Hub : Genes

MB21D2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1100 0.0370 4.4e-04 0.110 NA 0.087 NA 0.107 3.0e-09 NA 1.5e-07 NA 5.0e-09
2 GTEx Adipose Visceral Omentum 0.1310 0.0510 5.7e-03 0.014 NA 0.083 NA 0.033 5.9e-02 NA 4.3e-05 NA 8.0e-03
3 GTEx Adrenal Gland 0.2792 0.0706 1.8e-05 0.310 NA 0.286 NA 0.341 9.1e-12 NA 8.3e-11 NA 5.5e-13
4 GTEx Cells EBV-transformed lymphocytes 0.7330 0.0670 1.6e-11 0.556 NA 0.591 NA 0.629 1.6e-21 NA 1.6e-23 NA 7.0e-26
5 GTEx Cells Transformed fibroblasts 0.2860 0.0570 2.0e-07 0.210 NA 0.204 NA 0.214 1.1e-15 NA 3.0e-15 NA 5.1e-16
6 GTEx Esophagus Mucosa 0.1420 0.0480 1.5e-03 0.034 NA 0.022 NA 0.027 2.4e-03 NA 1.3e-02 NA 6.3e-03
7 GTEx Lung 0.0779 0.0314 6.9e-03 0.074 NA 0.016 NA 0.053 2.5e-06 NA 2.1e-02 NA 6.4e-05
8 GTEx Thyroid 0.1060 0.0410 5.3e-03 0.001 NA 0.000 NA 0.001 2.7e-01 NA 3.0e-01 NA 2.4e-01
9 METSIM Adipose 0.0519 0.0242 1.4e-02 0.036 0.011 0.028 0.022 0.030 4.1e-06 0.0064 3.9e-05 0.00028 2.1e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.8 1.2 2.8 1.7 0.5 0.6 0.2 1.4 1.7 1.7 0.1 -0.5
Bipolar Disorder or Schizophrenia 0.4 0.9 2.4 0.8 1.3 0.0 0.2 1.3 1.1 0.8 1.5 -0.3
Depressed Affect (Nagel 2018) 0.7 1.4 5.6 -0.2 -0.4 2.4 -0.3 -1.0 0.2 -0.2 -0.8 2.2
Depression (Nagel 2018) 1.3 2.0 3.5 -1.6 -1.9 -1.2 0.3 -1.4 -1.2 -1.6 -1.6 1.3
Intelligence (Savage-Jansen 2018) 1.6 4.8 9.5 2.7 0.6 -1.8 -2.4 0.2 2.8 2.7 3.1 -1.5
Neuroticism (Nagel 2018) 0.8 2.0 4.6 -1.6 -1.7 0.8 0.2 -1.2 -1.1 -1.6 -2.2 1.4
Schizophrenia (2018) 0.3 0.7 3.9 -0.3 1.3 -0.5 0.0 0.6 0.1 -0.3 2.0 0.1
Schizophrenia vs Biploar Disorder 2.2 2.8 7.2 -2.7 -0.3 -1.6 1.1 -0.3 -2.6 -2.7 0.4 0.3
Worry (Nagel 2018) 0.5 1.0 3.3 -0.5 -1.5 -0.1 0.6 -1.4 -0.4 -0.5 -1.8 0.6
Alzheimer’s Disease (in mother) 1.6 1.8 3.7 -1.9 1.2 -0.2 -0.3 -1.8 -1.7 -1.9 -1.0 -0.8
Alzheimer’s Disease (in father) 0.6 0.6 2.4 -0.2 1.3 -0.9 -0.6 -0.6 -0.2 -0.2 0.2 1.6
Alzheimer’s Disease (including proxy) 0.8 1.1 3.0 -1.2 1.2 -0.3 -1.0 -1.7 -1.2 -1.2 -0.4 -0.4
Crohns Disease (2017) 1.3 2.8 5.8 2.0 1.8 0.1 -2.4 -0.5 1.1 2.0 2.1 -1.5
Irritable Bowel Disease (IBD) 1.5 3.6 9.1 2.4 1.4 1.1 -3.0 -1.1 1.4 2.4 1.8 -1.5
Ulcerative Colitis (UC) 0.7 1.3 3.5 1.5 0.3 1.2 -1.9 -0.2 0.9 1.5 0.8 -0.7
Major Depression (MDD) 0.1 0.2 0.7 0.2 -0.4 0.3 -0.3 -0.8 0.4 0.2 -0.4 0.5
Reaction Time 1.7 3.2 8.1 -1.7 -0.4 -2.1 1.6 -0.4 -2.8 -1.7 -0.9 2.5
Verbal and Numeric Reasoning (VNR) 1.9 4.6 9.2 3.0 0.5 -0.8 -2.5 0.7 2.9 3.0 2.7 -0.3
Breast Cancer 1.5 3.6 11.0 2.4 0.6 3.3 -1.5 1.0 2.2 2.4 1.0 0.7
Ovarian Cancer 0.3 0.3 1.2 0.0 0.8 1.1 0.3 -0.9 0.3 0.0 -0.4 -0.4
Prostate Cancer 0.4 0.5 2.8 -0.4 -0.0 -0.3 1.7 1.0 -0.6 -0.4 0.1 -0.5
Age at First Birth 0.4 0.5 3.0 -0.1 -0.4 -0.6 1.7 0.6 -0.7 -0.1 0.3 0.4
Bipolar Disorder (2011) 1.5 1.5 4.7 1.8 -0.4 0.6 -0.4 0.6 2.2 1.8 1.0 0.0
Body Mass Index (BMI) (2010) 1.2 1.6 3.5 1.6 1.5 -1.2 -0.9 0.5 1.9 1.6 1.0 0.5
Coronary Artery Disease (CAD) 0.7 0.8 2.4 0.4 1.3 1.0 -1.2 0.6 0.2 0.4 1.6 0.1
Crohns Disease (2012) 1.3 2.1 4.6 2.0 0.3 -0.6 -2.1 0.2 1.3 2.0 1.4 -1.5
Mean Putamen Volume 0.4 0.5 1.6 -0.4 -0.6 1.3 -0.1 -1.1 -0.1 -0.4 1.0 0.4
Fasting Glucose 0.2 0.2 0.7 -0.2 0.6 -0.7 -0.2 0.1 -0.0 -0.2 0.8 0.6
HbA1C 0.4 0.4 0.9 0.9 0.2 -0.9 0.1 -0.0 0.2 0.9 0.7 -0.6
HDL Cholesterol 0.7 1.1 5.1 -0.8 -1.3 0.8 2.3 0.0 -1.0 -0.8 -0.1 0.4
LDL Cholesterol 0.2 0.3 0.7 -0.7 0.0 0.2 0.4 0.5 -0.8 -0.7 -0.5 -0.0
Lupus 0.3 0.4 0.8 0.8 0.6 -0.3 0.0 -0.8 0.8 0.8 0.9 0.0
Neuroticism (2016) 0.5 0.7 2.3 -0.4 -1.5 0.8 0.4 -0.2 -0.9 -0.4 -1.3 -0.9
Primary Biliary Cirrhosis 1.0 1.4 5.8 -0.6 0.1 -1.8 -1.4 -2.4 -0.7 -0.6 -0.0 0.7
Rheumatoid Arthritis 3.6 5.0 12.5 2.5 2.6 0.8 -3.5 -2.0 2.1 2.5 1.9 1.1
Schizophrenia (2014) 0.3 0.6 2.8 -0.4 0.8 -1.2 -0.3 0.4 -0.2 -0.4 1.7 -0.2
Triglycerides 0.4 0.7 3.2 -0.2 0.7 -0.1 -1.8 -0.5 -0.2 -0.2 -1.3 -0.2
Type 2 Diabetes (T2D) (2012) 1.6 1.8 5.3 1.7 1.9 -0.4 0.1 -0.9 0.7 1.7 0.5 -2.3
Ulcerative Colitis 0.5 0.7 2.0 1.0 -0.1 0.3 -1.3 -0.3 0.6 1.1 1.4 -0.0
Blood Eosinophil Count 0.2 1.4 3.2 0.2 0.0 -1.6 1.8 0.2 -0.8 0.2 -1.8 -1.6
Blood Platelet Count 0.1 1.2 2.9 -1.7 0.1 0.2 0.1 -1.4 -0.9 -1.7 -0.7 -1.1
Blood Red Count 0.3 2.4 4.8 2.2 -0.4 -1.2 -0.8 2.2 1.8 2.2 1.6 -0.2
Blood White Count 0.1 0.8 2.8 0.1 0.5 -1.7 0.3 -1.0 -0.4 0.1 -0.0 1.6
Heel T-Score 0.1 0.5 2.4 -0.1 0.0 -0.9 1.6 -0.1 -0.4 -0.1 -0.4 -0.9
BMI 0.5 3.0 5.6 1.9 1.4 -0.0 -2.1 0.3 1.9 1.9 2.1 2.4
Height 0.1 1.9 6.0 -1.3 -0.1 -2.4 1.6 0.4 -0.8 -1.3 -1.1 -1.9
Waist Hip Ratio (WHR) 0.1 0.6 3.9 -0.0 0.8 0.3 -0.7 -0.6 -0.0 -0.1 -0.6 -2.0
Systolic Blood Pressure 0.3 1.5 4.5 1.0 1.3 -2.1 -1.5 0.5 0.3 1.0 1.1 -1.1
Smoking Status 0.3 0.7 1.6 0.8 0.6 1.2 -0.9 -0.5 0.7 0.8 -1.0 0.4
Allergy or Eczema 0.4 1.1 3.8 0.6 0.7 1.2 2.0 1.5 0.0 0.6 0.6 -0.7
Cardiovascular Disease 0.6 2.1 4.4 2.0 0.3 -0.5 -2.1 0.2 2.1 2.0 0.2 1.5
Hypothyroidism (self reported) 3.4 7.8 29.5 3.3 2.9 0.2 -5.4 -0.2 2.7 3.3 1.4 0.9
Respiratory disease 0.7 1.6 11.2 -0.8 0.6 -0.5 3.3 -0.1 -1.2 -0.8 0.0 0.1
Type 2 Diabetes (T2D) (2018) 0.5 1.0 3.8 -1.0 0.5 -2.0 -0.5 -1.2 -0.7 -1.0 0.4 -0.5
Lung FEV1/FVC ratio 0.6 2.9 7.2 -1.6 -1.8 1.9 0.6 -1.4 -1.6 -1.6 -2.7 1.6
Lung FVC 0.3 1.6 4.9 -0.0 -1.7 2.2 -0.5 -0.0 0.7 -0.0 -2.0 1.3
Neuroticism 0.6 1.5 3.2 -1.0 -1.8 0.2 0.5 -1.6 -1.1 -1.0 -1.8 1.0
Chronotype (morning person) 0.2 0.4 1.5 0.4 0.0 -0.3 -1.0 -0.7 0.0 0.4 0.7 1.2
Hair Pigment 0.0 1.2 3.5 -1.0 1.1 -1.4 0.2 -1.9 -1.5 -1.0 -0.4 0.4
Tanning 0.1 1.1 4.1 0.7 -0.8 2.0 0.1 0.6 0.1 0.7 0.4 -1.8
Hand grip strength (left) 0.1 0.4 0.8 0.2 0.9 0.6 0.8 0.6 0.6 0.2 -0.1 -0.7
Number of treatments/medications taken 1.3 2.4 5.7 2.1 1.0 -0.5 -2.4 0.6 2.2 2.1 0.5 -0.7
Average weekly spirits intake 1.5 1.9 5.1 1.7 0.5 1.0 -1.9 -1.1 2.2 1.7 0.3 -0.0
Sensitivity / hurt feelings 1.3 2.3 4.5 -1.6 -2.1 -0.2 1.1 -1.7 -1.7 -1.6 -1.5 1.2
Frequency of depressed mood in last 2 weeks 1.8 2.5 4.7 -2.2 -1.3 -1.2 0.6 -1.8 -1.5 -2.2 -1.4 1.3
Hearing difficulty/problems: Yes 0.1 0.2 0.7 -0.5 -0.8 -0.5 0.3 0.2 -0.1 -0.5 -0.2 -0.5
Relative age of first facial hair 0.5 1.0 2.8 -1.6 -0.2 0.7 0.3 -0.8 -1.7 -1.6 -0.2 0.3
Other serious medical condition/disability diagnosed by doctor 0.9 1.1 3.5 0.2 0.3 -0.7 -1.9 1.5 0.6 0.2 -0.9 -1.5
Ever used hormone-replacement therapy (HRT) 1.3 1.6 4.8 1.2 2.2 1.3 -1.5 -0.0 1.3 1.2 0.9 -0.2
Ever had hysterectomy (womb removed) 1.7 2.0 3.3 1.8 1.5 0.2 -1.7 0.6 1.6 1.8 0.9 1.5
Systolic blood pressure, automated reading 0.4 1.3 4.6 0.7 2.1 -1.8 -1.2 0.7 0.2 0.7 0.7 -0.5
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 1.1 -0.5 -0.3 0.4 0.6 -1.1 -0.9 -0.5 -0.0 0.9
Angina 1.7 2.3 4.8 2.0 2.2 0.6 -1.8 0.3 1.6 2.0 1.1 -0.1
Medication for hormone replacement therapy 0.6 0.7 1.1 0.9 1.0 -1.0 0.8 0.4 0.7 0.9 0.6 -0.7
Vitamin and mineral supplements 1.1 1.5 5.6 -0.9 0.1 -0.8 1.2 -2.4 -1.2 -0.9 -0.4 -1.4
Supplements: Zinc 0.8 0.9 2.0 -1.0 -1.0 -0.3 0.6 0.3 -0.8 -1.0 1.4 1.4
Medication: Co-codamol 0.7 0.8 3.6 -0.8 1.9 1.1 0.6 0.3 -0.0 -0.8 -0.8 0.1
Medication: Metformin 0.8 1.2 4.8 -0.3 0.8 -1.6 -2.2 -1.3 -0.2 -0.3 -0.5 -0.2
Diabetes (father) 0.9 1.1 3.0 -1.2 -0.8 -0.1 -0.3 0.3 -1.7 -1.2 0.3 -1.7
Diabetes (mother) 0.6 0.8 2.5 0.6 0.5 -0.3 -1.1 1.6 0.5 0.6 0.7 -1.2
Severe depression (siblings) 0.3 0.3 0.6 0.6 0.1 0.8 0.2 -0.6 0.3 0.6 0.7 -0.5
Pack years adult smoking proportion 0.1 0.1 0.7 0.1 0.8 -0.0 0.6 0.1 0.2 0.1 -0.2 -0.0
Impedance of leg (right) 0.4 2.1 7.2 -1.7 -1.4 -0.5 2.7 -0.3 -1.0 -1.7 -0.6 1.6
Leg fat-free mass (left) 0.2 0.9 3.2 1.0 1.1 -0.3 -1.8 -0.8 0.4 1.0 0.8 -0.5
Trunk fat percentage 1.0 4.0 13.4 2.2 2.0 -0.4 -3.7 -0.3 1.9 2.2 1.0 2.2
Hand grip strength (right) 0.2 0.5 1.1 -0.5 0.3 0.9 1.1 0.7 -0.6 -0.5 -0.1 -0.9
Townsend deprivation index at recruitment 0.2 0.3 1.0 0.1 1.0 -0.9 -0.4 -0.6 0.4 0.1 0.5 -0.1
Current tobacco smoking 0.5 0.8 6.6 -0.2 0.6 -0.0 -0.2 0.3 -0.4 -0.2 -0.4 2.6
Average weekly fortified wine intake 0.8 0.9 2.1 1.5 -0.2 -1.1 0.8 -0.0 1.5 1.5 -0.4 0.4
Maternal smoking around birth 0.2 0.3 1.0 -0.2 0.4 0.8 0.6 -1.0 0.3 -0.2 0.7 -0.2
Fed-up feelings 1.0 1.8 3.6 -1.9 -1.3 0.3 1.1 -0.9 -1.7 -1.9 -1.5 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.2 -0.3 -1.1 -0.4 -0.2 -0.5 0.1 -0.3 -0.7 1.0
Relative age voice broke 1.0 1.5 4.0 -1.6 0.6 -0.4 0.7 -1.8 -2.0 -1.6 0.1 -0.9
Taking other prescription medications 0.8 1.3 2.8 1.5 0.9 -0.2 -1.6 0.6 1.7 1.5 0.1 -0.0
Age when periods started (menarche) 0.1 0.3 0.8 -0.5 -0.9 -0.5 0.3 0.1 0.1 -0.5 0.3 0.8
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 1.6 -0.6 -0.2 -0.3 0.5 -0.1 -0.7 -0.6 -1.1 -1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 1.3 -0.5 -0.3 -0.5 1.1 0.4 -0.7 -0.5 -1.1 -1.1
Tinnitus: Yes, but not now, but have in the past 1.7 1.8 3.8 1.9 -0.5 1.2 -1.5 0.5 1.8 1.9 0.8 0.9
Qualifications: CSEs or equivalent 1.1 1.5 3.8 -0.8 0.0 -0.7 -0.5 -1.9 -0.9 -0.8 -1.9 1.8
Serious illness, injury or assault to yourself 0.7 0.8 3.4 -0.3 -1.1 1.2 0.8 1.8 0.1 -0.3 0.4 0.6
High blood pressure 2.0 5.5 11.6 3.2 2.1 -0.9 -3.2 0.7 3.4 3.2 0.5 1.3
Hayfever, allergic rhinitis or eczema 0.3 0.8 4.7 0.0 -0.4 0.1 2.2 1.3 -0.4 0.0 0.4 -0.1
Multivitamins +/- minerals 0.6 0.7 2.1 0.7 -0.0 -0.1 -0.7 1.2 0.7 0.7 -1.4 0.9
Stomach or abdominal pain in last month 0.8 1.0 2.3 -1.3 -0.8 1.1 0.6 -0.0 -1.5 -1.3 -0.9 0.2
Supplements: Glucosamine 1.0 1.3 2.4 0.8 1.1 1.2 1.5 0.9 1.5 0.8 -1.0 -1.1
Diverticular disease/diverticulitis (self-reported) 1.3 1.5 6.4 0.9 0.5 1.2 -2.5 0.5 1.5 0.9 -0.5 0.9
Medication: Atenolol 1.5 1.8 5.1 1.6 0.9 -0.2 -2.3 -0.2 1.7 1.6 -0.3 1.5
Medication: Levothyroxine sodium 2.2 3.8 13.8 2.1 2.3 0.0 -3.7 0.8 2.2 2.1 0.5 0.7
Sitting height 0.3 1.8 4.4 2.1 0.9 -0.9 -0.3 0.6 1.9 2.1 0.6 1.1
Chronic bronchitis/emphysema (father) 3.1 3.6 7.3 2.7 1.3 2.5 -0.5 -0.6 2.0 2.7 1.5 -1.8
High blood pressure (mother) 1.2 1.7 3.1 1.1 0.1 -1.8 -1.3 1.4 1.8 1.1 -0.6 1.6
Body mass index (BMI) 0.8 3.3 10.4 2.1 1.9 -0.1 -3.2 -0.4 1.6 2.1 1.4 1.4
Impedance of leg (left) 0.5 2.3 6.0 -2.0 -1.4 -0.2 2.4 0.3 -1.7 -2.0 -1.2 0.8
Leg predicted mass (left) 0.2 0.8 2.7 1.0 1.0 -0.3 -1.6 -0.8 0.4 1.0 0.8 -0.4
Trunk fat mass 0.8 3.6 11.7 2.2 2.0 -0.8 -3.4 -0.3 1.8 2.2 1.1 1.5
Waist circumference 0.8 3.0 10.1 1.9 2.1 -0.6 -3.2 -0.8 1.6 1.9 1.4 0.7
Number of incorrect matches in round 2.0 3.3 7.7 -2.6 -1.1 1.3 0.6 -0.8 -2.0 -2.6 -2.8 -0.8
Past tobacco smoking 0.9 1.7 3.8 -1.5 -0.6 -1.7 0.9 0.0 -1.0 -1.4 -1.4 1.9
Alcohol usually taken with meals 0.7 1.2 6.1 0.2 0.2 -0.8 -0.3 2.5 -0.6 0.2 1.8 -0.4
Nervous feelings 0.4 0.8 2.4 -0.4 -1.0 -0.3 0.9 -1.5 -0.5 -0.4 -1.5 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.1 -0.1 -1.0 0.5 0.5 -0.3 -0.0 -0.1 1.1 -0.1
Hearing difficulty/problems with background noise 0.2 0.3 0.9 0.5 -0.9 0.6 0.3 0.2 0.5 0.5 0.7 -0.5
Hair/balding pattern: Pattern 2 0.3 0.3 0.9 0.4 0.7 -0.6 -0.9 0.7 0.0 0.4 -0.6 0.4
Had menopause 0.2 0.3 0.9 0.3 0.9 1.0 -0.2 0.2 0.6 0.3 0.3 0.2
Had other major operations 0.7 0.9 2.3 0.3 1.0 1.2 0.8 1.4 0.3 0.3 1.5 0.1
Forced vital capacity (FVC) 0.2 0.7 2.7 -0.6 -1.7 -0.1 0.5 0.4 -0.4 -0.6 -1.4 -0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 3.7 -0.0 0.3 -1.2 1.0 0.7 -0.6 -0.0 -0.7 -1.9
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.4 -1.0 -0.6 0.6 0.5 0.2 -0.2 -1.0 0.1 -1.2
Qualifications: None of the above 0.3 0.5 1.4 -0.5 0.8 -0.6 -1.0 -1.2 -0.3 -0.5 -1.0 -0.2
Financial difficulties in last 2 years 1.2 1.6 3.7 -1.9 0.3 0.0 1.2 -1.6 -1.7 -1.9 -0.0 0.1
Mouth/teeth dental problems 0.3 0.5 2.0 0.3 -0.4 -0.0 0.4 0.5 -1.3 0.3 -1.4 0.5
Heart attack 0.4 0.5 1.8 -0.4 -0.2 -0.4 -1.2 0.7 0.1 -0.4 -0.3 1.3
Allergy 0.3 0.8 5.4 -0.4 0.2 -0.6 -2.3 -0.7 0.2 -0.4 -0.2 0.5
Pain all over the body in last month 0.4 0.5 2.1 -0.2 -0.3 1.3 0.0 1.4 0.0 -0.2 -0.1 0.4
Diabetes (self-reported) 0.5 0.7 2.4 -0.4 0.5 -1.5 -1.5 -0.7 -0.6 -0.4 -0.6 0.2
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.3 1.2 1.2 -0.8 0.1 -0.7 0.5 1.2 0.1 -1.5
Medication: Ramipril 0.8 1.0 2.9 1.1 -0.5 -0.1 -1.7 -1.1 1.4 1.1 0.1 0.6
Medication: Simvastatin 0.4 0.7 2.7 0.6 0.0 -0.4 -1.7 -0.8 0.2 0.6 -0.9 0.8
Fluid intelligence score 0.4 0.8 3.5 0.6 -0.6 -1.4 -0.2 -0.3 0.8 0.6 1.9 -0.5
Illnesses of siblings 1.1 1.5 4.5 -0.7 -2.1 0.3 1.8 1.4 -0.9 -0.7 1.2 -0.8
Neuroticism score 1.1 2.3 4.4 -1.7 -2.1 0.7 1.3 -1.6 -1.5 -1.7 -1.3 1.0
Weight 0.4 1.8 6.0 1.6 1.3 -0.7 -2.5 -0.4 1.1 1.6 1.1 0.4
Impedance of arm (right) 0.1 0.5 2.2 0.2 -1.2 0.2 0.4 0.8 0.4 0.2 0.3 1.5
Arm fat percentage (right) 1.2 4.9 12.4 2.7 2.0 -0.5 -3.5 -0.4 2.3 2.7 1.7 2.3
Trunk fat-free mass 0.1 0.5 3.0 -0.2 -0.0 -1.1 0.0 -0.5 -0.5 -0.2 -0.1 -1.7
Hip circumference 0.5 2.3 6.1 1.5 1.5 -1.2 -2.5 -0.8 1.1 1.5 2.0 0.8
Time employed in main current job 0.7 0.8 4.6 -0.4 -1.0 -0.7 2.1 0.3 -0.1 -0.4 0.6 -0.1
Alcohol intake versus 10 years previously 0.3 0.4 1.2 0.5 -0.7 0.3 -0.4 -1.1 0.4 0.5 -0.4 0.9
Father’s age at death 0.6 0.9 3.1 -0.6 -1.2 1.8 1.2 -0.5 -0.5 -0.6 -0.6 -0.6
Worrier / anxious feelings 0.2 0.4 1.1 1.0 0.1 0.3 0.5 -0.7 0.7 1.0 -0.2 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.3 0.9 0.5 0.6 -0.4 1.2 1.1 0.8 0.8 0.5
Falls in the last year 0.8 1.0 3.1 0.8 -0.4 0.9 -1.4 0.6 1.2 0.8 0.5 -1.8
Hair/balding pattern: Pattern 3 0.7 1.1 4.3 0.5 0.3 1.4 -1.1 -0.6 0.8 0.5 2.1 -1.0
Number of live births 0.6 0.9 1.5 0.6 -0.8 1.2 0.5 -0.7 1.2 0.6 -1.1 1.2
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 5.1 -0.8 -2.3 0.2 0.3 0.5 -0.6 -0.8 -1.5 -0.1
Pulse rate 0.5 0.8 3.5 -0.0 -1.2 -1.9 0.1 0.5 0.5 -0.0 1.3 0.4
Happiness 3.1 3.7 7.0 -2.2 -2.6 -2.0 1.1 -1.3 -2.6 -2.2 -1.4 0.8
Noisy workplace 0.7 0.9 3.0 1.0 -0.4 -1.2 -0.4 -0.0 0.5 1.1 0.8 1.7
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.9 0.3 0.2 -0.4 -0.1 0.7 0.9 0.3 0.1 -1.4
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 3.6 1.5 0.9 0.4 -1.9 -1.2 1.2 1.5 0.4 0.8
Mouth/teeth dental problems: Dentures 1.3 2.2 4.3 1.5 1.4 0.7 -1.8 -1.5 2.1 1.5 1.6 0.9
Asthma 0.3 0.5 2.9 -0.1 1.0 0.5 1.7 -0.2 -0.1 -0.1 -0.0 -0.5
Medication: Ibuprofen (e.g. Nurofen) 2.1 2.6 3.8 1.9 1.7 1.5 -1.9 1.6 1.7 1.9 1.0 -0.7
Medication: Cholesterol lowering 0.9 1.4 3.4 1.2 0.9 0.3 -1.9 -0.1 1.6 1.2 -1.5 0.7
Depression (self-reported) 1.1 1.3 3.9 -1.3 -2.0 -0.2 -0.1 -0.3 -1.2 -1.3 -1.5 0.7
Medication: Lansoprazole 0.4 0.4 1.0 -0.7 -0.9 -0.3 0.3 1.0 -0.1 -0.7 -0.9 0.5
Prospective memory result 1.1 1.4 4.9 -1.0 -1.5 -0.7 0.5 0.2 -0.5 -1.0 -1.6 2.2
Lung cancer (father) 1.1 1.2 2.8 -0.7 -1.0 1.3 1.1 -1.5 -0.2 -0.7 -1.7 1.0
Illnesses of mother 0.5 0.6 1.8 0.2 0.4 -0.0 1.3 1.1 -0.4 0.2 1.3 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 5.2 -1.9 -2.3 0.5 0.9 -0.6 -1.6 -1.9 -1.2 0.0
Pulse wave Arterial Stiffness index 0.5 0.6 4.7 -0.5 -2.2 0.2 -0.2 -0.5 0.1 -0.5 0.1 -0.1
Impedance of arm (left) 0.1 0.3 1.2 -0.4 -0.5 -0.0 0.7 0.3 -0.1 -0.4 -0.4 1.1
Arm fat mass (right) 0.8 3.2 9.0 2.1 1.7 -0.7 -3.0 -0.4 1.5 2.1 1.4 1.8
Trunk predicted mass 0.1 0.5 2.8 -0.1 -0.1 -1.2 -0.0 -0.5 -0.5 -0.1 -0.0 -1.7
Standing height 0.1 1.0 2.9 -0.6 -1.2 -0.8 1.5 0.2 -0.9 -0.6 -0.6 -1.7
Length of working week for main job 2.0 2.2 8.5 -0.9 -0.8 -0.2 2.1 2.9 -0.4 -0.9 0.7 2.0
Exposure to tobacco smoke at home 0.5 0.5 1.4 0.9 0.4 0.6 0.3 0.5 0.9 0.9 1.2 0.5
Breastfed as a baby 0.9 1.2 3.5 1.9 0.3 -0.2 -0.1 0.2 1.6 1.9 0.8 -0.2
Tense / ‘highly strung’ 0.8 1.3 4.7 -1.3 -2.2 0.3 0.5 -1.1 -0.8 -1.3 -1.4 -0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.3 -0.6 0.7 -0.3 -0.2 -0.1 -0.5 -0.6 -1.1 0.5
Hair/balding pattern: Pattern 4 0.1 0.2 0.3 0.6 -0.3 -0.5 0.4 0.0 0.5 0.6 -0.5 0.2
Birth weight of first child 0.3 0.6 2.2 -0.2 1.5 -0.8 0.1 0.9 -0.7 -0.2 0.8 -0.3
Peak expiratory flow (PEF) 0.7 1.7 4.2 2.1 0.4 1.3 -0.3 1.0 1.8 2.1 0.7 0.1
Pulse wave reflection index 0.8 0.9 2.0 -1.3 -1.4 0.6 0.5 -0.8 -0.6 -1.3 -1.1 -0.1
Ever highly irritable/argumentative for 2 days 2.4 2.9 16.3 -1.9 -4.0 0.0 0.8 0.9 -1.1 -1.9 0.1 -0.2
Loud music exposure frequency 0.3 0.3 0.9 -0.6 0.5 0.7 -1.0 0.3 -0.2 -0.6 -0.6 0.2
Qualifications: O levels/GCSEs or equivalent 0.7 1.0 5.8 -0.1 -1.1 0.8 1.1 -0.5 0.4 -0.1 0.5 -2.4
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 2.8 -1.7 -1.6 1.1 1.6 -0.4 -0.3 -1.7 -0.4 -0.9
Blood clot in the leg (DVT) 1.0 1.3 4.0 1.0 -0.9 1.6 -0.2 0.9 1.1 1.0 0.3 2.0
Medication: Paracetamol 0.5 0.8 2.2 0.4 1.1 -0.4 0.7 0.8 0.4 0.4 1.4 -1.5
Headache pain in last month 0.4 0.7 3.5 0.2 -1.9 -0.0 1.4 0.3 -0.0 0.1 0.9 0.3
Medication for cholesterol, blood pressure or diabetes 1.9 3.2 7.7 -2.4 -1.3 0.9 2.2 -0.7 -2.8 -2.4 0.3 -1.0
Glaucoma (self-reported) 1.7 2.0 6.6 1.3 0.5 -2.6 -1.4 1.9 0.8 1.3 0.4 1.2
Gout (self-reported) 1.6 2.2 4.2 2.0 2.0 -0.2 -1.5 -1.3 1.7 2.0 0.4 0.4
Hypothyroidism/myxoedema (self-reported) 3.0 5.9 24.4 2.9 2.1 0.2 -4.9 0.6 2.4 2.9 1.0 0.6
Medication: Amlodipine 0.6 0.8 1.9 0.9 0.8 -0.8 -1.2 0.1 1.0 0.9 0.2 1.4
Medication: Ventolin 100micrograms inhaler 1.0 1.3 2.6 -1.6 -0.6 -0.2 1.2 -0.3 -1.2 -1.6 -1.6 -0.8
Birth weight 0.4 1.0 2.4 1.0 1.0 1.5 -0.0 0.5 0.3 1.0 0.9 -1.5
Chronic bronchitis/emphysema (mother) 1.1 1.3 7.4 -0.1 0.4 1.4 -0.0 -2.7 0.3 -0.1 -1.1 0.6
High blood pressure (siblings) 1.0 1.4 2.6 1.2 1.6 -0.5 -0.7 -1.1 1.3 1.2 -1.3 1.2
Forced vital capacity (FVC), Best measure 0.5 1.7 4.9 -1.6 -2.2 0.4 1.2 -0.8 -1.3 -1.6 -1.1 -0.3
Body fat percentage 1.1 4.2 12.8 2.2 2.1 -0.8 -3.6 -0.3 1.9 2.2 1.1 2.3
Leg fat percentage (right) 0.9 3.3 6.7 1.6 2.0 -1.4 -2.6 -1.0 1.5 1.6 1.7 2.4
Arm fat-free mass (right) 0.1 0.3 1.0 -0.1 0.6 -1.0 -0.6 -0.9 -0.5 -0.1 -0.0 -0.5
Exposure to tobacco smoke outside home 1.0 1.3 3.5 0.7 0.2 1.9 -1.4 -0.2 1.5 0.7 0.1 -1.8
Comparative body size at age 10 0.3 0.8 4.3 0.4 -0.1 -0.4 -2.1 0.6 0.6 0.4 -0.4 -1.1
Number of full brothers 0.3 0.3 1.2 -0.5 0.2 -0.3 -0.3 -0.6 -1.1 -0.5 -0.7 -0.6
Worry too long after embarrassment 2.1 3.6 6.9 -2.5 -1.2 -0.6 1.6 -2.1 -2.6 -2.5 -2.0 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 4.6 -1.5 -0.6 0.9 0.9 -0.7 -0.9 -1.5 -2.1 -1.8
Wheeze or whistling in the chest in last year 0.6 1.0 3.4 0.3 0.9 -1.4 0.4 0.2 0.7 0.3 1.8 1.4
Number of children fathered 0.7 0.8 1.1 1.1 0.3 -0.7 -0.9 0.8 0.8 1.1 1.1 0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 0.9 -0.2 -0.3 -0.0 -0.8 -0.9 0.8 -0.2 -0.9 0.1
Age at first live birth 0.6 1.0 3.3 -0.4 -0.6 -1.8 1.5 0.9 -1.0 -0.4 0.2 -0.7
Pulse wave peak to peak time 0.4 0.5 3.2 0.3 1.8 -0.1 0.5 0.5 -0.3 0.3 -0.0 -0.2
Health satisfaction 0.8 1.0 3.5 -0.0 -0.3 -1.9 -0.1 0.8 0.4 -0.0 1.0 1.8
Shortness of breath walking on level ground 0.5 0.6 3.2 -0.1 -0.5 -1.8 0.3 0.3 -0.1 -0.1 -0.9 1.1
Qualifications: College or University degree 0.7 2.2 9.2 -0.0 -1.2 -3.0 1.2 1.1 0.7 -0.0 2.1 1.4
Eye problems/disorders: None of the above 1.4 1.7 5.6 -1.7 -2.4 1.1 0.9 0.3 -1.2 -1.7 -0.5 0.4
Mouth/teeth dental problems: Loose teeth 0.8 0.9 2.4 0.8 1.5 1.2 -0.3 -0.8 1.2 0.8 0.8 -0.0
Emphysema/chronic bronchitis 0.5 0.6 1.9 0.7 1.4 0.4 0.7 -1.0 0.3 0.7 -0.3 0.8
Medication for pain relief, constipation, heartburn 0.6 1.1 2.1 -1.0 -0.6 -0.5 0.7 -1.4 -1.2 -1.0 -1.1 1.5
Neck or shoulder pain in last month 1.0 1.5 4.7 1.4 0.9 0.1 0.2 1.6 0.9 1.4 2.2 -0.3
Medication: Blood pressure 1.3 2.3 4.6 1.7 1.3 -2.1 -1.5 0.7 2.1 1.7 -0.0 1.3
Angina (self-reported) 1.5 2.0 4.8 1.9 2.2 0.7 -1.5 0.1 1.4 1.9 1.2 -0.1
Migraine (self-reported) 1.4 1.7 7.3 1.1 0.5 1.5 0.2 1.2 1.0 1.1 2.7 0.9
Medication: Ibuprofen 2.4 2.9 4.1 2.0 1.7 1.5 -2.0 1.8 2.0 2.0 0.8 -1.1
Medication: Allopurinol 0.8 1.1 3.0 1.7 0.4 -0.1 -0.9 0.3 1.3 1.7 1.2 0.0
Medication: Omeprazole 0.9 1.1 2.7 -1.5 -0.8 1.0 -0.1 0.1 -1.0 -1.5 -1.6 0.1
Medication: Seretide 50 evohaler 0.7 0.8 2.3 -1.0 0.6 0.5 1.5 1.0 -0.7 -1.0 -0.6 -0.4
Mean time to correctly identify matches 0.9 1.8 4.3 -1.4 0.5 -1.3 0.8 -1.2 -2.1 -1.4 -1.1 1.7
Heart disease (mother) 3.2 3.8 9.1 3.0 0.7 1.2 -2.7 -0.4 2.6 3.0 0.0 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.5 0.8 0.4 0.7 -0.6 1.2 0.4 0.8 -0.3 0.8
Whole body fat mass 0.8 3.5 10.7 2.1 2.0 -0.9 -3.3 -0.5 1.6 2.1 1.0 1.9
Leg fat mass (right) 0.9 3.5 8.5 1.8 2.3 -0.9 -2.9 -1.0 1.4 1.8 1.6 2.1
Arm predicted mass (right) 0.1 0.4 1.0 -0.3 0.3 -1.0 -0.5 -1.0 -0.7 -0.3 -0.3 -0.8
Pulse rate, automated reading 1.5 4.8 10.2 -3.2 -0.9 -3.0 1.3 -1.1 -2.8 -3.2 -0.8 -1.0
Alcohol intake frequency. 0.5 1.1 3.5 1.4 0.1 0.2 -0.6 0.2 1.4 1.4 0.5 1.9
Comparative height size at age 10 0.2 1.1 5.6 0.4 -0.0 1.9 0.4 0.2 -0.0 0.4 0.2 -2.4
Number of full sisters 0.6 0.7 1.4 -0.9 -1.2 -0.6 0.5 -0.9 -0.9 -0.9 -1.1 -0.3
Suffer from ‘nerves’ 0.6 0.9 2.2 -1.0 -1.5 0.1 1.5 -0.8 -0.8 -1.0 -0.7 0.6
Overall health rating 0.2 0.4 1.3 -0.1 0.4 -0.9 -0.7 0.9 0.1 -0.1 -0.1 1.1
Chest pain or discomfort 0.4 0.6 3.0 0.8 -0.1 0.4 -0.4 0.7 0.8 0.8 0.1 1.7
Had major operations 2.1 2.5 5.1 1.9 -1.2 1.4 -2.0 -0.3 2.3 1.9 -1.1 -1.1
Age at last live birth 0.3 0.5 1.3 0.1 -0.8 -1.0 0.8 -0.2 0.6 0.1 -0.6 -1.1
Family relationship satisfaction 2.4 2.9 5.2 -2.3 -1.5 -1.8 0.8 -1.6 -1.8 -2.3 -2.0 0.4
Leg pain on walking 0.5 0.6 3.3 0.1 -0.5 -1.8 -1.0 0.5 -0.0 0.1 -0.0 0.7
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.5 6.1 0.9 -0.1 2.5 -1.5 1.3 0.5 0.9 0.5 -1.2
Commuting to job workplace: Car/motor vehicle 2.2 2.5 4.4 -2.1 -1.2 -0.1 1.9 0.8 -2.1 -2.1 1.6 1.4
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.4 -0.3 0.8 0.0 -0.1 1.2 -0.3 -0.3 -0.0 1.0
Medication: Aspirin 0.7 0.9 2.4 1.2 -0.4 -1.6 -0.2 0.6 1.1 1.2 1.0 0.1
Supplements: Vitamin C 1.4 1.7 6.4 -0.4 -0.9 0.7 0.1 2.5 0.0 -0.4 2.0 1.8
Knee pain experienced in last month 0.2 0.2 0.7 0.2 -0.1 0.8 -0.8 -0.1 0.5 0.2 -0.6 -0.4
Hypertension (Self-reported) 1.3 3.5 7.5 2.5 1.7 -1.2 -2.7 0.7 2.6 2.5 0.3 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 1.0 2.0 -1.4 -1.3 0.8 0.3 0.2 -0.8 -1.4 1.0 0.9
Illnesses of father: Heart disease 1.6 2.2 8.6 1.3 1.7 0.2 -2.9 -0.5 1.1 1.3 -0.5 1.7
Illnesses of siblings: Diabetes 0.9 1.1 4.2 0.4 1.3 0.7 -1.3 -2.0 0.8 0.4 -0.8 -0.8
Smoking status: Previous 1.0 1.5 6.9 0.9 0.3 1.4 -0.9 -0.6 0.6 0.9 1.2 -2.6
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 5.2 0.1 0.3 -0.2 -0.5 -2.2 -0.1 0.1 2.3 -1.1
Whole body fat-free mass 0.1 0.4 1.5 0.3 0.4 -0.8 -0.8 -0.6 -0.3 0.3 0.1 -1.2
Leg fat-free mass (right) 0.1 0.7 3.1 0.9 0.9 -0.0 -1.8 -0.3 0.1 0.9 0.4 -0.9
Arm fat percentage (left) 1.0 4.2 12.2 2.2 2.1 -0.8 -3.5 -0.7 1.9 2.2 1.3 2.2
Average weekly red wine intake 1.6 2.4 17.1 -0.5 0.2 -4.1 0.6 0.5 -0.9 -0.5 0.7 -1.2
Handedness (chirality/laterality): Left-handed 1.7 2.0 7.7 0.9 -2.0 -0.3 1.0 2.8 1.6 0.9 -0.0 -1.0
Mood swings 0.9 1.7 4.8 -1.4 -0.7 2.1 0.2 -0.5 -0.6 -1.4 -1.0 2.2
Loneliness, isolation 1.1 1.6 2.1 -1.4 -1.2 1.4 1.2 -1.3 -1.1 -1.4 0.4 1.4
Long-standing illness, disability or infirmity 0.8 1.2 3.3 1.0 0.2 0.1 -1.5 1.4 1.3 1.0 1.8 0.1
Ever had bowel cancer screening 0.4 0.5 1.8 -0.1 0.5 -0.9 -1.4 0.1 0.7 -0.1 -0.5 0.6
Diabetes diagnosed by doctor 0.7 1.1 2.7 -1.0 0.5 -1.2 -1.5 -1.6 -0.6 -1.0 -1.1 0.0
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 3.1 1.2 0.3 0.7 0.6 0.9 1.8 1.2 0.0 -0.4
Friendships satisfaction 0.9 1.1 2.1 -1.4 -1.3 -1.2 1.1 -0.0 -0.7 -1.4 -1.0 0.2
Qualifications: nursing, teaching 0.4 0.6 2.9 0.3 0.4 -0.2 1.7 1.4 0.3 0.3 -0.3 -0.4
Commuting to job workplace: Walk 1.3 1.4 3.4 1.5 1.9 0.9 -1.0 0.0 1.4 1.5 -0.8 0.2
Eye problems/disorders: Cataract 1.1 1.3 2.9 1.4 1.3 0.2 -0.8 -1.7 1.6 1.4 0.0 -0.0
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 2.8 -0.4 0.7 0.8 -0.6 1.6 0.7 -0.4 1.3 -1.7
Medication for cholesterol 2.2 3.4 10.1 -2.1 -1.1 0.8 3.2 -0.8 -2.7 -2.1 -1.1 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.1 2.9 1.5 0.2 1.7 -0.5 -0.2 1.4 1.5 0.1 -0.8
Back pain experienced in last month 0.2 0.2 0.7 0.8 0.6 0.6 0.0 -0.1 0.1 0.8 0.0 -0.0
Mineral and other dietary supplements 1.4 1.9 3.8 -1.4 -0.6 -1.9 0.7 -1.3 -1.6 -1.4 1.8 0.9
Breast cancer (self-reported) 0.8 0.9 2.2 -0.8 -0.1 0.8 0.5 1.4 -1.2 -0.8 -0.5 -1.5
Asthma (self-reported) 0.2 0.5 3.5 0.0 0.8 0.4 1.9 -0.1 0.1 0.0 0.1 -0.1
Osteoporosis (self-reported) 1.9 2.3 4.0 1.6 -0.3 -0.0 -2.0 2.0 1.3 1.6 -1.8 -1.7
Osteoarthritis (self-reported) 0.5 0.6 2.9 -0.9 -0.2 -0.1 -0.6 -0.7 -0.2 -0.9 -1.7 -0.1
Medication: Aspirin 0.7 1.0 2.8 1.4 -0.2 -1.7 -0.3 0.1 1.2 1.4 0.6 0.2
Medication: Gliclazide 1.7 1.9 6.4 -1.9 -0.3 -0.1 0.1 -2.5 -1.4 -1.9 -1.3 0.6
Illnesses of father: None of the above (group 1) 0.4 0.6 4.4 -0.1 -0.0 -0.4 2.1 0.4 0.2 -0.1 0.1 -0.3
Smoking status: Current 0.5 0.8 6.4 -0.2 0.3 0.1 -0.0 0.5 -0.5 -0.2 -0.5 2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.3 3.4 -1.5 -0.9 0.8 0.6 -1.2 -0.4 -1.5 -1.8 0.3
Whole body water mass 0.1 0.4 1.6 0.4 0.3 -0.8 -0.8 -0.5 -0.2 0.4 0.2 -1.3
Leg predicted mass (right) 0.1 0.7 2.9 0.9 0.9 -0.1 -1.7 -0.3 0.0 0.9 0.4 -0.9
Arm fat mass (left) 0.8 3.2 9.5 1.9 1.9 -1.0 -3.1 -0.8 1.4 1.9 1.3 1.8
Number of self-reported non-cancer illnesses 1.6 2.7 5.6 2.1 1.8 1.0 -2.2 0.3 2.4 2.1 0.4 -0.2
Average weekly champagne plus white wine intake 1.5 2.1 3.6 -1.9 -1.8 0.3 1.6 0.1 -1.2 -1.9 -1.1 -1.7
Miserableness 0.8 1.3 5.4 0.1 1.0 2.3 0.2 -0.2 0.0 0.1 -0.5 2.3
Guilty feelings 4.2 6.3 14.7 -3.8 -1.2 -1.6 1.4 -2.3 -3.6 -3.8 -1.7 -0.0
Wears glasses or contact lenses 0.6 0.6 1.6 0.7 1.3 -0.3 0.2 -1.0 0.9 0.7 0.2 -1.0
Ever taken oral contraceptive pill 3.7 4.1 25.3 1.8 0.3 5.0 -1.2 0.3 1.3 1.8 1.2 -0.3
Hearing aid user 0.3 0.3 1.1 -0.3 -0.1 -1.1 0.4 0.5 0.5 -0.3 0.9 -0.0
Mother’s age at death 0.3 0.3 0.8 0.3 -0.2 -0.8 0.9 0.7 0.9 0.3 0.1 0.2
Financial situation satisfaction 1.0 1.3 4.9 -1.5 -0.8 -2.2 0.1 0.1 -0.8 -1.5 -1.0 0.2
Tinnitus: Yes, now most or all of the time 0.1 0.2 0.4 -0.1 -0.4 0.1 -0.3 0.5 -0.7 -0.1 0.2 0.6
Commuting to job workplace: Public transport 1.4 1.6 4.3 1.8 1.2 -0.8 -0.4 0.8 2.1 1.8 0.4 -0.7
Eye problems/disorders: Glaucoma 1.8 2.2 6.2 1.5 1.0 -2.5 -1.7 0.7 1.5 1.5 0.2 1.5
Medication: Blood pressure 2.3 4.3 14.1 2.7 0.8 -0.2 -3.8 0.1 3.0 2.7 1.0 -0.0
Pain type(s) experienced in last month: Hip pain 0.8 1.1 3.0 0.8 -1.6 1.7 -1.0 0.4 0.4 0.8 1.2 -0.5
Supplements: Fish oil (including cod liver oil) 1.4 1.8 4.6 1.5 0.6 2.1 -0.3 1.1 1.9 1.5 -1.1 -0.8
High cholesterol (Self-reported) 1.1 2.0 7.8 1.5 0.7 0.7 -2.8 -0.0 2.0 1.5 -0.2 1.0
Medication: Bendroflumethiazide 2.2 3.3 10.6 1.7 2.1 -1.1 -3.3 0.6 2.6 1.7 0.3 0.8
Medication: Paracetamol 0.8 1.2 3.8 1.1 1.1 0.1 -0.6 0.8 0.8 1.1 1.2 -1.9
Medication: Lisinopril 1.1 1.4 4.6 1.3 0.6 -2.1 -0.9 1.3 1.4 1.3 0.1 0.0
Medication: Atorvastatin 0.9 1.1 5.1 1.1 0.5 0.5 -0.1 0.2 2.3 1.1 0.3 -1.2
Illnesses of father: High blood pressure 0.9 1.2 5.3 -0.8 1.0 -0.6 -1.6 -2.3 -0.5 -0.8 -0.3 0.1
Alcohol drinker status: Never 0.8 1.0 3.3 -0.6 -0.7 1.4 0.9 -1.8 0.0 -0.6 -0.9 0.8
Ever smoked 0.6 1.1 2.7 1.6 0.1 1.4 -0.8 0.1 0.9 1.6 0.8 -0.6
Basal metabolic rate 0.1 0.4 1.3 0.5 0.5 -0.8 -1.1 -0.5 -0.1 0.5 0.3 -0.8
Leg fat percentage (left) 0.8 2.8 8.5 1.3 2.0 -1.0 -2.9 -0.7 1.1 1.4 1.5 1.9
Arm fat-free mass (left) 0.0 0.2 0.5 0.4 0.3 -0.7 -0.5 0.0 -0.1 0.4 0.2 -0.6
Number of operations (self-reported) 1.4 2.1 8.2 1.9 0.5 2.9 -0.5 0.5 1.8 1.9 0.0 -0.2
Average weekly beer plus cider intake 0.5 0.7 2.7 0.9 1.0 1.6 0.9 -0.3 0.0 0.9 -0.6 -0.5
Irritability 0.9 1.6 5.4 -1.0 -2.3 1.9 0.1 0.6 -0.6 -1.0 0.5 1.5
Risk taking 1.4 2.0 7.0 0.1 0.1 2.4 0.4 -0.2 0.2 0.1 2.2 -2.6
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.6 0.8 0.3 -0.5 -0.9 0.6 1.6 0.8 -1.4 0.6
Fractured/broken bones in last 5 years 1.1 1.5 4.8 1.1 1.3 0.2 -1.8 0.7 0.6 1.1 2.2 -0.2
Age started oral contraceptive pill 0.2 0.2 0.7 -0.3 -0.4 -0.6 0.9 0.3 -0.0 -0.3 0.4 0.7
Diastolic blood pressure, automated reading 0.5 1.6 7.3 0.4 1.1 -2.7 -1.1 0.4 -0.3 0.4 1.3 -1.5
Ever depressed for a whole week 0.9 1.1 2.9 -1.4 -1.7 -0.2 1.4 0.1 -0.8 -1.4 -0.1 -0.9
Unable to work because of sickness or disability 0.2 0.3 1.2 0.5 -0.3 -0.4 -0.6 1.1 0.1 0.5 0.7 0.3
Commuting to job workplace: Cycle 4.7 5.6 15.5 3.4 1.9 -1.0 -1.1 1.7 3.9 3.4 1.7 0.7
Myopia 1.1 1.6 4.3 -1.5 -0.6 -0.5 0.0 1.0 -1.9 -1.5 -2.1 -0.6
Vascular/heart problems diagnosed by doctor 2.0 5.4 10.7 -3.2 -1.4 0.9 3.3 -0.8 -3.3 -3.2 -1.2 -1.5
Cholesterol lowering medication 0.9 1.3 4.8 1.1 -0.0 0.1 -2.2 -0.2 1.6 1.1 1.4 0.3
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 2.5 -1.2 -1.1 1.1 0.1 0.4 -0.8 -1.2 -1.6 -0.5
Pain experienced in last month 0.4 0.6 2.2 -0.7 0.4 -1.5 -0.9 -0.6 -0.1 -0.7 -0.6 0.8
Supplements: Calcium 1.8 1.9 7.0 1.4 -0.4 0.2 -2.6 -0.5 1.7 1.4 0.5 1.7
Basal cell carcinoma (self-reported) 0.7 0.9 6.1 0.5 0.1 -0.8 -0.6 0.4 0.6 0.5 -0.1 -2.5
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.8 -0.3 0.0 -0.2 -1.1 0.9 0.2 -0.2 -0.1 1.3
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 3.2 1.1 -0.5 1.4 -0.3 1.2 1.2 1.1 0.4 1.8
Heart disease (siblings) 1.2 1.5 3.7 0.3 0.9 1.7 -1.9 -1.6 0.6 0.3 -0.6 1.6
Alcohol drinker status: Previous 1.1 1.3 2.8 1.2 0.4 1.1 -0.7 1.2 1.7 1.2 1.5 -0.3
Pack years of smoking 0.0 0.1 0.3 -0.2 0.3 -0.0 0.5 0.1 -0.1 -0.2 -0.3 -0.3
Impedance of whole body 0.2 0.9 2.4 -1.0 -1.0 -0.1 1.6 0.7 -0.7 -1.0 -0.5 1.3
Leg fat mass (left) 0.8 3.2 9.4 1.7 2.4 -0.7 -3.1 -1.0 1.2 1.7 1.4 1.8
Arm predicted mass (left) 0.0 0.1 0.5 0.3 0.2 -0.6 -0.4 -0.1 -0.2 0.3 0.1 -0.7