Hub : Genes

MB21D2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1100	0.0370	4.4e-04	0.110	NA	0.087	NA	0.107	3.0e-09	NA	1.5e-07	NA	5.0e-09
2	GTEx	Adipose Visceral Omentum	0.1310	0.0510	5.7e-03	0.014	NA	0.083	NA	0.033	5.9e-02	NA	4.3e-05	NA	8.0e-03
3	GTEx	Adrenal Gland	0.2792	0.0706	1.8e-05	0.310	NA	0.286	NA	0.341	9.1e-12	NA	8.3e-11	NA	5.5e-13
4	GTEx	Cells EBV-transformed lymphocytes	0.7330	0.0670	1.6e-11	0.556	NA	0.591	NA	0.629	1.6e-21	NA	1.6e-23	NA	7.0e-26
5	GTEx	Cells Transformed fibroblasts	0.2860	0.0570	2.0e-07	0.210	NA	0.204	NA	0.214	1.1e-15	NA	3.0e-15	NA	5.1e-16
6	GTEx	Esophagus Mucosa	0.1420	0.0480	1.5e-03	0.034	NA	0.022	NA	0.027	2.4e-03	NA	1.3e-02	NA	6.3e-03
7	GTEx	Lung	0.0779	0.0314	6.9e-03	0.074	NA	0.016	NA	0.053	2.5e-06	NA	2.1e-02	NA	6.4e-05
8	GTEx	Thyroid	0.1060	0.0410	5.3e-03	0.001	NA	0.000	NA	0.001	2.7e-01	NA	3.0e-01	NA	2.4e-01
9	METSIM	Adipose	0.0519	0.0242	1.4e-02	0.036	0.011	0.028	0.022	0.030	4.1e-06	0.0064	3.9e-05	0.00028	2.1e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.8	1.2	2.8	1.7	0.5	0.6	0.2	1.4	1.7	1.7	0.1	-0.5
Bipolar Disorder or Schizophrenia	0.4	0.9	2.4	0.8	1.3	0.0	0.2	1.3	1.1	0.8	1.5	-0.3
Depressed Affect (Nagel 2018)	0.7	1.4	5.6	-0.2	-0.4	2.4	-0.3	-1.0	0.2	-0.2	-0.8	2.2
Depression (Nagel 2018)	1.3	2.0	3.5	-1.6	-1.9	-1.2	0.3	-1.4	-1.2	-1.6	-1.6	1.3
Intelligence (Savage-Jansen 2018)	1.6	4.8	9.5	2.7	0.6	-1.8	-2.4	0.2	2.8	2.7	3.1	-1.5
Neuroticism (Nagel 2018)	0.8	2.0	4.6	-1.6	-1.7	0.8	0.2	-1.2	-1.1	-1.6	-2.2	1.4
Schizophrenia (2018)	0.3	0.7	3.9	-0.3	1.3	-0.5	0.0	0.6	0.1	-0.3	2.0	0.1
Schizophrenia vs Biploar Disorder	2.2	2.8	7.2	-2.7	-0.3	-1.6	1.1	-0.3	-2.6	-2.7	0.4	0.3
Worry (Nagel 2018)	0.5	1.0	3.3	-0.5	-1.5	-0.1	0.6	-1.4	-0.4	-0.5	-1.8	0.6
Alzheimer’s Disease (in mother)	1.6	1.8	3.7	-1.9	1.2	-0.2	-0.3	-1.8	-1.7	-1.9	-1.0	-0.8
Alzheimer’s Disease (in father)	0.6	0.6	2.4	-0.2	1.3	-0.9	-0.6	-0.6	-0.2	-0.2	0.2	1.6
Alzheimer’s Disease (including proxy)	0.8	1.1	3.0	-1.2	1.2	-0.3	-1.0	-1.7	-1.2	-1.2	-0.4	-0.4
Crohns Disease (2017)	1.3	2.8	5.8	2.0	1.8	0.1	-2.4	-0.5	1.1	2.0	2.1	-1.5
Irritable Bowel Disease (IBD)	1.5	3.6	9.1	2.4	1.4	1.1	-3.0	-1.1	1.4	2.4	1.8	-1.5
Ulcerative Colitis (UC)	0.7	1.3	3.5	1.5	0.3	1.2	-1.9	-0.2	0.9	1.5	0.8	-0.7
Major Depression (MDD)	0.1	0.2	0.7	0.2	-0.4	0.3	-0.3	-0.8	0.4	0.2	-0.4	0.5
Reaction Time	1.7	3.2	8.1	-1.7	-0.4	-2.1	1.6	-0.4	-2.8	-1.7	-0.9	2.5
Verbal and Numeric Reasoning (VNR)	1.9	4.6	9.2	3.0	0.5	-0.8	-2.5	0.7	2.9	3.0	2.7	-0.3
Breast Cancer	1.5	3.6	11.0	2.4	0.6	3.3	-1.5	1.0	2.2	2.4	1.0	0.7
Ovarian Cancer	0.3	0.3	1.2	0.0	0.8	1.1	0.3	-0.9	0.3	0.0	-0.4	-0.4
Prostate Cancer	0.4	0.5	2.8	-0.4	-0.0	-0.3	1.7	1.0	-0.6	-0.4	0.1	-0.5
Age at First Birth	0.4	0.5	3.0	-0.1	-0.4	-0.6	1.7	0.6	-0.7	-0.1	0.3	0.4
Bipolar Disorder (2011)	1.5	1.5	4.7	1.8	-0.4	0.6	-0.4	0.6	2.2	1.8	1.0	0.0
Body Mass Index (BMI) (2010)	1.2	1.6	3.5	1.6	1.5	-1.2	-0.9	0.5	1.9	1.6	1.0	0.5
Coronary Artery Disease (CAD)	0.7	0.8	2.4	0.4	1.3	1.0	-1.2	0.6	0.2	0.4	1.6	0.1
Crohns Disease (2012)	1.3	2.1	4.6	2.0	0.3	-0.6	-2.1	0.2	1.3	2.0	1.4	-1.5
Mean Putamen Volume	0.4	0.5	1.6	-0.4	-0.6	1.3	-0.1	-1.1	-0.1	-0.4	1.0	0.4
Fasting Glucose	0.2	0.2	0.7	-0.2	0.6	-0.7	-0.2	0.1	-0.0	-0.2	0.8	0.6
HbA1C	0.4	0.4	0.9	0.9	0.2	-0.9	0.1	-0.0	0.2	0.9	0.7	-0.6
HDL Cholesterol	0.7	1.1	5.1	-0.8	-1.3	0.8	2.3	0.0	-1.0	-0.8	-0.1	0.4
LDL Cholesterol	0.2	0.3	0.7	-0.7	0.0	0.2	0.4	0.5	-0.8	-0.7	-0.5	-0.0
Lupus	0.3	0.4	0.8	0.8	0.6	-0.3	0.0	-0.8	0.8	0.8	0.9	0.0
Neuroticism (2016)	0.5	0.7	2.3	-0.4	-1.5	0.8	0.4	-0.2	-0.9	-0.4	-1.3	-0.9
Primary Biliary Cirrhosis	1.0	1.4	5.8	-0.6	0.1	-1.8	-1.4	-2.4	-0.7	-0.6	-0.0	0.7
Rheumatoid Arthritis	3.6	5.0	12.5	2.5	2.6	0.8	-3.5	-2.0	2.1	2.5	1.9	1.1
Schizophrenia (2014)	0.3	0.6	2.8	-0.4	0.8	-1.2	-0.3	0.4	-0.2	-0.4	1.7	-0.2
Triglycerides	0.4	0.7	3.2	-0.2	0.7	-0.1	-1.8	-0.5	-0.2	-0.2	-1.3	-0.2
Type 2 Diabetes (T2D) (2012)	1.6	1.8	5.3	1.7	1.9	-0.4	0.1	-0.9	0.7	1.7	0.5	-2.3
Ulcerative Colitis	0.5	0.7	2.0	1.0	-0.1	0.3	-1.3	-0.3	0.6	1.1	1.4	-0.0
Blood Eosinophil Count	0.2	1.4	3.2	0.2	0.0	-1.6	1.8	0.2	-0.8	0.2	-1.8	-1.6
Blood Platelet Count	0.1	1.2	2.9	-1.7	0.1	0.2	0.1	-1.4	-0.9	-1.7	-0.7	-1.1
Blood Red Count	0.3	2.4	4.8	2.2	-0.4	-1.2	-0.8	2.2	1.8	2.2	1.6	-0.2
Blood White Count	0.1	0.8	2.8	0.1	0.5	-1.7	0.3	-1.0	-0.4	0.1	-0.0	1.6
Heel T-Score	0.1	0.5	2.4	-0.1	0.0	-0.9	1.6	-0.1	-0.4	-0.1	-0.4	-0.9
BMI	0.5	3.0	5.6	1.9	1.4	-0.0	-2.1	0.3	1.9	1.9	2.1	2.4
Height	0.1	1.9	6.0	-1.3	-0.1	-2.4	1.6	0.4	-0.8	-1.3	-1.1	-1.9
Waist Hip Ratio (WHR)	0.1	0.6	3.9	-0.0	0.8	0.3	-0.7	-0.6	-0.0	-0.1	-0.6	-2.0
Systolic Blood Pressure	0.3	1.5	4.5	1.0	1.3	-2.1	-1.5	0.5	0.3	1.0	1.1	-1.1
Smoking Status	0.3	0.7	1.6	0.8	0.6	1.2	-0.9	-0.5	0.7	0.8	-1.0	0.4
Allergy or Eczema	0.4	1.1	3.8	0.6	0.7	1.2	2.0	1.5	0.0	0.6	0.6	-0.7
Cardiovascular Disease	0.6	2.1	4.4	2.0	0.3	-0.5	-2.1	0.2	2.1	2.0	0.2	1.5
Hypothyroidism (self reported)	3.4	7.8	29.5	3.3	2.9	0.2	-5.4	-0.2	2.7	3.3	1.4	0.9
Respiratory disease	0.7	1.6	11.2	-0.8	0.6	-0.5	3.3	-0.1	-1.2	-0.8	0.0	0.1
Type 2 Diabetes (T2D) (2018)	0.5	1.0	3.8	-1.0	0.5	-2.0	-0.5	-1.2	-0.7	-1.0	0.4	-0.5
Lung FEV1/FVC ratio	0.6	2.9	7.2	-1.6	-1.8	1.9	0.6	-1.4	-1.6	-1.6	-2.7	1.6
Lung FVC	0.3	1.6	4.9	-0.0	-1.7	2.2	-0.5	-0.0	0.7	-0.0	-2.0	1.3
Neuroticism	0.6	1.5	3.2	-1.0	-1.8	0.2	0.5	-1.6	-1.1	-1.0	-1.8	1.0
Chronotype (morning person)	0.2	0.4	1.5	0.4	0.0	-0.3	-1.0	-0.7	0.0	0.4	0.7	1.2
Hair Pigment	0.0	1.2	3.5	-1.0	1.1	-1.4	0.2	-1.9	-1.5	-1.0	-0.4	0.4
Tanning	0.1	1.1	4.1	0.7	-0.8	2.0	0.1	0.6	0.1	0.7	0.4	-1.8
Hand grip strength (left)	0.1	0.4	0.8	0.2	0.9	0.6	0.8	0.6	0.6	0.2	-0.1	-0.7
Number of treatments/medications taken	1.3	2.4	5.7	2.1	1.0	-0.5	-2.4	0.6	2.2	2.1	0.5	-0.7
Average weekly spirits intake	1.5	1.9	5.1	1.7	0.5	1.0	-1.9	-1.1	2.2	1.7	0.3	-0.0
Sensitivity / hurt feelings	1.3	2.3	4.5	-1.6	-2.1	-0.2	1.1	-1.7	-1.7	-1.6	-1.5	1.2
Frequency of depressed mood in last 2 weeks	1.8	2.5	4.7	-2.2	-1.3	-1.2	0.6	-1.8	-1.5	-2.2	-1.4	1.3
Hearing difficulty/problems: Yes	0.1	0.2	0.7	-0.5	-0.8	-0.5	0.3	0.2	-0.1	-0.5	-0.2	-0.5
Relative age of first facial hair	0.5	1.0	2.8	-1.6	-0.2	0.7	0.3	-0.8	-1.7	-1.6	-0.2	0.3
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	3.5	0.2	0.3	-0.7	-1.9	1.5	0.6	0.2	-0.9	-1.5
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.8	1.2	2.2	1.3	-1.5	-0.0	1.3	1.2	0.9	-0.2
Ever had hysterectomy (womb removed)	1.7	2.0	3.3	1.8	1.5	0.2	-1.7	0.6	1.6	1.8	0.9	1.5
Systolic blood pressure, automated reading	0.4	1.3	4.6	0.7	2.1	-1.8	-1.2	0.7	0.2	0.7	0.7	-0.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.1	-0.5	-0.3	0.4	0.6	-1.1	-0.9	-0.5	-0.0	0.9
Angina	1.7	2.3	4.8	2.0	2.2	0.6	-1.8	0.3	1.6	2.0	1.1	-0.1
Medication for hormone replacement therapy	0.6	0.7	1.1	0.9	1.0	-1.0	0.8	0.4	0.7	0.9	0.6	-0.7
Vitamin and mineral supplements	1.1	1.5	5.6	-0.9	0.1	-0.8	1.2	-2.4	-1.2	-0.9	-0.4	-1.4
Supplements: Zinc	0.8	0.9	2.0	-1.0	-1.0	-0.3	0.6	0.3	-0.8	-1.0	1.4	1.4
Medication: Co-codamol	0.7	0.8	3.6	-0.8	1.9	1.1	0.6	0.3	-0.0	-0.8	-0.8	0.1
Medication: Metformin	0.8	1.2	4.8	-0.3	0.8	-1.6	-2.2	-1.3	-0.2	-0.3	-0.5	-0.2
Diabetes (father)	0.9	1.1	3.0	-1.2	-0.8	-0.1	-0.3	0.3	-1.7	-1.2	0.3	-1.7
Diabetes (mother)	0.6	0.8	2.5	0.6	0.5	-0.3	-1.1	1.6	0.5	0.6	0.7	-1.2
Severe depression (siblings)	0.3	0.3	0.6	0.6	0.1	0.8	0.2	-0.6	0.3	0.6	0.7	-0.5
Pack years adult smoking proportion	0.1	0.1	0.7	0.1	0.8	-0.0	0.6	0.1	0.2	0.1	-0.2	-0.0
Impedance of leg (right)	0.4	2.1	7.2	-1.7	-1.4	-0.5	2.7	-0.3	-1.0	-1.7	-0.6	1.6
Leg fat-free mass (left)	0.2	0.9	3.2	1.0	1.1	-0.3	-1.8	-0.8	0.4	1.0	0.8	-0.5
Trunk fat percentage	1.0	4.0	13.4	2.2	2.0	-0.4	-3.7	-0.3	1.9	2.2	1.0	2.2
Hand grip strength (right)	0.2	0.5	1.1	-0.5	0.3	0.9	1.1	0.7	-0.6	-0.5	-0.1	-0.9
Townsend deprivation index at recruitment	0.2	0.3	1.0	0.1	1.0	-0.9	-0.4	-0.6	0.4	0.1	0.5	-0.1
Current tobacco smoking	0.5	0.8	6.6	-0.2	0.6	-0.0	-0.2	0.3	-0.4	-0.2	-0.4	2.6
Average weekly fortified wine intake	0.8	0.9	2.1	1.5	-0.2	-1.1	0.8	-0.0	1.5	1.5	-0.4	0.4
Maternal smoking around birth	0.2	0.3	1.0	-0.2	0.4	0.8	0.6	-1.0	0.3	-0.2	0.7	-0.2
Fed-up feelings	1.0	1.8	3.6	-1.9	-1.3	0.3	1.1	-0.9	-1.7	-1.9	-1.5	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.2	-0.3	-1.1	-0.4	-0.2	-0.5	0.1	-0.3	-0.7	1.0
Relative age voice broke	1.0	1.5	4.0	-1.6	0.6	-0.4	0.7	-1.8	-2.0	-1.6	0.1	-0.9
Taking other prescription medications	0.8	1.3	2.8	1.5	0.9	-0.2	-1.6	0.6	1.7	1.5	0.1	-0.0
Age when periods started (menarche)	0.1	0.3	0.8	-0.5	-0.9	-0.5	0.3	0.1	0.1	-0.5	0.3	0.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.6	-0.6	-0.2	-0.3	0.5	-0.1	-0.7	-0.6	-1.1	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.3	-0.5	-0.3	-0.5	1.1	0.4	-0.7	-0.5	-1.1	-1.1
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	3.8	1.9	-0.5	1.2	-1.5	0.5	1.8	1.9	0.8	0.9
Qualifications: CSEs or equivalent	1.1	1.5	3.8	-0.8	0.0	-0.7	-0.5	-1.9	-0.9	-0.8	-1.9	1.8
Serious illness, injury or assault to yourself	0.7	0.8	3.4	-0.3	-1.1	1.2	0.8	1.8	0.1	-0.3	0.4	0.6
High blood pressure	2.0	5.5	11.6	3.2	2.1	-0.9	-3.2	0.7	3.4	3.2	0.5	1.3
Hayfever, allergic rhinitis or eczema	0.3	0.8	4.7	0.0	-0.4	0.1	2.2	1.3	-0.4	0.0	0.4	-0.1
Multivitamins +/- minerals	0.6	0.7	2.1	0.7	-0.0	-0.1	-0.7	1.2	0.7	0.7	-1.4	0.9
Stomach or abdominal pain in last month	0.8	1.0	2.3	-1.3	-0.8	1.1	0.6	-0.0	-1.5	-1.3	-0.9	0.2
Supplements: Glucosamine	1.0	1.3	2.4	0.8	1.1	1.2	1.5	0.9	1.5	0.8	-1.0	-1.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	6.4	0.9	0.5	1.2	-2.5	0.5	1.5	0.9	-0.5	0.9
Medication: Atenolol	1.5	1.8	5.1	1.6	0.9	-0.2	-2.3	-0.2	1.7	1.6	-0.3	1.5
Medication: Levothyroxine sodium	2.2	3.8	13.8	2.1	2.3	0.0	-3.7	0.8	2.2	2.1	0.5	0.7
Sitting height	0.3	1.8	4.4	2.1	0.9	-0.9	-0.3	0.6	1.9	2.1	0.6	1.1
Chronic bronchitis/emphysema (father)	3.1	3.6	7.3	2.7	1.3	2.5	-0.5	-0.6	2.0	2.7	1.5	-1.8
High blood pressure (mother)	1.2	1.7	3.1	1.1	0.1	-1.8	-1.3	1.4	1.8	1.1	-0.6	1.6
Body mass index (BMI)	0.8	3.3	10.4	2.1	1.9	-0.1	-3.2	-0.4	1.6	2.1	1.4	1.4
Impedance of leg (left)	0.5	2.3	6.0	-2.0	-1.4	-0.2	2.4	0.3	-1.7	-2.0	-1.2	0.8
Leg predicted mass (left)	0.2	0.8	2.7	1.0	1.0	-0.3	-1.6	-0.8	0.4	1.0	0.8	-0.4
Trunk fat mass	0.8	3.6	11.7	2.2	2.0	-0.8	-3.4	-0.3	1.8	2.2	1.1	1.5
Waist circumference	0.8	3.0	10.1	1.9	2.1	-0.6	-3.2	-0.8	1.6	1.9	1.4	0.7
Number of incorrect matches in round	2.0	3.3	7.7	-2.6	-1.1	1.3	0.6	-0.8	-2.0	-2.6	-2.8	-0.8
Past tobacco smoking	0.9	1.7	3.8	-1.5	-0.6	-1.7	0.9	0.0	-1.0	-1.4	-1.4	1.9
Alcohol usually taken with meals	0.7	1.2	6.1	0.2	0.2	-0.8	-0.3	2.5	-0.6	0.2	1.8	-0.4
Nervous feelings	0.4	0.8	2.4	-0.4	-1.0	-0.3	0.9	-1.5	-0.5	-0.4	-1.5	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-0.1	-1.0	0.5	0.5	-0.3	-0.0	-0.1	1.1	-0.1
Hearing difficulty/problems with background noise	0.2	0.3	0.9	0.5	-0.9	0.6	0.3	0.2	0.5	0.5	0.7	-0.5
Hair/balding pattern: Pattern 2	0.3	0.3	0.9	0.4	0.7	-0.6	-0.9	0.7	0.0	0.4	-0.6	0.4
Had menopause	0.2	0.3	0.9	0.3	0.9	1.0	-0.2	0.2	0.6	0.3	0.3	0.2
Had other major operations	0.7	0.9	2.3	0.3	1.0	1.2	0.8	1.4	0.3	0.3	1.5	0.1
Forced vital capacity (FVC)	0.2	0.7	2.7	-0.6	-1.7	-0.1	0.5	0.4	-0.4	-0.6	-1.4	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.7	-0.0	0.3	-1.2	1.0	0.7	-0.6	-0.0	-0.7	-1.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.4	-1.0	-0.6	0.6	0.5	0.2	-0.2	-1.0	0.1	-1.2
Qualifications: None of the above	0.3	0.5	1.4	-0.5	0.8	-0.6	-1.0	-1.2	-0.3	-0.5	-1.0	-0.2
Financial difficulties in last 2 years	1.2	1.6	3.7	-1.9	0.3	0.0	1.2	-1.6	-1.7	-1.9	-0.0	0.1
Mouth/teeth dental problems	0.3	0.5	2.0	0.3	-0.4	-0.0	0.4	0.5	-1.3	0.3	-1.4	0.5
Heart attack	0.4	0.5	1.8	-0.4	-0.2	-0.4	-1.2	0.7	0.1	-0.4	-0.3	1.3
Allergy	0.3	0.8	5.4	-0.4	0.2	-0.6	-2.3	-0.7	0.2	-0.4	-0.2	0.5
Pain all over the body in last month	0.4	0.5	2.1	-0.2	-0.3	1.3	0.0	1.4	0.0	-0.2	-0.1	0.4
Diabetes (self-reported)	0.5	0.7	2.4	-0.4	0.5	-1.5	-1.5	-0.7	-0.6	-0.4	-0.6	0.2
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.3	1.2	1.2	-0.8	0.1	-0.7	0.5	1.2	0.1	-1.5
Medication: Ramipril	0.8	1.0	2.9	1.1	-0.5	-0.1	-1.7	-1.1	1.4	1.1	0.1	0.6
Medication: Simvastatin	0.4	0.7	2.7	0.6	0.0	-0.4	-1.7	-0.8	0.2	0.6	-0.9	0.8
Fluid intelligence score	0.4	0.8	3.5	0.6	-0.6	-1.4	-0.2	-0.3	0.8	0.6	1.9	-0.5
Illnesses of siblings	1.1	1.5	4.5	-0.7	-2.1	0.3	1.8	1.4	-0.9	-0.7	1.2	-0.8
Neuroticism score	1.1	2.3	4.4	-1.7	-2.1	0.7	1.3	-1.6	-1.5	-1.7	-1.3	1.0
Weight	0.4	1.8	6.0	1.6	1.3	-0.7	-2.5	-0.4	1.1	1.6	1.1	0.4
Impedance of arm (right)	0.1	0.5	2.2	0.2	-1.2	0.2	0.4	0.8	0.4	0.2	0.3	1.5
Arm fat percentage (right)	1.2	4.9	12.4	2.7	2.0	-0.5	-3.5	-0.4	2.3	2.7	1.7	2.3
Trunk fat-free mass	0.1	0.5	3.0	-0.2	-0.0	-1.1	0.0	-0.5	-0.5	-0.2	-0.1	-1.7
Hip circumference	0.5	2.3	6.1	1.5	1.5	-1.2	-2.5	-0.8	1.1	1.5	2.0	0.8
Time employed in main current job	0.7	0.8	4.6	-0.4	-1.0	-0.7	2.1	0.3	-0.1	-0.4	0.6	-0.1
Alcohol intake versus 10 years previously	0.3	0.4	1.2	0.5	-0.7	0.3	-0.4	-1.1	0.4	0.5	-0.4	0.9
Father’s age at death	0.6	0.9	3.1	-0.6	-1.2	1.8	1.2	-0.5	-0.5	-0.6	-0.6	-0.6
Worrier / anxious feelings	0.2	0.4	1.1	1.0	0.1	0.3	0.5	-0.7	0.7	1.0	-0.2	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.3	0.9	0.5	0.6	-0.4	1.2	1.1	0.8	0.8	0.5
Falls in the last year	0.8	1.0	3.1	0.8	-0.4	0.9	-1.4	0.6	1.2	0.8	0.5	-1.8
Hair/balding pattern: Pattern 3	0.7	1.1	4.3	0.5	0.3	1.4	-1.1	-0.6	0.8	0.5	2.1	-1.0
Number of live births	0.6	0.9	1.5	0.6	-0.8	1.2	0.5	-0.7	1.2	0.6	-1.1	1.2
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	5.1	-0.8	-2.3	0.2	0.3	0.5	-0.6	-0.8	-1.5	-0.1
Pulse rate	0.5	0.8	3.5	-0.0	-1.2	-1.9	0.1	0.5	0.5	-0.0	1.3	0.4
Happiness	3.1	3.7	7.0	-2.2	-2.6	-2.0	1.1	-1.3	-2.6	-2.2	-1.4	0.8
Noisy workplace	0.7	0.9	3.0	1.0	-0.4	-1.2	-0.4	-0.0	0.5	1.1	0.8	1.7
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.9	0.3	0.2	-0.4	-0.1	0.7	0.9	0.3	0.1	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.6	1.5	0.9	0.4	-1.9	-1.2	1.2	1.5	0.4	0.8
Mouth/teeth dental problems: Dentures	1.3	2.2	4.3	1.5	1.4	0.7	-1.8	-1.5	2.1	1.5	1.6	0.9
Asthma	0.3	0.5	2.9	-0.1	1.0	0.5	1.7	-0.2	-0.1	-0.1	-0.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.6	3.8	1.9	1.7	1.5	-1.9	1.6	1.7	1.9	1.0	-0.7
Medication: Cholesterol lowering	0.9	1.4	3.4	1.2	0.9	0.3	-1.9	-0.1	1.6	1.2	-1.5	0.7
Depression (self-reported)	1.1	1.3	3.9	-1.3	-2.0	-0.2	-0.1	-0.3	-1.2	-1.3	-1.5	0.7
Medication: Lansoprazole	0.4	0.4	1.0	-0.7	-0.9	-0.3	0.3	1.0	-0.1	-0.7	-0.9	0.5
Prospective memory result	1.1	1.4	4.9	-1.0	-1.5	-0.7	0.5	0.2	-0.5	-1.0	-1.6	2.2
Lung cancer (father)	1.1	1.2	2.8	-0.7	-1.0	1.3	1.1	-1.5	-0.2	-0.7	-1.7	1.0
Illnesses of mother	0.5	0.6	1.8	0.2	0.4	-0.0	1.3	1.1	-0.4	0.2	1.3	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	5.2	-1.9	-2.3	0.5	0.9	-0.6	-1.6	-1.9	-1.2	0.0
Pulse wave Arterial Stiffness index	0.5	0.6	4.7	-0.5	-2.2	0.2	-0.2	-0.5	0.1	-0.5	0.1	-0.1
Impedance of arm (left)	0.1	0.3	1.2	-0.4	-0.5	-0.0	0.7	0.3	-0.1	-0.4	-0.4	1.1
Arm fat mass (right)	0.8	3.2	9.0	2.1	1.7	-0.7	-3.0	-0.4	1.5	2.1	1.4	1.8
Trunk predicted mass	0.1	0.5	2.8	-0.1	-0.1	-1.2	-0.0	-0.5	-0.5	-0.1	-0.0	-1.7
Standing height	0.1	1.0	2.9	-0.6	-1.2	-0.8	1.5	0.2	-0.9	-0.6	-0.6	-1.7
Length of working week for main job	2.0	2.2	8.5	-0.9	-0.8	-0.2	2.1	2.9	-0.4	-0.9	0.7	2.0
Exposure to tobacco smoke at home	0.5	0.5	1.4	0.9	0.4	0.6	0.3	0.5	0.9	0.9	1.2	0.5
Breastfed as a baby	0.9	1.2	3.5	1.9	0.3	-0.2	-0.1	0.2	1.6	1.9	0.8	-0.2
Tense / ‘highly strung’	0.8	1.3	4.7	-1.3	-2.2	0.3	0.5	-1.1	-0.8	-1.3	-1.4	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.3	-0.6	0.7	-0.3	-0.2	-0.1	-0.5	-0.6	-1.1	0.5
Hair/balding pattern: Pattern 4	0.1	0.2	0.3	0.6	-0.3	-0.5	0.4	0.0	0.5	0.6	-0.5	0.2
Birth weight of first child	0.3	0.6	2.2	-0.2	1.5	-0.8	0.1	0.9	-0.7	-0.2	0.8	-0.3
Peak expiratory flow (PEF)	0.7	1.7	4.2	2.1	0.4	1.3	-0.3	1.0	1.8	2.1	0.7	0.1
Pulse wave reflection index	0.8	0.9	2.0	-1.3	-1.4	0.6	0.5	-0.8	-0.6	-1.3	-1.1	-0.1
Ever highly irritable/argumentative for 2 days	2.4	2.9	16.3	-1.9	-4.0	0.0	0.8	0.9	-1.1	-1.9	0.1	-0.2
Loud music exposure frequency	0.3	0.3	0.9	-0.6	0.5	0.7	-1.0	0.3	-0.2	-0.6	-0.6	0.2
Qualifications: O levels/GCSEs or equivalent	0.7	1.0	5.8	-0.1	-1.1	0.8	1.1	-0.5	0.4	-0.1	0.5	-2.4
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.8	-1.7	-1.6	1.1	1.6	-0.4	-0.3	-1.7	-0.4	-0.9
Blood clot in the leg (DVT)	1.0	1.3	4.0	1.0	-0.9	1.6	-0.2	0.9	1.1	1.0	0.3	2.0
Medication: Paracetamol	0.5	0.8	2.2	0.4	1.1	-0.4	0.7	0.8	0.4	0.4	1.4	-1.5
Headache pain in last month	0.4	0.7	3.5	0.2	-1.9	-0.0	1.4	0.3	-0.0	0.1	0.9	0.3
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	7.7	-2.4	-1.3	0.9	2.2	-0.7	-2.8	-2.4	0.3	-1.0
Glaucoma (self-reported)	1.7	2.0	6.6	1.3	0.5	-2.6	-1.4	1.9	0.8	1.3	0.4	1.2
Gout (self-reported)	1.6	2.2	4.2	2.0	2.0	-0.2	-1.5	-1.3	1.7	2.0	0.4	0.4
Hypothyroidism/myxoedema (self-reported)	3.0	5.9	24.4	2.9	2.1	0.2	-4.9	0.6	2.4	2.9	1.0	0.6
Medication: Amlodipine	0.6	0.8	1.9	0.9	0.8	-0.8	-1.2	0.1	1.0	0.9	0.2	1.4
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.6	-1.6	-0.6	-0.2	1.2	-0.3	-1.2	-1.6	-1.6	-0.8
Birth weight	0.4	1.0	2.4	1.0	1.0	1.5	-0.0	0.5	0.3	1.0	0.9	-1.5
Chronic bronchitis/emphysema (mother)	1.1	1.3	7.4	-0.1	0.4	1.4	-0.0	-2.7	0.3	-0.1	-1.1	0.6
High blood pressure (siblings)	1.0	1.4	2.6	1.2	1.6	-0.5	-0.7	-1.1	1.3	1.2	-1.3	1.2
Forced vital capacity (FVC), Best measure	0.5	1.7	4.9	-1.6	-2.2	0.4	1.2	-0.8	-1.3	-1.6	-1.1	-0.3
Body fat percentage	1.1	4.2	12.8	2.2	2.1	-0.8	-3.6	-0.3	1.9	2.2	1.1	2.3
Leg fat percentage (right)	0.9	3.3	6.7	1.6	2.0	-1.4	-2.6	-1.0	1.5	1.6	1.7	2.4
Arm fat-free mass (right)	0.1	0.3	1.0	-0.1	0.6	-1.0	-0.6	-0.9	-0.5	-0.1	-0.0	-0.5
Exposure to tobacco smoke outside home	1.0	1.3	3.5	0.7	0.2	1.9	-1.4	-0.2	1.5	0.7	0.1	-1.8
Comparative body size at age 10	0.3	0.8	4.3	0.4	-0.1	-0.4	-2.1	0.6	0.6	0.4	-0.4	-1.1
Number of full brothers	0.3	0.3	1.2	-0.5	0.2	-0.3	-0.3	-0.6	-1.1	-0.5	-0.7	-0.6
Worry too long after embarrassment	2.1	3.6	6.9	-2.5	-1.2	-0.6	1.6	-2.1	-2.6	-2.5	-2.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	4.6	-1.5	-0.6	0.9	0.9	-0.7	-0.9	-1.5	-2.1	-1.8
Wheeze or whistling in the chest in last year	0.6	1.0	3.4	0.3	0.9	-1.4	0.4	0.2	0.7	0.3	1.8	1.4
Number of children fathered	0.7	0.8	1.1	1.1	0.3	-0.7	-0.9	0.8	0.8	1.1	1.1	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.9	-0.2	-0.3	-0.0	-0.8	-0.9	0.8	-0.2	-0.9	0.1
Age at first live birth	0.6	1.0	3.3	-0.4	-0.6	-1.8	1.5	0.9	-1.0	-0.4	0.2	-0.7
Pulse wave peak to peak time	0.4	0.5	3.2	0.3	1.8	-0.1	0.5	0.5	-0.3	0.3	-0.0	-0.2
Health satisfaction	0.8	1.0	3.5	-0.0	-0.3	-1.9	-0.1	0.8	0.4	-0.0	1.0	1.8
Shortness of breath walking on level ground	0.5	0.6	3.2	-0.1	-0.5	-1.8	0.3	0.3	-0.1	-0.1	-0.9	1.1
Qualifications: College or University degree	0.7	2.2	9.2	-0.0	-1.2	-3.0	1.2	1.1	0.7	-0.0	2.1	1.4
Eye problems/disorders: None of the above	1.4	1.7	5.6	-1.7	-2.4	1.1	0.9	0.3	-1.2	-1.7	-0.5	0.4
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.4	0.8	1.5	1.2	-0.3	-0.8	1.2	0.8	0.8	-0.0
Emphysema/chronic bronchitis	0.5	0.6	1.9	0.7	1.4	0.4	0.7	-1.0	0.3	0.7	-0.3	0.8
Medication for pain relief, constipation, heartburn	0.6	1.1	2.1	-1.0	-0.6	-0.5	0.7	-1.4	-1.2	-1.0	-1.1	1.5
Neck or shoulder pain in last month	1.0	1.5	4.7	1.4	0.9	0.1	0.2	1.6	0.9	1.4	2.2	-0.3
Medication: Blood pressure	1.3	2.3	4.6	1.7	1.3	-2.1	-1.5	0.7	2.1	1.7	-0.0	1.3
Angina (self-reported)	1.5	2.0	4.8	1.9	2.2	0.7	-1.5	0.1	1.4	1.9	1.2	-0.1
Migraine (self-reported)	1.4	1.7	7.3	1.1	0.5	1.5	0.2	1.2	1.0	1.1	2.7	0.9
Medication: Ibuprofen	2.4	2.9	4.1	2.0	1.7	1.5	-2.0	1.8	2.0	2.0	0.8	-1.1
Medication: Allopurinol	0.8	1.1	3.0	1.7	0.4	-0.1	-0.9	0.3	1.3	1.7	1.2	0.0
Medication: Omeprazole	0.9	1.1	2.7	-1.5	-0.8	1.0	-0.1	0.1	-1.0	-1.5	-1.6	0.1
Medication: Seretide 50 evohaler	0.7	0.8	2.3	-1.0	0.6	0.5	1.5	1.0	-0.7	-1.0	-0.6	-0.4
Mean time to correctly identify matches	0.9	1.8	4.3	-1.4	0.5	-1.3	0.8	-1.2	-2.1	-1.4	-1.1	1.7
Heart disease (mother)	3.2	3.8	9.1	3.0	0.7	1.2	-2.7	-0.4	2.6	3.0	0.0	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.5	0.8	0.4	0.7	-0.6	1.2	0.4	0.8	-0.3	0.8
Whole body fat mass	0.8	3.5	10.7	2.1	2.0	-0.9	-3.3	-0.5	1.6	2.1	1.0	1.9
Leg fat mass (right)	0.9	3.5	8.5	1.8	2.3	-0.9	-2.9	-1.0	1.4	1.8	1.6	2.1
Arm predicted mass (right)	0.1	0.4	1.0	-0.3	0.3	-1.0	-0.5	-1.0	-0.7	-0.3	-0.3	-0.8
Pulse rate, automated reading	1.5	4.8	10.2	-3.2	-0.9	-3.0	1.3	-1.1	-2.8	-3.2	-0.8	-1.0
Alcohol intake frequency.	0.5	1.1	3.5	1.4	0.1	0.2	-0.6	0.2	1.4	1.4	0.5	1.9
Comparative height size at age 10	0.2	1.1	5.6	0.4	-0.0	1.9	0.4	0.2	-0.0	0.4	0.2	-2.4
Number of full sisters	0.6	0.7	1.4	-0.9	-1.2	-0.6	0.5	-0.9	-0.9	-0.9	-1.1	-0.3
Suffer from ‘nerves’	0.6	0.9	2.2	-1.0	-1.5	0.1	1.5	-0.8	-0.8	-1.0	-0.7	0.6
Overall health rating	0.2	0.4	1.3	-0.1	0.4	-0.9	-0.7	0.9	0.1	-0.1	-0.1	1.1
Chest pain or discomfort	0.4	0.6	3.0	0.8	-0.1	0.4	-0.4	0.7	0.8	0.8	0.1	1.7
Had major operations	2.1	2.5	5.1	1.9	-1.2	1.4	-2.0	-0.3	2.3	1.9	-1.1	-1.1
Age at last live birth	0.3	0.5	1.3	0.1	-0.8	-1.0	0.8	-0.2	0.6	0.1	-0.6	-1.1
Family relationship satisfaction	2.4	2.9	5.2	-2.3	-1.5	-1.8	0.8	-1.6	-1.8	-2.3	-2.0	0.4
Leg pain on walking	0.5	0.6	3.3	0.1	-0.5	-1.8	-1.0	0.5	-0.0	0.1	-0.0	0.7
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	6.1	0.9	-0.1	2.5	-1.5	1.3	0.5	0.9	0.5	-1.2
Commuting to job workplace: Car/motor vehicle	2.2	2.5	4.4	-2.1	-1.2	-0.1	1.9	0.8	-2.1	-2.1	1.6	1.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.4	-0.3	0.8	0.0	-0.1	1.2	-0.3	-0.3	-0.0	1.0
Medication: Aspirin	0.7	0.9	2.4	1.2	-0.4	-1.6	-0.2	0.6	1.1	1.2	1.0	0.1
Supplements: Vitamin C	1.4	1.7	6.4	-0.4	-0.9	0.7	0.1	2.5	0.0	-0.4	2.0	1.8
Knee pain experienced in last month	0.2	0.2	0.7	0.2	-0.1	0.8	-0.8	-0.1	0.5	0.2	-0.6	-0.4
Hypertension (Self-reported)	1.3	3.5	7.5	2.5	1.7	-1.2	-2.7	0.7	2.6	2.5	0.3	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.0	-1.4	-1.3	0.8	0.3	0.2	-0.8	-1.4	1.0	0.9
Illnesses of father: Heart disease	1.6	2.2	8.6	1.3	1.7	0.2	-2.9	-0.5	1.1	1.3	-0.5	1.7
Illnesses of siblings: Diabetes	0.9	1.1	4.2	0.4	1.3	0.7	-1.3	-2.0	0.8	0.4	-0.8	-0.8
Smoking status: Previous	1.0	1.5	6.9	0.9	0.3	1.4	-0.9	-0.6	0.6	0.9	1.2	-2.6
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	5.2	0.1	0.3	-0.2	-0.5	-2.2	-0.1	0.1	2.3	-1.1
Whole body fat-free mass	0.1	0.4	1.5	0.3	0.4	-0.8	-0.8	-0.6	-0.3	0.3	0.1	-1.2
Leg fat-free mass (right)	0.1	0.7	3.1	0.9	0.9	-0.0	-1.8	-0.3	0.1	0.9	0.4	-0.9
Arm fat percentage (left)	1.0	4.2	12.2	2.2	2.1	-0.8	-3.5	-0.7	1.9	2.2	1.3	2.2
Average weekly red wine intake	1.6	2.4	17.1	-0.5	0.2	-4.1	0.6	0.5	-0.9	-0.5	0.7	-1.2
Handedness (chirality/laterality): Left-handed	1.7	2.0	7.7	0.9	-2.0	-0.3	1.0	2.8	1.6	0.9	-0.0	-1.0
Mood swings	0.9	1.7	4.8	-1.4	-0.7	2.1	0.2	-0.5	-0.6	-1.4	-1.0	2.2
Loneliness, isolation	1.1	1.6	2.1	-1.4	-1.2	1.4	1.2	-1.3	-1.1	-1.4	0.4	1.4
Long-standing illness, disability or infirmity	0.8	1.2	3.3	1.0	0.2	0.1	-1.5	1.4	1.3	1.0	1.8	0.1
Ever had bowel cancer screening	0.4	0.5	1.8	-0.1	0.5	-0.9	-1.4	0.1	0.7	-0.1	-0.5	0.6
Diabetes diagnosed by doctor	0.7	1.1	2.7	-1.0	0.5	-1.2	-1.5	-1.6	-0.6	-1.0	-1.1	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	3.1	1.2	0.3	0.7	0.6	0.9	1.8	1.2	0.0	-0.4
Friendships satisfaction	0.9	1.1	2.1	-1.4	-1.3	-1.2	1.1	-0.0	-0.7	-1.4	-1.0	0.2
Qualifications: nursing, teaching	0.4	0.6	2.9	0.3	0.4	-0.2	1.7	1.4	0.3	0.3	-0.3	-0.4
Commuting to job workplace: Walk	1.3	1.4	3.4	1.5	1.9	0.9	-1.0	0.0	1.4	1.5	-0.8	0.2
Eye problems/disorders: Cataract	1.1	1.3	2.9	1.4	1.3	0.2	-0.8	-1.7	1.6	1.4	0.0	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.8	-0.4	0.7	0.8	-0.6	1.6	0.7	-0.4	1.3	-1.7
Medication for cholesterol	2.2	3.4	10.1	-2.1	-1.1	0.8	3.2	-0.8	-2.7	-2.1	-1.1	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.9	1.5	0.2	1.7	-0.5	-0.2	1.4	1.5	0.1	-0.8
Back pain experienced in last month	0.2	0.2	0.7	0.8	0.6	0.6	0.0	-0.1	0.1	0.8	0.0	-0.0
Mineral and other dietary supplements	1.4	1.9	3.8	-1.4	-0.6	-1.9	0.7	-1.3	-1.6	-1.4	1.8	0.9
Breast cancer (self-reported)	0.8	0.9	2.2	-0.8	-0.1	0.8	0.5	1.4	-1.2	-0.8	-0.5	-1.5
Asthma (self-reported)	0.2	0.5	3.5	0.0	0.8	0.4	1.9	-0.1	0.1	0.0	0.1	-0.1
Osteoporosis (self-reported)	1.9	2.3	4.0	1.6	-0.3	-0.0	-2.0	2.0	1.3	1.6	-1.8	-1.7
Osteoarthritis (self-reported)	0.5	0.6	2.9	-0.9	-0.2	-0.1	-0.6	-0.7	-0.2	-0.9	-1.7	-0.1
Medication: Aspirin	0.7	1.0	2.8	1.4	-0.2	-1.7	-0.3	0.1	1.2	1.4	0.6	0.2
Medication: Gliclazide	1.7	1.9	6.4	-1.9	-0.3	-0.1	0.1	-2.5	-1.4	-1.9	-1.3	0.6
Illnesses of father: None of the above (group 1)	0.4	0.6	4.4	-0.1	-0.0	-0.4	2.1	0.4	0.2	-0.1	0.1	-0.3
Smoking status: Current	0.5	0.8	6.4	-0.2	0.3	0.1	-0.0	0.5	-0.5	-0.2	-0.5	2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	3.4	-1.5	-0.9	0.8	0.6	-1.2	-0.4	-1.5	-1.8	0.3
Whole body water mass	0.1	0.4	1.6	0.4	0.3	-0.8	-0.8	-0.5	-0.2	0.4	0.2	-1.3
Leg predicted mass (right)	0.1	0.7	2.9	0.9	0.9	-0.1	-1.7	-0.3	0.0	0.9	0.4	-0.9
Arm fat mass (left)	0.8	3.2	9.5	1.9	1.9	-1.0	-3.1	-0.8	1.4	1.9	1.3	1.8
Number of self-reported non-cancer illnesses	1.6	2.7	5.6	2.1	1.8	1.0	-2.2	0.3	2.4	2.1	0.4	-0.2
Average weekly champagne plus white wine intake	1.5	2.1	3.6	-1.9	-1.8	0.3	1.6	0.1	-1.2	-1.9	-1.1	-1.7
Miserableness	0.8	1.3	5.4	0.1	1.0	2.3	0.2	-0.2	0.0	0.1	-0.5	2.3
Guilty feelings	4.2	6.3	14.7	-3.8	-1.2	-1.6	1.4	-2.3	-3.6	-3.8	-1.7	-0.0
Wears glasses or contact lenses	0.6	0.6	1.6	0.7	1.3	-0.3	0.2	-1.0	0.9	0.7	0.2	-1.0
Ever taken oral contraceptive pill	3.7	4.1	25.3	1.8	0.3	5.0	-1.2	0.3	1.3	1.8	1.2	-0.3
Hearing aid user	0.3	0.3	1.1	-0.3	-0.1	-1.1	0.4	0.5	0.5	-0.3	0.9	-0.0
Mother’s age at death	0.3	0.3	0.8	0.3	-0.2	-0.8	0.9	0.7	0.9	0.3	0.1	0.2
Financial situation satisfaction	1.0	1.3	4.9	-1.5	-0.8	-2.2	0.1	0.1	-0.8	-1.5	-1.0	0.2
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.4	-0.1	-0.4	0.1	-0.3	0.5	-0.7	-0.1	0.2	0.6
Commuting to job workplace: Public transport	1.4	1.6	4.3	1.8	1.2	-0.8	-0.4	0.8	2.1	1.8	0.4	-0.7
Eye problems/disorders: Glaucoma	1.8	2.2	6.2	1.5	1.0	-2.5	-1.7	0.7	1.5	1.5	0.2	1.5
Medication: Blood pressure	2.3	4.3	14.1	2.7	0.8	-0.2	-3.8	0.1	3.0	2.7	1.0	-0.0
Pain type(s) experienced in last month: Hip pain	0.8	1.1	3.0	0.8	-1.6	1.7	-1.0	0.4	0.4	0.8	1.2	-0.5
Supplements: Fish oil (including cod liver oil)	1.4	1.8	4.6	1.5	0.6	2.1	-0.3	1.1	1.9	1.5	-1.1	-0.8
High cholesterol (Self-reported)	1.1	2.0	7.8	1.5	0.7	0.7	-2.8	-0.0	2.0	1.5	-0.2	1.0
Medication: Bendroflumethiazide	2.2	3.3	10.6	1.7	2.1	-1.1	-3.3	0.6	2.6	1.7	0.3	0.8
Medication: Paracetamol	0.8	1.2	3.8	1.1	1.1	0.1	-0.6	0.8	0.8	1.1	1.2	-1.9
Medication: Lisinopril	1.1	1.4	4.6	1.3	0.6	-2.1	-0.9	1.3	1.4	1.3	0.1	0.0
Medication: Atorvastatin	0.9	1.1	5.1	1.1	0.5	0.5	-0.1	0.2	2.3	1.1	0.3	-1.2
Illnesses of father: High blood pressure	0.9	1.2	5.3	-0.8	1.0	-0.6	-1.6	-2.3	-0.5	-0.8	-0.3	0.1
Alcohol drinker status: Never	0.8	1.0	3.3	-0.6	-0.7	1.4	0.9	-1.8	0.0	-0.6	-0.9	0.8
Ever smoked	0.6	1.1	2.7	1.6	0.1	1.4	-0.8	0.1	0.9	1.6	0.8	-0.6
Basal metabolic rate	0.1	0.4	1.3	0.5	0.5	-0.8	-1.1	-0.5	-0.1	0.5	0.3	-0.8
Leg fat percentage (left)	0.8	2.8	8.5	1.3	2.0	-1.0	-2.9	-0.7	1.1	1.4	1.5	1.9
Arm fat-free mass (left)	0.0	0.2	0.5	0.4	0.3	-0.7	-0.5	0.0	-0.1	0.4	0.2	-0.6
Number of operations (self-reported)	1.4	2.1	8.2	1.9	0.5	2.9	-0.5	0.5	1.8	1.9	0.0	-0.2
Average weekly beer plus cider intake	0.5	0.7	2.7	0.9	1.0	1.6	0.9	-0.3	0.0	0.9	-0.6	-0.5
Irritability	0.9	1.6	5.4	-1.0	-2.3	1.9	0.1	0.6	-0.6	-1.0	0.5	1.5
Risk taking	1.4	2.0	7.0	0.1	0.1	2.4	0.4	-0.2	0.2	0.1	2.2	-2.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.6	0.8	0.3	-0.5	-0.9	0.6	1.6	0.8	-1.4	0.6
Fractured/broken bones in last 5 years	1.1	1.5	4.8	1.1	1.3	0.2	-1.8	0.7	0.6	1.1	2.2	-0.2
Age started oral contraceptive pill	0.2	0.2	0.7	-0.3	-0.4	-0.6	0.9	0.3	-0.0	-0.3	0.4	0.7
Diastolic blood pressure, automated reading	0.5	1.6	7.3	0.4	1.1	-2.7	-1.1	0.4	-0.3	0.4	1.3	-1.5
Ever depressed for a whole week	0.9	1.1	2.9	-1.4	-1.7	-0.2	1.4	0.1	-0.8	-1.4	-0.1	-0.9
Unable to work because of sickness or disability	0.2	0.3	1.2	0.5	-0.3	-0.4	-0.6	1.1	0.1	0.5	0.7	0.3
Commuting to job workplace: Cycle	4.7	5.6	15.5	3.4	1.9	-1.0	-1.1	1.7	3.9	3.4	1.7	0.7
Myopia	1.1	1.6	4.3	-1.5	-0.6	-0.5	0.0	1.0	-1.9	-1.5	-2.1	-0.6
Vascular/heart problems diagnosed by doctor	2.0	5.4	10.7	-3.2	-1.4	0.9	3.3	-0.8	-3.3	-3.2	-1.2	-1.5
Cholesterol lowering medication	0.9	1.3	4.8	1.1	-0.0	0.1	-2.2	-0.2	1.6	1.1	1.4	0.3
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.5	-1.2	-1.1	1.1	0.1	0.4	-0.8	-1.2	-1.6	-0.5
Pain experienced in last month	0.4	0.6	2.2	-0.7	0.4	-1.5	-0.9	-0.6	-0.1	-0.7	-0.6	0.8
Supplements: Calcium	1.8	1.9	7.0	1.4	-0.4	0.2	-2.6	-0.5	1.7	1.4	0.5	1.7
Basal cell carcinoma (self-reported)	0.7	0.9	6.1	0.5	0.1	-0.8	-0.6	0.4	0.6	0.5	-0.1	-2.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.8	-0.3	0.0	-0.2	-1.1	0.9	0.2	-0.2	-0.1	1.3
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.2	1.1	-0.5	1.4	-0.3	1.2	1.2	1.1	0.4	1.8
Heart disease (siblings)	1.2	1.5	3.7	0.3	0.9	1.7	-1.9	-1.6	0.6	0.3	-0.6	1.6
Alcohol drinker status: Previous	1.1	1.3	2.8	1.2	0.4	1.1	-0.7	1.2	1.7	1.2	1.5	-0.3
Pack years of smoking	0.0	0.1	0.3	-0.2	0.3	-0.0	0.5	0.1	-0.1	-0.2	-0.3	-0.3
Impedance of whole body	0.2	0.9	2.4	-1.0	-1.0	-0.1	1.6	0.7	-0.7	-1.0	-0.5	1.3
Leg fat mass (left)	0.8	3.2	9.4	1.7	2.4	-0.7	-3.1	-1.0	1.2	1.7	1.4	1.8
Arm predicted mass (left)	0.0	0.1	0.5	0.3	0.2	-0.6	-0.4	-0.1	-0.2	0.3	0.1	-0.7