TWAS
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Traits
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Hypothyroidism (self reported)
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chr11:34,460,769-35,949,179
Best TWAS P=3.03e-16 · Best GWAS P=9.85e-19 conditioned to 9.19e-06
34.4M
34.6M
34.8M
35M
35.2M
35.4M
35.6M
35.8M
36M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SLC1A2
0.03
0
blup
180
0.01
0.05320
7.0
-8.2
3.0e-16
-0.69
0.03
0.49
TRUE
1
NTR
Blood
CD44
0.03
0
blup
684
0.01
0.00087
7.1
-5.3
9.6e-08
-0.46
0.06
0.40
FALSE