[Hub]/) : Traits : Heel T-Score : ← →

chr17:36,211,659-37,644,854

Best TWAS P=1.07e-15 · Best GWAS P=1.09e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PCGF2	0.14	0.12	lasso	2	0.12	6.1e-10	-6.2	-6.9	4.4e-12	-0.28	0.99	0.00	FALSE
2	GTEx	Adipose Subcutaneous	PSMB3	0.11	0.01	enet	8	0.03	2.7e-03	6.4	5.7	1.0e-08	0.66	0.01	0.94	FALSE
3	GTEx	Adipose Subcutaneous	PIP4K2B	0.15	0.07	lasso	5	0.07	2.2e-06	8.0	7.7	1.5e-14	0.95	0.00	1.00	FALSE
4	GTEx	Adrenal Gland	PCGF2	0.34	0.09	lasso	6	0.11	8.5e-05	-6.2	-6.4	1.6e-10	-0.35	0.08	0.62	FALSE
5	GTEx	Artery Aorta	PCGF2	0.51	0.32	enet	27	0.37	1.2e-21	-6.2	-6.4	2.0e-10	-0.31	1.00	0.00	FALSE
6	GTEx	Artery Aorta	PSMB3	0.23	0.17	enet	26	0.22	2.1e-12	8.0	7.0	3.3e-12	0.84	0.00	1.00	FALSE
7	GTEx	Artery Tibial	PCGF2	0.38	0.27	lasso	8	0.31	4.3e-25	-6.2	-6.9	4.2e-12	-0.32	1.00	0.00	FALSE
8	GTEx	Artery Tibial	PSMB3	0.10	0.02	enet	12	0.03	1.2e-03	8.0	6.5	1.0e-10	0.73	0.00	0.99	FALSE
9	GTEx	Artery Tibial	PIP4K2B	0.37	0.16	enet	49	0.22	2.1e-17	8.0	6.3	3.1e-10	0.76	0.00	1.00	FALSE
10	GTEx	Cells Transformed fibroblasts	PCGF2	0.34	0.28	lasso	4	0.30	3.2e-23	-6.2	-5.7	1.1e-08	-0.21	1.00	0.00	FALSE
11	GTEx	Colon Transverse	PCGF2	0.29	0.21	lasso	5	0.20	6.2e-10	-6.2	-6.4	1.3e-10	-0.21	0.98	0.01	TRUE
12	GTEx	Esophagus Mucosa	PCGF2	0.32	0.24	lasso	7	0.23	1.8e-15	-6.2	-6.5	6.0e-11	-0.25	1.00	0.00	FALSE
13	GTEx	Esophagus Muscularis	PCGF2	0.21	0.15	lasso	8	0.13	3.3e-08	-6.2	-6.3	3.2e-10	-0.20	0.96	0.02	FALSE
14	GTEx	Heart Atrial Appendage	PCGF2	0.18	0.13	lasso	3	0.09	6.1e-05	-6.2	-6.1	9.8e-10	-0.18	0.29	0.07	FALSE
15	GTEx	Lung	PCGF2	0.25	0.17	lasso	7	0.17	4.8e-13	-6.2	-5.8	5.6e-09	-0.18	1.00	0.00	FALSE
16	GTEx	Nerve Tibial	PCGF2	0.20	0.07	lasso	4	0.13	3.1e-09	3.1	-5.7	1.5e-08	-0.30	0.71	0.12	TRUE
17	GTEx	Pancreas	PCGF2	0.29	0.12	lasso	5	0.07	5.3e-04	-6.2	-7.0	3.1e-12	-0.33	0.08	0.19	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	PCGF2	0.39	0.23	lasso	4	0.21	6.9e-12	-6.2	-6.3	3.8e-10	-0.20	1.00	0.00	FALSE
19	GTEx	Skin Sun Exposed Lower leg	PCGF2	0.36	0.30	lasso	7	0.32	1.3e-26	-6.2	-5.8	7.6e-09	-0.17	1.00	0.00	FALSE
20	GTEx	Testis	PSMB3	0.30	0.24	lasso	4	0.21	8.9e-10	8.0	8.0	1.1e-15	1.00	0.00	1.00	TRUE
21	METSIM	Adipose	PIP4K2B	0.06	0.01	blup	360	0.02	7.0e-04	5.1	5.2	2.3e-07	0.50	0.01	0.98	FALSE
22	NTR	Blood	PIP4K2B	0.02	0.01	lasso	3	0.01	6.4e-04	8.0	-7.2	5.5e-13	-0.97	0.00	0.99	FALSE
23	YFS	Blood	PCGF2	0.03	0.02	enet	7	0.03	2.1e-11	-6.2	-6.9	5.0e-12	-0.31	0.72	0.26	FALSE
24	YFS	Blood	PSMB3	0.14	0.11	enet	31	0.16	7.2e-49	7.9	6.5	6.3e-11	0.81	0.00	1.00	FALSE
25	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PCGF2	0.14	0.06	blup	35	0.11	1.1e-09	-4.0	-5.9	4.3e-09	-0.37	0.99	0.00	FALSE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PSMB3	0.04	0.00	blup	37	0.02	6.7e-03	5.1	6.7	1.8e-11	0.72	0.01	0.67	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	PCGF2	0.06	0.06	blup	37	0.05	4.4e-11	-6.2	-6.2	7.0e-10	-0.38	1.00	0.00	TRUE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	PCGF2	0.23	0.23	lasso	3	0.22	9.8e-13	-6.2	-6.7	2.4e-11	-0.24	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PIP4K2B	0.04	0.01	blup	56	0.03	6.3e-04	7.9	7.9	2.8e-15	0.83	0.00	0.93	TRUE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB3	0.14	0.05	blup	42	0.05	8.9e-07	7.9	5.7	9.7e-09	0.70	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PCGF2	0.11	0.00	blup	37	0.03	1.0e-02	4.8	-5.4	5.9e-08	-0.44	0.01	0.06	FALSE
32	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CISD3	0.11	0.06	blup	33	0.04	1.9e-03	-4.0	5.2	1.8e-07	0.25	0.12	0.11	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PCGF2	0.08	0.00	blup	37	0.01	3.8e-02	-2.4	-5.4	5.3e-08	-0.33	0.02	0.06	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PCGF2	0.28	0.16	lasso	4	0.13	3.4e-06	-6.2	-7.5	7.6e-14	-0.39	0.46	0.14	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	PCGF2	0.18	0.14	lasso	4	0.16	2.4e-16	-6.2	-7.6	2.9e-14	-0.39	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	PIP4K2B	0.05	0.04	blup	56	0.05	5.3e-06	7.6	7.4	1.0e-13	0.86	0.00	0.99	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMB3	0.11	0.07	blup	42	0.07	9.4e-08	8.0	5.6	2.6e-08	0.77	0.00	1.00	FALSE
38	The Cancer Genome Atlas	Soft Tissue Sarcoma	PCGF2	0.18	0.05	blup	36	0.11	7.3e-07	-2.8	-7.1	1.6e-12	-0.56	0.08	0.85	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	PCGF2	0.14	0.04	enet	8	0.16	6.8e-12	3.1	-6.4	1.5e-10	-0.41	0.90	0.03	FALSE
40	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PSMB3	0.12	0.09	lasso	3	0.06	3.0e-03	7.9	7.9	2.1e-15	0.97	0.00	0.94	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	PSMB3	0.05	0.06	lasso	1	0.05	2.4e-05	8.0	8.0	1.1e-15	1.00	0.00	1.00	FALSE