[Hub]/) : Traits : Heel T-Score : ← →

chr1:226,040,404-228,663,659

Best TWAS P=1.26e-14 · Best GWAS P=1.06e-14 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C1orf95	0.09	0.01	enet	12	0.05	1.3e-06	2.7	5.4	5.6e-08	-0.19	0.84	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SNAP47	0.23	0.19	lasso	7	0.19	5.7e-23	-5.4	5.9	3.2e-09	-0.20	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	CDC42BPA	0.10	0.05	lasso	5	0.02	3.6e-03	5.7	-5.5	3.5e-08	0.38	0.80	0.04	FALSE
4	GTEx	Adipose Visceral Omentum	CDC42BPA	0.08	0.12	lasso	2	0.07	1.5e-04	5.5	-5.5	4.6e-08	0.24	0.79	0.01	FALSE
5	GTEx	Artery Coronary	CDC42BPA	0.19	0.04	lasso	7	0.04	2.1e-02	5.8	-5.3	1.2e-07	0.26	0.26	0.05	FALSE
6	GTEx	Artery Tibial	CDC42BPA	0.36	0.21	enet	41	0.26	2.0e-20	5.7	-5.3	1.0e-07	0.26	1.00	0.00	FALSE
7	GTEx	Brain Cortex	SNAP47	0.21	0.05	lasso	9	0.04	2.2e-02	-5.3	6.1	8.7e-10	-0.25	0.04	0.72	FALSE
8	GTEx	Brain Cortex	CDC42BPA	0.25	0.00	enet	24	0.06	9.1e-03	5.8	-5.5	3.7e-08	0.28	0.22	0.13	FALSE
9	GTEx	Breast Mammary Tissue	CDC42BPA	0.15	0.04	enet	17	0.04	4.4e-03	5.7	-5.8	5.5e-09	0.25	0.68	0.02	FALSE
10	GTEx	Breast Mammary Tissue (Female)	CDC42BPA	0.12	-0.01	lasso	14	-0.01	6.4e-01	5.7	-6.3	2.7e-10	0.27	0.11	0.05	TRUE
11	GTEx	Cells EBV-transformed lymphocytes	JMJD4	0.13	0.06	lasso	4	0.03	2.9e-02	-4.7	-5.7	1.2e-08	0.12	0.07	0.24	FALSE
12	GTEx	Cells Transformed fibroblasts	SNAP47	0.17	0.12	enet	18	0.12	1.9e-09	-5.3	5.1	2.7e-07	-0.15	0.02	0.98	FALSE
13	GTEx	Cells Transformed fibroblasts	PSEN2	0.36	0.37	enet	24	0.40	1.1e-31	-7.0	7.0	2.2e-12	-0.90	0.09	0.91	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	CDC42BPA	0.27	0.09	lasso	13	0.14	1.0e-05	4.0	-5.3	9.2e-08	0.27	0.85	0.01	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	ADCK3	0.23	0.12	lasso	9	0.09	3.6e-04	-7.0	-7.3	3.2e-13	0.85	0.02	0.96	FALSE
16	GTEx	Heart Atrial Appendage	CDC42BPA	0.14	0.02	lasso	5	0.04	8.1e-03	6.0	-5.8	7.8e-09	0.23	0.43	0.08	FALSE
17	GTEx	Muscle Skeletal	SNAP47	0.09	0.08	lasso	10	0.08	7.7e-08	-5.4	5.5	3.5e-08	-0.18	0.01	0.99	FALSE
18	GTEx	Muscle Skeletal	CDC42BPA	0.12	0.06	enet	28	0.11	8.2e-11	-3.7	-6.4	2.0e-10	0.30	1.00	0.00	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	PSEN2	0.15	0.05	lasso	7	0.04	1.7e-03	-7.2	7.1	9.1e-13	-0.89	0.02	0.96	FALSE
20	GTEx	Skin Sun Exposed Lower leg	CDC42BPA	0.10	0.00	enet	32	0.02	1.3e-02	4.5	-5.9	3.2e-09	0.24	0.24	0.10	FALSE
21	GTEx	Skin Sun Exposed Lower leg	PSEN2	0.10	0.04	lasso	7	0.02	7.9e-03	6.2	5.9	3.5e-09	-0.71	0.08	0.76	FALSE
22	GTEx	Spleen	PSEN2	0.32	0.35	lasso	5	0.34	1.6e-09	-7.2	-7.3	2.2e-13	0.96	0.02	0.98	FALSE
23	GTEx	Testis	SNAP47	0.23	0.21	enet	15	0.21	7.5e-10	-5.3	6.0	2.4e-09	-0.15	0.02	0.98	TRUE
24	GTEx	Thyroid	PSEN2	0.11	0.04	enet	21	0.03	1.3e-03	-7.7	6.8	7.6e-12	-0.82	0.00	1.00	TRUE
25	GTEx	Whole Blood	ADCK3	0.14	0.17	lasso	5	0.17	3.4e-15	5.8	5.7	1.2e-08	-0.29	1.00	0.00	FALSE
26	METSIM	Adipose	CDC42BPA	0.06	0.01	bslmm	604	0.01	2.3e-03	4.0	-7.0	3.1e-12	0.40	0.16	0.54	FALSE
27	NTR	Blood	ADCK3	0.06	0.08	enet	9	0.08	2.5e-23	5.6	5.6	1.7e-08	-0.30	1.00	0.00	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	PSEN2	0.17	0.14	bslmm	500	0.15	2.8e-18	-7.2	6.6	5.1e-11	-0.80	0.01	0.99	TRUE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	PSEN2	0.14	0.06	lasso	4	0.07	5.4e-05	-5.7	6.3	2.2e-10	-0.73	0.33	0.44	FALSE
30	The Cancer Genome Atlas	Colon Adenocarcinoma	SNAP47	0.05	0.05	lasso	3	0.06	2.4e-04	-5.3	5.8	7.3e-09	-0.23	0.01	0.91	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PSEN2	0.02	0.02	blup	51	0.02	1.6e-03	-7.2	7.7	1.3e-14	-0.92	0.01	0.91	TRUE
32	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSEN2	0.08	0.00	blup	51	0.04	2.6e-03	-3.7	5.6	2.0e-08	-0.73	0.02	0.37	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAP47	0.08	0.06	blup	54	0.08	1.2e-09	-5.3	5.7	1.2e-08	-0.20	0.01	0.99	FALSE
34	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SNAP47	0.07	0.05	blup	54	0.05	2.9e-03	-5.3	5.6	2.1e-08	-0.20	0.01	0.76	FALSE
35	The Cancer Genome Atlas	Lung Adenocarcinoma	PSEN2	0.03	0.02	enet	8	0.03	2.8e-04	-6.9	6.0	1.6e-09	-0.84	0.01	0.93	TRUE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	CABC1	0.08	0.02	enet	6	0.05	6.6e-06	-5.7	-6.1	8.3e-10	0.58	0.38	0.44	FALSE
37	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CDC42BPA	0.42	0.00	blup	221	0.00	3.4e-01	-2.6	-5.6	2.1e-08	0.27	0.03	0.28	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	PSEN2	0.04	0.01	enet	7	0.02	4.1e-03	-7.7	7.2	4.7e-13	-0.94	0.00	0.99	TRUE
39	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PSEN2	0.17	0.05	blup	51	0.10	7.8e-04	-4.0	5.7	1.1e-08	-0.76	0.03	0.30	FALSE