TWAS hub - RHPN2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1900	0.0370	3.1e-15	0.165	0.149	0.177	0.137	0.173	1.5e-19	1.1e-17	5.6e-21	2.7e-16	1.3e-20
2	GTEx	Artery Aorta	0.1270	0.0440	6.4e-04	0.089	NA	0.052	NA	0.074	1.3e-05	NA	7.7e-04	NA	7.0e-05
3	GTEx	Artery Tibial	0.0887	0.0325	4.4e-04	0.092	NA	0.111	NA	0.095	1.1e-07	NA	5.1e-09	NA	6.8e-08
4	GTEx	Brain Caudate basal ganglia	0.2020	0.0870	3.9e-03	-0.010	NA	0.030	NA	-0.008	9.7e-01	NA	4.8e-02	NA	6.7e-01
5	GTEx	Brain Hippocampus	0.2231	0.0987	6.2e-03	-0.013	NA	0.000	NA	-0.011	9.3e-01	NA	3.3e-01	NA	7.0e-01
6	GTEx	Cells Transformed fibroblasts	0.0800	0.0340	4.0e-03	0.005	NA	0.005	NA	0.002	1.3e-01	NA	1.2e-01	NA	2.2e-01
7	GTEx	Esophagus Muscularis	0.2040	0.0760	2.9e-04	0.075	NA	0.097	NA	0.079	2.6e-05	NA	1.7e-06	NA	1.6e-05
8	GTEx	Muscle Skeletal	0.0555	0.0211	1.6e-03	0.048	NA	0.047	NA	0.048	1.7e-05	NA	2.2e-05	NA	1.6e-05
9	GTEx	Nerve Tibial	0.1661	0.0495	7.2e-06	0.086	NA	0.116	NA	0.098	1.1e-06	NA	1.5e-08	NA	2.0e-07
10	GTEx	Skin Sun Exposed Lower leg	0.1540	0.0480	9.9e-04	0.066	NA	0.046	NA	0.041	3.9e-06	NA	1.0e-04	NA	2.5e-04
11	GTEx	Thyroid	0.1820	0.0610	6.3e-05	0.017	NA	0.049	NA	0.030	1.8e-02	NA	1.2e-04	NA	2.2e-03
12	METSIM	Adipose	0.1122	0.0277	3.6e-12	0.048	0.106	0.082	0.105	0.069	1.1e-07	1.5e-15	2.7e-12	2.1e-15	1.5e-10
13	TCGA	Breast Invasive Carcinoma	0.0213	0.0103	2.3e-04	0.011	0.020	0.018	NA	0.016	2.1e-03	4.2e-05	8.7e-05	NA	2.9e-04
14	TCGA	Colon Adenocarcinoma	0.1160	0.0580	9.1e-04	0.012	0.050	0.033	NA	0.022	6.6e-02	7.5e-04	5.0e-03	NA	1.9e-02
15	TCGA	Glioblastoma Multiforme	0.1120	0.0630	6.7e-03	0.014	0.003	-0.004	NA	-0.009	1.2e-01	2.5e-01	4.6e-01	NA	7.4e-01
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0457	0.0250	4.6e-03	0.006	0.027	0.004	NA	0.002	5.8e-02	4.6e-04	1.1e-01	NA	1.6e-01
17	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2070	0.0880	4.6e-05	0.022	0.078	0.067	NA	0.045	1.9e-02	3.2e-05	1.0e-04	NA	1.3e-03
18	TCGA	Brain Lower Grade Glioma	0.0451	0.0184	1.5e-06	0.029	0.047	0.048	NA	0.042	2.4e-04	4.6e-06	3.5e-06	NA	1.3e-05
19	TCGA	Lung Squamous Cell Carcinoma	0.0409	0.0216	1.3e-03	0.022	0.016	0.011	NA	0.015	1.4e-03	5.1e-03	1.7e-02	NA	7.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Heel T-Score	64.5	512.7	1017.6	-27.2	-24.8	-26.0	-17.5	-22.1	-11.9	-11.9	-25.2	-21.5	5.4	-16.6	-15.1	-28.7	-19.8	-31.9	-26.8	-26.4	-29.5	-22.0
Heel bone mineral density (BMD) T-score, automated (right)	45.5	104.3	207.4	-12.1	-10.8	-11.0	-8.9	-11.3	-6.3	-5.4	-10.8	-7.8	2.4	-7.4	-8.0	-12.9	-8.6	-14.4	-12.6	-12.2	-13.4	-9.2
Heel bone mineral density (BMD) T-score, automated (left)	45.0	102.1	201.6	-12.0	-11.2	-11.0	-8.9	-11.0	-6.2	-4.8	-11.0	-8.1	2.1	-6.8	-7.9	-12.7	-8.6	-14.2	-12.3	-11.8	-13.4	-9.1
Health satisfaction	6.7	8.7	13.7	-2.9	-2.4	-2.7	-1.3	-2.9	-2.5	-3.1	-3.1	-3.0	-1.6	-2.9	-2.9	-3.6	-3.7	-2.9	-3.4	-3.3	-3.6	-3.2
Primary Biliary Cirrhosis	6.4	9.1	15.4	-3.7	-2.7	-2.0	-3.4	-3.9	-1.7	-2.6	-3.4	-2.5	-1.0	-2.7	-2.7	-3.6	-3.6	-2.7	-3.1	-3.7	-3.5	-3.0
Tense / ‘highly strung’	5.8	9.7	14.7	-3.5	-3.2	-3.6	-2.2	-2.8	-2.4	-3.2	-3.8	-3.2	-1.4	-1.7	-3.3	-3.5	-3.7	-3.1	-2.7	-3.2	-3.8	-3.2
High blood pressure (mother)	4.3	6.0	9.5	2.6	2.6	2.5	0.7	2.8	1.7	2.0	3.1	2.7	1.9	2.6	2.2	2.5	2.7	2.6	2.5	2.1	3.1	2.5
Alcohol drinker status: Previous	4.0	4.6	7.7	-2.5	-1.9	-1.9	-2.6	-1.9	-1.2	-1.8	-2.2	-1.9	1.2	-2.3	-2.0	-2.7	-1.9	-2.5	-2.3	-2.8	-2.5	-1.8
Overall health rating	3.6	7.8	15.8	-3.1	-1.5	-2.9	-3.1	-3.1	-1.9	-3.3	-2.4	-2.4	-0.2	-3.2	-0.9	-3.2	-3.3	-2.7	-4.0	-3.2	-3.2	-2.6
Osteoporosis (self-reported)	3.6	4.5	8.8	2.8	2.2	2.4	0.9	1.7	1.5	1.3	2.2	2.6	-0.3	1.1	2.4	2.6	1.9	3.0	2.4	1.9	2.8	2.0
Long-standing illness, disability or infirmity	3.5	5.4	9.6	-2.9	-1.6	-2.4	-2.6	-2.2	-1.6	-2.2	-2.4	-1.8	-1.4	-2.1	-1.3	-2.9	-3.1	-1.9	-2.5	-2.8	-2.7	-2.5
Mother’s age at death	3.5	4.4	8.8	1.9	3.0	2.7	2.9	2.1	2.3	1.2	2.6	2.1	-1.1	1.2	1.6	2.1	2.1	2.3	1.5	1.8	2.6	1.7
Mood swings	3.3	6.0	9.9	-2.4	-2.5	-2.8	-2.8	-2.4	-1.3	-2.9	-2.8	-2.3	-0.3	-1.4	-0.5	-3.1	-2.9	-2.4	-2.1	-3.1	-3.1	-2.8
Worry (Nagel 2018)	3.1	6.5	11.2	-2.7	-2.9	-2.7	-2.7	-2.6	-2.1	-1.6	-3.1	-2.3	-1.6	-1.4	-3.0	-3.0	-3.4	-1.9	-1.3	-2.6	-3.3	-2.6
Pulse rate, automated reading	3.1	10.0	19.2	-3.8	-3.1	-3.0	-0.7	-3.3	-1.8	-1.9	-3.7	-3.0	-2.6	-2.2	-4.4	-3.6	-3.7	-3.6	-3.4	-2.8	-3.9	-3.5
Age when periods started (menarche)	3.0	7.3	13.5	-2.6	-3.3	-2.1	-0.9	-3.0	-2.8	-2.0	-3.2	-2.4	-1.6	-2.6	-3.7	-2.9	-2.4	-3.0	-2.5	-2.9	-3.2	-2.8
Depression (self-reported)	3.0	3.5	7.8	-2.3	-1.7	-1.8	-1.4	-1.5	-0.1	-1.5	-2.3	-2.8	-0.8	-2.8	-0.5	-2.1	-2.0	-1.8	-1.4	-2.0	-2.2	-2.2
Chronic bronchitis/emphysema (mother)	3.0	3.5	7.8	1.9	2.8	2.3	2.0	1.9	1.9	2.0	2.6	1.7	1.2	0.1	1.4	1.6	1.7	2.2	0.9	1.1	2.2	1.7
Eye problems/disorders: None of the above	3.0	3.5	9.1	1.3	2.2	1.6	3.0	2.9	2.1	1.3	2.3	1.1	-0.1	0.7	1.2	1.8	1.6	2.0	1.8	1.7	2.4	1.9
Age at last live birth	2.9	4.2	9.1	-1.8	-2.1	-2.1	-2.4	-2.5	-1.8	-0.3	-2.0	-1.8	0.1	-1.5	-3.0	-2.4	-1.8	-2.1	-1.9	-2.8	-2.5	-1.3
Taking other prescription medications	2.7	4.2	8.1	-2.4	-1.8	-2.8	-1.5	-2.3	-1.6	-1.7	-2.1	-2.4	-0.7	-2.1	-1.1	-2.2	-2.2	-2.1	-2.7	-2.2	-2.3	-1.5
Medication: Atenolol	2.7	3.4	8.6	-1.2	-1.2	-1.9	-2.9	-2.8	-1.5	0.0	-1.4	-0.2	0.6	-1.0	-2.3	-2.5	-2.2	-1.6	-2.5	-2.6	-1.9	-1.2
Financial difficulties in last 2 years	2.7	3.6	8.2	-1.9	-2.3	-1.7	-0.8	-1.3	-2.4	-1.0	-2.3	-1.8	0.5	-1.4	-0.4	-2.6	-2.9	-1.5	-1.7	-2.5	-2.5	-2.1
Medication: Lansoprazole	2.7	3.1	8.5	-2.6	-0.6	-0.3	-0.3	-1.4	-0.2	-1.4	-1.2	-1.0	-1.5	-2.4	-1.9	-2.3	-1.7	-2.0	-2.9	-2.6	-1.8	-1.9
Eye problems/disorders: Diabetes related eye disease	2.6	2.9	9.7	-1.9	-2.2	-3.1	-2.5	-2.2	-1.6	-0.0	-1.9	-0.8	0.9	0.1	-0.8	-1.2	-0.8	-2.2	-1.9	-1.6	-2.1	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	3.9	9.3	-2.6	-2.0	-1.7	-1.6	-1.2	-1.3	-3.0	-2.2	-2.1	-1.1	-1.9	-1.3	-2.5	-2.8	-1.1	-1.2	-2.4	-2.2	-1.6
Commuting to job workplace: Cycle	2.5	3.0	10.4	1.9	1.4	1.2	0.7	1.9	1.8	3.2	1.8	2.3	1.1	1.6	2.6	1.4	1.6	1.4	1.2	1.4	1.7	0.9
Neuroticism	2.4	5.7	11.0	-2.5	-3.0	-3.3	-2.6	-2.3	-2.1	-1.5	-3.0	-2.2	-0.3	-0.6	-1.8	-3.0	-2.9	-2.2	-1.8	-2.5	-3.1	-2.2
Serious illness, injury or assault to yourself	2.4	2.9	5.8	-2.0	-0.8	-1.1	-1.3	-2.3	-0.7	-0.9	-1.3	-0.8	-1.8	-1.1	-1.7	-2.1	-2.2	-1.9	-2.2	-1.3	-2.2	-2.4
Medication: Atorvastatin	2.4	2.9	13.7	-1.7	-2.5	-1.9	-3.7	-1.6	-1.2	-0.4	-2.1	-0.5	1.1	0.5	-0.6	-1.6	-1.9	-1.4	-1.2	-1.4	-2.2	-1.4
Number of children fathered	2.3	2.6	5.7	1.7	1.1	1.2	-0.4	0.9	0.5	1.6	1.6	1.7	2.3	1.9	2.4	2.1	1.4	1.5	0.9	2.3	1.7	1.7
Medication: Metformin	2.2	3.1	8.2	-2.2	-2.3	-1.7	-2.2	-1.3	-1.0	0.1	-2.2	-1.5	-0.6	-0.4	-2.9	-1.7	-1.3	-2.3	-1.4	-1.6	-2.4	-1.8
Nervous feelings	2.2	4.0	8.1	-2.1	-2.5	-2.0	-2.4	-2.4	-1.5	-0.8	-2.5	-1.4	-0.5	-1.4	-2.4	-2.2	-1.6	-2.1	-1.5	-2.9	-2.5	-1.2
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.6	6.8	0.7	2.2	2.5	2.6	2.3	1.9	0.5	1.7	0.8	-1.4	0.6	1.1	1.4	1.1	1.8	1.7	1.5	1.5	0.7
Suffer from ‘nerves’	2.2	3.5	6.0	-2.2	-2.3	-2.4	-2.2	-1.9	-1.0	-0.6	-2.3	-1.9	-1.2	-1.4	-1.3	-2.2	-2.4	-1.4	-1.1	-2.2	-2.4	-1.5
Hearing aid user	2.1	2.4	4.5	-2.0	-2.0	-1.6	-1.5	-1.8	-0.3	-0.8	-2.1	-1.2	0.2	-1.0	-1.1	-2.0	-1.8	-1.7	-0.9	-1.6	-2.1	-1.7
Illnesses of siblings	2.0	2.8	7.2	-1.7	-1.3	-0.8	-2.2	-1.8	-0.5	-1.1	-1.7	-1.8	-0.2	-1.8	-2.7	-2.1	-2.2	-1.4	-1.4	-1.3	-1.7	-2.0
Worrier / anxious feelings	2.0	3.8	9.5	-1.9	-2.3	-3.1	-2.1	-1.7	-1.3	-1.1	-2.4	-1.9	0.1	-1.9	-1.0	-2.4	-2.7	-1.7	-1.3	-1.5	-2.5	-2.0
Illnesses of mother	2.0	2.5	5.7	-2.0	-1.5	-0.3	-1.2	-2.4	-0.3	-1.0	-1.9	-1.1	-1.2	-1.2	-1.6	-1.6	-1.3	-2.4	-1.8	-1.0	-1.9	-2.0
Illnesses of siblings: Diabetes	2.0	2.5	7.7	2.0	-0.0	-0.0	1.2	1.5	0.6	2.8	0.8	1.5	1.6	2.7	1.9	1.7	1.8	1.1	1.6	1.5	1.0	1.7
Pain experienced in last month	2.0	3.4	5.2	2.3	2.0	1.8	0.3	1.5	2.0	1.7	2.3	2.2	1.7	1.8	1.9	1.5	1.8	2.0	2.3	1.2	2.0	1.4
Crohns Disease (2017)	1.9	4.2	18.8	-2.7	-1.9	-2.3	-0.6	-1.7	-0.6	-1.0	-2.5	-1.7	0.1	-4.3	-0.4	-2.3	-1.7	-2.3	-1.3	-2.3	-2.4	-2.0
Irritable Bowel Disease (IBD)	1.9	4.6	13.8	-2.9	-2.3	-2.7	-1.0	-1.4	-1.1	-1.6	-2.8	-1.7	-0.0	-3.7	-0.9	-2.5	-1.9	-2.2	-0.6	-2.2	-2.6	-2.5
Diverticular disease/diverticulitis (self-reported)	1.9	2.3	6.2	2.3	1.2	0.5	-0.3	-0.8	-0.5	1.8	1.9	1.8	1.6	-0.3	1.4	1.7	1.9	1.9	1.4	0.8	1.6	2.5
Pulse wave Arterial Stiffness index	1.9	2.3	8.8	-1.2	-1.8	-1.8	-0.9	-1.0	-3.0	-2.2	-2.0	-2.3	-1.1	-1.0	-1.9	-0.2	-1.0	-0.6	-0.8	-1.2	-1.0	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	5.5	-1.2	-1.3	-1.1	-1.6	-2.0	-1.3	-2.1	-1.5	-1.5	-1.7	-1.1	-2.3	-1.8	-2.1	-0.9	-0.7	-1.1	-1.8	-1.5
Hearing difficulty/problems with background noise	1.8	2.9	7.0	1.0	2.4	0.3	-0.4	0.2	2.2	1.6	2.4	2.5	2.4	-0.9	2.6	1.3	2.2	1.0	-0.0	0.8	1.9	2.1
Happiness	1.8	2.2	3.9	-1.3	-1.7	-2.0	-1.4	-1.6	-0.8	-1.0	-1.6	-1.9	-0.1	-1.4	-1.7	-1.5	-1.2	-1.9	-1.6	-1.6	-1.7	-1.3
Neuroticism score	1.7	3.6	9.0	-1.9	-2.4	-3.0	-2.6	-1.8	-1.3	-0.8	-2.3	-1.5	0.8	-1.1	-0.8	-2.4	-2.2	-1.4	-1.2	-2.6	-2.4	-1.2
Miserableness	1.7	2.9	7.8	-1.9	-0.6	-1.5	-2.8	-2.2	-0.2	-2.1	-1.3	-1.4	-0.2	-1.3	-0.2	-2.5	-2.3	-1.3	-2.1	-2.2	-1.6	-1.3
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.8	-1.4	-1.2	-0.8	-0.4	-0.9	0.0	0.2	-1.5	-1.0	-0.1	-1.3	-1.9	-2.0	-1.6	-1.6	-1.8	-1.7	-1.7	-1.5
Number of incorrect matches in round	1.6	2.6	6.1	2.2	0.8	1.2	0.9	1.2	0.8	1.1	1.4	2.1	0.7	1.1	2.3	2.2	1.7	2.3	1.6	1.2	1.7	2.5
Hair/balding pattern: Pattern 2	1.6	2.0	9.1	-1.7	-1.0	-1.1	-3.0	-1.0	-0.2	-0.5	-1.2	-1.8	0.9	-0.9	-1.0	-1.8	-1.5	-1.4	-1.1	-1.1	-1.7	-1.5
Alcohol intake versus 10 years previously	1.6	2.4	6.2	-1.8	-1.5	-1.6	-0.4	-2.1	-1.7	-1.3	-1.7	-1.7	-0.7	-1.2	-1.0	-1.4	-1.1	-2.5	-2.0	-0.6	-1.8	-1.9
Crohns Disease (2012)	1.5	2.4	10.8	-2.2	-1.4	-1.8	0.4	-0.9	-0.3	-1.3	-2.0	-1.5	-0.6	-3.3	-0.6	-1.6	-1.2	-2.0	-0.9	-1.3	-1.6	-1.6
LDL Cholesterol	1.5	2.3	5.3	-1.8	-1.7	-0.8	0.7	-0.1	-0.5	-1.4	-1.9	-2.0	-1.6	-0.8	-2.3	-1.6	-1.3	-2.0	-1.2	-1.2	-1.7	-2.0
Bipolar Disorder (2018)	1.4	2.3	6.9	-1.7	-1.1	-0.9	-2.6	-1.5	0.2	-1.1	-1.7	-1.0	-1.2	-2.0	-1.6	-1.5	-1.1	-1.5	-1.7	-2.3	-1.2	-1.2
Breast Cancer	1.4	3.3	10.2	1.9	2.4	3.2	1.0	1.2	1.6	0.1	1.9	1.2	-1.0	0.2	1.6	2.3	2.3	2.0	1.5	1.2	2.8	1.9
Lupus	1.4	2.2	4.5	-1.3	-1.6	-1.7	-1.1	-2.1	-1.8	-1.4	-1.8	-1.6	-0.8	-0.9	0.1	-1.3	-1.9	-1.7	-1.9	-0.7	-1.6	-1.2
Supplements: Zinc	1.4	1.5	4.7	-1.4	-1.0	-0.3	2.0	-0.1	-0.4	-1.2	-1.3	-2.2	-1.1	-0.1	-0.8	-1.2	-1.7	-1.0	-0.9	-0.4	-1.5	-1.8
Qualifications: CSEs or equivalent	1.4	1.9	4.7	1.3	1.3	1.6	0.5	1.4	0.9	2.2	1.6	1.4	1.4	1.9	1.3	1.0	1.6	0.9	1.4	1.4	1.3	0.8
Mouth/teeth dental problems: Dentures	1.4	2.4	7.0	-1.4	-1.9	-1.9	-0.9	-1.7	-2.7	-0.8	-1.7	-1.3	0.9	-1.5	-1.8	-1.0	-0.3	-2.0	-1.8	-1.6	-1.6	0.1
Exposure to tobacco smoke at home	1.4	1.5	3.4	1.6	1.5	1.1	0.7	0.5	0.4	1.8	1.5	1.3	-0.0	1.8	0.7	1.4	0.8	1.5	0.6	1.6	1.4	1.0
Birth weight of first child	1.4	2.6	5.2	2.1	1.2	1.2	1.3	1.7	0.5	1.6	1.6	1.8	1.3	2.3	1.1	1.5	1.4	1.9	2.3	1.9	1.5	1.3
Pulse wave peak to peak time	1.4	1.6	6.5	1.0	1.6	1.5	0.8	0.7	2.6	1.9	1.8	1.8	1.0	0.7	1.3	0.3	1.1	0.3	0.5	1.2	0.9	0.2
Angina (self-reported)	1.4	1.8	8.4	-0.6	-0.7	-0.9	-2.9	-2.4	-1.1	0.4	-0.4	0.6	1.2	-0.5	-0.7	-1.6	-1.6	-1.1	-2.1	-1.2	-1.4	-0.2
Medication: Seretide 50 evohaler	1.4	1.6	4.0	-1.0	-1.0	-0.4	-0.9	-1.1	-0.4	-1.6	-1.4	-1.3	-0.6	-1.9	-1.9	-1.3	-1.3	-1.0	-1.6	-2.0	-1.0	-0.7
Leg pain on walking	1.4	1.8	3.4	-1.7	-1.1	-1.9	-0.8	-1.1	-1.0	-0.7	-1.6	-1.0	-0.1	-1.0	-1.6	-1.5	-1.4	-1.5	-1.6	-1.3	-1.8	-1.4
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	13.0	0.7	-0.4	-1.8	-2.0	-0.2	-0.4	1.7	0.7	0.4	3.6	0.6	0.1	0.5	1.7	-0.4	-0.4	0.2	0.1	1.9
Neuroticism (Nagel 2018)	1.3	3.1	7.7	-2.0	-1.6	-1.6	-2.7	-1.7	-0.8	-0.9	-2.0	-1.0	-0.9	-0.6	-1.1	-2.6	-2.8	-1.0	-1.1	-2.4	-2.3	-2.0
Fasting Glucose	1.3	1.5	4.6	-1.5	-1.5	-1.6	-0.3	-0.8	-0.8	0.2	-1.7	0.2	-0.2	-0.5	-2.0	-1.1	-0.7	-1.5	-1.0	-1.7	-2.1	-1.0
Angina	1.3	1.8	8.2	-0.6	-0.5	-0.7	-2.9	-2.5	-0.8	0.2	-0.3	0.6	1.0	-0.7	-0.9	-1.7	-1.7	-1.1	-2.2	-1.2	-1.4	-0.4
Mouth/teeth dental problems	1.3	2.0	7.4	1.2	1.4	1.2	1.1	1.5	2.7	1.5	1.4	1.4	1.0	0.8	2.7	0.6	0.7	1.2	1.5	0.9	1.2	-0.1
Breastfed as a baby	1.3	1.6	7.5	-1.4	-1.3	-1.7	-0.7	-1.5	-0.8	-0.9	-1.5	-1.0	-2.7	-1.5	-1.4	-0.5	-0.6	-1.1	-1.1	-1.0	-0.8	-0.7
Medication: Amlodipine	1.3	1.8	4.2	1.4	0.9	0.1	0.4	1.2	1.2	2.0	1.4	1.3	0.7	1.9	1.3	1.6	2.0	0.9	1.0	1.0	1.2	1.6
Forced vital capacity (FVC), Best measure	1.3	4.9	10.6	-1.8	-2.0	-0.5	-2.2	-2.7	-1.9	-3.1	-2.2	-2.0	-2.1	-0.8	-3.3	-2.6	-2.3	-2.5	-1.8	-1.5	-2.2	-2.6
Exposure to tobacco smoke outside home	1.3	1.7	5.6	-1.3	-0.8	-0.9	-0.8	-1.8	-0.6	-1.2	-1.2	0.0	0.2	-0.4	1.0	-1.6	-1.3	-1.9	-2.4	-1.7	-1.5	-1.6
Chest pain or discomfort	1.3	1.9	6.2	-1.6	-0.7	-1.6	-1.1	-1.2	-1.1	-0.3	-1.0	-1.0	0.3	-1.6	-0.8	-1.9	-2.5	-0.7	-2.1	-1.6	-1.7	-0.8
Eye problems/disorders: Cataract	1.3	1.4	3.8	-1.0	-1.8	-1.1	-1.9	-1.2	-1.4	-0.6	-1.7	-0.9	0.0	-0.5	-1.1	-1.1	-1.4	-0.9	-0.5	-1.1	-1.6	-1.3
Medication: Gliclazide	1.3	1.5	4.5	-1.5	-1.4	-1.0	-0.7	-0.9	-0.4	0.5	-1.4	-0.6	-0.8	0.1	-1.4	-1.4	-0.9	-2.1	-1.7	-1.4	-1.6	-1.5
Age started oral contraceptive pill	1.3	1.6	4.1	-1.1	-1.3	-1.3	-1.0	-1.2	-1.4	-1.0	-1.3	-1.9	-1.0	-2.0	-1.6	-0.8	-1.1	-0.6	-1.1	-1.6	-1.2	-0.1
Unable to work because of sickness or disability	1.3	1.7	6.0	-0.6	-0.7	-0.4	-0.9	-1.9	-2.5	-1.7	-1.1	-1.3	-1.3	-1.0	-1.6	-1.1	-1.8	-0.6	-1.4	-1.0	-1.3	-0.7
Hand grip strength (right)	1.2	3.2	5.2	-1.8	-1.9	-0.5	-1.2	-2.1	-1.1	-1.6	-2.3	-1.5	-1.9	-0.9	-2.3	-1.9	-1.6	-2.0	-1.4	-2.3	-2.1	-2.3
Alcohol usually taken with meals	1.2	2.0	5.2	0.6	1.8	1.7	2.1	1.2	1.8	0.9	1.6	1.8	-0.7	0.2	1.7	1.7	2.3	0.8	0.3	0.3	1.5	1.0
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	3.8	1.4	0.3	0.4	1.8	1.7	-0.1	1.6	0.8	0.5	0.3	2.0	1.2	1.0	0.9	1.6	2.0	1.2	0.9	1.1
Medication: Simvastatin	1.2	1.8	4.8	2.1	1.0	-0.3	1.1	0.7	0.5	1.8	1.6	1.1	0.9	1.1	0.7	1.6	2.2	0.6	0.5	0.8	1.7	2.2
Prospective memory result	1.2	1.5	6.3	1.6	-0.7	0.8	1.4	0.3	-0.4	1.5	0.4	2.5	1.2	1.8	0.9	1.1	1.5	0.4	1.0	0.8	0.6	1.7
Glaucoma (self-reported)	1.2	1.5	4.4	-0.6	-1.6	-1.4	-0.9	-1.3	-0.9	-0.6	-1.3	-1.7	0.8	-0.1	-0.3	-1.4	-0.6	-2.1	-1.0	-0.4	-1.5	-1.9
Medication: Ventolin 100micrograms inhaler	1.2	1.5	7.5	-1.2	-1.3	-2.7	0.3	-0.2	-0.6	0.9	-1.0	-1.7	0.8	-0.4	0.2	-1.4	-1.2	-1.3	-1.4	-0.9	-1.4	-1.1
Eye problems/disorders: Glaucoma	1.2	1.4	4.1	-0.7	-1.3	-1.4	-0.8	-1.3	-0.8	-0.5	-1.2	-1.2	0.7	-0.5	-0.9	-1.4	-0.6	-2.0	-1.4	-1.0	-1.5	-1.6
Alzheimer’s Disease (in mother)	1.1	1.3	3.1	-0.6	-1.2	-1.6	0.2	-0.4	-1.8	-1.6	-0.9	-1.7	-0.7	-0.9	-1.6	-1.1	-1.4	-0.6	-0.5	-0.5	-1.3	-1.2
Chronotype (morning person)	1.1	2.5	5.8	1.5	2.4	1.0	-0.2	1.4	2.3	1.3	2.4	2.1	0.2	-0.1	1.4	1.8	2.3	1.1	0.7	1.0	2.3	1.4
Sitting height	1.1	7.5	11.4	-3.0	-2.5	-2.3	-3.2	-3.3	-1.9	-3.3	-2.8	-3.0	-0.9	-1.9	-2.9	-3.2	-2.5	-3.4	-2.3	-2.1	-3.0	-2.9
Had menopause	1.1	1.3	9.1	0.8	1.3	0.7	0.9	1.4	1.5	0.7	1.1	1.0	0.3	0.6	3.0	1.0	1.1	0.6	0.5	0.7	1.1	0.9
Breast cancer (self-reported)	1.1	1.3	3.7	-0.9	-0.6	-0.1	-0.8	-1.6	-0.5	0.3	-0.9	-0.5	-0.4	-1.0	-1.8	-1.9	-1.7	-1.1	-1.1	-1.4	-1.3	-1.3
Average weekly beer plus cider intake	1.1	1.6	5.9	2.1	0.8	1.4	-0.3	-0.3	-0.2	1.4	1.2	1.1	0.1	2.4	0.6	1.3	1.4	1.2	1.3	1.2	1.4	1.1
Depressed Affect (Nagel 2018)	1.0	2.2	7.8	-1.2	-0.7	-1.0	-2.8	-2.0	0.0	-1.6	-1.4	-0.5	-0.5	-0.1	0.5	-2.1	-2.3	-0.6	-1.0	-2.0	-1.6	-1.9
Waist Hip Ratio (WHR)	1.0	4.7	16.6	1.3	1.5	0.9	-2.9	2.0	1.7	3.1	1.4	3.0	4.1	3.4	-0.7	1.4	1.2	2.0	2.1	1.7	1.6	1.3
Hand grip strength (left)	1.0	2.6	5.3	-1.3	-2.0	-0.9	-0.3	-1.3	-1.3	-1.5	-2.1	-2.1	-1.8	-1.1	-2.3	-1.7	-1.5	-1.7	-0.7	-1.6	-1.9	-2.0
Hearing difficulty/problems: Yes	1.0	1.5	8.2	-0.8	-0.2	-1.6	-2.5	-1.8	0.3	0.4	0.0	0.3	2.9	-0.8	1.3	-0.9	-0.3	-0.7	-1.3	-1.0	-0.7	0.5
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	3.3	-1.3	-1.1	-1.3	-0.6	-0.9	-1.2	-0.2	-1.2	-0.5	0.3	-0.2	-1.1	-1.8	-1.5	-1.2	-1.2	-1.2	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	8.9	-1.2	-1.9	0.3	-1.8	-1.8	-1.3	-2.5	-2.0	-1.1	-1.8	-0.2	-3.0	-2.2	-2.1	-1.6	-0.6	-1.2	-1.8	-2.4
Alcohol intake frequency.	1.0	2.2	5.3	-1.3	-1.9	-2.0	-1.7	-2.3	-2.3	-0.8	-1.6	-1.1	1.1	-0.8	0.1	-1.0	-1.5	-1.2	-1.6	-1.5	-1.8	-0.6
Ever taken oral contraceptive pill	1.0	1.1	5.4	-0.7	1.7	2.2	0.6	0.1	1.0	-1.5	0.8	0.8	-2.3	-0.6	-0.0	-0.1	-0.5	0.6	-0.4	0.1	0.6	-0.5
Coronary Artery Disease (CAD)	0.9	1.1	3.2	-1.1	-1.0	-1.3	-0.1	-0.8	-0.2	0.1	-1.0	-0.6	0.1	-0.6	-1.1	-1.3	-0.6	-1.6	-1.8	-1.7	-1.2	-0.5
Triglycerides	0.9	1.4	3.8	2.0	0.7	1.4	0.3	0.9	0.7	1.4	1.4	1.7	0.1	1.3	0.4	1.1	1.0	1.8	1.2	0.4	1.0	1.6
Blood Red Count	0.9	8.3	41.5	0.9	-2.5	-1.6	4.8	6.4	1.0	-0.1	-1.1	-3.8	-0.4	3.7	4.2	0.6	-0.2	1.1	4.9	2.7	-0.3	-1.4
Medication for hormone replacement therapy	0.9	1.0	6.0	-0.2	1.2	1.1	-0.1	1.3	2.0	-0.2	0.8	0.8	0.5	1.2	2.5	0.0	0.1	0.4	0.8	0.8	0.7	-0.3
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	3.6	1.1	1.9	1.8	0.6	0.4	0.8	0.2	1.5	1.1	-0.1	0.0	0.4	-0.1	-0.5	1.6	0.7	0.1	1.0	0.0
Trunk fat mass	0.9	3.7	13.0	-1.7	-2.6	-3.6	-1.7	-1.1	-2.4	-1.3	-2.3	-1.6	3.1	-1.3	2.0	-1.2	-0.7	-2.2	-1.1	-0.9	-1.9	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	5.7	-1.1	-1.5	-2.4	0.5	-1.0	-1.3	-0.0	-1.3	-1.2	0.1	-1.2	-1.9	-1.0	-0.9	-1.0	-1.2	-1.0	-1.3	-0.5
Heart attack	0.9	1.1	5.4	1.2	-0.2	-0.8	-0.8	-0.2	-1.0	1.6	0.7	1.6	2.3	2.2	0.3	0.2	0.3	0.1	-0.0	1.1	-0.3	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	4.0	-1.3	-0.0	-0.3	-1.3	-0.8	0.9	-0.9	-0.8	-1.0	-0.7	-2.0	-0.0	-1.9	-1.8	-0.3	-1.0	-1.7	-1.2	-1.7
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	7.2	-0.9	0.1	0.4	-0.1	-0.5	-1.1	-2.1	-0.6	-0.4	-2.6	0.0	-2.7	0.1	-0.7	0.3	-0.4	-0.2	-0.2	0.1
Age at first live birth	0.9	1.5	7.4	-0.9	-0.5	-0.9	-0.7	-1.7	-0.8	0.0	-0.8	-1.2	-0.4	-1.7	-2.7	-1.1	-0.4	-1.5	-1.4	-1.6	-1.3	-0.8
Illnesses of father: Heart disease	0.9	1.2	3.9	-1.2	-0.4	-0.2	-0.9	-0.9	-0.1	-0.2	-0.5	0.1	0.1	-1.0	-0.6	-1.8	-1.4	-1.3	-2.0	-1.6	-1.5	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	10.3	-1.0	-0.3	0.1	-1.3	-1.4	-1.0	-3.2	-0.8	-0.8	-0.9	-0.6	-2.1	-1.5	-1.6	-0.9	-0.9	-0.9	-1.1	-1.5
Number of self-reported non-cancer illnesses	0.9	1.5	7.0	-1.9	-1.2	-2.6	-0.6	-0.1	-0.4	-0.2	-1.4	-1.2	0.5	-1.2	1.1	-1.3	-1.1	-1.1	-0.9	-1.4	-1.4	-1.0
Financial situation satisfaction	0.9	1.1	3.9	-0.3	-1.4	-2.0	0.4	-1.5	-1.1	-1.2	-1.0	-1.4	0.1	-0.4	-0.2	-0.9	-1.0	-1.2	-1.1	-0.4	-1.3	-0.3
Fractured/broken bones in last 5 years	0.9	1.2	5.7	0.3	1.4	1.5	-2.4	-1.3	0.2	-0.4	0.6	2.2	0.5	-0.2	1.1	-0.1	-0.6	1.2	-0.2	-1.3	0.6	0.2
Ulcerative Colitis (UC)	0.8	1.4	3.4	-1.6	-1.6	-1.8	-0.8	-0.2	-0.6	-1.0	-1.7	-0.7	0.2	-1.6	-0.4	-1.4	-1.0	-1.1	0.5	-0.9	-1.4	-1.8
Major Depression (MDD)	0.8	0.9	3.2	-0.6	0.6	0.0	-0.1	-1.3	-0.9	-1.8	-0.2	-1.8	-0.3	-1.6	-0.4	-0.8	-1.1	-0.3	-1.5	-0.6	-0.3	-0.8
Prostate Cancer	0.8	1.2	3.3	-1.3	-0.8	-1.0	-0.6	-0.3	-0.9	-1.1	-0.9	-1.3	-0.1	-0.5	-0.9	-1.1	-0.4	-1.7	-1.8	-1.7	-1.1	-0.8
Blood Platelet Count	0.8	9.2	37.0	-1.7	-2.8	-3.2	-5.5	-6.1	-4.1	-0.6	-2.9	0.2	1.5	-3.0	-1.9	-2.3	-2.2	-1.7	-2.6	-4.4	-2.5	-0.6
Ever used hormone-replacement therapy (HRT)	0.8	1.0	6.4	-0.3	0.8	0.3	1.4	0.8	1.5	-0.9	0.6	0.3	-0.8	0.5	2.5	0.9	1.0	-0.1	0.2	1.0	1.1	0.6
Trunk fat percentage	0.8	3.4	14.7	-1.3	-2.3	-3.5	-1.4	-0.6	-2.2	-1.2	-2.0	-1.3	3.8	-1.4	2.8	-0.8	-0.5	-1.5	-0.6	-0.7	-1.5	-0.2
Qualifications: None of the above	0.8	1.6	5.9	-0.9	-2.4	-1.8	-0.4	-0.3	-2.3	-0.2	-1.9	-1.0	1.8	0.4	1.2	-0.4	-0.8	-1.4	-0.6	-0.6	-1.4	-0.6
Pulse rate	0.8	1.3	7.1	-0.7	-0.6	-0.3	-1.1	-2.0	-1.9	-1.4	-1.0	-0.4	-1.2	-0.8	-2.7	-0.3	-0.6	-0.5	-1.1	-0.8	-0.7	-0.1
Comparative body size at age 10	0.8	2.2	8.5	1.1	1.0	0.5	-0.8	1.3	0.8	1.4	1.4	1.3	2.9	1.7	1.5	1.8	2.3	0.2	0.9	1.9	1.4	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.3	1.5	0.7	-0.3	-0.2	0.3	0.5	1.5	1.2	1.0	0.7	1.5	1.0	1.0	1.2	0.5	0.4	0.7	1.2	1.2
Knee pain experienced in last month	0.8	1.2	3.9	-2.0	-1.5	-0.7	-0.3	-0.1	-1.3	-0.8	-1.9	-1.3	-1.3	-0.7	-0.7	-0.5	-0.8	-0.8	-0.2	-0.9	-1.2	-1.3
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.3	-1.5	-0.5	-0.9	-0.4	-0.6	-1.3	-1.5	-1.1	-1.3	-1.2	-1.4	-0.8	-0.5	-0.7	-0.8	-1.2	-0.7	-0.7	-0.5
Ever had prostate specific antigen (PSA) test	0.8	0.9	5.7	0.5	1.3	0.7	-0.7	-0.4	1.1	0.8	1.4	0.9	0.8	-0.0	2.4	0.6	0.8	0.8	0.5	0.8	1.0	0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.0	4.8	1.0	-0.4	-0.9	-0.8	-0.3	-1.2	1.5	0.6	1.4	2.2	2.1	0.1	-0.1	0.0	-0.1	-0.3	0.8	-0.5	0.2
Depression (Nagel 2018)	0.7	1.0	3.5	-0.9	0.4	0.2	-0.6	-1.0	0.8	-0.9	-0.4	0.3	-1.2	-0.8	-0.2	-1.8	-1.9	-0.1	-0.6	-1.5	-0.9	-1.7
Mean Putamen Volume	0.7	0.8	2.0	-1.2	-1.4	-0.5	-0.9	-0.4	-1.2	-0.4	-1.4	-1.3	0.0	-0.6	-0.7	-0.7	-0.3	-1.0	-0.3	-1.1	-1.3	-0.8
HDL Cholesterol	0.7	1.1	5.2	-0.9	-0.3	-1.1	-1.2	-1.6	-1.1	-1.2	-0.6	-0.8	1.3	-2.3	-0.4	-0.3	-0.1	-1.2	-1.3	-0.9	-0.3	0.4
Blood White Count	0.7	5.5	13.0	-0.8	-3.4	-2.9	-2.2	-3.6	-3.3	0.4	-2.7	-1.4	-0.9	1.1	-2.5	-2.3	-2.7	-2.0	-1.9	-2.0	-3.0	-2.1
Frequency of depressed mood in last 2 weeks	0.7	0.9	2.6	-1.1	-0.6	-1.0	-1.0	-1.0	-0.5	-1.0	-1.0	-1.1	0.2	-1.2	-0.1	-1.2	-1.6	-0.4	-0.9	-0.9	-1.1	-1.2
Diabetes (father)	0.7	0.9	6.6	-0.2	0.9	0.6	2.6	1.4	1.9	0.9	0.6	0.1	-0.9	-1.1	-0.0	-0.1	0.5	-0.0	0.4	-0.1	0.4	-0.2
Average weekly fortified wine intake	0.7	0.8	2.2	1.4	0.7	1.0	0.2	0.9	0.4	0.2	0.9	0.9	0.6	0.4	-0.5	1.5	1.5	1.0	0.6	0.5	1.1	1.5
Forced vital capacity (FVC)	0.7	2.7	8.2	-1.2	-1.4	-0.1	-0.9	-1.7	-1.6	-2.9	-1.6	-1.8	-2.3	-0.1	-2.5	-1.7	-1.5	-1.9	-1.1	-0.7	-1.4	-2.0
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	5.9	-0.5	-1.0	-0.8	0.4	0.1	-0.8	-1.3	-0.8	-2.4	0.2	-0.1	-1.3	-1.0	-0.9	-0.9	0.0	-0.3	-1.0	-0.8
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	6.1	0.7	1.2	2.0	0.8	1.1	2.5	1.4	1.3	0.6	-0.1	0.4	0.3	0.0	0.6	0.5	1.1	1.0	0.8	-0.3
Birth weight	0.7	1.5	8.6	0.7	0.3	0.9	0.5	1.5	0.5	1.0	0.7	1.8	1.6	1.4	2.9	0.6	1.0	0.7	1.6	1.3	0.6	0.4
Body fat percentage	0.7	2.9	13.2	-1.1	-2.1	-3.3	-1.2	-0.4	-2.1	-0.9	-1.7	-1.1	3.6	-1.2	3.0	-0.6	-0.5	-1.2	-0.5	-0.5	-1.4	-0.1
Wheeze or whistling in the chest in last year	0.7	1.2	7.8	-0.1	-0.1	-1.9	-2.0	-0.4	-0.5	1.4	0.0	0.7	2.8	-0.6	1.4	-0.2	0.1	-0.3	-1.0	-0.8	-0.3	0.8
Migraine (self-reported)	0.7	0.8	3.7	0.4	-0.7	-0.1	-0.7	1.5	-0.9	-1.2	-0.2	-0.7	1.6	0.7	0.7	0.5	-0.1	1.1	1.9	0.9	0.3	0.5
Medication: Ibuprofen	0.7	0.8	2.2	-0.8	-1.2	-1.1	-0.3	-0.4	-1.4	0.2	-1.1	-0.3	0.1	0.2	-1.1	-1.4	-1.5	-0.5	-0.4	-0.8	-1.2	-1.0
Medication: Allopurinol	0.7	1.0	4.6	0.5	0.7	-1.1	0.7	-0.5	-0.2	0.7	1.0	-0.5	-0.4	-0.1	-1.5	1.0	1.8	-0.6	-1.2	0.3	0.8	2.1
Number of full sisters	0.7	0.8	4.1	0.5	0.5	0.4	0.9	0.8	0.2	1.1	0.7	0.7	1.6	0.9	2.0	0.5	0.4	0.5	1.1	1.4	0.4	-0.1
Back pain experienced in last month	0.7	1.1	3.5	-1.2	-0.5	-0.1	-1.0	-1.7	-1.3	-1.1	-0.8	-0.5	-1.4	-1.2	-0.7	-0.6	-0.9	-0.8	-1.9	-1.0	-0.8	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	5.3	-1.1	-1.3	-0.6	-1.3	-0.8	-0.7	-2.3	-1.3	-1.2	-1.6	-0.5	-2.1	-1.1	-1.2	-1.0	-0.7	-1.0	-0.8	-1.1
Medication: Bendroflumethiazide	0.7	1.0	4.5	-0.4	0.5	-0.8	-2.1	-0.1	1.2	0.8	0.3	1.2	1.2	-1.1	1.3	0.1	1.1	-0.6	-0.8	-1.5	0.5	0.4
Ever smoked	0.7	1.2	8.0	-0.3	1.9	2.8	0.4	0.7	1.7	-0.2	1.3	0.2	0.3	0.6	0.6	-1.2	-0.7	-0.4	-0.6	0.0	0.1	-1.4
Risk taking	0.7	1.0	2.2	0.9	1.0	0.7	0.9	0.6	-0.4	0.8	1.5	1.4	1.3	1.5	0.9	0.9	0.3	1.4	0.1	0.9	0.7	1.2
Heart disease (siblings)	0.7	0.9	2.9	0.4	0.8	0.0	-1.7	-0.5	0.3	1.2	1.0	1.3	1.6	1.0	1.0	0.2	0.7	-0.7	-1.4	0.0	0.2	0.8
Alzheimer’s Disease (in father)	0.6	0.7	2.3	1.2	0.6	-0.2	0.8	-0.5	-0.8	1.3	1.0	1.1	-0.1	1.5	0.4	0.5	0.3	0.3	-0.4	1.1	0.6	0.9
Ovarian Cancer	0.6	0.7	2.4	1.1	0.6	1.0	0.1	-0.1	0.2	0.6	0.7	0.8	1.0	0.6	1.2	1.4	1.5	0.4	0.4	0.7	1.2	0.9
Neuroticism (2016)	0.6	0.9	2.1	-1.1	-0.8	-1.3	-0.9	-0.4	-0.7	-0.9	-1.2	-1.3	-0.7	-0.6	-0.6	-0.9	-1.4	-0.4	-1.2	-0.9	-1.3	-0.7
Height	0.6	11.1	28.0	-2.9	-4.1	-4.2	-4.0	-4.1	-5.3	-4.1	-4.1	-3.4	0.6	-1.9	-3.4	-2.0	-2.1	-3.6	-2.6	-1.6	-3.4	-2.0
Number of treatments/medications taken	0.6	1.1	4.5	-1.4	-0.7	-2.1	-1.3	-0.9	-1.0	-0.7	-0.9	-0.5	0.3	-1.1	0.1	-0.9	-0.6	-0.9	-1.5	-1.5	-0.8	-0.0
Ever had hysterectomy (womb removed)	0.6	0.7	1.5	0.4	0.2	0.0	0.7	1.2	0.5	1.1	0.5	0.9	0.8	1.2	1.1	1.2	1.1	0.6	0.7	0.9	0.9	0.8
Systolic blood pressure, automated reading	0.6	1.8	5.6	1.6	1.3	0.9	0.8	1.1	0.9	0.6	1.3	1.1	0.6	0.7	-0.2	2.1	2.4	1.0	1.2	1.7	1.9	2.0
Maternal smoking around birth	0.6	0.8	3.4	1.0	0.5	0.1	0.6	1.1	-0.2	0.5	0.6	-0.1	0.5	0.2	1.9	0.9	0.7	1.4	1.8	0.3	0.8	1.2
Past tobacco smoking	0.6	1.0	3.4	0.0	-1.8	-1.7	-0.4	-0.5	-1.9	0.2	-1.3	-0.5	-0.8	-0.9	-1.8	1.1	0.6	0.3	0.6	-0.0	-0.4	0.9
Diabetes (self-reported)	0.6	0.9	4.2	-0.7	-1.6	-1.3	-1.0	-0.8	-1.5	0.8	-1.2	-0.4	-0.0	0.5	-2.0	-0.1	-0.1	-0.9	-0.4	-0.3	-1.3	-0.2
Medication: Ramipril	0.6	0.8	1.9	1.4	0.8	-0.2	0.3	0.4	1.0	0.5	1.1	1.3	0.6	1.2	0.4	0.8	1.1	0.6	1.2	1.0	0.7	0.9
Weight	0.6	2.9	7.2	-1.8	-2.6	-2.7	-1.3	-1.7	-2.5	-1.1	-2.3	-1.5	1.3	-0.8	0.4	-1.2	-0.8	-2.4	-1.6	-0.8	-2.0	-1.1
Arm fat percentage (right)	0.6	2.2	13.5	-0.7	-1.8	-2.7	-0.5	0.2	-1.5	-0.3	-1.3	-0.8	3.7	-0.3	3.1	-0.3	-0.1	-1.0	-0.2	-0.1	-1.0	0.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	6.0	-1.0	-1.6	0.5	-1.1	-1.1	-1.0	-2.5	-1.7	-1.1	-1.8	0.2	-2.2	-1.7	-1.6	-1.3	0.0	-0.7	-1.4	-2.1
Standing height	0.6	6.4	13.2	-2.3	-2.4	-2.1	-2.8	-3.6	-3.6	-3.1	-2.6	-2.9	-0.9	-1.6	-3.6	-1.9	-1.7	-2.8	-2.1	-1.2	-2.3	-2.1
Ever highly irritable/argumentative for 2 days	0.6	0.8	2.1	-0.9	-1.0	-0.5	-0.5	0.6	0.1	-0.8	-1.3	-1.0	-1.1	0.7	0.0	-1.1	-1.1	-0.6	-0.0	-1.5	-1.0	-1.3
High blood pressure (siblings)	0.6	0.9	3.7	0.9	0.0	-0.5	1.9	1.1	-0.8	0.1	0.5	0.6	-0.1	1.1	1.2	1.3	1.4	0.4	0.9	0.6	0.8	1.3
Shortness of breath walking on level ground	0.6	0.7	1.8	0.8	1.1	0.7	0.6	1.0	1.1	-0.4	0.7	1.0	-0.2	0.3	0.2	1.1	0.7	1.4	1.1	0.7	0.9	0.8
Whole body fat mass	0.6	2.5	9.5	-1.4	-2.2	-3.1	-1.2	-0.8	-2.2	-0.9	-1.9	-1.3	2.6	-0.8	2.1	-0.8	-0.4	-1.8	-0.8	-0.5	-1.5	-0.5
Family relationship satisfaction	0.6	0.8	3.6	0.0	-0.8	-1.1	-1.7	-1.9	-0.5	-1.0	-0.4	-0.4	0.9	-0.3	-0.3	-0.8	-0.7	-0.5	-0.6	-1.3	-0.7	-0.1
Smoking status: Previous	0.6	0.9	3.6	0.4	1.8	1.0	0.3	0.5	1.7	-0.3	1.5	0.6	1.2	0.6	1.9	-0.6	-0.1	-0.1	-0.5	0.2	0.8	-0.2
Leg fat-free mass (right)	0.6	3.0	8.0	-1.9	-2.6	-1.9	-1.4	-1.7	-1.7	-0.8	-2.5	-1.4	0.4	0.2	-1.1	-1.7	-1.0	-2.8	-1.6	-1.0	-2.3	-1.9
Arm fat percentage (left)	0.6	2.2	15.1	-0.5	-1.7	-2.6	-0.4	0.8	-1.1	0.0	-1.1	-0.5	3.9	0.1	3.5	-0.1	0.2	-0.8	0.1	0.2	-0.8	0.5
Ever had bowel cancer screening	0.6	0.6	3.1	-0.3	-0.9	-1.1	-1.3	-1.6	-1.8	-0.1	-0.6	-0.7	0.3	0.1	-0.5	-0.1	-0.2	-0.6	-0.7	-0.5	-0.7	0.2
Diabetes diagnosed by doctor	0.6	0.9	3.7	-0.8	-1.6	-0.9	-1.0	-0.6	-1.2	0.8	-1.2	-0.2	-0.5	0.8	-1.9	-0.5	-0.4	-1.0	-0.3	-0.5	-1.3	-0.6
Arm fat-free mass (left)	0.6	3.1	6.1	-1.7	-2.3	-1.6	-1.1	-2.5	-2.3	-1.1	-2.3	-1.5	-1.4	-0.4	-1.5	-1.5	-1.3	-2.3	-1.7	-1.0	-2.1	-1.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	6.2	0.7	1.1	0.5	-0.4	0.2	0.1	-0.6	0.7	1.1	0.4	-0.0	2.5	0.7	-0.2	1.6	0.6	0.1	0.8	0.2
Alzheimer’s Disease (including proxy)	0.5	0.7	3.1	0.0	-0.7	-1.4	-0.2	-1.1	-1.8	-0.3	-0.3	-1.0	-0.4	0.1	-1.1	-0.7	-1.0	-0.6	-1.0	0.1	-0.8	-0.6
HbA1C	0.5	0.6	2.4	-0.9	-0.2	0.4	0.9	1.0	0.5	0.4	-0.2	-0.7	-1.5	1.3	-1.4	-0.0	0.2	-0.9	-0.4	0.2	-0.3	-0.8
Type 2 Diabetes (T2D) (2018)	0.5	1.0	4.0	-0.8	-1.4	-1.1	-1.1	-0.6	-0.8	1.1	-1.0	-0.0	-0.6	1.3	-2.0	-0.4	0.0	-1.3	-0.6	-0.9	-1.2	-0.4
Average weekly spirits intake	0.5	0.6	4.8	0.1	0.1	-0.9	-0.6	0.1	0.7	0.5	0.5	0.6	2.2	0.9	1.1	-0.0	0.6	-0.7	-0.4	0.5	0.0	0.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.8	-1.3	0.2	-0.3	-1.3	-0.7	0.2	-0.3	-0.5	0.2	0.1	-0.7	1.2	-1.0	-0.7	-0.8	-0.9	-1.1	-0.7	-1.3
Diabetes (mother)	0.5	0.6	3.2	0.6	-1.0	-0.8	0.3	-0.2	-0.5	1.8	-0.1	0.7	0.9	1.1	1.2	0.4	0.5	0.3	1.0	0.4	-0.0	0.9
Severe depression (siblings)	0.5	0.5	1.3	0.1	-0.1	0.9	1.0	0.9	0.6	-0.3	-0.2	-0.9	-0.7	0.0	0.8	1.0	1.0	0.1	1.1	0.9	0.9	0.1
Leg fat-free mass (left)	0.5	2.6	7.5	-1.7	-2.5	-2.0	-1.4	-1.5	-1.7	-0.9	-2.3	-1.4	0.6	0.1	-0.6	-1.5	-0.8	-2.7	-1.2	-0.7	-2.2	-1.8
Current tobacco smoking	0.5	0.8	1.9	-0.5	-0.7	0.0	-1.2	-0.6	-1.4	-0.7	-0.5	-0.7	0.8	0.4	-0.1	-1.2	-1.2	-0.9	-1.2	-0.3	-1.2	-1.4
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	0.9	1.0	0.8	0.4	0.3	0.5	0.5	0.5	0.9	0.5	0.4	0.8	-0.0	1.0	0.7	0.9	0.8	1.0	1.0	1.0
Leg predicted mass (left)	0.5	2.7	7.6	-1.8	-2.5	-2.1	-1.4	-1.6	-1.7	-1.0	-2.4	-1.4	0.5	0.1	-0.6	-1.6	-0.9	-2.8	-1.3	-0.8	-2.2	-1.9
Trunk fat-free mass	0.5	2.6	5.9	-1.7	-1.9	-1.0	-1.0	-2.4	-1.7	-1.1	-1.9	-1.3	-1.9	0.0	-1.8	-1.5	-1.0	-2.4	-1.7	-0.7	-1.9	-1.9
Falls in the last year	0.5	0.7	5.7	-0.1	-0.0	-0.5	-0.5	0.6	-0.8	1.1	0.3	1.2	2.4	0.3	1.4	0.3	0.4	0.4	-0.6	-0.6	-0.1	0.8
Number of live births	0.5	0.7	2.2	-0.4	-0.9	-1.5	-1.5	-0.9	-1.4	-0.1	-0.7	0.0	1.4	-0.3	-0.5	-0.3	-0.1	-0.6	-0.4	-0.8	-0.5	0.5
Trunk predicted mass	0.5	2.8	6.1	-1.8	-2.0	-1.0	-1.0	-2.3	-1.7	-1.2	-2.0	-1.5	-1.9	-0.1	-1.8	-1.6	-1.1	-2.5	-1.7	-0.8	-1.9	-2.0
Length of working week for main job	0.5	0.5	2.1	-0.2	1.1	1.4	0.2	0.3	1.4	0.1	0.8	0.9	0.1	0.2	0.8	-0.6	-0.1	-0.4	-1.0	-0.3	-0.0	-0.8
Hair/balding pattern: Pattern 4	0.5	1.1	6.0	0.6	2.4	0.6	1.5	0.4	1.6	0.5	2.1	1.0	-0.7	-0.2	0.6	0.5	0.8	0.7	-0.4	0.5	1.0	0.4
Gout (self-reported)	0.5	0.7	3.6	0.4	0.3	-0.6	1.0	-0.2	-0.3	0.9	0.6	-0.5	-0.6	-0.1	-1.9	1.0	1.5	-0.3	-0.3	0.6	0.6	1.4
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.9	-1.5	-0.6	-0.9	-1.7	-1.3	-0.8	-1.3	-1.2	-0.1	0.6	-0.8	0.4	-1.0	-1.3	-0.6	-0.9	-0.8	-1.2	-0.7
Leg fat percentage (right)	0.5	1.7	8.8	-0.6	-1.6	-2.5	-0.8	-0.3	-1.9	-0.3	-1.1	-0.4	2.4	-1.1	3.0	-0.2	-0.1	-0.8	-0.5	-0.5	-0.8	0.4
Arm fat-free mass (right)	0.5	2.4	5.1	-1.8	-1.9	-1.2	-1.0	-1.9	-1.5	-0.8	-2.0	-1.2	-1.3	-0.2	-1.5	-1.5	-1.2	-2.2	-1.6	-0.7	-2.0	-2.0
Qualifications: College or University degree	0.5	1.5	4.7	0.3	2.2	1.1	1.6	0.2	1.8	0.1	1.7	0.6	-1.1	-1.7	-0.7	1.3	1.9	0.4	0.0	0.5	1.5	1.3
Medication: Omeprazole	0.5	0.6	4.8	0.8	0.5	0.0	-0.8	-0.5	-0.6	-0.2	0.5	0.9	0.8	0.0	2.2	0.7	0.0	1.3	0.3	-0.2	0.6	0.6
Heart disease (mother)	0.5	0.6	2.4	0.5	0.1	0.2	0.6	1.4	0.4	0.2	0.2	0.0	-0.0	0.7	1.6	0.8	0.1	1.2	1.5	0.9	0.8	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.8	-0.9	0.4	0.6	-0.3	-0.9	0.3	-0.3	-0.1	0.2	-0.6	-1.1	-0.2	-1.3	-1.7	-0.0	-0.9	-0.7	-0.8	-1.3
Leg fat mass (right)	0.5	1.8	6.5	-0.9	-2.0	-2.5	-1.0	-0.8	-1.9	-0.4	-1.6	-0.7	2.0	-0.7	2.0	-0.6	-0.2	-1.5	-0.7	-0.4	-1.3	-0.3
Arm predicted mass (right)	0.5	2.6	5.9	-1.8	-1.9	-1.2	-1.0	-2.1	-1.5	-0.8	-2.0	-1.2	-1.5	-0.4	-1.5	-1.7	-1.2	-2.4	-1.7	-0.8	-2.0	-2.1
Comparative height size at age 10	0.5	2.7	16.1	-0.9	-1.6	-1.7	-2.5	-2.8	-4.0	-1.8	-1.5	-1.9	0.0	-0.5	-1.6	-0.3	-0.6	-1.0	-0.6	0.2	-1.2	-0.2
Whole body fat-free mass	0.5	2.9	7.0	-1.8	-2.3	-1.5	-1.2	-2.1	-1.8	-1.0	-2.2	-1.4	-0.9	-0.0	-1.5	-1.6	-1.1	-2.6	-1.6	-0.9	-2.2	-2.0
Qualifications: nursing, teaching	0.5	0.8	3.3	-1.0	0.4	1.2	1.8	0.6	1.1	-0.1	-0.1	-0.2	-1.8	-1.6	-1.0	-0.2	-0.1	0.1	-0.1	-0.5	-0.1	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.3	0.5	1.0	0.5	-0.9	-0.4	-0.6	0.1	1.1	0.8	1.8	-0.1	0.0	0.6	-0.1	1.0	-0.5	0.8	0.3	0.8
Mineral and other dietary supplements	0.5	0.6	4.7	0.2	-0.1	0.0	-2.2	-0.5	0.3	0.2	-0.1	0.2	0.6	-0.0	-0.2	-1.2	-1.5	0.1	-0.3	-0.5	-0.8	-1.3
Whole body water mass	0.5	2.8	6.5	-1.8	-2.2	-1.4	-1.2	-2.1	-1.8	-1.0	-2.2	-1.4	-1.0	-0.0	-1.5	-1.6	-1.1	-2.6	-1.5	-0.8	-2.1	-2.0
Leg predicted mass (right)	0.5	2.8	7.5	-1.9	-2.5	-1.9	-1.3	-1.7	-1.6	-0.8	-2.4	-1.4	0.3	0.2	-1.0	-1.7	-1.0	-2.7	-1.5	-0.9	-2.3	-1.9
Arm fat mass (left)	0.5	1.9	6.6	-1.0	-2.1	-2.6	-0.8	-0.4	-1.8	-0.3	-1.7	-0.9	2.5	-0.2	2.3	-0.6	-0.3	-1.5	-0.5	-0.2	-1.4	-0.3
Medication: Paracetamol	0.5	0.8	6.3	-0.6	-1.2	-1.6	-1.0	-0.5	-2.5	-0.4	-1.1	-1.1	0.8	0.1	-0.2	-0.2	-0.4	-0.2	-0.0	-0.4	-0.7	0.2
Basal metabolic rate	0.5	2.7	6.5	-1.8	-2.4	-1.7	-1.3	-2.0	-2.1	-1.1	-2.3	-1.4	-0.4	-0.1	-1.0	-1.5	-1.0	-2.6	-1.5	-0.8	-2.1	-1.8
Leg fat percentage (left)	0.5	1.7	8.1	-0.7	-1.6	-2.5	-0.9	-0.5	-1.8	0.1	-1.2	-0.2	2.3	-1.0	2.9	-0.3	-0.2	-0.8	-0.7	-0.7	-0.9	0.3
Ever depressed for a whole week	0.5	0.7	4.0	-0.3	-0.8	-0.8	1.5	0.7	0.5	-0.3	-0.4	-2.0	-0.4	0.4	-0.4	-0.7	-0.1	-1.1	0.6	0.5	-0.8	-0.7
Myopia	0.5	0.7	4.6	-0.9	-0.8	-0.0	0.1	0.3	0.6	-0.5	-0.8	-2.1	-0.7	-0.3	-0.1	-0.9	-0.5	-1.1	0.3	-0.1	-0.8	-1.5
Leg fat mass (left)	0.5	2.0	7.1	-1.1	-2.1	-2.7	-1.2	-1.2	-2.1	-0.3	-1.8	-0.8	1.9	-0.8	1.7	-0.8	-0.4	-1.7	-0.9	-0.7	-1.5	-0.5
Arm predicted mass (left)	0.5	2.7	5.1	-1.7	-2.1	-1.4	-0.8	-2.2	-2.1	-1.0	-2.1	-1.6	-1.4	-0.3	-1.5	-1.4	-1.2	-2.2	-1.6	-0.8	-2.0	-1.8
Schizophrenia (2018)	0.4	0.9	2.9	1.0	-0.6	1.1	-1.2	-0.2	-0.7	1.2	0.3	1.7	0.5	1.3	-0.4	1.0	0.8	1.2	1.3	0.6	0.3	1.0
Reaction Time	0.4	0.7	2.8	-0.1	-1.2	-1.0	-0.8	-1.0	-1.1	-0.6	-0.7	-1.2	1.7	-0.6	-0.2	-0.6	-0.6	-0.4	-0.1	-0.1	-1.0	-0.7
Bipolar Disorder (2011)	0.4	0.3	1.5	-0.7	-0.4	-0.6	-1.2	-1.1	-0.3	-0.4	-0.4	0.2	-1.1	-0.6	0.2	0.1	-0.2	-0.1	-0.5	-0.4	-0.1	0.3
Schizophrenia (2014)	0.4	0.9	3.2	1.0	-0.4	1.2	-1.3	-0.8	-0.7	0.8	0.5	1.8	-0.3	1.1	-0.2	1.0	0.9	1.0	0.9	0.3	0.4	1.1
BMI	0.4	2.3	6.5	-1.3	-2.5	-2.1	-0.4	-0.5	-2.0	-0.5	-2.1	-1.0	2.2	-0.4	1.1	-1.2	-0.5	-2.3	-1.1	-0.9	-2.1	-1.1
Systolic Blood Pressure	0.4	2.0	6.2	1.1	2.2	1.7	0.0	0.1	1.2	-0.2	1.8	0.7	-0.7	-0.3	-2.0	2.0	2.5	0.7	0.5	1.1	2.0	1.6
Respiratory disease	0.4	0.9	3.1	-0.5	-0.0	-1.4	-0.2	-0.6	0.5	1.3	-0.1	-0.5	0.5	-0.0	0.8	-1.4	-0.8	-1.2	-1.8	-1.4	-0.8	-0.8
Sensitivity / hurt feelings	0.4	0.8	1.8	-0.9	-0.9	-0.9	-0.9	-0.8	-0.0	-0.7	-1.2	-0.9	0.6	-0.9	0.1	-1.1	-1.3	-0.4	-0.9	-1.4	-1.0	-0.6
Medication: Co-codamol	0.4	0.4	1.8	-0.7	-0.4	-1.1	0.6	-0.5	-1.1	0.4	-0.4	-0.2	-0.9	-0.5	-0.4	0.4	0.2	-0.5	-1.3	-0.0	-0.6	0.5
Fed-up feelings	0.4	0.7	2.4	-0.4	-0.5	-1.0	-1.0	-1.1	-0.1	-0.1	-0.8	-0.1	0.8	0.5	1.6	-1.0	-1.1	0.1	-0.0	-1.2	-0.8	-0.7
Stomach or abdominal pain in last month	0.4	0.5	2.8	-0.3	-0.5	-0.8	-0.5	0.1	-1.2	-0.2	-0.5	-0.7	-0.4	-1.0	-1.7	-0.1	-0.3	0.2	-0.3	-0.9	-0.3	0.5
Supplements: Glucosamine	0.4	0.6	3.3	-0.6	-0.0	-0.3	1.8	0.5	-1.0	-0.8	-0.4	-1.0	-1.0	0.1	-0.3	1.1	0.6	-0.2	-0.2	0.8	0.5	0.6
Pain all over the body in last month	0.4	0.5	2.2	-0.2	1.0	0.0	-0.6	-0.8	-0.3	0.3	0.9	-0.4	1.0	-1.2	0.5	-0.6	-0.2	-0.6	-1.5	-0.3	-0.1	-0.1
Fluid intelligence score	0.4	0.9	4.4	0.5	2.1	0.8	0.5	0.3	1.4	0.9	1.7	0.5	-0.8	-0.5	-1.1	0.2	1.1	0.4	0.1	0.3	0.9	1.0
Hip circumference	0.4	1.9	6.7	-0.9	-2.0	-2.6	-0.1	-1.3	-1.7	-0.6	-1.5	-1.3	1.2	-0.7	1.6	-0.8	0.0	-2.3	-1.4	-0.4	-1.5	-0.8
Time employed in main current job	0.4	0.4	1.2	-0.8	0.9	-0.2	0.2	-0.4	0.4	0.3	0.0	0.3	-1.1	-1.0	-0.8	-0.6	-0.8	-0.2	-1.1	-0.6	-0.0	-0.8
Noisy workplace	0.4	0.5	3.1	0.9	-0.4	-0.6	-0.9	-0.5	-0.8	-0.3	0.0	0.7	1.7	0.4	1.4	0.6	0.7	0.1	0.4	0.2	0.3	0.5
Arm fat mass (right)	0.4	1.7	6.1	-0.9	-1.9	-2.4	-0.7	-0.5	-1.7	-0.3	-1.5	-0.8	2.5	-0.1	2.4	-0.6	-0.3	-1.4	-0.6	-0.2	-1.2	-0.3
Loud music exposure frequency	0.4	0.4	1.4	-0.2	-0.8	-1.0	-0.8	-0.5	-1.2	-1.2	-0.3	-1.0	-0.6	0.7	-0.3	-0.2	-0.5	-0.2	0.4	0.2	-0.7	-0.4
Blood clot in the leg (DVT)	0.4	0.5	2.3	1.3	-0.4	-0.4	0.0	0.1	-0.8	0.1	0.3	-0.2	1.5	0.5	0.6	0.6	0.5	0.7	1.4	1.2	-0.1	0.3
Medication: Paracetamol	0.4	0.7	6.3	-0.3	-1.0	-1.0	-0.7	-0.6	-2.5	-0.5	-0.8	-0.6	1.3	0.6	-0.2	-0.0	-0.2	-0.3	-0.1	-0.1	-0.5	0.2
Number of full brothers	0.4	0.5	2.8	0.6	0.2	-0.1	-0.8	0.4	-0.1	0.3	0.4	0.7	1.6	0.6	1.7	0.5	0.9	-0.3	-0.2	0.3	0.2	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.6	0.5	0.7	0.3	0.1	0.9	1.1	-0.2	0.6	0.5	1.2	0.7	0.9	0.6	0.6	0.5	0.9	1.1	0.5	0.4
Medication for pain relief, constipation, heartburn	0.4	0.7	2.9	0.9	0.5	1.3	1.2	0.8	1.7	0.3	0.7	-0.2	-1.1	0.8	0.0	0.8	0.9	0.4	0.9	0.9	0.7	0.4
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.7	-0.4	-1.3	-1.7	-0.4	-0.8	-0.6	0.5	-0.9	-0.2	0.6	0.7	0.2	-0.0	0.2	-0.9	-0.5	-0.2	-0.7	0.2
Supplements: Vitamin C	0.4	0.4	1.0	-0.9	-0.7	-0.2	1.0	-0.1	-0.8	-0.9	-1.0	-0.8	-0.8	-0.1	-0.3	-0.3	-0.4	-0.8	-0.3	-0.5	-0.4	-0.8
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.5	-0.6	0.1	0.1	-0.9	0.0	-0.6	0.2	-0.4	-0.6	-0.1	0.3	-1.6	-0.9	-0.8	-0.7	-1.0	-0.8	-0.7	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.8	-0.2	-0.1	0.3	-1.3	-0.3	0.6	-0.5	-0.5	0.2	0.8	-0.4	1.2	-1.0	-0.9	-0.0	0.2	-1.0	-0.4	-0.9
Commuting to job workplace: Walk	0.4	0.4	1.1	0.7	0.6	0.8	-1.0	0.2	0.7	0.3	0.8	1.0	0.7	0.6	-0.0	0.4	0.5	0.4	0.4	0.5	0.8	-0.0
Guilty feelings	0.4	0.6	3.8	0.0	-0.5	-1.3	-0.3	-0.2	-0.2	1.6	-0.0	-0.3	2.0	-0.8	0.3	-0.4	-0.1	0.2	-0.5	-0.9	-0.2	0.9
Medication: Lisinopril	0.4	0.5	1.3	-0.5	0.8	1.0	0.6	-0.3	0.4	-0.6	0.4	-0.8	-0.6	-1.1	-0.0	-0.8	0.2	-1.1	-1.0	-0.9	-0.1	-1.1
Illnesses of father: High blood pressure	0.4	0.5	2.4	0.3	0.3	0.4	0.6	1.5	0.3	0.5	0.1	0.2	0.4	0.9	-1.1	0.6	0.8	0.1	1.2	1.2	0.7	0.0
Alcohol drinker status: Never	0.4	0.4	3.8	0.4	0.3	-0.3	-0.1	-0.5	0.1	0.4	0.6	1.0	0.6	0.8	1.9	-0.1	-0.2	0.7	-0.2	-0.8	0.1	0.2
Supplements: Calcium	0.4	0.5	2.5	0.3	0.2	0.9	1.6	0.9	0.1	-0.3	-0.0	-0.3	-1.0	0.7	0.3	0.8	0.2	0.8	0.9	0.9	0.6	0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	2.5	1.4	-0.1	-0.1	0.4	0.3	-0.7	0.2	0.5	0.0	1.6	0.5	0.7	0.5	0.5	0.8	1.4	1.1	0.1	0.3
Bipolar Disorder or Schizophrenia	0.3	0.8	7.3	-0.3	-1.2	0.3	-2.7	-1.1	-0.4	0.2	-0.8	0.8	-0.5	0.1	-1.4	-0.2	-0.1	-0.1	0.0	-1.0	-0.5	0.0
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.1	1.3	1.8	0.2	0.2	0.2	0.8	0.2	1.7	0.2	-0.2	-0.5	-0.5	1.1	1.3	1.0	0.6	1.2	1.3	1.4
Schizophrenia vs Biploar Disorder	0.3	0.5	2.5	0.8	-0.8	-0.5	0.1	-0.3	-1.6	-0.1	-0.2	0.4	1.0	0.9	-0.1	0.1	-0.6	1.0	1.0	0.3	-0.2	0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.7	3.3	0.7	1.8	0.4	-0.5	0.6	1.4	0.5	1.5	0.4	0.6	-0.3	0.6	0.4	1.0	0.8	0.7	0.4	0.9	0.8
Body Mass Index (BMI) (2010)	0.3	0.4	2.1	0.4	-0.4	-0.7	-0.7	-0.7	-1.3	-0.0	0.1	0.1	1.5	0.6	0.0	0.5	0.8	-0.3	-0.3	0.3	0.1	0.8
Smoking Status	0.3	0.8	2.3	-0.2	1.1	0.7	-0.7	-0.1	0.4	-1.0	0.9	0.1	1.5	0.7	1.5	-1.3	-0.6	-1.0	-1.3	-0.1	-0.3	-1.3
Lung FEV1/FVC ratio	0.3	1.6	6.1	0.8	-0.9	0.7	-0.5	1.6	1.1	1.3	-0.0	1.7	2.5	2.0	1.4	0.7	0.8	0.5	2.3	1.2	0.3	0.4
Vitamin and mineral supplements	0.3	0.5	2.0	-0.3	0.2	-0.0	-1.4	-0.9	0.2	-0.3	0.1	-0.3	0.0	-1.4	-0.6	-0.8	-0.5	-0.6	-0.9	-0.8	-0.7	-0.6
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	-0.2	1.1	-0.2	0.5	0.5	0.5	0.4	0.6	-0.1	0.8	-0.9	0.4	0.8	0.5	0.6	-0.4	0.1	0.8	0.9
Waist circumference	0.3	1.1	7.6	-0.4	-1.2	-1.7	-1.3	0.1	-0.6	0.9	-0.8	0.3	2.8	0.7	1.8	0.1	0.3	-0.7	0.0	0.5	-0.6	0.0
Had other major operations	0.3	0.4	1.8	-0.1	0.3	0.5	-0.8	1.4	-0.2	-0.7	0.0	-0.3	0.0	1.1	0.6	0.4	-0.5	1.0	0.5	0.9	0.3	-0.1
Allergy	0.3	0.7	4.0	-0.5	-0.3	0.9	-0.2	-0.9	-0.4	-2.0	-0.6	0.4	-1.3	-0.6	-1.9	0.3	0.3	-0.6	-0.4	0.0	0.1	-0.2
Father’s age at death	0.3	0.4	2.6	-0.8	0.3	1.0	1.3	0.5	0.9	-0.5	-0.2	-0.3	-1.6	-0.6	0.4	-0.0	0.2	-0.0	0.6	-0.4	-0.1	-0.2
Hair/balding pattern: Pattern 3	0.3	0.5	1.3	0.9	0.3	1.2	-0.1	0.3	0.5	0.3	0.2	1.1	-0.8	0.3	0.6	0.8	0.4	1.0	1.1	0.5	0.9	0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.6	-0.8	0.8	1.4	0.6	1.0	1.9	0.7	0.4	0.2	-0.8	-0.2	-0.4	0.1	0.7	-0.2	0.7	0.6	0.2	-0.3
Medication: Cholesterol lowering	0.3	0.5	1.9	0.9	-0.8	-1.4	0.0	0.3	-0.1	0.9	0.1	0.3	1.0	1.2	-0.5	0.4	0.5	-0.0	0.7	1.0	-0.1	0.8
Lung cancer (father)	0.3	0.4	2.2	-0.2	-0.4	-0.1	1.5	0.6	0.4	0.3	-0.6	-0.4	-1.0	1.1	0.1	0.7	0.8	-0.3	0.5	0.5	0.5	0.2
Impedance of arm (left)	0.3	1.2	10.8	0.4	0.1	-1.0	-0.8	1.0	-0.8	-1.3	0.2	-0.3	3.3	-0.5	1.5	0.5	0.1	0.9	1.1	0.5	0.6	1.0
Peak expiratory flow (PEF)	0.3	0.8	4.8	-0.5	-0.1	1.3	0.9	0.5	-0.3	-1.4	-0.4	-0.5	-2.2	-0.0	-1.2	-0.9	-0.9	-0.5	0.2	-0.6	-0.3	-1.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.6	-0.6	-0.1	1.3	0.9	0.2	-0.0	-0.4	-0.7	-0.9	-1.1	-0.6	0.8	-0.8	-1.1	-0.0	-0.4	-0.9	-0.1	-1.0
Emphysema/chronic bronchitis	0.3	0.3	1.1	-0.4	0.3	-0.7	0.3	-0.3	0.7	0.9	0.1	0.3	-0.8	-0.5	0.7	-0.3	-0.1	-0.7	-1.0	-0.4	-0.1	-0.2
Neck or shoulder pain in last month	0.3	0.4	2.0	-0.3	-0.8	-0.3	-0.1	-0.5	-1.4	0.4	-0.5	-0.6	-0.8	-0.5	-1.1	0.4	0.2	-0.2	-0.3	0.3	-0.3	0.8
Medication: Blood pressure	0.3	0.5	3.6	-0.4	-0.0	-1.9	-1.4	-1.0	-0.1	-0.7	0.3	0.4	0.6	0.2	-0.6	-0.1	0.4	-0.9	-0.8	-0.2	-0.5	0.2
Mean time to correctly identify matches	0.3	0.5	4.1	0.7	-0.7	-0.9	-1.0	-0.5	-0.6	-0.4	-0.1	-0.7	2.0	-0.2	0.6	0.5	0.4	0.4	0.4	0.5	-0.0	0.5
Had major operations	0.3	0.4	1.4	0.9	0.2	0.6	-0.1	-0.7	-1.1	-0.3	0.5	0.7	0.2	0.7	0.9	0.4	-0.3	1.2	0.3	0.6	0.1	0.5
Medication: Aspirin	0.3	0.4	2.6	0.4	0.1	-0.4	0.2	-0.2	-0.2	1.2	0.5	1.3	1.6	-0.5	0.4	-0.0	0.4	-0.1	-0.3	-0.4	0.1	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	-0.7	-0.9	-1.3	0.1	-0.1	-0.5	-1.0	-0.8	-0.4	-0.2	-0.3	0.3	-0.3	-0.8	-0.2	-0.7	-0.2	-0.4	0.1
Average weekly red wine intake	0.3	0.5	1.2	0.8	0.9	0.7	0.3	-0.2	0.1	-0.7	0.9	1.0	-1.0	-0.2	-0.6	1.0	0.6	1.1	0.1	0.3	1.0	0.6
Friendships satisfaction	0.3	0.4	2.2	-0.1	-0.2	-1.4	-0.1	-0.7	-0.3	0.6	0.2	-0.5	0.3	-1.5	0.1	-0.3	0.3	-0.7	-0.7	-0.7	-0.3	-0.0
Osteoarthritis (self-reported)	0.3	0.3	1.4	-0.5	0.2	-0.5	1.2	0.6	-0.5	0.4	0.2	0.0	-0.1	-0.5	0.6	0.9	0.7	0.3	-0.2	0.2	0.5	1.2
Smoking status: Current	0.3	0.5	1.3	-0.2	-0.6	0.1	-0.8	-0.2	-1.1	-0.3	-0.2	-0.4	1.2	0.9	0.3	-0.9	-0.8	-0.7	-0.7	0.1	-1.0	-1.1
Average weekly champagne plus white wine intake	0.3	0.4	2.5	0.9	-0.1	-0.7	-0.7	-0.6	-1.0	0.2	0.0	0.3	0.5	-0.0	-0.2	0.8	0.8	0.6	0.1	-0.6	0.4	1.6
Wears glasses or contact lenses	0.3	0.4	1.0	-0.5	-0.4	-0.2	0.6	0.7	1.0	0.5	-0.5	-1.0	-0.5	-0.9	0.9	-0.7	-0.6	-0.3	-0.2	-0.5	-0.5	-0.5
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.7	-0.3	0.9	0.0	-0.3	-0.8	0.3	0.4	0.5	0.1	0.8	-0.9	0.6	-0.5	-0.5	-0.3	-1.3	-0.6	-0.1	0.0
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.0	-0.3	-0.6	-0.9	0.4	-0.8	-1.2	0.0	-0.1	-0.0	0.6	-0.2	0.4	0.5	1.1	-0.7	-0.5	-0.4	0.1	1.4
High cholesterol (Self-reported)	0.3	0.6	2.6	-0.7	-0.7	-1.6	-0.9	0.1	0.1	0.3	-0.7	-0.4	1.3	0.0	0.0	-0.5	-0.3	-1.3	-1.0	-0.6	-0.7	-0.5
Number of operations (self-reported)	0.3	0.5	1.8	-0.4	-0.6	0.2	-1.3	-0.9	-1.0	-1.2	-0.8	-0.2	0.3	0.1	0.1	-0.4	-1.1	0.5	-0.0	-0.6	-0.8	-0.3
Irritability	0.3	0.5	3.4	-0.3	-0.5	-0.4	-1.8	0.0	-0.5	0.1	-0.3	0.5	1.1	0.4	-0.2	-0.8	-0.3	-0.6	-0.7	-1.3	-0.6	-0.3
Basal cell carcinoma (self-reported)	0.3	0.3	1.7	-0.3	-1.3	-0.1	0.0	-0.4	0.0	0.7	-0.8	-0.2	0.3	-0.0	-0.3	0.1	0.7	-0.9	0.7	0.7	-0.4	-0.4
Age at First Birth	0.2	0.3	1.5	-0.1	-0.5	-0.4	-0.2	0.3	-0.7	-1.2	-0.4	-0.7	0.5	-0.1	-1.1	0.2	0.1	-0.3	-0.1	0.1	-0.1	0.7
Ulcerative Colitis	0.2	0.3	3.1	-0.0	-0.1	0.7	-0.3	0.5	0.0	-0.9	-0.3	-0.1	-0.3	0.0	0.2	-0.1	-0.2	0.8	1.8	0.3	0.1	-0.5
Blood Eosinophil Count	0.2	1.5	4.2	-0.4	-1.7	-1.6	-1.0	-2.0	-1.6	-0.5	-1.8	-1.2	-0.8	-0.7	0.3	-1.1	-1.3	-1.1	-0.6	-1.4	-1.3	-0.9
Cardiovascular Disease	0.2	0.7	2.7	-0.8	-0.4	-1.2	-1.6	-0.4	-0.5	0.5	-0.6	-0.1	-0.0	-0.1	-1.6	-0.6	-0.3	-1.2	-1.0	-0.6	-0.8	-0.7
Hypothyroidism (self reported)	0.2	0.5	1.6	-1.2	0.2	0.2	-1.2	-0.7	-0.1	-0.9	-0.7	0.5	0.0	-0.1	0.4	-0.9	-1.1	-0.3	-0.4	-0.1	-0.9	-1.0
Impedance of leg (right)	0.2	0.8	4.1	0.4	0.9	0.3	-0.5	-0.4	-1.2	-1.9	0.6	-0.3	-0.4	-2.0	0.1	0.4	-0.4	1.4	0.7	-0.1	0.8	0.5
Townsend deprivation index at recruitment	0.2	0.2	1.3	0.0	0.7	1.1	0.4	0.0	0.2	-0.7	0.6	0.5	-0.3	-0.1	0.7	0.1	-0.1	0.4	-0.3	-0.0	0.4	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.8	-0.1	-0.3	-0.6	-0.0	-0.3	0.3	0.2	-0.1	0.1	0.5	0.3	0.3	-0.9	-0.4	-0.5	-0.3	-0.6	-0.6	-0.8
Relative age voice broke	0.2	0.3	1.1	1.1	0.0	-0.1	-0.5	-0.3	-0.2	0.7	0.3	0.2	0.4	0.8	-0.2	0.5	0.7	0.1	0.8	0.9	0.2	0.5
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.5	0.1	0.7	-0.4	0.4	1.6	0.8	1.4	0.7	-0.1	0.3	0.5	1.0	-0.5	-0.6	0.9	0.8	-0.1	0.1	-0.1
Multivitamins +/- minerals	0.2	0.3	0.9	-0.6	-0.7	-0.5	0.9	-0.2	-0.2	-0.7	-0.9	-0.8	-0.4	0.4	-0.1	-0.3	-0.4	-0.7	-0.5	0.1	-0.3	-0.2
Medication: Levothyroxine sodium	0.2	0.4	1.7	-0.8	-0.1	-0.8	-0.6	-0.4	-0.0	-1.3	-0.7	0.6	0.2	-0.3	0.9	-0.5	-0.8	-0.1	-0.5	-0.8	-0.5	-0.2
Body mass index (BMI)	0.2	1.0	5.2	-0.6	-1.5	-1.8	0.1	0.0	-0.7	0.5	-1.0	-0.1	1.9	0.1	2.3	-0.2	0.1	-1.1	-0.5	-0.1	-0.9	-0.0
Impedance of leg (left)	0.2	0.7	3.9	0.1	1.0	0.4	-0.6	-0.8	-1.2	-1.6	0.5	-0.0	-0.4	-2.0	-0.1	0.3	-0.6	1.4	0.3	-0.5	0.7	0.5
Impedance of arm (right)	0.2	1.1	9.5	0.2	-0.2	-1.1	-1.2	-0.1	-1.7	-1.6	-0.2	-0.9	3.1	-1.1	0.7	-0.0	-0.3	0.4	0.3	-0.3	0.0	0.8
Asthma	0.2	0.5	1.8	-0.3	0.2	-0.9	-0.1	-0.1	0.7	0.4	0.0	-0.6	0.7	-0.2	1.0	-1.0	-0.8	-0.7	-1.3	-1.0	-0.5	-0.7
Headache pain in last month	0.2	0.3	1.2	0.3	-0.5	-1.1	-0.5	0.7	-0.4	0.1	-0.2	-0.7	1.1	0.2	0.7	0.1	0.0	-0.0	0.4	1.0	0.1	0.2
Worry too long after embarrassment	0.2	0.3	1.3	-0.9	-0.3	-1.1	0.4	0.6	0.6	0.6	-0.3	0.2	0.1	0.2	0.9	-0.6	-0.5	-0.2	0.2	0.2	-0.5	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.9	0.3	0.4	0.0	0.4	0.3	-0.7	-0.3	0.4	0.2	-0.9	-0.6	0.3	0.4	0.2	0.4	-0.3	-0.4	0.8	0.9
Loneliness, isolation	0.2	0.3	1.1	-0.3	-1.0	-0.5	-0.5	-0.3	-0.3	-0.3	-1.1	-0.7	0.1	0.1	0.1	-0.5	-1.0	0.3	0.3	-0.4	-0.5	-0.3
Medication for cholesterol	0.2	0.3	2.0	0.4	-0.4	-0.3	1.4	-0.2	-0.8	0.1	-0.1	-0.8	-0.5	-0.0	-0.7	0.2	0.3	-0.1	0.3	0.5	-0.2	0.1
Asthma (self-reported)	0.2	0.4	1.9	-0.1	0.2	-1.0	-0.1	-0.2	0.5	0.7	0.2	-0.4	0.9	-0.2	0.9	-0.8	-0.4	-0.6	-1.4	-0.9	-0.3	-0.3
Medication: Aspirin	0.2	0.3	1.0	-0.0	0.0	-0.4	0.1	-0.2	0.1	0.8	0.2	1.0	1.0	-0.7	0.1	-0.1	0.4	-0.2	-0.6	-0.7	0.0	0.6
Illnesses of father: None of the above (group 1)	0.2	0.3	1.4	0.2	-0.7	0.1	-0.1	0.1	-0.1	-0.7	-0.5	-0.9	-0.3	0.2	0.7	0.5	0.2	0.3	1.2	0.9	0.3	0.3
Medication: Blood pressure	0.2	0.4	1.6	0.5	0.5	-0.2	-1.3	-0.3	-0.1	1.1	0.5	0.8	0.8	-0.4	-0.1	0.3	0.7	-0.1	-0.9	-0.8	0.6	0.9
Diastolic blood pressure, automated reading	0.2	0.7	4.4	1.1	-0.1	1.0	0.3	1.0	0.1	-0.1	-0.1	0.9	-0.2	0.1	0.7	1.0	0.4	1.6	2.1	0.4	0.9	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.1	-0.4	-0.5	1.4	1.1	0.6	0.4	-1.0	-0.7	-1.4	-0.8	-0.5	0.6	-0.4	-0.7	0.2	0.9	0.1	-0.2	-1.0
Cholesterol lowering medication	0.2	0.3	1.3	-0.4	-0.2	-1.0	-1.2	0.4	0.1	0.7	-0.3	0.4	0.6	-0.1	0.3	0.2	0.1	-0.4	-0.5	-0.6	0.2	0.2
Pack years of smoking	0.2	0.3	1.3	-0.1	-0.2	-0.1	0.1	-0.0	-1.1	1.1	-0.1	0.1	-0.4	0.0	-0.6	0.7	0.8	-0.4	-0.5	-0.0	-0.1	0.5
Impedance of whole body	0.2	0.8	3.7	0.4	0.5	-0.5	-0.9	0.2	-1.3	-1.5	0.4	-0.2	1.9	-1.2	0.6	0.4	-0.2	1.2	0.9	0.2	0.6	0.9
Rheumatoid Arthritis	0.1	0.2	0.6	0.3	-0.8	0.5	0.4	0.3	-0.3	-0.0	-0.3	-0.3	-0.1	0.4	0.3	0.5	0.4	0.2	0.7	0.5	0.0	0.6
Allergy or Eczema	0.1	0.4	1.9	-0.4	0.3	-0.9	0.5	1.0	0.8	1.4	0.3	-0.3	-0.7	0.5	0.1	-0.7	-0.6	0.1	0.2	-0.0	-0.3	-0.5
Lung FVC	0.1	0.4	3.2	1.2	-0.5	0.9	-0.2	-0.2	-0.2	-0.1	0.0	0.7	-1.1	1.8	0.0	0.2	0.1	0.3	0.5	0.4	0.3	0.3
Relative age of first facial hair	0.1	0.1	0.5	0.2	0.1	-0.1	0.6	0.3	-0.2	0.3	-0.2	-0.6	-0.4	-0.3	-0.5	0.2	0.4	-0.5	0.1	0.7	-0.0	0.0
Pack years adult smoking proportion	0.1	0.2	1.8	-0.2	-0.2	0.1	0.3	0.1	-1.3	0.6	-0.3	-0.1	-0.7	0.2	-0.6	0.3	0.4	-0.5	-0.6	-0.1	-0.3	0.0
High blood pressure	0.1	0.4	1.5	-0.2	0.3	-1.2	-1.0	-0.1	-0.1	0.9	0.4	0.9	0.7	0.0	-0.7	0.2	0.6	-0.3	-0.6	-0.4	0.1	0.7
Pulse wave reflection index	0.1	0.1	0.5	0.2	-0.3	-0.0	-0.4	-0.1	-0.7	0.1	-0.2	-0.5	-0.5	0.6	0.1	0.2	-0.6	0.4	0.3	0.2	0.0	-0.2
Hypertension (Self-reported)	0.1	0.3	1.7	-0.4	0.1	-1.3	-1.0	-0.3	-0.3	0.2	0.1	0.3	0.6	-0.4	-0.7	-0.2	0.2	-0.5	-0.7	-0.7	-0.3	0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.1	0.0	-0.3	-1.0	-0.2	0.2	-0.7	0.3	-0.1	-0.2	1.1	0.3	-0.5	0.0	-0.1	0.1	-0.7	-0.2	-0.4	0.4
Commuting to job workplace: Public transport	0.1	0.1	0.5	0.1	0.3	0.6	0.1	0.5	-0.2	0.1	0.6	0.3	-0.3	-0.1	-0.5	0.2	0.2	0.6	0.2	-0.1	0.3	0.7
Hair Pigment	0.0	0.7	2.0	0.4	0.9	1.4	1.4	-0.1	-0.1	1.4	0.1	-0.1	-0.6	0.7	1.1	0.3	-0.5	1.3	1.2	1.3	-0.2	-0.4
Tanning	0.0	0.5	5.7	-0.3	0.3	0.1	-2.4	-1.3	0.2	-0.7	0.1	0.5	0.2	-0.0	0.5	-0.2	-0.5	0.3	-0.5	-0.6	-0.2	-0.2

Hub : Genes

RHPN2

Models

Trait associations