Hub : Genes

RGCC

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2240	0.0580	1.1e-07	0.172	NA	0.150	NA	0.162	5.6e-14	NA	2.8e-12	NA	3.1e-13
2	GTEx	Adipose Visceral Omentum	0.2020	0.0740	2.1e-03	0.096	NA	0.056	NA	0.057	1.1e-05	NA	7.1e-04	NA	6.3e-04
3	GTEx	Adrenal Gland	0.2111	0.0835	8.7e-03	0.000	NA	0.016	NA	0.019	3.2e-01	NA	8.5e-02	NA	6.7e-02
4	GTEx	Colon Sigmoid	0.2070	0.0850	6.6e-03	-0.008	NA	0.020	NA	0.001	9.8e-01	NA	6.5e-02	NA	3.0e-01
5	GTEx	Muscle Skeletal	0.0806	0.0277	6.8e-04	0.089	NA	0.060	NA	0.073	4.7e-09	NA	1.5e-06	NA	1.1e-07
6	GTEx	Nerve Tibial	0.1203	0.0379	2.1e-04	0.100	NA	0.051	NA	0.080	1.6e-07	NA	1.6e-04	NA	2.5e-06
7	GTEx	Skin Sun Exposed Lower leg	0.0840	0.0320	1.4e-03	0.005	NA	0.030	NA	0.022	1.1e-01	NA	1.5e-03	NA	5.8e-03
8	METSIM	Adipose	0.1490	0.0325	0.0e+00	0.201	0.144	0.188	0.192	0.200	2.2e-29	7.4e-21	2.0e-27	5.3e-28	3.0e-29

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	2.2	3.5	7.7	2.4	2.8	-0.4	-0.4	1.7	2.0	0.5	2.6
Bipolar Disorder or Schizophrenia	0.6	1.5	2.7	1.5	1.7	-0.4	-0.7	1.4	1.5	0.4	1.4
Depressed Affect (Nagel 2018)	1.4	2.9	5.0	-2.1	-1.8	-2.1	-0.9	-1.1	-1.2	-1.7	-2.2
Depression (Nagel 2018)	0.3	0.5	0.6	-0.8	-0.6	-0.7	0.8	-0.7	-0.7	-0.3	-0.7
Intelligence (Savage-Jansen 2018)	1.9	5.7	9.4	2.2	1.7	3.0	2.4	2.3	2.1	3.1	2.0
Neuroticism (Nagel 2018)	1.1	2.6	5.7	-2.2	-2.0	-1.5	0.0	-0.5	-0.7	-1.6	-2.4
Schizophrenia (2018)	0.0	0.1	0.4	0.0	-0.1	-0.3	-0.6	0.3	0.3	0.2	-0.3
Schizophrenia vs Biploar Disorder	0.2	0.2	0.6	0.5	-0.1	0.7	0.8	-0.3	-0.1	0.6	0.4
Worry (Nagel 2018)	1.4	3.0	7.5	-2.5	-2.5	-0.3	0.0	-0.9	-1.2	-1.3	-2.7
Alzheimer’s Disease (in mother)	0.5	0.5	2.2	-0.8	-0.7	-0.5	-1.5	0.1	-0.2	-0.2	-0.9
Alzheimer’s Disease (in father)	0.3	0.4	0.8	-0.7	-0.5	0.3	0.3	0.8	0.4	0.7	-0.9
Alzheimer’s Disease (including proxy)	0.4	0.5	1.3	-1.0	-0.8	0.1	-0.5	0.7	0.3	0.7	-1.1
Crohns Disease (2017)	0.4	0.8	3.5	-0.1	0.6	-0.7	-0.1	0.9	1.0	-1.9	0.1
Irritable Bowel Disease (IBD)	0.2	0.4	1.8	-0.5	-0.1	0.2	0.6	0.6	0.5	-1.4	-0.3
Ulcerative Colitis (UC)	0.3	0.5	1.6	-0.2	-0.1	1.2	1.3	0.8	0.6	-0.0	-0.2
Major Depression (MDD)	1.7	2.0	11.3	0.7	0.9	0.7	3.4	1.1	0.8	0.7	0.9
Reaction Time	0.7	1.3	2.8	1.4	1.0	-1.1	0.5	1.1	0.9	1.7	1.1
Verbal and Numeric Reasoning (VNR)	0.9	2.2	4.9	1.2	1.0	1.8	1.8	1.2	1.2	2.2	1.1
Breast Cancer	0.3	0.8	2.4	0.8	0.5	-0.8	0.5	1.6	1.4	0.1	0.6
Ovarian Cancer	0.3	0.4	2.1	0.7	0.0	-1.5	-0.2	-0.3	-0.2	0.2	0.6
Prostate Cancer	1.3	1.9	3.8	1.5	2.0	-0.8	0.3	1.6	1.8	0.4	1.5
Age at First Birth	0.2	0.3	1.7	0.6	-0.2	0.6	0.3	0.1	-0.1	1.3	0.4
Bipolar Disorder (2011)	2.2	2.1	3.8	1.9	1.9	0.8	0.4	1.1	1.4	1.4	1.9
Body Mass Index (BMI) (2010)	1.1	1.5	2.7	-1.6	-1.3	-1.2	-1.0	-0.1	-0.4	-1.6	-1.6
Coronary Artery Disease (CAD)	0.6	0.8	1.8	1.2	0.8	-0.6	-0.6	-0.0	0.3	1.3	1.2
Crohns Disease (2012)	0.6	0.9	1.6	0.8	1.2	0.9	1.2	1.0	1.3	-0.3	0.8
Mean Putamen Volume	1.2	1.4	2.5	-1.3	-1.6	-0.9	-0.2	-1.4	-1.4	-0.2	-1.5
Fasting Glucose	0.2	0.2	0.6	-0.2	-0.3	0.5	0.6	-0.1	-0.2	0.8	-0.1
HbA1C	0.4	0.4	1.5	-0.4	-0.5	-0.4	-1.2	-0.1	-0.0	-1.0	-0.6
HDL Cholesterol	1.7	2.8	7.0	-1.3	-1.1	-0.6	-2.7	-1.9	-1.6	-2.1	-1.2
LDL Cholesterol	1.8	2.9	5.4	-2.3	-1.7	-0.8	-0.5	-1.9	-1.8	-1.5	-2.1
Lupus	2.4	3.6	5.6	2.4	1.8	0.8	-0.3	2.3	2.4	2.1	2.1
Neuroticism (2016)	2.6	3.8	7.4	-2.7	-2.4	-0.3	-0.3	-1.3	-1.5	-2.3	-2.7
Primary Biliary Cirrhosis	0.7	1.0	4.1	0.1	0.7	-2.0	-1.3	0.7	0.7	-0.8	0.1
Rheumatoid Arthritis	0.5	0.7	1.5	0.7	1.0	-1.1	-0.1	1.1	1.2	0.4	0.4
Schizophrenia (2014)	0.1	0.3	0.5	0.7	0.4	0.3	-0.6	0.7	0.6	0.1	0.6
Triglycerides	0.4	0.6	1.6	-1.0	-1.0	-0.3	1.3	-0.3	-0.5	0.1	-0.9
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.7	0.4	0.7	-1.3	0.5	0.5	0.7	0.9	0.3
Ulcerative Colitis	0.6	0.9	4.0	0.6	0.4	2.0	1.1	0.8	0.7	0.5	0.6
Blood Eosinophil Count	0.1	0.6	3.1	-0.0	0.2	1.8	1.0	-0.3	-0.3	0.8	-0.1
Blood Platelet Count	0.1	1.4	3.1	-1.3	-1.5	-0.6	-0.4	-1.5	-1.8	-0.2	-1.1
Blood Red Count	0.0	0.2	0.8	0.3	0.1	-0.9	-0.2	-0.6	-0.2	0.1	0.3
Blood White Count	0.5	3.8	8.8	-2.2	-1.9	-0.9	-1.6	-1.5	-1.8	-3.0	-2.0
Heel T-Score	3.9	31.2	55.7	4.6	4.8	7.5	7.4	4.4	4.7	5.7	4.5
BMI	0.2	1.3	2.6	-1.5	-1.3	-0.3	-0.9	-0.7	-0.7	-1.5	-1.6
Height	0.0	0.7	1.8	-0.1	-0.1	-0.6	1.4	1.2	0.8	-1.3	0.1
Waist Hip Ratio (WHR)	0.4	1.9	5.6	-2.1	-1.2	-1.5	-0.7	0.6	0.1	-0.1	-2.4
Systolic Blood Pressure	0.1	0.7	2.4	-0.2	-0.3	-0.7	-1.6	-1.2	-0.8	-0.8	-0.1
Smoking Status	0.2	0.4	1.3	0.7	0.6	0.2	1.2	0.5	0.6	-0.0	0.7
Allergy or Eczema	0.3	0.7	3.2	-0.3	-0.6	-1.8	-0.5	-1.0	-0.9	-0.0	-0.3
Cardiovascular Disease	0.4	1.2	2.4	-1.2	-0.9	0.6	-1.6	-0.5	-0.7	-1.3	-1.3
Hypothyroidism (self reported)	1.3	2.9	5.0	2.1	2.0	0.3	0.3	2.0	2.2	1.8	1.7
Respiratory disease	0.7	1.6	2.7	-1.1	-1.4	-1.6	1.0	-0.9	-1.0	-1.6	-1.3
Type 2 Diabetes (T2D) (2018)	0.2	0.5	2.1	0.4	0.5	1.4	0.1	-0.4	-0.2	0.9	0.4
Lung FEV1/FVC ratio	0.8	4.3	8.1	1.8	2.2	1.8	0.4	2.8	2.9	2.0	1.7
Lung FVC	0.7	3.5	7.7	2.7	2.0	0.3	0.1	0.5	0.9	2.7	2.8
Neuroticism	2.5	6.0	13.4	-3.4	-3.3	-1.2	-0.1	-1.7	-2.1	-1.8	-3.7
Chronotype (morning person)	2.7	6.3	10.0	-3.2	-2.7	-0.8	-1.9	-2.4	-2.4	-2.8	-3.1
Hair Pigment	0.0	1.0	2.5	1.3	1.2	-0.2	0.2	1.0	1.0	0.2	1.6
Tanning	0.5	5.9	9.8	-3.0	-2.8	0.3	-0.7	-2.3	-2.5	-3.1	-3.0
Hand grip strength (left)	0.1	0.2	0.6	-0.4	-0.5	-0.7	0.2	-0.1	-0.1	-0.8	-0.6
Number of treatments/medications taken	0.9	1.6	3.7	0.7	1.2	1.1	1.5	1.9	1.7	0.4	0.6
Average weekly spirits intake	0.1	0.2	0.9	0.0	0.4	0.9	0.5	0.2	0.2	0.2	0.1
Sensitivity / hurt feelings	0.6	1.1	1.9	-1.1	-1.0	-1.3	1.4	0.1	-0.2	-1.1	-1.2
Frequency of depressed mood in last 2 weeks	1.1	1.5	2.8	-1.7	-1.6	0.5	0.3	-0.9	-1.1	-1.5	-1.6
Hearing difficulty/problems: Yes	1.2	1.8	3.2	1.3	1.6	0.6	0.9	1.8	1.7	1.4	1.2
Relative age of first facial hair	0.8	1.7	3.5	-1.9	-1.3	-1.0	1.2	0.4	-0.2	-1.6	-1.8
Other serious medical condition/disability diagnosed by doctor	1.8	2.4	5.3	-2.2	-1.6	1.0	-1.3	0.1	-0.3	-1.9	-2.3
Ever used hormone-replacement therapy (HRT)	2.1	2.7	4.1	1.9	2.0	0.1	0.7	1.7	2.0	1.9	1.7
Ever had hysterectomy (womb removed)	1.4	1.5	3.6	-1.5	-1.1	-1.9	-0.3	-1.0	-1.0	-0.9	-1.5
Systolic blood pressure, automated reading	0.1	0.4	2.8	0.1	0.4	0.3	-1.7	-0.5	0.1	0.4	-0.0
Eye problems/disorders: Diabetes related eye disease	3.8	4.2	9.4	2.8	2.2	1.1	0.8	1.1	1.3	2.5	3.1
Angina	0.1	0.2	0.9	0.0	-0.2	0.3	0.5	0.1	-0.0	0.9	-0.1
Medication for hormone replacement therapy	0.2	0.2	1.6	-0.1	-0.5	0.0	-1.2	-0.3	-0.3	-0.0	-0.0
Vitamin and mineral supplements	0.6	0.8	5.3	0.1	-0.5	-0.8	-0.3	-0.4	-0.6	-2.3	0.4
Supplements: Zinc	1.4	1.5	5.1	1.5	1.1	0.4	0.6	0.5	0.6	2.3	1.5
Medication: Co-codamol	0.6	0.7	2.0	-1.0	-1.4	-0.0	-0.6	-0.7	-0.9	-0.2	-0.9
Medication: Metformin	0.2	0.3	1.1	-0.1	0.3	0.6	0.5	-0.5	-0.4	1.0	-0.1
Diabetes (father)	0.7	0.8	3.8	-0.2	-0.8	1.9	0.4	-0.7	-0.8	0.9	-0.2
Diabetes (mother)	0.3	0.4	1.0	-0.6	-1.0	1.0	0.5	-0.4	-0.6	0.2	-0.5
Severe depression (siblings)	0.4	0.5	2.4	0.1	0.7	1.5	-0.8	-0.4	-0.2	0.1	0.4
Pack years adult smoking proportion	0.6	0.9	2.7	0.3	0.5	0.3	1.1	1.6	1.5	-0.9	0.2
Impedance of leg (right)	0.1	0.5	1.1	0.8	0.2	-0.9	-1.1	-0.5	-0.3	0.6	1.0
Leg fat-free mass (left)	0.1	0.6	1.9	0.3	0.4	-0.1	1.0	1.4	1.2	-0.2	0.0
Trunk fat percentage	0.2	0.6	4.2	0.4	0.4	-0.4	-2.1	0.3	0.5	-0.0	0.2
Hand grip strength (right)	0.1	0.3	1.3	0.6	0.5	-0.5	1.2	-0.1	0.1	0.2	0.7
Townsend deprivation index at recruitment	0.3	0.5	1.5	-0.0	0.2	-1.2	-0.5	0.9	0.6	-0.8	0.3
Current tobacco smoking	0.5	0.9	1.5	1.0	1.2	-0.6	1.2	0.5	0.8	-0.5	1.1
Average weekly fortified wine intake	0.4	0.4	1.3	0.3	0.6	1.1	0.8	-0.6	-0.4	0.2	0.5
Maternal smoking around birth	0.2	0.3	1.8	0.2	0.0	1.4	-0.4	-0.4	-0.3	-0.2	0.2
Fed-up feelings	2.8	5.0	8.8	-2.7	-2.4	-2.5	-1.5	-0.9	-1.2	-2.8	-3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.8	-0.2	-0.3	-0.9	0.7	-0.1	-0.2	-0.7	-0.2
Relative age voice broke	1.1	1.7	4.4	-2.1	-1.3	-0.2	0.3	0.1	-0.4	-1.7	-2.0
Taking other prescription medications	0.4	0.7	1.9	0.1	0.3	1.4	0.5	1.2	1.0	0.6	-0.1
Age when periods started (menarche)	0.1	0.2	0.6	0.4	0.4	-0.3	-0.2	0.8	0.6	-0.6	0.2
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	6.9	0.2	0.3	-2.6	-1.4	0.2	0.4	-0.4	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.2	1.5	1.2	0.8	0.7	0.8	1.0	0.5	1.3
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.7	-1.3	-1.2	-0.3	0.9	-0.4	-0.9	-0.0	-1.3
Qualifications: CSEs or equivalent	1.0	1.3	2.6	-0.7	-1.0	-0.8	-1.4	-1.3	-1.1	-1.6	-0.6
Serious illness, injury or assault to yourself	0.1	0.1	0.5	0.1	-0.2	0.7	-0.4	0.2	-0.0	-0.2	0.1
High blood pressure	0.3	0.7	4.2	0.4	0.7	2.1	-0.2	0.2	0.2	0.6	0.6
Hayfever, allergic rhinitis or eczema	0.6	1.2	3.3	-0.4	-1.2	-1.8	-0.4	-1.4	-1.5	-0.6	-0.4
Multivitamins +/- minerals	1.2	1.5	5.7	-0.0	0.3	2.0	1.3	0.5	0.6	2.4	-0.3
Stomach or abdominal pain in last month	1.0	1.2	2.8	-1.5	-1.7	0.2	0.3	-0.7	-1.1	-1.2	-1.2
Supplements: Glucosamine	1.2	1.6	3.2	0.0	0.6	1.4	1.6	1.8	1.7	1.2	-0.3
Diverticular disease/diverticulitis (self-reported)	4.4	5.2	9.9	-2.1	-2.9	1.4	-1.8	-2.9	-3.1	-1.5	-1.8
Medication: Atenolol	0.7	0.9	3.6	0.1	0.4	1.9	1.5	0.5	0.5	0.6	0.0
Medication: Levothyroxine sodium	1.6	2.8	5.9	2.0	2.2	0.1	-0.6	2.0	2.4	1.0	1.6
Sitting height	0.4	2.6	5.4	1.9	1.5	-0.7	2.3	1.5	1.5	1.0	1.9
Chronic bronchitis/emphysema (father)	0.5	0.6	2.1	0.2	-0.3	0.7	-0.5	-1.5	-1.1	0.6	0.2
High blood pressure (mother)	0.7	1.0	2.4	-1.1	-1.5	0.1	0.1	-0.8	-0.9	-1.0	-1.4
Body mass index (BMI)	0.1	0.6	1.8	-0.7	-0.6	-0.4	-1.4	-0.6	-0.4	-0.8	-0.9
Impedance of leg (left)	0.1	0.7	1.3	0.7	0.1	-0.9	-1.1	-1.0	-0.8	0.5	1.0
Leg predicted mass (left)	0.1	0.5	1.6	0.2	0.4	-0.2	0.9	1.3	1.1	-0.2	-0.0
Trunk fat mass	0.1	0.4	1.7	0.4	0.5	-0.2	-1.3	0.5	0.7	0.0	0.3
Waist circumference	0.1	0.3	1.5	-0.4	-0.1	-0.6	-1.2	0.3	0.4	-0.1	-0.6
Number of incorrect matches in round	0.4	0.6	2.4	0.2	-0.4	0.5	-1.5	-1.0	-0.9	-0.3	0.4
Past tobacco smoking	0.5	0.9	3.8	-0.2	-0.2	-0.9	-1.9	-1.1	-0.6	-0.8	-0.2
Alcohol usually taken with meals	0.9	1.5	4.5	1.1	1.1	0.6	2.1	1.3	1.3	0.6	0.9
Nervous feelings	1.7	3.1	4.9	-2.0	-2.2	0.5	-1.8	-1.5	-1.5	-1.8	-2.2
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.5	-1.4	-1.2	-0.8	-0.6	-0.4	-0.6	-1.6	-1.5
Hearing difficulty/problems with background noise	0.4	0.6	1.7	0.7	1.3	-0.4	-0.4	0.8	1.0	-0.4	0.8
Hair/balding pattern: Pattern 2	1.3	1.6	4.0	-0.9	-1.0	-1.1	-2.0	-1.4	-1.2	-1.3	-0.8
Had menopause	1.9	2.3	3.9	1.9	1.8	1.5	-0.7	0.8	1.2	1.8	2.0
Had other major operations	0.9	1.1	2.3	-1.5	-1.3	-1.1	-0.2	0.0	-0.4	-1.2	-1.4
Forced vital capacity (FVC)	0.1	0.5	1.4	0.9	0.6	0.3	0.6	0.3	0.2	0.8	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	0.9	1.0	0.5	0.7	0.7	0.8	0.0	0.7
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.2	0.4	-0.4	0.1	-0.8	-1.1	-1.0	-0.4	0.6
Qualifications: None of the above	1.9	4.1	6.7	-2.0	-2.0	-1.6	-2.6	-1.7	-1.6	-2.5	-1.9
Financial difficulties in last 2 years	0.1	0.1	0.5	-0.5	-0.1	-0.1	-0.3	-0.3	-0.3	-0.7	-0.3
Mouth/teeth dental problems	0.2	0.3	1.6	0.5	0.3	-0.4	1.3	-0.3	-0.1	0.2	0.4
Heart attack	0.5	0.6	2.3	0.7	0.3	0.1	1.5	0.6	0.5	-0.8	0.8
Allergy	0.7	1.7	3.2	0.9	1.7	1.8	-0.0	1.4	1.6	1.0	0.9
Pain all over the body in last month	0.3	0.4	1.8	0.2	0.1	-1.3	0.2	0.3	0.4	-0.8	-0.2
Diabetes (self-reported)	0.2	0.3	1.2	0.3	0.4	1.1	0.6	-0.5	-0.4	0.4	0.4
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.2	-1.5	-1.5	-1.0	0.5	0.9	0.1	-0.5	-1.8
Medication: Ramipril	0.8	1.1	5.9	-0.4	-0.5	2.4	-0.3	-1.0	-0.9	-0.4	-0.3
Medication: Simvastatin	0.2	0.3	0.6	-0.8	-0.4	0.6	0.7	0.2	0.0	-0.1	-0.8
Fluid intelligence score	1.0	2.0	5.0	1.0	0.9	1.9	1.0	1.4	1.4	2.2	0.9
Illnesses of siblings	0.6	0.8	2.9	-0.5	-0.6	-1.0	-1.0	-0.5	-0.5	-1.7	-0.4
Neuroticism score	3.5	7.3	13.8	-3.6	-3.6	-1.2	-1.0	-1.6	-2.2	-3.0	-3.7
Weight	0.0	0.1	0.4	0.1	0.2	-0.1	-0.1	0.6	0.6	-0.2	-0.0
Impedance of arm (right)	0.1	0.4	2.7	0.2	-0.2	-0.2	-1.7	0.3	0.0	0.0	0.3
Arm fat percentage (right)	0.2	0.8	4.3	-0.7	-0.6	-0.4	-2.1	-0.4	-0.3	-0.6	-0.8
Trunk fat-free mass	0.2	1.0	5.8	0.2	0.5	-0.1	2.4	1.1	1.0	0.5	0.0
Hip circumference	0.0	0.1	0.6	0.2	0.0	-0.4	-0.7	0.1	0.2	-0.2	0.1
Time employed in main current job	0.7	0.8	1.7	-1.0	-1.3	0.4	0.4	-0.5	-0.9	-1.1	-1.0
Alcohol intake versus 10 years previously	0.9	1.3	2.7	-1.6	-1.0	-1.6	0.7	-0.7	-0.6	-0.7	-1.6
Father’s age at death	3.3	4.4	7.7	2.4	2.8	1.5	1.5	1.7	2.1	2.0	2.4
Worrier / anxious feelings	2.5	4.7	11.6	-3.1	-3.0	-0.1	-0.4	-1.2	-1.6	-1.6	-3.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.7	-0.3	-0.8	0.9	0.2	-0.2	-0.3	-0.4	-0.5
Falls in the last year	0.7	1.0	2.3	-1.0	-1.4	-0.2	-1.5	-0.5	-0.9	-0.8	-0.9
Hair/balding pattern: Pattern 3	0.5	0.8	3.9	-0.1	-0.4	2.0	1.3	0.5	0.1	-0.2	-0.1
Number of live births	0.9	1.3	2.5	-0.8	-1.1	-0.6	-1.2	-1.6	-1.5	-1.2	-0.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.7	0.6	0.5	0.3	0.2	0.4	0.3	0.5	0.8
Pulse rate	0.3	0.5	1.2	0.5	0.4	0.2	-0.9	1.1	1.1	-0.6	0.4
Happiness	0.3	0.4	1.7	0.0	-0.0	1.3	0.9	-0.1	-0.0	-0.7	0.1
Noisy workplace	0.1	0.1	0.2	0.1	0.3	-0.4	0.5	-0.4	-0.3	-0.2	0.3
Qualifications: A levels/AS levels or equivalent	2.1	4.6	7.6	2.5	2.1	1.2	1.4	2.3	2.1	2.7	2.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.6	-0.3	0.1	-0.0	0.8	-0.2	-0.3	0.3	-0.1
Mouth/teeth dental problems: Dentures	0.6	1.0	5.0	-0.6	-0.1	2.2	0.2	1.0	0.8	0.2	-0.9
Asthma	1.0	2.0	4.5	-1.0	-1.7	-1.1	-0.4	-2.1	-2.1	-1.3	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	1.4	0.6	0.7	-0.6	0.8	0.7	0.7	1.2	0.5
Medication: Cholesterol lowering	0.6	0.9	3.3	0.5	0.9	0.5	1.2	0.8	0.8	1.8	0.3
Depression (self-reported)	1.0	1.2	4.6	-0.1	-0.5	-1.1	-2.1	-1.0	-0.8	-1.3	-0.1
Medication: Lansoprazole	0.2	0.2	0.9	-0.1	0.1	0.4	0.3	0.3	0.3	-1.0	-0.2
Prospective memory result	3.3	4.1	7.6	-2.8	-2.5	-0.6	0.7	-1.9	-2.2	-1.2	-2.7
Lung cancer (father)	0.8	0.9	2.0	-0.9	-0.7	0.5	-0.8	-1.2	-1.0	-1.4	-0.7
Illnesses of mother	0.1	0.2	0.7	0.3	0.3	-0.8	0.5	-0.3	-0.2	0.3	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	2.2	1.2	1.0	-0.7	-0.3	0.8	0.8	0.2	1.5
Pulse wave Arterial Stiffness index	1.5	1.7	5.6	-1.0	-0.3	-1.9	0.0	1.3	0.8	-2.4	-0.9
Impedance of arm (left)	0.1	0.3	1.5	0.4	0.0	0.3	-1.2	0.6	0.3	0.1	0.5
Arm fat mass (right)	0.1	0.3	1.8	-0.3	-0.3	-0.2	-1.3	-0.0	0.0	-0.4	-0.5
Trunk predicted mass	0.2	0.9	5.6	0.0	0.3	-0.0	2.4	0.9	0.8	0.4	-0.1
Standing height	0.3	2.7	6.9	1.4	1.4	0.2	2.6	2.1	1.8	1.0	1.5
Length of working week for main job	0.5	0.5	1.0	-0.8	-0.8	0.6	-0.9	-0.3	-0.3	-1.0	-0.7
Exposure to tobacco smoke at home	0.7	0.7	3.0	0.7	0.6	-1.7	-1.0	-0.2	-0.0	0.7	0.8
Breastfed as a baby	0.5	0.6	1.8	-0.9	-1.4	0.4	-0.4	-0.3	-0.6	0.3	-1.1
Tense / ‘highly strung’	1.1	1.8	7.2	-1.4	-1.7	0.0	-0.4	-0.2	-0.7	-2.7	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.4	7.9	-2.5	-2.8	-0.9	0.2	-2.2	-2.5	-2.0	-2.3
Hair/balding pattern: Pattern 4	3.1	7.6	19.4	3.1	3.2	1.3	1.2	2.0	2.4	4.4	2.9
Birth weight of first child	0.3	0.5	2.0	0.1	0.1	-0.9	-1.4	-0.5	-0.4	-0.7	0.3
Peak expiratory flow (PEF)	0.1	0.3	1.0	0.6	0.3	1.0	-0.0	-0.0	0.1	-0.0	0.8
Pulse wave reflection index	1.4	1.7	3.1	-1.3	-1.1	-1.6	-1.2	-0.9	-1.3	-1.8	-1.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.8	-1.1	-0.5	-1.4	-0.9	-0.9	-1.0	-1.3	-0.8
Loud music exposure frequency	1.1	1.2	2.7	1.3	1.6	0.7	0.3	0.5	0.8	1.5	1.3
Qualifications: O levels/GCSEs or equivalent	1.0	1.7	5.5	1.3	0.7	0.2	1.3	1.2	1.0	2.4	1.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	-0.4	-0.6	0.2	-0.7	-0.1	-0.4	0.2	-0.4
Blood clot in the leg (DVT)	0.3	0.4	0.8	-0.8	-0.6	-0.3	-0.5	0.3	0.0	0.8	-0.9
Medication: Paracetamol	0.8	1.4	3.1	-0.9	-1.6	-1.8	-0.5	-1.1	-1.3	0.4	-1.1
Headache pain in last month	0.5	0.9	1.8	0.7	0.7	-1.3	1.3	0.7	0.7	1.2	0.6
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.5	0.3	-0.0	-0.3	-0.7	0.1	0.1	-0.7	0.4
Glaucoma (self-reported)	0.5	0.6	1.5	-0.4	-0.2	0.5	1.2	1.2	0.9	0.0	-0.6
Gout (self-reported)	1.1	1.5	3.3	-1.4	-1.2	-0.9	-1.4	-0.8	-0.8	-0.9	-1.8
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	5.1	2.1	1.8	0.9	0.6	2.1	2.3	1.6	1.8
Medication: Amlodipine	0.2	0.3	0.7	0.7	0.6	0.5	-0.5	0.1	0.3	0.2	0.8
Medication: Ventolin 100micrograms inhaler	1.0	1.2	3.0	1.0	1.3	0.2	0.9	1.7	1.7	0.3	0.8
Birth weight	0.2	0.5	0.9	-0.5	-0.6	-0.9	0.9	0.6	0.4	-0.8	-0.7
Chronic bronchitis/emphysema (mother)	1.7	2.0	2.6	-1.4	-1.4	1.5	-1.5	-1.4	-1.6	-1.5	-1.0
High blood pressure (siblings)	0.3	0.4	1.1	-0.3	-0.4	0.6	1.1	-0.2	-0.2	1.0	-0.3
Forced vital capacity (FVC), Best measure	0.3	0.9	2.4	1.4	1.1	-0.8	-0.0	0.8	0.8	0.2	1.6
Body fat percentage	0.1	0.6	3.6	0.4	0.5	-0.4	-1.9	0.2	0.4	0.1	0.3
Leg fat percentage (right)	0.1	0.5	3.3	-0.0	0.0	-0.7	-1.8	-0.5	-0.2	-0.2	-0.2
Arm fat-free mass (right)	0.1	0.6	2.4	0.3	0.6	0.0	1.5	0.9	1.0	0.3	0.2
Exposure to tobacco smoke outside home	0.8	1.0	7.1	-0.5	-0.6	-2.7	0.4	-0.0	-0.2	0.1	-0.6
Comparative body size at age 10	0.7	1.9	4.0	-1.7	-1.6	-0.2	0.3	-1.7	-2.0	-0.1	-1.6
Number of full brothers	0.7	0.8	1.3	1.2	1.1	-0.0	1.0	0.9	0.9	-0.0	1.2
Worry too long after embarrassment	0.2	0.4	1.1	0.1	0.1	-0.0	1.1	0.8	0.8	-0.8	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	4.0	-2.0	-1.8	-0.9	-1.0	-0.8	-1.1	-1.9	-1.9
Wheeze or whistling in the chest in last year	0.9	1.7	3.3	1.0	0.5	-0.7	1.8	1.8	1.7	1.6	0.3
Number of children fathered	0.8	0.9	2.1	-0.9	-1.2	1.4	-0.7	-0.5	-0.6	-0.6	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	2.6	-1.4	-1.0	-0.6	-0.9	0.4	0.1	-0.9	-1.6
Age at first live birth	0.1	0.1	0.8	-0.0	0.3	-0.9	-0.2	0.1	0.2	0.1	-0.0
Pulse wave peak to peak time	1.6	1.9	6.2	1.3	0.5	2.1	0.3	-1.0	-0.5	2.5	1.2
Health satisfaction	0.6	0.8	3.2	0.6	0.0	1.8	1.3	-0.1	-0.1	0.7	0.6
Shortness of breath walking on level ground	1.0	1.2	5.1	0.8	0.8	0.7	2.3	0.7	0.6	0.7	0.9
Qualifications: College or University degree	0.7	2.2	4.4	1.3	1.2	2.1	1.6	1.4	1.0	1.6	1.5
Eye problems/disorders: None of the above	1.5	1.7	2.8	-1.1	-1.0	-0.6	-1.6	-1.5	-1.6	-1.7	-0.9
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.7	0.0	0.0	0.6	0.4	0.6	0.4	-0.8	0.1
Emphysema/chronic bronchitis	1.3	1.5	4.6	1.2	1.0	-0.3	2.1	1.2	1.4	0.7	1.1
Medication for pain relief, constipation, heartburn	0.6	1.0	3.0	1.5	1.4	0.4	0.1	-0.3	0.3	0.2	1.7
Neck or shoulder pain in last month	1.1	1.5	3.3	-1.5	-1.8	-0.5	-0.3	-1.2	-1.7	-0.7	-1.2
Medication: Blood pressure	0.2	0.3	1.4	-0.2	-0.1	0.8	1.2	0.3	0.1	0.6	-0.3
Angina (self-reported)	0.1	0.1	0.8	-0.0	-0.1	0.3	0.2	0.0	-0.1	0.9	-0.2
Migraine (self-reported)	4.8	5.9	10.4	2.7	3.2	0.7	2.7	1.9	2.2	2.2	2.9
Medication: Ibuprofen	0.1	0.2	1.0	0.0	0.0	-1.0	-0.1	-0.1	-0.1	0.4	-0.1
Medication: Allopurinol	1.0	1.3	4.4	-1.7	-1.1	-0.5	-1.1	-0.1	-0.2	-0.5	-2.1
Medication: Omeprazole	0.8	0.9	2.5	-1.3	-1.5	-0.1	-0.9	-0.0	-0.3	-0.4	-1.6
Medication: Seretide 50 evohaler	1.6	1.8	4.9	0.7	1.2	-0.5	2.2	2.0	1.8	0.2	0.6
Mean time to correctly identify matches	1.3	2.5	5.0	1.7	1.7	-0.9	0.2	1.8	1.8	2.2	1.4
Heart disease (mother)	3.4	4.1	6.3	2.4	2.4	1.1	1.5	2.3	2.5	1.0	2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.7	3.2	7.2	2.6	2.3	1.4	-0.1	0.8	1.4	1.4	2.7
Whole body fat mass	0.1	0.3	1.5	0.3	0.4	-0.4	-1.2	0.3	0.5	-0.0	0.2
Leg fat mass (right)	0.1	0.2	1.3	0.2	0.3	-0.2	-1.2	0.0	0.2	-0.1	0.0
Arm predicted mass (right)	0.1	0.6	3.0	0.3	0.5	-0.1	1.7	0.8	0.9	0.3	0.2
Pulse rate, automated reading	0.2	0.7	2.3	0.3	0.7	-0.7	0.2	1.5	1.4	0.0	0.2
Alcohol intake frequency.	0.4	0.9	2.7	0.8	0.8	-0.0	1.6	0.4	0.7	1.3	0.9
Comparative height size at age 10	0.0	0.0	0.2	0.1	-0.1	-0.1	0.2	0.4	0.3	-0.2	-0.1
Number of full sisters	0.2	0.2	1.2	0.2	0.3	0.1	0.3	0.4	0.6	1.1	-0.0
Suffer from ‘nerves’	2.1	3.3	5.6	-2.2	-2.4	-0.3	-1.7	-1.4	-1.5	-2.1	-2.2
Overall health rating	0.2	0.5	1.1	-0.6	-1.0	0.3	0.4	-0.7	-0.8	-0.6	-0.7
Chest pain or discomfort	1.7	2.4	5.6	2.0	1.6	0.9	1.0	1.1	1.3	2.4	1.7
Had major operations	0.3	0.4	0.9	0.7	0.8	0.6	0.9	-0.0	0.2	-0.2	0.9
Age at last live birth	0.5	0.7	1.6	-0.9	-0.3	-1.2	-0.6	-1.0	-0.7	-0.3	-1.0
Family relationship satisfaction	0.9	1.1	5.0	-0.7	-0.4	-0.4	-0.3	-1.3	-1.2	-2.2	-0.3
Leg pain on walking	0.2	0.2	0.9	0.1	-0.6	0.9	0.6	0.2	-0.1	0.4	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.9	1.7	1.4	-0.6	-0.2	0.3	0.6	0.9	1.7
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	0.6	-0.1	-0.0	-0.6	-0.2	0.0	-0.1	0.4
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	5.3	-0.7	-1.1	-1.6	-2.3	-1.0	-0.9	-0.6	-1.0
Medication: Aspirin	0.4	0.5	2.7	-0.1	-0.1	1.6	-0.2	0.7	0.4	0.4	-0.4
Supplements: Vitamin C	0.6	0.7	2.1	-0.7	0.0	-1.3	-1.5	-1.0	-0.7	0.0	-0.5
Knee pain experienced in last month	0.2	0.3	1.1	0.0	-0.2	0.9	0.7	-0.2	-0.3	1.0	0.0
Hypertension (Self-reported)	0.1	0.4	2.5	-0.3	0.1	1.6	-0.5	-0.1	-0.2	0.1	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.4	-0.9	-1.0	-0.9	-0.1	-0.5	-0.5	-1.2	-1.1
Illnesses of father: Heart disease	2.8	3.8	6.8	2.2	2.1	-0.0	1.1	2.2	2.3	2.6	1.9
Illnesses of siblings: Diabetes	2.7	3.3	5.3	2.1	2.2	-0.2	1.6	1.5	1.9	2.3	1.9
Smoking status: Previous	0.7	1.1	4.2	0.4	0.3	0.8	2.0	1.3	0.8	0.9	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.5	0.2	0.4	-1.9	-0.4	-0.2	-0.0	-1.5	0.3
Whole body fat-free mass	0.1	0.7	3.2	0.2	0.4	0.0	1.8	1.1	1.0	0.2	0.0
Leg fat-free mass (right)	0.1	0.6	1.6	0.2	0.4	-0.1	1.2	1.2	1.1	-0.2	0.0
Arm fat percentage (left)	0.2	0.8	4.2	-0.6	-0.5	-0.1	-2.1	-0.4	-0.3	-0.7	-0.7
Average weekly red wine intake	0.3	0.4	0.8	-0.8	-0.7	0.5	-0.1	0.2	-0.1	-0.9	-0.9
Handedness (chirality/laterality): Left-handed	0.6	0.7	4.0	-0.5	-0.8	2.0	0.4	-0.0	-0.4	-0.4	-0.4
Mood swings	1.6	3.0	4.6	-2.1	-2.1	-1.2	-1.0	-1.4	-1.5	-1.9	-2.1
Loneliness, isolation	1.4	2.0	7.1	-1.6	-0.5	-0.7	0.6	1.2	0.8	-2.7	-1.8
Long-standing illness, disability or infirmity	0.2	0.3	0.8	-0.0	0.1	0.2	0.9	0.9	0.8	-0.2	-0.3
Ever had bowel cancer screening	1.1	1.3	9.9	-0.3	-0.1	3.1	0.0	-0.1	0.1	0.2	-0.1
Diabetes diagnosed by doctor	0.2	0.4	1.3	0.3	0.5	1.1	-0.0	-0.6	-0.4	0.8	0.4
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.1	3.6	-1.1	-1.4	-1.3	-1.3	-1.9	-1.8	-1.6	-0.9
Friendships satisfaction	0.3	0.3	1.1	0.5	0.4	-1.1	0.1	-0.1	0.1	-0.7	0.8
Qualifications: nursing, teaching	1.3	2.1	3.6	0.8	1.3	1.2	1.8	1.9	1.7	1.7	0.6
Commuting to job workplace: Walk	2.2	2.4	3.9	-1.9	-1.5	-0.1	-2.0	-1.0	-1.3	-1.9	-1.7
Eye problems/disorders: Cataract	0.7	0.8	1.6	0.7	0.9	-0.7	0.6	1.1	1.3	1.0	0.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.0	1.2	1.4	0.2	-1.0	0.9	1.2	0.5	1.3
Medication for cholesterol	0.2	0.3	1.7	0.3	0.4	-1.3	0.4	-0.2	-0.0	-0.0	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	4.1	-1.9	-1.3	-0.0	0.2	-0.3	-0.7	-2.0	-1.8
Back pain experienced in last month	0.6	0.8	1.4	-0.9	-1.2	-1.1	-0.2	-1.0	-1.1	-0.4	-0.8
Mineral and other dietary supplements	4.6	6.2	8.8	-2.1	-2.4	-2.9	-2.1	-2.5	-2.8	-3.0	-1.9
Breast cancer (self-reported)	0.7	0.8	2.3	-1.3	-0.9	0.5	0.2	0.2	-0.2	-1.5	-1.3
Asthma (self-reported)	0.8	1.6	3.4	-0.9	-1.6	-0.8	0.0	-1.7	-1.8	-1.2	-0.9
Osteoporosis (self-reported)	0.5	0.6	2.3	-0.1	-0.4	-1.3	-1.5	-0.7	-0.5	-0.2	-0.2
Osteoarthritis (self-reported)	0.1	0.2	0.8	-0.1	-0.1	-0.3	0.9	0.4	0.4	0.2	-0.3
Medication: Aspirin	0.3	0.4	1.8	-0.6	-0.3	1.3	-0.5	0.3	0.1	0.1	-0.8
Medication: Gliclazide	0.2	0.2	0.8	0.1	0.2	-0.9	-0.6	-0.2	0.0	0.7	-0.1
Illnesses of father: None of the above (group 1)	3.2	4.0	9.0	-2.3	-1.9	-0.5	-1.8	-1.6	-1.7	-3.0	-2.2
Smoking status: Current	0.2	0.3	0.5	0.6	0.7	-0.6	0.7	-0.0	0.3	-0.6	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.3	0.3	0.2	0.8	0.7	0.4	0.4	0.5
Whole body water mass	0.1	0.7	2.9	0.2	0.5	-0.1	1.7	1.2	1.1	0.1	0.0
Leg predicted mass (right)	0.1	0.6	1.8	0.2	0.4	-0.0	1.2	1.3	1.2	-0.2	0.0
Arm fat mass (left)	0.1	0.3	1.7	-0.3	-0.3	-0.1	-1.3	-0.0	0.0	-0.5	-0.5
Number of self-reported non-cancer illnesses	0.2	0.3	2.2	-0.2	0.1	1.5	-0.1	0.3	0.3	0.1	-0.3
Average weekly champagne plus white wine intake	1.5	2.0	4.0	1.6	1.7	-0.1	1.2	1.8	2.0	1.0	1.1
Miserableness	1.8	3.2	6.1	-2.2	-2.5	-2.2	-0.3	-0.9	-1.5	-1.4	-2.2
Guilty feelings	1.1	1.7	3.8	-1.9	-1.6	-0.8	-0.9	-0.4	-0.8	-1.1	-1.9
Wears glasses or contact lenses	0.9	1.1	5.2	0.5	0.3	1.6	0.5	0.0	0.1	2.3	0.4
Ever taken oral contraceptive pill	2.2	2.5	4.3	2.1	2.1	-1.1	0.4	1.5	1.7	0.4	2.1
Hearing aid user	3.2	3.6	6.6	1.6	1.8	1.4	2.6	2.5	2.3	0.7	1.6
Mother’s age at death	0.2	0.2	0.9	0.4	0.6	-0.2	0.1	-0.3	0.1	1.0	0.3
Financial situation satisfaction	0.6	0.7	3.1	0.0	-0.5	-0.5	-1.1	-0.6	-0.7	-1.8	0.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.7	0.9	1.0	-0.9	0.6	1.0	1.3	0.9	0.6
Commuting to job workplace: Public transport	0.8	0.9	2.0	0.8	1.2	1.4	0.2	0.9	1.0	1.1	0.7
Eye problems/disorders: Glaucoma	0.3	0.3	1.5	-0.4	-0.3	0.6	1.2	0.4	0.3	0.3	-0.5
Medication: Blood pressure	0.2	0.4	2.4	-0.4	-0.6	1.5	-0.1	-0.3	-0.5	0.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.7	0.4	0.2	1.7	1.9	0.3	0.3	1.4	0.6
Supplements: Fish oil (including cod liver oil)	3.5	4.5	8.1	1.8	2.2	2.9	2.0	1.6	2.0	2.5	1.8
High cholesterol (Self-reported)	0.3	0.5	1.8	-1.2	-0.9	0.4	-0.2	0.3	-0.0	-0.2	-1.3
Medication: Bendroflumethiazide	1.5	2.3	4.1	1.9	1.6	1.8	0.8	0.6	0.8	1.9	2.0
Medication: Paracetamol	0.9	1.4	2.2	-1.1	-1.5	-1.2	-0.9	-1.3	-1.5	-0.0	-1.2
Medication: Lisinopril	0.3	0.4	1.8	-0.3	0.2	-0.4	0.4	1.3	1.0	-0.3	-0.4
Medication: Atorvastatin	0.9	1.2	3.5	1.4	1.1	0.1	-0.1	0.7	0.7	1.9	1.3
Illnesses of father: High blood pressure	1.1	1.4	2.9	0.9	1.0	-0.2	1.7	1.3	1.2	1.6	0.8
Alcohol drinker status: Never	0.8	0.9	3.3	0.5	0.2	1.2	1.2	-0.3	-0.4	1.8	0.8
Ever smoked	0.7	1.2	4.5	0.5	0.5	0.2	2.1	1.5	1.1	0.8	0.3
Basal metabolic rate	0.1	0.5	1.8	0.2	0.5	-0.3	1.3	1.1	1.0	0.1	0.0
Leg fat percentage (left)	0.1	0.5	2.8	0.1	0.2	-0.7	-1.7	-0.7	-0.3	-0.1	0.0
Arm fat-free mass (left)	0.1	0.6	2.6	0.5	0.6	-0.2	1.6	0.8	0.8	0.5	0.3
Number of operations (self-reported)	0.2	0.3	0.9	-0.8	-0.3	-0.0	0.2	0.1	0.0	-1.0	-0.7
Average weekly beer plus cider intake	0.5	0.8	1.3	0.8	1.2	-0.6	1.0	0.8	0.9	0.6	1.1
Irritability	1.1	1.9	3.9	-1.8	-1.9	-1.1	-0.3	-1.1	-1.3	-0.8	-2.0
Risk taking	0.2	0.3	1.5	-0.4	-0.1	-0.0	1.2	0.8	0.3	-0.3	-0.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.0	0.2	0.6	1.7	0.3	0.8	0.7	1.3	0.0
Fractured/broken bones in last 5 years	0.2	0.2	0.6	0.4	-0.2	0.8	0.3	0.8	0.5	0.4	0.2
Age started oral contraceptive pill	2.8	3.6	12.1	1.7	1.9	0.9	-0.1	1.8	2.0	3.5	1.3
Diastolic blood pressure, automated reading	0.2	0.5	2.1	-0.2	-0.2	-0.7	-1.5	-0.7	-0.5	-0.5	-0.3
Ever depressed for a whole week	1.5	1.8	4.2	-1.6	-1.4	0.8	-0.7	-1.1	-1.3	-2.1	-1.3
Unable to work because of sickness or disability	1.3	1.6	2.8	-1.2	-1.5	0.2	-1.7	-1.4	-1.4	-1.4	-0.9
Commuting to job workplace: Cycle	2.4	2.9	6.3	-2.5	-1.9	-1.5	0.2	-0.7	-1.4	-1.5	-2.5
Myopia	0.6	0.9	1.9	0.8	0.3	0.5	-1.2	-1.4	-0.9	0.9	1.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	4.7	-0.5	-0.8	-2.2	-0.2	-0.8	-0.7	-0.6	-0.6
Cholesterol lowering medication	0.7	1.0	3.3	-1.1	-1.0	1.8	0.6	0.6	0.2	-0.4	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.4	-0.9	-0.9	-0.6	-1.0	0.3	0.0	-0.2	-1.2
Pain experienced in last month	0.5	0.8	1.6	0.9	1.3	1.3	-0.9	0.5	0.9	0.3	0.9
Supplements: Calcium	0.4	0.5	2.7	0.2	0.6	0.1	-1.6	0.0	0.4	0.5	0.4
Basal cell carcinoma (self-reported)	0.5	0.6	1.7	-0.1	-0.2	0.5	-1.3	-1.2	-1.1	0.0	0.1
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.6	0.8	0.4	0.2	1.6	0.9	0.8	-0.4	0.9
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.2	-1.4	-1.3	-0.1	-0.8	-0.1	-0.4	0.4	-1.5
Heart disease (siblings)	2.9	3.6	6.2	1.9	2.2	2.5	1.5	1.2	1.5	2.3	1.8
Alcohol drinker status: Previous	2.9	3.3	4.8	1.8	2.0	0.8	1.9	1.9	2.2	1.9	1.8
Pack years of smoking	0.8	1.1	3.2	0.2	0.4	0.9	1.4	1.8	1.6	-0.5	0.1
Impedance of whole body	0.1	0.4	1.6	0.6	0.2	-0.4	-1.3	0.0	-0.0	0.2	0.8
Leg fat mass (left)	0.0	0.2	1.1	0.3	0.4	-0.2	-1.0	0.0	0.3	-0.0	0.1
Arm predicted mass (left)	0.1	0.5	2.0	0.3	0.5	-0.3	1.4	0.8	0.8	0.3	0.2