[Hub]/) : Traits : Heel T-Score : ← →

chr20:29,833,609-31,312,916

Best TWAS P=7.64e-13 · Best GWAS P=1.08e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	COX4I2	0.09	0.11	lasso	3	0.11	5.3e-09	6.5	7.2	7.6e-13	0.97	0.01	0.99	TRUE
2	GTEx	Brain Caudate basal ganglia	COX4I2	0.24	0.03	lasso	6	0.05	1.1e-02	6.2	5.4	7.9e-08	0.63	0.05	0.81	FALSE
3	GTEx	Brain Nucleus accumbens basal ganglia	COX4I2	0.13	0.14	lasso	5	0.05	2.2e-02	6.2	5.6	1.8e-08	0.83	0.06	0.57	FALSE
4	GTEx	Cells Transformed fibroblasts	HM13	0.07	0.05	lasso	4	0.06	3.9e-05	5.6	6.1	1.2e-09	0.81	0.04	0.95	FALSE
5	GTEx	Cells Transformed fibroblasts	HM13-AS1	0.04	0.01	lasso	3	0.01	1.0e-01	5.6	-5.8	6.6e-09	-0.85	0.07	0.69	FALSE
6	GTEx	Esophagus Muscularis	COX4I2	0.09	0.12	enet	10	0.09	4.1e-06	6.4	6.7	2.9e-11	0.99	0.02	0.98	FALSE
7	GTEx	Lung	COX4I2	0.05	0.01	enet	6	0.03	1.8e-03	6.5	7.0	2.4e-12	0.94	0.03	0.91	FALSE
8	GTEx	Muscle Skeletal	HM13	0.05	0.01	enet	15	0.05	2.1e-05	4.8	-6.2	4.2e-10	-0.70	0.04	0.91	FALSE
9	GTEx	Muscle Skeletal	COX4I2	0.10	0.08	lasso	4	0.09	3.5e-09	6.4	6.9	6.8e-12	0.93	0.02	0.98	FALSE
10	GTEx	Nerve Tibial	COX4I2	0.13	0.10	lasso	9	0.07	6.6e-06	6.4	6.2	4.1e-10	0.97	0.01	0.99	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	COX4I2	0.08	0.05	lasso	4	0.05	1.5e-03	6.2	6.0	1.9e-09	0.89	0.03	0.96	FALSE
12	GTEx	Skin Sun Exposed Lower leg	COX4I2	0.03	0.04	enet	6	0.04	3.6e-04	6.5	6.1	9.9e-10	0.98	0.03	0.95	FALSE
13	GTEx	Skin Sun Exposed Lower leg	HM13-AS1	0.07	0.07	enet	11	0.05	5.3e-05	6.0	-6.9	6.1e-12	-0.78	0.05	0.95	FALSE
14	GTEx	Thyroid	COX4I2	0.04	0.05	lasso	2	0.03	1.8e-03	6.5	6.5	6.5e-11	1.00	0.02	0.96	FALSE
15	GTEx	Vagina	COX4I2	0.17	0.12	lasso	2	0.16	1.5e-04	6.4	6.3	3.7e-10	0.84	0.03	0.88	FALSE
16	NTR	Blood	C20orf160	0.01	0.00	bslmm	305	0.00	8.0e-03	6.5	-6.7	1.6e-11	-0.74	0.03	0.61	FALSE
17	NTR	Blood	HM13	0.03	0.05	lasso	6	0.05	2.2e-15	5.7	5.7	1.1e-08	0.82	0.22	0.78	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	HM13	0.08	0.14	lasso	4	0.15	3.7e-19	5.6	-6.3	3.0e-10	-0.94	0.08	0.92	FALSE
19	YFS	Blood	HM13	0.08	0.10	lasso	6	0.10	3.6e-31	5.5	5.9	4.1e-09	0.85	0.15	0.85	FALSE
20	The Cancer Genome Atlas	Glioblastoma Multiforme	ID1	0.12	0.01	enet	4	0.05	1.3e-02	5.5	-6.4	1.6e-10	-0.73	0.01	0.35	FALSE
21	The Cancer Genome Atlas	Glioblastoma Multiforme	MYLK2	0.30	0.10	blup	43	0.16	1.3e-05	5.2	-6.2	7.3e-10	-0.63	0.01	0.84	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	COX4I2	0.06	0.03	lasso	3	0.03	1.5e-04	3.8	5.4	7.4e-08	0.95	0.01	0.97	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYLK2	0.06	0.02	blup	43	0.04	8.0e-06	5.9	-6.0	2.5e-09	-0.67	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	COX4I2	0.04	0.06	enet	6	0.05	9.8e-07	6.2	6.3	2.2e-10	0.87	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	COX4I2	0.04	0.03	blup	25	0.04	2.5e-05	3.7	5.4	8.1e-08	0.89	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	COX4I2	0.07	0.07	lasso	5	0.07	2.0e-07	6.5	6.2	7.3e-10	0.98	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Stomach Adenocarcinoma	COX4I2	0.09	0.03	blup	25	0.03	3.8e-03	6.4	6.3	2.3e-10	0.83	0.01	0.71	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	COX4I2	0.02	0.03	lasso	2	0.03	1.0e-03	6.5	6.5	1.1e-10	1.00	0.00	0.89	FALSE