
Impedance of leg (right) 0.2 1.1 8.0 0.3 0.7 -0.4 0.4 0.1 -1.0 0.5 0.7 0.0 0.3 -2.8 -0.3 -1.4 0.6 0.1 -2.2 0.7 0.2 1.3 -1.4 -1.3 0.3
Leg fat-free mass (left) 0.8 4.3 7.5 2.6 1.3 2.6 2.4 2.5 0.3 1.7 0.9 2.7 2.6 1.7 -2.3 2.2 -0.4 2.7 0.6 2.3 1.5 -0.5 2.7 2.6 2.6
Trunk fat percentage 2.8 11.1 19.1 3.9 3.2 3.5 3.9 4.2 -0.6 3.3 2.8 4.4 4.1 -0.5 -4.0 3.6 1.8 4.0 0.6 4.0 2.7 2.5 3.3 3.5 4.0
Hand grip strength (right) 0.7 1.8 3.9 1.9 1.3 1.1 1.7 1.4 1.6 1.0 0.9 1.5 1.9 0.2 -1.1 0.6 -1.4 1.8 -0.7 1.7 1.4 -1.2 0.8 0.7 2.0
Townsend deprivation index at recruitment 0.4 0.6 2.9 0.1 -0.3 0.3 0.3 0.3 -0.6 1.5 1.5 0.6 0.3 -0.1 -0.5 1.4 1.1 -0.3 1.7 0.0 -0.4 1.0 0.3 0.8 0.0
Current tobacco smoking 0.9 1.5 6.2 1.1 1.6 0.9 0.9 1.2 -0.5 1.6 0.9 1.4 1.1 -0.1 -1.1 0.6 1.7 1.0 1.7 1.2 2.5 1.2 0.4 1.2 1.1
Average weekly fortified wine intake 0.4 0.5 4.3 0.0 0.4 -0.0 0.1 -0.1 2.1 -0.8 0.3 -0.1 0.2 1.4 0.0 -0.9 0.2 0.1 -1.2 0.2 0.5 0.7 0.1 -0.3 0.0
Maternal smoking around birth 1.3 1.8 5.0 1.7 0.6 0.9 1.5 1.7 -0.4 1.3 0.4 1.9 1.6 0.6 -1.8 0.7 2.0 2.1 0.3 2.2 0.9 0.7 0.7 0.8 1.8
Fed-up feelings 0.4 0.7 2.8 0.8 -0.8 0.7 0.9 0.6 0.2 0.7 1.4 1.0 1.0 -1.0 -0.3 1.7 0.4 0.5 0.5 0.5 0.2 1.0 1.0 0.4 0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.4 3.8 1.4 0.4 1.3 1.3 1.3 -0.8 -0.2 0.2 1.2 1.4 -0.1 -1.1 2.0 0.2 1.3 1.7 1.1 1.9 0.1 0.8 1.5 1.4
Relative age voice broke 2.0 3.0 8.9 -2.3 -2.4 -1.8 -2.5 -1.9 -1.1 -0.5 -0.4 -1.4 -2.1 -0.3 2.1 0.6 1.2 -2.1 3.0 -2.1 -0.7 -0.1 -1.6 -0.7 -2.4
Taking other prescription medications 0.5 0.8 5.8 -0.2 -1.5 -0.1 -0.1 -0.3 0.6 -1.7 -0.9 -0.9 -0.2 0.2 0.0 -1.8 -0.4 -0.2 -2.4 -0.3 0.0 -0.0 -0.2 -0.6 -0.2
Age when periods started (menarche) 0.9 2.1 5.5 1.2 2.2 1.6 1.0 1.6 -0.6 1.3 1.9 1.6 1.2 -0.7 -1.4 0.8 2.2 1.6 0.2 1.2 2.3 1.0 1.4 1.8 1.2
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 3.2 1.7 1.6 1.1 1.8 1.4 0.3 -0.1 0.8 1.0 1.6 -0.3 -1.5 1.3 -0.5 1.2 -1.3 1.4 0.9 1.1 0.2 0.7 1.7
Heel bone mineral density (BMD) T-score, automated (left) 2.9 6.6 26.5 1.8 1.3 2.4 2.5 2.3 1.0 2.3 2.3 2.7 2.1 2.8 -2.0 2.8 2.7 1.8 5.1 1.3 -0.4 2.4 4.0 4.1 1.8
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 2.4 -0.8 -0.2 -0.2 -0.9 -0.8 1.6 0.1 -0.4 -0.7 -0.7 -1.0 0.6 -0.7 -1.3 -0.5 -0.4 -0.6 0.2 -0.4 -0.5 -1.2 -0.8
Qualifications: CSEs or equivalent 2.2 2.9 12.1 1.4 0.2 1.6 1.2 1.6 0.5 1.4 1.7 1.8 1.5 -1.0 -0.8 1.9 2.5 0.8 3.5 1.5 1.5 2.5 1.6 2.3 1.3
Serious illness, injury or assault to yourself 1.1 1.3 4.6 1.6 0.3 1.2 1.3 1.1 0.5 -0.8 0.2 0.5 1.5 -0.5 -1.2 -0.1 0.5 1.0 -2.1 1.8 0.2 2.0 0.9 0.1 1.5
High blood pressure 0.3 1.0 3.2 0.7 -1.2 1.4 0.5 1.1 -1.1 -0.9 -1.1 0.6 0.6 -0.4 -1.2 0.9 0.5 0.8 0.9 -0.3 0.1 1.0 1.7 1.8 0.7
Hayfever, allergic rhinitis or eczema 2.0 4.4 13.1 2.1 1.1 2.7 2.0 1.8 0.1 3.0 2.7 2.6 2.2 0.9 -1.6 2.0 2.1 1.7 1.7 1.7 0.7 1.8 3.6 2.9 1.9
Multivitamins +/- minerals 0.9 1.2 5.5 1.2 2.3 0.7 1.2 0.9 -0.2 0.8 0.3 0.9 1.2 1.6 -1.2 0.7 -0.5 1.2 -1.1 1.5 0.9 -0.0 0.4 0.4 1.3
Stomach or abdominal pain in last month 0.4 0.5 4.0 -0.4 -1.3 0.1 -0.4 -0.3 0.4 0.1 -0.6 -0.2 -0.4 -0.6 0.7 0.5 -0.4 -0.6 2.0 -0.7 -0.4 -0.6 0.1 0.4 -0.5
Supplements: Glucosamine 0.7 0.9 5.0 0.1 0.9 1.0 0.2 0.3 1.2 -0.1 1.1 0.2 0.1 2.2 -0.5 1.4 -0.7 0.1 1.2 -0.0 0.8 0.9 1.5 1.6 0.1
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 3.5 -0.9 -1.1 -1.0 -0.9 -1.0 1.3 -1.1 -0.7 -1.2 -1.0 -0.9 1.1 -0.9 -1.7 -1.0 -0.9 -1.3 -1.1 -1.9 -0.6 -1.3 -0.8
Medication: Atenolol 1.6 2.0 4.7 1.2 0.5 1.5 1.3 1.6 0.2 1.5 0.9 1.6 1.2 -0.7 -1.6 0.8 2.2 1.5 1.8 1.2 2.0 1.6 1.4 1.6 1.3
Medication: Levothyroxine sodium 1.4 2.3 18.8 0.4 0.7 -0.4 0.5 0.1 0.4 -3.5 -2.1 -1.0 0.4 0.1 -0.5 -0.9 -2.8 0.4 -4.3 0.1 -1.4 -0.2 -0.3 -1.5 0.5
Sitting height 0.1 0.8 3.8 0.5 -0.5 0.9 0.5 0.5 -0.1 -0.1 -1.6 0.3 0.4 1.4 0.0 0.4 -0.6 0.5 2.0 -0.0 0.9 -1.5 1.1 1.3 0.5
Chronic bronchitis/emphysema (father) 1.8 2.1 4.2 2.0 0.7 1.7 2.0 1.8 0.6 1.4 0.3 1.8 2.0 -0.3 -1.5 0.6 -0.7 1.8 -0.3 1.9 1.5 0.9 1.5 1.4 2.0
High blood pressure (mother) 0.3 0.5 1.8 -0.8 -0.9 -0.6 -0.7 -0.5 1.0 -0.5 -0.6 -0.5 -0.7 0.5 0.4 -0.5 -1.3 -0.4 0.2 -0.9 -0.4 -0.9 -0.4 -0.1 -0.8
Body mass index (BMI) 1.6 6.6 13.4 3.2 2.1 2.6 3.1 3.3 0.4 1.7 1.8 3.3 3.3 1.0 -3.1 3.7 0.8 3.2 0.6 3.1 1.7 1.3 2.6 3.0 3.2
Impedance of leg (left) 0.2 1.1 8.9 0.6 1.0 0.1 0.8 0.5 -0.9 1.1 1.0 0.4 0.7 -3.0 -0.5 -1.0 1.1 0.4 -1.4 0.9 0.9 1.3 -0.6 -0.8 0.6
Leg predicted mass (left) 0.8 4.4 7.7 2.6 1.2 2.6 2.4 2.6 0.4 1.7 0.9 2.7 2.7 1.8 -2.4 2.2 -0.5 2.8 0.7 2.3 1.5 -0.5 2.7 2.6 2.7
Trunk fat mass 2.7 11.7 20.0 4.2 3.1 3.8 4.1 4.3 -0.2 3.2 2.6 4.5 4.3 0.0 -4.1 3.6 1.3 4.2 0.6 4.2 2.8 1.9 3.6 3.7 4.2
Waist circumference 1.3 4.9 8.9 2.6 1.7 2.4 2.5 2.6 0.7 2.4 1.9 2.9 2.6 0.9 -2.6 3.0 1.4 2.4 1.1 2.2 1.5 1.3 2.3 2.7 2.6
Number of incorrect matches in round 1.9 3.1 6.6 -1.9 -0.9 -2.3 -2.0 -1.9 -1.2 -0.1 -1.1 -1.7 -2.0 -0.8 1.9 -2.5 -1.3 -1.9 -1.3 -1.8 -1.8 -1.2 -2.2 -2.6 -2.0
Past tobacco smoking 0.3 0.5 2.8 0.4 0.0 0.5 0.2 0.4 0.7 0.2 0.5 0.5 0.3 -1.3 0.4 -0.6 0.5 0.3 0.5 0.3 1.6 1.7 0.6 0.4 0.2
Alcohol usually taken with meals 7.4 12.0 21.3 -3.7 -2.8 -3.3 -3.9 -3.9 -1.4 -3.8 -4.3 -4.6 -3.8 -0.3 3.7 -4.0 -4.5 -3.8 -1.9 -3.9 -2.7 -2.8 -2.6 -3.3 -3.7
Nervous feelings 0.7 1.2 3.6 -1.3 -1.9 -1.8 -1.1 -1.1 -0.1 -1.2 -0.8 -1.1 -1.1 0.1 1.0 0.2 0.1 -0.9 0.5 -0.9 -1.8 -0.6 -1.5 -1.3 -1.3
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.4 3.1 1.4 -0.3 1.4 1.2 1.3 -1.5 -0.2 -0.4 1.3 1.5 0.1 -1.1 1.7 0.2 1.2 1.7 0.8 1.0 0.6 1.1 1.7 1.4
Hearing difficulty/problems with background noise 0.3 0.4 4.5 0.3 -0.3 -0.1 0.4 0.1 -0.5 0.7 0.6 0.5 0.4 2.1 -0.3 0.4 0.5 -0.2 1.0 0.2 -0.3 0.8 0.6 0.8 0.2
Hair/balding pattern: Pattern 2 0.3 0.3 1.9 0.2 -0.2 -0.8 0.5 0.0 1.1 0.3 0.5 0.1 0.3 0.1 -0.1 0.3 1.4 -0.1 -0.2 0.7 -0.5 1.2 -0.6 -0.5 0.2
Had menopause 4.0 5.0 8.6 2.7 2.4 2.3 2.9 2.9 -0.5 1.3 0.7 2.5 2.9 0.3 -2.9 1.6 0.4 2.8 -0.2 2.9 1.9 1.7 2.7 2.5 2.8
Had other major operations 1.4 1.7 6.4 0.8 1.7 1.1 0.9 0.8 0.0 2.5 1.9 1.4 0.8 0.8 -1.0 1.5 1.5 0.7 1.3 1.3 1.4 1.6 1.5 1.2 0.8
Forced vital capacity (FVC) 0.9 3.4 11.3 -1.7 -0.7 -2.0 -2.0 -2.3 -0.3 -0.6 -0.3 -1.7 -1.7 1.0 2.1 -3.4 -1.8 -1.5 -2.2 -1.4 -0.7 -2.0 -2.2 -3.1 -1.8
Heel bone mineral density (BMD) T-score, automated (right) 4.2 9.5 21.7 2.8 2.1 3.0 3.3 3.1 1.8 2.6 3.1 3.5 3.0 3.5 -2.8 3.4 2.7 2.5 4.7 2.4 0.1 3.5 3.9 4.5 2.7
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 1.4 -0.2 -0.4 0.0 -0.2 -0.2 -0.1 -0.3 -0.9 -0.1 -0.1 0.0 -0.1 0.0 -1.2 -0.1 0.5 -0.1 -0.0 -1.1 -0.3 -0.0 -0.1
Qualifications: None of the above 0.5 1.1 6.2 0.1 -0.4 -0.5 0.4 0.6 -1.7 2.5 1.6 1.2 0.2 0.0 -0.6 1.7 1.8 0.4 0.6 0.7 -1.2 0.7 0.3 0.4 0.1
Financial difficulties in last 2 years 0.5 0.7 5.7 -0.2 -0.7 -0.8 -0.3 -0.7 -0.3 0.0 -0.3 -0.2 -0.1 -2.4 1.3 -1.2 -0.7 -0.7 0.0 0.1 0.4 -0.5 -1.0 -1.6 -0.3
Mouth/teeth dental problems 4.4 6.7 12.2 -2.6 -2.2 -2.7 -2.7 -2.8 0.9 -3.5 -2.3 -3.5 -2.7 -1.3 2.6 -3.1 -2.8 -2.5 -2.0 -2.5 -1.4 -2.8 -2.9 -2.9 -2.5
Heart attack 1.2 1.6 7.0 1.4 0.6 0.8 1.5 1.4 -0.7 1.1 1.2 1.5 1.3 -0.3 -1.1 1.1 1.6 1.3 0.4 1.6 2.7 1.0 0.7 0.7 1.4
Allergy 2.5 5.8 14.0 -2.5 -1.1 -2.8 -2.3 -2.1 -0.2 -3.4 -3.2 -3.0 -2.5 -1.6 1.9 -2.2 -2.6 -2.0 -1.7 -2.7 -0.9 -2.2 -3.7 -2.9 -2.4
Pain all over the body in last month 1.5 1.6 3.3 1.4 0.1 1.5 1.0 1.4 -1.4 1.4 0.6 1.6 1.2 0.9 -1.4 1.3 1.4 1.2 1.1 0.8 0.8 1.8 1.4 1.6 1.3
Diabetes (self-reported) 0.6 1.0 2.9 1.1 0.0 1.3 0.9 0.9 0.1 0.6 0.3 0.9 0.9 1.4 -1.0 0.2 1.7 0.6 1.2 0.5 1.2 1.0 1.3 1.4 1.0
Hayfever/allergic rhinitis (self-reported) 2.5 3.4 10.5 1.9 2.4 1.5 1.8 1.5 1.0 1.5 3.2 2.1 1.9 -0.9 -1.1 2.0 2.6 1.5 1.6 2.4 2.0 1.2 1.2 1.1 1.8
Medication: Ramipril 0.6 0.8 4.0 0.5 -0.7 0.8 0.3 0.6 -1.7 0.6 -0.7 0.8 0.4 0.1 -0.5 -0.2 1.7 0.2 0.6 0.5 1.6 2.0 0.8 1.0 0.4
Medication: Simvastatin 0.4 0.5 5.6 -0.1 -0.3 -0.0 0.1 0.2 -0.7 -2.4 -0.6 -0.5 -0.2 -0.8 -0.5 1.3 -0.4 -0.0 -0.9 -0.4 0.6 0.2 -0.6 -0.0 0.0
Fluid intelligence score 0.5 0.9 3.1 1.2 0.8 0.7 0.8 0.4 -1.1 -0.1 1.5 0.6 1.3 -0.6 -0.6 -1.5 -1.1 0.7 -1.8 1.3 0.0 0.9 0.1 -0.5 1.1
Illnesses of siblings 0.6 0.8 7.6 -0.8 -0.4 -0.7 -0.5 -0.6 1.1 1.1 0.1 -0.3 -0.8 2.8 0.7 -1.1 -0.0 -0.6 -0.2 -0.8 -0.9 -0.5 -0.6 -0.4 -0.8
Neuroticism score 0.5 1.0 7.8 -0.7 -2.8 -0.4 -0.5 -0.6 -0.6 -1.0 -1.0 -0.7 -0.5 -0.9 0.7 1.2 -1.5 -0.5 0.6 -0.9 -0.9 -1.4 0.4 -0.2 -0.7
Weight 1.9 9.5 16.2 4.0 2.6 3.5 3.8 3.9 0.4 2.3 1.8 3.9 4.0 1.2 -3.7 3.4 0.5 4.0 0.3 3.8 2.7 0.6 3.3 3.4 4.0
Impedance of arm (right) 0.9 4.1 10.3 -2.5 -1.2 -2.0 -2.4 -2.2 -2.2 -0.9 -0.7 -2.2 -2.5 -3.2 2.2 -2.8 0.3 -2.2 -0.9 -2.0 -0.4 -0.4 -2.2 -2.6 -2.5
Arm fat percentage (right) 1.3 5.0 8.8 2.6 2.2 2.3 2.6 2.8 -0.2 1.7 2.0 2.9 2.7 -0.6 -2.6 3.0 1.2 2.6 0.4 2.6 1.8 1.7 2.2 2.4 2.6
Trunk fat-free mass 0.7 4.2 7.5 2.7 1.4 2.5 2.4 2.4 0.8 1.5 0.6 2.4 2.6 2.0 -2.4 1.7 -1.1 2.7 0.2 2.3 1.6 -1.1 2.5 2.4 2.7
Hip circumference 0.9 3.9 7.7 2.6 2.1 1.9 2.7 2.6 0.5 1.2 0.8 2.3 2.7 0.4 -2.7 2.2 -0.1 2.8 -1.0 2.5 0.9 -0.2 1.9 1.8 2.8
Time employed in main current job 0.3 0.3 2.4 0.0 0.4 -0.3 0.2 0.4 -1.0 0.2 -0.4 0.2 0.1 -0.1 -0.6 0.1 -0.1 0.7 -1.5 0.0 -0.6 -0.2 -0.8 -0.7 0.1
Alcohol intake versus 10 years previously 2.1 3.2 6.7 2.3 1.6 1.8 2.5 2.0 -1.4 1.5 0.9 1.9 2.3 -1.6 -2.2 1.5 1.8 2.6 -1.1 2.0 1.1 0.2 1.6 0.7 2.3
Father’s age at death 1.0 1.4 4.5 -1.3 -0.8 -1.3 -1.7 -1.2 -1.1 0.4 0.1 -0.8 -1.2 1.9 1.3 -2.1 0.1 -1.2 1.0 -1.0 -0.7 0.6 -1.4 -1.0 -1.4
Worrier / anxious feelings 0.3 0.6 3.3 -0.3 -1.8 -0.9 -0.1 -0.4 -1.2 -1.0 -1.0 -0.2 -0.2 -0.0 0.6 1.2 0.1 -0.2 0.0 -0.4 -1.5 -0.4 0.1 -0.5 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 0.8 0.1 -0.7 0.4 0.0 0.1 -0.6 -0.6 -0.7 0.0 0.1 -0.1 -0.3 0.9 0.1 -0.0 0.9 0.2 0.3 0.2 -0.1 0.5 0.1
Falls in the last year 0.5 0.6 2.5 0.3 -0.0 0.3 0.4 0.8 -0.3 0.8 0.5 1.0 0.4 0.6 -0.5 1.6 0.8 0.5 1.5 0.5 0.0 1.5 0.6 1.2 0.3
Hair/balding pattern: Pattern 3 1.2 1.8 4.9 -1.1 -0.7 -0.9 -1.2 -1.8 -2.2 -0.7 -1.5 -1.5 -1.2 -0.6 1.3 -1.6 -1.2 -1.7 -0.4 -1.1 -0.8 -1.8 -1.2 -1.9 -1.1
Number of live births 0.5 0.7 4.7 -0.8 0.1 -0.7 -0.6 -0.5 0.3 0.0 -0.5 -0.7 -0.8 0.5 0.4 0.3 -2.2 -0.6 0.4 -0.9 0.1 -1.9 -0.9 0.1 -0.6
Forced expiratory volume in 1-second (FEV1) 0.8 2.8 8.3 -1.6 -0.4 -1.9 -1.9 -2.2 -0.4 -1.2 0.0 -1.7 -1.6 0.9 2.2 -2.6 -1.1 -1.6 -1.5 -1.3 -0.0 -1.3 -2.3 -2.9 -1.7
Pulse rate 1.7 2.9 6.7 -2.2 -2.6 -1.4 -2.0 -2.1 -2.1 -0.8 -1.6 -1.9 -2.1 0.2 1.7 -0.9 -0.7 -2.3 1.8 -2.3 -1.0 -1.6 -0.7 -0.3 -2.1
Happiness 0.6 0.7 2.9 -0.8 -1.7 -0.5 -1.1 -0.7 0.1 -1.1 -1.3 -0.7 -0.9 0.4 0.5 0.0 -0.9 -0.7 0.8 -1.0 0.3 -1.4 -0.9 -0.2 -0.7
Noisy workplace 1.0 1.2 3.6 0.8 0.3 1.6 0.8 0.8 -1.2 -0.2 0.9 0.7 0.8 -1.7 -1.3 1.5 1.9 1.1 0.1 0.7 1.7 0.5 1.2 1.2 0.8
Qualifications: A levels/AS levels or equivalent 3.8 8.4 15.1 -2.9 -2.4 -2.9 -2.7 -3.4 0.5 -3.7 -3.2 -3.9 -3.0 0.7 3.2 -3.6 -2.7 -3.1 -2.4 -2.8 -1.7 -3.1 -2.7 -3.3 -2.9
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.4 -0.2 -0.3 -1.1 -0.3 -0.5 0.3 0.2 0.3 -0.2 -0.3 0.6 0.5 -0.9 -0.2 -0.2 -0.6 -0.3 0.0 -0.3 -1.1 -1.2 -0.3
Mouth/teeth dental problems: Dentures 5.1 8.6 15.1 3.4 2.7 2.7 3.5 3.4 -0.9 3.8 2.4 3.9 3.5 -0.2 -3.4 2.6 2.8 3.6 0.1 3.8 1.7 2.4 3.2 2.6 3.3
Asthma 1.0 1.9 4.6 1.6 0.8 1.1 1.5 1.4 0.8 2.1 1.5 1.8 1.5 0.6 -1.5 0.8 1.4 1.5 0.4 2.2 0.5 1.2 1.6 1.3 1.6
Medication: Ibuprofen (e.g. Nurofen) 1.6 2.0 3.6 -1.4 -1.9 -1.7 -1.5 -1.6 0.0 -1.5 -1.0 -1.6 -1.3 -0.2 1.5 -1.5 -1.7 -1.6 -0.1 -1.8 -1.6 -1.0 -1.8 -1.3 -1.5
Medication: Cholesterol lowering 0.1 0.2 1.1 0.2 0.1 0.2 0.3 0.3 -0.2 -0.5 -0.2 -0.0 0.1 -0.7 -0.6 0.3 -1.0 0.4 -1.1 0.4 0.6 -0.3 0.3 0.1 0.3
Depression (self-reported) 0.5 0.6 3.0 -0.1 -0.7 -0.2 -0.1 0.0 -1.5 -1.7 -1.7 -0.5 -0.0 -0.4 0.0 -0.5 -0.9 -0.1 -0.1 -0.0 -1.2 -0.7 -0.7 -0.2 -0.1
Medication: Lansoprazole 2.5 2.8 5.2 -1.9 -1.5 -2.1 -1.7 -1.9 1.6 -1.6 -0.6 -2.0 -1.8 1.1 1.5 -1.3 -2.1 -1.2 -2.3 -1.9 -1.1 -1.3 -1.3 -2.2 -1.8
Prospective memory result 0.5 0.6 3.9 -0.1 -0.8 0.6 -0.1 0.1 -0.4 0.3 -0.2 0.1 -0.2 -0.3 0.0 2.0 1.3 0.0 1.5 -0.4 1.4 0.5 0.8 1.2 -0.2
Lung cancer (father) 2.4 2.8 10.2 1.4 0.6 1.3 1.3 1.4 -1.6 3.2 2.3 2.1 1.5 0.4 -1.0 1.1 1.7 0.8 2.7 1.6 1.2 2.0 1.5 2.1 1.3
Illnesses of mother 0.6 0.7 3.7 0.5 0.4 0.8 0.5 0.7 -0.3 1.9 1.6 0.9 0.4 0.0 -0.7 0.6 1.4 0.6 0.4 0.5 0.8 0.8 0.8 0.9 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.2 7.0 -1.1 0.2 -1.6 -1.2 -1.8 0.6 -1.4 0.3 -1.6 -1.1 0.9 1.6 -2.6 -0.9 -1.1 -2.6 -1.1 -0.7 -1.4 -1.8 -2.7 -1.2
Pulse wave Arterial Stiffness index 3.4 4.0 7.5 2.4 1.4 2.1 2.3 2.1 -0.7 0.5 1.5 2.0 2.3 1.9 -1.9 2.1 2.4 2.0 -0.7 2.4 2.7 2.2 2.0 1.9 2.4
Impedance of arm (left) 0.7 3.1 7.5 -2.2 -0.9 -1.7 -2.1 -1.9 -2.2 -0.4 -0.5 -1.9 -2.2 -2.7 1.8 -2.4 0.3 -1.9 -0.5 -1.8 -0.8 -0.2 -1.8 -2.3 -2.2
Arm fat mass (right) 1.7 7.0 11.7 3.3 2.3 2.9 3.3 3.4 -0.1 1.9 1.9 3.4 3.4 0.2 -3.2 3.4 0.8 3.3 0.5 3.2 2.1 1.2 2.9 3.0 3.3
Trunk predicted mass 0.8 4.3 7.6 2.7 1.5 2.5 2.5 2.4 0.8 1.6 0.7 2.4 2.6 2.0 -2.4 1.8 -1.0 2.7 0.3 2.4 1.6 -1.0 2.6 2.4 2.8
Standing height 0.2 2.4 6.3 1.9 1.1 2.0 1.6 1.6 -0.4 1.6 0.3 1.6 1.8 0.2 -1.6 -0.1 -0.9 2.1 -0.3 2.0 2.5 -1.7 1.8 1.2 2.0
Length of working week for main job 0.9 1.0 3.4 0.9 0.3 1.1 0.9 1.0 -0.6 -1.4 -0.8 0.5 0.9 0.3 -1.1 1.6 -0.6 1.0 1.2 0.7 0.7 -0.4 1.3 1.9 0.9
Exposure to tobacco smoke at home 0.3 0.4 3.1 0.4 0.4 0.3 0.5 0.3 -1.8 0.3 0.7 0.6 0.5 -1.6 -0.1 0.2 -0.2 0.3 0.1 0.6 0.0 0.2 0.3 -0.0 0.4
Breastfed as a baby 0.2 0.2 1.5 -0.2 0.0 -0.6 -0.2 -0.4 0.5 -0.9 -0.1 -0.6 -0.2 -0.8 0.1 -0.3 -1.2 -0.1 -0.5 0.2 -0.3 -0.3 -0.3 -0.5 -0.2
Tense / ‘highly strung’ 0.2 0.4 2.5 -0.3 -1.6 0.2 -0.3 0.1 -0.9 -0.6 -0.5 -0.4 -0.3 0.2 -0.3 1.4 -0.4 -0.1 0.6 -0.3 0.7 -1.0 -0.3 0.6 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.0 7.0 -0.8 -1.3 -0.9 -0.4 -0.8 -0.5 -1.9 -1.2 -1.0 -0.7 -1.0 0.8 -0.0 -1.0 -0.5 -0.2 -0.3 0.0 -2.6 -1.0 -1.0 -0.6
Hair/balding pattern: Pattern 4 0.8 1.9 4.2 1.2 1.6 2.0 1.3 1.7 1.0 0.5 1.3 1.4 1.4 0.2 -1.9 0.5 -0.4 1.8 -0.0 1.0 2.0 0.9 1.8 2.0 1.3
Birth weight of first child 0.2 0.3 1.7 -0.1 0.2 -0.5 -0.4 -0.4 -0.3 -0.2 0.2 -0.1 -0.1 1.3 0.1 -0.1 -0.2 0.1 0.2 0.9 1.1 -1.1 -0.0 -0.5 -0.1
Peak expiratory flow (PEF) 0.2 0.4 3.0 -0.2 0.6 -0.1 -0.3 -0.5 -1.1 -0.3 1.0 -0.2 -0.0 1.0 0.5 -0.9 0.3 -0.2 0.2 0.2 1.7 0.4 -0.8 -0.6 -0.3
Pulse wave reflection index 1.2 1.5 3.1 1.5 1.2 1.3 1.2 1.5 0.8 0.5 1.1 1.4 1.5 0.8 -1.3 0.2 0.8 1.8 -0.9 1.5 1.5 1.6 1.0 0.7 1.4
Ever highly irritable/argumentative for 2 days 0.3 0.4 4.0 -0.1 0.3 0.1 -0.1 -0.0 2.0 0.1 0.9 -0.1 -0.0 0.3 -0.4 1.6 -0.0 0.1 0.2 -0.3 -0.3 -0.8 0.1 0.3 0.0
Loud music exposure frequency 0.3 0.3 1.4 0.4 0.7 0.4 0.4 0.7 0.5 0.1 0.0 0.6 0.4 0.8 -0.6 0.8 0.4 0.6 -0.1 0.7 1.2 -0.3 -0.2 0.6 0.5
Qualifications: O levels/GCSEs or equivalent 4.1 6.6 16.5 -2.3 -2.3 -2.3 -2.4 -2.9 0.9 -3.4 -2.3 -3.1 -2.3 0.2 2.8 -4.1 -2.6 -2.4 -3.0 -2.5 -1.5 -2.2 -2.5 -3.2 -2.3
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.0 -0.2 -0.8 0.1 -0.4 -0.3 -0.6 0.6 0.5 0.1 -0.2 0.3 0.9 -0.4 1.0 -0.5 1.0 -0.8 -0.1 0.1 0.4 -0.3 -0.4
Blood clot in the leg (DVT) 0.6 0.7 1.8 1.0 0.9 0.9 0.8 0.8 0.3 0.9 0.6 0.8 0.9 1.2 -0.8 1.1 -0.4 0.7 -0.3 1.4 1.0 0.3 0.9 0.4 1.0
Medication: Paracetamol 0.9 1.5 4.7 -1.2 -2.2 -1.0 -1.5 -1.5 -0.6 -0.3 0.1 -1.0 -1.2 -1.5 1.6 -0.8 -1.3 -1.7 0.3 -1.0 -1.2 -0.7 -1.2 -1.5 -1.3
Headache pain in last month 0.3 0.6 2.4 -0.6 -1.6 0.5 -0.7 -0.3 1.3 -0.5 0.4 -0.5 -0.6 -0.6 0.8 0.4 -0.5 -0.7 1.5 -0.8 0.6 -0.2 0.3 1.1 -0.6
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 2.0 0.4 1.4 0.1 0.4 0.2 0.3 0.5 0.5 0.4 0.4 0.6 0.1 0.1 0.2 0.2 1.0 0.6 0.5 -0.0 -0.3 0.2 0.4
Glaucoma (self-reported) 0.3 0.4 1.3 -0.8 -1.0 0.0 -0.7 -0.7 0.5 0.3 0.5 -0.7 -0.8 -0.2 1.2 -0.2 -0.2 -0.8 0.1 -0.2 1.1 0.0 -0.2 -0.2 -0.8
Gout (self-reported) 1.1 1.5 4.7 -1.4 -1.7 -1.0 -1.6 -1.3 -1.4 -1.0 -1.1 -1.1 -1.3 1.2 0.9 -0.0 -0.3 -1.5 0.5 -1.6 -2.2 -0.6 -1.3 -0.6 -1.4
Hypothyroidism/myxoedema (self-reported) 1.7 3.4 17.8 1.1 1.1 0.2 1.2 0.8 1.3 -3.9 -2.9 -0.7 1.0 -0.3 -1.0 -0.5 -4.1 1.2 -4.2 0.7 -0.9 -1.3 0.3 -0.7 1.3
Medication: Amlodipine 1.3 1.8 4.2 1.7 0.8 1.5 1.5 1.9 -0.7 1.5 0.6 1.7 1.6 -0.8 -2.0 1.2 0.9 1.5 0.6 1.4 0.7 1.5 1.3 1.3 1.7
Medication: Ventolin 100micrograms inhaler 0.7 0.8 3.3 0.4 -0.3 0.9 0.2 0.7 -0.5 1.0 0.8 0.6 0.3 1.5 -0.7 1.2 1.7 0.5 1.1 0.3 0.6 0.6 1.4 1.8 0.4
Birth weight 0.7 1.5 11.0 -1.0 -1.1 -1.1 -0.9 -1.3 -0.1 -0.8 -1.8 -1.3 -1.0 0.1 0.9 -0.6 -1.5 -0.6 -0.8 -1.1 -0.7 -3.3 -1.0 -1.1 -0.9
Chronic bronchitis/emphysema (mother) 0.3 0.4 2.3 0.0 -0.3 0.2 0.3 0.2 1.3 0.3 -0.9 0.2 0.1 -0.3 0.3 1.0 -0.1 0.0 1.3 -0.1 -1.5 -0.2 0.2 0.6 0.0
High blood pressure (siblings) 0.4 0.6 8.8 -0.0 -0.8 -0.1 -0.3 -0.4 -0.6 -0.6 -0.6 -0.6 -0.2 -3.0 0.3 -0.0 -0.9 -0.3 -0.4 0.0 0.2 -0.9 -0.3 -0.7 -0.0
Forced vital capacity (FVC), Best measure 0.6 2.2 9.2 -1.0 0.1 -1.5 -1.2 -1.7 0.7 -0.9 0.1 -1.4 -0.9 1.0 1.4 -2.7 -1.4 -0.9 -3.0 -0.9 -1.0 -1.6 -1.7 -2.7 -1.1
Body fat percentage 2.9 11.3 19.2 4.1 3.3 3.5 4.1 4.2 -0.2 3.0 2.9 4.4 4.2 -0.5 -4.1 3.6 1.8 4.0 0.2 4.1 2.6 2.7 3.2 3.4 4.1
Leg fat percentage (right) 3.2 11.6 19.9 4.3 3.6 3.2 4.3 4.3 0.4 2.7 3.0 4.5 4.4 -0.3 -4.2 3.5 1.8 4.1 -0.7 4.4 2.4 3.0 2.6 3.0 4.3
Arm fat-free mass (right) 2.1 10.6 18.2 4.2 2.3 3.9 4.0 4.0 0.6 2.5 1.8 4.1 4.3 1.7 -3.8 3.5 0.1 4.2 1.0 3.8 2.3 0.6 3.9 3.9 4.3
Exposure to tobacco smoke outside home 0.3 0.4 1.7 -0.1 -0.2 0.1 -0.1 0.2 -0.0 1.3 0.7 0.3 -0.1 -0.7 0.1 0.8 -0.6 0.2 1.3 -0.7 -0.3 -1.2 0.3 0.3 -0.1
Comparative body size at age 10 0.3 0.9 6.0 0.5 0.8 0.9 0.6 0.4 0.6 -1.0 -0.6 0.1 0.5 -0.8 -0.6 0.8 -2.1 0.8 -1.1 0.6 0.9 -2.4 1.1 0.1 0.7
Number of full brothers 1.6 2.0 6.1 1.6 1.5 1.6 1.3 1.5 0.2 1.2 1.4 1.6 1.5 0.1 -1.0 1.5 0.7 1.3 0.2 1.8 2.5 1.8 1.5 1.5 1.5
Worry too long after embarrassment 0.6 1.1 7.3 -0.7 -2.7 0.0 -0.7 -0.5 -0.7 -0.8 -1.8 -0.7 -0.7 0.2 0.8 0.1 -1.3 -0.5 0.8 -1.3 -1.0 -1.5 1.0 0.5 -0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 4.2 -1.3 -2.0 -1.3 -1.3 -1.5 -0.6 -1.4 -1.0 -1.6 -1.2 -1.0 1.2 -1.2 -0.8 -1.2 -0.7 -1.2 -0.7 -1.9 -1.6 -1.7 -1.3
Wheeze or whistling in the chest in last year 2.6 4.7 8.1 2.4 2.2 2.7 2.0 2.4 -0.0 2.4 2.0 2.6 2.3 0.5 -2.5 1.7 1.6 2.3 0.8 2.8 2.4 2.1 2.7 2.5 2.4
Number of children fathered 0.5 0.6 1.9 -0.6 -1.1 -1.2 -0.7 -0.8 0.2 -1.4 -0.7 -1.0 -0.5 0.0 0.6 -0.8 -0.5 -1.0 -0.6 0.6 -0.2 -0.0 -1.2 -0.7 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 1.8 0.3 1.3 -0.2 0.1 0.1 -0.4 0.6 0.4 0.3 0.2 1.1 -0.4 0.7 0.1 0.3 -0.5 0.0 -1.4 -0.3 0.0 -0.2 0.3
Age at first live birth 1.4 2.5 4.7 -1.8 -1.0 -1.5 -2.2 -2.0 1.4 -0.9 -0.5 -2.1 -1.9 0.2 1.8 -1.9 -0.9 -1.9 -0.2 -1.9 -2.0 -1.2 -1.3 -1.8 -1.8
Pulse wave peak to peak time 3.1 3.6 7.0 -2.3 -1.4 -2.0 -2.2 -2.0 0.4 -0.4 -1.5 -1.8 -2.1 -1.7 1.8 -2.2 -2.3 -1.9 0.7 -2.3 -2.6 -2.3 -2.0 -1.8 -2.2
Health satisfaction 0.3 0.4 2.7 0.5 0.2 0.3 0.3 0.6 1.6 0.6 0.1 0.7 0.3 0.4 -0.6 0.3 -0.2 0.5 0.5 0.5 1.6 0.2 0.4 0.4 0.5
Shortness of breath walking on level ground 0.8 0.9 5.7 0.5 0.1 0.7 0.4 0.8 -0.8 0.4 -0.4 0.7 0.4 1.1 -0.5 1.3 0.7 0.4 2.4 0.8 1.6 1.0 0.8 1.6 0.5
Qualifications: College or University degree 2.4 7.5 16.7 -2.7 -2.5 -2.3 -2.8 -3.1 -1.4 -4.1 -3.4 -3.7 -2.8 0.5 2.7 -3.8 -2.2 -2.4 -1.8 -3.0 -1.3 -3.1 -2.3 -3.0 -2.6
Eye problems/disorders: None of the above 0.4 0.5 1.1 -0.8 -0.1 -1.0 -0.9 -0.9 -0.2 0.3 0.3 -0.7 -0.7 0.0 0.8 -0.7 -0.5 -0.7 0.8 -0.5 0.1 -1.0 -0.6 -1.0 -0.8
Mouth/teeth dental problems: Loose teeth 2.4 2.9 11.3 1.3 1.6 1.2 1.1 1.4 -0.8 2.3 3.1 1.9 1.2 0.8 -1.2 1.7 3.4 1.1 1.8 1.4 1.6 1.9 0.9 1.3 1.2
Emphysema/chronic bronchitis 0.4 0.4 2.0 -0.4 -1.4 -0.2 -0.6 -0.5 -0.9 -0.7 -0.4 -0.8 -0.6 -0.5 0.5 0.1 -1.0 -0.5 -0.2 -0.2 -0.2 -1.3 0.3 -0.0 -0.4
Medication for pain relief, constipation, heartburn 0.4 0.6 4.2 0.6 2.0 0.7 0.8 0.9 0.6 -0.3 0.2 0.6 0.7 0.6 -0.9 0.3 0.8 1.2 0.1 0.7 0.9 -0.1 0.7 0.9 0.7
Neck or shoulder pain in last month 0.3 0.4 1.7 -0.4 -1.3 0.4 -0.2 -0.3 0.8 0.9 -0.2 -0.2 -0.2 0.4 0.5 0.5 -0.9 -0.6 0.5 -0.4 -1.0 0.2 1.3 0.4 -0.4
Medication: Blood pressure 0.3 0.6 2.8 0.4 -0.8 1.0 0.5 0.9 -0.6 0.2 -0.3 0.6 0.4 -0.5 -1.0 0.9 1.3 0.8 -0.0 -0.1 -0.5 0.8 1.7 1.2 0.4
Angina (self-reported) 0.3 0.4 3.0 0.2 -1.3 0.1 0.1 0.2 -1.7 0.2 -0.5 0.2 0.3 -1.0 -0.3 -0.6 -1.2 0.4 -0.6 -0.1 0.4 0.1 0.6 -0.3 0.3
Migraine (self-reported) 0.9 1.2 11.8 -0.2 -0.5 0.7 -0.0 0.4 -0.3 1.3 1.1 0.3 -0.2 -0.6 0.3 0.2 1.7 -0.3 3.4 -0.7 1.0 0.7 1.1 1.8 -0.2
Medication: Ibuprofen 1.2 1.4 2.9 -1.1 -1.2 -1.5 -1.2 -1.2 -0.8 -1.6 -0.9 -1.3 -1.0 -0.0 1.1 -1.0 -1.5 -1.3 -0.5 -1.5 -1.3 -0.9 -1.7 -1.1 -1.1
Medication: Allopurinol 1.2 1.7 3.9 -1.5 -1.2 -1.3 -1.4 -1.6 -1.9 -1.2 -0.3 -1.4 -1.3 0.2 1.3 -0.3 0.6 -1.6 -0.9 -1.2 -2.0 0.2 -1.6 -1.5 -1.5
Medication: Omeprazole 1.5 1.8 4.9 1.3 1.0 0.9 1.5 1.4 0.4 0.8 1.4 1.6 1.4 0.9 -1.6 1.4 1.9 1.3 -1.6 1.6 0.6 2.2 0.9 0.7 1.3
Medication: Seretide 50 evohaler 0.6 0.7 4.6 -0.6 0.2 -0.6 -0.6 -0.5 0.6 -1.3 -0.5 -0.8 -0.8 2.1 0.5 -0.9 1.1 -0.5 -1.0 -0.1 -0.5 0.7 -0.7 -0.8 -0.6
Mean time to correctly identify matches 0.5 1.0 4.0 0.7 1.9 1.0 0.8 0.8 0.0 0.9 0.8 0.5 0.8 -2.0 -1.3 0.4 -1.0 1.2 -0.8 1.0 -0.4 -0.5 1.4 0.3 0.9
Heart disease (mother) 1.1 1.4 4.8 -0.6 -0.4 -1.0 -0.6 -0.9 0.4 -2.0 -1.3 -1.2 -0.5 -0.5 0.7 -1.9 -1.9 -0.5 -2.2 -0.3 0.2 -1.2 -1.6 -1.6 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.5 1.8 7.2 1.1 1.9 1.1 1.1 1.5 0.7 0.5 1.2 1.4 1.1 1.7 -1.0 1.2 0.9 0.8 2.7 0.9 0.6 1.8 1.1 2.2 1.1
Whole body fat mass 2.9 12.0 19.8 4.3 3.2 3.9 4.2 4.4 0.0 3.0 2.7 4.4 4.4 0.2 -4.2 3.8 1.1 4.3 0.4 4.2 2.6 1.9 3.7 3.7 4.3
Leg fat mass (right) 3.0 11.7 20.2 4.4 3.2 3.6 4.3 4.4 0.1 2.8 2.6 4.5 4.5 0.2 -4.2 3.6 1.3 4.3 -0.2 4.4 2.6 2.0 3.3 3.4 4.4
Arm predicted mass (right) 2.1 10.5 18.1 4.2 2.4 3.8 4.0 4.0 1.0 2.6 1.7 4.1 4.2 1.8 -3.8 3.4 -0.2 4.2 0.9 3.8 2.3 0.4 3.9 3.9 4.3
Pulse rate, automated reading 1.2 3.8 11.6 -2.4 -3.4 -1.3 -2.3 -2.3 -1.5 -1.2 -1.4 -2.3 -2.5 0.5 2.2 -0.4 -0.2 -2.9 2.4 -2.7 -0.3 -1.8 -1.1 0.1 -2.4
Alcohol intake frequency. 3.5 8.2 15.6 3.7 2.0 3.3 4.0 3.7 0.7 1.5 1.8 3.1 3.8 -2.3 -3.1 2.6 1.2 3.8 -0.7 3.7 2.8 1.8 3.3 2.6 3.7
Comparative height size at age 10 0.7 3.7 7.8 2.4 2.4 1.9 2.1 1.7 -1.5 2.1 1.4 2.1 2.3 -0.3 -1.9 0.1 -1.1 2.5 -2.7 2.8 1.6 -1.6 1.8 0.3 2.5
Number of full sisters 0.6 0.8 1.7 0.9 0.8 0.1 1.0 1.0 0.7 0.8 0.7 1.0 0.8 1.3 -1.1 0.1 1.3 1.2 -0.7 1.0 0.8 0.7 0.4 0.4 0.9
Suffer from ‘nerves’ 0.3 0.5 2.4 0.5 -0.9 0.3 0.4 0.5 0.6 -1.3 -0.1 0.2 0.6 0.9 0.0 1.5 -0.4 0.3 1.1 0.7 0.2 -0.4 0.7 0.6 0.4
Overall health rating 1.0 2.2 4.6 1.7 0.2 1.7 1.6 1.8 0.4 0.0 0.4 1.7 1.7 -0.7 -1.5 2.0 0.8 1.7 1.4 1.2 1.7 1.5 2.2 1.9 1.7
Chest pain or discomfort 0.5 0.7 3.3 0.4 -0.4 0.8 0.3 0.7 -0.2 0.8 -0.2 1.0 0.5 0.5 -0.8 0.4 0.2 0.8 1.6 0.3 0.2 1.1 1.8 1.5 0.4
Had major operations 0.4 0.5 1.3 -0.7 -1.1 -0.9 -1.0 -0.6 -0.6 -0.3 -0.2 -0.9 -0.9 0.8 0.8 -1.1 -0.4 -0.9 0.4 -0.5 -0.4 0.4 -0.3 -0.5 -0.8
Age at last live birth 2.2 3.2 6.3 -2.3 -1.5 -1.7 -2.5 -2.2 0.5 -1.2 -1.0 -2.4 -2.2 -0.6 2.0 -1.4 -2.0 -2.1 0.9 -2.2 -2.2 -1.8 -0.9 -1.3 -2.3
Family relationship satisfaction 0.7 0.9 4.8 -0.1 0.1 0.1 0.0 0.0 1.9 1.2 0.4 0.5 0.0 2.2 -0.1 1.5 1.3 -0.1 2.1 0.0 0.5 0.5 -0.1 0.8 -0.1
Leg pain on walking 0.3 0.3 1.4 -0.1 -0.3 -0.1 -0.2 0.0 -0.5 -0.3 -1.1 0.1 -0.3 0.4 0.2 1.0 -0.7 -0.1 1.2 0.3 1.2 -0.6 0.2 0.7 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 4.0 0.5 0.2 1.2 0.6 1.0 -0.5 0.4 -0.4 0.9 0.5 0.4 -0.6 1.0 1.7 0.3 2.0 -0.2 0.3 1.4 0.8 2.0 0.3
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.3 0.7 0.6 -0.1 0.9 0.6 0.8 0.3 0.2 0.5 0.8 1.3 -0.5 0.9 0.5 0.8 0.4 1.5 1.5 0.6 -0.0 0.2 0.7
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 7.3 -0.7 0.4 0.2 -0.4 -0.1 -1.0 2.0 1.3 0.6 -0.6 -0.2 0.0 1.5 2.5 -0.3 2.7 -0.3 -0.3 0.8 0.4 1.0 -0.7
Medication: Aspirin 0.1 0.2 0.7 0.3 -0.8 0.4 0.2 0.2 -0.7 0.5 -0.7 0.2 0.2 -0.1 -0.0 0.4 -0.3 0.0 0.2 0.3 0.7 0.4 0.1 0.1 0.3
Supplements: Vitamin C 0.8 0.9 3.3 1.1 1.8 0.6 1.2 1.0 1.1 0.2 0.8 0.8 1.1 -0.4 -1.0 0.7 -1.0 1.2 -1.2 1.4 0.1 -0.0 0.6 0.0 1.1
Knee pain experienced in last month 0.8 1.2 7.5 -1.2 -1.5 0.0 -1.3 -0.6 0.4 0.6 -0.8 -0.1 -1.0 1.5 0.8 1.0 0.6 -0.7 2.7 -1.2 -0.5 -0.7 1.0 1.2 -1.2
Hypertension (Self-reported) 0.3 1.0 3.4 0.6 -1.5 1.4 0.3 1.0 -1.0 -0.3 -1.0 0.7 0.5 -0.7 -1.1 1.0 0.6 0.7 1.3 -0.5 0.2 0.9 1.6 1.8 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 6.5 -0.4 -0.7 -0.7 -0.3 -0.7 0.8 -0.4 -0.0 -0.8 -0.4 -0.0 0.7 -0.9 -0.8 -0.4 -2.6 -0.4 -0.1 -1.0 0.1 -1.1 -0.4
Illnesses of father: Heart disease 1.2 1.7 4.5 1.5 1.8 1.4 1.4 1.1 -0.8 -0.4 1.1 0.7 1.6 -1.7 -1.9 -0.6 -0.2 1.4 -2.1 1.2 0.5 1.9 0.8 0.1 1.5
Illnesses of siblings: Diabetes 1.7 2.1 6.7 1.7 1.7 1.3 1.6 1.6 -2.6 -0.5 0.6 1.3 1.8 0.2 -1.8 0.3 0.3 1.8 -0.7 1.9 1.3 1.6 1.9 1.0 1.6
Smoking status: Previous 0.4 0.6 4.5 -0.4 -0.4 -0.4 -0.2 -0.4 -0.4 -0.3 -0.4 -0.4 -0.3 2.1 -0.3 0.4 -0.2 -0.3 -0.5 -0.2 -2.0 -1.3 -0.4 -0.2 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 3.7 -0.5 -0.1 -0.5 -0.6 -0.5 0.1 -0.2 0.3 -0.3 -0.5 0.7 0.7 -0.0 -0.3 -0.2 -0.2 -0.5 -0.6 -1.9 -0.5 -0.6 -0.4
Whole body fat-free mass 0.9 5.2 8.9 2.9 1.4 2.8 2.7 2.7 0.5 1.9 0.8 2.8 2.9 1.9 -2.6 2.1 -0.8 3.0 0.5 2.5 1.7 -0.7 2.9 2.8 3.0
Leg fat-free mass (right) 0.7 3.9 8.3 2.4 1.0 2.5 2.1 2.3 0.6 1.7 0.7 2.4 2.4 1.8 -2.0 2.1 -0.5 2.5 1.1 2.0 1.5 -0.8 2.9 2.6 2.4
Arm fat percentage (left) 1.6 6.3 10.8 2.9 2.4 2.7 3.0 3.2 -0.4 2.1 2.2 3.3 3.1 -0.5 -2.9 3.2 1.5 2.9 0.8 2.9 1.6 2.1 2.6 2.7 2.9
Average weekly red wine intake 2.4 3.6 7.8 -2.0 -1.3 -2.2 -1.9 -2.1 0.5 -1.4 -1.9 -2.3 -2.0 0.6 1.7 -1.4 -2.8 -1.9 -1.6 -1.7 -2.1 -2.3 -2.1 -2.3 -1.8
Handedness (chirality/laterality): Left-handed 1.9 2.3 4.8 1.9 1.0 2.1 2.2 1.7 1.5 0.9 0.9 1.4 1.9 0.9 -1.2 1.1 1.1 1.5 1.3 1.8 1.7 0.9 1.9 1.8 1.8
Mood swings 0.2 0.4 2.7 -0.3 -1.6 0.2 -0.1 -0.3 -0.7 -0.3 -0.7 -0.2 -0.1 -1.0 0.5 1.0 -0.7 -0.4 0.5 -0.8 -0.1 -0.7 0.7 0.2 -0.4
Loneliness, isolation 0.7 0.9 4.4 0.9 -0.3 0.9 0.8 0.8 -0.1 0.3 1.4 1.1 1.0 -0.2 -0.4 2.1 1.0 0.7 0.6 1.0 1.3 0.8 1.2 0.8 0.8
Long-standing illness, disability or infirmity 0.8 1.3 3.2 1.6 -0.2 1.5 1.4 1.3 0.3 -0.5 0.3 0.8 1.5 1.1 -1.3 0.3 0.7 1.1 -0.1 1.0 0.4 1.8 1.6 1.3 1.5
Ever had bowel cancer screening 0.2 0.2 0.6 0.4 0.4 0.2 0.4 0.3 -0.1 0.7 -0.0 0.5 0.3 0.8 -0.3 0.7 0.4 0.5 0.1 0.5 0.8 -0.3 0.4 0.4 0.5
Diabetes diagnosed by doctor 0.5 0.9 2.0 1.0 0.4 1.4 0.9 1.0 0.6 0.2 -0.1 0.8 0.8 1.2 -1.2 0.4 1.0 0.9 0.9 0.4 1.3 0.8 1.4 1.3 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 5.2 -0.6 -1.4 -1.1 -0.7 -0.5 -2.3 -0.1 -0.1 -0.4 -0.6 0.6 0.9 0.0 2.0 -0.8 1.0 0.0 -0.5 0.6 -0.8 -0.3 -0.8
Friendships satisfaction 0.4 0.5 2.2 0.2 -1.3 0.4 0.2 -0.0 -0.8 0.0 -0.8 0.3 0.3 1.2 -0.0 1.2 0.4 -0.2 1.5 0.1 0.9 0.1 0.3 0.8 0.1
Qualifications: nursing, teaching 2.2 3.4 8.0 -1.3 -0.9 -1.8 -1.5 -1.8 1.2 -2.4 -1.8 -2.3 -1.5 -0.7 2.0 -1.9 -2.8 -1.6 -2.4 -0.9 0.0 -2.2 -2.8 -2.6 -1.3
Commuting to job workplace: Walk 0.6 0.6 2.8 0.5 0.1 1.1 0.4 0.8 -0.9 -0.1 0.7 0.8 0.4 -0.5 -0.6 0.8 0.9 0.4 1.0 -0.1 0.7 0.9 1.7 1.0 0.4
Eye problems/disorders: Cataract 2.1 2.4 4.9 1.8 1.9 1.8 2.1 1.8 1.2 0.2 0.5 1.6 1.8 -0.1 -2.1 2.2 1.1 2.0 -1.1 1.2 0.2 0.9 1.9 1.4 1.9
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 5.4 -1.2 -0.4 -0.7 -0.8 -0.6 -0.3 -0.4 -0.9 -0.6 -1.0 2.3 0.3 0.9 -0.8 -0.7 1.6 -1.3 -1.0 -0.5 -0.5 0.7 -1.0
Medication for cholesterol 0.7 1.0 4.8 -1.1 0.4 -1.2 -1.1 -1.0 -0.3 2.2 2.0 -0.1 -1.0 -0.6 0.9 -1.2 0.8 -0.6 0.8 -0.5 -0.2 -1.2 -0.4 -0.7 -1.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.6 -0.6 -1.1 -0.1 -0.9 -0.7 -0.7 0.7 1.3 -0.3 -0.6 -1.3 0.4 -0.3 0.4 -0.4 1.1 -0.1 0.3 -0.1 0.4 -0.5 -0.6
Back pain experienced in last month 0.3 0.4 2.8 0.1 -0.5 0.4 -0.0 0.4 0.3 -0.2 0.5 0.4 0.2 1.7 -0.3 0.8 -0.2 0.3 1.4 0.1 0.7 0.5 0.7 1.0 0.1
Mineral and other dietary supplements 0.3 0.4 2.0 0.7 -1.4 0.4 0.3 0.6 -0.8 -0.3 -1.0 0.5 0.5 -1.0 0.0 0.6 0.6 0.4 0.9 0.4 -0.2 0.3 0.1 0.3 0.6
Breast cancer (self-reported) 0.6 0.7 4.8 -0.7 -0.2 -0.6 -0.6 -0.6 -0.4 1.0 0.4 -0.1 -0.8 2.2 0.7 0.6 1.6 -0.8 1.1 -0.1 0.2 0.4 -0.5 -0.2 -0.7
Asthma (self-reported) 1.1 2.2 5.1 1.7 1.0 1.3 1.6 1.5 0.6 2.1 1.7 1.9 1.6 0.4 -1.6 0.8 1.6 1.6 0.3 2.3 0.7 1.4 1.8 1.4 1.7
Osteoporosis (self-reported) 4.5 5.6 15.1 -2.0 -1.7 -2.4 -2.1 -2.4 -1.6 -2.6 -1.7 -2.7 -2.0 -1.9 1.9 -3.1 -1.9 -2.1 -3.9 -2.6 -2.5 -1.8 -2.9 -3.2 -2.0
Osteoarthritis (self-reported) 1.9 2.4 8.9 0.8 1.3 1.5 0.8 1.0 1.5 1.9 2.2 1.7 0.9 0.6 -1.1 2.0 2.3 0.5 3.0 0.8 1.4 2.0 1.2 2.1 0.8
Medication: Aspirin 0.1 0.2 1.2 0.1 -1.0 0.1 -0.0 -0.0 -1.1 0.3 -0.8 0.1 0.2 -0.3 0.2 0.2 -0.2 -0.1 0.3 0.3 0.7 0.3 -0.0 -0.3 0.1
Medication: Gliclazide 0.2 0.2 1.5 0.1 -0.1 0.6 0.3 0.3 -0.4 0.7 0.2 0.4 0.1 0.1 -0.1 0.3 1.2 0.1 0.8 -0.5 -0.1 0.2 0.5 0.6 0.1
Illnesses of father: None of the above (group 1) 0.9 1.1 4.9 -1.1 -0.1 -0.9 -1.0 -0.9 -0.9 0.5 0.3 -0.6 -1.3 0.9 0.7 1.6 0.7 -1.2 2.2 -0.6 -0.5 -2.0 -0.5 0.3 -1.0
Smoking status: Current 0.7 1.1 4.5 1.0 1.3 0.7 0.8 1.1 -0.8 1.4 0.6 1.1 0.9 -0.9 -0.8 0.6 1.1 0.8 1.4 0.9 2.1 0.6 0.2 1.1 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 4.7 -1.9 -0.5 -1.5 -1.8 -2.2 0.4 -1.5 -0.8 -1.8 -1.8 0.1 2.0 -1.5 -1.0 -2.1 -0.3 -1.9 -1.6 -1.0 -1.7 -1.7 -1.9
Whole body water mass 1.0 5.5 9.5 3.0 1.6 2.9 2.8 2.8 0.5 1.9 1.0 2.9 3.0 2.0 -2.7 2.3 -0.6 3.1 0.6 2.6 1.8 -0.5 3.0 2.9 3.1
Leg predicted mass (right) 0.7 3.9 8.4 2.3 1.0 2.5 2.1 2.3 0.5 1.7 0.8 2.4 2.4 1.7 -2.1 2.1 -0.5 2.5 1.1 2.0 1.5 -0.8 2.9 2.6 2.4
Arm fat mass (left) 1.9 7.9 13.1 3.5 2.5 3.1 3.4 3.6 -0.0 2.2 2.1 3.6 3.6 0.3 -3.4 3.6 0.9 3.5 0.8 3.3 2.0 1.4 3.0 3.3 3.5
Number of self-reported non-cancer illnesses 0.3 0.6 1.7 0.8 -0.7 1.0 0.6 0.7 -0.1 -1.3 -0.8 0.1 0.6 -1.0 -0.9 -0.1 -0.7 0.7 -0.3 0.1 0.2 0.1 1.3 0.9 0.9
Average weekly champagne plus white wine intake 1.1 1.6 5.7 -1.5 -0.9 -0.5 -1.2 -1.1 -1.3 -1.3 -1.3 -1.3 -1.4 1.3 0.8 0.7 -0.9 -1.3 1.3 -2.1 -2.4 -0.9 -0.0 0.3 -1.4
Miserableness 0.5 0.9 3.2 0.4 -1.5 1.4 0.4 0.6 -0.4 1.0 0.2 0.8 0.5 -1.0 -0.1 1.4 -0.1 0.4 1.8 -0.2 -0.6 -0.4 1.8 1.3 0.4
Guilty feelings 0.4 0.6 4.8 0.0 -2.2 0.7 -0.0 -0.1 -0.5 0.4 -0.1 0.2 0.2 -1.6 0.2 0.7 -0.1 -0.2 1.2 -0.5 -0.3 0.4 1.2 0.6 -0.1
Wears glasses or contact lenses 2.4 2.8 7.5 2.0 2.7 1.8 2.0 1.7 0.9 0.6 1.7 1.8 2.0 0.1 -2.0 0.8 1.1 1.7 -0.3 2.0 1.1 2.5 1.6 1.3 1.9
Ever taken oral contraceptive pill 0.7 0.7 3.3 0.9 1.0 0.2 1.0 0.3 -1.1 -0.5 -0.2 0.2 1.0 1.3 -1.1 0.3 0.8 0.5 -1.8 1.2 -0.3 0.7 0.2 -0.5 0.9
Hearing aid user 1.0 1.1 2.6 0.9 1.0 0.9 1.6 1.1 -0.1 0.6 1.6 1.0 1.3 -0.4 -1.6 0.8 0.9 1.3 -1.2 1.1 0.5 0.6 1.2 0.3 1.0
Mother’s age at death 0.4 0.5 1.4 -0.7 -0.2 -0.5 -0.8 -0.6 -0.7 -0.4 -0.3 -0.7 -0.6 0.9 0.9 -0.8 -1.1 -0.8 0.5 -1.1 -1.2 0.1 -0.2 -0.2 -0.8
Financial situation satisfaction 1.9 2.4 4.9 -1.9 -2.2 -1.5 -2.0 -1.7 0.5 -1.2 -1.7 -1.8 -1.9 1.0 1.7 -0.2 -0.9 -2.0 2.0 -1.6 0.7 -1.1 -1.4 -0.6 -1.9
Tinnitus: Yes, now most or all of the time 1.0 1.2 5.3 1.2 0.6 0.7 1.1 0.8 -1.0 1.1 1.5 1.4 1.3 1.0 -0.7 1.0 1.7 0.4 0.1 1.4 -0.2 2.3 0.5 0.7 1.0
Commuting to job workplace: Public transport 0.6 0.8 2.1 -1.0 -0.2 -0.1 -1.2 -0.8 0.7 -0.6 -1.0 -1.1 -1.2 0.2 0.5 -0.9 -1.4 -1.0 -0.0 -1.4 -0.8 -1.1 -0.4 -0.6 -0.9
Eye problems/disorders: Glaucoma 0.6 0.7 1.6 -1.0 -1.3 -0.1 -1.2 -0.8 1.0 0.5 0.8 -0.7 -1.1 -0.1 1.2 -0.4 -0.1 -1.0 0.7 -0.5 1.1 0.1 -0.5 0.1 -1.1
Medication: Blood pressure 0.3 0.5 2.5 0.7 -0.1 1.0 0.9 1.0 0.0 -0.5 -1.6 0.6 0.7 0.6 -1.1 0.7 -0.5 0.9 0.1 0.2 0.4 0.4 0.6 0.7 0.8
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.2 -0.1 0.3 0.7 -0.1 0.1 0.5 0.7 1.4 0.0 -0.2 0.7 -0.1 1.1 -0.1 -0.4 1.5 -0.6 0.7 0.2 0.8 1.1 -0.2
Supplements: Fish oil (including cod liver oil) 0.3 0.4 3.8 0.1 1.9 0.2 0.4 0.1 1.0 0.6 1.2 0.2 0.1 -0.3 -0.3 0.1 -0.4 0.4 -0.8 0.1 -0.0 -0.6 0.8 -0.0 0.2
High cholesterol (Self-reported) 0.5 0.8 4.0 -0.9 -1.1 -1.3 -0.6 -0.7 -0.5 -2.0 -1.1 -0.9 -0.8 0.2 0.4 1.1 -1.1 -0.7 -0.3 -0.8 -0.6 -0.8 -1.3 -0.6 -0.7
Medication: Bendroflumethiazide 0.4 0.7 2.0 0.7 0.6 0.6 0.7 0.9 -0.8 1.3 0.5 1.0 0.7 -0.4 -1.1 -0.7 0.8 0.9 -1.0 0.9 0.5 1.4 0.3 0.3 0.7
Medication: Paracetamol 0.6 0.9 2.4 -0.8 -1.6 -0.6 -1.0 -1.0 -0.6 -0.5 0.3 -0.8 -0.9 -1.2 1.0 -0.7 -1.1 -1.2 -0.4 -1.0 -0.5 -0.9 -1.0 -1.3 -0.8
Medication: Lisinopril 0.4 0.5 2.3 0.7 -0.2 0.3 0.7 0.5 -0.6 -0.9 -1.2 -0.1 0.6 -0.3 -0.9 0.7 -1.5 0.8 -1.0 0.4 0.1 -1.0 0.6 0.2 0.8
Medication: Atorvastatin 0.5 0.7 2.6 -0.9 -0.9 -0.8 -1.1 -0.8 -0.4 -0.2 -0.9 -0.7 -0.9 0.9 0.7 -1.6 -0.9 -0.7 -0.1 -1.0 -0.3 -0.8 -0.6 -0.2 -0.9
Illnesses of father: High blood pressure 0.2 0.2 0.7 -0.4 -0.6 -0.1 -0.6 -0.2 -0.8 -0.2 -0.1 -0.2 -0.4 -0.7 0.6 -0.8 -0.7 -0.1 -0.2 -0.6 -0.0 -0.5 -0.3 -0.3 -0.4
Alcohol drinker status: Never 1.0 1.2 3.0 0.8 0.0 1.2 0.8 1.3 -0.0 1.1 1.2 1.3 1.0 -0.7 -1.0 0.8 1.7 1.1 1.2 0.6 0.4 1.7 1.3 1.6 0.9
Ever smoked 0.1 0.2 1.3 -0.2 0.6 -0.3 -0.0 -0.2 -0.5 0.2 -0.2 -0.1 -0.1 0.9 -0.6 0.2 -0.1 0.0 -0.8 0.0 -0.4 -1.1 -0.6 -0.7 -0.0
Basal metabolic rate 1.1 6.3 11.2 3.2 1.8 3.0 3.0 3.1 0.6 2.0 1.1 3.1 3.2 1.7 -3.0 2.5 -0.5 3.3 0.4 2.9 1.9 -0.4 3.0 3.0 3.3
Leg fat percentage (left) 3.7 13.3 22.6 4.5 3.8 3.6 4.6 4.6 0.4 3.1 3.2 4.8 4.6 -0.3 -4.4 3.8 2.2 4.4 -0.2 4.6 2.9 3.0 3.1 3.4 4.5
Arm fat-free mass (left) 1.7 8.8 15.8 3.9 2.3 3.4 3.7 3.7 0.7 2.2 1.6 3.7 3.9 1.6 -3.5 3.0 -0.2 3.9 0.4 3.6 2.5 0.0 3.4 3.4 4.0
Number of operations (self-reported) 0.7 1.0 2.9 0.5 -0.0 0.8 0.2 0.5 -0.7 1.4 1.0 0.7 0.3 1.7 -0.3 0.6 1.7 -0.1 1.7 0.7 1.4 1.6 1.1 1.0 0.4
Average weekly beer plus cider intake 0.9 1.3 3.6 1.0 1.0 1.2 1.0 1.0 0.6 1.4 1.9 1.2 0.9 -0.1 -0.9 0.5 1.9 0.9 1.2 1.2 1.2 0.4 1.2 1.2 1.0
Irritability 1.7 2.8 6.0 2.2 1.4 1.8 2.3 2.1 -0.2 -0.7 -0.1 1.5 2.3 -0.8 -2.4 2.3 -0.6 2.4 -1.3 2.0 0.2 0.4 1.9 1.2 2.3
Risk taking 1.6 2.3 5.1 -1.8 -2.0 -1.5 -1.9 -1.9 -0.6 0.1 -1.0 -1.7 -1.7 0.3 2.3 -1.5 -0.8 -2.2 2.2 -1.8 -0.7 -1.4 -0.9 -0.5 -1.9
Ever had prostate specific antigen (PSA) test 6.2 7.1 13.5 -3.0 -1.5 -3.6 -2.7 -3.4 0.4 -2.8 -1.6 -3.3 -2.8 1.9 2.9 -2.1 -2.2 -2.9 -1.9 -2.3 -2.3 -2.2 -3.7 -3.6 -2.9
Fractured/broken bones in last 5 years 0.3 0.4 1.8 0.0 -0.4 0.1 -0.3 0.1 -0.5 1.2 1.3 0.3 -0.1 -0.2 -0.1 -1.0 0.8 0.2 -0.2 0.5 1.1 1.1 -0.2 0.2 -0.0
Age started oral contraceptive pill 0.5 0.6 1.8 0.6 1.1 0.7 0.9 0.6 0.8 -0.4 0.0 0.3 0.7 -1.1 -1.0 0.5 -1.3 0.7 -1.1 0.9 0.0 -0.2 1.0 0.4 0.8
Diastolic blood pressure, automated reading 0.8 2.4 7.0 -1.7 -1.6 -1.7 -1.8 -1.5 -0.7 -1.6 -2.1 -1.7 -1.7 0.4 1.1 -0.3 -1.3 -1.7 0.7 -2.0 -2.6 -1.7 -1.7 -1.1 -1.6
Ever depressed for a whole week 0.1 0.2 0.9 -0.2 -0.4 -0.1 0.1 -0.0 -0.9 0.5 0.4 0.3 0.0 0.2 -0.7 0.9 0.1 0.2 0.2 0.2 -0.4 -0.1 -0.3 -0.3 -0.1
Unable to work because of sickness or disability 2.2 2.8 7.7 1.5 1.2 1.3 1.6 2.0 -0.9 0.7 2.1 1.8 1.7 0.0 -2.1 2.0 2.8 2.2 0.9 2.0 1.2 2.2 1.2 1.6 1.5
Commuting to job workplace: Cycle 0.4 0.5 2.5 -0.5 -0.7 0.1 -0.5 -0.4 1.0 0.4 1.3 -0.2 -0.3 -1.6 0.7 0.1 1.2 -0.5 -0.2 -0.9 -0.7 0.4 0.0 -0.4 -0.6
Myopia 0.6 0.9 7.6 -0.6 1.2 -0.4 -0.5 -0.4 2.8 0.8 -0.2 -0.6 -0.7 1.2 0.2 -1.8 -0.4 -0.4 0.4 -0.5 -0.3 -0.7 -0.7 -0.5 -0.5
Vascular/heart problems diagnosed by doctor 0.5 1.3 3.5 -0.9 1.3 -1.5 -0.7 -1.4 1.5 0.6 1.0 -0.9 -0.8 0.6 1.4 -1.1 -0.6 -1.1 -0.9 0.1 -0.7 -1.2 -1.7 -1.9 -1.0
Cholesterol lowering medication 0.3 0.4 3.5 0.1 -0.8 -0.0 -0.0 0.2 -0.9 -1.9 -1.0 -0.2 0.0 0.1 -0.2 1.0 -1.0 -0.0 -0.2 -0.3 -0.3 0.9 -0.5 0.1 0.1
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 3.8 0.6 0.8 -0.1 0.7 0.5 0.9 -0.2 0.9 0.8 0.7 1.1 -1.0 0.4 1.5 0.7 -2.0 1.1 0.1 1.9 0.0 -0.2 0.6
Pain experienced in last month 0.7 1.2 7.8 -0.1 1.2 -1.5 -0.1 -0.4 -0.6 -1.3 -0.4 -0.7 -0.2 0.1 0.4 -1.5 0.2 -0.3 -2.8 0.3 -0.7 0.2 -2.3 -1.8 -0.1
Supplements: Calcium 4.0 4.4 9.7 -1.9 -0.8 -2.5 -2.3 -2.3 0.3 -2.8 -0.5 -2.5 -2.0 -0.2 2.0 -2.5 -3.1 -2.1 -2.2 -1.4 -0.9 -2.1 -3.1 -2.9 -1.8
Basal cell carcinoma (self-reported) 0.3 0.4 1.9 -0.4 -0.5 -0.3 -0.5 -0.5 -0.7 0.9 0.4 0.0 -0.4 0.3 0.9 -0.0 1.4 -0.6 1.3 -0.2 -0.5 0.4 0.2 -0.0 -0.5
Heart attack/myocardial infarction (self-reported) 1.3 1.7 6.6 1.5 0.6 0.9 1.6 1.5 -0.6 1.0 1.1 1.6 1.4 0.0 -1.2 1.2 1.6 1.4 0.5 1.6 2.6 1.1 0.7 0.8 1.5
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 2.2 1.0 0.8 0.6 0.9 0.7 0.3 0.7 0.4 0.8 0.9 1.3 -0.9 1.0 -0.5 0.8 -0.8 1.5 1.2 -0.0 0.6 0.2 1.1
Heart disease (siblings) 0.2 0.3 1.4 0.5 1.2 0.3 0.4 0.5 0.9 -0.8 0.1 0.2 0.5 -0.7 -0.6 -0.3 -0.7 0.5 -0.1 0.4 0.3 0.4 -0.0 0.2 0.6
Alcohol drinker status: Previous 0.5 0.6 1.7 0.8 0.2 0.7 1.1 0.9 -0.1 0.0 -0.2 0.6 0.8 -1.1 -0.7 1.3 -0.9 0.6 0.4 0.6 -0.4 0.1 1.0 1.1 0.9
Pack years of smoking 0.8 1.2 2.9 1.2 -0.2 1.2 1.3 1.4 -0.6 1.1 0.0 1.3 1.1 0.3 -0.9 0.9 1.1 1.1 1.3 1.2 1.6 0.6 1.3 1.7 1.2
Impedance of whole body 0.3 1.4 9.6 -1.0 0.0 -0.9 -0.8 -0.8 -1.8 0.4 0.5 -0.8 -1.0 -3.1 0.7 -1.8 1.0 -0.9 -0.7 -0.6 0.1 1.0 -1.3 -1.5 -1.0
Leg fat mass (left) 3.3 13.0 21.7 4.6 3.4 3.9 4.5 4.6 0.2 3.0 2.7 4.7 4.7 0.2 -4.3 3.9 1.4 4.5 0.1 4.5 2.9 2.0 3.7 3.8 4.6
Arm predicted mass (left) 1.9 9.6 17.4 4.1 2.5 3.6 3.9 3.8 0.8 2.4 1.7 3.8 4.1 1.5 -3.8 3.1 -0.2 4.1 0.3 3.7 2.5 0.2 3.5 3.5 4.2