[Hub]/) : Traits : Heel T-Score : ← →

chr19:32,372,820-34,392,158

Best TWAS P=5.61e-223 · Best GWAS P=1.19e-214 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CEP89	0.10	0.01	blup	470	0.05	2.1e-06	-4.18	12.1	9.1e-34	0.34	0.05	0.92	FALSE
2	CommonMind	Brain Pre-frontal Cortex	GPATCH1	0.05	0.05	lasso	6	0.04	1.5e-05	9.61	10.2	1.2e-24	0.01	0.97	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	RHPN2	0.19	0.16	enet	18	0.18	5.7e-21	20.36	-27.2	2.0e-163	-0.68	1.00	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	WDR88	0.09	0.07	lasso	4	0.06	1.8e-07	16.44	17.2	3.9e-66	0.34	1.00	0.00	FALSE
5	GTEx	Adrenal Gland	PDCD5	0.15	0.02	lasso	6	0.01	1.2e-01	-2.52	-8.4	6.3e-17	-0.18	0.06	0.39	FALSE
6	GTEx	Artery Aorta	RHPN2	0.13	0.09	lasso	3	0.07	7.0e-05	27.72	-24.8	6.6e-136	-0.43	0.87	0.01	FALSE
7	GTEx	Artery Coronary	NUDT19	0.30	0.22	lasso	5	0.20	2.0e-07	4.14	-5.1	3.1e-07	-0.06	0.89	0.01	FALSE
8	GTEx	Artery Tibial	RHPN2	0.09	0.09	enet	17	0.11	5.1e-09	27.71	-26.0	2.0e-149	-0.50	0.99	0.00	FALSE
9	GTEx	Artery Tibial	C19orf40	0.13	0.10	lasso	2	0.09	2.8e-07	3.23	-7.0	2.6e-12	-0.15	0.94	0.00	FALSE
10	GTEx	Artery Tibial	CTD-2085J24.4	0.11	0.06	lasso	5	0.04	5.7e-04	-4.41	-5.2	1.5e-07	-0.18	0.32	0.03	FALSE
11	GTEx	Brain Caudate basal ganglia	RHPN2	0.20	-0.01	enet	18	0.03	4.8e-02	13.71	-17.5	1.6e-68	-0.52	0.06	0.38	TRUE
12	GTEx	Brain Cerebellar Hemisphere	PDCD5	0.33	-0.01	enet	39	0.00	4.4e-01	20.26	-8.4	3.1e-17	-0.16	0.05	0.06	FALSE
13	GTEx	Brain Cerebellar Hemisphere	CTD-2085J24.4	0.31	0.02	lasso	9	0.01	1.8e-01	-4.41	-5.5	4.8e-08	-0.16	0.07	0.06	FALSE
14	GTEx	Brain Frontal Cortex BA9	NUDT19	0.18	0.06	enet	25	0.12	5.0e-04	0.67	-7.2	6.4e-13	-0.14	0.22	0.10	FALSE
15	GTEx	Brain Frontal Cortex BA9	CTD-2538C1.2	0.45	0.02	enet	40	0.18	1.3e-05	-2.75	-9.0	1.6e-19	-0.10	0.21	0.05	FALSE
16	GTEx	Brain Hippocampus	PDCD5	0.36	0.04	enet	16	0.14	3.9e-04	-5.65	-5.2	1.5e-07	-0.18	0.14	0.05	FALSE
17	GTEx	Brain Hippocampus	RHPN2	0.22	-0.01	enet	9	0.00	3.3e-01	-7.00	-22.1	6.0e-108	-0.58	0.05	0.30	FALSE
18	GTEx	Breast Mammary Tissue	NUDT19	0.16	0.14	lasso	8	0.09	2.5e-05	4.02	-5.3	1.0e-07	-0.06	0.89	0.01	FALSE
19	GTEx	Breast Mammary Tissue (Male)	CEP89	0.10	0.06	lasso	2	0.06	1.4e-02	-4.41	11.3	1.5e-29	0.30	0.05	0.09	FALSE
20	GTEx	Breast Mammary Tissue (Male)	NUDT19	0.15	-0.01	lasso	2	-0.01	9.2e-01	6.34	-10.3	7.7e-25	-0.17	0.04	0.06	TRUE
21	GTEx	Cells Transformed fibroblasts	GPATCH1	0.08	0.12	lasso	3	0.12	5.3e-09	9.82	11.5	1.2e-30	0.00	1.00	0.00	FALSE
22	GTEx	Cells Transformed fibroblasts	RHPN2	0.08	0.00	enet	12	0.01	1.2e-01	9.82	-11.9	1.6e-32	-0.15	0.18	0.03	FALSE
23	GTEx	Colon Transverse	CEP89	0.19	0.01	enet	20	0.10	1.8e-05	-4.27	7.4	1.2e-13	0.19	0.10	0.06	FALSE
24	GTEx	Colon Transverse	NUDT19	0.46	0.25	enet	14	0.26	1.1e-12	6.98	-5.5	3.3e-08	-0.04	1.00	0.00	TRUE
25	GTEx	Colon Transverse	CTD-2538C1.2	0.16	0.02	enet	26	0.07	3.6e-04	-7.74	-8.3	8.9e-17	-0.12	0.42	0.03	FALSE
26	GTEx	Esophagus Gastroesophageal Junction	NUDT19	0.22	0.28	lasso	3	0.26	7.5e-10	4.80	-5.4	8.4e-08	-0.06	0.99	0.00	FALSE
27	GTEx	Esophagus Mucosa	GPATCH1	0.08	0.03	lasso	2	0.02	1.0e-02	2.26	9.7	2.4e-22	0.11	0.31	0.04	FALSE
28	GTEx	Esophagus Muscularis	PDCD5	0.14	0.13	lasso	4	0.12	7.1e-08	3.27	-8.4	4.0e-17	-0.20	0.91	0.02	FALSE
29	GTEx	Esophagus Muscularis	CEP89	0.15	0.05	lasso	5	0.08	1.1e-05	-5.38	10.4	3.5e-25	0.23	0.89	0.02	FALSE
30	GTEx	Esophagus Muscularis	RHPN2	0.20	0.08	enet	24	0.10	1.7e-06	20.26	-11.9	1.2e-32	-0.36	0.74	0.12	FALSE
31	GTEx	Heart Atrial Appendage	CTD-2538C1.2	0.31	0.37	lasso	2	0.36	8.1e-17	-5.09	-5.7	1.3e-08	-0.15	1.00	0.00	FALSE
32	GTEx	Heart Left Ventricle	PDCD5	0.18	0.01	enet	43	0.07	1.6e-04	-2.52	-5.5	2.9e-08	-0.16	0.09	0.06	FALSE
33	GTEx	Heart Left Ventricle	NUDT19	0.15	0.14	lasso	1	0.11	2.4e-06	6.34	-6.3	2.4e-10	-0.08	0.93	0.00	FALSE
34	GTEx	Heart Left Ventricle	CTD-2538C1.2	0.21	0.25	enet	9	0.21	2.5e-11	-5.09	-6.7	2.9e-11	-0.16	1.00	0.00	FALSE
35	GTEx	Lung	NUDT19	0.22	0.23	lasso	5	0.23	1.0e-17	4.80	-5.7	1.2e-08	-0.08	1.00	0.00	FALSE
36	GTEx	Lung	CTD-2085J24.4	0.14	0.02	enet	11	0.04	7.5e-04	-4.21	7.5	6.5e-14	0.03	0.41	0.04	FALSE
37	GTEx	Lung	CTD-2538C1.2	0.07	0.03	lasso	4	0.03	3.7e-03	3.23	-6.4	1.6e-10	-0.15	0.26	0.03	FALSE
38	GTEx	Muscle Skeletal	GPATCH1	0.07	0.03	enet	13	0.02	1.7e-03	9.82	13.7	1.2e-42	-0.02	0.28	0.02	FALSE
39	GTEx	Muscle Skeletal	RHPN2	0.06	0.05	lasso	3	0.05	1.6e-05	20.26	-25.2	2.3e-140	-0.51	0.66	0.22	FALSE
40	GTEx	Nerve Tibial	RHPN2	0.17	0.09	enet	19	0.12	1.5e-08	20.33	-21.5	1.3e-102	-0.48	0.98	0.00	FALSE
41	GTEx	Ovary	CTD-2085J24.4	0.20	0.00	lasso	5	0.00	2.7e-01	2.26	-5.5	4.2e-08	-0.07	0.08	0.05	TRUE
42	GTEx	Pituitary	NUDT19	0.27	0.03	lasso	3	0.08	4.4e-03	6.98	-6.8	8.9e-12	-0.11	0.12	0.08	TRUE
43	GTEx	Skin Not Sun Exposed Suprapubic	CEP89	0.21	0.05	lasso	5	0.07	1.4e-04	-4.41	6.0	1.6e-09	0.13	0.38	0.03	FALSE
44	GTEx	Skin Not Sun Exposed Suprapubic	NUDT19	0.15	0.11	lasso	3	0.12	3.1e-07	4.14	-5.5	4.4e-08	-0.06	0.97	0.00	FALSE
45	GTEx	Skin Sun Exposed Lower leg	RHPN2	0.15	0.07	enet	17	0.05	1.0e-04	-9.20	5.4	6.0e-08	0.12	0.56	0.02	FALSE
46	GTEx	Stomach	NUDT19	0.34	0.15	lasso	6	0.14	5.2e-07	4.02	-5.5	5.2e-08	-0.05	0.93	0.00	FALSE
47	GTEx	Stomach	CTD-2538C1.2	0.09	0.04	lasso	3	0.03	1.4e-02	-7.43	-7.6	3.4e-14	-0.17	0.35	0.04	FALSE
48	GTEx	Testis	GPATCH1	0.21	0.04	enet	27	0.08	2.8e-04	20.36	17.0	1.5e-64	0.32	0.54	0.08	FALSE
49	GTEx	Testis	CTD-2538C1.2	0.44	0.39	enet	24	0.36	5.7e-17	6.34	-8.2	1.6e-16	-0.11	1.00	0.00	FALSE
50	GTEx	Thyroid	RHPN2	0.18	0.02	enet	25	0.05	1.2e-04	16.97	-16.6	4.3e-62	-0.44	0.38	0.41	FALSE
51	GTEx	Thyroid	CTD-2085J24.4	0.09	0.09	lasso	2	0.07	3.1e-06	-7.00	-6.8	1.3e-11	-0.19	0.86	0.01	FALSE
52	GTEx	Uterus	GPATCH1	0.32	-0.01	enet	20	0.06	2.0e-02	-1.34	5.8	6.6e-09	-0.04	0.06	0.06	FALSE
53	GTEx	Whole Blood	ANKRD27	0.23	0.00	enet	44	0.06	3.3e-06	6.38	8.6	8.3e-18	0.15	0.18	0.04	FALSE
54	METSIM	Adipose	GPATCH1	0.12	0.12	lasso	11	0.11	9.7e-17	20.40	23.8	1.0e-125	0.49	1.00	0.00	FALSE
55	METSIM	Adipose	PDCD5	0.06	0.02	bslmm	393	0.01	9.9e-03	3.27	-7.1	1.3e-12	-0.24	0.57	0.15	FALSE
56	METSIM	Adipose	RHPN2	0.11	0.05	blup	478	0.11	1.5e-15	20.33	-15.1	1.3e-51	-0.32	1.00	0.00	FALSE
57	METSIM	Adipose	WDR88	0.07	0.06	lasso	7	0.08	2.1e-11	10.73	18.8	4.3e-79	0.46	0.99	0.01	FALSE
58	YFS	Blood	GPATCH1	0.05	0.01	blup	453	0.03	2.8e-09	18.32	16.2	7.4e-59	0.46	0.03	0.97	FALSE
59	YFS	Blood	LRP3	0.18	0.12	bslmm	431	0.16	7.1e-49	18.22	19.6	1.6e-85	0.38	1.00	0.00	FALSE
60	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	GPATCH1	0.03	0.01	blup	63	0.01	2.3e-02	26.36	23.9	1.4e-126	0.47	0.19	0.04	FALSE
61	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC7A9	0.09	0.03	blup	59	0.05	4.0e-05	0.19	5.5	2.8e-08	0.11	0.41	0.05	FALSE
62	The Cancer Genome Atlas	Breast Invasive Carcinoma	GPATCH1	0.08	0.07	blup	63	0.09	1.4e-17	9.66	7.1	1.4e-12	-0.02	1.00	0.00	FALSE
63	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUDT19	0.02	0.02	lasso	3	0.02	8.8e-05	6.34	-6.3	2.4e-10	-0.08	0.21	0.05	FALSE
64	The Cancer Genome Atlas	Breast Invasive Carcinoma	RHPN2	0.02	0.01	blup	66	0.02	4.2e-05	31.27	-28.7	5.8e-181	-0.78	0.00	0.99	FALSE
65	The Cancer Genome Atlas	Colon Adenocarcinoma	GPATCH1	0.06	0.07	blup	63	0.05	7.5e-04	20.36	22.1	8.9e-108	0.51	0.25	0.08	FALSE
66	The Cancer Genome Atlas	Colon Adenocarcinoma	RHPN2	0.12	0.01	blup	66	0.05	7.5e-04	20.26	-19.8	2.3e-87	-0.54	0.05	0.11	FALSE
67	The Cancer Genome Atlas	Glioblastoma Multiforme	GPATCH1	0.10	0.11	blup	63	0.10	6.5e-04	28.17	28.6	4.9e-180	0.59	0.05	0.53	FALSE
68	The Cancer Genome Atlas	Glioblastoma Multiforme	RHPN2	0.11	0.01	blup	65	0.00	2.5e-01	29.23	-31.9	5.6e-223	-0.79	0.01	0.81	TRUE
69	The Cancer Genome Atlas	Glioblastoma Multiforme	SLC7A9	0.36	0.13	blup	59	0.18	3.0e-06	-5.76	8.0	1.0e-15	0.18	0.11	0.19	FALSE
70	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GPATCH1	0.03	0.05	lasso	2	0.04	2.2e-05	20.33	21.1	6.3e-99	0.44	0.86	0.04	FALSE
71	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC7A9	0.05	0.01	blup	59	0.04	1.8e-05	-1.57	5.6	2.0e-08	0.14	0.26	0.33	FALSE
72	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPATCH1	0.07	0.11	lasso	6	0.10	2.3e-11	20.26	18.8	5.7e-79	0.30	1.00	0.00	FALSE
73	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RHPN2	0.05	0.01	blup	65	0.03	4.6e-04	30.08	-26.8	9.5e-158	-0.77	0.01	0.82	FALSE
74	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WDR88	0.03	0.01	lasso	3	0.02	1.7e-03	17.79	17.2	2.4e-66	0.34	0.12	0.05	FALSE
75	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RHPN2	0.21	0.02	blup	66	0.08	3.2e-05	20.36	-26.4	2.9e-153	-0.70	0.02	0.78	TRUE
76	The Cancer Genome Atlas	Brain Lower Grade Glioma	CCDC123	0.11	0.01	blup	73	0.06	8.0e-08	-0.86	7.5	9.0e-14	0.16	0.48	0.32	FALSE
77	The Cancer Genome Atlas	Brain Lower Grade Glioma	GPATCH1	0.05	0.05	enet	8	0.07	4.2e-08	9.82	16.4	3.8e-60	0.17	1.00	0.00	FALSE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	RHPN2	0.05	0.03	enet	11	0.05	3.5e-06	28.17	-29.5	4.7e-191	-0.74	0.14	0.85	FALSE
79	The Cancer Genome Atlas	Brain Lower Grade Glioma	TDRD12	0.03	0.01	blup	58	0.01	1.1e-02	-7.73	-7.9	3.8e-15	-0.17	0.28	0.02	FALSE
80	The Cancer Genome Atlas	Brain Lower Grade Glioma	WDR88	0.04	0.00	blup	66	0.02	1.2e-03	16.34	8.1	5.5e-16	0.12	0.07	0.03	TRUE
81	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	WDR88	0.08	0.05	enet	6	0.09	6.3e-05	13.61	19.5	1.0e-84	0.43	0.20	0.14	FALSE
82	The Cancer Genome Atlas	Lung Adenocarcinoma	GPATCH1	0.04	0.04	blup	63	0.05	2.9e-06	20.40	23.6	1.7e-123	0.40	0.98	0.00	FALSE
83	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	GPATCH1	0.03	0.01	blup	63	0.01	4.2e-02	9.82	11.7	7.3e-32	0.04	0.08	0.03	FALSE
84	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RHPN2	0.04	0.02	blup	65	0.02	5.1e-03	31.27	-22.0	4.7e-107	-0.66	0.00	0.96	FALSE
85	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC7A9	0.11	0.06	blup	59	0.09	9.0e-11	3.59	6.8	1.1e-11	0.18	0.98	0.01	FALSE
86	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	GPATCH1	0.07	0.05	blup	63	0.08	3.0e-04	9.61	21.9	3.4e-106	0.33	0.25	0.03	FALSE
87	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	GPATCH1	0.16	0.12	blup	63	0.13	8.4e-06	28.17	23.0	1.8e-117	0.36	0.78	0.04	FALSE
88	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NUDT19	0.08	0.04	enet	7	0.04	1.1e-02	6.34	-6.0	1.5e-09	-0.09	0.03	0.47	FALSE
89	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC123	0.10	0.07	blup	73	0.09	3.0e-09	-4.21	6.8	1.2e-11	0.21	1.00	0.00	FALSE
90	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPATCH1	0.27	0.20	lasso	4	0.24	2.0e-25	20.33	19.7	8.7e-87	0.30	1.00	0.00	TRUE
91	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC7A9	0.21	0.10	enet	25	0.20	1.1e-20	-4.21	7.2	7.1e-13	0.17	1.00	0.00	FALSE
92	The Cancer Genome Atlas	Prostate Adenocarcinoma	WDR88	0.05	0.03	blup	66	0.03	6.5e-04	16.44	12.2	5.4e-34	0.23	0.18	0.03	FALSE
93	The Cancer Genome Atlas	Soft Tissue Sarcoma	SLC7A9	0.14	0.00	blup	59	0.08	1.3e-05	3.08	5.8	5.8e-09	0.14	0.22	0.04	FALSE
94	The Cancer Genome Atlas	Stomach Adenocarcinoma	GPATCH1	0.05	0.04	blup	64	0.04	4.7e-04	19.47	21.4	9.4e-102	0.42	0.16	0.06	FALSE
95	The Cancer Genome Atlas	Stomach Adenocarcinoma	SLC7A10	0.08	0.00	blup	56	0.02	2.1e-02	16.44	-15.1	2.5e-51	-0.26	0.01	0.69	FALSE
96	The Cancer Genome Atlas	Thyroid Carcinoma	GPATCH1	0.29	0.28	blup	63	0.32	1.1e-31	20.35	9.7	3.7e-22	0.03	1.00	0.00	FALSE
97	The Cancer Genome Atlas	Thyroid Carcinoma	TDRD12	0.18	0.01	enet	21	0.03	2.5e-04	-1.02	-7.5	4.5e-14	-0.09	0.04	0.05	FALSE
98	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SLC7A9	0.20	0.04	blup	59	0.04	3.3e-02	-4.41	5.2	2.0e-07	0.19	0.04	0.04	TRUE