Best TWAS P=4.97e-14 · Best GWAS P=1.85e-38 conditioned to 7.59e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | CommonMind | Brain Pre-frontal Cortex | STAT4 | 0.07 | 0.06 | lasso | 2 | 0.04 | 9.4e-06 | 7.9 | 7.5 | 5.0e-14 | 0.28 | 0.98 | 0.00 | TRUE |
| 1 | CommonMind | Brain Pre-frontal Cortex | NAB1 | 0.06 | 0.06 | lasso | 2 | 0.04 | 4.3e-06 | 6.2 | -6.5 | 1.1e-10 | -0.23 | 0.97 | 0.00 | TRUE |
| 3 | GTEx | Breast Mammary Tissue (Female) | INPP1 | 0.16 | 0.02 | lasso | 4 | 0.03 | 5.2e-02 | 4.8 | -6.0 | 1.6e-09 | -0.09 | 0.01 | 0.78 | FALSE |
| 6 | GTEx | Testis | NAB1 | 0.14 | 0.06 | enet | 20 | 0.10 | 5.1e-05 | 4.3 | 5.8 | 5.1e-09 | 0.25 | 0.73 | 0.03 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | NAB1 | 0.05 | 0.02 | blup | 50 | 0.04 | 2.9e-03 | -3.5 | -5.7 | 1.6e-08 | -0.16 | 0.03 | 0.30 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TMEM194B | 0.04 | 0.01 | blup | 41 | 0.02 | 3.8e-03 | 4.9 | 5.5 | 3.4e-08 | 0.13 | 0.01 | 0.90 | FALSE |
| 7 | GTEx | Thyroid | AC005540.3 | 0.09 | 0.07 | enet | 5 | 0.04 | 2.5e-04 | 3.9 | -5.4 | 7.4e-08 | -0.19 | 0.77 | 0.04 | FALSE |
| 5 | GTEx | Esophagus Mucosa | GLS | 0.07 | 0.01 | lasso | 6 | 0.01 | 5.4e-02 | 6.0 | 5.3 | 1.0e-07 | 0.12 | 0.11 | 0.03 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | TMEM194B | 0.13 | 0.12 | enet | 13 | 0.11 | 6.9e-09 | -3.9 | 5.2 | 2.6e-07 | 0.14 | 1.00 | 0.00 | FALSE |