Hub : Genes

RGCC

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.2240 0.0580 1.1e-07 0.172 NA 0.150 NA 0.162 5.6e-14 NA 2.8e-12 NA 3.1e-13
2 GTEx Adipose Visceral Omentum 0.2020 0.0740 2.1e-03 0.096 NA 0.056 NA 0.057 1.1e-05 NA 7.1e-04 NA 6.3e-04
3 GTEx Adrenal Gland 0.2111 0.0835 8.7e-03 0.000 NA 0.016 NA 0.019 3.2e-01 NA 8.5e-02 NA 6.7e-02
4 GTEx Colon Sigmoid 0.2070 0.0850 6.6e-03 -0.008 NA 0.020 NA 0.001 9.8e-01 NA 6.5e-02 NA 3.0e-01
5 GTEx Muscle Skeletal 0.0806 0.0277 6.8e-04 0.089 NA 0.060 NA 0.073 4.7e-09 NA 1.5e-06 NA 1.1e-07
6 GTEx Nerve Tibial 0.1203 0.0379 2.1e-04 0.100 NA 0.051 NA 0.080 1.6e-07 NA 1.6e-04 NA 2.5e-06
7 GTEx Skin Sun Exposed Lower leg 0.0840 0.0320 1.4e-03 0.005 NA 0.030 NA 0.022 1.1e-01 NA 1.5e-03 NA 5.8e-03
8 METSIM Adipose 0.1490 0.0325 0.0e+00 0.201 0.144 0.188 0.192 0.200 2.2e-29 7.4e-21 2.0e-27 5.3e-28 3.0e-29

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 2.2 3.5 7.7 2.4 2.8 -0.4 -0.4 1.7 2.0 0.5 2.6
Bipolar Disorder or Schizophrenia 0.6 1.5 2.7 1.5 1.7 -0.4 -0.7 1.4 1.5 0.4 1.4
Depressed Affect (Nagel 2018) 1.4 2.9 5.0 -2.1 -1.8 -2.1 -0.9 -1.1 -1.2 -1.7 -2.2
Depression (Nagel 2018) 0.3 0.5 0.6 -0.8 -0.6 -0.7 0.8 -0.7 -0.7 -0.3 -0.7
Intelligence (Savage-Jansen 2018) 1.9 5.7 9.4 2.2 1.7 3.0 2.4 2.3 2.1 3.1 2.0
Neuroticism (Nagel 2018) 1.1 2.6 5.7 -2.2 -2.0 -1.5 0.0 -0.5 -0.7 -1.6 -2.4
Schizophrenia (2018) 0.0 0.1 0.4 0.0 -0.1 -0.3 -0.6 0.3 0.3 0.2 -0.3
Schizophrenia vs Biploar Disorder 0.2 0.2 0.6 0.5 -0.1 0.7 0.8 -0.3 -0.1 0.6 0.4
Worry (Nagel 2018) 1.4 3.0 7.5 -2.5 -2.5 -0.3 0.0 -0.9 -1.2 -1.3 -2.7
Alzheimer’s Disease (in mother) 0.5 0.5 2.2 -0.8 -0.7 -0.5 -1.5 0.1 -0.2 -0.2 -0.9
Alzheimer’s Disease (in father) 0.3 0.4 0.8 -0.7 -0.5 0.3 0.3 0.8 0.4 0.7 -0.9
Alzheimer’s Disease (including proxy) 0.4 0.5 1.3 -1.0 -0.8 0.1 -0.5 0.7 0.3 0.7 -1.1
Crohns Disease (2017) 0.4 0.8 3.5 -0.1 0.6 -0.7 -0.1 0.9 1.0 -1.9 0.1
Irritable Bowel Disease (IBD) 0.2 0.4 1.8 -0.5 -0.1 0.2 0.6 0.6 0.5 -1.4 -0.3
Ulcerative Colitis (UC) 0.3 0.5 1.6 -0.2 -0.1 1.2 1.3 0.8 0.6 -0.0 -0.2
Major Depression (MDD) 1.7 2.0 11.3 0.7 0.9 0.7 3.4 1.1 0.8 0.7 0.9
Reaction Time 0.7 1.3 2.8 1.4 1.0 -1.1 0.5 1.1 0.9 1.7 1.1
Verbal and Numeric Reasoning (VNR) 0.9 2.2 4.9 1.2 1.0 1.8 1.8 1.2 1.2 2.2 1.1
Breast Cancer 0.3 0.8 2.4 0.8 0.5 -0.8 0.5 1.6 1.4 0.1 0.6
Ovarian Cancer 0.3 0.4 2.1 0.7 0.0 -1.5 -0.2 -0.3 -0.2 0.2 0.6
Prostate Cancer 1.3 1.9 3.8 1.5 2.0 -0.8 0.3 1.6 1.8 0.4 1.5
Age at First Birth 0.2 0.3 1.7 0.6 -0.2 0.6 0.3 0.1 -0.1 1.3 0.4
Bipolar Disorder (2011) 2.2 2.1 3.8 1.9 1.9 0.8 0.4 1.1 1.4 1.4 1.9
Body Mass Index (BMI) (2010) 1.1 1.5 2.7 -1.6 -1.3 -1.2 -1.0 -0.1 -0.4 -1.6 -1.6
Coronary Artery Disease (CAD) 0.6 0.8 1.8 1.2 0.8 -0.6 -0.6 -0.0 0.3 1.3 1.2
Crohns Disease (2012) 0.6 0.9 1.6 0.8 1.2 0.9 1.2 1.0 1.3 -0.3 0.8
Mean Putamen Volume 1.2 1.4 2.5 -1.3 -1.6 -0.9 -0.2 -1.4 -1.4 -0.2 -1.5
Fasting Glucose 0.2 0.2 0.6 -0.2 -0.3 0.5 0.6 -0.1 -0.2 0.8 -0.1
HbA1C 0.4 0.4 1.5 -0.4 -0.5 -0.4 -1.2 -0.1 -0.0 -1.0 -0.6
HDL Cholesterol 1.7 2.8 7.0 -1.3 -1.1 -0.6 -2.7 -1.9 -1.6 -2.1 -1.2
LDL Cholesterol 1.8 2.9 5.4 -2.3 -1.7 -0.8 -0.5 -1.9 -1.8 -1.5 -2.1
Lupus 2.4 3.6 5.6 2.4 1.8 0.8 -0.3 2.3 2.4 2.1 2.1
Neuroticism (2016) 2.6 3.8 7.4 -2.7 -2.4 -0.3 -0.3 -1.3 -1.5 -2.3 -2.7
Primary Biliary Cirrhosis 0.7 1.0 4.1 0.1 0.7 -2.0 -1.3 0.7 0.7 -0.8 0.1
Rheumatoid Arthritis 0.5 0.7 1.5 0.7 1.0 -1.1 -0.1 1.1 1.2 0.4 0.4
Schizophrenia (2014) 0.1 0.3 0.5 0.7 0.4 0.3 -0.6 0.7 0.6 0.1 0.6
Triglycerides 0.4 0.6 1.6 -1.0 -1.0 -0.3 1.3 -0.3 -0.5 0.1 -0.9
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.7 0.4 0.7 -1.3 0.5 0.5 0.7 0.9 0.3
Ulcerative Colitis 0.6 0.9 4.0 0.6 0.4 2.0 1.1 0.8 0.7 0.5 0.6
Blood Eosinophil Count 0.1 0.6 3.1 -0.0 0.2 1.8 1.0 -0.3 -0.3 0.8 -0.1
Blood Platelet Count 0.1 1.4 3.1 -1.3 -1.5 -0.6 -0.4 -1.5 -1.8 -0.2 -1.1
Blood Red Count 0.0 0.2 0.8 0.3 0.1 -0.9 -0.2 -0.6 -0.2 0.1 0.3
Blood White Count 0.5 3.8 8.8 -2.2 -1.9 -0.9 -1.6 -1.5 -1.8 -3.0 -2.0
Heel T-Score 3.9 31.2 55.7 4.6 4.8 7.5 7.4 4.4 4.7 5.7 4.5
BMI 0.2 1.3 2.6 -1.5 -1.3 -0.3 -0.9 -0.7 -0.7 -1.5 -1.6
Height 0.0 0.7 1.8 -0.1 -0.1 -0.6 1.4 1.2 0.8 -1.3 0.1
Waist Hip Ratio (WHR) 0.4 1.9 5.6 -2.1 -1.2 -1.5 -0.7 0.6 0.1 -0.1 -2.4
Systolic Blood Pressure 0.1 0.7 2.4 -0.2 -0.3 -0.7 -1.6 -1.2 -0.8 -0.8 -0.1
Smoking Status 0.2 0.4 1.3 0.7 0.6 0.2 1.2 0.5 0.6 -0.0 0.7
Allergy or Eczema 0.3 0.7 3.2 -0.3 -0.6 -1.8 -0.5 -1.0 -0.9 -0.0 -0.3
Cardiovascular Disease 0.4 1.2 2.4 -1.2 -0.9 0.6 -1.6 -0.5 -0.7 -1.3 -1.3
Hypothyroidism (self reported) 1.3 2.9 5.0 2.1 2.0 0.3 0.3 2.0 2.2 1.8 1.7
Respiratory disease 0.7 1.6 2.7 -1.1 -1.4 -1.6 1.0 -0.9 -1.0 -1.6 -1.3
Type 2 Diabetes (T2D) (2018) 0.2 0.5 2.1 0.4 0.5 1.4 0.1 -0.4 -0.2 0.9 0.4
Lung FEV1/FVC ratio 0.8 4.3 8.1 1.8 2.2 1.8 0.4 2.8 2.9 2.0 1.7
Lung FVC 0.7 3.5 7.7 2.7 2.0 0.3 0.1 0.5 0.9 2.7 2.8
Neuroticism 2.5 6.0 13.4 -3.4 -3.3 -1.2 -0.1 -1.7 -2.1 -1.8 -3.7
Chronotype (morning person) 2.7 6.3 10.0 -3.2 -2.7 -0.8 -1.9 -2.4 -2.4 -2.8 -3.1
Hair Pigment 0.0 1.0 2.5 1.3 1.2 -0.2 0.2 1.0 1.0 0.2 1.6
Tanning 0.5 5.9 9.8 -3.0 -2.8 0.3 -0.7 -2.3 -2.5 -3.1 -3.0
Hand grip strength (left) 0.1 0.2 0.6 -0.4 -0.5 -0.7 0.2 -0.1 -0.1 -0.8 -0.6
Number of treatments/medications taken 0.9 1.6 3.7 0.7 1.2 1.1 1.5 1.9 1.7 0.4 0.6
Average weekly spirits intake 0.1 0.2 0.9 0.0 0.4 0.9 0.5 0.2 0.2 0.2 0.1
Sensitivity / hurt feelings 0.6 1.1 1.9 -1.1 -1.0 -1.3 1.4 0.1 -0.2 -1.1 -1.2
Frequency of depressed mood in last 2 weeks 1.1 1.5 2.8 -1.7 -1.6 0.5 0.3 -0.9 -1.1 -1.5 -1.6
Hearing difficulty/problems: Yes 1.2 1.8 3.2 1.3 1.6 0.6 0.9 1.8 1.7 1.4 1.2
Relative age of first facial hair 0.8 1.7 3.5 -1.9 -1.3 -1.0 1.2 0.4 -0.2 -1.6 -1.8
Other serious medical condition/disability diagnosed by doctor 1.8 2.4 5.3 -2.2 -1.6 1.0 -1.3 0.1 -0.3 -1.9 -2.3
Ever used hormone-replacement therapy (HRT) 2.1 2.7 4.1 1.9 2.0 0.1 0.7 1.7 2.0 1.9 1.7
Ever had hysterectomy (womb removed) 1.4 1.5 3.6 -1.5 -1.1 -1.9 -0.3 -1.0 -1.0 -0.9 -1.5
Systolic blood pressure, automated reading 0.1 0.4 2.8 0.1 0.4 0.3 -1.7 -0.5 0.1 0.4 -0.0
Eye problems/disorders: Diabetes related eye disease 3.8 4.2 9.4 2.8 2.2 1.1 0.8 1.1 1.3 2.5 3.1
Angina 0.1 0.2 0.9 0.0 -0.2 0.3 0.5 0.1 -0.0 0.9 -0.1
Medication for hormone replacement therapy 0.2 0.2 1.6 -0.1 -0.5 0.0 -1.2 -0.3 -0.3 -0.0 -0.0
Vitamin and mineral supplements 0.6 0.8 5.3 0.1 -0.5 -0.8 -0.3 -0.4 -0.6 -2.3 0.4
Supplements: Zinc 1.4 1.5 5.1 1.5 1.1 0.4 0.6 0.5 0.6 2.3 1.5
Medication: Co-codamol 0.6 0.7 2.0 -1.0 -1.4 -0.0 -0.6 -0.7 -0.9 -0.2 -0.9
Medication: Metformin 0.2 0.3 1.1 -0.1 0.3 0.6 0.5 -0.5 -0.4 1.0 -0.1
Diabetes (father) 0.7 0.8 3.8 -0.2 -0.8 1.9 0.4 -0.7 -0.8 0.9 -0.2
Diabetes (mother) 0.3 0.4 1.0 -0.6 -1.0 1.0 0.5 -0.4 -0.6 0.2 -0.5
Severe depression (siblings) 0.4 0.5 2.4 0.1 0.7 1.5 -0.8 -0.4 -0.2 0.1 0.4
Pack years adult smoking proportion 0.6 0.9 2.7 0.3 0.5 0.3 1.1 1.6 1.5 -0.9 0.2
Impedance of leg (right) 0.1 0.5 1.1 0.8 0.2 -0.9 -1.1 -0.5 -0.3 0.6 1.0
Leg fat-free mass (left) 0.1 0.6 1.9 0.3 0.4 -0.1 1.0 1.4 1.2 -0.2 0.0
Trunk fat percentage 0.2 0.6 4.2 0.4 0.4 -0.4 -2.1 0.3 0.5 -0.0 0.2
Hand grip strength (right) 0.1 0.3 1.3 0.6 0.5 -0.5 1.2 -0.1 0.1 0.2 0.7
Townsend deprivation index at recruitment 0.3 0.5 1.5 -0.0 0.2 -1.2 -0.5 0.9 0.6 -0.8 0.3
Current tobacco smoking 0.5 0.9 1.5 1.0 1.2 -0.6 1.2 0.5 0.8 -0.5 1.1
Average weekly fortified wine intake 0.4 0.4 1.3 0.3 0.6 1.1 0.8 -0.6 -0.4 0.2 0.5
Maternal smoking around birth 0.2 0.3 1.8 0.2 0.0 1.4 -0.4 -0.4 -0.3 -0.2 0.2
Fed-up feelings 2.8 5.0 8.8 -2.7 -2.4 -2.5 -1.5 -0.9 -1.2 -2.8 -3.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.2 0.8 -0.2 -0.3 -0.9 0.7 -0.1 -0.2 -0.7 -0.2
Relative age voice broke 1.1 1.7 4.4 -2.1 -1.3 -0.2 0.3 0.1 -0.4 -1.7 -2.0
Taking other prescription medications 0.4 0.7 1.9 0.1 0.3 1.4 0.5 1.2 1.0 0.6 -0.1
Age when periods started (menarche) 0.1 0.2 0.6 0.4 0.4 -0.3 -0.2 0.8 0.6 -0.6 0.2
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 6.9 0.2 0.3 -2.6 -1.4 0.2 0.4 -0.4 0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 2.2 1.5 1.2 0.8 0.7 0.8 1.0 0.5 1.3
Tinnitus: Yes, but not now, but have in the past 0.8 0.8 1.7 -1.3 -1.2 -0.3 0.9 -0.4 -0.9 -0.0 -1.3
Qualifications: CSEs or equivalent 1.0 1.3 2.6 -0.7 -1.0 -0.8 -1.4 -1.3 -1.1 -1.6 -0.6
Serious illness, injury or assault to yourself 0.1 0.1 0.5 0.1 -0.2 0.7 -0.4 0.2 -0.0 -0.2 0.1
High blood pressure 0.3 0.7 4.2 0.4 0.7 2.1 -0.2 0.2 0.2 0.6 0.6
Hayfever, allergic rhinitis or eczema 0.6 1.2 3.3 -0.4 -1.2 -1.8 -0.4 -1.4 -1.5 -0.6 -0.4
Multivitamins +/- minerals 1.2 1.5 5.7 -0.0 0.3 2.0 1.3 0.5 0.6 2.4 -0.3
Stomach or abdominal pain in last month 1.0 1.2 2.8 -1.5 -1.7 0.2 0.3 -0.7 -1.1 -1.2 -1.2
Supplements: Glucosamine 1.2 1.6 3.2 0.0 0.6 1.4 1.6 1.8 1.7 1.2 -0.3
Diverticular disease/diverticulitis (self-reported) 4.4 5.2 9.9 -2.1 -2.9 1.4 -1.8 -2.9 -3.1 -1.5 -1.8
Medication: Atenolol 0.7 0.9 3.6 0.1 0.4 1.9 1.5 0.5 0.5 0.6 0.0
Medication: Levothyroxine sodium 1.6 2.8 5.9 2.0 2.2 0.1 -0.6 2.0 2.4 1.0 1.6
Sitting height 0.4 2.6 5.4 1.9 1.5 -0.7 2.3 1.5 1.5 1.0 1.9
Chronic bronchitis/emphysema (father) 0.5 0.6 2.1 0.2 -0.3 0.7 -0.5 -1.5 -1.1 0.6 0.2
High blood pressure (mother) 0.7 1.0 2.4 -1.1 -1.5 0.1 0.1 -0.8 -0.9 -1.0 -1.4
Body mass index (BMI) 0.1 0.6 1.8 -0.7 -0.6 -0.4 -1.4 -0.6 -0.4 -0.8 -0.9
Impedance of leg (left) 0.1 0.7 1.3 0.7 0.1 -0.9 -1.1 -1.0 -0.8 0.5 1.0
Leg predicted mass (left) 0.1 0.5 1.6 0.2 0.4 -0.2 0.9 1.3 1.1 -0.2 -0.0
Trunk fat mass 0.1 0.4 1.7 0.4 0.5 -0.2 -1.3 0.5 0.7 0.0 0.3
Waist circumference 0.1 0.3 1.5 -0.4 -0.1 -0.6 -1.2 0.3 0.4 -0.1 -0.6
Number of incorrect matches in round 0.4 0.6 2.4 0.2 -0.4 0.5 -1.5 -1.0 -0.9 -0.3 0.4
Past tobacco smoking 0.5 0.9 3.8 -0.2 -0.2 -0.9 -1.9 -1.1 -0.6 -0.8 -0.2
Alcohol usually taken with meals 0.9 1.5 4.5 1.1 1.1 0.6 2.1 1.3 1.3 0.6 0.9
Nervous feelings 1.7 3.1 4.9 -2.0 -2.2 0.5 -1.8 -1.5 -1.5 -1.8 -2.2
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 2.5 -1.4 -1.2 -0.8 -0.6 -0.4 -0.6 -1.6 -1.5
Hearing difficulty/problems with background noise 0.4 0.6 1.7 0.7 1.3 -0.4 -0.4 0.8 1.0 -0.4 0.8
Hair/balding pattern: Pattern 2 1.3 1.6 4.0 -0.9 -1.0 -1.1 -2.0 -1.4 -1.2 -1.3 -0.8
Had menopause 1.9 2.3 3.9 1.9 1.8 1.5 -0.7 0.8 1.2 1.8 2.0
Had other major operations 0.9 1.1 2.3 -1.5 -1.3 -1.1 -0.2 0.0 -0.4 -1.2 -1.4
Forced vital capacity (FVC) 0.1 0.5 1.4 0.9 0.6 0.3 0.6 0.3 0.2 0.8 1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.0 0.9 1.0 0.5 0.7 0.7 0.8 0.0 0.7
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.2 0.4 -0.4 0.1 -0.8 -1.1 -1.0 -0.4 0.6
Qualifications: None of the above 1.9 4.1 6.7 -2.0 -2.0 -1.6 -2.6 -1.7 -1.6 -2.5 -1.9
Financial difficulties in last 2 years 0.1 0.1 0.5 -0.5 -0.1 -0.1 -0.3 -0.3 -0.3 -0.7 -0.3
Mouth/teeth dental problems 0.2 0.3 1.6 0.5 0.3 -0.4 1.3 -0.3 -0.1 0.2 0.4
Heart attack 0.5 0.6 2.3 0.7 0.3 0.1 1.5 0.6 0.5 -0.8 0.8
Allergy 0.7 1.7 3.2 0.9 1.7 1.8 -0.0 1.4 1.6 1.0 0.9
Pain all over the body in last month 0.3 0.4 1.8 0.2 0.1 -1.3 0.2 0.3 0.4 -0.8 -0.2
Diabetes (self-reported) 0.2 0.3 1.2 0.3 0.4 1.1 0.6 -0.5 -0.4 0.4 0.4
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.2 -1.5 -1.5 -1.0 0.5 0.9 0.1 -0.5 -1.8
Medication: Ramipril 0.8 1.1 5.9 -0.4 -0.5 2.4 -0.3 -1.0 -0.9 -0.4 -0.3
Medication: Simvastatin 0.2 0.3 0.6 -0.8 -0.4 0.6 0.7 0.2 0.0 -0.1 -0.8
Fluid intelligence score 1.0 2.0 5.0 1.0 0.9 1.9 1.0 1.4 1.4 2.2 0.9
Illnesses of siblings 0.6 0.8 2.9 -0.5 -0.6 -1.0 -1.0 -0.5 -0.5 -1.7 -0.4
Neuroticism score 3.5 7.3 13.8 -3.6 -3.6 -1.2 -1.0 -1.6 -2.2 -3.0 -3.7
Weight 0.0 0.1 0.4 0.1 0.2 -0.1 -0.1 0.6 0.6 -0.2 -0.0
Impedance of arm (right) 0.1 0.4 2.7 0.2 -0.2 -0.2 -1.7 0.3 0.0 0.0 0.3
Arm fat percentage (right) 0.2 0.8 4.3 -0.7 -0.6 -0.4 -2.1 -0.4 -0.3 -0.6 -0.8
Trunk fat-free mass 0.2 1.0 5.8 0.2 0.5 -0.1 2.4 1.1 1.0 0.5 0.0
Hip circumference 0.0 0.1 0.6 0.2 0.0 -0.4 -0.7 0.1 0.2 -0.2 0.1
Time employed in main current job 0.7 0.8 1.7 -1.0 -1.3 0.4 0.4 -0.5 -0.9 -1.1 -1.0
Alcohol intake versus 10 years previously 0.9 1.3 2.7 -1.6 -1.0 -1.6 0.7 -0.7 -0.6 -0.7 -1.6
Father’s age at death 3.3 4.4 7.7 2.4 2.8 1.5 1.5 1.7 2.1 2.0 2.4
Worrier / anxious feelings 2.5 4.7 11.6 -3.1 -3.0 -0.1 -0.4 -1.2 -1.6 -1.6 -3.4
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.7 -0.3 -0.8 0.9 0.2 -0.2 -0.3 -0.4 -0.5
Falls in the last year 0.7 1.0 2.3 -1.0 -1.4 -0.2 -1.5 -0.5 -0.9 -0.8 -0.9
Hair/balding pattern: Pattern 3 0.5 0.8 3.9 -0.1 -0.4 2.0 1.3 0.5 0.1 -0.2 -0.1
Number of live births 0.9 1.3 2.5 -0.8 -1.1 -0.6 -1.2 -1.6 -1.5 -1.2 -0.9
Forced expiratory volume in 1-second (FEV1) 0.1 0.2 0.7 0.6 0.5 0.3 0.2 0.4 0.3 0.5 0.8
Pulse rate 0.3 0.5 1.2 0.5 0.4 0.2 -0.9 1.1 1.1 -0.6 0.4
Happiness 0.3 0.4 1.7 0.0 -0.0 1.3 0.9 -0.1 -0.0 -0.7 0.1
Noisy workplace 0.1 0.1 0.2 0.1 0.3 -0.4 0.5 -0.4 -0.3 -0.2 0.3
Qualifications: A levels/AS levels or equivalent 2.1 4.6 7.6 2.5 2.1 1.2 1.4 2.3 2.1 2.7 2.5
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.6 -0.3 0.1 -0.0 0.8 -0.2 -0.3 0.3 -0.1
Mouth/teeth dental problems: Dentures 0.6 1.0 5.0 -0.6 -0.1 2.2 0.2 1.0 0.8 0.2 -0.9
Asthma 1.0 2.0 4.5 -1.0 -1.7 -1.1 -0.4 -2.1 -2.1 -1.3 -0.9
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.6 1.4 0.6 0.7 -0.6 0.8 0.7 0.7 1.2 0.5
Medication: Cholesterol lowering 0.6 0.9 3.3 0.5 0.9 0.5 1.2 0.8 0.8 1.8 0.3
Depression (self-reported) 1.0 1.2 4.6 -0.1 -0.5 -1.1 -2.1 -1.0 -0.8 -1.3 -0.1
Medication: Lansoprazole 0.2 0.2 0.9 -0.1 0.1 0.4 0.3 0.3 0.3 -1.0 -0.2
Prospective memory result 3.3 4.1 7.6 -2.8 -2.5 -0.6 0.7 -1.9 -2.2 -1.2 -2.7
Lung cancer (father) 0.8 0.9 2.0 -0.9 -0.7 0.5 -0.8 -1.2 -1.0 -1.4 -0.7
Illnesses of mother 0.1 0.2 0.7 0.3 0.3 -0.8 0.5 -0.3 -0.2 0.3 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.8 2.2 1.2 1.0 -0.7 -0.3 0.8 0.8 0.2 1.5
Pulse wave Arterial Stiffness index 1.5 1.7 5.6 -1.0 -0.3 -1.9 0.0 1.3 0.8 -2.4 -0.9
Impedance of arm (left) 0.1 0.3 1.5 0.4 0.0 0.3 -1.2 0.6 0.3 0.1 0.5
Arm fat mass (right) 0.1 0.3 1.8 -0.3 -0.3 -0.2 -1.3 -0.0 0.0 -0.4 -0.5
Trunk predicted mass 0.2 0.9 5.6 0.0 0.3 -0.0 2.4 0.9 0.8 0.4 -0.1
Standing height 0.3 2.7 6.9 1.4 1.4 0.2 2.6 2.1 1.8 1.0 1.5
Length of working week for main job 0.5 0.5 1.0 -0.8 -0.8 0.6 -0.9 -0.3 -0.3 -1.0 -0.7
Exposure to tobacco smoke at home 0.7 0.7 3.0 0.7 0.6 -1.7 -1.0 -0.2 -0.0 0.7 0.8
Breastfed as a baby 0.5 0.6 1.8 -0.9 -1.4 0.4 -0.4 -0.3 -0.6 0.3 -1.1
Tense / ‘highly strung’ 1.1 1.8 7.2 -1.4 -1.7 0.0 -0.4 -0.2 -0.7 -2.7 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 2.9 4.4 7.9 -2.5 -2.8 -0.9 0.2 -2.2 -2.5 -2.0 -2.3
Hair/balding pattern: Pattern 4 3.1 7.6 19.4 3.1 3.2 1.3 1.2 2.0 2.4 4.4 2.9
Birth weight of first child 0.3 0.5 2.0 0.1 0.1 -0.9 -1.4 -0.5 -0.4 -0.7 0.3
Peak expiratory flow (PEF) 0.1 0.3 1.0 0.6 0.3 1.0 -0.0 -0.0 0.1 -0.0 0.8
Pulse wave reflection index 1.4 1.7 3.1 -1.3 -1.1 -1.6 -1.2 -0.9 -1.3 -1.8 -1.0
Ever highly irritable/argumentative for 2 days 0.9 1.1 1.8 -1.1 -0.5 -1.4 -0.9 -0.9 -1.0 -1.3 -0.8
Loud music exposure frequency 1.1 1.2 2.7 1.3 1.6 0.7 0.3 0.5 0.8 1.5 1.3
Qualifications: O levels/GCSEs or equivalent 1.0 1.7 5.5 1.3 0.7 0.2 1.3 1.2 1.0 2.4 1.2
Mouth/teeth dental problems: Bleeding gums 0.1 0.2 0.6 -0.4 -0.6 0.2 -0.7 -0.1 -0.4 0.2 -0.4
Blood clot in the leg (DVT) 0.3 0.4 0.8 -0.8 -0.6 -0.3 -0.5 0.3 0.0 0.8 -0.9
Medication: Paracetamol 0.8 1.4 3.1 -0.9 -1.6 -1.8 -0.5 -1.1 -1.3 0.4 -1.1
Headache pain in last month 0.5 0.9 1.8 0.7 0.7 -1.3 1.3 0.7 0.7 1.2 0.6
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.5 0.3 -0.0 -0.3 -0.7 0.1 0.1 -0.7 0.4
Glaucoma (self-reported) 0.5 0.6 1.5 -0.4 -0.2 0.5 1.2 1.2 0.9 0.0 -0.6
Gout (self-reported) 1.1 1.5 3.3 -1.4 -1.2 -0.9 -1.4 -0.8 -0.8 -0.9 -1.8
Hypothyroidism/myxoedema (self-reported) 1.5 3.0 5.1 2.1 1.8 0.9 0.6 2.1 2.3 1.6 1.8
Medication: Amlodipine 0.2 0.3 0.7 0.7 0.6 0.5 -0.5 0.1 0.3 0.2 0.8
Medication: Ventolin 100micrograms inhaler 1.0 1.2 3.0 1.0 1.3 0.2 0.9 1.7 1.7 0.3 0.8
Birth weight 0.2 0.5 0.9 -0.5 -0.6 -0.9 0.9 0.6 0.4 -0.8 -0.7
Chronic bronchitis/emphysema (mother) 1.7 2.0 2.6 -1.4 -1.4 1.5 -1.5 -1.4 -1.6 -1.5 -1.0
High blood pressure (siblings) 0.3 0.4 1.1 -0.3 -0.4 0.6 1.1 -0.2 -0.2 1.0 -0.3
Forced vital capacity (FVC), Best measure 0.3 0.9 2.4 1.4 1.1 -0.8 -0.0 0.8 0.8 0.2 1.6
Body fat percentage 0.1 0.6 3.6 0.4 0.5 -0.4 -1.9 0.2 0.4 0.1 0.3
Leg fat percentage (right) 0.1 0.5 3.3 -0.0 0.0 -0.7 -1.8 -0.5 -0.2 -0.2 -0.2
Arm fat-free mass (right) 0.1 0.6 2.4 0.3 0.6 0.0 1.5 0.9 1.0 0.3 0.2
Exposure to tobacco smoke outside home 0.8 1.0 7.1 -0.5 -0.6 -2.7 0.4 -0.0 -0.2 0.1 -0.6
Comparative body size at age 10 0.7 1.9 4.0 -1.7 -1.6 -0.2 0.3 -1.7 -2.0 -0.1 -1.6
Number of full brothers 0.7 0.8 1.3 1.2 1.1 -0.0 1.0 0.9 0.9 -0.0 1.2
Worry too long after embarrassment 0.2 0.4 1.1 0.1 0.1 -0.0 1.1 0.8 0.8 -0.8 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.8 2.3 4.0 -2.0 -1.8 -0.9 -1.0 -0.8 -1.1 -1.9 -1.9
Wheeze or whistling in the chest in last year 0.9 1.7 3.3 1.0 0.5 -0.7 1.8 1.8 1.7 1.6 0.3
Number of children fathered 0.8 0.9 2.1 -0.9 -1.2 1.4 -0.7 -0.5 -0.6 -0.6 -1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.8 1.0 2.6 -1.4 -1.0 -0.6 -0.9 0.4 0.1 -0.9 -1.6
Age at first live birth 0.1 0.1 0.8 -0.0 0.3 -0.9 -0.2 0.1 0.2 0.1 -0.0
Pulse wave peak to peak time 1.6 1.9 6.2 1.3 0.5 2.1 0.3 -1.0 -0.5 2.5 1.2
Health satisfaction 0.6 0.8 3.2 0.6 0.0 1.8 1.3 -0.1 -0.1 0.7 0.6
Shortness of breath walking on level ground 1.0 1.2 5.1 0.8 0.8 0.7 2.3 0.7 0.6 0.7 0.9
Qualifications: College or University degree 0.7 2.2 4.4 1.3 1.2 2.1 1.6 1.4 1.0 1.6 1.5
Eye problems/disorders: None of the above 1.5 1.7 2.8 -1.1 -1.0 -0.6 -1.6 -1.5 -1.6 -1.7 -0.9
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.7 0.0 0.0 0.6 0.4 0.6 0.4 -0.8 0.1
Emphysema/chronic bronchitis 1.3 1.5 4.6 1.2 1.0 -0.3 2.1 1.2 1.4 0.7 1.1
Medication for pain relief, constipation, heartburn 0.6 1.0 3.0 1.5 1.4 0.4 0.1 -0.3 0.3 0.2 1.7
Neck or shoulder pain in last month 1.1 1.5 3.3 -1.5 -1.8 -0.5 -0.3 -1.2 -1.7 -0.7 -1.2
Medication: Blood pressure 0.2 0.3 1.4 -0.2 -0.1 0.8 1.2 0.3 0.1 0.6 -0.3
Angina (self-reported) 0.1 0.1 0.8 -0.0 -0.1 0.3 0.2 0.0 -0.1 0.9 -0.2
Migraine (self-reported) 4.8 5.9 10.4 2.7 3.2 0.7 2.7 1.9 2.2 2.2 2.9
Medication: Ibuprofen 0.1 0.2 1.0 0.0 0.0 -1.0 -0.1 -0.1 -0.1 0.4 -0.1
Medication: Allopurinol 1.0 1.3 4.4 -1.7 -1.1 -0.5 -1.1 -0.1 -0.2 -0.5 -2.1
Medication: Omeprazole 0.8 0.9 2.5 -1.3 -1.5 -0.1 -0.9 -0.0 -0.3 -0.4 -1.6
Medication: Seretide 50 evohaler 1.6 1.8 4.9 0.7 1.2 -0.5 2.2 2.0 1.8 0.2 0.6
Mean time to correctly identify matches 1.3 2.5 5.0 1.7 1.7 -0.9 0.2 1.8 1.8 2.2 1.4
Heart disease (mother) 3.4 4.1 6.3 2.4 2.4 1.1 1.5 2.3 2.5 1.0 2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.7 3.2 7.2 2.6 2.3 1.4 -0.1 0.8 1.4 1.4 2.7
Whole body fat mass 0.1 0.3 1.5 0.3 0.4 -0.4 -1.2 0.3 0.5 -0.0 0.2
Leg fat mass (right) 0.1 0.2 1.3 0.2 0.3 -0.2 -1.2 0.0 0.2 -0.1 0.0
Arm predicted mass (right) 0.1 0.6 3.0 0.3 0.5 -0.1 1.7 0.8 0.9 0.3 0.2
Pulse rate, automated reading 0.2 0.7 2.3 0.3 0.7 -0.7 0.2 1.5 1.4 0.0 0.2
Alcohol intake frequency. 0.4 0.9 2.7 0.8 0.8 -0.0 1.6 0.4 0.7 1.3 0.9
Comparative height size at age 10 0.0 0.0 0.2 0.1 -0.1 -0.1 0.2 0.4 0.3 -0.2 -0.1
Number of full sisters 0.2 0.2 1.2 0.2 0.3 0.1 0.3 0.4 0.6 1.1 -0.0
Suffer from ‘nerves’ 2.1 3.3 5.6 -2.2 -2.4 -0.3 -1.7 -1.4 -1.5 -2.1 -2.2
Overall health rating 0.2 0.5 1.1 -0.6 -1.0 0.3 0.4 -0.7 -0.8 -0.6 -0.7
Chest pain or discomfort 1.7 2.4 5.6 2.0 1.6 0.9 1.0 1.1 1.3 2.4 1.7
Had major operations 0.3 0.4 0.9 0.7 0.8 0.6 0.9 -0.0 0.2 -0.2 0.9
Age at last live birth 0.5 0.7 1.6 -0.9 -0.3 -1.2 -0.6 -1.0 -0.7 -0.3 -1.0
Family relationship satisfaction 0.9 1.1 5.0 -0.7 -0.4 -0.4 -0.3 -1.3 -1.2 -2.2 -0.3
Leg pain on walking 0.2 0.2 0.9 0.1 -0.6 0.9 0.6 0.2 -0.1 0.4 -0.0
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 2.9 1.7 1.4 -0.6 -0.2 0.3 0.6 0.9 1.7
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.4 0.6 -0.1 -0.0 -0.6 -0.2 0.0 -0.1 0.4
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 5.3 -0.7 -1.1 -1.6 -2.3 -1.0 -0.9 -0.6 -1.0
Medication: Aspirin 0.4 0.5 2.7 -0.1 -0.1 1.6 -0.2 0.7 0.4 0.4 -0.4
Supplements: Vitamin C 0.6 0.7 2.1 -0.7 0.0 -1.3 -1.5 -1.0 -0.7 0.0 -0.5
Knee pain experienced in last month 0.2 0.3 1.1 0.0 -0.2 0.9 0.7 -0.2 -0.3 1.0 0.0
Hypertension (Self-reported) 0.1 0.4 2.5 -0.3 0.1 1.6 -0.5 -0.1 -0.2 0.1 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 1.4 -0.9 -1.0 -0.9 -0.1 -0.5 -0.5 -1.2 -1.1
Illnesses of father: Heart disease 2.8 3.8 6.8 2.2 2.1 -0.0 1.1 2.2 2.3 2.6 1.9
Illnesses of siblings: Diabetes 2.7 3.3 5.3 2.1 2.2 -0.2 1.6 1.5 1.9 2.3 1.9
Smoking status: Previous 0.7 1.1 4.2 0.4 0.3 0.8 2.0 1.3 0.8 0.9 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 3.5 0.2 0.4 -1.9 -0.4 -0.2 -0.0 -1.5 0.3
Whole body fat-free mass 0.1 0.7 3.2 0.2 0.4 0.0 1.8 1.1 1.0 0.2 0.0
Leg fat-free mass (right) 0.1 0.6 1.6 0.2 0.4 -0.1 1.2 1.2 1.1 -0.2 0.0
Arm fat percentage (left) 0.2 0.8 4.2 -0.6 -0.5 -0.1 -2.1 -0.4 -0.3 -0.7 -0.7
Average weekly red wine intake 0.3 0.4 0.8 -0.8 -0.7 0.5 -0.1 0.2 -0.1 -0.9 -0.9
Handedness (chirality/laterality): Left-handed 0.6 0.7 4.0 -0.5 -0.8 2.0 0.4 -0.0 -0.4 -0.4 -0.4
Mood swings 1.6 3.0 4.6 -2.1 -2.1 -1.2 -1.0 -1.4 -1.5 -1.9 -2.1
Loneliness, isolation 1.4 2.0 7.1 -1.6 -0.5 -0.7 0.6 1.2 0.8 -2.7 -1.8
Long-standing illness, disability or infirmity 0.2 0.3 0.8 -0.0 0.1 0.2 0.9 0.9 0.8 -0.2 -0.3
Ever had bowel cancer screening 1.1 1.3 9.9 -0.3 -0.1 3.1 0.0 -0.1 0.1 0.2 -0.1
Diabetes diagnosed by doctor 0.2 0.4 1.3 0.3 0.5 1.1 -0.0 -0.6 -0.4 0.8 0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.9 2.1 3.6 -1.1 -1.4 -1.3 -1.3 -1.9 -1.8 -1.6 -0.9
Friendships satisfaction 0.3 0.3 1.1 0.5 0.4 -1.1 0.1 -0.1 0.1 -0.7 0.8
Qualifications: nursing, teaching 1.3 2.1 3.6 0.8 1.3 1.2 1.8 1.9 1.7 1.7 0.6
Commuting to job workplace: Walk 2.2 2.4 3.9 -1.9 -1.5 -0.1 -2.0 -1.0 -1.3 -1.9 -1.7
Eye problems/disorders: Cataract 0.7 0.8 1.6 0.7 0.9 -0.7 0.6 1.1 1.3 1.0 0.3
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 2.0 1.2 1.4 0.2 -1.0 0.9 1.2 0.5 1.3
Medication for cholesterol 0.2 0.3 1.7 0.3 0.4 -1.3 0.4 -0.2 -0.0 -0.0 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.4 1.7 4.1 -1.9 -1.3 -0.0 0.2 -0.3 -0.7 -2.0 -1.8
Back pain experienced in last month 0.6 0.8 1.4 -0.9 -1.2 -1.1 -0.2 -1.0 -1.1 -0.4 -0.8
Mineral and other dietary supplements 4.6 6.2 8.8 -2.1 -2.4 -2.9 -2.1 -2.5 -2.8 -3.0 -1.9
Breast cancer (self-reported) 0.7 0.8 2.3 -1.3 -0.9 0.5 0.2 0.2 -0.2 -1.5 -1.3
Asthma (self-reported) 0.8 1.6 3.4 -0.9 -1.6 -0.8 0.0 -1.7 -1.8 -1.2 -0.9
Osteoporosis (self-reported) 0.5 0.6 2.3 -0.1 -0.4 -1.3 -1.5 -0.7 -0.5 -0.2 -0.2
Osteoarthritis (self-reported) 0.1 0.2 0.8 -0.1 -0.1 -0.3 0.9 0.4 0.4 0.2 -0.3
Medication: Aspirin 0.3 0.4 1.8 -0.6 -0.3 1.3 -0.5 0.3 0.1 0.1 -0.8
Medication: Gliclazide 0.2 0.2 0.8 0.1 0.2 -0.9 -0.6 -0.2 0.0 0.7 -0.1
Illnesses of father: None of the above (group 1) 3.2 4.0 9.0 -2.3 -1.9 -0.5 -1.8 -1.6 -1.7 -3.0 -2.2
Smoking status: Current 0.2 0.3 0.5 0.6 0.7 -0.6 0.7 -0.0 0.3 -0.6 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.7 0.3 0.3 0.2 0.8 0.7 0.4 0.4 0.5
Whole body water mass 0.1 0.7 2.9 0.2 0.5 -0.1 1.7 1.2 1.1 0.1 0.0
Leg predicted mass (right) 0.1 0.6 1.8 0.2 0.4 -0.0 1.2 1.3 1.2 -0.2 0.0
Arm fat mass (left) 0.1 0.3 1.7 -0.3 -0.3 -0.1 -1.3 -0.0 0.0 -0.5 -0.5
Number of self-reported non-cancer illnesses 0.2 0.3 2.2 -0.2 0.1 1.5 -0.1 0.3 0.3 0.1 -0.3
Average weekly champagne plus white wine intake 1.5 2.0 4.0 1.6 1.7 -0.1 1.2 1.8 2.0 1.0 1.1
Miserableness 1.8 3.2 6.1 -2.2 -2.5 -2.2 -0.3 -0.9 -1.5 -1.4 -2.2
Guilty feelings 1.1 1.7 3.8 -1.9 -1.6 -0.8 -0.9 -0.4 -0.8 -1.1 -1.9
Wears glasses or contact lenses 0.9 1.1 5.2 0.5 0.3 1.6 0.5 0.0 0.1 2.3 0.4
Ever taken oral contraceptive pill 2.2 2.5 4.3 2.1 2.1 -1.1 0.4 1.5 1.7 0.4 2.1
Hearing aid user 3.2 3.6 6.6 1.6 1.8 1.4 2.6 2.5 2.3 0.7 1.6
Mother’s age at death 0.2 0.2 0.9 0.4 0.6 -0.2 0.1 -0.3 0.1 1.0 0.3
Financial situation satisfaction 0.6 0.7 3.1 0.0 -0.5 -0.5 -1.1 -0.6 -0.7 -1.8 0.2
Tinnitus: Yes, now most or all of the time 0.7 0.8 1.7 0.9 1.0 -0.9 0.6 1.0 1.3 0.9 0.6
Commuting to job workplace: Public transport 0.8 0.9 2.0 0.8 1.2 1.4 0.2 0.9 1.0 1.1 0.7
Eye problems/disorders: Glaucoma 0.3 0.3 1.5 -0.4 -0.3 0.6 1.2 0.4 0.3 0.3 -0.5
Medication: Blood pressure 0.2 0.4 2.4 -0.4 -0.6 1.5 -0.1 -0.3 -0.5 0.0 -0.4
Pain type(s) experienced in last month: Hip pain 0.9 1.1 3.7 0.4 0.2 1.7 1.9 0.3 0.3 1.4 0.6
Supplements: Fish oil (including cod liver oil) 3.5 4.5 8.1 1.8 2.2 2.9 2.0 1.6 2.0 2.5 1.8
High cholesterol (Self-reported) 0.3 0.5 1.8 -1.2 -0.9 0.4 -0.2 0.3 -0.0 -0.2 -1.3
Medication: Bendroflumethiazide 1.5 2.3 4.1 1.9 1.6 1.8 0.8 0.6 0.8 1.9 2.0
Medication: Paracetamol 0.9 1.4 2.2 -1.1 -1.5 -1.2 -0.9 -1.3 -1.5 -0.0 -1.2
Medication: Lisinopril 0.3 0.4 1.8 -0.3 0.2 -0.4 0.4 1.3 1.0 -0.3 -0.4
Medication: Atorvastatin 0.9 1.2 3.5 1.4 1.1 0.1 -0.1 0.7 0.7 1.9 1.3
Illnesses of father: High blood pressure 1.1 1.4 2.9 0.9 1.0 -0.2 1.7 1.3 1.2 1.6 0.8
Alcohol drinker status: Never 0.8 0.9 3.3 0.5 0.2 1.2 1.2 -0.3 -0.4 1.8 0.8
Ever smoked 0.7 1.2 4.5 0.5 0.5 0.2 2.1 1.5 1.1 0.8 0.3
Basal metabolic rate 0.1 0.5 1.8 0.2 0.5 -0.3 1.3 1.1 1.0 0.1 0.0
Leg fat percentage (left) 0.1 0.5 2.8 0.1 0.2 -0.7 -1.7 -0.7 -0.3 -0.1 0.0
Arm fat-free mass (left) 0.1 0.6 2.6 0.5 0.6 -0.2 1.6 0.8 0.8 0.5 0.3
Number of operations (self-reported) 0.2 0.3 0.9 -0.8 -0.3 -0.0 0.2 0.1 0.0 -1.0 -0.7
Average weekly beer plus cider intake 0.5 0.8 1.3 0.8 1.2 -0.6 1.0 0.8 0.9 0.6 1.1
Irritability 1.1 1.9 3.9 -1.8 -1.9 -1.1 -0.3 -1.1 -1.3 -0.8 -2.0
Risk taking 0.2 0.3 1.5 -0.4 -0.1 -0.0 1.2 0.8 0.3 -0.3 -0.3
Ever had prostate specific antigen (PSA) test 0.7 0.8 3.0 0.2 0.6 1.7 0.3 0.8 0.7 1.3 0.0
Fractured/broken bones in last 5 years 0.2 0.2 0.6 0.4 -0.2 0.8 0.3 0.8 0.5 0.4 0.2
Age started oral contraceptive pill 2.8 3.6 12.1 1.7 1.9 0.9 -0.1 1.8 2.0 3.5 1.3
Diastolic blood pressure, automated reading 0.2 0.5 2.1 -0.2 -0.2 -0.7 -1.5 -0.7 -0.5 -0.5 -0.3
Ever depressed for a whole week 1.5 1.8 4.2 -1.6 -1.4 0.8 -0.7 -1.1 -1.3 -2.1 -1.3
Unable to work because of sickness or disability 1.3 1.6 2.8 -1.2 -1.5 0.2 -1.7 -1.4 -1.4 -1.4 -0.9
Commuting to job workplace: Cycle 2.4 2.9 6.3 -2.5 -1.9 -1.5 0.2 -0.7 -1.4 -1.5 -2.5
Myopia 0.6 0.9 1.9 0.8 0.3 0.5 -1.2 -1.4 -0.9 0.9 1.1
Vascular/heart problems diagnosed by doctor 0.3 0.9 4.7 -0.5 -0.8 -2.2 -0.2 -0.8 -0.7 -0.6 -0.6
Cholesterol lowering medication 0.7 1.0 3.3 -1.1 -1.0 1.8 0.6 0.6 0.2 -0.4 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.4 -0.9 -0.9 -0.6 -1.0 0.3 0.0 -0.2 -1.2
Pain experienced in last month 0.5 0.8 1.6 0.9 1.3 1.3 -0.9 0.5 0.9 0.3 0.9
Supplements: Calcium 0.4 0.5 2.7 0.2 0.6 0.1 -1.6 0.0 0.4 0.5 0.4
Basal cell carcinoma (self-reported) 0.5 0.6 1.7 -0.1 -0.2 0.5 -1.3 -1.2 -1.1 0.0 0.1
Heart attack/myocardial infarction (self-reported) 0.6 0.7 2.6 0.8 0.4 0.2 1.6 0.9 0.8 -0.4 0.9
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 2.2 -1.4 -1.3 -0.1 -0.8 -0.1 -0.4 0.4 -1.5
Heart disease (siblings) 2.9 3.6 6.2 1.9 2.2 2.5 1.5 1.2 1.5 2.3 1.8
Alcohol drinker status: Previous 2.9 3.3 4.8 1.8 2.0 0.8 1.9 1.9 2.2 1.9 1.8
Pack years of smoking 0.8 1.1 3.2 0.2 0.4 0.9 1.4 1.8 1.6 -0.5 0.1
Impedance of whole body 0.1 0.4 1.6 0.6 0.2 -0.4 -1.3 0.0 -0.0 0.2 0.8
Leg fat mass (left) 0.0 0.2 1.1 0.3 0.4 -0.2 -1.0 0.0 0.3 -0.0 0.1
Arm predicted mass (left) 0.1 0.5 2.0 0.3 0.5 -0.3 1.4 0.8 0.8 0.3 0.2