[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr5:75,669,474-77,412,011

Best TWAS P=1.23e-11 · Best GWAS P=2.34e-13 conditioned to 0.00342

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Thyroid	PDE8B	0.38	0.35	lasso	3	0.34	3.3e-27	6.7	6.8	1.2e-11	0.86	0.10	0.90	TRUE
2	GTEx	Thyroid	ZBED3	0.25	0.12	lasso	12	0.14	4.9e-11	6.4	5.1	3.0e-07	0.68	0.22	0.78	FALSE