Hub : Genes

C19orf40

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.2290 0.0480 1.7e-09 0.113 NA 0.168 NA 0.028 1.6e-09 NA 1.2e-13 NA 2.1e-03
2 GTEx Adipose Visceral Omentum 0.1600 0.0620 4.6e-03 0.105 NA 0.009 NA -0.003 4.1e-06 NA 1.1e-01 NA 5.1e-01
3 GTEx Artery Aorta 0.1700 0.0690 6.9e-03 0.091 NA 0.094 NA 0.066 1.0e-05 NA 7.6e-06 NA 1.7e-04
4 GTEx Artery Tibial 0.1339 0.0446 2.4e-04 0.097 NA 0.070 NA 0.086 4.9e-08 NA 3.9e-06 NA 2.8e-07
5 GTEx Brain Caudate basal ganglia 0.1890 0.0830 4.6e-03 0.104 NA 0.053 NA 0.067 6.5e-04 NA 1.2e-02 NA 5.6e-03
6 GTEx Breast Mammary Tissue 0.2350 0.0740 1.1e-03 0.003 NA 0.040 NA 0.026 2.0e-01 NA 4.1e-03 NA 1.7e-02
7 GTEx Cells Transformed fibroblasts 0.2290 0.0540 1.5e-06 0.134 NA 0.139 NA 0.163 3.0e-10 NA 1.5e-10 NA 2.8e-12
8 GTEx Esophagus Gastroesophageal Junction 0.3880 0.0960 4.1e-04 0.010 NA 0.059 NA 0.039 1.4e-01 NA 3.7e-03 NA 1.5e-02
9 GTEx Esophagus Mucosa 0.1020 0.0400 6.6e-03 0.063 NA 0.060 NA 0.082 5.2e-05 NA 7.6e-05 NA 3.8e-06
10 GTEx Esophagus Muscularis 0.2060 0.0680 1.2e-03 0.091 NA 0.113 NA -0.001 3.5e-06 NA 2.3e-07 NA 3.9e-01
11 GTEx Lung 0.1191 0.0434 3.6e-03 0.041 NA 0.032 NA 0.029 4.3e-04 NA 1.6e-03 NA 2.8e-03
12 GTEx Nerve Tibial 0.2185 0.0590 8.3e-06 0.053 NA 0.066 NA 0.069 1.3e-04 NA 2.0e-05 NA 1.4e-05
13 GTEx Skin Not Sun Exposed Suprapubic 0.2170 0.0680 1.1e-03 0.093 NA 0.082 NA 0.102 8.8e-06 NA 2.9e-05 NA 3.2e-06
14 GTEx Skin Sun Exposed Lower leg 0.2280 0.0490 2.2e-08 0.084 NA 0.148 NA 0.184 1.8e-07 NA 2.8e-12 NA 4.0e-15
15 GTEx Testis 0.3010 0.0850 1.2e-04 0.154 NA 0.070 NA 0.153 2.5e-07 NA 4.8e-04 NA 2.5e-07
16 GTEx Thyroid 0.1910 0.0490 4.1e-06 0.116 NA 0.099 NA 0.022 3.5e-09 NA 5.1e-08 NA 8.2e-03
17 GTEx Whole Blood 0.1860 0.0420 7.0e-08 0.060 NA 0.109 NA 0.094 3.5e-06 NA 3.1e-10 NA 5.0e-09
18 METSIM Adipose 0.1813 0.0336 5.6e-17 0.125 0.140 0.150 0.15 0.153 2.8e-18 2.3e-20 8.0e-22 1e-21 3.3e-22
19 TCGA Bladder Urothelial Carcinoma 0.0930 0.0410 5.8e-04 0.049 0.035 0.031 NA 0.032 5.7e-05 5.6e-04 1.1e-03 NA 9.3e-04
20 TCGA Breast Invasive Carcinoma 0.0518 0.0196 1.1e-06 0.024 0.033 0.040 NA 0.031 8.6e-06 2.2e-07 9.0e-09 NA 4.2e-07
21 TCGA Head and Neck Squamous Cell Carcinoma 0.0534 0.0234 3.3e-04 0.056 0.038 0.059 NA 0.054 5.8e-07 4.1e-05 3.3e-07 NA 1.1e-06
22 TCGA Kidney Renal Clear Cell Carcinoma 0.1757 0.0706 1.5e-06 0.042 0.051 0.065 NA 0.072 1.4e-05 1.8e-06 8.2e-08 NA 1.8e-08
23 TCGA Brain Lower Grade Glioma 0.1080 0.0406 3.9e-06 0.049 0.064 0.060 NA 0.050 2.7e-06 8.8e-08 2.2e-07 NA 2.1e-06
24 TCGA Lung Adenocarcinoma 0.1387 0.0460 1.1e-07 0.062 0.076 0.080 NA 0.074 8.2e-08 3.6e-09 1.2e-09 NA 5.3e-09
25 TCGA Pancreatic Adenocarcinoma 0.1770 0.0680 2.7e-04 0.045 0.043 0.045 NA 0.063 5.7e-03 6.6e-03 5.5e-03 NA 1.3e-03
26 TCGA Pheochromocytoma and Paraganglioma 0.2050 0.0960 4.1e-03 0.029 0.051 0.059 NA 0.025 2.5e-02 4.4e-03 2.3e-03 NA 3.4e-02
27 TCGA Prostate Adenocarcinoma 0.0604 0.0271 2.9e-04 0.045 0.026 0.034 NA 0.032 1.5e-05 8.7e-04 1.8e-04 NA 2.7e-04
28 TCGA Stomach Adenocarcinoma 0.0980 0.0410 2.7e-04 0.068 0.059 0.060 NA 0.054 1.1e-05 4.1e-05 3.6e-05 NA 8.9e-05
29 TCGA Testicular Germ Cell Tumors 0.2180 0.0930 1.2e-03 0.086 0.057 0.065 NA 0.081 6.0e-04 4.5e-03 2.5e-03 NA 8.4e-04
30 TCGA Thyroid Carcinoma 0.1520 0.0460 5.2e-10 0.055 0.110 0.117 NA 0.131 4.1e-06 7.3e-11 2.0e-11 NA 9.6e-13

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Bipolar Disorder (2018) 1.1 1.7 7.1 -1.4 -1.5 -1.3 -1.4 -2.7 -0.7 -1.3 -0.9 -1.1 -1.2 -1.2 -1.9 -1.1 -0.7 0.7 -0.8 -0.6 -1.8 -1.1 -1.5 -1.2 -1.8 -1.5 -1.3 -1.3 0.0 -0.5 -1.0 -0.8 -1.5
Bipolar Disorder or Schizophrenia 1.4 3.4 10.3 -2.1 -2.5 -1.5 -2.2 -3.2 -1.9 -2.3 -1.9 -1.9 -1.9 -1.8 -2.5 -1.9 -1.2 1.5 -1.7 -0.7 -2.1 -1.1 -2.1 -1.6 -2.0 -2.0 -1.5 -1.7 0.0 -0.3 -1.5 -1.1 -2.3
Depressed Affect (Nagel 2018) 0.5 1.1 6.8 -0.6 -0.8 -0.7 -1.5 -2.6 -0.9 -1.6 -0.8 -1.2 -1.6 -1.0 -0.9 -1.4 -1.3 1.3 -0.9 0.5 -0.6 -0.0 -0.7 -0.3 -0.5 -0.3 -0.6 -0.7 -0.2 1.6 -0.2 0.2 -1.1
Depression (Nagel 2018) 2.5 3.8 7.3 -1.8 -2.2 -2.0 0.1 -0.5 -1.0 -1.4 -2.3 -2.5 -1.9 -0.9 -0.7 -2.5 -2.5 2.6 -2.7 -2.0 -2.1 -1.7 -2.1 -2.4 -1.8 -1.4 -2.0 -2.3 -1.0 -1.5 -2.2 -2.5 -2.2
Intelligence (Savage-Jansen 2018) 0.3 0.8 2.1 0.6 0.7 -0.3 1.4 -0.3 0.7 0.8 -0.7 1.4 1.2 0.7 0.6 1.1 0.1 -0.9 -0.2 -0.1 1.0 1.1 1.5 0.7 1.0 1.3 0.8 1.4 0.9 -0.4 0.5 0.6 1.2
Neuroticism (Nagel 2018) 0.6 1.5 3.6 -0.7 -1.5 -1.2 -1.9 -1.9 -1.1 -1.9 -1.5 -1.4 -1.9 -1.5 -0.7 -1.8 -1.9 1.7 -1.2 0.4 -0.7 -0.1 -0.8 -0.5 -0.5 -0.2 -0.8 -1.0 -0.2 1.2 -0.5 -0.1 -1.4
Schizophrenia (2018) 1.0 2.0 4.4 -1.6 -2.1 -1.1 -1.7 -2.0 -1.9 -1.9 -1.9 -1.6 -1.5 -1.4 -1.7 -1.6 -1.0 1.3 -1.4 -0.3 -1.2 -0.5 -1.4 -1.0 -1.2 -1.3 -0.8 -1.1 -1.9 -0.1 -1.1 -0.7 -1.7
Schizophrenia vs Biploar Disorder 0.3 0.4 2.0 -0.9 -0.7 -0.5 -0.9 0.0 -1.4 -1.2 -0.4 -0.6 -0.7 -0.9 -0.5 -0.6 -0.8 0.6 -0.3 0.8 -0.3 -0.1 -0.1 -0.6 -0.2 0.0 0.1 -0.9 0.0 0.9 -0.8 -0.4 -0.6
Worry (Nagel 2018) 1.0 2.1 6.5 -1.4 -2.4 -1.5 -2.0 -2.2 -1.7 -1.7 -1.1 -1.7 -1.7 -1.4 -0.5 -2.1 -2.6 1.9 -1.4 -0.3 -1.2 -0.9 -1.1 -1.0 -0.8 -0.5 -1.2 -1.5 -0.1 0.9 -1.0 -0.8 -1.5
Alzheimer’s Disease (in mother) 1.3 1.5 4.2 -1.1 -1.8 -1.9 -0.3 0.2 -0.9 -0.6 -1.8 -1.5 -1.2 -0.9 -0.0 -1.9 -1.6 1.8 -2.1 -1.6 -0.8 -1.2 -0.9 -1.2 -0.8 -0.3 -1.0 -1.2 0.2 0.3 -1.1 -1.3 -1.1
Alzheimer’s Disease (in father) 0.6 0.6 2.9 -0.4 -1.4 -0.4 0.1 -0.1 -0.1 -0.2 -1.6 -0.6 -0.8 -0.5 0.3 -1.1 -0.9 1.0 -0.4 -1.7 -0.6 -1.4 -0.3 -0.8 -0.7 -0.4 -0.2 -1.0 -0.5 0.3 -0.4 -0.6 -0.6
Alzheimer’s Disease (including proxy) 1.2 1.7 5.2 -1.0 -2.0 -1.7 -0.5 -0.6 -0.5 -0.6 -2.3 -1.5 -1.3 -1.0 -0.1 -2.1 -1.8 2.0 -1.8 -1.9 -0.7 -1.7 -0.7 -1.1 -0.9 -0.5 -0.7 -1.3 -0.3 0.9 -0.9 -0.9 -1.1
Crohns Disease (2017) 0.5 1.2 4.5 1.0 1.0 0.9 0.6 -0.6 0.4 0.8 0.1 1.8 1.4 0.9 1.0 1.6 1.1 -2.1 2.1 1.4 0.4 0.9 1.2 0.3 0.5 1.4 0.1 0.7 1.0 -1.2 0.8 -0.0 0.9
Irritable Bowel Disease (IBD) 0.7 1.6 4.6 0.8 1.0 1.3 0.9 -0.2 0.4 0.9 1.6 1.3 1.7 1.3 1.3 1.4 1.0 -1.9 1.5 1.9 0.8 1.3 1.6 0.8 1.3 2.1 0.7 1.1 1.8 -1.5 0.8 0.3 1.2
Ulcerative Colitis (UC) 0.8 1.5 6.5 0.6 0.7 1.1 1.1 0.3 0.1 0.8 2.5 0.2 1.5 1.4 1.0 0.9 0.9 -1.0 0.5 1.6 0.9 1.2 1.5 1.0 1.6 2.1 1.3 1.1 1.7 -1.5 0.3 0.5 1.0
Major Depression (MDD) 0.2 0.2 0.8 -0.3 -0.8 0.1 -0.9 -0.1 -0.5 -0.3 -0.9 0.3 -0.4 -0.8 -0.2 -0.6 -0.6 0.4 0.7 -0.2 -0.4 -0.6 -0.5 -0.2 -0.3 0.1 -0.2 -0.2 0.2 0.9 0.3 -0.1 -0.2
Reaction Time 0.6 1.1 3.0 -0.6 -0.7 -1.7 -1.3 -0.6 -1.7 -1.2 -1.1 -1.1 -1.2 -1.0 -1.1 -1.3 -1.0 1.2 -0.9 0.5 -0.8 -0.7 -1.3 -1.1 -1.2 -0.7 -0.4 -1.4 -1.2 0.4 -1.0 -0.9 -1.2
Verbal and Numeric Reasoning (VNR) 0.6 1.6 5.3 1.0 0.9 0.7 1.5 -0.9 1.2 0.7 -1.0 1.3 1.6 1.0 1.0 1.4 0.7 -1.2 -0.3 0.8 1.4 2.3 1.5 1.3 1.7 1.6 1.3 1.7 1.4 0.1 0.9 1.1 1.5
Breast Cancer 0.1 0.4 1.2 0.5 1.0 0.6 0.7 -0.7 -0.8 0.2 0.7 0.2 0.9 0.2 -0.2 0.8 1.1 -0.7 -0.0 0.2 0.3 0.8 -0.4 0.5 -0.1 -0.7 -0.7 0.5 -0.3 -0.9 0.1 0.3 0.3
Ovarian Cancer 0.4 0.5 1.9 0.7 0.7 0.8 0.7 -0.8 0.1 0.4 -0.5 0.2 0.6 0.4 -0.5 0.6 1.1 -0.8 0.9 0.6 0.8 0.1 0.3 1.1 0.4 -0.2 1.0 0.8 0.1 0.1 0.8 1.4 0.5
Prostate Cancer 0.4 0.5 1.9 0.2 -0.8 0.2 -1.3 0.3 0.5 -0.4 -0.7 -0.7 -0.6 -0.7 -0.3 -0.7 -0.4 0.3 0.0 -1.0 -0.7 -1.2 -0.7 -0.4 -1.0 -1.4 -1.1 -0.8 -0.6 0.6 -0.3 -0.2 -0.8
Age at First Birth 1.7 2.5 6.7 1.7 1.9 2.5 0.7 0.2 2.1 1.4 0.0 2.6 2.1 1.1 1.7 2.2 1.3 -2.2 1.7 1.7 1.2 1.5 1.7 1.2 1.3 1.5 1.1 1.4 0.9 0.6 1.4 0.9 1.8
Bipolar Disorder (2011) 0.4 0.4 4.6 -0.0 -0.4 -0.8 -0.8 -2.2 0.2 -0.3 -0.4 0.1 -0.7 -0.2 -0.9 -0.5 -0.5 0.0 -0.4 0.3 0.2 -0.8 0.0 -0.3 -0.8 -0.8 0.0 -0.4 0.0 0.0 -0.2 0.0 -0.6
Body Mass Index (BMI) (2010) 0.2 0.3 2.6 -0.5 -0.1 -0.8 -0.4 -1.6 -0.3 -0.5 -0.3 -0.0 -0.2 -0.6 -0.6 -0.4 -0.3 0.1 -0.4 -0.4 -0.5 -1.0 -0.3 -0.6 -0.9 -0.4 -0.3 -0.4 -0.9 -0.3 -0.5 -0.5 -0.5
Coronary Artery Disease (CAD) 0.3 0.3 1.7 0.4 -0.5 0.3 -0.9 0.5 0.2 -0.4 -1.3 0.5 -0.6 -0.5 -0.6 0.4 0.6 -1.0 1.0 0.3 -0.4 -0.3 -0.3 -0.0 -0.4 -0.8 -0.2 -0.1 0.0 1.2 0.0 0.2 -0.3
Crohns Disease (2012) 1.2 2.0 6.0 1.4 1.4 1.4 1.4 0.1 1.1 1.8 0.8 1.8 1.9 1.6 1.5 1.8 1.5 -1.8 2.4 1.0 1.0 1.4 0.8 0.8 1.1 1.4 0.0 1.2 2.0 -1.2 1.2 0.0 1.6
Mean Putamen Volume 0.1 0.1 0.8 0.1 0.2 0.7 -0.4 0.1 -0.3 0.1 -0.2 0.3 0.2 0.3 -0.3 0.5 0.3 -0.9 0.4 0.3 -0.2 0.3 -0.2 0.3 0.1 -0.4 -0.2 0.2 0.2 0.6 0.2 0.2 0.1
Fasting Glucose 0.6 0.7 2.6 -1.1 -0.6 -0.1 -0.8 -1.6 -0.0 -0.9 -1.0 -0.5 -0.5 -0.8 -1.1 -0.7 -0.5 0.2 -0.7 0.6 -1.1 -1.3 -0.5 -0.8 -1.2 -0.3 -0.3 -1.0 -0.9 0.2 -0.8 -0.7 -1.0
HbA1C 0.4 0.5 4.7 1.0 0.3 0.1 0.4 1.1 2.2 0.8 0.7 0.2 0.3 0.3 0.8 0.1 0.6 -0.1 0.4 -0.4 0.5 0.0 -0.3 0.6 0.4 -0.1 0.3 0.6 0.9 0.5 0.8 0.4 0.6
HDL Cholesterol 1.7 2.8 7.8 1.6 1.6 1.9 -0.0 0.4 0.4 1.0 0.8 2.8 1.3 0.2 0.7 1.9 1.1 -2.2 2.5 1.0 2.0 1.8 2.0 2.0 1.2 1.4 0.8 2.2 2.1 1.9 2.3 2.2 2.1
LDL Cholesterol 0.6 0.9 5.1 -0.1 0.3 -0.5 0.4 1.7 0.9 0.7 0.1 -0.3 -0.1 0.3 1.0 -0.5 -0.0 0.3 -0.5 -1.6 -0.7 -1.1 -1.4 -1.2 -0.8 -0.8 -1.2 -0.9 -0.1 -2.2 -0.7 -1.8 -0.5
Lupus 0.3 0.5 4.9 -0.2 -0.6 -0.2 -0.7 -2.2 -0.4 0.2 0.2 0.0 -0.3 -0.1 0.6 -0.5 -0.8 0.4 0.2 -0.8 0.3 -1.9 0.0 -0.1 -0.0 -0.4 -0.5 -0.5 0.3 1.2 0.3 -0.1 -0.0
Neuroticism (2016) 1.2 1.7 4.8 -0.7 -1.4 -2.1 -1.7 -1.1 -1.4 -1.8 -1.8 -1.2 -1.8 -1.8 -1.1 -1.5 -1.6 1.4 -2.2 -0.3 -0.6 -1.4 -0.3 -0.6 -0.8 -0.8 -0.5 -1.0 -1.2 1.1 -0.8 -0.0 -1.2
Primary Biliary Cirrhosis 1.4 2.0 6.8 -1.4 -1.4 -0.7 -2.5 -2.6 -1.5 -1.8 -0.6 -0.7 -1.8 -1.9 -1.2 -1.7 -2.4 1.1 -0.7 -1.0 -0.9 -1.1 -1.2 -1.4 -1.3 -0.7 -1.7 -1.2 -0.0 1.1 -1.0 -1.2 -1.5
Rheumatoid Arthritis 0.4 0.6 3.0 0.6 0.7 0.5 0.2 -0.9 1.7 0.4 -0.1 1.3 0.7 0.3 0.5 0.9 0.8 -1.0 0.8 1.0 0.6 1.0 0.5 0.5 0.5 0.8 0.7 0.9 0.8 0.5 0.6 0.5 0.8
Schizophrenia (2014) 1.3 2.8 8.6 -1.6 -2.0 -1.2 -2.5 -2.9 -2.2 -2.5 -2.1 -1.6 -1.9 -2.0 -2.2 -1.9 -1.4 1.3 -1.5 -0.6 -1.3 -0.6 -1.7 -1.0 -1.5 -1.7 -1.2 -1.2 0.0 0.8 -1.1 -0.4 -1.9
Triglycerides 1.6 2.6 6.7 -2.0 -1.1 -1.8 -2.1 -1.4 -1.7 -2.4 -0.6 -1.8 -2.1 -1.8 -2.5 -1.6 -1.0 1.1 -1.8 -0.0 -2.0 -0.2 -1.4 -1.2 -1.6 -1.5 -0.9 -1.4 -2.6 0.5 -1.4 -0.4 -2.0
Type 2 Diabetes (T2D) (2012) 3.2 3.7 6.0 -1.9 -1.4 -2.3 -1.7 0.7 -1.3 -1.5 -0.5 -2.2 -2.2 -1.8 -1.4 -2.3 -2.0 2.5 -2.4 -2.3 -1.9 -2.3 -2.3 -2.3 -2.4 -1.9 -2.2 -2.2 0.0 -1.0 -2.1 -2.1 -2.2
Ulcerative Colitis 1.3 1.9 12.3 0.9 1.4 1.3 0.8 -0.1 0.6 0.7 3.5 0.7 1.6 1.3 0.8 1.4 1.3 -1.1 1.0 2.0 1.0 2.3 1.0 1.3 1.8 1.9 0.0 1.4 1.7 0.0 0.7 0.0 1.3
Blood Eosinophil Count 0.0 0.3 1.5 -0.1 0.5 0.1 -0.5 0.4 -1.2 -0.3 -1.0 -0.3 -0.2 0.3 -0.8 0.0 0.0 0.1 -1.1 1.0 0.5 -0.4 0.8 0.5 0.5 0.5 0.4 -0.0 -0.3 1.0 0.2 0.6 -0.1
Blood Platelet Count 1.1 12.5 38.2 -4.8 -3.4 -2.6 -4.4 -3.5 -5.5 -5.0 -5.0 -2.5 -3.4 -4.0 -6.2 -2.5 -2.6 1.9 -3.3 -0.2 -3.7 -3.4 -2.2 -2.8 -3.9 -2.8 -2.7 -3.4 -3.5 1.1 -3.3 -1.7 -3.7
Blood Red Count 1.0 9.4 63.0 3.1 1.4 0.6 2.4 3.9 3.1 2.8 7.9 -1.2 1.2 4.1 3.6 1.1 3.1 -0.8 -0.2 2.8 2.9 3.2 2.6 3.5 4.6 2.5 4.2 2.1 2.5 0.3 2.8 3.4 2.2
Blood White Count 1.0 7.4 19.4 -3.1 -3.4 -3.5 -2.9 -0.2 -2.7 -3.1 -2.5 -2.9 -3.6 -2.6 -3.1 -3.3 -3.0 3.0 -4.4 -0.8 -2.8 -3.6 -2.1 -2.2 -2.2 -1.8 -1.6 -2.6 -2.6 0.9 -2.0 -1.6 -3.0
Heel T-Score 0.8 6.1 49.0 -1.6 -2.6 1.1 -7.0 -0.0 3.2 -1.4 -2.7 2.4 -1.6 -2.5 -0.4 -1.1 -3.1 -1.2 -1.9 -0.5 -1.8 -4.5 1.4 -2.0 -2.1 0.5 -0.2 -3.3 0.2 4.9 0.1 -1.3 -1.3
BMI 0.2 1.1 3.6 0.4 1.2 0.2 0.4 1.9 1.7 0.6 -0.9 1.5 0.7 0.7 0.8 1.4 1.2 -1.6 1.0 1.4 0.8 -0.2 1.1 0.7 0.9 1.4 1.5 1.0 0.3 -0.4 0.9 0.5 0.9
Height 0.1 1.1 9.2 1.1 1.0 0.2 -0.2 -3.0 -0.8 1.0 0.8 1.9 1.1 0.1 1.4 0.4 -0.5 -0.6 1.6 -0.2 1.1 -1.1 1.1 0.2 0.3 1.0 -0.2 0.9 1.4 0.4 0.6 -0.2 1.2
Waist Hip Ratio (WHR) 0.2 1.1 6.6 1.1 0.2 1.7 0.9 0.3 1.2 0.4 -2.6 0.9 1.0 0.6 1.6 1.1 0.5 -0.5 1.4 0.8 0.5 1.3 0.5 0.1 0.7 1.0 0.7 0.7 0.7 -1.8 0.0 -0.2 0.7
Systolic Blood Pressure 0.2 0.9 4.6 1.1 2.1 0.9 1.2 -0.9 0.1 0.9 -0.1 1.1 1.7 0.4 0.4 1.0 1.1 -1.1 1.1 -0.7 1.1 0.3 0.2 0.7 0.2 0.0 -0.5 1.4 1.4 -1.4 0.2 0.2 1.1
Smoking Status 0.4 0.9 3.6 0.8 0.7 0.7 1.3 1.0 0.1 1.1 0.4 -0.3 0.5 1.5 1.0 -0.0 0.6 0.3 1.2 -0.2 1.3 0.4 1.3 1.1 1.6 1.0 1.9 0.5 0.6 0.2 0.9 1.1 0.8
Allergy or Eczema 0.2 0.5 2.7 0.3 -1.5 -0.0 0.5 1.5 1.4 -0.1 -1.2 -0.5 -0.2 -0.3 0.7 -0.7 -0.9 0.9 -1.6 0.1 -0.3 0.6 -0.1 -0.2 0.1 0.7 0.4 -0.5 0.5 0.3 -0.1 -0.2 -0.1
Cardiovascular Disease 0.6 1.8 4.3 1.9 2.1 0.4 0.4 -0.3 0.9 0.7 -0.1 1.4 1.2 0.8 0.6 1.3 1.7 -1.7 1.2 1.9 1.7 0.3 1.8 1.8 1.5 1.5 1.6 1.6 1.3 1.1 1.3 1.8 1.5
Hypothyroidism (self reported) 0.1 0.3 2.8 0.2 -0.8 -0.5 -0.3 -1.7 0.6 0.1 1.1 0.3 0.1 -0.2 0.9 -0.1 -0.8 0.7 0.3 0.3 -0.1 -0.5 -0.3 -0.6 -0.3 0.3 -0.5 -0.2 0.0 -0.5 -0.2 -0.9 -0.1
Respiratory disease 0.3 0.6 3.3 0.8 -0.1 0.5 0.2 1.8 1.5 -0.4 -1.0 0.3 -0.1 -0.2 0.1 0.3 0.4 -0.2 -0.8 0.9 0.9 0.3 1.0 0.9 0.8 0.6 1.6 0.3 0.2 1.5 0.4 1.1 0.4
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.5 -0.1 0.2 -0.6 -0.9 -0.1 0.1 -0.6 0.2 -0.3 -0.8 -0.6 -1.0 -0.4 -0.5 -0.3 -0.7 0.1 -1.0 -1.2 -0.8 -0.2 -0.9 -1.2 -0.8 -0.5 -0.8 0.4 -0.1 0.0 -0.7
Lung FEV1/FVC ratio 0.1 0.5 1.8 0.2 -0.0 1.4 1.2 -0.4 0.1 0.8 0.6 -0.1 0.9 1.2 0.8 0.6 1.1 -0.3 1.2 1.2 0.2 1.1 0.3 0.5 0.7 0.8 0.5 0.3 0.4 -0.6 0.7 0.2 0.4
Lung FVC 0.6 2.9 5.9 -1.6 -1.4 -0.9 -0.7 -2.3 -1.6 -0.9 0.5 -2.2 -1.4 -0.7 -0.8 -2.1 -1.7 2.0 -0.8 -1.9 -1.9 -1.9 -2.1 -1.9 -2.0 -2.2 -2.4 -2.3 -1.2 -0.8 -1.5 -1.9 -2.1
Neuroticism 0.4 1.0 4.0 -0.3 -1.4 -0.6 -1.9 -2.0 -0.8 -1.6 -1.4 -0.6 -1.4 -1.4 -0.3 -1.2 -1.5 1.0 -0.8 0.6 -0.2 -0.3 0.0 -0.2 -0.1 0.4 -0.1 -0.4 0.1 1.7 -0.3 0.2 -0.8
Chronotype (morning person) 0.2 0.6 1.7 0.6 0.8 0.6 1.3 -0.5 0.0 0.5 0.7 0.0 0.8 0.7 -0.5 0.7 1.0 -0.9 0.7 -0.1 0.8 0.7 0.8 1.1 0.6 0.2 0.9 1.2 0.2 -0.6 0.4 1.3 0.7
Hair Pigment 0.0 0.2 0.9 -0.5 -0.7 -0.4 -0.0 -0.7 0.4 0.2 -0.2 -0.2 -0.5 0.2 0.2 -0.4 -0.8 0.4 -0.2 -0.2 0.0 0.1 -0.3 -0.1 0.4 0.5 0.4 0.0 0.9 0.2 0.2 -0.2 -0.1
Tanning 0.1 0.7 8.7 0.1 0.0 0.7 -1.1 -3.0 0.8 -0.4 1.1 0.3 -0.2 -0.0 -0.2 -0.1 -0.7 -0.2 1.2 0.2 0.3 0.6 -0.0 0.3 0.3 0.4 -0.2 0.4 -0.1 1.9 0.5 0.5 -0.1
Hand grip strength (left) 0.9 2.4 6.7 -1.2 -0.7 -1.1 -0.4 0.6 -1.8 -0.3 -0.5 -2.0 -1.2 -0.4 -0.1 -1.9 -1.6 2.2 -1.6 -2.6 -1.3 -1.9 -1.9 -1.8 -1.6 -1.4 -2.6 -1.7 0.3 -1.6 -1.6 -2.2 -1.6
Number of treatments/medications taken 0.2 0.4 3.8 0.1 0.5 -0.1 -0.7 -0.4 0.5 -1.2 -2.0 0.2 -0.2 -0.8 -1.0 0.1 0.0 -0.2 -0.0 1.0 -0.1 -0.9 0.5 -0.1 -0.4 0.3 0.7 -0.2 -0.7 0.2 -0.7 0.2 -0.3
Average weekly spirits intake 0.9 1.1 2.3 0.7 1.2 1.1 1.0 -0.0 1.2 1.1 0.2 1.4 1.2 0.8 1.1 1.4 0.8 -1.4 1.3 0.7 0.8 0.7 1.5 1.0 1.0 1.1 1.3 1.0 0.7 0.5 1.1 1.0 1.3
Sensitivity / hurt feelings 0.5 0.8 5.2 -1.0 -0.8 -0.9 -1.3 -1.0 -0.7 -1.5 -2.3 -0.6 -1.4 -1.1 -1.1 -0.8 -0.9 0.8 -0.7 0.3 -0.6 -0.3 -0.6 -0.6 -0.7 -0.5 -0.3 -0.7 -1.0 0.6 -0.5 -0.2 -1.0
Frequency of depressed mood in last 2 weeks 1.2 1.7 4.6 -1.1 -1.6 -1.7 -0.9 -1.1 -0.7 -1.3 -2.1 -1.1 -1.6 -1.3 -0.2 -1.6 -2.1 1.5 -1.1 -0.8 -1.2 -1.2 -1.3 -1.5 -1.2 -0.8 -1.0 -1.4 -1.1 -0.2 -1.1 -1.2 -1.4
Hearing difficulty/problems: Yes 1.2 1.8 5.7 0.6 1.1 1.1 -1.0 -1.7 0.7 -0.4 0.0 2.0 0.5 -0.3 -0.2 1.5 0.7 -1.9 1.8 2.4 0.7 1.6 1.8 1.3 0.9 1.5 1.4 1.2 0.3 2.4 1.4 1.8 1.0
Relative age of first facial hair 1.6 3.2 6.3 2.1 2.2 1.8 0.5 2.0 0.7 1.9 1.6 2.5 1.6 0.8 1.7 1.8 1.6 -2.0 2.1 1.2 2.1 2.3 1.6 1.8 1.6 1.7 1.2 2.3 2.5 0.5 2.1 1.5 2.3
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 2.7 0.8 0.9 1.1 0.9 -0.5 0.9 0.4 0.1 0.8 1.0 0.9 0.4 1.1 1.1 -1.4 1.4 1.6 0.8 0.7 1.2 1.2 1.1 1.1 1.5 1.0 0.5 0.4 1.1 1.2 0.9
Ever used hormone-replacement therapy (HRT) 6.8 8.7 15.3 3.0 2.8 3.9 1.8 0.2 3.1 2.9 2.3 2.9 3.0 2.8 2.6 3.2 3.1 -3.2 3.5 2.1 3.3 2.4 3.6 3.4 3.3 2.9 3.4 3.2 2.5 1.1 3.3 3.3 3.3
Ever had hysterectomy (womb removed) 0.3 0.3 1.4 0.6 0.6 0.7 0.4 -0.7 1.2 0.3 0.9 0.2 0.8 0.4 0.9 0.4 0.1 -0.5 0.8 0.2 0.3 0.1 0.5 0.5 0.5 0.5 1.1 0.5 -0.1 -0.4 0.2 0.4 0.4
Systolic blood pressure, automated reading 0.3 0.9 4.0 0.9 2.0 0.9 1.2 0.0 0.5 0.9 0.5 1.1 1.6 0.7 0.6 1.2 1.4 -1.2 0.9 -0.1 1.1 0.7 0.6 0.7 0.6 0.5 0.2 1.2 0.8 -1.2 0.3 0.3 1.2
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 2.3 0.2 0.1 0.0 -1.5 -1.0 0.4 -0.6 -0.4 0.5 -0.3 -0.7 -0.6 0.1 -0.1 -0.4 -0.0 0.3 -0.1 -1.1 0.1 -0.1 -0.6 -0.4 -0.2 -0.2 -0.6 0.8 0.0 0.2 -0.2
Angina 0.5 0.7 6.6 -0.3 0.3 -0.5 -1.3 -1.2 -0.9 -0.4 -1.8 1.2 -0.4 -0.5 -0.5 0.2 -0.3 -0.3 -0.6 0.6 0.6 0.3 0.9 0.2 0.3 0.6 0.8 -0.1 -0.3 2.6 0.6 0.7 0.3
Medication for hormone replacement therapy 3.3 3.7 7.5 2.3 1.9 2.4 2.1 1.1 2.7 2.2 2.1 1.4 1.9 2.6 2.5 1.9 1.5 -1.4 1.5 0.9 2.3 2.0 1.9 1.7 2.2 2.0 1.7 1.7 2.0 -0.6 1.9 1.3 2.0
Vitamin and mineral supplements 0.4 0.6 2.6 -0.8 -0.5 -1.1 -0.7 -1.6 -1.1 -0.5 -0.3 -0.8 -0.7 -0.4 -0.8 -0.7 -0.8 0.8 -1.3 -0.7 -0.4 -0.5 -0.7 -0.5 -0.6 -0.9 -0.9 -0.7 -0.5 0.4 -0.6 -0.4 -0.7
Supplements: Zinc 0.7 0.8 5.3 0.1 -1.1 -0.5 -0.4 2.3 1.4 0.1 0.7 -0.5 -0.9 -0.6 0.8 -1.1 -1.2 1.3 -0.6 -1.2 -0.3 -1.0 -0.8 -0.7 -0.6 -0.1 -0.8 -0.8 0.7 0.3 -0.1 -0.9 -0.5
Medication: Co-codamol 0.5 0.6 2.6 0.1 0.1 -1.1 -1.3 -1.4 1.0 -0.8 -1.0 0.7 -0.6 -1.1 -1.0 -0.0 -0.1 -0.4 -0.2 0.2 -0.3 -1.6 -0.2 -0.4 -0.9 -0.5 0.0 -0.0 -1.3 0.5 -0.2 -0.0 -0.3
Medication: Metformin 0.4 0.6 2.3 -0.4 -0.2 -1.4 -1.1 0.5 0.3 -0.4 -0.3 -0.4 -0.9 -0.7 -1.1 -0.7 -0.4 0.3 -0.7 -0.3 -0.9 -1.2 -1.0 -0.4 -1.0 -1.5 -1.3 -0.8 -0.1 0.4 -0.2 -0.3 -0.5
Diabetes (father) 0.6 0.8 6.6 -0.2 0.5 0.2 1.7 2.6 0.5 1.0 0.6 -0.6 0.8 0.9 0.7 0.1 0.2 0.2 -0.5 -1.1 -0.3 0.3 0.2 -0.4 0.1 0.6 0.2 -0.2 0.7 -2.3 -0.8 -0.8 0.1
Diabetes (mother) 0.5 0.7 3.6 0.5 0.1 0.5 -0.6 -1.2 -0.8 -0.3 -0.7 0.9 0.5 0.0 0.1 1.0 0.6 -0.9 1.2 1.9 0.2 1.1 1.0 0.9 0.8 0.7 0.8 0.5 -0.2 1.2 0.9 1.1 0.6
Severe depression (siblings) 3.5 3.9 7.8 2.8 2.4 1.7 1.4 0.8 1.6 2.1 1.5 1.7 2.0 2.1 2.1 2.0 2.2 -2.0 2.4 1.6 2.3 2.2 1.6 2.4 2.1 1.6 1.2 2.5 2.2 -0.2 2.3 2.0 2.3
Pack years adult smoking proportion 0.3 0.4 1.9 -0.3 -0.5 -0.3 -1.2 -0.4 0.3 -0.5 0.7 0.1 -0.3 -0.8 -1.1 0.1 0.7 -0.4 -0.3 0.0 -0.7 -1.0 -0.8 -0.0 -0.6 -1.4 -0.6 -0.2 -1.1 0.2 -0.1 0.0 -0.3
Impedance of leg (right) 0.1 0.5 2.9 0.4 -0.8 0.6 -0.8 -1.0 -1.6 -0.6 -1.7 0.1 -0.2 -0.7 -0.3 -0.4 -0.4 0.3 0.8 -0.1 0.7 1.2 0.1 0.4 0.3 0.1 -0.3 0.3 0.9 1.4 0.3 0.6 0.1
Leg fat-free mass (left) 0.2 1.2 3.2 0.7 1.6 0.4 1.0 0.3 0.9 1.7 1.3 1.2 1.2 1.4 1.8 1.1 0.4 -1.0 0.6 0.4 1.0 -0.2 1.3 0.8 1.1 1.6 1.1 1.2 1.7 -0.7 1.0 0.4 1.3
Trunk fat percentage 0.9 3.5 9.6 1.3 2.4 1.6 0.4 -0.0 1.9 0.8 -0.5 2.9 1.6 0.7 1.3 2.5 1.4 -2.6 2.8 3.1 2.0 1.4 2.4 1.6 1.6 2.8 2.4 2.0 1.2 0.7 1.8 1.7 2.0
Hand grip strength (right) 1.0 2.8 6.8 -1.6 -0.8 -1.2 -1.3 0.4 -2.6 -1.0 -0.7 -1.9 -1.6 -1.1 -1.0 -1.9 -1.8 2.0 -1.5 -2.0 -1.7 -2.0 -2.4 -1.8 -2.0 -2.0 -2.6 -1.6 -0.2 -0.9 -1.6 -1.9 -1.9
Townsend deprivation index at recruitment 0.3 0.4 2.2 -0.4 -1.0 -0.8 -0.8 -0.5 -0.0 -0.5 -0.8 -0.4 -1.0 -0.4 -0.9 -0.7 -0.3 0.4 0.0 -0.4 0.1 0.1 -0.5 0.3 -0.0 -0.7 -0.6 -0.0 -0.1 1.5 0.5 0.6 -0.4
Current tobacco smoking 0.3 0.5 2.0 -0.7 -1.1 -0.7 -1.0 0.2 -0.3 -0.4 -0.7 -0.9 -1.1 -0.5 -0.1 -1.2 -1.0 1.4 -0.8 -0.6 -0.5 -0.9 -0.8 -0.7 -0.3 -0.2 -0.0 -0.7 -0.7 0.3 -0.3 -0.6 -0.7
Average weekly fortified wine intake 1.9 2.3 5.2 -1.4 -0.8 -1.2 -1.1 0.2 -0.9 -1.0 -1.0 -1.4 -1.1 -1.1 -1.9 -1.3 -1.0 1.3 -1.0 -1.7 -1.9 -1.3 -2.0 -1.8 -2.3 -2.0 -2.2 -1.5 -1.6 -1.6 -1.9 -1.7 -1.7
Maternal smoking around birth 0.2 0.3 1.1 0.0 0.5 0.7 0.0 0.2 0.5 0.0 -0.5 0.6 0.8 0.5 0.1 1.0 1.1 -1.1 0.3 0.9 -0.1 0.8 0.5 0.2 0.3 0.7 0.3 0.1 0.3 -0.7 -0.0 0.0 0.2
Fed-up feelings 0.3 0.5 2.4 -0.0 -0.2 -0.6 -1.5 -0.9 -1.1 -1.4 -0.7 -0.5 -1.2 -1.1 -0.7 -0.6 -0.5 0.4 -0.4 1.0 -0.2 0.6 -0.4 0.1 -0.1 0.2 -0.1 -0.1 0.2 1.4 0.1 0.6 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 2.9 -0.5 -1.2 -1.0 0.0 0.9 -0.3 -0.7 -1.7 -1.2 -0.8 -0.3 -0.3 -1.0 -0.9 1.0 -1.4 -0.3 -0.9 -0.6 -0.8 -1.0 -0.7 -0.2 -0.3 -0.9 -0.9 -1.0 -1.0 -0.9 -1.0
Relative age voice broke 0.3 0.4 2.1 0.9 0.6 0.6 -0.1 0.6 -1.1 0.7 0.3 0.9 0.5 0.1 0.6 0.6 0.1 -0.7 0.5 0.2 0.6 1.2 0.4 0.6 0.4 0.6 0.3 0.9 1.4 -0.1 0.7 0.4 0.9
Taking other prescription medications 0.6 0.9 3.7 -0.5 -0.7 -1.0 -1.6 -0.2 -0.3 -1.5 -1.8 -0.1 -1.3 -1.5 -1.1 -0.8 -0.9 0.6 -0.6 0.2 -0.7 -1.9 -0.0 -0.8 -0.9 -0.1 0.0 -0.9 -0.8 1.1 -0.6 -0.3 -0.9
Age when periods started (menarche) 5.4 12.9 21.4 -4.1 -4.2 -3.2 -1.9 0.4 -2.4 -2.2 -1.9 -3.6 -3.0 -2.7 -2.8 -3.9 -3.5 4.0 -4.2 -4.0 -4.2 -4.6 -4.3 -4.5 -4.4 -3.6 -3.8 -4.3 -2.5 -2.6 -4.2 -4.6 -3.9
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.6 -0.0 0.0 -0.1 0.6 0.5 -0.0 0.2 -0.7 0.1 0.2 0.1 0.7 0.0 -0.3 0.2 -0.1 -0.6 -0.2 0.1 0.1 -0.2 -0.0 0.6 -0.0 -0.0 0.4 -0.5 -0.1 -0.4 0.1
Heel bone mineral density (BMD) T-score, automated (left) 2.2 4.9 23.7 -2.1 -2.2 -0.9 -4.9 -1.6 0.1 -2.0 -0.9 0.3 -2.2 -2.6 -2.0 -1.7 -2.8 0.8 -2.0 -1.5 -2.5 -3.5 -1.4 -2.7 -3.1 -2.1 -2.4 -3.0 -1.4 2.2 -1.5 -2.1 -2.0
Tinnitus: Yes, but not now, but have in the past 0.9 0.9 4.8 -0.9 -1.1 -0.4 -0.1 2.2 -1.5 -0.9 -1.4 -1.3 -1.2 -0.8 -0.4 -1.1 -0.8 1.1 -1.0 -0.8 -0.7 -0.1 -1.0 -0.7 -0.4 -0.8 -0.6 -1.2 -0.0 -0.0 -0.9 -0.7 -0.9
Qualifications: CSEs or equivalent 0.5 0.7 4.7 -0.2 0.4 0.0 1.1 1.3 -1.0 0.6 1.6 -1.2 0.6 0.8 0.3 -0.1 0.3 0.8 -1.3 -1.0 -0.2 -0.3 -0.4 -0.4 -0.1 -0.6 0.3 -0.7 -0.5 -2.2 -0.9 -0.6 -0.2
Serious illness, injury or assault to yourself 0.6 0.7 3.2 -0.7 -1.2 -0.9 -0.3 -0.5 0.0 -0.1 -1.7 -0.7 -0.7 -0.2 0.5 -1.3 -1.7 1.4 -1.3 -1.8 0.2 -1.3 -0.1 -0.5 0.1 0.3 -0.2 -0.2 0.5 -0.1 -0.3 -0.6 -0.3
High blood pressure 0.5 1.3 4.1 1.1 2.0 0.2 -0.0 -1.5 1.0 -0.3 -0.8 1.3 0.9 0.1 -0.3 1.0 1.2 -1.7 1.0 2.0 1.0 0.7 1.6 1.3 0.9 1.4 1.7 1.2 0.2 1.0 0.9 1.7 0.9
Hayfever, allergic rhinitis or eczema 0.2 0.4 1.9 0.5 -1.0 0.0 0.4 1.3 1.0 -0.4 -1.4 -0.1 0.1 -0.3 0.7 0.1 -0.5 0.3 -0.6 1.3 -0.4 1.0 0.1 -0.2 0.2 0.8 0.6 -0.5 0.2 -0.1 -0.4 -0.3 -0.1
Multivitamins +/- minerals 0.7 0.8 2.8 0.9 0.9 1.1 0.5 1.4 1.0 1.1 0.6 1.7 1.1 0.7 1.5 1.2 0.6 -0.9 0.7 0.3 0.4 0.5 0.8 0.3 0.7 1.3 0.4 1.0 1.2 -0.4 0.7 -0.1 1.1
Stomach or abdominal pain in last month 1.3 1.7 5.8 -1.4 -1.1 -1.5 -1.9 -0.4 -0.7 -2.1 -2.4 -0.9 -1.6 -2.1 -1.9 -1.4 -1.3 1.1 -1.2 -0.3 -1.1 -0.5 -1.0 -0.9 -1.2 -1.0 -0.6 -0.9 -1.3 0.6 -1.1 -0.3 -1.3
Supplements: Glucosamine 1.0 1.3 4.2 1.8 1.3 1.0 0.3 1.3 1.1 1.2 0.3 1.3 0.9 0.5 1.2 1.0 1.0 -1.3 2.1 0.4 1.2 -0.3 1.2 1.4 0.8 0.6 0.9 1.3 1.0 1.0 1.4 1.4 1.3
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 7.6 -1.6 -0.9 -0.8 -0.8 -2.8 -1.9 -1.6 -2.0 -0.3 -0.2 -1.0 -1.8 -0.3 -0.6 0.2 -0.8 0.0 -1.4 -0.0 -0.6 -0.9 -0.9 -0.4 -0.1 -0.6 -1.3 -0.6 -1.3 -0.6 -0.9
Medication: Atenolol 3.7 4.6 9.9 -2.8 -1.6 -3.0 -2.5 -1.5 -2.1 -2.8 -3.1 -1.2 -2.4 -2.8 -2.2 -2.1 -2.4 1.9 -2.9 -0.9 -2.1 -1.9 -1.7 -2.0 -2.2 -1.6 -2.2 -2.1 -1.5 1.2 -1.7 -1.5 -2.2
Medication: Levothyroxine sodium 0.3 0.4 1.8 -0.0 -0.7 -0.3 -0.9 -1.3 -0.0 -0.8 -0.1 -0.1 -0.5 -0.7 -0.7 -0.2 -0.1 0.3 0.4 0.3 -0.9 -0.8 -0.6 -0.9 -1.1 -0.5 -0.6 -0.9 -1.0 0.1 -0.6 -0.7 -0.8
Sitting height 0.2 1.2 8.2 0.9 0.4 0.7 0.9 -0.2 -0.3 1.8 0.9 1.3 1.3 1.2 2.2 0.5 -0.6 -0.1 0.1 -0.8 1.3 0.6 1.3 0.6 1.3 1.4 -0.0 1.1 2.9 -0.1 0.8 -0.1 1.5
Chronic bronchitis/emphysema (father) 0.7 0.9 2.5 0.7 1.0 1.3 -0.4 -0.2 1.2 0.2 0.4 1.4 0.7 -0.1 -0.0 1.4 1.0 -1.6 1.1 1.3 0.6 0.6 1.3 1.0 0.7 0.8 1.0 1.2 0.3 0.7 0.5 1.2 1.0
High blood pressure (mother) 0.3 0.4 1.5 1.2 0.7 1.2 1.2 0.7 -0.3 0.3 0.9 0.0 0.5 0.4 0.6 0.5 0.8 -0.4 1.1 0.6 0.1 0.9 -0.3 0.2 0.0 0.3 0.5 0.3 0.0 -1.1 0.1 0.2 0.1
Body mass index (BMI) 0.3 1.3 4.3 0.4 2.0 0.3 0.3 0.7 1.7 0.5 -0.1 1.6 0.8 0.7 0.6 1.7 1.1 -1.7 1.2 2.1 0.9 0.1 1.5 0.9 0.9 1.8 1.8 1.1 0.1 0.1 1.0 0.9 1.0
Impedance of leg (left) 0.2 1.1 5.2 -0.4 -1.4 0.1 -1.4 -1.7 -2.3 -1.5 -1.8 -0.4 -0.9 -1.6 -1.0 -1.0 -1.2 0.9 0.5 -0.5 -0.1 0.6 -0.8 -0.3 -0.6 -0.9 -1.1 -0.5 -0.0 1.5 -0.4 -0.0 -0.7
Leg predicted mass (left) 0.2 1.0 3.0 0.6 1.5 0.3 0.9 0.3 0.9 1.6 1.2 1.1 1.1 1.3 1.7 1.0 0.2 -0.8 0.4 0.3 1.0 -0.3 1.2 0.7 1.0 1.5 1.0 1.1 1.6 -0.7 0.9 0.3 1.2
Trunk fat mass 0.7 2.9 6.9 1.1 2.3 1.3 0.5 -0.1 1.9 1.0 -0.3 2.6 1.6 0.9 1.4 2.1 1.1 -2.2 2.3 2.4 1.9 0.9 2.3 1.5 1.6 2.6 2.2 1.9 1.5 0.5 1.6 1.4 1.9
Waist circumference 0.4 1.4 3.3 0.9 1.6 0.7 0.6 -0.1 1.8 0.7 -1.2 1.6 1.1 0.8 1.4 1.6 0.8 -1.4 1.6 1.5 1.2 0.3 1.4 0.7 1.0 1.8 1.7 1.2 0.6 -0.5 0.8 0.6 1.1
Number of incorrect matches in round 0.4 0.6 4.1 -0.3 -0.3 -0.1 -0.9 -1.4 -0.1 -1.4 -1.3 -0.1 -0.3 -0.7 -1.2 0.2 0.2 -0.5 0.5 0.9 -0.8 0.2 -0.8 -0.3 -0.7 -1.1 -0.1 -0.7 -2.0 0.7 -0.5 -0.1 -0.7
Past tobacco smoking 0.8 1.5 3.9 -1.2 -0.9 -0.9 -1.8 -1.7 -0.2 -1.4 -0.9 -0.2 -0.7 -1.4 -1.5 -0.5 -1.0 0.2 -1.6 0.0 -1.9 -1.4 -1.6 -1.6 -2.0 -0.7 -1.4 -0.9 -1.2 -0.7 -1.4 -1.5 -1.3
Alcohol usually taken with meals 0.3 0.5 2.7 0.1 -0.7 0.5 0.3 0.4 1.6 -0.2 -0.9 -0.4 -0.1 0.1 -1.3 0.3 0.9 -0.8 0.6 0.1 -0.7 -0.6 -0.7 0.2 -0.6 -1.1 -0.1 0.3 -1.3 -1.1 -0.1 0.3 -0.5
Nervous feelings 0.7 1.3 4.3 -0.6 -1.4 -0.6 -2.1 -1.5 -2.0 -1.7 -1.6 -0.6 -1.0 -1.7 -1.3 -0.7 -1.0 0.6 -0.9 0.2 -1.2 -0.3 -0.9 -0.8 -1.2 -1.4 -1.5 -1.1 -0.9 0.6 -0.9 -0.5 -1.1
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.5 8.1 -1.4 -1.9 -1.2 -1.2 0.4 -0.2 -1.2 -2.8 -0.5 -0.9 -1.6 -0.3 -1.1 -1.7 1.2 -1.0 -0.9 -1.4 -1.2 -1.0 -1.6 -1.3 -0.1 -0.9 -1.0 -0.8 -0.6 -1.6 -1.5 -1.1
Hearing difficulty/problems with background noise 0.5 0.8 3.5 0.2 0.7 0.8 0.3 -1.5 0.3 -0.6 -1.0 0.9 0.7 -0.4 -0.6 1.0 0.7 -1.2 1.0 1.1 0.5 1.0 1.3 0.9 0.5 1.1 1.9 0.9 -0.4 0.3 0.4 1.4 0.5
Hair/balding pattern: Pattern 2 0.3 0.4 2.7 -0.0 -0.7 -1.4 -0.6 -0.4 -0.1 0.0 0.6 -0.9 -0.6 -0.1 -0.1 -0.9 -0.7 1.3 -1.6 -1.0 -0.1 -0.2 -0.2 -0.6 -0.2 -0.1 -0.4 -0.4 0.4 -0.1 -0.8 -0.6 -0.2
Had menopause 5.1 6.4 12.3 2.8 2.2 2.9 1.1 0.3 2.5 1.6 0.9 2.3 2.1 1.8 1.6 2.7 3.0 -3.0 3.5 2.4 2.9 2.8 3.0 3.2 2.9 2.5 3.2 2.9 2.0 1.9 2.8 3.3 2.6
Had other major operations 0.4 0.5 2.8 0.5 0.2 -0.3 -0.5 0.3 1.1 0.1 -0.1 0.1 -0.4 0.0 0.5 -0.1 0.1 0.2 0.1 0.9 1.1 0.8 0.8 1.0 1.1 0.7 1.0 0.9 0.4 1.7 0.7 1.2 0.6
Forced vital capacity (FVC) 0.2 0.6 3.8 0.1 0.1 0.7 0.7 -0.5 -0.5 1.4 0.8 -0.0 0.5 0.9 1.9 -0.6 -1.0 0.7 0.3 -1.6 0.5 -0.2 -0.0 -0.1 0.3 0.1 -0.9 0.0 1.9 -0.3 0.4 -0.7 0.4
Heel bone mineral density (BMD) T-score, automated (right) 2.5 5.8 21.4 -2.8 -2.3 -1.0 -4.6 -1.8 0.1 -2.2 -1.4 0.2 -2.1 -2.8 -2.5 -1.8 -2.8 0.7 -2.2 -1.6 -2.9 -3.8 -1.8 -2.9 -3.4 -2.5 -2.7 -3.4 -1.7 2.1 -1.8 -2.5 -2.2
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 2.9 0.9 0.7 0.3 0.3 1.5 1.1 1.2 0.6 1.0 0.6 0.6 1.7 0.5 0.3 -0.4 0.5 -0.2 0.2 0.9 0.2 0.1 0.4 0.8 -0.3 0.3 1.3 -0.3 0.7 -0.3 0.7
Qualifications: None of the above 0.6 1.2 7.7 0.8 1.3 0.7 -1.4 0.6 -0.2 0.2 0.0 0.5 -0.1 0.2 -0.6 0.7 1.7 -1.2 2.4 1.7 1.1 -0.4 0.8 1.3 0.5 -0.3 0.7 0.4 -0.2 2.8 1.4 1.8 0.6
Financial difficulties in last 2 years 2.7 3.7 6.8 -2.5 -2.2 -2.3 -2.2 -0.4 -1.9 -2.1 -1.7 -2.2 -2.6 -1.9 -1.5 -2.5 -2.5 2.4 -2.2 -1.3 -1.7 -1.9 -1.9 -1.7 -1.6 -1.3 -1.3 -2.2 -1.0 0.9 -1.4 -1.3 -2.3
Mouth/teeth dental problems 0.5 0.7 3.8 -0.5 -0.3 -0.3 1.6 0.7 -0.2 0.7 1.8 -2.0 0.1 1.5 0.1 -0.5 -0.1 1.1 -0.8 -0.9 -0.2 -0.0 -0.1 -0.3 0.2 -0.0 0.3 -0.5 0.0 -1.8 -0.9 -0.4 -0.4
Heart attack 0.4 0.5 3.8 0.1 0.0 -0.3 -0.1 -0.5 -0.5 -0.3 -0.4 0.3 0.1 -0.1 0.3 0.2 -0.0 -0.1 -0.2 1.3 0.6 0.0 1.0 0.7 1.1 1.1 2.0 0.6 -0.5 1.0 0.4 1.0 0.5
Allergy 0.2 0.5 3.2 -0.3 0.7 0.5 0.6 -1.0 -0.6 1.0 1.8 0.1 0.5 0.8 0.2 -0.0 0.4 -0.2 0.7 -1.8 0.5 -0.3 0.2 0.2 0.2 -0.4 -0.9 0.7 0.6 -0.5 0.4 -0.0 0.4
Pain all over the body in last month 0.2 0.2 1.0 0.5 -0.3 -0.8 -0.2 -0.4 0.1 -0.3 -1.0 0.2 -0.2 -0.5 -0.0 -0.4 -0.7 0.2 0.5 -0.4 -0.1 -0.7 -0.2 -0.3 -0.3 -0.5 -0.1 -0.4 -0.3 0.7 -0.3 -0.2 -0.1
Diabetes (self-reported) 0.3 0.5 2.5 -0.1 0.3 -1.4 -1.6 -0.5 0.2 -0.9 -0.5 0.2 -0.8 -1.0 -1.2 -0.2 -0.3 -0.3 -0.2 0.9 -0.6 -0.9 -0.5 0.1 -0.5 -0.7 -0.3 -0.0 -0.6 1.0 0.1 0.4 -0.3
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 2.3 -0.8 -1.2 -0.7 0.1 0.6 -0.1 -1.0 -0.7 -1.1 -0.9 -0.8 -0.2 -1.0 -0.9 1.5 -1.1 -0.0 -0.9 0.2 -1.1 -0.9 -0.6 -0.1 -0.1 -0.8 -0.2 -0.3 -0.9 -0.9 -1.0
Medication: Ramipril 1.3 1.6 4.4 1.7 2.1 1.6 1.3 1.4 0.2 1.1 0.4 1.8 1.5 1.0 1.4 1.7 1.3 -1.7 1.8 1.2 1.0 1.6 1.0 0.9 0.9 1.3 0.8 1.1 1.0 -0.7 1.0 0.5 1.4
Medication: Simvastatin 1.6 2.3 7.1 1.6 2.5 1.5 0.8 1.1 0.7 0.8 -0.4 2.1 1.6 0.8 0.5 2.1 2.3 -2.7 1.9 1.9 1.2 1.0 1.7 1.6 1.0 1.4 1.8 1.6 0.4 0.3 1.5 1.8 1.5
Fluid intelligence score 0.4 0.7 4.0 0.5 0.2 0.7 1.6 0.2 0.8 0.8 0.1 1.3 1.4 0.3 1.2 1.1 0.0 -0.5 -0.3 -1.1 -0.1 1.0 0.1 -0.5 0.0 0.3 -0.8 0.4 1.0 -2.0 -0.4 -1.1 0.8
Illnesses of siblings 0.3 0.5 2.5 -0.8 -1.3 -0.8 -0.3 -1.6 0.6 -0.3 -0.6 -0.3 -0.3 -0.4 0.1 -0.7 -1.4 0.8 -0.5 -0.7 -0.3 -0.4 -0.3 -0.5 0.0 -0.3 -1.0 -0.5 0.3 0.1 -0.4 -0.8 -0.2
Neuroticism score 0.6 1.3 7.6 -0.6 -1.1 -0.3 -2.3 -2.8 -0.6 -2.2 -2.1 -0.5 -1.2 -1.7 -0.9 -0.9 -1.4 0.6 -0.5 1.3 -0.7 0.4 -0.1 -0.4 -0.5 0.4 -0.2 -0.6 -0.7 1.4 -0.5 0.2 -1.0
Weight 0.2 0.9 3.0 0.3 1.6 0.1 0.1 -0.3 1.0 0.8 -0.0 1.7 0.9 0.6 1.1 1.2 0.2 -1.3 1.1 1.0 1.0 -0.4 1.4 0.6 0.7 1.6 1.1 1.1 0.9 0.1 0.9 0.5 1.1
Impedance of arm (right) 0.1 0.3 2.2 0.4 -0.4 0.8 -0.7 -0.0 -0.4 -0.3 -1.5 0.9 0.1 -0.8 -0.0 0.2 -0.0 -0.3 0.7 0.4 0.5 1.4 -0.0 -0.0 -0.1 0.1 -0.2 -0.0 0.3 0.7 0.2 0.1 0.3
Arm fat percentage (right) 0.7 2.7 7.4 0.9 2.2 1.1 0.0 0.8 2.3 0.7 -0.9 2.5 1.1 0.7 0.9 2.3 1.4 -2.3 2.0 2.7 1.7 1.2 2.0 1.4 1.4 2.4 2.2 1.6 0.8 0.8 1.6 1.5 1.6
Trunk fat-free mass 0.1 0.4 2.3 0.0 0.7 -0.5 0.3 -0.7 0.1 1.0 0.8 0.3 0.4 0.8 1.1 -0.1 -0.5 0.1 -0.3 -1.0 0.5 -0.9 0.5 0.3 0.6 0.7 0.2 0.7 1.5 -0.1 0.4 -0.1 0.6
Hip circumference 0.3 1.1 2.8 0.6 1.6 0.1 0.6 -0.3 1.1 0.9 -0.4 1.4 1.1 0.8 1.2 1.3 0.7 -1.4 1.0 1.1 1.2 -0.6 1.5 0.9 0.8 1.7 1.7 1.2 0.6 -0.1 1.1 0.8 1.1
Time employed in main current job 0.9 1.0 2.9 -1.2 -1.1 -0.6 0.1 -0.2 0.0 -0.3 -0.6 -1.2 -0.5 -0.4 -0.5 -1.0 -0.8 1.2 -1.2 -1.3 -1.3 -1.7 -0.9 -1.3 -1.0 -1.1 -1.0 -1.4 -0.7 -1.5 -1.4 -1.5 -0.9
Alcohol intake versus 10 years previously 0.3 0.5 2.1 0.3 0.7 0.1 0.4 0.6 -0.2 1.5 0.7 0.9 0.8 1.0 1.1 0.2 0.0 -0.3 -0.1 -0.4 1.1 -0.7 0.7 0.4 0.6 1.1 0.5 0.8 1.3 -0.1 0.8 -0.1 0.9
Father’s age at death 0.5 0.7 3.0 1.1 1.0 1.7 0.8 1.3 0.4 0.6 1.7 0.3 0.9 0.7 0.8 0.8 0.5 -0.7 1.3 0.1 0.5 0.9 0.5 0.4 0.4 0.6 -0.2 0.7 1.2 -0.9 0.1 0.1 0.6
Worrier / anxious feelings 0.2 0.4 2.3 -0.1 -0.8 -0.7 -1.0 -1.3 -0.3 -0.6 -1.5 -0.0 -0.6 -0.5 0.1 -0.6 -1.0 0.5 -0.7 1.0 0.1 -0.4 0.5 -0.3 0.1 1.1 0.2 -0.4 0.2 0.8 0.1 -0.2 -0.3
Frequency of tiredness / lethargy in last 2 weeks 1.5 2.4 7.1 -1.6 -1.4 -2.2 -0.8 -0.7 -1.2 -1.9 -2.7 -2.0 -1.9 -1.4 -1.0 -1.9 -2.2 2.2 -2.2 -1.1 -1.0 -0.8 -1.5 -1.5 -1.1 -0.9 -0.9 -1.4 -1.1 -0.6 -1.8 -1.3 -1.8
Falls in the last year 1.3 1.8 7.6 -1.7 -1.4 -1.2 -1.9 -0.9 -0.5 -2.2 -2.7 -1.0 -1.5 -1.9 -2.1 -0.9 -1.0 0.9 -0.2 -0.1 -1.2 -0.9 -0.8 -0.9 -1.3 -1.0 0.1 -1.0 -1.9 0.8 -1.3 -0.2 -1.5
Hair/balding pattern: Pattern 3 0.4 0.6 3.1 -0.5 -0.9 -0.3 0.1 -0.7 -0.9 -0.4 0.4 -0.6 0.1 -0.1 -0.2 -0.2 -0.6 0.2 -0.5 0.1 -1.2 -0.5 -1.2 -1.0 -0.8 -0.6 -0.8 -0.9 -0.8 -1.8 -1.1 -1.4 -0.7
Number of live births 0.4 0.6 3.8 0.9 2.0 0.7 0.1 -0.6 0.0 0.1 -0.2 1.4 0.8 0.1 0.8 0.9 0.3 -1.2 1.7 0.3 0.8 0.6 0.7 0.2 0.3 0.6 -0.1 0.6 0.7 0.4 0.1 0.1 0.7
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 3.0 -0.4 -0.6 0.5 0.8 -0.5 -1.1 1.2 1.2 -0.7 0.1 0.9 1.6 -0.9 -1.1 1.1 -0.0 -1.5 -0.1 0.0 -0.6 -0.6 -0.0 -0.1 -1.4 -0.6 1.7 -1.0 -0.1 -1.3 -0.1
Pulse rate 1.8 3.1 6.2 -1.8 -1.2 -1.3 -1.6 -2.1 -1.9 -1.8 -1.3 -1.1 -1.1 -2.0 -1.5 -1.6 -1.4 1.5 -1.6 -1.7 -1.9 -2.4 -1.9 -2.0 -2.3 -2.2 -2.5 -1.9 -1.8 -0.4 -1.9 -2.0 -1.7
Happiness 0.7 0.8 1.5 -0.8 -1.0 -1.1 -1.0 -1.0 -1.2 -0.4 -0.6 -0.8 -0.8 -0.7 -0.5 -1.0 -0.8 1.0 -0.8 -1.2 -0.9 -1.1 -1.1 -0.9 -1.1 -1.1 -1.2 -1.0 -0.3 0.4 -0.8 -0.8 -0.9
Noisy workplace 0.2 0.2 2.7 0.1 0.1 0.1 -0.8 -1.6 -1.0 -0.6 -0.2 -0.2 -0.1 -0.2 -0.8 -0.1 -0.1 -0.3 0.5 0.4 -0.3 0.0 0.2 0.2 -0.2 0.1 0.4 0.1 -0.2 0.1 -0.1 0.5 -0.2
Qualifications: A levels/AS levels or equivalent 2.2 5.0 10.8 2.4 0.9 2.2 2.8 0.9 3.3 2.6 1.8 2.2 2.7 2.4 3.0 2.2 1.5 -2.0 2.3 0.7 1.8 2.8 2.1 1.8 2.4 2.8 1.8 2.7 2.8 -1.6 1.9 1.1 2.5
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.8 1.0 0.4 0.5 1.7 0.5 1.3 0.9 1.6 0.2 1.1 0.9 1.0 0.7 0.9 -0.6 0.5 0.4 0.4 0.6 0.3 0.4 0.6 0.0 0.5 0.4 0.1 -1.1 0.2 0.0 0.7
Mouth/teeth dental problems: Dentures 0.3 0.5 2.9 0.1 0.9 0.5 -1.3 -1.1 0.5 -0.7 -1.7 1.6 0.4 -1.0 -0.3 0.6 0.2 -1.3 1.0 0.7 0.1 0.0 0.0 -0.1 -0.5 0.1 -0.2 0.1 -0.5 0.7 0.3 0.1 0.2
Asthma 0.2 0.4 1.6 0.2 -0.3 -0.1 -0.1 1.2 1.2 -0.4 -1.0 -0.2 -0.3 -0.2 -0.1 0.1 0.3 0.1 -1.2 0.7 0.6 0.0 0.7 0.5 0.5 0.5 1.3 0.1 -0.0 0.8 0.1 0.8 0.2
Medication: Ibuprofen (e.g. Nurofen) 1.4 1.8 3.2 -1.1 -1.6 -1.4 -0.6 1.0 -0.8 -1.1 0.0 -1.4 -1.3 -1.0 -0.3 -1.5 -1.8 1.6 -1.6 -1.1 -1.6 -1.7 -0.9 -1.7 -1.2 -1.0 -1.2 -1.8 -1.4 -0.9 -1.7 -1.8 -1.4
Medication: Cholesterol lowering 2.3 3.5 7.2 1.8 2.1 1.2 0.7 0.7 1.4 1.3 -0.3 2.3 1.5 1.2 1.1 1.9 2.1 -2.2 1.8 2.7 2.1 2.1 2.5 2.1 2.3 2.6 2.5 2.2 1.4 1.2 2.0 2.2 2.2
Depression (self-reported) 0.8 1.0 2.7 -1.0 -1.0 -0.8 -0.6 -0.2 0.3 -0.4 -1.1 -1.0 -0.9 -0.3 -0.1 -1.0 -1.6 1.1 -0.7 -0.9 -1.1 -1.2 -1.2 -1.4 -1.1 -0.7 -1.2 -1.2 -0.6 -0.8 -0.9 -1.5 -1.2
Medication: Lansoprazole 2.0 2.2 4.5 -1.6 -1.5 -1.5 -1.0 -1.2 0.4 -1.7 -1.0 -1.0 -1.2 -1.8 -0.9 -1.6 -1.5 1.5 -1.0 -1.9 -1.5 -2.1 -1.6 -1.8 -1.7 -1.6 -2.0 -1.5 -1.2 -1.0 -1.7 -1.8 -1.6
Prospective memory result 0.4 0.5 1.9 0.5 1.1 0.6 0.2 -0.4 -0.1 -0.1 0.8 1.0 0.8 0.2 -0.2 1.2 1.1 -1.4 1.0 1.2 0.3 0.7 0.6 0.7 0.5 0.2 0.9 0.4 -0.2 0.2 0.4 0.7 0.6
Lung cancer (father) 1.3 1.5 4.5 1.5 1.3 2.0 1.2 1.2 1.4 1.4 1.1 1.2 1.4 1.0 1.4 1.5 2.1 -1.5 2.0 0.9 1.0 0.4 0.9 1.0 0.8 0.8 0.8 1.2 0.7 -0.7 1.0 0.6 1.2
Illnesses of mother 0.5 0.6 3.1 -0.0 0.6 0.9 0.5 0.2 1.8 1.4 1.0 1.1 0.8 1.1 0.8 0.7 0.4 -0.7 0.4 -0.7 0.9 -0.1 0.4 0.5 0.7 0.3 -0.1 0.8 1.2 -0.2 0.9 0.1 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.3 6.6 -1.5 -1.7 -0.6 0.1 -1.2 -2.0 0.2 0.2 -1.9 -0.9 0.0 0.6 -2.0 -2.1 2.4 -0.9 -2.6 -1.2 -1.2 -1.6 -1.7 -1.0 -1.0 -2.6 -1.6 0.9 -1.4 -1.2 -2.3 -1.2
Pulse wave Arterial Stiffness index 0.8 1.0 7.0 0.0 -0.3 -1.1 -2.6 -0.2 -0.2 -1.7 0.2 0.8 -1.1 -2.1 -1.4 -0.1 -0.4 -0.5 -0.0 1.2 -0.7 -0.8 -0.6 -0.2 -1.0 -0.8 -1.2 -0.1 -0.7 1.7 0.0 0.1 -0.5
Impedance of arm (left) 0.3 1.6 6.0 1.5 0.6 2.0 0.5 0.1 0.8 0.7 -0.8 1.7 1.2 0.3 1.1 1.3 0.8 -1.2 1.8 1.4 1.7 2.5 1.3 1.1 1.3 1.5 1.1 1.2 1.5 0.6 1.2 1.1 1.4
Arm fat mass (right) 0.5 2.1 5.1 0.8 2.0 0.8 0.3 0.1 1.9 1.0 -0.3 2.1 1.2 1.0 1.3 1.9 1.2 -1.9 1.7 2.0 1.6 0.6 1.9 1.3 1.4 2.3 2.0 1.6 1.1 0.6 1.5 1.3 1.6
Trunk predicted mass 0.1 0.4 2.5 0.0 0.6 -0.5 0.3 -0.7 0.1 1.0 0.8 0.3 0.4 0.9 1.1 -0.1 -0.5 0.1 -0.4 -1.0 0.5 -0.9 0.5 0.3 0.6 0.8 0.2 0.7 1.6 -0.1 0.4 -0.1 0.6
Standing height 0.1 0.8 5.6 0.3 -0.1 -0.1 0.1 -1.8 -0.8 1.1 0.2 0.8 0.6 0.1 1.6 -0.5 -1.5 0.5 0.1 -2.0 0.7 -0.6 0.3 -0.0 0.3 0.4 -0.8 0.7 2.4 -0.1 0.3 -0.6 0.8
Length of working week for main job 0.3 0.3 2.6 -0.2 -0.0 0.2 0.3 1.6 -0.3 0.3 1.1 -1.0 -0.5 0.4 -0.2 -0.5 -0.1 0.5 0.1 -0.5 0.3 -0.3 0.1 0.3 0.2 -0.6 0.5 -0.2 -0.5 0.7 0.0 0.6 -0.2
Exposure to tobacco smoke at home 1.0 1.2 2.8 -0.5 -1.7 -1.2 -0.9 -0.9 -0.3 -1.1 -0.1 -1.2 -1.6 -1.4 -0.5 -1.6 -1.0 1.3 -0.7 -0.9 -1.0 -1.3 -1.4 -1.0 -1.3 -1.1 -0.7 -0.9 -1.4 0.1 -0.7 -0.6 -1.3
Breastfed as a baby 0.5 0.6 2.1 -1.1 -1.2 -0.6 -0.6 -1.4 0.1 -0.6 -1.0 -1.0 -0.9 -0.4 -1.3 -1.1 -1.0 0.9 -0.6 -1.1 -0.6 -1.3 -0.5 -0.2 -0.7 -0.4 -0.3 -0.3 -0.2 0.3 -0.3 0.2 -0.8
Tense / ‘highly strung’ 0.5 0.8 3.8 -0.5 -1.4 -0.4 -1.9 -0.7 -0.8 -1.0 -0.2 -0.3 -1.2 -1.5 0.2 -1.2 -1.7 1.0 -0.4 -0.3 -0.5 -0.7 -0.3 -0.4 -0.4 0.2 -0.8 -0.4 0.9 1.8 -0.1 -0.2 -0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.6 4.9 -1.2 -1.7 -0.8 -2.1 -1.6 0.6 -1.6 -1.1 -0.6 -1.6 -1.5 -0.7 -1.4 -2.2 1.2 -1.0 0.0 -1.6 0.1 -1.0 -1.4 -1.2 -0.0 -1.4 -1.3 -0.3 0.8 -0.8 -1.1 -1.4
Hair/balding pattern: Pattern 4 0.2 0.4 1.8 0.2 0.7 0.3 0.4 0.5 0.9 0.3 -1.4 0.8 0.1 0.1 0.2 0.4 0.1 -0.8 0.9 0.1 0.8 0.6 0.6 0.7 0.5 0.5 0.5 1.0 0.2 0.5 0.9 0.9 0.5
Birth weight of first child 0.2 0.3 2.0 0.1 0.4 0.3 1.3 0.9 -0.4 0.4 0.2 -0.3 0.6 0.8 0.4 0.4 0.8 0.0 -0.3 0.5 0.1 0.4 0.2 -0.0 0.5 0.2 0.5 0.0 -0.2 -1.4 -0.4 -0.2 0.1
Peak expiratory flow (PEF) 0.3 0.6 3.5 0.1 0.1 1.1 1.0 1.9 -0.7 1.1 0.9 -0.6 0.2 0.8 1.4 -0.5 -0.3 0.4 0.3 -1.3 0.1 0.0 -0.2 -0.2 0.1 -0.2 -0.8 -0.5 1.4 -0.9 0.0 -0.6 0.0
Pulse wave reflection index 0.3 0.4 2.1 0.2 -1.2 -1.4 -1.3 0.1 0.1 -0.5 0.5 -0.2 -1.2 -0.8 -0.5 -0.6 -0.4 0.4 -0.4 0.3 -0.2 -0.1 -0.4 0.2 -0.1 -0.3 -0.6 0.2 0.0 1.4 0.6 0.5 -0.3
Ever highly irritable/argumentative for 2 days 0.6 0.7 2.4 -0.1 -0.6 0.1 -0.6 -0.1 -0.4 -0.5 -0.5 -1.4 -0.8 -0.0 -0.2 -0.7 0.2 0.6 -0.3 -0.2 -1.6 -0.7 -1.5 -0.7 -1.0 -1.5 -1.1 -1.4 -1.0 -0.1 -0.6 -0.7 -1.2
Loud music exposure frequency 0.6 0.6 4.6 0.5 0.0 -0.0 -0.5 -1.1 -0.2 0.7 -0.4 0.2 -0.1 0.4 0.5 -0.2 -0.4 -0.0 0.0 -0.3 1.1 0.8 0.6 1.1 0.9 0.3 0.4 0.6 1.2 2.1 1.4 1.3 0.6
Qualifications: O levels/GCSEs or equivalent 1.7 2.8 9.5 1.5 0.6 1.1 3.1 0.7 1.8 2.0 2.0 1.1 2.1 2.0 3.1 1.3 0.9 -0.7 0.2 0.0 1.0 2.4 1.3 0.8 2.0 2.4 1.3 1.5 2.1 -2.3 0.8 -0.1 1.6
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 5.0 1.0 0.0 0.9 -0.7 0.7 0.7 0.1 -0.5 2.2 0.1 -1.1 0.7 0.9 -0.0 -1.4 1.0 0.9 -0.2 0.4 -0.2 0.1 -0.2 0.1 -0.8 0.7 0.7 1.4 1.1 -0.0 0.7
Blood clot in the leg (DVT) 0.3 0.4 3.6 -0.6 -0.5 -1.0 -0.1 -0.5 -1.9 -0.1 -0.5 -0.6 -0.3 -0.1 0.1 -0.5 -0.4 0.7 -0.2 -0.3 -0.8 -0.3 -0.9 -0.8 -0.4 -0.2 -0.3 -0.5 -0.3 -1.0 -0.8 -0.9 -0.4
Medication: Paracetamol 0.2 0.3 1.0 -0.0 -0.0 -0.2 -1.0 0.2 -0.7 -0.9 -0.9 0.1 -0.3 -0.7 -0.4 -0.1 -0.3 -0.0 -0.3 0.6 -0.3 -0.8 -0.2 -0.4 -0.5 -0.5 -0.5 -0.4 -0.8 0.2 -0.5 -0.4 -0.4
Headache pain in last month 0.7 1.2 3.3 1.6 1.4 0.3 0.8 1.3 0.8 1.0 0.6 1.1 1.0 1.1 1.8 1.0 0.1 -0.6 0.7 1.1 1.4 0.9 1.4 0.9 1.5 1.7 1.4 1.2 1.3 0.3 0.7 0.6 1.4
Medication for cholesterol, blood pressure or diabetes 2.7 4.5 9.5 -2.1 -3.0 -1.4 -0.7 0.9 -1.5 -1.2 0.5 -2.9 -2.0 -1.2 -0.9 -2.4 -2.3 2.9 -2.4 -3.1 -2.1 -2.0 -2.7 -2.3 -2.2 -2.9 -2.6 -2.7 -1.4 -0.9 -2.1 -2.4 -2.4
Glaucoma (self-reported) 0.8 0.9 4.9 -0.1 -0.5 -0.8 1.1 0.5 -0.8 0.5 -0.6 -1.3 0.1 0.7 0.7 -0.9 -0.5 1.1 -1.3 -1.3 -0.6 -1.7 -0.6 -1.1 -0.7 -0.1 0.1 -1.0 -0.4 -2.2 -1.1 -1.5 -0.6
Gout (self-reported) 0.2 0.3 1.2 0.7 0.5 0.2 0.8 0.0 1.0 0.5 -0.7 1.1 1.1 0.0 0.3 0.6 0.7 -0.9 -0.2 -0.4 0.1 -0.3 0.5 0.1 -0.0 0.2 -0.0 0.5 0.1 -0.7 0.1 -0.1 0.6
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 4.0 0.1 -0.3 -0.4 -1.0 -2.0 0.2 -0.4 0.6 0.7 -0.1 -0.6 -0.1 0.2 -0.5 0.3 0.6 0.6 -0.3 -0.5 -0.2 -0.6 -0.6 -0.1 -0.7 -0.2 -0.5 0.4 -0.2 -0.6 -0.1
Medication: Amlodipine 0.8 1.1 3.6 0.9 1.7 1.2 -0.2 -0.5 1.6 0.0 0.5 1.1 0.7 0.3 -0.1 1.4 1.3 -1.7 1.2 1.9 0.7 0.9 0.9 1.0 0.6 1.1 1.6 1.3 -0.1 0.1 0.6 1.3 0.7
Medication: Ventolin 100micrograms inhaler 0.5 0.6 4.5 0.3 0.2 -0.2 -0.5 1.6 1.1 -0.2 0.0 -0.1 -0.1 -0.1 0.1 -0.0 0.2 0.1 -0.6 1.0 0.9 0.0 1.0 0.8 0.9 1.3 2.1 0.2 0.4 1.6 0.3 1.1 0.4
Birth weight 0.7 1.4 3.7 0.6 0.8 1.0 1.9 -0.9 0.7 1.1 1.6 0.3 1.6 1.8 1.6 1.0 0.7 -0.6 1.2 1.0 1.4 1.2 1.4 0.9 1.7 1.6 1.9 1.1 0.9 -1.1 0.4 0.5 1.1
Chronic bronchitis/emphysema (mother) 1.1 1.3 3.5 -1.5 -0.8 -1.2 0.1 0.1 -0.5 -1.2 -1.1 -1.4 -0.6 -0.8 -1.2 -0.8 -0.6 1.1 -1.2 -0.9 -1.7 -0.6 -1.2 -1.3 -1.3 -1.4 -0.5 -1.4 -1.6 -1.0 -1.9 -1.2 -1.3
High blood pressure (siblings) 0.5 0.7 8.4 0.9 1.5 1.1 0.3 2.9 -0.6 0.6 0.2 0.6 0.3 0.3 0.4 0.6 1.1 -0.7 0.9 0.5 0.7 0.1 0.2 0.6 -0.0 0.5 0.7 0.6 0.9 0.1 0.6 0.6 0.4
Forced vital capacity (FVC), Best measure 0.4 1.4 6.8 -1.1 -1.1 -0.5 -0.1 -1.6 -1.3 0.4 -0.1 -1.1 -0.5 0.1 0.9 -1.6 -2.0 1.9 -0.5 -2.6 -0.5 -1.3 -1.0 -1.2 -0.6 -0.8 -2.0 -1.0 1.2 -0.6 -0.7 -1.7 -0.7
Body fat percentage 0.7 2.8 8.5 1.0 2.2 1.3 0.1 0.2 1.8 0.5 -0.9 2.5 1.3 0.6 1.0 2.2 1.2 -2.3 2.4 2.9 1.8 1.1 2.2 1.4 1.4 2.5 2.3 1.7 0.9 0.9 1.5 1.6 1.6
Leg fat percentage (right) 0.4 1.5 4.9 0.5 1.7 0.6 -0.6 -0.1 1.0 -0.1 -1.3 1.7 0.6 0.2 0.2 1.4 0.8 -1.7 1.9 2.2 1.3 0.5 1.7 1.2 0.9 1.7 1.9 1.2 0.3 1.3 1.1 1.5 0.9
Arm fat-free mass (right) 0.1 0.4 2.0 0.1 0.7 -0.4 0.5 -0.4 0.3 0.8 1.1 0.4 0.4 0.7 1.2 0.1 -0.6 0.1 -0.1 -0.4 0.5 -0.9 0.8 0.2 0.6 1.2 0.4 0.8 1.4 -0.3 0.3 -0.1 0.6
Exposure to tobacco smoke outside home 0.2 0.2 1.6 -0.0 -0.9 0.1 -0.2 -1.3 -0.3 -0.2 -0.5 -0.2 -0.3 -0.2 -0.0 -0.4 -0.1 -0.0 0.3 -0.5 0.0 -0.7 0.2 0.4 0.2 -0.6 0.6 -0.1 -0.6 1.0 0.4 0.7 -0.1
Comparative body size at age 10 1.7 4.6 6.7 2.5 2.5 1.9 2.4 0.3 2.4 2.5 1.6 2.2 2.4 2.4 2.0 2.2 2.2 -2.6 2.2 1.1 2.6 1.4 2.2 2.3 2.2 1.9 2.3 2.5 1.8 -0.1 2.4 2.0 2.4
Number of full brothers 0.2 0.2 0.9 0.9 0.7 0.0 -0.2 -0.7 0.2 0.1 0.3 0.1 -0.0 0.1 -0.7 0.2 0.7 -0.4 0.8 0.5 0.2 -0.1 -0.4 0.3 -0.5 -0.6 -0.0 0.0 -0.6 0.3 0.4 0.5 0.0
Worry too long after embarrassment 1.2 2.1 5.1 1.6 1.5 1.4 1.2 0.6 1.4 1.0 0.7 1.4 1.4 1.2 1.9 1.6 1.1 -1.1 1.1 1.7 1.8 1.6 2.2 1.2 1.9 2.1 1.8 1.3 1.1 0.1 1.1 1.1 1.6
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.0 5.9 -1.3 -2.2 -1.7 -1.3 -2.4 -1.0 -0.9 -0.9 -1.0 -1.5 -1.3 -0.2 -2.0 -2.4 1.9 -1.2 -1.7 -1.2 -0.9 -1.5 -1.3 -1.0 -1.0 -1.9 -1.3 0.7 0.8 -0.8 -1.3 -1.1
Wheeze or whistling in the chest in last year 0.5 0.9 3.3 0.1 0.2 0.4 -1.0 -0.4 0.3 -1.4 -1.0 0.9 0.1 -1.0 -0.7 0.9 0.1 -1.0 0.1 1.8 0.9 0.4 1.6 1.1 0.8 0.7 1.7 0.8 -0.7 1.3 0.3 1.7 0.6
Number of children fathered 2.0 2.2 6.4 1.0 0.8 0.6 -0.3 -2.5 1.5 0.5 0.9 1.4 0.5 0.4 0.2 0.9 1.2 -1.2 2.0 2.1 1.7 1.2 1.5 1.9 1.4 1.6 2.1 1.8 0.3 2.4 2.2 2.4 1.2
Reason for reducing amount of alcohol drunk: Health precaution 2.7 3.2 7.1 1.8 1.3 1.9 1.4 0.3 1.1 1.4 2.2 2.0 2.1 1.3 2.1 2.1 1.3 -1.5 2.7 2.1 1.8 1.9 2.1 1.6 2.0 2.4 1.9 2.1 1.7 -0.3 1.3 1.1 2.1
Age at first live birth 1.0 1.7 6.5 -0.9 -0.7 -0.9 -0.0 0.2 0.2 -0.3 -1.7 -0.0 0.1 -0.6 -0.3 -0.4 -0.8 0.4 -1.2 -1.5 -1.9 -1.5 -1.5 -2.1 -2.1 -1.0 -1.9 -1.4 -1.1 -2.6 -1.7 -2.5 -1.1
Pulse wave peak to peak time 0.9 1.1 6.4 0.2 0.6 1.3 2.5 0.0 0.5 1.8 -0.2 -0.3 1.3 2.0 1.5 0.4 0.5 0.2 0.3 -1.2 0.9 0.9 0.8 0.4 1.1 0.9 1.3 0.4 0.9 -1.5 0.1 0.0 0.7
Health satisfaction 2.5 3.3 6.2 -1.6 -1.6 -2.2 -1.9 0.5 -2.0 -1.7 -1.8 -1.3 -1.9 -1.9 -1.0 -1.9 -2.0 1.7 -2.3 -1.1 -1.8 -2.5 -1.7 -2.1 -2.0 -1.8 -2.0 -2.3 -1.7 0.4 -1.8 -2.0 -1.8
Shortness of breath walking on level ground 0.4 0.5 2.3 1.0 1.5 0.4 0.4 0.5 0.0 -0.2 0.4 1.0 0.5 -0.1 0.1 1.0 1.0 -1.1 1.0 1.5 0.5 1.2 0.1 0.6 0.4 0.3 0.5 0.7 -0.0 0.3 0.4 0.5 0.6
Qualifications: College or University degree 0.2 0.7 3.2 0.4 -0.7 0.3 1.5 0.8 1.8 1.0 -0.2 1.0 1.0 0.4 0.7 0.6 0.1 -0.9 0.0 -1.5 0.0 0.4 0.5 0.1 -0.1 0.3 -0.7 1.0 0.8 -1.5 0.5 -0.1 0.6
Eye problems/disorders: None of the above 3.0 3.4 7.7 1.9 1.7 2.3 1.4 1.7 1.6 1.5 1.6 1.5 1.5 1.3 1.7 1.8 1.7 -1.5 1.9 1.4 2.0 2.8 2.5 2.1 2.2 2.2 1.8 2.2 1.6 0.4 1.8 2.2 2.0
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.7 -0.3 -0.1 0.0 -0.9 0.2 -1.3 -0.7 -1.3 -0.5 -0.5 -0.5 -1.3 -0.0 0.1 0.0 -0.3 -0.1 0.0 -0.4 0.6 0.5 0.1 -0.8 0.2 -0.1 -1.1 1.3 -0.0 1.0 -0.2
Emphysema/chronic bronchitis 0.3 0.3 1.2 0.3 0.4 0.3 -0.3 0.9 0.7 -0.0 0.5 0.2 0.0 0.0 -0.3 0.3 0.3 -0.4 -0.1 0.5 0.7 -0.4 0.8 0.9 0.5 0.2 1.1 0.4 -0.1 0.7 0.7 1.1 0.4
Medication for pain relief, constipation, heartburn 0.5 0.8 2.3 1.2 0.5 0.9 0.9 0.9 1.0 1.5 0.8 0.7 0.9 1.2 1.1 0.7 0.7 -0.6 0.3 -0.1 0.9 1.5 0.3 0.8 0.8 0.6 0.3 1.0 1.3 0.0 1.1 0.6 0.9
Neck or shoulder pain in last month 0.2 0.4 2.4 0.6 0.2 -0.4 -1.4 0.1 -0.0 -0.6 -1.6 1.1 -0.5 -1.3 -0.1 -0.0 -0.6 -0.2 0.4 0.0 0.2 0.1 -0.3 -0.2 -0.5 -0.1 -0.3 0.4 0.2 0.8 0.3 0.0 0.1
Medication: Blood pressure 2.0 3.5 7.5 1.8 2.5 1.4 0.3 -1.6 1.2 0.8 -0.8 2.2 1.4 0.8 0.5 1.7 1.7 -2.3 1.9 2.5 2.2 1.7 2.5 2.4 1.8 2.4 2.3 2.4 1.3 1.9 2.2 2.7 2.0
Angina (self-reported) 0.6 0.8 7.7 -0.2 0.4 -0.4 -1.5 -1.4 -0.8 -0.5 -1.9 1.2 -0.4 -0.5 -0.6 0.2 -0.2 -0.5 -0.4 0.8 0.6 0.3 1.0 0.3 0.3 0.6 0.9 -0.0 -0.5 2.8 0.7 0.9 0.3
Migraine (self-reported) 0.2 0.3 1.0 0.6 0.8 0.7 -0.3 -0.2 -0.5 0.3 1.0 0.0 0.5 0.7 0.7 0.5 0.2 0.1 0.7 0.7 0.5 1.0 0.5 0.4 0.9 0.4 0.1 0.2 0.6 0.2 0.1 0.1 0.5
Medication: Ibuprofen 2.5 3.0 5.3 -1.5 -2.2 -2.1 -1.0 1.0 -1.2 -1.5 -0.2 -2.0 -1.8 -1.4 -0.5 -2.1 -2.2 2.3 -2.1 -1.3 -2.0 -1.9 -1.3 -2.1 -1.5 -1.3 -1.6 -2.2 -1.6 -1.0 -2.1 -2.1 -1.9
Medication: Allopurinol 0.5 0.7 3.2 1.0 0.7 0.6 0.5 -0.5 1.6 0.5 -1.7 1.8 1.2 -0.1 0.4 1.1 0.8 -1.5 0.3 -0.5 0.2 -0.4 1.0 0.3 -0.1 0.1 0.1 0.7 -0.4 0.1 0.4 0.4 0.8
Medication: Omeprazole 1.0 1.2 6.5 -1.4 -0.4 -0.6 -1.4 -2.5 -1.6 -2.1 -1.9 -0.8 -1.1 -1.4 -1.7 -0.6 -0.5 0.3 -0.4 0.8 -0.6 -0.5 -0.3 -0.1 -0.5 -0.5 0.1 -0.5 -1.5 0.7 -0.5 0.4 -1.0
Medication: Seretide 50 evohaler 0.6 0.7 2.4 -0.7 -0.3 -0.6 -1.2 -1.1 -1.1 -1.1 -1.4 -0.2 -0.6 -1.1 -1.2 -0.5 -0.6 0.5 -1.5 -0.6 -0.4 -0.4 -0.4 -0.6 -0.8 -0.7 -0.7 -0.8 -0.6 0.7 -0.5 -0.4 -0.8
Mean time to correctly identify matches 0.4 0.7 2.0 -0.3 -0.1 -1.2 -1.3 -1.3 -1.1 -1.3 -0.9 -0.6 -1.0 -1.0 -1.4 -0.8 -0.3 0.4 -0.2 1.1 -0.3 -0.0 -0.7 -0.4 -0.8 -0.4 0.2 -0.7 -1.2 1.2 -0.4 0.1 -0.8
Heart disease (mother) 2.2 2.7 5.7 1.9 1.2 0.9 0.5 0.1 0.8 1.0 1.5 0.9 0.8 1.3 0.9 1.2 1.9 -1.4 1.9 2.1 2.1 2.1 2.2 2.2 2.3 2.0 1.9 2.0 1.4 1.4 1.9 2.4 1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 1.2 -1.1 -0.7 -0.7 -0.5 -0.7 -0.3 -0.7 0.0 -0.3 -0.7 -0.7 -0.4 -0.5 -0.7 0.5 -0.6 0.2 -0.9 -0.0 -0.4 -0.7 -0.3 -0.2 -0.2 -0.8 -0.9 0.6 -0.5 -0.7 -0.5
Whole body fat mass 0.7 2.7 6.4 1.1 2.4 1.2 0.5 0.2 1.8 1.1 -0.1 2.4 1.5 1.1 1.4 2.1 1.1 -2.1 2.1 2.2 1.9 0.8 2.2 1.5 1.6 2.5 2.2 1.8 1.4 0.5 1.6 1.4 1.8
Leg fat mass (right) 0.4 1.5 3.8 0.6 1.9 0.7 0.1 -0.0 1.3 0.6 -0.4 1.8 1.0 0.7 0.9 1.6 0.8 -1.7 1.7 1.8 1.3 0.4 1.7 1.1 1.1 2.0 1.8 1.4 0.9 0.3 1.2 1.1 1.3
Arm predicted mass (right) 0.1 0.5 2.2 0.2 0.9 -0.4 0.7 -0.4 0.1 1.0 1.4 0.5 0.7 0.8 1.4 0.2 -0.5 -0.0 -0.1 -0.5 0.6 -0.9 0.8 0.3 0.7 1.1 0.4 0.8 1.5 -0.4 0.4 -0.1 0.8
Pulse rate, automated reading 0.5 1.7 7.0 -1.6 -1.4 -0.9 -1.1 0.4 0.2 -0.5 -0.8 -0.2 -0.9 -1.1 -0.1 -1.2 -1.5 1.2 -2.6 -2.0 -1.1 -2.5 -1.2 -1.6 -1.1 -1.1 -1.8 -1.5 0.1 -0.3 -1.0 -2.0 -0.7
Alcohol intake frequency. 0.5 1.3 9.3 -0.6 -0.2 -1.0 -2.7 -1.3 -1.3 -1.3 -1.2 0.1 -1.5 -1.2 -1.6 -0.6 -0.5 -0.1 -0.9 0.6 -0.6 -0.9 -0.4 -0.3 -1.1 -0.7 -0.4 -0.7 -1.2 3.0 0.2 0.4 -0.8
Comparative height size at age 10 0.2 1.3 6.9 1.2 1.2 0.4 -0.3 -2.6 -0.1 0.8 0.0 2.0 1.1 0.3 1.4 0.7 -0.7 -0.8 1.4 0.2 1.6 0.3 1.0 0.9 1.1 0.8 -0.0 1.5 1.9 1.7 1.1 0.5 1.5
Number of full sisters 0.7 0.9 2.7 0.9 1.1 0.5 1.5 -0.0 0.5 1.5 0.6 0.3 1.1 1.6 1.2 0.7 0.9 -0.3 0.6 0.6 1.3 0.6 1.0 1.0 1.3 0.9 1.3 0.7 1.2 -0.1 0.8 0.7 1.1
Suffer from ‘nerves’ 0.6 1.0 8.8 -0.4 -1.6 -0.8 -1.7 -3.0 -0.4 -1.5 -1.2 -0.7 -1.0 -1.1 -0.4 -1.0 -1.4 0.9 -1.0 0.6 -0.4 0.2 0.4 0.0 0.0 0.4 -0.3 -0.4 0.1 1.5 -0.1 0.4 -0.7
Overall health rating 0.8 1.7 7.4 -0.9 -0.3 -1.7 -2.7 -2.0 -0.7 -1.8 -2.4 0.0 -1.7 -1.9 -1.4 -1.1 -1.4 0.7 -0.8 0.1 -0.4 -1.4 -0.6 -0.6 -1.1 -0.7 -0.5 -0.9 -1.0 2.3 -0.2 0.0 -0.9
Chest pain or discomfort 0.7 1.0 7.3 -0.4 -0.8 -1.6 -2.0 -0.4 -0.0 -1.5 -1.6 0.0 -1.4 -1.6 -0.6 -0.8 -1.4 0.9 -0.6 0.3 0.1 -0.4 0.5 -0.2 0.0 0.2 0.5 -0.6 -0.4 2.7 -0.3 0.4 -0.4
Had major operations 1.3 1.6 4.9 -1.4 -2.2 -1.6 -2.0 -1.6 -1.1 -1.5 -1.8 -0.8 -1.9 -1.6 -1.2 -1.5 -1.2 1.2 -0.6 -0.2 -1.1 -0.8 -1.0 -0.8 -0.8 -0.6 -0.3 -0.7 -1.2 1.3 -0.5 -0.2 -1.3
Age at last live birth 1.5 2.2 6.5 -1.0 -1.1 -1.0 -1.0 -1.1 -0.8 -1.2 -1.8 -0.3 -0.6 -1.3 -0.3 -1.0 -1.6 0.7 -1.1 -1.2 -2.1 -1.6 -1.6 -2.4 -2.2 -1.4 -2.3 -2.1 -1.3 -1.4 -1.9 -2.5 -1.5
Family relationship satisfaction 1.0 1.3 4.7 -1.3 -1.1 -0.6 -1.9 -2.2 -1.5 -1.5 -1.3 -0.6 -1.5 -1.3 -1.8 -1.0 -0.7 0.6 -0.2 -0.1 -1.2 -0.3 -1.0 -0.6 -1.1 -0.8 -0.9 -0.9 -0.7 1.6 -0.2 -0.1 -1.2
Leg pain on walking 0.2 0.2 1.2 0.0 0.0 -0.7 -0.6 0.4 0.0 -0.5 -1.1 0.4 -0.4 -0.9 0.1 -0.3 -0.4 0.1 -0.3 -0.0 -0.3 -0.5 -0.4 -0.5 -0.5 -0.1 -0.3 -0.3 -0.1 0.8 -0.2 -0.5 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 2.1 0.6 1.5 0.6 0.8 0.7 -0.7 -0.0 0.8 0.2 0.4 0.2 -0.3 0.6 0.5 -0.6 -0.4 1.0 0.1 -0.2 0.3 0.3 -0.0 0.2 1.0 -0.1 -0.6 -0.3 -0.1 0.4 0.2
Commuting to job workplace: Car/motor vehicle 0.2 0.3 1.6 0.4 0.5 -0.2 -1.3 0.0 0.2 -0.2 0.1 0.9 -0.1 -0.5 -0.2 0.5 0.9 -0.7 0.6 1.0 -0.2 -0.2 0.2 0.1 -0.4 -0.0 -0.4 0.2 -0.8 0.7 0.7 0.3 0.0
Illness, injury, bereavement, stress in last 2 years 1.5 1.9 4.9 1.1 1.3 1.1 0.1 -0.5 1.8 0.2 -0.0 2.2 1.4 0.6 0.1 2.0 1.5 -2.2 0.7 2.1 1.1 1.6 2.1 1.2 1.2 1.7 2.1 1.5 -0.2 1.1 0.7 1.4 1.3
Medication: Aspirin 0.3 0.4 1.8 -1.4 0.2 -0.4 0.1 -0.1 -0.4 -0.6 -1.2 -0.4 -0.2 -0.3 -1.2 -0.2 -0.2 0.0 -0.3 -0.5 -0.4 -0.9 -0.1 -0.5 -0.4 -0.4 0.1 -0.7 -0.7 -0.7 -0.9 -0.4 -0.5
Supplements: Vitamin C 0.3 0.4 2.8 0.9 0.2 0.7 0.2 1.1 1.7 0.6 0.9 0.5 0.5 0.2 0.4 0.2 0.9 -0.8 1.3 -0.1 0.1 -0.1 -0.2 0.2 -0.1 -0.3 -0.1 0.1 0.5 -0.4 0.7 0.0 0.3
Knee pain experienced in last month 0.4 0.5 1.5 0.6 1.0 0.6 -0.3 -0.0 1.2 0.5 0.1 0.7 0.5 0.5 0.4 0.7 0.8 -0.8 1.1 0.9 0.8 0.5 0.7 0.9 0.6 0.6 0.5 1.0 1.0 0.9 0.9 0.8 0.7
Hypertension (Self-reported) 0.3 0.8 3.4 0.8 1.8 0.0 -0.1 -1.4 0.7 -0.3 -0.8 1.0 0.7 -0.0 -0.3 0.8 0.9 -1.3 0.9 1.7 0.7 0.4 1.2 1.0 0.6 1.0 1.1 0.8 0.1 0.9 0.5 1.2 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.8 5.6 1.2 0.9 1.1 -0.7 0.2 0.6 -0.1 0.6 1.8 0.5 -0.3 0.6 1.2 0.7 -1.2 1.3 2.4 1.5 1.4 2.0 1.4 1.5 2.2 1.9 1.5 1.0 2.1 1.4 1.7 1.3
Illnesses of father: Heart disease 0.4 0.6 2.6 -0.8 -1.2 -0.8 -0.9 -0.0 0.6 -1.2 -1.6 -0.4 -1.0 -1.0 -0.8 -1.0 -0.5 0.5 -0.8 0.0 -0.6 -0.9 -0.4 -0.6 -0.4 -0.2 0.1 -0.7 -0.9 0.4 -0.4 -0.4 -0.9
Illnesses of siblings: Diabetes 0.3 0.3 1.4 -0.0 0.4 -0.2 -0.5 0.1 0.7 0.0 -0.6 -0.1 -0.1 0.2 -0.5 0.2 1.2 -0.3 -0.1 0.7 0.4 0.9 0.3 0.7 0.5 0.1 0.9 0.6 -0.5 1.1 0.5 1.1 0.1
Smoking status: Previous 1.2 1.7 4.5 1.3 1.3 1.0 1.6 1.3 -0.3 1.3 1.1 0.4 0.9 1.3 1.3 0.8 1.2 -0.5 2.1 0.2 1.9 1.4 1.9 1.7 1.9 0.7 1.5 0.9 1.1 1.1 1.4 1.8 1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 2.5 -0.2 -0.2 0.2 -0.0 -0.3 -1.2 0.9 -0.3 0.0 -0.2 0.2 0.7 -0.7 -0.8 0.8 0.0 -1.5 0.1 0.1 -0.5 -0.3 -0.2 -0.3 -1.3 -0.2 1.6 0.8 0.1 -0.6 0.1
Whole body fat-free mass 0.1 0.5 2.2 0.1 0.9 -0.3 0.4 -0.4 0.3 1.1 1.0 0.6 0.6 0.9 1.2 0.3 -0.4 -0.2 -0.1 -0.5 0.5 -0.8 0.6 0.3 0.6 1.0 0.3 0.7 1.5 -0.4 0.5 -0.1 0.7
Leg fat-free mass (right) 0.1 0.5 2.2 0.3 1.1 0.0 0.7 0.2 0.5 1.2 1.2 0.8 0.8 0.8 1.5 0.6 -0.2 -0.5 0.2 0.0 0.5 -0.7 0.7 0.3 0.5 1.0 0.5 0.7 1.2 -0.7 0.6 -0.1 0.8
Arm fat percentage (left) 1.0 3.9 9.7 1.3 2.6 1.6 0.5 1.0 2.7 1.0 -0.6 2.7 1.5 1.1 1.4 2.6 1.7 -2.6 2.5 3.1 2.1 1.6 2.5 1.8 1.9 2.9 2.7 2.0 1.1 0.7 1.9 1.9 2.0
Average weekly red wine intake 1.1 1.7 4.5 -1.4 -2.1 -1.7 -1.3 -1.9 -1.1 -1.6 -1.0 -1.2 -1.5 -1.5 -2.1 -1.4 -1.1 0.9 -0.4 -0.2 -1.7 -1.4 -1.5 -0.9 -1.3 -1.1 -0.8 -0.7 -1.3 -0.1 -1.0 -0.4 -1.4
Handedness (chirality/laterality): Left-handed 0.6 0.7 2.5 -1.2 -0.0 -0.6 0.2 -0.2 0.2 -0.7 -1.4 -0.9 -0.3 -0.6 -0.1 -0.8 -0.8 0.9 -1.2 -1.0 -0.7 -1.6 -0.6 -1.1 -0.7 -0.5 -0.7 -0.9 -0.4 -0.9 -1.2 -1.3 -0.8
Mood swings 1.0 1.8 6.4 -1.1 -1.4 -1.1 -2.0 -2.5 -1.2 -1.7 -1.5 -1.7 -1.9 -1.2 -1.2 -1.9 -1.7 1.6 -1.1 -0.1 -0.9 -0.9 -0.9 -0.7 -1.0 -0.7 -1.1 -1.2 -0.7 1.0 -0.6 -0.2 -1.6
Loneliness, isolation 0.4 0.5 2.5 0.5 -0.8 -0.1 -1.3 -1.6 0.7 -0.7 -0.4 0.4 -0.5 -0.6 0.1 0.0 -0.3 -0.3 0.8 1.6 -0.1 1.0 -0.1 0.4 0.2 0.4 0.3 0.1 -0.0 1.5 0.8 0.7 -0.0
Long-standing illness, disability or infirmity 0.6 0.9 3.5 -0.6 -0.8 -1.7 -1.7 -1.2 0.1 -1.4 -1.9 -0.3 -1.4 -1.2 -0.9 -1.1 -1.2 0.7 -1.1 0.6 -0.4 -0.8 -0.1 -0.5 -0.6 0.3 -0.1 -0.6 -0.4 1.3 -0.2 -0.0 -0.8
Ever had bowel cancer screening 1.3 1.6 3.9 -1.3 -1.0 -1.1 -1.7 -2.0 -1.0 -1.5 -0.7 -0.9 -1.2 -1.3 -1.5 -1.2 -1.3 0.7 -1.2 -1.0 -1.4 -1.6 -1.0 -1.0 -1.4 -1.6 -1.5 -1.2 -1.4 0.3 -0.9 -0.7 -1.3
Diabetes diagnosed by doctor 0.2 0.4 1.6 -0.2 0.2 -1.3 -1.1 0.2 -0.2 -0.8 0.0 -0.3 -0.8 -0.8 -1.0 -0.5 -0.4 -0.0 -0.6 0.4 -0.7 -1.1 -0.8 -0.2 -0.6 -1.0 -0.5 -0.4 -0.5 0.4 -0.2 0.1 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 1.2 -0.7 0.4 0.4 0.5 -0.7 -0.1 -0.4 1.1 -0.3 0.0 0.1 0.0 -0.1 -0.2 0.1 -0.4 0.9 -0.4 0.1 -0.2 -0.4 -0.1 0.4 0.0 -0.4 -0.1 -1.0 -0.3 -0.6 -0.4
Friendships satisfaction 0.2 0.3 2.4 -0.3 -0.4 -0.3 -0.4 -0.4 -0.5 -0.3 -1.6 -0.3 -0.1 -0.1 -1.1 -0.1 0.4 -0.1 -0.4 -0.0 0.2 0.0 0.7 0.4 0.1 0.5 0.6 0.4 -0.2 0.5 0.1 0.8 -0.0
Qualifications: nursing, teaching 0.4 0.7 5.3 -0.4 -1.1 -0.2 0.7 0.8 0.9 0.2 -0.2 -0.1 0.3 -0.0 0.8 -0.2 -0.4 0.4 -0.5 -1.5 -1.0 -0.1 -0.9 -1.2 -0.7 -0.3 -0.8 -0.6 -0.0 -2.3 -0.9 -1.6 -0.5
Commuting to job workplace: Walk 0.2 0.2 2.1 0.0 0.1 0.1 0.7 -1.0 -0.6 0.3 1.4 -0.4 0.2 0.4 0.2 -0.3 -0.5 0.5 0.0 -0.4 0.1 0.5 -0.2 0.0 0.2 0.5 0.3 0.3 0.6 -0.5 -0.2 -0.1 0.1
Eye problems/disorders: Cataract 2.0 2.3 4.6 -2.1 -1.3 -1.9 -1.3 -1.0 -1.1 -1.4 -0.9 -1.6 -1.4 -1.1 -1.5 -1.5 -1.4 1.6 -1.9 -1.0 -1.6 -2.0 -1.9 -1.6 -1.4 -1.7 -1.7 -1.8 -0.9 -0.4 -1.6 -1.7 -1.6
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 7.8 -1.2 -1.5 -0.8 -1.4 0.1 -0.2 -2.0 -2.8 -0.5 -1.4 -2.0 -1.2 -0.9 -0.8 0.7 -0.4 0.3 -1.0 -1.0 -0.7 -0.8 -1.0 -0.7 0.2 -0.9 -1.7 1.2 -0.8 -0.2 -1.1
Medication for cholesterol 0.2 0.3 1.4 -0.5 -1.2 -0.7 -0.3 0.6 -0.9 -0.0 -0.1 -0.5 -0.5 -0.5 -0.4 -0.7 -0.5 0.8 -0.2 -0.5 -0.5 0.1 -0.6 -0.4 -0.5 -0.5 -0.8 -0.3 -0.4 0.2 -0.3 -0.4 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 6.8 -0.3 -0.8 -1.2 -2.1 -1.5 -0.3 -1.3 -1.2 0.1 -1.4 -1.6 -1.4 -0.8 -0.7 0.4 0.6 0.7 0.4 -0.0 0.1 0.3 -0.1 0.4 1.1 0.3 -0.8 2.6 0.5 1.2 -0.3
Back pain experienced in last month 1.2 1.7 4.8 -1.2 -0.5 -1.4 -1.7 -2.1 0.0 -1.4 -1.6 -0.6 -1.4 -1.5 -1.4 -1.2 -1.3 0.8 -0.4 -1.2 -1.0 -2.2 -1.3 -1.2 -1.7 -1.8 -1.2 -1.3 -1.4 0.7 -0.9 -0.9 -1.3
Mineral and other dietary supplements 1.5 2.0 6.0 -1.7 -1.6 -1.7 -0.5 0.2 -1.4 -1.0 -1.3 -1.8 -1.7 -0.7 -0.6 -1.9 -1.8 2.0 -2.5 -0.9 -1.2 -0.9 -1.5 -1.7 -1.1 -0.6 -0.9 -1.8 -1.1 -0.6 -1.4 -1.6 -1.7
Breast cancer (self-reported) 0.8 0.9 2.6 -1.6 -1.6 -0.5 -0.4 0.4 -1.6 -0.7 -1.4 -1.1 -0.7 -0.7 -0.4 -1.1 -1.2 1.2 -1.5 -1.1 -0.8 -0.7 -0.4 -0.8 -0.5 -0.6 -0.8 -1.3 0.0 -0.1 -1.0 -0.9 -0.8
Asthma (self-reported) 0.2 0.4 1.5 0.1 -0.3 -0.4 -0.4 0.8 1.0 -0.7 -1.2 -0.1 -0.4 -0.6 -0.4 0.0 0.3 0.1 -1.2 0.7 0.6 0.0 0.6 0.6 0.4 0.4 1.2 0.2 -0.2 1.1 0.1 1.0 0.1
Osteoporosis (self-reported) 0.6 0.8 5.2 -0.8 -0.6 -1.0 -0.4 -0.9 -1.6 -1.0 -0.5 -1.6 -0.9 -0.4 -2.3 -0.7 0.2 0.8 -0.4 0.6 -0.4 -0.2 -0.8 0.1 -0.5 -1.3 -0.1 -0.4 -1.5 -0.1 -0.7 0.5 -0.9
Osteoarthritis (self-reported) 1.2 1.6 3.6 0.9 1.9 1.4 -0.3 1.1 1.4 0.0 -1.1 1.5 0.5 0.2 -0.1 1.3 1.0 -1.3 1.6 1.3 1.6 0.7 1.8 1.4 1.0 1.6 1.6 1.4 0.8 1.8 1.3 1.8 1.0
Medication: Aspirin 0.2 0.3 1.9 -1.2 0.4 -0.2 -0.1 -0.2 -0.2 -0.8 -1.4 -0.1 -0.2 -0.5 -1.2 -0.0 -0.1 -0.1 -0.3 -0.2 -0.2 -0.6 -0.1 -0.3 -0.3 -0.2 0.3 -0.3 -0.5 -0.4 -0.7 -0.1 -0.4
Medication: Gliclazide 0.2 0.3 1.4 -0.2 -0.7 -0.4 0.1 0.4 0.7 0.4 0.0 -0.4 -0.4 0.1 -0.5 -0.4 0.1 0.2 -0.4 -1.0 -0.1 -1.0 -0.4 0.1 -0.2 -1.2 -1.0 -0.1 0.2 0.5 0.2 0.1 -0.1
Illnesses of father: None of the above (group 1) 1.5 1.8 4.3 1.5 2.0 1.2 1.0 -0.1 -0.2 1.5 1.6 1.6 1.4 1.4 1.5 1.7 1.4 -1.3 2.1 1.1 1.5 1.6 0.9 1.2 1.3 0.9 0.8 1.3 1.6 0.4 1.5 0.9 1.6
Smoking status: Current 0.1 0.2 1.1 -0.4 -0.7 -0.4 -0.8 0.3 0.1 -0.2 -0.7 -0.7 -0.8 -0.2 0.1 -0.9 -0.6 1.1 -0.5 -0.2 -0.2 -0.4 -0.5 -0.3 0.0 0.2 0.4 -0.3 -0.4 0.3 -0.0 -0.2 -0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.4 7.3 -1.5 -1.4 -0.8 -0.1 -1.0 -1.2 -0.1 -0.1 -2.0 -1.1 -0.1 -0.1 -2.0 -1.7 2.1 -1.1 -2.7 -1.4 -2.1 -1.6 -1.9 -1.7 -1.3 -2.4 -1.9 -0.3 -1.7 -1.4 -2.1 -1.7
Whole body water mass 0.1 0.4 2.1 0.1 0.8 -0.4 0.5 -0.3 0.2 1.1 1.1 0.5 0.5 0.9 1.2 0.2 -0.4 -0.1 -0.2 -0.5 0.4 -0.9 0.6 0.2 0.5 1.0 0.3 0.7 1.5 -0.4 0.4 -0.2 0.6
Leg predicted mass (right) 0.1 0.5 2.0 0.2 1.1 -0.0 0.7 0.2 0.5 1.2 1.2 0.8 0.7 0.8 1.4 0.6 -0.2 -0.4 0.1 -0.0 0.5 -0.7 0.7 0.2 0.5 1.0 0.5 0.6 1.2 -0.7 0.5 -0.1 0.8
Arm fat mass (left) 0.6 2.6 6.4 1.0 2.3 1.0 0.3 0.3 2.1 1.1 -0.3 2.3 1.3 1.1 1.4 2.0 1.2 -2.0 1.9 2.2 1.8 0.8 2.1 1.5 1.6 2.5 2.1 1.8 1.3 0.6 1.7 1.4 1.7
Number of self-reported non-cancer illnesses 0.3 0.5 4.5 0.8 0.7 0.1 -0.3 0.6 0.7 -0.6 0.1 0.2 -0.0 -0.1 0.0 0.4 0.6 -0.5 0.3 2.1 0.5 0.0 1.1 0.7 0.6 1.1 1.4 0.4 -0.2 0.6 0.4 1.0 0.2
Average weekly champagne plus white wine intake 1.1 1.6 5.2 -1.4 -1.2 -0.5 -1.6 -1.1 -1.7 -1.9 -1.5 -0.7 -1.0 -1.7 -2.3 -0.8 -0.6 0.4 -0.2 -0.1 -2.0 -0.8 -1.1 -1.1 -1.7 -1.0 -0.9 -1.1 -1.6 -0.2 -1.4 -0.8 -1.5
Miserableness 0.3 0.5 4.1 0.3 0.5 0.2 -1.4 -2.0 0.1 -1.0 -0.7 0.6 -0.6 -0.8 -0.3 -0.2 -0.7 0.1 -0.4 1.2 0.4 0.7 0.6 0.1 0.1 0.8 -0.2 0.1 -0.0 1.6 0.3 0.6 -0.0
Guilty feelings 0.6 1.0 6.4 -0.5 -1.0 -0.7 -1.3 -1.3 -0.0 -2.2 -2.5 -0.1 -1.0 -1.9 -1.3 -0.5 -0.8 0.3 -0.2 0.8 -0.5 0.3 0.2 -0.4 -0.4 0.4 0.1 -0.2 -1.0 0.8 -0.7 0.2 -0.8
Wears glasses or contact lenses 0.5 0.6 2.5 0.3 0.7 0.7 0.1 -0.1 1.6 0.3 -0.3 0.6 0.7 0.7 0.5 1.0 1.1 -1.1 0.6 1.4 0.5 0.7 1.0 0.7 1.1 0.8 0.9 0.5 0.0 -0.1 0.6 0.6 0.6
Ever taken oral contraceptive pill 0.5 0.5 2.9 -0.8 -1.3 -0.0 0.6 -1.2 0.5 0.2 0.1 -0.8 -0.4 0.1 0.5 -1.0 -1.3 0.9 -0.1 -1.7 -0.8 -0.7 -0.5 -0.6 -0.3 -0.3 -0.5 -0.6 -0.1 -1.0 -0.3 -0.7 -0.5
Hearing aid user 0.2 0.2 1.0 -0.3 0.6 0.6 -0.0 -0.3 0.3 0.6 1.0 0.6 0.7 0.7 0.7 0.6 -0.1 -0.4 0.0 0.3 0.1 0.4 0.2 0.0 0.4 -0.1 -0.7 -0.1 0.7 -0.1 0.3 -0.4 0.5
Mother’s age at death 0.3 0.4 2.0 -0.4 0.3 -0.3 1.0 1.4 -0.7 -0.2 -0.6 -0.9 -0.1 -0.2 -0.2 -0.2 0.2 0.8 -0.7 -0.6 -0.2 -0.3 -0.4 -0.3 -0.3 -0.8 -0.3 -0.2 -0.7 -1.4 -0.8 -0.3 -0.4
Financial situation satisfaction 0.2 0.3 1.9 0.4 0.5 -0.0 -0.6 -0.5 -0.8 0.1 -0.6 1.1 0.1 -0.2 0.4 0.5 -0.1 -0.5 0.4 0.3 0.4 -0.1 0.5 0.2 0.3 0.4 0.6 0.1 -0.1 1.4 0.6 0.4 0.5
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.9 -0.5 -0.2 -0.6 -0.7 -0.6 0.1 -0.5 -0.1 0.5 -0.2 -0.9 -0.2 -0.1 0.0 -0.0 -0.2 -0.4 -0.2 -0.3 0.1 -0.2 -0.2 -0.0 -0.3 -0.1 -0.0 0.8 0.0 -0.1 0.0
Commuting to job workplace: Public transport 0.2 0.2 1.3 -0.2 -0.4 -0.0 -0.2 -0.6 0.9 -0.4 -0.8 0.3 -0.1 -0.3 -0.3 0.0 -0.8 -0.1 -1.2 0.1 -0.2 0.6 0.2 -0.0 0.0 0.6 0.2 0.1 0.5 0.3 -0.1 0.1 -0.0
Eye problems/disorders: Glaucoma 1.1 1.3 5.7 -0.4 -0.7 -0.7 0.8 0.4 -0.6 0.1 -0.9 -0.9 0.1 0.2 0.3 -0.8 -0.3 0.7 -1.3 -1.5 -1.3 -2.0 -1.0 -1.6 -1.2 -0.8 -0.8 -1.6 -1.2 -2.4 -1.4 -2.0 -1.0
Medication: Blood pressure 0.3 0.5 2.7 -0.3 0.7 -0.9 -0.6 0.0 -1.0 -1.3 -1.7 -0.4 -0.5 -1.0 -1.2 -0.2 -0.2 -0.1 0.0 -0.0 -0.4 -1.2 -0.2 -0.2 -0.7 -0.7 0.1 -0.5 -0.7 0.1 -0.9 0.1 -0.7
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.9 0.5 0.8 0.5 -0.7 -0.1 -0.0 0.2 -0.0 0.9 0.0 -0.2 0.2 0.3 0.4 -0.4 1.7 -0.2 0.8 0.2 0.9 0.8 0.5 0.1 0.1 1.0 0.8 1.3 1.0 1.0 0.6
Supplements: Fish oil (including cod liver oil) 0.8 1.0 3.2 0.7 0.9 1.5 -0.7 -1.1 0.7 -0.1 1.0 1.7 0.9 -0.1 -0.4 1.4 1.2 -1.8 1.6 0.8 0.4 0.8 1.1 1.0 0.4 0.3 0.6 1.1 0.1 1.3 0.9 1.3 0.9
High cholesterol (Self-reported) 2.4 4.2 10.9 2.1 2.1 1.6 0.5 0.8 1.1 1.5 0.6 1.6 1.1 1.5 0.7 1.7 2.5 -2.2 2.4 2.2 2.7 1.2 2.8 2.9 2.3 2.1 3.0 2.3 1.8 2.2 2.5 3.3 2.1
Medication: Bendroflumethiazide 1.0 1.5 4.6 0.8 1.8 0.7 0.4 -2.0 0.4 -0.2 -0.5 0.5 1.2 0.6 -1.3 1.4 1.8 -2.0 0.9 2.0 1.0 0.9 1.5 1.6 0.7 0.6 1.8 1.1 -0.4 0.3 0.6 2.1 0.6
Medication: Paracetamol 0.2 0.3 2.0 0.5 0.5 0.1 -0.9 -0.8 0.2 -0.9 -0.7 0.8 0.2 -0.7 -0.1 0.4 0.0 -0.6 0.0 1.4 -0.0 -0.2 0.4 -0.1 -0.2 0.2 -0.3 0.0 -0.5 0.3 -0.2 -0.1 0.1
Medication: Lisinopril 0.5 0.7 3.0 1.3 0.9 0.8 1.0 0.5 0.5 1.3 0.2 -0.0 0.9 1.1 0.8 0.1 0.9 -0.4 0.7 -1.0 1.1 0.4 0.3 1.0 0.7 0.0 0.0 0.7 1.7 -0.5 0.8 0.7 0.7
Medication: Atorvastatin 0.9 1.1 6.1 -0.8 -0.7 -0.9 -1.9 -2.1 -0.9 -1.3 -0.3 -0.6 -1.2 -0.7 -1.5 -0.6 0.0 0.3 -0.4 1.9 0.1 -0.6 0.2 0.4 0.1 -0.3 0.7 -0.5 -1.2 2.5 0.2 1.1 -0.5
Illnesses of father: High blood pressure 1.1 1.4 11.6 0.8 1.0 0.6 2.4 3.4 0.7 1.6 0.9 0.2 1.2 1.3 1.6 0.6 0.4 -0.2 -0.5 -0.3 0.8 0.2 0.7 0.2 0.8 1.0 0.1 0.6 1.3 -2.4 0.1 -0.5 0.9
Alcohol drinker status: Never 1.4 1.7 8.0 -1.1 -1.4 -0.6 -1.7 -2.8 -1.2 -2.4 -1.3 -1.2 -1.4 -1.9 -1.3 -1.3 -1.2 1.1 -0.1 0.0 -1.2 -0.1 -1.1 -0.8 -0.9 -0.8 -0.5 -0.8 -2.0 0.7 -1.1 -0.2 -1.5
Ever smoked 1.3 2.3 5.6 1.5 0.8 1.6 2.0 1.8 1.4 1.9 1.0 0.7 1.2 1.7 2.1 0.7 1.1 -0.6 1.8 0.0 2.0 1.9 1.5 1.8 2.4 0.9 1.4 1.3 1.8 0.4 1.7 1.4 1.8
Basal metabolic rate 0.1 0.6 2.2 0.2 1.2 -0.1 0.4 -0.3 0.4 1.1 0.8 0.9 0.7 0.9 1.3 0.5 -0.2 -0.5 0.2 -0.1 0.7 -0.7 0.9 0.5 0.7 1.3 0.6 0.9 1.5 -0.2 0.7 0.1 0.9
Leg fat percentage (left) 0.3 1.0 4.6 0.2 1.5 0.3 -0.8 -0.5 0.7 -0.6 -1.2 1.4 0.2 -0.3 -0.2 1.2 0.4 -1.5 1.8 2.1 0.8 0.2 1.2 0.8 0.5 1.2 1.5 0.8 -0.2 1.3 0.8 1.2 0.6
Arm fat-free mass (left) 0.1 0.3 2.0 -0.4 0.5 -1.0 -0.3 -0.8 -0.5 0.3 0.6 0.2 -0.1 0.2 0.6 -0.3 -0.8 0.3 -0.5 -0.8 -0.0 -1.4 0.1 -0.3 -0.1 0.4 -0.3 0.2 0.8 -0.1 -0.1 -0.5 0.1
Number of operations (self-reported) 0.8 1.1 4.9 -1.1 -1.3 -0.9 -2.2 -1.2 -0.3 -1.8 -1.5 -0.3 -1.6 -1.9 -0.9 -0.9 -1.3 0.7 -0.7 0.6 -0.9 -0.2 -0.8 -0.6 -0.6 -0.4 -0.7 -0.4 -1.0 1.4 -0.5 -0.2 -1.0
Average weekly beer plus cider intake 0.7 1.0 4.2 -0.4 -1.0 -0.4 -0.4 -0.6 -2.1 -0.6 -0.7 -1.2 -0.6 -0.5 -0.5 -0.8 -0.8 1.3 -0.8 -1.5 -1.2 -0.8 -1.6 -1.0 -1.0 -1.4 -1.1 -0.9 -0.7 -0.5 -1.1 -1.1 -1.0
Irritability 0.3 0.5 2.1 -0.0 -0.4 0.4 -0.9 -1.2 -0.3 -0.9 -1.2 -0.2 -0.5 -0.6 -0.7 -0.2 0.1 -0.1 0.4 1.0 0.5 1.0 0.5 0.9 0.6 0.5 0.5 0.7 0.2 1.4 0.5 1.5 -0.0
Risk taking 0.9 1.3 4.9 -1.3 -1.5 -0.9 -1.6 0.4 -0.3 -1.4 -2.2 -0.6 -1.7 -1.5 -1.0 -1.1 -1.7 1.2 -0.3 -0.3 -1.2 -0.9 -0.8 -1.1 -1.0 -0.4 -0.2 -0.8 -1.6 0.7 -1.0 -0.6 -1.2
Ever had prostate specific antigen (PSA) test 0.9 1.1 5.1 1.1 0.7 0.6 0.1 -2.3 0.5 0.2 0.7 1.2 0.5 0.4 0.5 0.9 0.6 -0.9 1.2 1.5 0.8 1.7 0.9 1.0 0.8 1.5 1.3 1.3 1.0 0.5 1.2 1.3 0.9
Fractured/broken bones in last 5 years 3.3 4.2 8.6 -2.3 -2.2 -1.5 -2.4 -2.6 -2.9 -2.6 -1.5 -2.5 -2.7 -2.3 -2.9 -2.3 -2.2 2.2 -1.1 -1.5 -1.7 -1.1 -2.1 -1.4 -2.0 -2.1 -2.0 -1.7 -1.5 0.9 -1.8 -0.6 -2.4
Age started oral contraceptive pill 1.2 1.5 3.6 -1.1 -1.1 -1.1 -1.4 -0.9 0.1 -1.5 -1.0 -0.4 -1.1 -1.7 -1.0 -1.0 -1.5 0.6 -0.7 -1.5 -1.4 -1.1 -1.3 -1.6 -1.5 -1.4 -1.9 -1.2 -1.0 -0.2 -1.5 -1.5 -1.2
Diastolic blood pressure, automated reading 0.2 0.7 2.4 -1.0 -0.2 -1.0 -0.2 -0.5 -1.1 -0.8 -0.1 -1.0 -0.3 -0.2 -0.8 -0.4 -0.1 0.6 -1.1 -0.5 -0.9 0.1 -1.3 -0.9 -0.7 -1.1 -1.6 -0.9 -0.6 -1.4 -1.2 -1.2 -0.8
Ever depressed for a whole week 2.2 2.7 12.2 2.1 1.3 1.5 1.9 1.9 2.5 2.7 1.2 1.7 2.0 2.0 3.5 1.4 0.8 -1.2 0.9 -0.3 1.2 1.8 0.7 0.7 1.3 1.5 0.3 1.0 2.3 -0.9 1.6 -0.1 1.7
Unable to work because of sickness or disability 0.9 1.2 2.9 -1.0 -0.8 -1.6 -1.5 -0.8 -1.4 -1.4 -0.7 -0.4 -1.3 -1.7 -1.0 -1.2 -1.2 1.0 -0.7 -0.8 -0.4 -1.5 -0.8 -0.8 -0.9 -1.1 -1.1 -1.0 -0.5 1.7 -0.7 -0.6 -0.8
Commuting to job workplace: Cycle 0.3 0.3 3.1 0.0 -0.4 0.2 1.1 0.8 0.8 0.2 0.2 -0.8 0.2 0.9 -0.1 -0.0 0.3 0.0 -0.0 0.4 -0.5 0.3 -0.1 -0.2 0.0 0.7 1.8 -0.2 -1.0 -0.7 -0.5 -0.2 -0.4
Myopia 1.0 1.5 5.7 1.6 0.1 1.1 1.9 0.7 1.4 1.9 1.9 0.8 1.3 1.6 2.4 0.9 0.8 -0.7 1.1 0.2 0.8 1.2 0.4 0.6 0.9 1.2 0.5 1.0 1.7 -1.5 1.1 0.1 1.2
Vascular/heart problems diagnosed by doctor 0.4 1.2 3.8 -0.7 -1.7 0.1 0.4 1.4 -0.3 0.5 1.4 -1.3 -0.6 0.3 0.6 -0.9 -1.0 1.5 -0.8 -2.0 -0.7 -0.1 -1.5 -1.1 -0.7 -1.1 -1.8 -0.9 0.3 -1.5 -0.8 -1.6 -0.8
Cholesterol lowering medication 0.2 0.4 1.4 0.3 0.8 0.3 -0.3 -0.9 1.0 -0.1 0.6 0.0 0.2 0.4 -0.4 0.4 0.9 -0.8 0.2 0.8 0.6 -0.6 0.8 0.8 0.3 0.3 0.8 0.4 0.0 0.6 0.5 1.2 0.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 6.1 -1.1 -0.2 -0.0 -0.4 -2.5 -0.9 -1.5 -0.6 -0.6 -0.4 -0.7 -0.7 -0.2 -0.5 0.3 0.1 0.7 -0.4 -0.1 -0.1 -0.1 0.0 0.1 0.4 -0.2 -0.8 -0.0 -0.5 0.1 -0.6
Pain experienced in last month 0.7 1.2 5.8 -1.3 -1.5 -0.1 1.1 -0.5 -1.8 -0.3 0.6 -2.0 -0.1 0.3 -0.7 -0.6 -0.2 1.1 -1.3 -0.7 -1.4 -0.3 -1.1 -0.9 -0.7 -0.8 -0.7 -1.1 -1.2 -2.4 -1.4 -1.0 -1.1
Supplements: Calcium 0.7 0.8 3.0 0.8 0.5 1.1 0.3 -0.3 1.7 0.7 0.2 0.7 0.6 0.6 1.0 0.6 0.8 -0.6 1.7 0.9 1.0 0.9 0.6 1.0 1.0 0.8 0.7 1.0 0.9 0.6 1.1 0.8 0.8
Basal cell carcinoma (self-reported) 1.8 2.1 4.4 1.6 1.4 1.5 1.5 0.1 0.7 1.9 0.2 1.4 2.1 1.9 1.5 1.7 1.7 -1.4 0.4 1.2 1.8 1.5 1.6 1.4 1.7 1.7 1.2 1.8 1.8 -0.6 1.2 0.8 1.8
Heart attack/myocardial infarction (self-reported) 0.3 0.4 2.5 -0.1 -0.2 -0.6 -0.5 -0.4 -0.7 -0.6 -0.7 0.1 -0.3 -0.4 -0.0 -0.1 -0.3 0.1 -0.4 1.1 0.3 -0.3 0.6 0.4 0.7 0.6 1.6 0.2 -0.8 1.1 0.2 0.8 0.1
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 3.2 -0.5 -0.3 -0.7 0.3 -0.0 -1.8 -0.0 -0.6 -0.5 0.0 0.0 0.2 -0.3 -0.2 0.5 -0.1 -0.2 -0.7 -0.2 -0.7 -0.8 -0.3 -0.1 -0.2 -0.6 -0.3 -1.4 -0.9 -1.0 -0.4
Heart disease (siblings) 1.2 1.5 4.1 1.4 1.5 0.8 -0.7 -1.0 0.9 0.4 2.0 1.6 0.7 0.2 0.4 1.2 1.1 -1.7 1.3 1.5 1.1 0.6 1.4 1.5 0.8 0.7 1.8 1.1 -0.1 1.7 1.6 2.0 1.1
Alcohol drinker status: Previous 0.2 0.2 2.4 -0.4 -0.1 0.3 -0.6 0.7 0.2 -0.1 -1.6 0.6 -0.2 -0.2 -0.4 0.0 -0.2 -0.5 -0.3 0.2 -0.2 0.1 0.0 -0.3 -0.3 0.5 0.0 -0.3 0.5 1.0 0.0 -0.2 -0.1
Pack years of smoking 0.3 0.5 1.9 -0.2 -0.3 -0.3 -1.3 -0.5 0.5 -0.6 0.6 0.4 -0.2 -0.9 -1.4 0.4 1.0 -0.9 -0.1 0.3 -0.7 -1.0 -0.7 0.1 -0.7 -1.4 -0.5 -0.0 -1.3 0.2 0.0 0.2 -0.2
Impedance of whole body 0.1 0.5 2.8 0.6 -0.4 1.1 -0.4 -0.9 -0.5 -0.3 -1.4 0.9 0.3 -0.7 0.3 0.2 -0.2 -0.2 1.3 0.5 0.9 1.7 0.2 0.3 0.3 0.3 -0.1 0.4 0.8 1.1 0.4 0.4 0.5
Leg fat mass (left) 0.3 1.0 2.9 0.4 1.7 0.4 -0.2 -0.3 0.9 0.3 -0.4 1.6 0.7 0.4 0.6 1.3 0.4 -1.4 1.5 1.6 1.0 0.1 1.4 0.9 0.8 1.6 1.4 1.1 0.6 0.5 0.9 0.9 1.0
Arm predicted mass (left) 0.1 0.3 1.5 0.1 0.8 -0.6 -0.0 -0.5 0.1 0.7 0.8 0.5 0.3 0.5 1.0 0.0 -0.4 -0.0 -0.0 -0.5 0.3 -1.1 0.4 0.1 0.3 0.8 0.1 0.5 1.2 0.0 0.3 -0.2 0.5