TWAS
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Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr11:46,622,392-48,028,343
Best TWAS P=2.31e-07 · Best GWAS P=3.53e-07 conditioned to 1
46.6M
46.8M
47M
47.2M
47.4M
47.6M
47.8M
48M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Breast Mammary Tissue (Female)
MADD
0.13
0.04
lasso
3
0.05
0.013
5.1
5.2
2.3e-07
0.98
0.02
0.72
TRUE