[Hub]/) : Traits : Hypothyroidism (self reported) :

chr6:35,216,296-35,942,313

Best TWAS P=9.12e-11 · Best GWAS P=2.74e-10 conditioned to 0.0436

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 The Cancer Genome Atlas Lung Adenocarcinoma FKBP5 0.04 0.05 lasso 2 0.04 5.4e-05 5.9 5.8 5.0e-09 -0.50 0.02 0.96 FALSE
2 The Cancer Genome Atlas Pancreatic Adenocarcinoma TULP1 0.09 0.02 blup 58 0.02 6.1e-02 -5.7 -6.5 9.1e-11 0.78 0.01 0.76 TRUE
3 The Cancer Genome Atlas Prostate Adenocarcinoma TULP1 0.09 0.06 lasso 4 0.07 6.2e-08 5.9 -5.7 1.3e-08 0.64 0.00 1.00 FALSE