Best TWAS P=9.12e-11 · Best GWAS P=2.74e-10 conditioned to 0.0436
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | FKBP5 | 0.04 | 0.05 | lasso | 2 | 0.04 | 5.4e-05 | 5.9 | 5.8 | 5.0e-09 | -0.50 | 0.02 | 0.96 | FALSE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | TULP1 | 0.09 | 0.02 | blup | 58 | 0.02 | 6.1e-02 | -5.7 | -6.5 | 9.1e-11 | 0.78 | 0.01 | 0.76 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TULP1 | 0.09 | 0.06 | lasso | 4 | 0.07 | 6.2e-08 | 5.9 | -5.7 | 1.3e-08 | 0.64 | 0.00 | 1.00 | FALSE |