TWAS hub - NCOA1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1030	0.0370	1.6e-05	0.074	0.049	0.059	0.053	0.068	2.5e-09	1.2e-06	1.0e-07	4.6e-07	9.9e-09
2	GTEx	Adipose Subcutaneous	0.0910	0.0440	7.5e-03	0.053	NA	0.028	NA	0.031	3.4e-05	NA	2.3e-03	NA	1.4e-03
3	GTEx	Adipose Visceral Omentum	0.1100	0.0470	5.5e-03	0.024	NA	0.023	NA	0.010	2.0e-02	NA	2.1e-02	NA	9.2e-02
4	GTEx	Artery Aorta	0.1520	0.0630	2.9e-03	0.004	NA	0.006	NA	-0.002	1.9e-01	NA	1.3e-01	NA	4.2e-01
5	GTEx	Artery Tibial	0.1044	0.0368	2.1e-04	0.064	NA	0.036	NA	0.052	1.0e-05	NA	7.5e-04	NA	6.0e-05
6	GTEx	Breast Mammary Tissue (Male)	0.1338	0.0838	5.1e-02	-0.013	NA	-0.013	NA	0.037	8.9e-01	NA	8.8e-01	NA	4.8e-02
7	GTEx	Breast Mammary Tissue (Female)	0.0191	0.0590	4.0e-01	-0.001	NA	-0.001	NA	-0.007	3.5e-01	NA	3.6e-01	NA	6.2e-01
8	GTEx	Esophagus Mucosa	0.2250	0.0620	1.3e-06	0.138	NA	0.157	NA	0.164	1.7e-09	NA	1.1e-10	NA	3.9e-11
9	GTEx	Esophagus Muscularis	0.1110	0.0480	4.8e-03	0.010	NA	0.012	NA	0.001	7.1e-02	NA	5.7e-02	NA	2.5e-01
10	GTEx	Lung	0.1184	0.0486	1.8e-03	0.036	NA	0.036	NA	0.061	8.7e-04	NA	8.2e-04	NA	2.0e-05
11	GTEx	Nerve Tibial	0.1276	0.0477	4.2e-04	0.021	NA	0.072	NA	0.066	1.2e-02	NA	8.9e-06	NA	1.9e-05
12	METSIM	Adipose	0.0686	0.0251	1.8e-05	0.050	0.041	0.045	0.044	0.049	5.4e-08	7.9e-07	2.6e-07	2.9e-07	6.1e-08
13	ROSMAP	Brain Pre-frontal Cortex	0.1019	0.0309	7.0e-07	0.070	0.047	0.062	0.056	0.075	2.3e-09	9.3e-07	2.1e-08	8.4e-08	6.6e-10
14	YFS	Blood	0.0598	0.0185	2.0e-06	0.012	0.025	0.034	0.028	0.033	6.8e-05	1.1e-08	2.1e-11	1.1e-09	4.3e-11
15	TCGA	Colon Adenocarcinoma	0.0590	0.0350	8.4e-03	0.039	0.024	0.030	NA	0.018	2.6e-03	1.5e-02	7.6e-03	NA	3.1e-02
16	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0800	0.0430	8.9e-04	0.065	0.052	0.046	NA	0.044	1.3e-04	5.8e-04	1.2e-03	NA	1.5e-03
17	TCGA	Lung Adenocarcinoma	0.0227	0.0128	5.6e-03	0.013	0.012	0.004	NA	0.010	1.1e-02	1.2e-02	1.0e-01	NA	2.4e-02
18	TCGA	Ovarian Serous Cystadenocarcinoma	0.0440	0.0300	7.8e-03	0.025	0.022	0.015	NA	0.012	7.6e-03	1.2e-02	3.3e-02	NA	5.1e-02
19	TCGA	Prostate Adenocarcinoma	0.0885	0.0450	7.3e-05	0.036	0.025	0.027	NA	0.024	1.2e-04	1.1e-03	6.5e-04	NA	1.3e-03
20	TCGA	Thyroid Carcinoma	0.1070	0.0480	2.4e-04	0.014	0.039	0.059	NA	0.039	1.5e-02	1.0e-04	1.9e-06	NA	1.0e-04
21	TCGA	Uterine Corpus Endometrial Carcinoma	0.2060	0.0850	2.9e-04	-0.009	0.079	0.079	NA	0.018	6.7e-01	3.1e-03	3.2e-03	NA	9.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21
Comparative body size at age 10	7.8	21.6	112.4	-0.0	1.0	3.2	5.8	-0.7	5.2	0.9	-3.3	10.6	8.2	1.1	1.8	1.7	4.4	-0.4	6.0	-8.5	-1.8	-0.7	5.2	-4.9
Medication: Ibuprofen (e.g. Nurofen)	6.0	7.6	13.9	-2.6	-3.3	-3.2	-3.3	-2.9	-3.0	-2.2	-2.6	-2.0	-3.0	-3.5	-3.1	-3.2	-0.9	-2.9	-3.7	-1.9	-3.0	-1.8	-1.5	-2.1
Medication: Ibuprofen	4.8	5.7	10.0	-2.4	-2.9	-2.9	-3.1	-2.6	-2.7	-1.5	-2.6	-1.4	-2.6	-3.1	-2.6	-2.8	-0.5	-2.5	-3.2	-1.5	-2.6	-1.5	-1.4	-1.7
Medication for pain relief, constipation, heartburn	4.6	7.9	14.2	3.5	3.7	3.8	3.7	2.1	3.0	2.4	2.1	1.8	2.5	3.6	3.3	3.5	0.9	3.0	3.7	1.0	2.5	1.6	1.9	1.9
Time employed in main current job	4.2	4.8	16.0	3.0	3.0	0.1	-0.5	3.1	0.2	1.2	0.9	-0.5	0.1	2.0	3.0	2.5	-0.5	2.1	2.3	4.0	3.4	2.9	0.5	2.2
Hand grip strength (right)	4.1	11.1	52.6	-1.8	-2.5	-1.8	-4.0	-1.5	-4.0	-3.8	-3.5	-5.2	-7.2	-4.2	-3.0	-3.5	-1.7	-0.2	-5.5	0.8	-1.5	-1.0	-1.7	1.1
Standing height	4.0	39.3	228.0	1.0	-0.1	-7.2	-12.4	1.6	-7.5	-4.0	1.5	-15.1	-11.1	-3.6	-0.1	-1.6	-2.0	2.0	-7.4	8.2	2.9	4.1	-0.5	4.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.0	4.8	11.5	2.3	2.4	1.4	0.8	3.1	0.0	2.6	1.4	0.2	1.3	2.0	2.9	2.2	1.5	2.1	2.4	3.4	3.3	3.1	1.1	1.7
Neuroticism (2016)	3.9	5.6	14.1	3.2	3.1	0.7	1.8	2.6	1.8	0.8	0.5	-0.0	1.7	3.8	2.5	3.2	2.2	2.7	1.5	2.9	3.1	1.9	2.2	3.1
Forced vital capacity (FVC)	3.8	14.8	77.4	-1.5	-2.3	-5.5	-7.3	-0.9	-3.9	-3.1	0.4	-8.8	-6.6	-3.5	-2.7	-3.0	-0.8	-0.2	-5.8	2.6	-0.6	-0.2	-1.0	0.7
Height	3.7	71.6	458.0	2.5	0.6	-10.5	-16.7	2.8	-8.3	-3.6	3.7	-21.4	-14.7	-4.1	0.8	-0.5	-0.6	3.3	-9.2	11.1	4.5	6.3	-0.5	5.7
Hand grip strength (left)	3.7	9.9	48.7	-1.5	-2.4	-2.3	-4.4	-1.4	-3.3	-3.6	-2.8	-5.0	-7.0	-4.0	-2.5	-3.2	-1.3	-0.4	-5.0	1.6	-1.1	-0.3	-1.8	0.7
Medication for hormone replacement therapy	3.6	4.0	8.8	-3.0	-2.8	-1.4	-1.2	-2.4	-1.5	-1.2	0.7	-1.5	-0.5	-1.4	-2.7	-2.6	-1.7	-2.7	-2.4	-1.2	-2.3	-2.3	-2.4	-1.1
Knee pain experienced in last month	3.6	5.6	11.8	-2.9	-3.0	-1.4	-2.4	-2.4	-1.9	-2.6	-1.3	-1.6	-2.2	-3.2	-2.8	-3.4	-1.9	-1.9	-2.9	-2.3	-2.6	-1.6	-0.8	-2.3
Sitting height	3.4	24.5	114.5	2.9	2.1	1.1	-2.2	3.2	-7.7	-2.0	4.7	-10.7	-9.5	-1.5	1.9	0.4	-2.4	4.6	-3.4	8.6	4.4	4.3	-0.9	6.2
Deep venous thrombosis (DVT) (self-reported)	3.4	4.4	8.6	2.6	2.8	2.3	1.5	2.5	0.5	1.3	1.6	1.2	0.9	2.2	2.4	2.7	1.2	2.9	2.1	1.8	2.6	1.8	2.0	2.8
Pulse rate, automated reading	3.3	10.8	24.8	-5.0	-4.1	-2.6	-1.3	-3.8	0.5	-3.2	1.3	-4.1	-1.2	-2.8	-4.4	-4.4	-2.0	-3.8	-4.3	-2.5	-3.9	-3.8	-2.5	-2.8
Comparative height size at age 10	3.3	17.9	106.1	1.1	0.2	-6.7	-9.1	1.2	-3.6	-1.0	0.3	-10.3	-6.0	-2.0	0.4	-0.6	0.7	1.1	-5.3	5.2	2.3	4.0	1.9	1.5
Trunk predicted mass	3.2	18.5	66.4	-2.5	-3.0	-4.6	-7.2	-1.8	-6.1	-5.0	-0.6	-8.2	-7.9	-5.5	-2.9	-4.3	-2.6	-0.6	-6.2	0.6	-1.7	-0.2	-1.0	-0.3
Blood clot in the leg (DVT)	3.2	4.1	7.8	2.4	2.6	2.5	1.8	2.1	0.5	1.1	1.7	1.4	1.1	2.3	2.3	2.6	1.4	2.7	2.2	1.4	2.3	1.5	1.9	2.8
Trunk fat-free mass	3.1	18.1	65.9	-2.4	-3.0	-4.5	-7.2	-1.8	-5.9	-4.9	-0.6	-8.1	-7.8	-5.4	-2.9	-4.2	-2.6	-0.6	-6.1	0.6	-1.6	-0.1	-1.0	-0.3
Forced vital capacity (FVC), Best measure	3.0	11.0	57.0	-0.5	-1.2	-4.7	-6.9	-0.2	-3.4	-2.4	-0.4	-7.5	-6.2	-2.9	-1.5	-2.1	-0.8	0.7	-4.6	2.6	0.0	0.7	-0.3	1.1
Illnesses of father: High blood pressure	3.0	3.7	22.0	-0.5	-1.2	-4.7	-4.7	-1.1	-1.7	0.2	-0.1	-3.0	-1.6	-1.4	-0.7	-1.0	1.6	-1.0	-2.3	-0.5	-0.9	0.5	0.8	-1.3
Forced expiratory volume in 1-second (FEV1)	2.9	9.8	53.0	-2.1	-2.4	-4.9	-5.6	-1.6	-2.1	-2.8	0.7	-7.3	-4.1	-2.5	-2.8	-2.9	-1.1	-1.0	-4.7	1.1	-1.3	-1.4	-1.5	-0.1
Number of treatments/medications taken	2.8	5.0	14.8	-3.1	-2.9	-3.9	-3.5	-2.3	-1.0	-1.3	0.5	-2.2	-0.7	-2.0	-2.3	-2.3	-0.8	-3.2	-2.7	-1.1	-2.2	-1.5	-1.8	-1.4
Mouth/teeth dental problems: Dentures	2.8	4.8	10.3	2.2	2.4	1.1	1.2	1.9	2.2	2.0	2.0	1.7	3.2	3.1	2.7	2.5	1.7	1.4	2.4	1.7	2.6	2.2	2.5	1.6
Arm fat-free mass (left)	2.8	14.2	40.3	-2.7	-3.2	-3.9	-5.8	-2.3	-5.2	-4.2	-1.2	-6.4	-6.3	-5.2	-3.1	-4.3	-2.6	-1.1	-5.3	-0.8	-2.3	-0.8	-0.6	-1.4
Arm predicted mass (left)	2.8	14.4	43.0	-2.6	-3.1	-4.2	-6.3	-2.2	-5.2	-4.3	-1.0	-6.6	-6.4	-5.0	-2.9	-4.2	-2.3	-1.1	-5.4	-0.6	-2.1	-0.5	-0.3	-1.1
Medication: Atenolol	2.7	3.4	14.8	-1.6	-2.1	-3.9	-2.7	-1.5	-0.1	-1.0	-0.9	-2.4	-1.3	-1.9	-1.8	-1.9	1.0	-1.9	-2.7	-1.3	-1.5	-0.6	-0.1	-2.0
Pain type(s) experienced in last month: Hip pain	2.7	3.4	9.2	-2.5	-2.6	-3.0	-2.2	-1.9	-0.2	0.3	-1.2	0.3	0.4	-1.6	-1.8	-2.2	0.6	-2.5	-1.7	-1.9	-2.0	-1.1	-1.6	-2.8
Major Depression (MDD)	2.5	3.0	5.7	2.1	2.2	1.6	1.1	2.1	-0.1	0.6	-1.4	2.1	0.9	1.0	2.4	2.0	1.1	1.9	2.3	1.6	2.3	2.4	1.5	1.2
HbA1C	2.5	2.7	6.8	-2.1	-2.2	-0.6	-1.3	-1.0	-0.1	-2.4	0.6	1.3	0.2	-1.0	-2.5	-1.7	0.3	-1.7	-1.8	-2.6	-2.3	-2.5	-1.0	-1.3
Medication: Ramipril	2.5	3.1	14.4	-1.6	-1.5	-3.8	-2.6	-1.8	-0.6	-0.2	-1.3	-1.8	-0.7	-1.5	-1.5	-1.7	0.7	-1.9	-2.7	-1.8	-1.9	-0.7	0.6	-2.1
Hypertension (Self-reported)	2.5	6.8	47.2	-0.0	-0.8	-6.9	-5.5	-0.5	-0.2	-0.7	-0.8	-5.3	-2.5	-1.8	-0.6	-0.6	0.7	-0.6	-3.5	0.4	-0.2	1.6	2.0	-2.3
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.6	7.2	-2.2	-1.9	-0.3	-0.9	-2.0	-0.5	0.2	0.2	-1.4	-0.8	-1.4	-2.7	-2.4	-1.4	-1.6	-2.0	-1.6	-2.1	-2.5	-1.5	-0.7
Arm fat-free mass (right)	2.4	12.3	41.3	-2.0	-2.7	-3.5	-5.2	-1.8	-4.7	-4.0	-1.2	-6.4	-6.4	-4.7	-2.8	-3.6	-2.8	-0.6	-5.0	-0.1	-1.8	-0.6	-1.0	-0.9
Arm predicted mass (right)	2.4	12.2	42.6	-2.0	-2.6	-3.4	-5.4	-1.7	-4.9	-3.9	-1.2	-6.2	-6.5	-4.8	-2.6	-3.6	-2.7	-0.5	-5.0	-0.1	-1.7	-0.4	-0.9	-0.9
Whole body water mass	2.4	13.8	48.7	-2.2	-2.7	-3.8	-6.1	-1.8	-5.4	-4.3	-0.5	-7.0	-6.7	-4.9	-2.5	-3.9	-2.2	-0.6	-5.1	0.0	-1.7	-0.2	-0.6	-0.7
Medication: Blood pressure	2.4	4.5	29.7	-1.2	-1.7	-5.5	-4.2	-0.9	0.1	-1.0	0.5	-4.1	-1.1	-1.4	-1.4	-1.2	-0.5	-1.2	-3.1	-0.4	-0.8	0.0	0.3	-2.3
Diastolic blood pressure, automated reading	2.4	7.5	25.3	-3.0	-2.8	-5.0	-3.8	-2.9	-0.5	-1.4	-0.5	-4.7	-1.9	-2.5	-3.0	-2.7	0.2	-2.8	-3.8	-1.6	-2.7	-1.9	-0.7	-2.3
High blood pressure	2.3	6.3	42.2	0.1	-0.7	-6.5	-5.4	-0.1	-0.2	-0.2	-0.9	-5.3	-2.4	-1.7	-0.5	-0.4	1.0	-0.2	-3.1	0.6	0.1	1.7	2.3	-2.1
Stomach or abdominal pain in last month	2.3	2.9	7.3	-2.7	-2.5	0.4	-0.8	-1.4	-2.3	-1.2	0.2	-0.6	-1.3	-2.3	-2.4	-2.6	-1.6	-0.9	-1.6	-1.7	-1.8	-1.8	-1.6	-0.9
Whole body fat-free mass	2.3	13.3	46.6	-2.1	-2.6	-3.6	-6.1	-1.6	-5.5	-4.2	-0.5	-6.8	-6.7	-4.9	-2.4	-3.8	-2.2	-0.4	-5.0	0.1	-1.5	-0.1	-0.6	-0.6
Hearing difficulty/problems with background noise	2.2	3.6	10.1	-3.2	-2.6	-1.7	-1.4	-2.2	-1.7	-1.5	-2.0	-0.4	0.8	-1.2	-2.2	-2.2	0.1	-2.8	-1.6	-2.1	-2.2	-2.1	-1.2	-1.4
Mouth/teeth dental problems: Loose teeth	2.2	2.7	7.6	-1.8	-1.8	0.9	0.9	-2.2	0.5	-2.5	-0.5	0.2	-0.2	-1.1	-2.5	-1.6	-0.8	-2.1	-1.5	-2.3	-2.4	-2.8	-1.0	-0.5
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	7.7	2.3	2.3	0.4	-0.5	1.8	-0.6	1.8	0.6	-1.2	-1.2	0.4	2.5	1.7	0.6	2.3	1.3	1.6	2.0	2.8	2.1	1.2
Lung FVC	2.1	10.7	21.6	-3.4	-3.9	-4.3	-4.7	-3.0	-2.3	-1.9	0.4	-3.8	-3.8	-4.0	-4.2	-4.2	-1.4	-2.2	-4.3	-2.4	-3.5	-2.8	-1.9	-2.3
Hearing aid user	2.1	2.3	7.0	-2.2	-2.2	-1.1	-0.3	-1.8	0.1	-0.2	-1.1	0.5	0.2	-2.0	-1.7	-1.6	-0.2	-1.9	-0.8	-2.6	-2.2	-1.4	-0.8	-2.2
Ulcerative Colitis	2.0	2.9	13.6	1.4	1.6	0.8	1.9	0.7	2.1	2.4	0.5	1.8	3.7	2.8	1.9	1.7	1.1	-0.1	2.8	0.4	1.0	0.4	0.1	0.0
Hearing difficulty/problems: Yes	2.0	3.1	7.9	-2.4	-2.2	-0.8	-0.2	-2.1	-0.2	-1.8	-2.1	0.2	0.5	-0.9	-2.4	-1.4	-0.8	-2.4	-1.4	-2.5	-2.5	-2.8	-1.4	-0.9
Suffer from ‘nerves’	2.0	3.1	8.0	2.8	2.5	1.3	0.4	1.7	0.6	0.3	-0.9	-1.3	-0.2	1.8	2.5	2.2	1.1	1.9	0.5	2.0	2.3	2.7	2.0	1.9
Fasting Glucose	1.9	2.3	6.5	1.0	1.6	2.1	2.5	1.3	0.8	0.3	0.3	1.1	2.3	2.5	1.5	1.7	0.2	0.6	1.3	2.0	1.4	0.2	-0.2	2.2
Systolic Blood Pressure	1.9	9.4	58.8	1.0	0.6	-7.2	-6.2	1.1	-1.1	1.0	0.1	-7.7	-2.5	0.3	0.6	0.7	1.7	-0.1	-3.2	3.8	1.7	2.2	0.7	1.0
Supplements: Glucosamine	1.9	2.5	8.6	-1.0	-1.7	-1.3	-2.2	-1.0	-2.2	-0.4	-0.4	-2.5	-2.9	-2.6	-1.2	-1.9	-0.3	-1.1	-1.6	-0.7	-1.3	0.1	-0.9	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.2	35.3	-1.0	-1.2	-4.2	-5.1	-0.7	-1.6	-2.2	-0.1	-5.9	-3.9	-2.0	-1.6	-1.9	-0.5	0.0	-3.5	1.3	-0.5	-0.4	-0.4	0.3
Alcohol intake frequency.	1.9	4.3	16.5	2.1	2.2	1.1	0.5	2.4	-0.0	1.8	-2.0	4.1	1.1	1.5	2.6	1.1	0.6	2.3	2.4	1.8	2.6	2.8	2.9	1.2
Basal metabolic rate	1.9	10.7	32.7	-2.0	-2.4	-3.5	-5.7	-1.6	-4.8	-3.9	-0.8	-5.7	-5.7	-4.6	-2.0	-3.5	-1.8	-0.5	-4.2	-0.6	-1.6	0.1	0.1	-1.1
Irritable Bowel Disease (IBD)	1.8	4.2	20.4	0.9	1.1	0.2	-0.1	1.0	2.2	3.4	0.9	3.6	4.5	2.2	1.6	1.9	1.7	-0.4	3.9	-1.5	0.5	0.3	1.1	-0.9
BMI	1.8	10.4	52.9	-2.5	-1.9	1.9	3.5	-2.5	1.4	-0.3	-1.4	6.7	4.2	-1.5	-1.2	-1.6	0.8	-2.0	3.0	-7.3	-3.4	-2.4	2.2	-4.8
Chronic bronchitis/emphysema (father)	1.8	2.1	5.0	1.7	1.7	1.6	1.5	2.1	0.3	0.4	-0.1	-0.2	0.4	1.4	1.6	1.2	-1.1	2.2	1.8	1.8	2.1	1.8	1.1	1.2
Ever unenthusiastic/disinterested for a whole week	1.8	2.1	6.2	1.5	1.3	1.3	0.7	2.2	2.5	1.1	-1.1	1.5	0.9	1.4	0.9	0.8	0.5	2.0	1.6	1.3	1.8	1.4	2.2	0.4
Exposure to tobacco smoke at home	1.8	2.0	6.1	1.9	1.7	-0.6	0.1	1.7	-0.3	0.5	-1.0	0.1	-0.4	1.2	1.8	1.2	-0.0	2.0	1.1	2.1	2.1	2.0	2.5	1.3
Medication: Blood pressure	1.8	3.2	12.1	0.4	-0.3	-3.5	-3.3	-0.2	-1.3	-1.3	-1.5	-2.9	-3.4	-1.9	-0.3	-0.5	0.7	-0.1	-2.9	0.7	-0.0	1.5	1.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	17.6	1.1	1.0	-1.9	-4.1	1.1	-2.6	-0.4	-1.6	-4.2	-2.4	-0.2	0.9	0.5	0.5	1.7	-1.1	2.4	1.6	1.9	1.2	2.1
Commuting to job workplace: Walk	1.8	2.0	4.2	1.2	1.6	1.4	0.9	2.0	1.0	1.7	-0.2	-0.1	1.1	1.5	1.6	1.4	0.7	1.9	2.0	1.5	1.9	1.4	1.1	1.2
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	10.1	-1.5	-1.5	-2.3	-1.6	-1.7	-1.0	-1.8	-0.8	-3.2	-1.7	-2.2	-1.4	-2.0	-1.8	-1.8	-1.9	-0.8	-1.5	-0.6	-1.1	-1.5
Number of operations (self-reported)	1.8	2.7	9.2	-1.1	-1.7	-2.2	-2.8	-0.9	-2.1	0.2	1.5	-2.9	-3.0	-1.8	-1.3	-1.7	-0.5	-0.6	-2.1	0.5	-0.7	0.1	-0.4	-0.3
Ever depressed for a whole week	1.8	2.3	5.0	1.8	1.6	2.1	2.1	2.2	0.7	0.6	-1.5	0.7	0.1	1.1	1.3	1.2	0.1	2.2	1.8	1.8	2.0	1.5	0.9	1.0
Cardiovascular Disease	1.7	5.5	42.5	-1.1	-1.4	-6.5	-5.1	-0.4	-0.6	-0.3	-1.2	-4.1	-1.7	-2.0	-0.7	-1.2	-0.5	-0.9	-2.6	0.5	-0.2	1.3	1.0	-2.2
Age when periods started (menarche)	1.7	4.1	13.8	-1.6	-1.7	-1.1	-0.6	-1.1	-1.6	-3.7	-0.5	-1.2	-3.2	-1.6	-2.2	-2.5	-3.4	-1.1	-2.9	0.6	-1.2	-1.8	-3.1	0.7
Body mass index (BMI)	1.7	7.2	38.8	-2.4	-2.0	0.6	1.7	-2.4	0.8	-1.0	-2.1	4.9	2.5	-2.2	-1.3	-2.1	0.2	-2.0	1.4	-6.2	-3.2	-1.7	1.8	-4.8
Medication: Bendroflumethiazide	1.7	2.5	11.6	-0.4	-1.0	-3.4	-2.9	-0.3	0.1	-1.1	-1.9	-2.5	-1.9	-2.1	-0.8	-0.8	-0.4	-0.6	-2.2	-0.2	-0.4	0.9	1.1	-1.9
Medication: Paracetamol	1.7	2.6	8.0	-2.3	-2.2	-2.8	-2.6	-1.5	-0.2	-1.1	-0.6	-0.7	0.4	-1.2	-2.0	-2.0	-0.6	-2.2	-1.6	-1.0	-1.7	-1.4	-0.5	-1.3
Vascular/heart problems diagnosed by doctor	1.7	4.6	29.5	0.1	0.7	5.4	4.7	-0.1	0.7	0.0	0.9	4.1	2.3	1.8	0.4	0.7	-0.7	-0.2	2.7	-0.3	-0.0	-1.6	-2.0	1.9
Worry (Nagel 2018)	1.6	3.3	9.9	2.8	2.4	2.2	1.4	1.3	0.4	-0.6	-0.4	-1.8	-0.4	2.0	2.1	2.7	1.1	1.5	0.4	2.5	2.1	1.8	0.7	3.1
Ovarian Cancer	1.6	2.2	5.9	-1.7	-1.4	-1.2	-0.8	-1.6	0.2	-1.6	-1.0	-2.1	-1.8	-1.9	-1.4	-1.8	-1.1	-1.8	-2.4	-0.7	-1.4	-0.9	-1.2	-0.8
Arm fat percentage (right)	1.6	6.2	29.7	-1.5	-0.9	0.4	1.3	-1.6	2.0	-0.3	-1.5	5.2	4.0	-0.7	0.2	-0.9	1.4	-1.8	2.6	-5.5	-2.0	-0.4	3.0	-4.1
Medication: Paracetamol	1.6	2.7	6.4	-2.3	-2.1	-2.4	-2.5	-1.8	-0.5	-1.5	-0.3	-1.2	-0.1	-1.4	-2.1	-2.3	-0.8	-2.1	-2.0	-1.1	-1.8	-1.5	-0.3	-0.8
Leg fat percentage (right)	1.6	6.0	32.9	-1.4	-1.1	0.2	1.3	-1.3	1.7	-0.8	-2.8	5.7	3.6	-0.8	-0.4	-0.6	0.4	-1.5	2.3	-5.0	-2.0	-0.8	2.2	-4.2
Medication for cholesterol	1.6	2.4	12.1	1.5	1.7	3.5	2.7	1.1	0.3	1.4	-0.3	2.3	0.7	1.1	1.4	1.0	0.6	1.3	2.5	0.9	1.0	0.3	0.1	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	7.0	-2.4	-2.2	-2.6	-1.8	-1.6	0.4	-0.6	0.2	-2.6	-1.5	-2.0	-2.4	-2.2	-1.0	-1.2	-2.5	-1.1	-2.0	-2.1	-1.4	-1.8
Tinnitus: Yes, now most or all of the time	1.6	1.9	4.9	-1.6	-2.2	-1.1	-1.1	-0.7	0.6	-0.9	0.2	-0.4	-1.5	-1.8	-2.0	-1.4	0.0	-1.3	-1.8	-0.8	-1.4	-1.4	-2.2	-1.6
Medication: Lisinopril	1.6	2.1	9.7	0.4	0.0	-3.1	-3.1	0.1	0.4	0.0	-0.2	-2.0	-2.4	-0.8	0.1	-0.0	-1.9	-0.1	-1.9	1.7	0.5	1.4	0.7	0.4
Leg fat percentage (left)	1.6	6.0	31.6	-1.3	-1.0	0.3	1.3	-1.5	1.5	-0.5	-2.8	5.6	3.6	-0.8	-0.3	-0.6	0.4	-1.5	2.3	-5.2	-2.1	-0.9	2.4	-4.2
Waist Hip Ratio (WHR)	1.5	6.6	42.8	-0.4	-0.5	-6.5	-6.2	-0.6	2.3	0.1	0.2	-5.8	0.6	1.0	-0.7	0.1	1.3	-1.9	-2.8	1.5	0.1	0.2	0.7	-0.2
Allergy or Eczema	1.5	4.1	7.7	-2.7	-2.4	0.6	0.7	-2.5	-2.0	-1.9	-0.1	-0.9	-0.5	-2.1	-2.4	-2.1	-1.8	-2.6	-1.3	-2.6	-2.8	-2.5	-2.3	-2.0
Diabetes (mother)	1.5	1.9	5.7	-1.7	-1.2	-1.3	-0.0	-1.7	1.9	0.2	0.3	0.1	1.6	0.0	-1.8	-0.7	0.0	-1.6	-1.2	-2.0	-1.8	-2.4	-1.0	-1.8
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	6.8	-0.9	-1.0	-1.8	-2.6	-1.0	-1.4	-0.1	-0.0	-2.0	-2.4	-1.9	-0.8	-1.3	-0.3	-0.7	-1.5	-0.8	-0.9	0.3	0.4	-1.1
Medication: Seretide 50 evohaler	1.5	1.8	6.2	-1.4	-0.9	-0.4	0.2	-2.3	1.2	-0.6	1.1	-0.9	-0.5	-1.3	-1.0	-1.1	-0.9	-1.4	-1.2	-2.5	-2.0	-1.0	-0.8	-2.2
Arm fat percentage (left)	1.5	6.1	28.5	-1.3	-0.8	0.6	1.5	-1.4	2.3	-0.4	-1.7	5.3	3.9	-0.7	0.3	-0.8	1.1	-1.6	2.8	-5.3	-1.9	-0.5	2.9	-4.1
Average weekly red wine intake	1.5	2.2	16.1	-0.1	-0.8	-1.0	-2.2	0.4	-1.8	0.3	-0.7	-2.7	-4.0	-2.7	-0.7	-1.1	-0.5	1.1	-1.1	0.2	-0.2	0.7	0.1	-1.0
Myopia	1.5	2.1	4.4	-1.4	-1.3	-1.2	-1.6	-1.9	-1.3	-0.6	1.0	-1.6	-1.4	-1.2	-1.3	-1.4	-0.8	-0.8	-1.7	-2.1	-1.9	-1.5	-1.6	-2.0
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	8.5	-1.1	-1.3	-2.9	-1.6	-0.1	1.0	-0.8	-0.4	-2.7	-0.6	-0.3	-1.2	-0.4	0.0	-1.8	-2.2	1.7	-0.0	-0.1	-1.1	0.0
Breast Cancer	1.4	3.3	15.6	-0.8	-1.5	0.8	1.6	-1.6	-0.1	-2.3	-2.1	3.5	-0.3	-1.7	-1.6	-0.8	-0.2	-0.8	0.0	-4.0	-2.2	-1.6	1.0	-2.8
Lupus	1.4	2.1	9.2	-1.0	-1.1	-0.6	-1.8	-1.5	0.4	-3.0	1.7	-2.4	-1.7	-0.9	-1.5	-1.2	-1.3	-1.2	-2.1	-0.4	-1.2	-1.0	-0.1	0.2
Systolic blood pressure, automated reading	1.4	3.9	27.2	-0.0	-0.3	-5.1	-3.8	-0.7	0.9	0.1	-0.2	-5.2	-0.9	-0.2	-0.6	0.1	1.4	-1.0	-2.5	0.6	-0.3	0.4	1.2	-1.0
Lung cancer (father)	1.4	1.6	3.9	1.9	1.4	1.0	0.2	1.3	-0.2	0.3	-0.5	-0.9	-1.7	0.2	1.6	1.4	0.1	1.8	0.6	1.7	1.6	2.0	1.2	1.3
Wears glasses or contact lenses	1.4	1.6	3.5	-1.5	-1.2	-1.6	-1.9	-1.4	0.1	-0.5	-0.3	-1.3	0.0	-0.6	-1.3	-1.1	-0.8	-1.4	-1.1	-1.7	-1.7	-1.5	-1.7	-1.2
Alcohol drinker status: Never	1.4	1.7	10.6	1.0	1.4	2.0	1.1	1.1	0.6	0.3	-0.3	3.3	0.7	1.2	1.3	0.5	0.1	1.5	1.5	1.0	1.4	1.0	1.6	1.1
Alzheimer’s Disease (in father)	1.3	1.4	6.4	0.7	0.9	2.5	2.5	0.9	0.5	0.6	1.6	0.3	0.3	0.4	1.2	0.9	-1.1	0.9	1.4	1.1	1.0	0.8	-0.7	0.8
Ulcerative Colitis (UC)	1.3	2.5	12.1	0.9	1.0	0.0	0.4	1.2	1.6	3.5	0.6	1.9	3.4	1.9	1.4	1.1	0.6	0.1	2.9	-0.3	0.9	0.7	1.1	-0.6
Coronary Artery Disease (CAD)	1.3	1.5	5.0	1.6	1.6	1.3	0.1	0.7	0.7	1.4	-1.3	2.2	0.8	1.0	1.4	1.8	-0.3	1.6	2.2	-0.1	1.0	0.7	0.6	0.2
Hayfever, allergic rhinitis or eczema	1.3	2.9	6.5	-2.3	-1.9	0.7	0.7	-2.2	-1.7	-1.5	-0.7	-0.6	0.3	-1.3	-1.9	-1.7	-1.6	-2.5	-0.7	-2.1	-2.4	-2.3	-2.3	-1.3
Impedance of arm (left)	1.3	6.0	12.9	2.8	2.8	-0.4	-1.4	2.8	2.2	2.3	1.2	-0.1	1.8	3.0	3.3	3.1	2.2	1.4	2.2	3.6	3.4	3.2	1.8	2.3
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	7.8	1.5	1.3	2.8	2.3	1.1	0.9	1.4	1.5	1.8	1.7	1.8	1.1	1.4	0.9	1.1	2.2	0.5	1.2	0.3	0.3	1.1
Commuting to job workplace: Car/motor vehicle	1.3	1.5	6.3	-0.7	-0.9	-0.4	-1.1	-0.7	-2.1	-0.9	-1.6	0.6	-2.5	-2.3	-0.6	-1.6	-1.2	-0.3	-1.4	-0.7	-0.8	0.2	-0.4	-0.7
Number of self-reported non-cancer illnesses	1.3	2.3	12.0	-1.8	-1.6	-3.5	-2.5	-1.4	-0.4	-0.5	0.6	-2.3	0.2	-0.7	-1.4	-0.8	0.5	-1.5	-1.8	-1.5	-1.4	-1.0	-0.0	-1.2
Medication: Atorvastatin	1.3	1.6	8.0	-1.9	-1.6	-0.0	0.1	-0.9	0.3	-1.9	0.1	-0.1	0.2	-0.5	-1.4	-1.1	-1.7	-2.0	-0.6	-0.2	-1.2	-1.6	-2.8	-0.1
Crohns Disease (2017)	1.2	2.6	13.5	0.5	0.6	0.3	-0.6	0.4	2.0	1.7	0.5	3.7	3.4	1.3	0.8	1.6	1.7	-0.6	2.9	-2.1	-0.1	-0.3	0.8	-0.8
Age at First Birth	1.2	1.7	4.9	1.7	1.6	2.2	1.8	1.0	0.1	0.4	-1.1	1.2	-0.0	1.1	1.6	1.8	-0.4	1.7	1.1	0.8	1.2	1.4	1.1	1.6
HDL Cholesterol	1.2	2.1	6.1	-1.3	-1.5	-0.5	0.2	-1.1	-1.6	-1.3	0.1	-1.7	-2.3	-1.3	-1.4	-2.0	-2.5	-0.9	-1.7	0.7	-0.9	-1.0	-2.4	0.1
Average weekly spirits intake	1.2	1.4	7.1	0.6	0.7	0.7	-1.6	0.3	-2.7	0.9	1.2	0.2	-0.5	0.1	1.3	0.8	2.3	1.1	0.4	0.3	0.9	1.5	1.7	1.3
Ever used hormone-replacement therapy (HRT)	1.2	1.5	6.1	-0.7	-1.1	-1.5	-1.9	-0.5	-0.1	0.1	1.2	-2.5	-2.2	-1.6	-1.1	-0.9	-0.7	-0.6	-2.1	0.2	-0.6	0.2	-0.5	-0.7
Financial difficulties in last 2 years	1.2	1.6	4.3	-1.4	-1.4	-0.7	-0.3	-2.1	0.8	-1.3	-0.9	-0.5	0.4	-0.2	-1.8	-1.4	0.7	-1.0	-1.7	-2.1	-1.8	-1.9	0.2	-0.8
Impedance of arm (right)	1.2	5.6	11.2	2.5	2.6	-0.5	-1.2	2.5	1.8	2.2	1.6	-0.2	2.2	3.1	3.3	2.7	2.5	1.1	2.1	3.4	3.2	3.2	1.9	2.2
Tense / ‘highly strung’	1.2	1.9	4.8	2.2	1.5	0.9	-0.3	1.4	-1.3	-1.3	-0.0	-2.0	-1.0	0.7	1.4	2.0	0.8	1.8	-0.0	1.3	1.5	1.5	1.1	2.2
Wheeze or whistling in the chest in last year	1.2	2.1	5.0	-1.8	-1.6	-1.7	-1.8	-1.5	-1.8	-0.2	-1.3	-0.4	-0.9	-1.9	-1.2	-1.8	-0.5	-0.9	-1.4	-2.1	-1.6	-0.2	0.5	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.3	5.4	-0.5	-0.6	-2.3	-2.3	-0.9	-0.0	-1.0	1.5	-2.0	-1.2	-0.2	-0.7	-0.1	-0.5	-0.8	-1.9	0.3	-0.6	-0.8	-0.9	0.6
Number of full sisters	1.2	1.4	4.1	-1.4	-1.4	-0.6	-0.1	-2.0	-1.3	-1.9	-0.8	0.6	-0.5	-1.3	-1.3	-1.1	-0.9	-1.0	-1.3	-1.7	-1.6	-1.2	-0.1	-0.5
Mother’s age at death	1.2	1.6	8.1	-0.2	0.6	1.1	1.8	0.8	1.0	1.8	-1.7	2.0	1.4	0.4	0.4	0.2	-2.8	0.4	1.9	-0.2	0.2	-0.4	-0.7	-0.9
Reaction Time	1.1	2.1	11.9	-1.2	-1.2	-0.5	-0.2	0.3	-2.6	-0.7	3.5	-3.1	-1.9	-1.4	-0.7	-1.5	-0.8	-0.0	-0.6	1.1	-0.0	0.1	-1.4	-0.2
Diabetes (father)	1.1	1.4	5.6	-0.7	-1.0	-1.6	-0.9	-1.8	-1.5	-0.9	0.9	-0.6	-2.0	-1.5	-0.9	-0.9	0.6	-0.9	-2.4	-0.5	-1.1	-0.1	0.5	-0.1
Leg fat-free mass (left)	1.1	5.8	18.6	-1.4	-1.6	-2.2	-4.2	-1.0	-4.0	-2.8	-0.1	-4.3	-4.3	-3.5	-1.2	-2.7	-1.0	-0.0	-2.7	-0.5	-1.0	0.3	0.4	-0.8
Leg predicted mass (left)	1.1	5.7	18.6	-1.4	-1.6	-2.2	-4.1	-1.0	-4.1	-2.8	-0.1	-4.2	-4.3	-3.5	-1.1	-2.7	-1.0	-0.0	-2.7	-0.5	-1.0	0.4	0.4	-0.8
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	4.6	-1.6	-1.1	-0.9	-0.9	-1.7	-1.1	-1.3	-0.5	-2.1	-0.2	-0.3	-1.0	-1.7	-0.2	-2.0	-1.6	-0.4	-1.1	-0.9	-1.1	-0.0
Pulse rate	1.1	1.8	6.1	-2.0	-0.9	-1.1	0.5	-1.4	1.2	-0.3	1.2	-1.5	1.7	0.5	-1.0	-1.3	-2.5	-1.7	-0.7	-0.6	-1.2	-1.9	-1.7	-1.2
Peak expiratory flow (PEF)	1.1	2.7	17.3	-1.3	-1.4	-2.6	-2.8	-0.3	-0.8	-1.3	-0.1	-4.2	-1.1	-1.0	-1.6	-1.8	-0.9	-0.3	-2.3	1.2	-0.3	-0.8	-1.3	-0.4
Body fat percentage	1.1	4.3	19.3	-0.7	-0.4	-0.0	0.4	-0.9	1.7	-0.2	-2.1	4.4	3.4	-0.4	0.6	-0.3	0.7	-1.1	2.4	-4.1	-1.2	0.3	3.2	-3.5
Qualifications: College or University degree	1.1	3.3	10.9	-2.2	-2.0	-1.1	-0.8	-2.1	1.0	-1.0	0.7	-3.3	-0.5	-1.3	-2.4	-1.5	-1.1	-1.6	-2.0	-1.9	-2.4	-2.6	-1.9	-1.9
Medication: Omeprazole	1.1	1.3	5.4	-0.4	-0.7	-2.3	-1.4	0.6	0.6	-0.5	-0.3	-2.3	-1.2	-0.3	-0.5	-0.1	-0.0	-1.0	-1.6	2.3	0.6	0.7	-1.0	0.2
Chest pain or discomfort	1.1	1.6	4.8	-2.2	-1.7	-1.0	-0.7	-1.0	-1.1	-0.7	0.2	-0.1	0.1	-0.8	-1.8	-2.0	-1.3	-1.6	-1.2	-1.0	-1.3	-1.7	-1.6	-0.3
Leg fat-free mass (right)	1.1	5.9	21.6	-1.2	-1.4	-2.1	-4.2	-1.0	-4.4	-2.5	0.1	-4.7	-4.5	-3.5	-1.1	-2.7	-1.0	0.2	-2.8	-0.4	-0.9	0.4	0.5	-0.4
Leg predicted mass (right)	1.1	6.0	21.9	-1.2	-1.4	-2.0	-4.3	-1.0	-4.4	-2.5	0.1	-4.7	-4.6	-3.5	-1.1	-2.7	-1.0	0.2	-2.8	-0.4	-0.9	0.4	0.4	-0.4
Ever taken oral contraceptive pill	1.1	1.2	3.0	-1.3	-1.4	-0.3	0.2	-1.2	-1.0	-1.4	0.0	-1.4	-0.9	-0.9	-1.4	-1.5	-0.1	-1.3	-1.7	-0.6	-1.2	-1.2	-1.4	0.0
Commuting to job workplace: Public transport	1.1	1.4	5.2	-0.6	-0.1	1.0	1.7	-0.2	2.3	2.1	1.3	0.0	2.2	1.5	-0.4	0.1	-0.7	-0.4	1.1	0.0	-0.3	-1.3	-1.1	-0.8
Commuting to job workplace: Cycle	1.1	1.4	7.5	-1.4	-0.7	-0.8	0.2	-1.4	2.7	-1.3	0.9	-0.5	2.0	0.4	-0.8	-0.6	-0.6	-1.8	-0.3	-0.9	-1.1	-1.3	-0.2	-1.2
Crohns Disease (2012)	1.0	1.6	9.2	-0.6	-0.2	-0.2	-0.8	-1.0	1.4	-0.1	1.3	1.8	3.0	1.3	-0.3	0.8	1.3	-1.1	1.1	-2.1	-0.8	-1.8	0.3	0.2
Lung FEV1/FVC ratio	1.0	5.0	28.8	0.7	1.6	1.1	3.4	0.2	4.0	0.3	1.6	2.2	5.4	3.2	1.2	2.0	1.6	-0.0	3.1	-1.9	0.3	-1.0	1.7	0.5
Vitamin and mineral supplements	1.0	1.4	11.3	-0.0	0.6	0.6	0.9	0.5	3.4	0.5	-0.3	2.3	2.5	1.3	0.4	0.4	-0.4	-0.2	0.3	-0.9	0.3	-0.1	0.7	-0.2
Average weekly fortified wine intake	1.0	1.2	5.0	-0.9	-0.3	1.1	0.9	-1.2	1.0	-0.6	2.2	-0.2	2.2	1.2	-0.4	-0.2	0.8	-1.0	0.3	-0.8	-0.8	-1.5	-0.8	1.0
Qualifications: CSEs or equivalent	1.0	1.4	8.2	0.2	0.2	-0.1	-1.1	-0.8	-1.3	-0.6	-1.9	2.2	0.2	-0.3	0.4	0.4	2.9	-0.1	-0.5	-1.5	-0.4	0.6	2.1	-0.0
Serious illness, injury or assault to yourself	1.0	1.2	7.0	-1.2	-1.0	-0.5	0.3	-1.0	1.2	-1.3	2.6	-0.5	0.3	-0.2	-1.0	0.0	-1.2	-1.2	-0.9	-0.5	-1.1	-1.3	-1.7	-0.5
Illnesses of mother	1.0	1.2	9.2	0.1	0.1	3.0	1.9	-0.4	1.1	-1.7	0.7	1.4	-0.6	0.5	-0.4	0.2	0.3	0.5	-0.2	0.0	-0.1	-1.0	-0.6	1.9
Pulse wave Arterial Stiffness index	1.0	1.1	5.6	-0.3	-0.3	-0.4	-1.4	-0.8	-1.8	-0.0	-0.5	-1.8	-2.4	-1.5	-0.4	-0.7	1.0	0.7	-1.4	-0.9	-0.7	-0.1	0.7	0.1
Medication: Amlodipine	1.0	1.4	7.2	0.8	0.0	-2.0	-1.2	0.1	0.0	-2.1	-0.4	-2.7	-1.9	-0.8	0.0	0.3	0.6	0.1	-1.3	0.1	0.2	1.2	1.8	-0.6
High blood pressure (siblings)	1.0	1.4	6.3	0.4	-0.0	-2.5	-2.5	0.8	-1.5	-0.4	-0.3	-2.0	-1.3	-0.9	0.6	0.5	1.3	0.5	-0.6	1.2	0.7	1.6	0.7	-0.0
Mean time to correctly identify matches	1.0	1.9	12.7	-0.1	-0.2	0.4	0.7	1.2	-1.9	-0.3	3.6	-2.9	-2.1	-0.7	0.1	-0.5	-0.8	0.9	-0.1	2.0	0.9	1.0	-0.8	0.5
Family relationship satisfaction	1.0	1.2	3.8	1.1	0.7	0.7	0.2	1.0	-1.4	-0.0	1.1	-0.8	-0.3	1.2	0.6	1.2	1.6	1.3	0.1	1.6	1.3	0.7	1.2	1.9
Pack years of smoking	1.0	1.4	6.7	1.3	1.1	0.9	-0.1	0.3	-0.7	0.2	0.8	1.4	0.7	1.0	1.2	1.4	2.1	0.8	0.9	-0.1	0.8	1.1	2.6	1.8
Impedance of whole body	1.0	5.0	14.0	2.6	2.6	-0.6	-1.6	2.5	2.1	2.2	0.3	-0.3	1.6	3.1	2.6	2.9	1.4	1.4	1.4	3.7	3.1	2.6	1.4	2.6
Bipolar Disorder (2018)	0.9	1.4	12.1	-0.8	-0.5	-3.5	-3.1	-0.4	-0.5	0.2	0.3	-1.3	0.4	-0.5	0.2	0.0	0.9	-1.2	-0.3	-0.4	-0.3	0.6	0.2	-1.0
Schizophrenia vs Biploar Disorder	0.9	1.2	5.5	0.1	0.1	1.4	2.3	-0.7	0.9	-0.6	0.5	0.7	1.8	1.6	-0.6	0.8	0.7	-0.7	0.3	-0.8	-0.7	-2.0	-0.8	0.9
Alzheimer’s Disease (in mother)	0.9	1.1	2.7	-1.5	-1.6	-1.0	-0.9	-0.4	-0.5	0.0	0.7	-0.6	-0.4	-1.4	-1.4	-1.1	-1.4	-0.8	-1.0	-0.6	-1.0	-0.9	-1.4	-1.3
Body Mass Index (BMI) (2010)	0.9	1.2	5.5	-0.7	-0.5	0.7	1.1	-0.8	0.8	0.4	0.8	2.3	1.6	-0.2	-0.5	-0.3	0.2	-0.9	1.3	-2.1	-1.2	-1.2	-0.6	-1.3
Mean Putamen Volume	0.9	1.0	2.5	0.9	1.4	0.1	0.2	1.3	-0.1	1.3	-0.1	-0.3	1.0	1.2	1.3	0.0	-0.5	0.9	0.8	1.4	1.6	1.5	1.3	0.9
Triglycerides	0.9	1.4	4.2	-1.6	-1.3	-1.7	-1.8	-1.3	0.6	-1.5	-0.5	-0.6	0.6	-0.2	-1.7	-0.9	0.3	-1.3	-2.1	-1.1	-1.2	-1.5	-0.3	0.1
Sensitivity / hurt feelings	0.9	1.5	6.2	1.1	1.0	2.2	1.5	0.6	0.7	-0.2	2.5	0.3	0.5	0.8	0.9	1.5	1.6	1.3	1.2	-0.1	0.8	0.7	1.5	1.3
High blood pressure (mother)	0.9	1.2	9.6	-0.0	-0.1	-3.1	-2.3	-0.3	-1.0	0.5	-0.5	-1.4	-0.2	-0.6	0.1	-0.3	1.1	-0.5	-0.4	-0.6	-0.4	0.6	1.2	-1.5
Had other major operations	0.9	1.1	2.4	-1.6	-1.4	-1.1	-0.6	-1.2	-0.9	0.3	1.3	-0.8	-0.3	-0.9	-1.3	-1.4	-1.0	-1.1	-1.1	-0.9	-1.2	-0.8	-0.3	-1.3
Pain all over the body in last month	0.9	1.0	2.9	-0.8	-0.9	-1.7	-1.4	-1.3	0.5	0.2	0.1	-1.6	0.2	0.4	-1.2	-1.1	-0.0	-0.9	-1.7	-0.5	-0.9	-1.1	0.3	-0.4
Weight	0.9	4.5	15.1	-1.7	-1.8	-2.7	-3.9	-1.4	-2.4	-2.6	-1.3	-2.0	-2.4	-3.4	-1.1	-2.6	-0.7	-0.9	-1.8	-2.1	-1.5	0.3	1.5	-2.4
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.6	-1.2	-1.0	1.2	1.5	-0.9	0.1	-0.4	-0.9	1.5	1.2	-0.1	-1.2	-0.9	-1.0	-1.1	0.3	-1.0	-1.0	-1.6	-1.1	-0.2
Arm fat mass (right)	0.9	3.5	20.0	-1.7	-1.4	-0.8	-0.9	-1.8	0.2	-1.5	-1.5	2.1	1.3	-2.0	-0.5	-1.7	0.6	-1.6	0.5	-4.5	-2.1	-0.3	2.6	-3.5
Number of full brothers	0.9	1.2	3.3	-1.6	-1.4	-1.2	0.5	-0.9	-0.0	0.9	1.1	0.2	1.2	-0.4	-1.3	-1.1	0.0	-1.2	0.0	-1.1	-1.3	-1.4	-1.4	-1.8
Emphysema/chronic bronchitis	0.9	1.1	3.8	-1.3	-0.9	-1.4	-0.1	-1.4	-1.3	-1.9	1.1	-0.7	0.9	-0.1	-0.8	-0.5	-0.5	-1.6	-0.7	-1.0	-1.1	-1.1	-0.7	-0.1
Heart disease (mother)	0.9	1.0	6.4	0.8	0.7	-2.5	-1.7	0.9	-0.9	0.8	-1.0	-0.4	-0.1	-0.1	1.1	0.6	0.0	0.3	0.7	0.5	0.8	1.7	1.0	-1.0
Leg fat mass (right)	0.9	3.4	16.6	-1.5	-1.4	-0.5	-0.5	-1.4	-0.3	-1.6	-2.6	3.1	1.2	-1.9	-0.6	-1.4	0.1	-1.2	0.8	-4.1	-1.9	-0.4	2.1	-3.5
Osteoporosis (self-reported)	0.9	1.1	5.5	-1.2	-0.7	-2.1	-2.4	-0.9	-0.6	0.1	-1.3	-0.4	-0.1	-0.7	-0.7	-1.2	-0.7	-0.5	-1.1	-1.3	-1.0	-0.3	0.5	-0.4
Arm fat mass (left)	0.9	3.8	21.3	-1.8	-1.6	-0.8	-0.8	-1.9	0.1	-1.6	-1.8	2.1	1.0	-2.2	-0.7	-1.9	0.2	-1.5	0.5	-4.6	-2.3	-0.4	2.5	-3.7
Leg fat mass (left)	0.9	3.4	17.5	-1.4	-1.3	-0.5	-0.4	-1.4	-0.4	-1.4	-2.6	3.1	1.3	-1.8	-0.6	-1.4	0.1	-1.1	0.8	-4.2	-1.9	-0.5	2.2	-3.5
Bipolar Disorder (2011)	0.8	0.8	3.9	-0.3	-0.2	-1.4	-2.0	-0.3	-1.4	0.0	0.0	-1.6	-1.0	-0.7	-0.4	-0.3	1.0	-0.2	-1.4	-0.4	-0.3	0.2	0.9	0.1
Supplements: Zinc	0.8	0.9	3.1	0.7	0.4	1.4	0.7	0.9	-0.0	0.6	1.8	-1.4	-0.3	0.5	0.0	0.5	-0.6	0.9	0.8	1.3	0.7	-0.5	-1.4	1.4
Medication: Metformin	0.8	1.1	4.2	-0.9	-0.2	-0.2	1.0	-0.8	1.8	1.6	0.8	0.9	1.8	-0.0	-0.2	-0.4	0.9	-0.7	-0.3	-2.0	-0.9	-0.4	0.7	-1.8
Nervous feelings	0.8	1.4	6.9	1.5	1.3	2.6	1.5	0.3	0.5	-1.3	0.1	-0.3	0.1	1.4	0.7	1.9	-0.7	0.5	-0.0	1.2	0.8	0.3	-0.2	2.5
Illnesses of siblings	0.8	1.1	3.3	-1.4	-0.7	1.1	0.8	-0.8	1.0	-0.5	1.1	-0.1	0.1	-0.2	-1.1	-1.8	-1.8	-1.4	-0.6	-0.3	-0.9	-1.4	-1.7	0.0
Neuroticism score	0.8	1.6	4.0	1.7	1.2	2.0	1.4	0.7	0.6	-1.2	-1.4	-0.1	0.5	1.4	1.0	1.4	1.5	1.4	0.6	0.4	1.1	0.8	2.0	1.9
Alcohol intake versus 10 years previously	0.8	1.2	3.3	1.5	1.3	0.6	0.6	1.0	-1.8	0.0	-1.2	0.7	-0.4	0.5	1.7	0.8	-0.5	1.4	1.1	0.9	1.3	1.5	1.0	0.9
Worrier / anxious feelings	0.8	1.4	5.6	1.1	0.8	2.1	1.1	0.7	-0.1	-1.3	0.9	-2.2	-1.1	0.9	0.3	1.0	-0.0	1.1	-0.3	1.7	1.0	0.2	-0.1	2.4
Medication: Cholesterol lowering	0.8	1.2	3.3	-1.7	-1.2	-1.4	-0.6	-1.3	0.1	-1.2	-1.8	0.1	0.2	-0.6	-1.0	-1.3	-1.2	-1.4	-1.2	-0.8	-1.1	-0.9	-0.6	-0.9
Breastfed as a baby	0.8	1.0	2.7	1.3	1.4	0.1	-0.3	1.3	-1.0	0.5	0.5	-0.7	-1.0	0.4	1.2	0.2	-0.5	1.6	0.0	1.4	1.4	1.4	0.8	1.3
Pulse wave reflection index	0.8	1.0	4.0	-0.4	-0.8	-0.2	-1.1	-0.7	-2.0	0.6	-1.8	0.2	-1.8	-1.6	-0.7	-0.9	0.7	-0.1	-0.9	-1.4	-1.0	-0.0	0.0	-0.8
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	5.1	-1.8	-1.5	-0.0	-1.3	-1.2	-2.1	-0.9	-0.8	1.4	-0.2	-1.4	-0.9	-1.4	-0.2	-1.0	-0.8	-2.3	-1.5	-0.8	-0.3	-0.5
Chronic bronchitis/emphysema (mother)	0.8	0.9	4.2	-0.7	-0.9	-1.3	-2.0	-0.3	-1.2	-1.2	-1.6	-1.3	-1.2	-1.2	-0.5	-0.8	0.3	-0.2	-1.0	0.1	-0.3	0.2	-0.1	0.0
Health satisfaction	0.8	1.1	2.6	1.1	0.8	0.5	-0.3	1.2	0.1	-0.3	0.1	-1.2	-0.2	0.6	1.0	1.4	1.4	1.4	0.6	1.6	1.5	1.5	1.1	1.3
Neck or shoulder pain in last month	0.8	1.2	7.0	0.9	0.6	1.4	0.6	1.2	0.6	-0.1	-1.9	2.6	0.2	0.2	0.9	0.7	-0.1	1.5	0.9	0.0	1.0	1.3	1.6	-0.1
Had major operations	0.8	0.9	3.5	-0.4	-0.3	1.4	-0.0	-0.1	-1.4	-0.3	1.9	-1.4	-1.7	-0.6	-0.4	-0.8	-0.9	1.1	-0.5	0.6	0.0	-0.3	-0.6	1.4
Friendships satisfaction	0.8	1.0	5.9	0.7	0.8	1.7	0.9	1.0	-1.0	0.8	2.4	-0.2	0.1	1.0	0.7	0.7	0.3	1.7	0.6	0.5	0.9	0.3	0.6	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.1	-1.0	-1.0	0.4	-0.2	-0.7	-0.5	-1.2	1.4	-1.8	-0.9	-0.7	-1.7	-0.4	0.1	-0.4	-1.6	-0.3	-0.8	-1.3	-0.1	1.1
Osteoarthritis (self-reported)	0.8	1.0	4.2	-0.7	-1.1	-1.3	-0.8	-1.0	-0.3	-0.1	-1.2	1.2	-0.2	-1.4	-0.6	-0.8	0.5	-1.6	-0.5	-1.2	-1.1	0.1	-0.1	-2.0
Illnesses of father: None of the above (group 1)	0.8	1.0	3.4	-0.4	0.4	1.8	1.5	0.3	1.6	0.6	-0.5	1.6	1.6	1.2	-0.3	0.1	-1.1	0.2	1.1	-0.4	0.1	-1.2	0.0	0.5
Miserableness	0.8	1.3	14.1	0.6	0.1	1.3	1.2	1.0	-1.3	-0.5	-3.7	1.3	-0.5	-0.5	0.3	-0.4	0.8	1.3	0.6	-0.3	0.6	0.8	1.2	-0.2
Cholesterol lowering medication	0.8	1.1	4.6	-0.2	-0.2	-1.8	-2.1	-0.5	0.6	-2.1	1.1	-2.1	-0.2	-0.1	-0.5	0.6	0.4	0.2	-1.6	-0.6	-0.2	-0.1	1.3	0.2
Alzheimer’s Disease (including proxy)	0.7	1.0	3.6	-1.3	-1.6	-0.2	-0.4	-0.5	-0.5	-0.7	1.6	-0.6	-0.8	-1.2	-1.1	-0.6	-1.6	-0.9	-0.6	0.1	-0.8	-0.9	-1.9	-0.6
Neuroticism	0.7	1.6	3.8	1.9	1.1	1.9	1.3	1.1	0.8	-1.1	-1.9	-0.7	-0.8	0.7	1.1	1.4	0.4	1.5	0.4	1.4	1.4	1.5	1.0	1.4
Chronotype (morning person)	0.7	1.7	4.3	1.7	1.4	-2.0	-1.7	0.1	-0.4	-0.4	0.4	-1.8	0.2	1.7	0.7	2.1	1.7	0.8	-0.8	1.0	0.7	0.3	1.6	1.9
Relative age of first facial hair	0.7	1.4	7.5	0.1	-0.4	1.0	2.1	-0.5	2.5	-0.4	-0.9	2.7	0.7	0.6	-0.5	0.8	-1.8	-0.5	0.8	-0.0	-0.4	-1.2	-1.4	-0.4
Pack years adult smoking proportion	0.7	1.1	6.6	1.1	0.8	0.7	-0.4	0.1	-1.2	0.4	0.3	1.5	0.4	0.5	0.9	1.1	2.1	0.7	0.7	-0.5	0.4	0.9	2.6	1.3
Trunk fat percentage	0.7	2.9	12.0	-0.3	-0.0	-0.7	-0.6	-0.6	1.4	0.0	-1.6	3.0	2.9	-0.2	0.9	-0.2	0.9	-1.0	2.1	-3.1	-0.7	0.9	3.5	-2.8
Townsend deprivation index at recruitment	0.7	1.0	4.2	0.4	0.8	-1.1	-0.5	0.9	0.2	1.3	0.0	0.0	1.4	1.3	0.9	0.3	1.0	1.1	0.9	1.0	1.4	1.0	2.1	0.6
Waist circumference	0.7	2.4	9.1	-1.3	-1.1	-2.1	-2.7	-1.1	0.3	-1.4	-1.5	0.4	1.1	-1.4	-0.4	-1.3	0.1	-1.4	0.0	-3.0	-1.4	-0.0	2.0	-2.9
Medication: Lansoprazole	0.7	0.8	5.4	-0.9	-0.1	-0.4	-0.4	-0.9	1.8	-0.1	0.0	1.0	2.3	1.5	-0.1	0.4	0.9	-0.9	-0.4	-0.6	-0.3	-0.7	0.7	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	3.6	1.2	1.0	0.6	1.4	0.6	1.2	0.0	-0.8	-0.1	1.6	1.7	0.2	1.4	0.8	0.9	0.4	0.1	0.8	0.1	1.9	0.9
Hair/balding pattern: Pattern 4	0.7	1.7	4.6	1.2	1.4	0.4	0.4	0.6	0.6	0.9	-0.9	1.4	1.5	1.6	2.1	1.3	1.8	0.7	2.1	0.8	1.2	1.6	1.7	1.0
Birth weight	0.7	1.6	11.5	0.4	0.8	-1.4	-0.8	0.5	2.6	-0.1	0.2	-3.4	-0.5	0.7	-0.1	0.0	0.2	0.1	-1.8	1.3	0.8	0.5	1.3	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	4.1	1.1	1.0	0.9	0.8	0.1	1.6	-0.2	1.0	-0.9	0.7	2.0	0.3	1.0	0.3	0.7	-0.2	0.9	0.7	-0.2	1.0	1.6
Number of children fathered	0.7	0.8	4.5	0.3	0.0	-0.8	-1.1	-0.6	-0.5	-1.0	-1.8	-0.8	-2.1	-1.1	-0.3	0.1	0.3	0.7	-0.8	-0.5	-0.4	0.2	1.0	-0.4
Migraine (self-reported)	0.7	0.8	3.7	0.8	0.8	0.5	-0.1	1.1	-0.1	1.0	-0.8	1.4	-0.6	-0.1	0.8	0.2	0.8	1.7	0.8	0.4	0.9	1.2	1.9	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.1	-1.3	-1.2	-0.7	-1.1	-0.9	0.4	-0.8	0.1	-0.8	-0.8	-0.9	-1.1	-0.8	-0.5	-1.5	-1.3	0.0	-0.8	-0.6	-1.4	-0.1
Ever had bowel cancer screening	0.7	0.8	2.5	0.8	0.5	0.6	0.8	1.5	1.3	0.2	0.9	-1.6	-0.2	0.7	0.3	1.4	-0.2	1.0	0.3	1.2	1.1	0.5	-0.2	0.5
Qualifications: nursing, teaching	0.7	1.1	4.2	-1.1	-1.0	-0.7	0.1	-1.0	1.3	0.2	2.0	-0.6	1.2	-0.2	-0.8	-0.3	-0.8	-1.7	0.1	-0.8	-1.2	-1.3	-1.1	-1.6
Breast cancer (self-reported)	0.7	0.8	7.4	-0.6	-0.8	-0.3	-0.4	-0.5	-2.7	0.3	-0.4	-0.6	-1.0	-1.4	-0.4	-0.9	-0.2	-0.2	-0.3	-0.7	-0.7	0.2	-0.0	-1.6
Verbal and Numeric Reasoning (VNR)	0.6	1.4	4.5	0.9	1.1	1.9	2.1	0.8	1.9	0.4	1.5	0.9	0.8	0.5	1.1	1.1	0.5	1.1	1.6	-1.0	0.4	0.6	1.9	-0.8
Rheumatoid Arthritis	0.6	0.9	4.4	0.8	1.1	1.6	1.0	0.4	0.7	-0.4	0.1	1.2	0.7	1.3	0.7	0.9	1.0	0.6	0.4	0.4	0.7	-0.1	0.9	2.1
Type 2 Diabetes (T2D) (2012)	0.6	0.6	5.5	0.2	-0.5	-0.2	-0.6	-0.7	-0.8	-2.3	0.0	-0.1	-1.0	-0.6	-0.9	-0.1	0.1	-0.8	-1.6	-0.1	-0.4	-0.2	0.7	0.1
Blood White Count	0.6	4.4	19.9	-0.8	-0.3	-3.4	-2.1	-0.6	-0.3	0.1	-4.5	4.4	3.3	0.3	-0.0	-0.7	-0.2	-0.8	1.4	-3.0	-1.1	-0.9	0.9	-3.1
Respiratory disease	0.6	1.4	7.5	-1.5	-1.1	-0.1	1.1	-1.4	-0.3	0.0	-0.8	-0.2	0.3	-1.2	-1.0	-0.9	-1.2	-1.1	-0.1	-2.0	-1.6	-0.9	-1.2	-2.7
Angina	0.6	0.7	6.4	-0.4	-0.3	0.5	-0.3	0.3	-0.7	0.3	-2.3	2.5	0.4	-0.4	0.1	0.0	0.1	0.4	0.2	-1.2	-0.2	-0.1	0.1	-0.2
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	3.3	-0.6	-0.6	0.1	0.4	-0.0	-1.1	-1.2	-1.8	0.7	-1.1	-1.4	-0.3	-1.0	-0.4	-0.6	-0.6	-0.2	-0.3	0.2	-0.6	-0.7
Multivitamins +/- minerals	0.6	0.8	4.8	0.1	-0.3	-0.3	-0.4	-0.1	-1.8	0.0	1.3	-2.2	-1.9	-0.7	-0.3	-0.2	0.5	0.5	-0.4	1.0	0.0	0.1	-0.5	0.2
Medication: Levothyroxine sodium	0.6	1.0	2.8	-1.6	-1.3	-1.1	-1.7	-1.1	-0.4	-0.6	-0.5	0.4	0.4	-0.9	-0.8	-0.8	-0.5	-1.3	-0.9	-1.5	-1.2	-0.7	-0.4	-0.8
Number of incorrect matches in round	0.6	1.0	5.4	1.5	0.6	-0.7	-0.6	0.5	-1.0	-0.6	-0.3	-2.3	-1.3	0.5	0.1	0.8	-0.8	0.4	-1.4	1.5	0.6	0.3	-0.7	1.3
Allergy	0.6	1.4	3.2	1.7	0.9	-0.8	-1.1	1.6	1.6	0.9	-0.0	0.4	-0.9	0.6	0.9	0.9	1.6	1.6	0.1	1.8	1.5	1.4	1.6	0.8
Fluid intelligence score	0.6	1.3	8.5	0.2	0.5	1.9	2.9	0.4	2.1	0.1	1.7	0.9	1.2	0.9	0.3	0.5	-0.2	0.7	1.3	-0.2	0.3	-0.4	1.0	-0.3
Birth weight of first child	0.6	1.2	5.0	-0.2	-0.4	-1.7	-1.9	0.0	-1.1	0.4	-0.2	-2.2	-2.1	-1.1	-0.4	-0.6	0.3	-0.0	-1.6	1.3	0.3	0.8	0.0	-0.1
Exposure to tobacco smoke outside home	0.6	0.8	4.1	1.0	0.9	0.3	0.1	0.8	-0.2	-1.3	-0.8	0.7	-0.5	0.2	1.0	0.5	0.7	1.0	0.2	0.6	1.1	1.3	2.0	0.9
Worry too long after embarrassment	0.6	1.1	8.5	0.7	0.8	0.6	0.7	-0.3	2.9	-0.9	0.6	-0.2	1.7	1.9	0.3	0.9	0.7	-0.1	0.6	-0.2	0.1	-0.6	0.8	1.0
Pulse wave peak to peak time	0.6	0.7	2.4	0.4	0.3	0.0	0.5	1.0	1.2	-0.2	0.4	0.8	1.4	1.2	0.5	0.6	-1.2	-0.4	0.9	1.5	1.0	0.5	-0.7	0.3
Angina (self-reported)	0.6	0.8	8.2	-0.2	-0.2	0.9	0.0	0.4	-0.6	0.3	-2.2	2.9	0.8	-0.1	0.3	0.2	0.1	0.5	0.4	-1.2	-0.0	0.0	0.2	-0.1
Whole body fat mass	0.6	2.5	12.3	-1.2	-1.0	-0.9	-1.5	-1.3	-0.3	-1.5	-1.8	1.6	0.9	-1.8	-0.2	-1.4	0.0	-1.1	0.6	-3.5	-1.5	0.2	2.6	-3.0
Illnesses of siblings: Diabetes	0.6	0.7	3.3	0.6	0.5	0.3	0.7	0.2	-0.9	0.6	1.8	0.0	0.3	0.0	1.2	1.4	1.6	0.2	0.9	0.8	0.7	1.1	0.1	0.1
Loneliness, isolation	0.6	0.8	3.1	-0.5	-0.8	1.0	0.6	-0.7	-0.6	0.2	-0.7	1.6	0.2	-0.6	-0.7	-1.2	1.0	0.5	0.1	-1.8	-0.8	-0.3	1.1	-1.4
Medication: Aspirin	0.6	0.7	2.8	0.3	0.1	-0.9	-1.1	1.3	-1.0	-0.3	-0.7	0.1	-1.4	-0.6	0.3	-0.6	-1.3	0.7	-0.4	1.7	1.0	1.1	-0.4	0.1
Smoking status: Current	0.6	1.0	3.4	0.8	0.7	0.0	-0.2	1.1	-1.8	-0.1	-1.4	1.8	0.7	0.4	1.3	0.3	0.5	1.0	1.2	0.2	1.0	1.5	1.5	-0.0
Average weekly beer plus cider intake	0.6	0.8	4.6	-1.2	-0.8	0.3	-0.1	-0.8	-2.1	-0.1	-1.7	0.1	0.3	-1.0	-0.7	-0.5	0.3	-0.6	-0.1	-1.6	-1.0	-0.7	-0.3	-0.7
Risk taking	0.6	0.9	4.7	0.6	0.0	1.1	0.8	0.3	-1.8	-0.7	0.7	-1.5	-2.2	-0.5	-0.2	0.2	0.8	1.1	-0.6	1.0	0.4	0.2	0.4	1.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	4.8	0.7	0.4	0.6	1.2	0.3	1.2	0.7	2.2	-0.9	0.2	1.2	0.1	0.6	0.0	0.8	0.3	0.9	0.4	-0.6	-1.1	0.8
Age started oral contraceptive pill	0.6	0.7	2.2	-0.8	-1.0	0.3	1.0	-0.7	1.3	0.3	-0.1	0.1	0.4	-0.4	-1.4	-0.2	-0.6	-0.6	-0.4	-1.0	-1.0	-1.5	-1.2	-1.1
Unable to work because of sickness or disability	0.6	0.8	5.1	-0.7	-0.5	-1.9	-2.3	-0.9	0.3	0.8	-0.2	0.2	1.1	0.2	-0.0	-0.1	0.6	-0.8	-0.4	-1.1	-0.5	0.1	0.9	-0.4
Supplements: Calcium	0.6	0.7	2.7	-1.1	-0.3	-0.3	-0.3	-0.5	-0.4	-1.1	-0.1	-0.9	1.4	1.2	-0.9	-0.2	0.6	-0.9	-0.2	0.1	-0.4	-1.6	-0.5	1.5
Depressed Affect (Nagel 2018)	0.5	1.0	10.4	0.6	0.1	1.0	1.6	-0.1	1.1	-1.7	-3.2	1.0	-0.3	-0.1	-0.0	0.1	0.3	0.7	0.1	-0.2	-0.0	0.1	0.5	-0.3
Neuroticism (Nagel 2018)	0.5	1.3	4.2	1.6	1.1	1.7	2.0	0.5	1.0	-1.3	-1.4	-0.7	-0.0	1.2	0.8	1.4	0.9	1.0	0.2	1.0	0.9	0.6	0.7	1.4
Heel T-Score	0.5	4.2	53.3	-0.1	0.0	4.7	7.3	0.2	-1.3	-0.0	0.3	2.1	-0.8	-0.6	-0.3	-0.6	-0.7	0.3	0.8	0.6	-0.0	-0.5	-1.6	0.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	3.2	-0.4	-0.3	-1.2	-1.1	-0.8	1.6	-0.0	1.8	-0.1	0.9	1.0	-0.6	0.5	0.6	-0.7	-0.9	-0.4	-0.5	-0.9	0.1	0.4
Impedance of leg (right)	0.5	2.4	10.7	1.6	1.4	-1.5	-2.1	1.8	1.6	0.7	-1.3	-0.6	0.5	1.9	1.3	2.0	0.3	0.6	-0.1	3.3	2.2	1.8	0.5	1.6
Current tobacco smoking	0.5	0.8	3.3	0.6	0.5	0.2	-0.3	0.8	-1.7	0.1	-1.5	1.8	0.5	0.1	1.1	0.2	0.4	0.8	0.9	-0.1	0.8	1.4	1.4	-0.2
Maternal smoking around birth	0.5	0.7	7.6	0.6	0.2	0.2	-0.4	0.9	-0.0	0.1	-2.8	0.2	-0.5	-0.1	0.2	0.8	0.6	1.1	-0.2	0.6	0.7	0.7	1.0	0.3
Relative age voice broke	0.5	0.8	2.9	-0.5	-0.7	0.1	1.2	-0.8	1.3	-1.5	0.4	1.3	0.5	0.7	-1.1	-0.2	-0.4	-1.1	-0.5	0.3	-0.5	-1.7	-1.3	0.6
Taking other prescription medications	0.5	0.8	3.8	-1.5	-0.5	-1.9	-1.0	-1.1	1.3	0.4	0.8	0.2	1.4	0.3	-0.3	-0.3	-0.3	-1.2	-0.7	-1.1	-0.8	-0.2	0.3	-0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.5	-0.9	-0.7	-0.5	0.6	-0.7	0.6	0.3	0.8	-0.1	0.9	0.0	-1.0	-0.7	-0.2	-0.5	-0.7	-1.0	-0.9	-1.2	-0.8	-1.1
Impedance of leg (left)	0.5	2.2	8.6	1.6	1.4	-1.4	-2.1	1.6	1.2	1.1	-1.5	-0.6	0.5	1.9	1.2	1.9	0.0	0.7	-0.2	2.9	2.0	1.6	0.5	1.7
Had menopause	0.5	0.6	3.8	0.1	-0.2	-1.9	-1.0	-0.2	1.4	0.6	1.5	-1.0	0.4	0.3	-0.3	0.5	-0.2	-0.8	-0.6	0.3	-0.1	-0.0	-0.1	-0.5
Diabetes (self-reported)	0.5	0.7	3.2	-0.8	-0.3	0.2	0.5	-1.3	0.6	-0.2	0.2	0.3	0.9	-0.1	-0.6	-0.5	1.5	-0.9	-1.3	-1.8	-1.1	-0.6	1.1	-0.5
Hip circumference	0.5	2.1	8.1	-1.4	-1.2	0.5	-1.0	-0.8	-1.7	-0.9	-1.1	2.2	-0.1	-2.5	-0.2	-1.8	-0.0	-0.7	0.8	-2.8	-1.3	0.4	1.5	-2.5
Asthma	0.5	1.0	4.8	-1.1	-0.7	-0.3	-0.2	-1.2	0.5	0.8	-0.6	-0.5	-0.3	-1.4	-0.7	-0.6	-1.1	-0.6	-0.3	-2.1	-1.4	-0.5	-0.6	-2.2
Length of working week for main job	0.5	0.6	1.4	0.7	0.5	-0.5	-1.0	0.9	-0.7	0.5	0.2	-1.1	-0.5	-0.0	0.5	0.1	0.9	0.8	0.0	1.2	0.9	1.0	0.9	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.6	0.7	0.5	0.2	0.4	-0.1	1.0	-1.1	-0.4	1.2	1.6	1.2	0.3	0.7	0.6	0.4	0.1	-0.5	0.2	-0.4	1.0	-0.1
Medication: Aspirin	0.5	0.7	2.4	0.2	0.0	-0.5	-0.7	1.1	-1.1	-0.6	-1.0	0.2	-1.2	-0.5	0.2	-0.7	-1.5	0.7	-0.4	1.6	0.9	0.9	-0.4	0.1
Supplements: Vitamin C	0.5	0.6	4.7	0.3	0.1	-0.0	-0.4	0.3	-2.2	-0.6	0.9	-1.1	-0.8	-0.1	0.3	-0.1	0.6	0.2	0.4	1.2	0.5	0.4	-0.3	1.4
Eye problems/disorders: Cataract	0.5	0.6	3.6	-0.1	-0.6	-0.6	-0.5	0.7	0.4	-0.5	-1.0	-1.9	-1.4	-0.7	-0.5	-0.3	-0.8	0.2	-0.7	1.2	0.4	0.3	0.0	0.1
Mineral and other dietary supplements	0.5	0.7	6.5	0.1	0.4	0.6	0.9	0.3	0.5	-0.2	-0.8	2.5	1.9	0.9	0.3	0.5	-0.3	0.1	0.7	-0.5	0.3	-0.2	0.7	0.3
Asthma (self-reported)	0.5	1.1	5.9	-1.1	-0.7	-0.2	0.0	-1.3	0.3	0.6	-0.7	-0.3	-0.1	-1.3	-0.7	-0.7	-1.0	-0.6	-0.3	-2.4	-1.5	-0.6	-0.4	-2.2
Average weekly champagne plus white wine intake	0.5	0.8	2.9	-0.7	-0.2	-0.9	-0.1	0.1	0.8	-0.7	1.2	-1.2	1.7	0.9	-0.4	-0.5	-1.4	-0.8	0.6	0.2	-0.1	-1.2	-1.3	-0.4
Pain experienced in last month	0.5	0.8	2.5	0.4	0.7	-0.8	0.6	-0.1	1.4	0.6	1.6	-1.1	1.3	1.1	0.4	1.6	0.9	-1.0	0.6	0.3	-0.0	-0.4	-0.9	0.7
Heart disease (siblings)	0.5	0.6	3.2	0.9	0.2	0.9	1.6	0.0	0.2	0.4	-0.4	1.8	0.5	0.8	0.1	1.2	0.6	1.0	0.6	-0.6	0.0	-0.2	0.7	-0.6
Depression (Nagel 2018)	0.4	0.5	2.6	0.4	-0.2	-0.0	-0.1	-1.0	0.9	-1.6	-0.4	-1.0	-0.8	0.1	-0.3	-0.0	0.9	-0.5	-1.6	-0.0	-0.5	-0.2	0.2	1.1
Prostate Cancer	0.4	0.5	3.4	-0.6	0.2	-0.4	0.2	-0.4	0.4	0.7	1.1	1.1	1.0	-0.2	0.1	-0.2	0.6	0.3	0.5	-1.5	-0.3	0.1	1.8	-0.4
LDL Cholesterol	0.4	0.6	2.7	-0.1	0.1	0.7	1.5	-0.3	1.6	-1.2	-0.0	0.0	0.9	1.0	-0.4	-0.1	-1.0	-0.4	-0.2	-0.0	-0.2	-1.0	-0.2	0.6
Primary Biliary Cirrhosis	0.4	0.5	5.5	-0.1	0.2	-0.6	-0.4	0.5	0.7	-0.2	0.4	0.3	0.8	0.3	0.3	0.5	2.3	0.1	0.7	-0.1	0.5	0.3	1.0	0.7
Blood Eosinophil Count	0.4	3.0	12.4	1.6	2.0	-0.8	0.3	0.8	2.3	3.5	-0.7	1.8	2.5	1.1	2.6	1.6	-0.2	0.6	2.5	-0.6	1.0	2.1	0.8	-2.1
Tanning	0.4	4.6	10.8	1.8	2.3	-2.0	-3.3	2.6	0.4	3.0	-1.4	0.3	1.6	2.5	2.4	2.1	-0.2	2.7	2.0	3.0	2.9	2.3	1.6	1.0
Severe depression (siblings)	0.4	0.5	3.3	-0.3	-0.0	-0.0	0.2	-0.6	-0.5	0.3	1.4	0.1	1.8	0.7	0.2	0.0	1.1	-0.4	0.7	-1.3	-0.4	-0.3	0.4	-0.5
Trunk fat mass	0.4	1.9	7.5	-0.8	-0.6	-1.5	-2.0	-0.9	-0.1	-1.4	-1.4	0.8	0.8	-1.4	0.2	-1.1	0.1	-1.0	0.5	-2.6	-1.0	0.7	2.7	-2.4
Past tobacco smoking	0.4	0.7	3.2	-0.6	0.1	-0.1	0.1	-0.3	1.8	0.8	0.8	0.2	1.7	1.4	-0.6	-0.1	-0.4	-0.5	-0.2	-0.6	-0.4	-1.5	-0.9	-0.2
Alcohol usually taken with meals	0.4	0.6	4.1	-0.5	-0.4	-0.8	-2.0	0.1	0.1	-0.2	0.8	-1.0	-0.7	-0.3	-1.0	-0.4	0.2	0.2	-0.9	-0.4	-0.5	-1.2	-0.5	0.5
Medication: Simvastatin	0.4	0.5	2.8	0.1	0.0	-1.4	-1.1	-0.4	0.7	-1.1	0.7	-0.6	-0.3	-0.1	0.1	0.3	0.3	0.5	-1.2	-0.3	-0.0	0.5	1.7	-0.5
Father’s age at death	0.4	0.5	4.1	-0.3	-0.7	-0.4	0.1	-0.1	-0.1	0.3	0.6	-0.2	-0.8	-0.3	-0.7	-0.6	-1.0	-0.4	-0.1	0.1	-0.5	-0.7	-2.0	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	4.6	0.0	-0.0	0.4	0.8	0.0	0.0	0.1	0.6	0.9	1.6	0.7	0.2	0.4	2.1	-0.0	-0.1	-1.1	0.1	0.3	1.7	0.6
Falls in the last year	0.4	0.5	3.1	0.2	0.0	-0.6	-0.8	0.2	1.8	1.6	-0.1	-1.1	0.4	0.3	-0.3	0.7	0.8	0.5	0.4	-0.3	0.0	-0.1	0.7	-0.9
Loud music exposure frequency	0.4	0.5	2.0	-0.1	-0.3	-0.3	0.1	-0.9	0.5	-0.2	-0.4	-1.1	0.4	0.9	-0.8	0.2	0.5	-0.4	-0.9	-0.7	-0.7	-1.4	-0.8	0.6
Gout (self-reported)	0.4	0.5	2.5	-0.3	-0.1	0.3	1.0	-0.3	0.8	-0.3	1.6	-0.1	1.0	0.7	-0.4	0.2	-1.2	0.1	0.5	-0.3	-0.3	-1.3	-0.9	0.0
Age at first live birth	0.4	0.8	3.7	-0.0	-0.1	1.4	1.9	-0.2	0.3	-1.6	-0.6	-0.6	-0.5	0.2	-0.7	-0.4	-1.1	-0.3	-0.6	0.4	-0.3	-1.2	-1.7	0.6
Age at last live birth	0.4	0.5	1.6	0.3	0.5	0.3	0.9	0.8	-1.0	0.3	-1.0	-1.1	-0.8	-0.1	0.5	-0.7	-0.8	0.8	0.6	1.3	0.6	0.1	-1.1	0.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.8	0.5	0.7	1.3	1.0	-0.0	0.4	-1.0	1.7	-0.2	0.3	0.5	0.2	0.6	0.1	0.8	0.8	0.2	0.3	-0.2	0.4	0.2
Diabetes diagnosed by doctor	0.4	0.6	3.9	0.1	0.2	0.3	0.5	-0.6	0.5	-0.4	1.2	0.3	0.6	0.2	-0.1	0.3	2.0	-0.1	-1.0	-1.3	-0.4	-0.1	1.6	-0.0
Back pain experienced in last month	0.4	0.6	2.8	-0.4	-0.2	0.2	-1.6	0.4	-1.7	-1.2	-1.1	1.0	-0.3	-0.5	0.3	-0.2	0.5	0.4	0.0	0.3	0.4	0.6	0.5	0.8
Medication: Gliclazide	0.4	0.4	2.6	0.5	0.7	-0.5	-1.3	-0.4	0.3	1.0	0.4	-0.3	0.2	-0.2	0.7	0.1	0.9	0.4	-0.1	-0.8	-0.0	0.7	1.6	0.0
Ever smoked	0.4	0.7	4.8	0.7	-0.1	-0.3	-0.6	-0.3	-2.2	-1.2	-1.1	-0.1	-1.5	-1.3	0.4	0.2	0.8	0.0	-0.3	-0.1	-0.1	1.1	0.9	0.3
Fractured/broken bones in last 5 years	0.4	0.5	3.3	0.2	-0.2	-1.1	-1.6	0.3	-0.3	-0.0	-1.8	-0.4	-0.3	-0.3	-0.1	0.3	-0.2	0.8	-0.5	-0.3	0.0	0.2	0.6	-0.5
Alcohol drinker status: Previous	0.4	0.4	2.4	-0.6	-0.8	-0.6	-0.6	-0.6	-0.1	-0.4	-1.6	0.2	-0.3	-0.4	-0.8	-0.9	-1.0	-0.4	-0.8	-0.2	-0.6	-0.5	-0.3	-0.3
Bipolar Disorder or Schizophrenia	0.3	0.7	3.9	-0.1	-0.4	-1.5	-2.0	-0.7	-1.6	-0.6	-1.1	-0.9	-0.3	-0.4	0.0	0.8	1.2	-0.8	-0.6	-0.2	-0.3	0.3	0.2	0.6
Schizophrenia (2018)	0.3	0.6	3.0	0.5	-0.1	1.0	-0.1	-0.6	-1.6	-0.9	-1.7	-0.2	-0.7	-0.1	-0.2	1.0	1.0	-0.2	-0.6	0.0	-0.2	-0.2	-0.2	1.6
Schizophrenia (2014)	0.3	0.6	2.7	0.9	0.6	-0.0	-0.5	0.1	-1.2	0.2	-0.7	-0.1	0.5	1.0	0.6	1.6	1.6	-0.1	0.6	0.5	0.4	0.2	0.1	1.4
Blood Red Count	0.3	3.3	24.6	0.2	0.2	-5.0	-4.4	-0.0	0.9	-1.1	-1.4	2.0	1.4	0.3	0.1	-0.0	1.9	-1.3	-0.7	-0.7	0.0	0.7	2.0	-2.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	5.5	-0.2	-0.1	-0.7	-0.5	-0.2	0.3	-0.2	1.0	-0.6	0.1	-0.4	0.1	0.2	2.4	-0.4	-1.1	-0.6	-0.1	0.5	1.3	-0.2
Hair Pigment	0.3	8.9	19.5	4.2	3.6	3.1	1.7	3.0	4.0	-2.4	-1.1	3.9	1.5	3.1	3.4	4.4	1.2	3.5	3.4	1.6	3.1	2.0	2.6	2.6
Ever had hysterectomy (womb removed)	0.3	0.3	0.9	0.5	0.2	-1.0	-0.9	0.4	-0.5	-0.2	0.4	-0.8	-0.7	0.3	0.1	-0.1	-0.4	0.7	-0.5	0.7	0.6	0.6	0.6	0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.4	-0.5	0.1	0.2	0.9	-0.3	-0.0	0.0	1.2	-0.9	-0.0	-0.4	-0.3	-0.7	-0.9	0.2	-0.5	-0.7	-0.4	-0.3	0.8	-0.2
Fed-up feelings	0.3	0.6	5.0	-1.0	-1.0	0.9	0.7	-0.1	-0.5	0.1	-2.2	1.2	0.3	-0.5	-0.8	-0.9	-0.2	0.3	0.1	-0.2	-0.3	-0.6	-0.1	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	2.6	0.6	0.4	0.3	0.1	0.1	-0.1	-1.2	0.3	-0.5	-0.2	0.7	0.3	-0.2	0.4	0.3	-0.8	0.7	0.6	0.5	0.7	1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	6.0	-0.7	-0.7	1.6	2.4	0.0	-1.1	0.8	1.3	0.9	0.1	-0.4	-0.6	-0.0	0.7	-0.2	0.1	0.0	-0.2	-0.3	-0.1	0.5
Mouth/teeth dental problems	0.3	0.4	2.7	-0.6	-0.5	-0.1	-0.4	-0.0	-1.4	-0.1	-0.4	0.4	-1.6	-1.1	-0.5	-0.7	-0.2	0.0	-0.5	0.0	-0.4	-0.3	-0.9	0.1
Hair/balding pattern: Pattern 3	0.3	0.5	2.0	-1.0	-0.7	-0.8	-0.6	-0.6	-1.4	-0.7	-0.2	-0.7	-0.1	-0.3	-0.8	-1.2	-0.2	-0.5	-1.3	-0.4	-0.6	-0.7	-0.4	0.0
Number of live births	0.3	0.4	2.6	-0.3	0.1	-1.0	-1.3	0.4	0.7	1.6	0.2	-0.5	0.3	-0.1	0.2	-0.3	-0.1	0.4	0.2	-0.1	0.2	0.4	0.1	-0.9
Depression (self-reported)	0.3	0.3	3.8	0.8	0.2	-0.3	0.2	-0.0	0.2	0.5	0.1	-0.6	-0.4	0.4	0.1	0.5	1.9	0.0	-0.3	0.5	0.3	0.7	0.8	0.2
Prospective memory result	0.3	0.4	1.5	0.3	0.2	-0.9	-0.1	-0.8	1.0	-0.9	-0.3	0.5	1.2	0.8	-0.2	0.5	0.0	-0.8	0.3	-0.8	-0.5	-0.8	-0.0	-0.6
Ever highly irritable/argumentative for 2 days	0.3	0.3	2.2	-0.0	0.1	-0.4	0.0	-0.6	0.3	-1.3	-0.4	-0.3	-0.1	-0.1	0.2	0.1	-1.5	-0.2	0.1	-0.9	-0.5	0.0	0.0	-0.5
Glaucoma (self-reported)	0.3	0.3	1.1	-0.3	-0.4	-0.6	0.6	-0.8	0.2	-0.6	-0.2	-0.7	0.0	-0.0	-0.4	-0.2	-0.2	-0.9	0.5	-0.5	-0.8	-0.6	-1.0	-1.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.7	0.5	0.7	-0.4	0.4	0.0	-0.1	1.0	-0.4	-0.2	-0.3	-0.2	1.0	0.1	-1.3	0.6	1.0	0.0	0.2	1.1	-0.0	-1.1
Eye problems/disorders: None of the above	0.3	0.3	2.5	0.1	0.3	0.4	-0.1	0.1	-1.0	0.8	-0.9	1.6	0.1	-0.2	0.5	-0.1	-0.3	0.2	0.4	-0.3	0.1	0.3	-0.4	-0.8
Medication: Allopurinol	0.3	0.5	1.7	0.5	0.4	0.6	1.1	0.8	1.3	0.4	1.1	-0.6	0.0	0.4	0.2	0.7	-0.5	1.0	0.5	1.0	0.7	0.1	-0.4	0.0
Overall health rating	0.3	0.6	2.9	0.0	0.4	-1.1	-1.5	0.4	0.4	0.8	0.5	-0.0	1.3	0.5	0.7	0.6	0.5	-0.1	0.1	-0.1	0.5	1.1	1.7	-0.1
Smoking status: Previous	0.3	0.4	3.0	0.1	-0.4	0.2	0.0	0.1	-0.8	-0.1	-0.2	-0.6	-1.7	-1.5	0.2	0.0	-0.0	0.1	-0.1	0.6	0.1	1.0	0.2	0.1
Mood swings	0.3	0.6	6.3	0.3	0.2	0.2	0.1	0.4	0.9	-2.5	-1.1	-0.1	0.4	0.7	0.3	0.1	-0.4	0.8	-0.3	0.9	0.7	0.2	0.3	1.1
Long-standing illness, disability or infirmity	0.3	0.5	3.2	-0.5	-0.0	0.2	-0.1	-0.7	-0.1	-0.1	0.3	1.4	1.8	0.6	0.0	0.5	-0.4	-0.4	0.2	-1.6	-0.5	-0.7	0.2	-0.2
Guilty feelings	0.3	0.4	1.6	0.2	-0.3	0.9	0.3	-0.1	-0.1	-1.2	-0.8	0.4	1.2	0.9	-0.7	-0.3	0.5	-0.1	-0.1	-0.4	-0.0	-0.7	0.9	0.6
Financial situation satisfaction	0.3	0.3	3.4	0.1	0.0	-0.1	-0.0	-0.4	-1.3	-1.0	-1.9	0.1	-0.5	-0.1	0.1	-0.3	-0.2	-0.1	-0.4	-0.2	-0.3	0.1	0.1	-0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.2	0.6	0.4	-0.2	0.1	0.1	0.9	0.9	0.9	-1.5	-1.2	-0.1	0.4	0.5	-0.5	0.3	-0.0	1.0	0.2	0.5	-0.7	-0.3
High cholesterol (Self-reported)	0.3	0.6	3.0	-0.7	-0.3	-1.6	-0.8	-0.5	1.5	-0.8	-1.7	0.2	0.5	0.1	-0.1	0.1	-0.6	-0.4	-0.5	-0.0	-0.1	0.3	1.1	-0.7
Irritability	0.3	0.5	1.9	0.6	0.1	0.3	0.7	0.8	-1.4	-0.3	-0.7	-0.4	0.1	0.0	0.6	0.9	0.9	0.9	0.5	0.1	0.6	0.8	1.1	0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.3	2.2	-0.0	-0.0	1.0	0.5	0.2	-0.9	-0.2	0.2	1.5	-0.8	-0.3	0.3	-0.4	-0.1	0.2	0.3	0.0	0.1	0.2	-1.3	0.4
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.2	-1.1	-0.6	0.1	0.5	-0.2	1.8	-0.8	1.2	0.8	1.3	-0.3	-0.4	-0.6	-0.3	-0.6	0.6	-1.2	-0.5	-0.6	0.1	-1.4
Blood Platelet Count	0.2	2.3	10.8	1.1	1.3	3.1	3.3	0.9	2.2	0.2	-0.4	0.9	1.3	1.5	0.4	1.9	-0.3	1.8	1.6	-0.3	0.7	-0.3	1.3	0.9
Smoking Status	0.2	0.5	3.3	-0.2	-0.5	0.3	0.4	-0.1	-1.6	0.7	-0.6	1.8	0.2	-0.8	0.3	-0.4	-0.2	-0.1	0.9	-0.6	-0.2	0.6	0.3	-1.0
Hypothyroidism (self reported)	0.2	0.6	2.4	-1.0	-0.7	-0.4	-1.3	-0.6	-1.0	-0.1	0.2	1.2	0.9	-0.2	-0.1	-0.6	0.7	-0.6	-0.3	-1.5	-0.6	-0.1	0.8	-0.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	0.5	-0.2	-0.7	-0.5	0.0	-0.2	-1.0	-0.5	-0.7	-0.7	-0.3	0.2	-0.1	1.0	0.1	-0.8	0.5	0.2	0.8	0.8	-0.1
Medication: Co-codamol	0.2	0.3	1.7	-0.1	-0.1	-0.2	-0.2	-0.5	-0.6	1.3	0.2	0.4	-0.2	-0.3	-0.1	0.3	0.1	0.3	0.3	-1.2	-0.6	-0.3	0.1	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.3	-0.1	-0.3	-1.5	-1.4	0.1	-0.4	-1.1	-0.1	-0.6	0.2	0.3	-0.3	-0.4	0.3	-0.1	-0.7	0.3	0.2	0.2	0.7	-0.1
Hair/balding pattern: Pattern 2	0.2	0.2	1.8	0.3	-0.2	-0.4	-0.7	-0.2	0.6	-0.1	-0.0	-0.1	0.2	-0.1	-0.3	-0.0	1.3	-0.3	-0.3	-0.7	-0.4	-0.4	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.0	-0.1	-0.2	0.3	1.2	0.4	-1.4	1.3	0.2	0.9	-1.0	-1.1	0.3	-0.3	0.8	0.5	-0.1	0.2	0.3	1.1	1.0	-0.3
Qualifications: None of the above	0.2	0.5	1.9	1.0	0.8	0.2	0.2	0.6	-0.5	-0.3	-0.1	1.1	-0.2	0.6	0.9	0.4	-0.2	0.3	0.5	1.4	1.0	1.1	0.0	1.2
Heart attack	0.2	0.3	2.4	-0.2	-0.1	0.9	0.3	0.1	-0.6	0.0	0.4	1.5	-0.4	-0.1	0.2	-0.4	0.1	0.1	0.3	-0.1	-0.0	0.1	-1.1	0.4
Happiness	0.2	0.3	2.3	-0.4	-0.5	-0.5	-0.4	-0.1	-1.5	-0.4	-0.1	-0.1	0.5	-0.1	-0.4	-0.4	0.8	0.4	-0.3	-0.5	-0.2	-0.3	0.9	-0.5
Noisy workplace	0.2	0.3	1.0	-0.1	0.2	-0.6	0.0	-1.0	0.0	-0.3	-0.4	-0.7	-0.4	-0.3	-0.3	-0.1	0.7	-0.2	-0.9	-0.7	-0.5	-0.2	0.9	-0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.5	6.1	-0.1	-0.2	0.4	-0.6	0.2	0.4	-0.8	1.2	-2.5	-0.9	-0.5	-0.4	-0.2	0.2	0.2	-0.8	0.2	-0.1	-0.3	-0.6	-0.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	2.0	-0.5	-0.2	-0.5	-1.3	0.1	-0.4	-0.1	0.8	-1.4	-0.3	-0.6	-0.2	-0.3	0.1	0.1	-0.4	-0.6	-0.2	-0.1	0.6	-0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	2.3	0.2	-0.1	0.5	-0.1	0.3	0.4	-0.7	-1.5	-0.3	0.1	-0.1	-0.2	0.5	-0.2	0.7	-0.2	-0.3	0.1	0.1	0.5	-0.1
Headache pain in last month	0.2	0.4	1.7	-0.8	-0.5	-0.5	-1.1	0.0	0.6	0.9	-0.3	0.2	1.3	0.1	-0.5	-0.8	-0.0	0.3	0.0	-0.7	-0.2	-0.5	0.8	-0.5
Shortness of breath walking on level ground	0.2	0.3	1.7	-0.0	-0.1	-0.4	-0.8	0.0	-0.8	0.8	-1.3	0.7	-0.4	-0.7	0.2	-0.1	0.5	-0.5	-0.1	-0.3	-0.2	0.7	0.0	-0.5
Illnesses of father: Heart disease	0.2	0.3	1.9	-0.1	-0.1	-0.3	-0.0	-0.5	-0.0	-0.1	0.4	1.4	1.1	0.6	0.2	0.5	0.8	-0.4	0.1	-0.1	-0.2	-0.3	-0.3	0.6
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	0.5	0.6	0.0	0.3	0.1	0.1	-0.5	-0.1	0.1	0.2	0.6	0.7	0.5	0.4	0.2	0.9	0.5	0.4	0.5	0.1	0.6
Basal cell carcinoma (self-reported)	0.2	0.3	1.5	-0.6	-0.6	0.2	0.4	0.0	-0.8	0.4	1.2	0.1	0.8	0.2	-0.4	-0.0	-0.6	-0.2	0.3	0.1	-0.2	-0.5	-1.1	-0.2
Leg pain on walking	0.1	0.1	1.1	-0.4	-0.6	-0.0	-0.5	0.1	-1.0	0.3	-0.1	-0.1	-0.0	-0.1	-0.3	0.1	0.2	-0.1	-0.1	-0.0	-0.0	-0.2	-0.6	0.1

Hub : Genes

NCOA1

Models

Trait associations