TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
:
←
→
chr5:101,392,473-103,244,640
Best TWAS P=3.69e-10 · Best GWAS P=2.06e-11 conditioned to 0.0124
101.5M
102M
102.5M
103M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellar Hemisphere
PAM
0.27
0.1
lasso
4
0.13
0.00027
-6.6
-6.3
3.7e-10
0.88
0.02
0.98
TRUE
2
GTEx
Pituitary
PPIP5K2
0.15
0.1
enet
13
0.11
0.00122
-4.7
5.4
5.5e-08
-0.76
0.17
0.42
FALSE