Best TWAS P=1.23e-11 · Best GWAS P=2.34e-13 conditioned to 0.00342
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | PDE8B | 0.38 | 0.35 | lasso | 3 | 0.34 | 3.3e-27 | 6.7 | 6.8 | 1.2e-11 | 0.86 | 0.10 | 0.90 | TRUE |
| 2 | GTEx | Thyroid | ZBED3 | 0.25 | 0.12 | lasso | 12 | 0.14 | 4.9e-11 | 6.4 | 5.1 | 3.0e-07 | 0.68 | 0.22 | 0.78 | FALSE |