TWAS hub - MADD

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3200	0.0810	5.0e-11	0.172	0.117	0.178	0.182	0.180	1.7e-20	4.0e-14	3.3e-21	1.4e-21	2.4e-21
2	GTEx	Artery Aorta	0.0920	0.0460	5.2e-03	0.027	NA	0.044	NA	0.042	1.2e-02	NA	1.9e-03	NA	2.2e-03
3	GTEx	Artery Tibial	0.0901	0.0385	5.2e-04	0.004	NA	0.019	NA	0.018	1.5e-01	NA	1.1e-02	NA	1.3e-02
4	GTEx	Brain Cerebellar Hemisphere	0.4400	0.1220	8.6e-05	0.138	NA	0.191	NA	0.211	2.2e-04	NA	1.2e-05	NA	4.0e-06
5	GTEx	Brain Cerebellum	0.2100	0.0890	1.0e-03	0.002	NA	0.113	NA	0.081	2.8e-01	NA	3.3e-04	NA	2.2e-03
6	GTEx	Breast Mammary Tissue (Female)	0.1315	0.0834	3.2e-02	0.041	NA	0.017	NA	0.050	2.3e-02	NA	9.8e-02	NA	1.3e-02
7	GTEx	Cells Transformed fibroblasts	0.1900	0.0660	5.6e-05	0.005	NA	0.089	NA	0.067	1.3e-01	NA	3.3e-07	NA	8.9e-06
8	GTEx	Esophagus Mucosa	0.2660	0.0910	1.3e-04	0.037	NA	0.115	NA	0.075	1.5e-03	NA	4.1e-08	NA	9.4e-06
9	GTEx	Esophagus Muscularis	0.1320	0.0570	7.2e-04	0.072	NA	0.114	NA	0.110	3.6e-05	NA	2.0e-07	NA	3.4e-07
10	GTEx	Heart Left Ventricle	0.1371	0.0514	1.2e-04	0.013	NA	0.055	NA	0.031	6.7e-02	NA	7.0e-04	NA	9.1e-03
11	GTEx	Pituitary	0.4210	0.1300	1.3e-06	0.321	NA	0.343	NA	0.388	7.8e-09	NA	1.9e-09	NA	8.9e-11
12	GTEx	Thyroid	0.1070	0.0560	5.5e-03	-0.003	NA	0.009	NA	0.000	7.3e-01	NA	6.1e-02	NA	3.2e-01
13	METSIM	Adipose	0.0452	0.0228	2.4e-03	0.024	0.013	0.015	0.018	0.016	1.3e-04	3.4e-03	2.3e-03	8.3e-04	1.7e-03
14	NTR	Blood	0.0122	0.0064	8.0e-03	0.007	0.002	0.006	0.002	0.005	2.4e-03	8.3e-02	4.7e-03	4.5e-02	9.0e-03
15	ROSMAP	Brain Pre-frontal Cortex	0.3320	0.0580	0.0e+00	0.156	0.231	0.232	0.224	0.229	1.3e-19	2.7e-29	1.9e-29	2.4e-28	5.8e-29
16	TCGA	Breast Invasive Carcinoma	0.1119	0.0416	8.6e-09	0.028	0.051	0.056	NA	0.053	1.6e-06	9.0e-11	1.4e-11	NA	5.7e-11
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.2046	0.0747	5.2e-07	0.067	0.064	0.080	NA	0.077	5.7e-08	9.1e-08	2.4e-09	NA	5.5e-09
18	TCGA	Brain Lower Grade Glioma	0.0808	0.0428	2.4e-04	0.012	0.029	0.046	NA	0.048	1.5e-02	2.5e-04	5.9e-06	NA	3.1e-06
19	TCGA	Lung Squamous Cell Carcinoma	0.1571	0.0600	4.6e-09	0.053	0.080	0.061	NA	0.064	1.0e-06	2.2e-09	1.8e-07	NA	9.0e-08
20	TCGA	Prostate Adenocarcinoma	0.1538	0.0731	1.3e-03	0.043	0.027	0.062	NA	0.056	2.5e-05	6.8e-04	4.5e-07	NA	1.6e-06
21	TCGA	Testicular Germ Cell Tumors	0.2090	0.1150	1.1e-03	0.037	0.074	0.067	NA	0.027	1.9e-02	1.3e-03	2.2e-03	NA	3.8e-02
22	TCGA	Thyroid Carcinoma	0.0700	0.0440	1.3e-03	-0.003	0.024	0.029	NA	0.012	9.6e-01	1.8e-03	6.7e-04	NA	2.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Comparative body size at age 10	21.4	59.0	94.7	7.2	6.3	5.3	5.9	8.0	7.9	8.5	9.0	7.4	7.2	8.4	8.2	4.5	5.7	6.6	9.7	8.8	9.7	7.3	8.8	7.3	8.6
Arm fat percentage (left)	16.3	65.1	132.2	6.9	5.6	4.0	8.1	10.4	11.5	7.8	8.6	6.1	10.2	10.4	6.6	0.9	2.9	5.2	11.1	8.6	11.5	6.0	8.6	7.3	8.6
Suffer from ‘nerves’	16.2	25.5	67.9	-4.7	-2.8	-3.7	-3.9	-5.4	-6.7	-5.3	-5.7	-5.4	-3.7	-8.2	-5.4	-2.6	-3.8	-3.7	-7.2	-5.3	-6.4	-3.5	-5.5	-3.5	-4.1
Fasting Glucose	14.5	17.3	45.2	6.0	5.1	6.3	-2.5	-0.7	2.1	0.9	5.4	6.2	-1.5	6.4	2.3	4.8	4.9	6.7	3.9	4.1	2.5	2.5	4.1	-0.5	0.1
Arm fat percentage (right)	14.3	56.4	118.8	6.3	5.0	3.6	7.6	9.8	10.9	7.3	8.1	5.7	9.6	9.9	6.0	0.7	2.6	4.7	10.3	7.8	10.8	5.5	7.9	6.7	7.9
HDL Cholesterol	12.4	20.7	64.6	-0.2	3.0	2.1	-7.1	-8.0	-5.0	-5.2	-2.0	1.1	-7.8	-1.8	-3.8	3.5	1.5	1.8	-5.2	-3.6	-5.9	-2.2	-3.3	-6.9	-6.0
Age when periods started (menarche)	12.3	29.5	46.0	-4.8	-4.4	-4.5	-3.4	-5.0	-4.9	-6.0	-6.7	-5.2	-5.4	-6.3	-5.2	-4.2	-4.6	-5.3	-6.5	-6.4	-6.8	-5.5	-5.4	-5.9	-5.5
Trunk fat percentage	12.1	48.7	102.0	6.4	5.8	3.7	6.8	8.7	10.0	6.6	7.4	5.4	9.0	8.9	5.2	0.9	2.2	5.1	9.2	7.5	10.1	5.0	7.4	6.1	7.3
Body fat percentage	11.4	45.0	102.0	5.9	4.8	3.0	6.9	8.7	10.1	6.1	6.9	4.7	9.4	8.5	4.7	0.6	1.6	4.5	8.9	7.2	10.0	4.5	6.8	5.9	7.2
BMI	11.0	63.7	125.4	6.6	4.9	4.3	7.7	10.1	11.0	8.2	8.8	6.2	10.4	10.2	6.8	1.8	3.2	5.2	11.1	8.6	11.2	6.2	8.1	7.5	8.2
Arm fat mass (left)	10.9	44.7	80.3	5.9	6.3	4.5	5.5	7.8	8.7	6.6	7.7	5.9	7.7	8.4	5.6	2.1	4.0	5.4	9.0	6.9	8.8	5.7	7.5	6.0	6.6
Body Mass Index (BMI) (2010)	10.5	14.4	31.0	2.9	3.7	2.1	4.0	5.0	5.6	3.5	4.5	2.7	5.0	4.7	3.2	0.3	1.3	2.4	5.6	3.7	5.2	2.5	3.9	3.0	3.2
Arm fat mass (right)	10.5	43.4	77.6	5.7	5.9	4.2	5.7	7.9	8.6	6.7	7.6	5.6	7.8	8.2	5.5	1.8	3.7	5.0	8.8	6.8	8.7	5.6	7.3	6.0	6.8
Trunk fat mass	9.5	40.9	71.9	5.9	6.5	4.3	5.2	7.3	8.1	6.4	7.3	5.6	7.8	7.8	5.0	2.1	3.4	5.4	8.3	6.8	8.5	5.4	7.1	5.8	6.5
Body mass index (BMI)	9.4	39.9	85.4	5.1	4.7	3.5	6.0	8.1	9.2	6.0	6.8	4.9	8.0	8.2	5.3	1.1	2.9	4.0	8.6	6.5	8.9	4.9	6.6	5.9	6.5
Chronotype (morning person)	9.1	21.1	60.5	3.6	2.7	0.8	5.6	5.8	2.7	7.8	4.4	2.9	6.3	2.4	3.9	1.3	2.2	2.9	4.9	5.0	5.5	4.1	5.9	5.3	6.8
Whole body fat mass	9.1	37.9	69.2	5.5	5.8	3.9	5.3	7.2	8.0	6.1	6.9	5.2	7.8	7.4	4.8	1.9	3.1	5.0	8.1	6.5	8.3	5.1	6.8	5.6	6.4
Worry (Nagel 2018)	8.2	17.3	55.5	-4.4	-3.2	-4.9	-1.1	-3.1	-5.4	-2.4	-5.0	-5.7	-0.5	-7.4	-4.6	-3.1	-4.5	-3.7	-5.6	-4.1	-4.4	-3.0	-4.5	-1.9	-1.9
Leg fat mass (left)	8.0	31.2	59.9	4.9	4.8	3.4	4.8	6.5	7.6	5.3	6.3	4.5	7.2	7.0	4.1	2.0	2.9	4.4	7.5	6.0	7.7	4.5	5.9	5.0	5.7
Leg fat percentage (left)	7.4	26.8	80.3	3.9	2.2	1.1	6.2	7.3	9.0	4.2	4.7	2.4	8.4	6.6	2.8	-0.5	-0.0	2.4	6.9	5.2	8.3	2.7	4.5	4.5	5.6
Leg fat mass (right)	7.3	28.2	56.0	4.6	4.5	3.0	4.8	6.4	7.4	5.0	5.9	4.2	7.1	6.6	3.9	1.5	2.4	4.0	7.1	5.7	7.5	4.2	5.6	4.8	5.5
Miserableness	7.3	12.6	59.1	-3.9	-3.0	-5.0	0.8	-0.8	-4.8	-1.3	-3.5	-5.8	1.0	-7.7	-2.2	-3.2	-4.8	-3.9	-3.7	-2.9	-3.0	-1.7	-2.8	0.3	0.1
Alzheimer’s Disease (including proxy)	7.2	10.4	24.8	-2.9	-3.3	-4.3	-0.8	-2.9	-4.3	-2.0	-3.6	-4.3	-0.6	-5.0	-4.2	-2.3	-2.9	-2.8	-3.1	-3.2	-3.4	-3.3	-3.3	-2.6	-1.8
Eye problems/disorders: Diabetes related eye disease	7.2	7.9	17.2	2.4	1.6	0.9	3.4	4.1	3.5	3.3	3.0	2.0	3.2	3.3	3.0	0.0	1.0	1.4	4.1	2.6	3.6	1.7	3.7	2.2	2.8
Nervous feelings	7.1	13.3	33.6	-4.0	-3.9	-5.0	0.1	-1.5	-4.1	-2.0	-4.0	-5.2	0.5	-5.8	-3.6	-4.0	-4.6	-4.3	-4.3	-3.5	-3.4	-3.0	-3.7	-1.2	-1.1
Hip circumference	6.7	29.0	51.4	4.2	4.8	3.5	4.6	6.7	7.0	5.3	6.3	4.4	6.6	6.1	4.6	1.3	2.8	3.8	7.1	5.7	7.2	5.0	5.7	5.8	5.7
Leg fat percentage (right)	6.4	23.0	72.6	3.6	1.8	0.8	6.0	6.9	8.5	3.8	4.0	2.1	7.9	6.1	2.4	-1.0	-0.6	1.9	6.3	4.8	7.8	2.2	4.1	4.0	5.2
Prostate Cancer	6.3	8.9	17.2	-2.5	-3.2	-3.1	-0.3	-1.7	-3.4	-2.6	-3.0	-2.8	-2.1	-3.0	-2.8	-2.8	-3.1	-3.2	-4.0	-3.6	-4.1	-3.3	-3.4	-2.6	-2.7
Waist circumference	6.3	23.1	49.7	3.8	6.3	4.2	3.4	5.2	7.1	4.3	5.4	4.1	5.8	6.1	4.0	1.6	2.5	4.0	6.1	4.7	6.2	4.2	4.6	4.1	4.2
High blood pressure	6.2	17.2	59.6	-2.7	-4.4	-6.0	6.0	4.7	-1.3	4.8	-1.5	-5.3	7.7	-5.3	0.8	-3.0	-4.1	-3.7	0.5	0.8	2.1	1.1	0.5	5.9	5.6
Hypertension (Self-reported)	5.9	16.5	62.3	-2.5	-4.5	-5.8	5.9	4.7	-1.2	4.8	-1.2	-5.0	7.9	-4.9	0.6	-2.7	-3.6	-3.3	0.6	1.1	2.3	1.1	0.6	6.0	5.7
Mood swings	5.9	10.7	48.8	-3.0	-3.2	-5.1	1.0	-0.9	-4.5	-0.6	-3.7	-5.0	1.5	-7.0	-3.0	-2.9	-4.2	-3.4	-3.5	-2.3	-2.3	-1.8	-2.0	0.0	0.6
Fluid intelligence score	5.8	12.0	25.9	-1.8	-0.3	-0.9	-3.5	-5.1	-4.9	-3.6	-2.6	-1.7	-3.8	-4.0	-4.8	-0.7	-2.0	-0.7	-4.9	-3.5	-5.1	-2.9	-3.6	-3.9	-4.1
Myopia	5.5	8.0	20.7	-1.7	-1.0	0.1	-3.9	-4.5	-4.5	-3.1	-2.5	-1.2	-3.5	-2.0	-3.5	0.9	0.7	-0.3	-4.0	-2.6	-4.2	-2.0	-3.0	-2.0	-3.4
Vascular/heart problems diagnosed by doctor	5.5	14.9	60.2	1.6	3.4	4.9	-5.8	-4.8	0.9	-5.1	0.7	4.1	-7.8	4.3	-1.3	2.2	3.3	2.5	-1.2	-1.7	-2.8	-1.7	-1.2	-6.0	-5.8
Verbal and Numeric Reasoning (VNR)	5.3	12.6	30.3	-1.9	0.8	0.2	-4.2	-5.5	-5.1	-3.5	-2.9	-1.2	-4.9	-3.9	-3.8	-0.0	-1.7	-0.4	-5.1	-3.5	-5.3	-2.5	-3.8	-3.5	-4.7
Neuroticism (Nagel 2018)	5.2	12.1	65.6	-3.4	-2.3	-4.9	1.1	-1.2	-5.3	-0.4	-3.6	-5.4	1.2	-8.1	-2.9	-3.2	-4.6	-3.2	-3.9	-2.3	-2.7	-1.5	-2.7	0.3	0.5
Impedance of leg (right)	5.1	24.8	41.1	-3.6	-5.8	-5.3	-2.1	-4.4	-3.8	-5.6	-6.3	-5.6	-2.7	-5.7	-6.0	-3.2	-6.4	-4.2	-6.1	-4.4	-4.3	-5.8	-5.8	-5.2	-4.2
Knee pain experienced in last month	5.0	7.8	17.6	-2.6	-0.5	-0.4	-3.8	-4.2	-2.9	-3.2	-2.8	-1.7	-2.3	-2.2	-3.8	0.1	-0.4	-1.2	-4.1	-3.4	-3.9	-2.4	-3.5	-2.0	-3.4
Hypothyroidism (self reported)	4.8	11.0	26.8	2.5	3.3	2.1	2.1	3.8	5.2	3.2	3.3	2.3	2.5	2.9	4.1	2.0	3.0	2.5	4.5	3.3	4.4	4.0	3.8	2.8	3.2
Medication: Metformin	4.7	6.6	17.7	2.5	3.6	2.2	1.8	2.2	4.2	1.9	3.7	2.9	3.1	3.8	1.7	1.0	0.7	2.7	2.8	2.4	3.3	1.1	1.8	1.0	1.6
Weight	4.7	23.2	46.8	4.3	6.8	4.8	2.0	4.0	4.0	5.1	6.0	5.2	4.3	5.0	4.0	3.5	4.9	5.2	5.6	4.7	4.8	5.2	5.6	4.4	4.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.7	5.5	12.5	-1.5	-1.2	-1.0	-2.1	-2.9	-3.0	-1.9	-3.5	-1.4	-2.8	-2.4	-2.6	-1.2	-1.9	-1.3	-3.4	-2.4	-2.9	-2.5	-2.3	-1.9	-2.8
Depressed Affect (Nagel 2018)	4.6	9.6	63.2	-2.4	-1.6	-4.4	1.1	-1.0	-5.1	-0.4	-2.8	-4.8	1.7	-8.0	-2.5	-2.5	-4.4	-2.2	-3.3	-1.5	-2.0	-1.3	-1.7	0.7	0.9
Loneliness, isolation	4.6	6.3	36.4	-1.7	-0.4	-1.6	-1.5	-3.1	-6.0	-1.3	-1.8	-2.2	-0.8	-5.5	-2.0	-0.4	-1.9	-0.9	-3.6	-1.9	-3.6	-1.1	-2.0	-0.7	-1.1
Cardiovascular Disease	4.5	15.0	69.2	-0.6	-2.3	-4.6	6.2	5.0	-1.5	5.8	0.8	-3.2	8.3	-3.7	1.6	-1.5	-2.5	-1.4	1.8	2.3	3.0	1.7	2.3	5.6	6.4
Prospective memory result	4.5	5.5	19.4	1.4	0.7	0.9	2.1	2.6	0.6	4.4	1.9	1.8	2.6	1.5	2.5	1.2	2.2	1.7	2.7	2.4	2.5	2.5	2.7	3.8	3.0
Intelligence (Savage-Jansen 2018)	4.4	13.6	32.6	-1.7	0.3	-0.4	-4.5	-5.7	-4.9	-4.2	-2.9	-1.6	-4.9	-3.9	-4.1	-0.2	-1.9	-0.5	-5.1	-3.6	-5.2	-3.1	-3.8	-4.2	-4.7
Alcohol intake frequency.	4.2	9.7	34.4	3.0	4.0	2.5	2.2	2.8	5.9	1.3	4.4	2.9	3.0	5.4	1.8	1.4	0.6	2.7	4.2	2.7	4.2	1.3	2.7	-0.5	1.7
Systolic Blood Pressure	4.1	20.8	112.4	-2.3	-3.0	-4.8	3.8	2.3	-7.1	5.0	-0.4	-5.3	5.5	-10.6	2.0	1.2	-1.8	-1.5	-0.6	2.2	0.6	4.9	1.1	7.9	7.0
Leg fat-free mass (right)	4.1	21.6	54.0	3.8	7.3	5.8	-0.2	2.0	1.0	4.9	6.1	5.9	1.4	3.8	4.6	5.0	7.2	5.6	4.5	3.8	2.4	5.8	5.5	3.9	3.1
Impedance of leg (left)	4.0	19.6	35.4	-3.0	-5.2	-4.9	-1.7	-3.9	-3.4	-5.0	-5.4	-5.2	-2.0	-5.2	-5.6	-2.7	-5.9	-3.5	-5.3	-3.7	-3.6	-5.3	-5.2	-4.7	-3.5
Leg predicted mass (right)	4.0	21.3	53.6	3.8	7.3	5.7	-0.2	2.0	1.0	4.9	6.0	5.8	1.5	3.7	4.6	4.9	7.1	5.6	4.5	3.8	2.4	5.7	5.5	3.9	3.0
Illnesses of father: High blood pressure	4.0	4.9	16.6	-2.7	-3.1	-3.6	0.7	-0.3	-2.6	0.3	-2.7	-3.7	1.5	-4.1	-2.1	-0.9	-1.7	-2.5	-2.5	-1.8	-1.7	-1.1	-1.5	0.9	0.5
Eye problems/disorders: Cataract	3.9	4.6	7.6	1.8	2.7	2.5	0.5	1.5	2.8	2.2	2.1	2.3	1.1	2.7	2.5	1.7	2.2	2.2	2.7	2.0	2.4	2.3	2.0	1.7	1.4
Frequency of depressed mood in last 2 weeks	3.8	5.3	24.3	-1.5	-1.1	-2.4	-0.7	-2.0	-3.6	-2.2	-2.5	-2.7	-0.7	-4.9	-2.8	-2.1	-2.6	-1.7	-3.1	-1.6	-2.3	-1.6	-1.7	-1.3	-0.8
Leg fat-free mass (left)	3.8	20.0	50.0	3.7	7.1	5.6	-0.2	2.0	1.1	4.7	5.7	5.7	1.4	3.8	4.4	4.7	6.8	5.4	4.4	3.7	2.4	5.5	5.3	3.8	2.9
Leg predicted mass (left)	3.8	20.1	49.9	3.7	7.1	5.6	-0.1	2.1	1.3	4.8	5.7	5.7	1.5	3.9	4.5	4.6	6.7	5.3	4.4	3.7	2.5	5.5	5.3	3.8	3.0
Neuroticism score	3.8	7.9	51.1	-2.3	-1.0	-3.6	-0.0	-1.7	-5.5	-0.6	-2.7	-3.8	0.2	-7.2	-2.1	-1.9	-3.1	-2.0	-3.5	-1.8	-2.8	-0.6	-1.7	-0.1	0.4
Glaucoma (self-reported)	3.8	4.4	11.7	-1.0	1.9	0.3	-3.0	-3.4	-2.3	-2.4	-0.7	-0.4	-2.3	-1.4	-2.3	0.9	-0.3	0.4	-2.2	-2.2	-3.0	-1.7	-2.1	-3.0	-3.4
Forced vital capacity (FVC), Best measure	3.8	14.0	45.6	-1.2	0.7	1.1	-5.9	-6.3	-6.4	-2.6	-1.6	0.5	-6.8	-3.1	-2.2	3.3	2.5	0.9	-4.4	-3.0	-5.8	-0.7	-2.3	-3.7	-4.3
Breastfed as a baby	3.7	4.5	15.1	-0.8	0.8	1.1	-3.9	-3.2	-3.4	-2.4	-0.4	0.1	-3.8	-1.4	-1.0	1.8	2.1	0.5	-1.9	-1.8	-3.4	-0.1	-1.0	-1.7	-2.6
Mouth/teeth dental problems: Bleeding gums	3.7	4.8	17.1	0.0	-3.8	-3.8	3.8	2.5	-0.1	1.6	0.2	-1.6	4.1	-0.2	-0.5	-2.7	-3.2	-1.8	0.8	0.5	1.4	-2.2	0.5	0.4	2.1
Eye problems/disorders: Glaucoma	3.7	4.3	11.3	0.8	3.1	1.6	-3.4	-3.3	-2.3	-2.1	0.1	1.3	-2.7	-0.3	-1.9	1.4	0.6	2.1	-1.3	-1.1	-2.4	-1.4	-0.6	-3.1	-3.3
Medication: Blood pressure	3.7	7.0	25.1	-2.1	-3.5	-4.0	4.3	3.3	-0.2	3.1	-0.5	-3.1	5.0	-1.9	0.2	-2.4	-2.7	-2.8	0.5	0.2	1.3	-0.2	-0.0	3.1	3.2
Medication: Bendroflumethiazide	3.7	5.6	15.4	-1.8	-2.5	-3.8	3.5	2.3	-1.5	2.3	-0.7	-3.4	3.9	-3.9	0.1	-1.8	-2.6	-2.2	-0.1	0.1	0.5	0.5	-0.1	2.9	2.8
Bipolar Disorder (2018)	3.6	5.7	14.5	-2.8	-1.7	-0.7	-3.6	-3.8	-2.4	-3.7	-2.5	-2.3	-1.6	-2.3	-3.7	0.8	-0.4	-1.3	-3.1	-1.6	-2.2	-1.8	-2.2	-1.7	-2.0
Hand grip strength (left)	3.6	9.5	33.0	-2.7	-2.0	-2.1	-3.2	-3.5	-5.7	-1.7	-3.2	-2.5	-4.6	-5.4	-1.7	0.3	1.0	-1.7	-4.1	-3.1	-4.9	-0.4	-1.8	-2.0	-2.1
Pain all over the body in last month	3.6	3.8	6.8	2.3	2.1	1.8	0.9	1.6	1.8	1.5	2.0	2.4	1.8	2.1	1.4	1.6	1.7	2.1	2.0	2.6	2.5	2.0	2.3	1.8	1.9
Migraine (self-reported)	3.6	4.5	14.2	-1.1	0.4	0.8	-3.1	-3.3	-2.6	-2.7	-1.6	-0.5	-3.8	-1.9	-1.9	1.3	0.8	-0.1	-2.8	-1.9	-3.0	-0.7	-1.5	-2.0	-2.8
Depression (Nagel 2018)	3.5	5.2	20.2	-2.0	-0.6	-1.7	-1.4	-2.3	-3.5	-1.9	-2.7	-2.5	-1.0	-4.5	-3.0	-1.9	-2.0	-1.5	-3.3	-1.9	-2.6	-1.4	-2.4	-0.7	-1.3
Neuroticism (2016)	3.5	5.1	24.2	-2.2	-1.6	-2.4	-1.2	-1.9	-4.3	-1.2	-2.2	-3.1	-0.1	-4.9	-2.1	-1.1	-2.1	-1.5	-2.9	-1.6	-2.5	-1.2	-1.9	0.2	-0.6
LDL Cholesterol	3.4	5.4	9.7	-2.8	-1.6	-2.2	-0.1	-0.9	-0.8	-2.4	-2.7	-3.1	-0.5	-2.7	-1.9	-3.1	-2.9	-3.0	-2.3	-2.9	-1.9	-2.5	-2.8	-2.0	-2.4
Father’s age at death	3.3	4.5	11.6	-2.9	-2.2	-1.6	-0.6	-0.8	1.0	-1.8	-3.4	-2.3	-0.8	-0.7	-1.7	-2.5	-2.6	-3.1	-2.4	-2.5	-1.2	-2.2	-3.4	-0.6	-2.0
Medication: Blood pressure	3.3	5.7	20.3	-1.2	-1.6	-2.6	3.4	2.7	-1.6	3.5	0.3	-2.6	4.5	-3.5	1.2	-0.5	-0.9	-1.2	0.7	0.9	1.2	2.1	0.7	4.3	3.6
Forced expiratory volume in 1-second (FEV1), predicted	3.3	6.8	17.9	-1.5	1.4	1.2	-4.1	-4.2	-3.7	-2.8	-0.9	-0.2	-4.2	-2.2	-1.6	2.2	2.1	0.3	-3.2	-2.6	-4.2	-0.3	-1.7	-2.6	-3.0
Diabetes diagnosed by doctor	3.3	5.3	13.9	2.8	3.2	2.2	1.3	2.0	2.9	1.1	3.7	2.7	2.0	3.3	2.0	0.9	1.1	2.5	3.2	2.4	2.6	1.2	2.4	0.7	1.2
Alzheimer’s Disease (in mother)	3.2	3.7	9.6	-2.1	-2.4	-3.1	0.5	-0.8	-1.4	-0.3	-2.3	-2.8	1.0	-2.2	-2.7	-2.0	-1.8	-2.1	-2.0	-2.1	-1.4	-2.4	-1.9	-1.2	-0.6
Ever used hormone-replacement therapy (HRT)	3.2	4.1	14.1	1.1	1.3	1.6	1.5	2.9	3.8	0.7	1.6	1.3	1.0	2.8	2.5	-0.0	1.1	0.6	3.0	1.9	2.7	2.4	2.1	2.4	1.5
Neuroticism	3.1	7.5	53.5	-2.4	-0.5	-3.2	0.0	-1.5	-5.6	0.1	-2.6	-3.9	0.4	-7.3	-1.6	-1.9	-2.9	-1.7	-3.1	-1.5	-2.5	0.1	-1.5	0.9	0.6
Tense / ‘highly strung’	3.1	5.2	14.4	-3.0	-2.4	-3.5	0.1	-0.9	-2.2	-0.9	-2.7	-3.6	1.4	-3.8	-2.5	-1.5	-2.5	-2.4	-2.5	-2.1	-1.7	-1.7	-2.5	0.1	-0.7
Severe depression (siblings)	3.0	3.3	10.0	-1.7	-0.8	-0.6	-2.1	-2.7	-3.2	-0.7	-1.8	-1.0	-2.1	-1.9	-1.8	0.4	0.2	-0.9	-2.8	-2.2	-3.0	-1.3	-2.0	-1.0	-1.7
Lung cancer (father)	3.0	3.5	12.0	-0.2	-0.8	-1.1	-1.9	-2.8	-3.5	-1.1	-2.3	-0.6	-1.9	-2.1	-2.7	-0.3	-0.5	-0.2	-2.8	-1.5	-2.4	-2.1	-1.1	-2.2	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.0	9.5	35.2	-1.3	-0.0	0.5	-4.7	-5.0	-4.6	-3.1	-1.6	0.2	-5.9	-2.2	-1.8	1.9	1.4	-0.2	-3.6	-2.7	-4.8	-1.1	-2.3	-3.7	-3.8
Loud music exposure frequency	3.0	3.3	10.5	1.3	0.5	-0.1	2.7	2.7	2.5	2.0	2.0	0.7	3.2	2.0	1.4	0.3	-0.3	0.3	2.5	1.7	2.6	0.6	1.8	1.2	2.0
Headache pain in last month	3.0	5.1	9.3	-2.3	-1.2	-1.9	-0.6	-2.0	-1.1	-2.6	-2.9	-3.0	-0.9	-2.3	-3.0	-1.8	-2.6	-2.3	-2.7	-2.6	-2.1	-2.5	-2.8	-2.6	-1.8
Medication: Gliclazide	3.0	3.4	8.6	2.1	1.7	2.1	0.4	1.1	2.2	0.9	2.3	2.4	1.5	2.9	1.4	1.5	1.6	2.4	2.0	2.2	2.3	1.3	1.5	1.2	1.2
Medication: Lisinopril	3.0	3.9	14.6	0.8	-1.6	-2.1	3.6	3.0	0.1	2.0	0.8	-1.3	3.8	-1.5	1.2	-1.0	-2.3	-0.6	1.3	1.7	2.2	0.4	1.3	2.6	2.9
Deep venous thrombosis (DVT) (self-reported)	3.0	3.8	14.4	3.8	2.6	1.5	0.7	-0.2	-0.3	1.1	3.0	2.6	0.4	1.2	0.5	3.4	0.9	3.5	0.8	2.5	1.4	0.3	2.1	-1.2	0.9
Systolic blood pressure, automated reading	2.8	8.0	41.0	-0.8	-0.5	-1.2	2.1	2.4	-2.1	3.8	0.1	-2.1	3.6	-4.7	2.2	1.4	0.7	-0.2	0.8	2.3	1.8	4.6	1.7	6.4	5.0
Blood clot in the leg (DVT)	2.8	3.6	15.9	4.0	2.5	1.4	0.5	-0.4	-0.5	0.7	2.8	2.7	0.1	1.1	0.2	3.2	0.6	3.5	0.5	2.5	1.2	-0.1	1.9	-1.6	0.7
Chest pain or discomfort	2.8	4.0	11.6	-0.9	-0.1	-0.9	-2.1	-3.4	-3.1	-2.5	-1.6	-1.8	-0.6	-3.3	-2.2	1.1	-1.6	-0.0	-3.0	-1.4	-2.2	-1.7	-2.3	-1.3	-1.7
Forced vital capacity (FVC)	2.7	10.5	33.5	-0.4	1.3	1.1	-5.4	-5.3	-5.4	-2.4	-1.3	0.7	-5.8	-2.8	-1.8	2.8	2.5	1.3	-3.6	-2.3	-5.0	-0.5	-1.4	-3.5	-3.7
Breast Cancer	2.6	6.3	15.1	-2.8	-2.3	-3.9	1.0	-0.7	-1.2	-0.2	-2.7	-3.9	1.6	-3.6	-3.0	-2.1	-3.6	-2.8	-2.6	-2.8	-1.7	-2.8	-2.8	-1.2	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	2.5	5.8	21.7	-0.4	1.5	1.9	-4.1	-3.5	-0.6	-1.4	0.3	1.5	-3.6	2.4	-1.0	3.0	4.7	1.3	-1.1	-2.2	-2.6	-0.6	-0.9	-3.5	-3.2
Ever highly irritable/argumentative for 2 days	2.5	3.0	11.7	1.4	3.4	2.5	-0.6	-0.5	-0.1	0.9	2.2	1.9	0.1	0.4	1.5	2.9	2.1	2.6	1.1	1.8	1.0	2.6	1.0	1.1	1.1
Hypothyroidism/myxoedema (self-reported)	2.5	4.8	14.6	0.9	1.4	0.6	2.2	3.2	3.8	2.0	2.0	0.4	2.7	1.3	2.7	0.5	1.4	0.8	3.1	1.9	3.2	2.6	2.2	2.3	2.4
Birth weight	2.5	5.3	16.2	-1.9	1.6	-0.4	-3.0	-3.2	-4.0	-0.2	-2.0	-1.2	-3.3	-3.9	-1.3	1.1	0.8	-0.2	-3.0	-2.8	-4.0	-0.3	-1.2	-1.8	-1.8
Eye problems/disorders: None of the above	2.5	2.8	5.2	-1.1	-2.2	-1.9	-0.5	-1.3	-1.8	-2.2	-1.9	-1.9	-1.4	-2.3	-1.6	-1.5	-1.7	-1.8	-2.1	-1.3	-1.6	-1.6	-1.7	-1.6	-0.8
Average weekly champagne plus white wine intake	2.5	3.5	12.4	-0.5	-2.1	-2.3	-0.1	-1.5	-2.0	-0.8	-1.5	-1.4	-0.0	-2.0	-3.5	-1.3	-2.7	-0.8	-2.1	-1.5	-1.6	-3.3	-1.7	-2.3	-1.3
Ever taken oral contraceptive pill	2.5	2.8	10.7	-1.4	0.2	0.6	-2.5	-2.2	-2.1	-2.0	-0.8	0.2	-3.3	-1.2	-1.0	-0.3	0.2	-0.7	-1.4	-1.9	-2.9	-0.5	-1.2	-1.5	-2.6
Heart attack/myocardial infarction (self-reported)	2.5	3.2	7.9	2.2	2.8	1.7	0.4	0.9	-0.1	1.5	2.2	1.9	1.8	0.6	1.5	1.9	1.5	2.4	1.9	2.3	1.6	2.2	2.2	1.4	1.5
Blood White Count	2.4	17.9	104.0	1.0	-2.8	-0.6	5.5	6.5	10.2	1.2	2.5	0.3	4.7	6.4	2.9	-0.4	-0.7	-1.2	5.6	3.6	7.5	1.8	1.9	2.7	3.6
Type 2 Diabetes (T2D) (2018)	2.4	4.6	11.4	2.5	2.1	1.2	2.2	2.3	3.2	1.1	3.0	2.1	3.4	3.2	0.9	-0.1	-1.0	2.0	2.8	2.2	2.9	-0.1	1.7	0.4	1.4
Other serious medical condition/disability diagnosed by doctor	2.4	3.1	12.1	0.6	3.0	2.5	-1.2	0.1	-0.0	0.9	2.0	1.6	-0.2	0.5	1.7	2.4	3.5	1.9	1.4	1.0	0.3	3.0	1.6	2.2	0.6
Standing height	2.4	24.2	102.0	-0.8	5.2	3.3	-8.0	-7.6	-10.1	-0.9	-0.8	1.4	-6.8	-5.8	-2.0	5.6	4.8	3.4	-5.2	-2.9	-7.6	1.2	-0.9	-2.5	-4.0
Illnesses of siblings: Diabetes	2.4	3.0	8.8	1.5	0.6	1.1	1.4	2.2	2.9	1.4	1.5	1.8	2.0	3.0	1.2	0.2	0.6	0.9	1.7	2.0	2.6	0.8	1.5	2.0	1.7
Bipolar Disorder (2011)	2.3	2.3	6.8	-2.6	-1.0	-0.6	-2.1	-2.3	-1.3	-1.4	-2.5	-1.9	-0.5	-2.0	-2.4	0.2	-0.5	-1.4	-1.8	-0.6	-0.7	-0.7	-1.1	-0.2	-0.3
Heel T-Score	2.3	18.4	73.6	1.5	0.6	2.7	-6.7	-6.0	0.5	-2.8	-0.0	3.5	-6.6	5.5	-2.1	6.0	8.6	2.8	-1.3	-2.4	-2.9	-1.9	-0.7	-7.1	-5.2
Stomach or abdominal pain in last month	2.3	2.9	8.3	-0.8	-1.4	-1.7	-1.2	-2.0	-2.6	-2.0	-1.4	-1.5	-0.1	-2.1	-2.9	-0.2	-0.6	-0.7	-2.6	-1.4	-1.9	-2.2	-1.4	-1.9	-1.2
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.6	15.9	-1.6	-1.0	-1.6	-1.0	-2.3	-3.5	-1.2	-2.1	-2.0	-0.4	-4.0	-1.9	-0.6	-1.8	-1.0	-2.7	-1.4	-2.2	-1.1	-1.8	-0.6	-0.8
Townsend deprivation index at recruitment	2.2	3.0	19.1	-1.2	0.1	-0.6	-1.8	-2.5	-4.4	-1.2	-1.2	-1.5	-0.9	-3.3	-1.4	-0.1	-0.2	-0.7	-2.5	-1.4	-2.7	-0.3	-1.2	-0.4	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	3.0	13.5	-1.9	-0.3	-0.7	-1.6	-1.9	-3.2	-1.5	-1.9	-1.7	-1.0	-3.7	-1.6	-0.6	-0.6	-1.4	-2.4	-1.4	-2.3	0.2	-1.5	0.1	-0.8
Diabetes (self-reported)	2.2	3.5	7.7	1.9	2.0	1.3	1.8	2.2	2.5	1.0	2.8	1.8	2.3	2.7	1.7	-0.1	0.2	1.3	2.6	1.9	2.4	0.8	1.7	1.1	1.4
Worrier / anxious feelings	2.2	4.2	11.6	-2.1	-1.5	-2.7	-0.2	-1.6	-3.2	-0.7	-2.5	-2.6	0.0	-3.4	-2.4	-1.7	-2.0	-1.9	-2.9	-1.9	-2.2	-1.6	-2.0	-1.0	-0.5
Hair/balding pattern: Pattern 4	2.2	5.3	12.3	2.0	2.0	1.3	2.3	3.4	3.5	1.2	1.7	1.1	2.5	2.0	2.9	0.4	0.4	1.5	3.3	2.7	3.4	2.1	2.3	3.1	1.9
High blood pressure (siblings)	2.2	3.2	11.2	-0.9	-2.4	-3.1	2.7	1.7	-0.3	1.6	-0.8	-2.8	3.3	-2.4	-0.1	-0.6	-1.4	-1.6	-0.3	0.2	1.0	0.1	0.2	1.8	2.8
Medication: Paracetamol	2.2	3.4	8.3	2.4	2.0	1.7	1.1	1.3	1.6	0.8	2.9	2.3	0.6	2.4	1.4	1.1	1.2	1.9	2.7	2.3	2.1	1.9	2.1	0.1	1.5
Taking other prescription medications	2.1	3.2	11.2	0.8	3.4	2.0	0.5	0.9	2.3	0.9	2.5	1.2	2.1	1.5	1.2	2.5	2.1	2.0	1.7	1.3	1.7	2.5	1.1	1.1	1.1
Sitting height	2.1	15.1	81.7	-1.8	1.3	0.5	-5.7	-5.7	-9.0	-0.3	-1.2	-0.7	-3.9	-6.4	-2.2	4.6	4.3	1.7	-4.7	-2.6	-6.1	0.9	-1.3	-0.8	-2.2
Heart attack	2.1	2.6	6.3	1.9	2.5	1.4	0.5	1.0	0.1	1.3	2.2	1.6	1.9	0.7	1.3	1.6	1.2	2.1	1.9	2.1	1.5	2.0	2.0	1.3	1.4
Hair/balding pattern: Pattern 3	2.1	3.1	9.4	0.3	-0.1	-0.3	2.9	3.1	2.1	2.8	1.0	0.2	3.0	1.0	1.0	-1.5	-1.2	-0.3	1.6	1.4	2.2	0.8	1.1	2.5	2.4
Forced expiratory volume in 1-second (FEV1)	2.1	7.1	24.3	-0.9	0.3	0.1	-4.1	-4.1	-4.1	-2.7	-1.5	-0.0	-4.9	-2.3	-1.5	1.3	1.3	-0.1	-3.0	-2.4	-4.3	-1.0	-1.5	-3.4	-3.3
Medication for cholesterol, blood pressure or diabetes	2.1	3.5	12.5	-0.4	0.2	0.9	-2.6	-2.3	0.8	-3.1	-0.8	0.7	-3.5	1.5	-1.7	-0.0	0.3	-0.3	-1.4	-1.6	-1.7	-1.9	-1.4	-3.5	-2.9
Medication: Amlodipine	2.1	3.0	12.5	-1.0	-1.3	-1.6	2.3	1.7	-1.2	3.0	1.1	-1.2	3.5	-1.9	0.8	-0.2	-0.7	-0.4	0.8	0.8	0.8	1.6	0.4	3.4	2.5
Basal metabolic rate	2.1	11.8	38.4	2.6	6.2	4.7	-1.4	0.3	-0.6	3.3	4.3	4.4	0.3	1.9	2.8	4.5	5.9	4.6	2.5	2.2	0.6	4.3	3.7	2.3	1.4
Height	2.0	39.3	141.6	0.0	7.8	5.4	-10.8	-9.2	-11.9	-0.9	-0.9	2.6	-8.9	-6.6	-1.9	7.8	6.8	5.5	-5.5	-3.0	-9.0	2.8	-0.1	-2.6	-5.0
Medication: Atenolol	2.0	2.5	6.8	-2.2	-2.6	-2.6	0.4	-0.4	-1.2	0.7	-1.9	-2.4	0.9	-1.8	-1.3	-1.2	-1.2	-2.3	-1.5	-1.7	-1.1	-1.3	-1.6	-0.2	-0.3
Medication: Levothyroxine sodium	2.0	3.3	13.2	0.0	1.1	0.8	1.5	2.7	3.6	1.2	1.9	0.2	2.1	1.7	2.1	0.5	1.6	0.5	2.6	1.3	2.4	2.3	1.2	2.2	1.6
Supplements: Vitamin C	2.0	2.4	7.3	-1.9	-1.2	-0.2	-1.8	-1.7	0.4	-2.7	-1.4	-1.3	-1.4	0.1	-2.2	0.4	-0.2	-0.9	-1.7	-1.8	-1.3	-1.3	-2.4	-1.5	-2.2
Guilty feelings	2.0	3.1	19.4	-0.4	-0.6	-1.4	1.0	0.2	-3.6	2.5	-0.9	-1.2	1.0	-4.4	0.9	0.4	-0.1	-0.2	-0.9	1.0	-0.0	2.0	0.6	2.8	2.7
Cholesterol lowering medication	2.0	2.9	11.1	0.7	1.1	-1.2	3.1	2.8	2.3	1.8	0.8	-0.7	3.3	0.2	1.1	-1.5	-1.7	-0.3	1.1	0.9	2.2	0.1	1.4	1.0	2.5
Blood Platelet Count	1.9	21.8	93.7	0.1	1.4	3.7	-6.2	-6.8	-9.7	1.0	-2.1	1.3	-8.7	-5.8	2.0	7.0	6.1	3.1	-4.4	-0.5	-5.2	4.8	0.3	0.5	-0.7
Hand grip strength (right)	1.9	5.3	26.2	-1.8	-1.0	-2.0	-1.8	-2.3	-4.5	-0.7	-2.6	-2.4	-2.8	-5.1	-1.3	0.4	0.3	-1.2	-3.2	-2.1	-3.4	-0.0	-0.9	-1.1	-0.9
Maternal smoking around birth	1.9	2.8	8.7	1.0	0.7	0.4	1.9	1.6	-0.2	2.4	1.3	0.4	2.4	-0.1	1.3	0.9	1.4	1.3	1.4	1.9	1.7	2.2	2.1	2.7	2.9
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.1	4.4	-2.1	-1.3	-1.6	-0.5	-0.9	-1.4	-0.9	-1.9	-2.1	0.4	-2.1	-1.8	-1.1	-1.3	-1.7	-1.8	-1.7	-1.6	-1.1	-1.7	-0.5	-0.8
Peak expiratory flow (PEF)	1.9	4.3	13.4	-1.3	-0.5	-0.6	-2.6	-2.4	-3.6	-2.2	-1.9	-1.0	-3.7	-2.4	-1.4	-0.3	1.1	-1.1	-2.4	-2.2	-3.6	-0.6	-1.0	-2.1	-2.1
Comparative height size at age 10	1.9	10.6	33.6	0.8	5.2	3.9	-5.1	-4.3	-4.5	0.5	1.1	2.5	-3.9	-1.8	0.1	5.8	5.1	3.9	-1.6	-0.4	-3.2	2.6	0.9	-1.0	-1.6
Hearing aid user	1.9	2.1	8.3	0.7	-0.4	0.0	1.7	2.1	2.6	1.1	0.9	0.2	2.9	1.7	-0.0	-0.2	0.2	0.3	2.0	1.4	2.3	0.5	1.1	1.8	1.5
Average weekly beer plus cider intake	1.9	2.7	12.5	-0.3	-1.4	-0.2	-2.5	-2.7	-3.5	-0.2	-1.4	-0.3	-1.6	-2.1	-1.9	1.6	1.0	0.7	-2.5	-0.8	-2.2	-0.8	-1.0	-0.5	-1.0
Diastolic blood pressure, automated reading	1.9	6.0	21.9	-1.2	-2.3	-3.3	2.6	2.2	-1.3	2.2	-1.4	-3.6	4.0	-4.7	0.4	-0.2	-1.2	-1.6	-0.0	1.1	1.5	2.0	0.8	3.9	4.0
Triglycerides	1.8	3.0	11.6	-0.1	-1.6	-1.8	2.3	2.4	1.6	1.0	-0.6	-1.2	3.1	-0.6	0.1	-2.9	-3.4	-1.4	1.0	0.8	1.9	-1.1	0.2	1.4	1.5
Diabetes (father)	1.8	2.2	6.4	0.3	1.2	0.5	1.6	2.1	2.5	1.0	1.6	0.6	1.9	1.5	1.4	-0.2	0.9	0.3	2.0	1.2	2.0	1.7	1.4	1.9	1.8
Current tobacco smoking	1.8	2.9	17.2	-0.7	-0.5	-0.5	-2.0	-2.6	-4.2	-1.3	-1.1	-1.0	-1.5	-3.2	-2.1	0.9	0.1	0.2	-2.1	-0.9	-2.4	-0.4	-1.1	-0.7	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.1	21.3	0.3	1.5	1.5	-3.0	-2.6	-0.3	-0.6	0.6	1.7	-2.9	2.4	-0.7	2.7	4.6	1.5	-0.3	-1.4	-1.7	-0.2	-0.1	-3.0	-2.4
Hair/balding pattern: Pattern 2	1.8	2.3	7.8	-1.1	-1.9	-0.9	-1.6	-2.2	-2.8	-1.3	-1.6	-0.9	-1.9	-1.7	-1.4	-0.0	0.4	-1.1	-1.9	-1.4	-2.0	-0.7	-1.2	-1.3	-0.8
Medication: Cholesterol lowering	1.8	2.9	6.7	1.7	1.6	0.6	1.8	1.9	0.3	2.4	1.3	0.6	2.6	0.3	2.3	0.6	0.5	1.3	2.1	1.9	2.0	1.7	2.0	2.2	2.1
Age at last live birth	1.8	2.7	8.1	-1.5	-0.9	-0.3	-1.9	-1.8	-1.2	-2.7	-1.8	-1.3	-2.9	-1.3	-1.1	-0.6	0.3	-1.4	-1.8	-2.0	-2.1	-0.7	-1.6	-1.7	-2.0
Commuting to job workplace: Car/motor vehicle	1.8	2.0	7.2	-0.9	-1.0	0.0	-1.3	-1.7	0.6	-2.2	-0.2	0.1	-1.0	1.3	-2.3	0.3	-0.2	-0.4	-0.9	-1.6	-1.3	-2.0	-1.7	-2.4	-2.7
Illness, injury, bereavement, stress in last 2 years	1.8	2.3	8.5	1.3	1.2	1.7	0.7	1.7	2.9	1.1	1.0	1.7	0.0	2.7	2.2	0.6	0.6	1.2	1.8	1.3	2.0	1.0	1.3	0.9	0.6
Smoking status: Current	1.8	2.9	17.0	-0.7	-0.5	-0.7	-1.7	-2.5	-4.1	-1.3	-1.1	-1.1	-1.3	-3.3	-2.3	0.7	-0.2	0.1	-2.1	-0.9	-2.3	-0.6	-1.2	-0.8	-1.2
Whole body water mass	1.8	10.2	36.6	1.9	5.9	4.6	-2.7	-1.1	-2.2	2.6	3.5	4.1	-1.3	0.7	2.3	4.8	6.0	4.2	1.4	1.3	-1.0	3.8	3.0	1.4	0.4
Alcohol drinker status: Never	1.8	2.2	13.2	1.2	0.4	0.6	1.6	1.8	3.6	0.6	1.0	0.6	1.7	2.6	0.7	-0.1	-1.0	0.6	1.9	1.3	2.6	0.0	0.6	0.2	1.0
Fed-up feelings	1.7	3.0	19.2	-0.1	0.1	-2.4	2.2	0.8	-2.4	0.1	-0.1	-2.2	2.5	-4.4	0.0	-1.2	-2.5	-0.6	-0.3	1.0	0.7	0.7	0.5	1.8	2.5
Hearing difficulty/problems with background noise	1.7	2.7	11.9	-2.1	-1.8	-1.2	-0.4	-0.9	-1.6	-1.8	-2.1	-2.8	-0.8	-3.5	-0.7	-1.2	-2.1	-1.6	-1.7	-0.9	-1.2	-0.3	-1.9	0.7	-0.3
Pulse rate	1.7	2.9	10.3	1.0	3.2	3.1	-2.0	-1.2	0.9	-1.4	2.1	1.9	-0.9	1.9	0.9	2.9	2.4	2.0	0.7	0.6	0.1	1.6	0.3	-0.3	-0.9
Whole body fat-free mass	1.7	9.8	36.4	1.7	5.7	4.5	-2.7	-1.1	-2.2	2.6	3.4	3.9	-1.2	0.7	2.2	4.7	6.0	4.1	1.3	1.2	-1.0	3.8	2.9	1.4	0.3
Medication for cholesterol	1.7	2.6	9.8	0.5	1.1	1.3	-3.0	-2.3	-0.2	-2.9	-0.7	0.7	-3.1	0.1	-1.2	0.9	0.6	0.8	-0.9	-0.9	-1.3	-0.9	-0.7	-2.7	-2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.1	6.6	1.0	-0.6	-0.3	2.0	1.9	0.7	1.9	2.1	0.9	2.6	2.1	0.4	-0.4	0.7	0.5	1.9	1.4	1.6	0.3	1.4	1.3	1.8
Pain experienced in last month	1.7	2.8	6.0	1.7	0.8	1.3	0.9	1.2	0.7	2.2	2.5	2.3	-0.0	2.2	2.4	1.4	2.2	1.5	1.8	1.6	1.2	1.6	1.9	1.3	1.3
High blood pressure (mother)	1.6	2.3	8.6	-1.6	-0.1	-2.2	1.7	1.3	-1.6	1.9	-0.2	-2.3	2.5	-2.9	0.5	-0.8	-1.2	-1.4	-0.3	-0.4	-0.5	0.6	0.2	2.0	1.6
Medication: Ramipril	1.6	2.0	7.5	-1.5	-1.9	-2.1	0.6	0.2	-2.1	1.0	-1.1	-2.4	2.2	-2.7	-0.6	-0.4	-0.5	-1.2	-0.9	-0.5	-0.5	0.5	-0.6	1.9	1.3
Pulse rate, automated reading	1.6	5.1	22.3	1.6	4.7	4.0	-3.0	-1.7	1.2	-1.7	2.0	2.7	-1.8	2.9	0.2	2.6	3.1	2.9	0.9	0.3	-0.3	1.1	0.4	-0.9	-2.1
Tinnitus: Yes, now most or all of the time	1.6	1.8	6.2	-0.8	-1.7	-1.9	0.4	-0.5	-0.8	0.1	-2.5	-1.5	-0.2	-1.5	-1.4	-1.6	-2.0	-1.4	-1.6	-1.2	-0.7	-1.9	-1.0	-1.2	-0.4
Fractured/broken bones in last 5 years	1.6	2.1	6.3	-1.6	-1.9	-0.7	-0.4	-1.3	-2.3	-0.5	-2.0	-1.2	-1.4	-2.5	-0.6	-1.0	-1.6	-1.6	-1.9	-1.0	-1.6	-0.7	-1.6	0.5	-0.9
Medication for hormone replacement therapy	1.5	1.7	6.0	1.4	0.8	2.0	-1.0	-0.7	-0.2	0.1	1.2	2.5	-1.8	2.0	0.8	1.6	2.3	1.6	0.6	0.9	0.0	1.2	0.9	-0.0	-0.5
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	7.9	0.9	2.8	1.5	-0.8	-1.0	-1.3	1.6	1.3	1.7	-0.1	-0.1	0.9	2.3	2.1	2.1	0.1	0.7	-0.3	1.5	0.9	0.5	0.6
Mouth/teeth dental problems	1.5	2.3	8.0	-1.1	2.3	2.5	-2.8	-1.3	0.1	-1.3	-0.1	0.7	-2.8	0.2	1.3	1.4	2.5	0.3	-0.5	-0.9	-1.4	1.9	-0.5	0.4	-1.4
Trunk fat-free mass	1.5	8.8	28.4	0.3	4.6	3.7	-4.4	-3.4	-4.6	1.0	1.6	2.7	-3.2	-1.5	0.6	4.6	5.3	3.1	-1.0	-0.7	-3.4	2.5	1.0	-0.2	-1.6
Trunk predicted mass	1.5	8.7	29.1	0.4	4.6	3.8	-4.3	-3.2	-4.5	1.1	1.7	2.7	-3.1	-1.4	0.7	4.7	5.4	3.2	-0.9	-0.5	-3.3	2.6	1.1	-0.1	-1.5
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	7.5	-0.9	-1.4	-1.1	-0.4	-0.9	-0.3	-1.2	-0.4	-0.3	-0.6	0.8	-2.2	-1.3	-0.4	-1.2	-0.7	-1.8	-1.6	-2.1	-1.2	-2.7	-1.8
Qualifications: nursing, teaching	1.5	2.4	6.9	0.9	1.0	1.7	1.0	1.7	1.3	1.5	1.2	1.2	0.3	1.3	2.5	0.1	1.5	1.0	2.0	1.5	1.5	2.3	1.7	2.6	1.5
Mother’s age at death	1.5	1.9	4.7	-1.4	-1.6	-1.3	-0.3	-1.0	-0.3	-0.7	-2.2	-1.3	-0.7	-1.2	-1.2	-1.6	-2.1	-1.8	-1.6	-1.5	-1.0	-1.6	-1.8	-1.2	-1.2
Unable to work because of sickness or disability	1.5	1.9	7.7	-0.1	1.7	1.5	-1.1	-0.7	-2.5	1.1	0.8	0.6	-0.3	-1.3	0.2	1.8	2.8	1.3	0.2	0.4	-0.8	2.6	0.9	2.0	0.7
Lupus	1.4	2.0	7.3	0.0	2.0	2.0	-2.5	-2.3	-1.2	-1.6	0.2	0.9	-2.7	-0.4	0.2	2.0	1.0	1.0	-0.8	-0.4	-1.3	0.9	-0.7	-1.1	-1.5
Smoking Status	1.4	3.5	12.3	-1.1	-0.2	-0.2	-2.6	-2.8	-3.5	-1.5	-1.2	-1.1	-1.5	-2.5	-2.6	1.4	1.2	0.2	-2.2	-1.6	-2.9	-0.7	-1.4	-1.1	-2.3
Alcohol intake versus 10 years previously	1.4	2.0	6.5	0.9	0.7	0.3	2.1	2.0	2.4	2.0	1.0	1.1	2.0	2.5	0.8	-0.8	-0.1	0.3	1.9	1.1	1.9	-0.1	1.3	0.6	0.9
Arm predicted mass (right)	1.4	7.2	27.6	1.8	5.2	3.8	-2.5	-1.4	-2.1	1.7	2.8	3.2	-1.0	0.1	1.4	4.4	4.7	3.9	0.9	1.1	-0.9	2.9	2.3	0.7	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	5.6	0.1	-1.0	-1.6	-0.1	-0.7	-1.1	-1.2	-1.1	-0.7	-0.7	-0.7	-1.3	-1.6	-1.8	-0.8	-1.2	-0.8	-1.0	-2.2	-0.6	-2.4	-1.1
Primary Biliary Cirrhosis	1.3	1.9	6.3	1.4	1.5	1.8	-0.9	-1.2	-1.5	1.3	1.2	2.0	-1.1	-0.3	1.2	2.5	1.9	2.0	-0.1	1.1	-0.1	1.6	1.3	0.0	0.7
Hayfever, allergic rhinitis or eczema	1.3	2.8	9.0	-1.3	-1.8	-3.0	0.8	-0.7	-1.7	-1.1	-1.0	-2.4	0.8	-2.4	-1.8	-1.5	-2.6	-1.8	-1.6	-1.5	-1.3	-2.0	-1.3	-1.5	-0.3
Illnesses of siblings	1.3	1.9	8.5	-0.3	1.0	1.0	-1.7	-1.6	-0.8	-2.4	0.0	0.6	-2.9	0.2	-0.1	-0.2	0.3	-0.4	-0.2	-1.2	-1.8	-0.6	-0.7	-2.5	-2.5
Falls in the last year	1.3	1.8	7.6	-1.0	0.1	0.9	-1.8	-1.6	-2.8	-0.1	-0.4	-0.4	0.2	-1.9	-0.5	2.3	1.9	0.8	-1.4	-0.0	-1.2	1.6	-0.5	2.1	0.2
Illnesses of mother	1.3	1.6	7.8	1.0	0.5	2.3	-0.8	-0.2	2.1	-0.7	0.9	2.0	-1.6	2.8	1.0	0.6	1.3	1.0	1.4	0.7	0.8	0.8	0.2	-0.4	-0.7
Arm fat-free mass (right)	1.3	6.6	24.3	1.6	4.9	3.7	-2.6	-1.5	-2.3	1.4	2.6	3.0	-1.1	-0.2	1.4	4.3	4.6	3.7	0.7	1.0	-1.0	2.9	2.2	0.7	-0.1
Pulse wave peak to peak time	1.3	1.6	4.0	-0.3	-1.8	-1.4	-0.6	-1.1	-1.6	-1.1	-0.9	-0.5	-0.7	-0.7	-1.7	-1.4	-1.0	-0.8	-1.3	-1.1	-1.4	-2.0	-1.2	-2.0	-1.3
Medication: Seretide 50 evohaler	1.3	1.5	4.6	0.5	2.1	1.6	-0.5	-0.1	-0.7	1.8	0.6	0.9	1.0	-0.1	1.1	2.1	1.7	1.6	0.5	1.0	0.5	1.5	1.0	2.0	0.8
Lung FVC	1.2	6.3	18.3	-1.9	-1.9	-0.9	-3.5	-3.5	-2.6	-2.8	-2.4	-0.9	-4.3	-1.4	-2.3	0.9	1.1	-1.1	-2.8	-2.7	-3.6	-1.6	-2.5	-2.6	-3.5
Diabetes (mother)	1.2	1.5	5.7	2.4	1.5	0.7	0.7	0.8	0.5	-0.4	2.2	1.8	0.6	1.7	0.0	0.1	-0.4	1.7	1.2	1.4	1.1	-0.7	1.5	-0.9	0.1
Medication: Simvastatin	1.2	1.8	4.9	0.7	1.2	-0.2	2.0	2.2	1.4	1.6	0.6	-0.4	1.9	-0.0	2.2	-0.7	-0.2	-0.1	1.4	0.9	1.7	1.2	1.5	1.5	1.9
Length of working week for main job	1.2	1.3	4.2	1.7	0.4	1.5	-1.4	-1.1	-0.3	-0.6	1.0	2.0	-1.4	1.4	0.3	1.8	1.4	1.8	0.5	1.3	0.5	0.5	0.6	-0.4	-0.2
Exposure to tobacco smoke at home	1.2	1.4	6.9	-1.2	-1.7	-1.7	1.9	1.0	-0.1	1.1	-0.6	-1.3	2.6	-0.4	-0.4	-1.0	-1.3	-1.5	-0.1	-0.0	0.6	-0.4	-0.7	0.9	1.2
Shortness of breath walking on level ground	1.2	1.4	6.1	1.4	1.0	0.8	0.6	0.6	0.0	0.4	1.9	0.9	2.5	0.3	-0.0	1.1	-0.4	1.7	1.3	1.9	1.4	0.9	0.8	1.5	1.0
Long-standing illness, disability or infirmity	1.2	1.9	8.7	0.1	2.6	1.9	-1.6	-0.9	-0.4	0.7	0.7	0.3	0.6	-0.5	0.2	3.0	2.4	2.0	0.2	0.5	-0.0	1.9	0.5	1.4	0.2
Pack years of smoking	1.2	1.7	5.3	1.1	1.0	1.1	-0.5	-0.4	-1.9	1.8	0.9	0.9	1.2	-0.2	-0.1	1.6	2.3	2.3	0.7	1.5	0.4	1.5	1.0	1.7	1.2
Time employed in main current job	1.1	1.2	4.0	-0.3	-0.6	-0.1	-1.6	-1.8	-0.4	-0.8	-1.3	0.1	-1.0	0.2	-2.0	0.1	0.0	0.1	-1.4	-1.0	-1.1	-1.8	-1.0	-1.3	-1.6
Depression (self-reported)	1.1	1.3	4.1	-0.3	2.0	1.1	-1.7	-1.7	-1.9	0.1	0.1	-0.1	-0.5	-1.9	0.2	1.4	1.0	1.1	-0.8	-0.2	-1.0	1.6	-0.5	0.7	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	15.7	-0.3	-0.1	0.3	-0.6	-1.1	-4.0	0.9	-0.6	-0.4	0.2	-2.7	-0.7	0.3	0.7	0.9	-1.6	0.3	-1.3	1.3	-0.3	1.8	0.9
Friendships satisfaction	1.1	1.4	5.2	-0.0	0.9	0.5	-2.1	-1.9	-2.3	-1.6	-0.2	-0.3	-1.7	-1.8	-0.5	0.9	1.0	0.7	-1.0	-0.5	-1.6	0.2	-0.2	-0.8	-1.1
Commuting to job workplace: Walk	1.1	1.2	4.8	0.9	1.5	0.3	0.6	0.7	-1.2	2.2	0.3	0.1	1.1	-1.3	0.9	0.4	-0.2	1.1	0.6	1.3	0.8	1.1	1.2	1.7	1.6
Financial situation satisfaction	1.1	1.4	5.5	-0.0	0.3	0.3	-2.3	-2.0	-1.7	-2.3	-0.8	-0.3	-1.4	-1.3	-0.8	0.6	0.2	0.4	-1.2	-0.5	-1.3	-0.5	-0.6	-0.9	-1.5
High cholesterol (Self-reported)	1.1	2.0	8.1	1.3	0.7	-0.7	2.2	1.8	0.2	1.7	0.7	-0.5	2.8	-0.6	1.8	-0.3	-0.9	0.5	1.0	1.4	1.8	0.6	1.7	1.4	2.4
Arm fat-free mass (left)	1.1	5.5	21.4	1.0	4.6	3.4	-2.7	-1.5	-2.1	1.3	2.3	2.6	-1.0	-0.3	1.0	3.9	4.4	3.2	0.4	0.5	-1.3	2.6	1.7	0.5	-0.3
Supplements: Calcium	1.1	1.3	3.8	-0.4	0.4	1.7	-2.0	-1.9	-1.3	-1.5	-0.1	0.6	-1.8	-0.3	-0.3	1.3	0.6	0.6	-1.1	-0.4	-1.4	0.0	-0.9	-0.4	-1.6
Alcohol drinker status: Previous	1.1	1.2	4.3	1.4	1.3	0.7	1.0	0.8	-0.1	0.8	2.0	0.9	2.1	0.6	0.3	0.1	0.5	1.4	1.1	1.3	1.1	0.7	1.2	0.6	1.5
Major Depression (MDD)	1.0	1.2	6.8	0.3	-0.3	-0.4	0.2	-0.2	-2.6	1.7	-0.1	-0.0	1.8	-1.9	-0.2	0.5	-0.5	0.8	-0.8	0.9	0.6	0.6	0.1	1.9	1.4
Crohns Disease (2012)	1.0	1.6	4.0	0.0	0.4	1.3	-0.3	0.9	1.9	1.3	1.1	1.1	0.8	1.6	0.9	0.8	2.0	0.9	1.9	1.0	1.3	1.7	1.3	2.0	0.9
Number of treatments/medications taken	1.0	1.8	10.2	-0.9	1.1	-0.0	1.6	1.7	0.1	1.3	1.5	-0.9	3.2	-0.8	1.1	-0.4	-0.1	-0.4	1.3	0.4	0.7	1.8	0.4	2.4	1.5
Relative age of first facial hair	1.0	2.0	4.6	-1.2	0.2	-0.1	-2.2	-2.1	-1.9	-1.3	-1.1	-0.7	-1.6	-1.2	-2.1	0.7	0.7	-0.2	-2.0	-1.4	-2.0	-0.7	-1.5	-0.7	-1.6
Angina	1.0	1.4	9.5	0.2	-0.0	-0.9	1.5	1.5	1.9	-0.4	1.0	-1.1	3.1	0.2	-0.5	-0.6	-1.8	0.0	1.1	0.7	1.7	-0.4	-0.1	0.5	0.5
Chronic bronchitis/emphysema (father)	1.0	1.2	3.8	0.9	1.9	1.1	-0.2	0.3	-0.7	1.6	0.4	0.8	0.1	-0.1	0.6	1.1	1.9	1.6	0.2	0.8	0.5	1.5	1.6	1.4	1.1
Financial difficulties in last 2 years	1.0	1.3	7.0	-1.0	-0.7	-0.8	-0.9	-1.2	-2.4	-0.6	-1.5	-1.2	-1.0	-2.6	-0.6	-0.4	0.0	-0.8	-1.6	-0.8	-1.5	0.2	-0.7	-0.0	-0.2
Pulse wave Arterial Stiffness index	1.0	1.2	3.9	0.2	2.0	1.3	0.1	0.6	0.9	1.0	0.7	0.5	0.4	0.1	1.5	1.6	1.0	0.9	0.8	0.8	0.8	1.9	1.0	1.7	1.1
Commuting to job workplace: Public transport	1.0	1.2	5.0	0.7	1.0	0.4	0.8	1.0	-0.6	1.8	0.3	0.4	0.5	-0.9	2.2	0.2	0.5	0.5	0.7	1.2	0.8	1.5	1.3	1.7	1.6
Risk taking	1.0	1.4	6.4	0.5	0.6	2.0	-1.6	-1.4	-1.5	0.6	0.2	1.7	-1.4	0.7	0.4	1.8	2.5	1.4	-0.1	0.4	-0.9	0.8	0.5	0.4	-0.5
Arm predicted mass (left)	1.0	5.0	21.7	1.1	4.7	3.2	-2.5	-1.5	-2.1	1.4	2.3	2.6	-0.7	-0.3	0.8	3.7	4.0	3.2	0.4	0.5	-1.2	2.3	1.7	0.4	-0.3
Bipolar Disorder or Schizophrenia	0.9	2.3	7.3	-1.8	-1.4	-0.4	-2.3	-2.4	-2.7	-0.7	-1.7	-1.4	0.2	-1.9	-2.3	1.1	1.0	-0.3	-2.5	-0.7	-1.5	-0.4	-0.8	0.4	0.1
Reaction Time	0.9	1.6	6.5	1.3	0.7	1.5	-1.6	-1.1	-0.6	1.3	0.4	2.1	-1.0	2.2	0.5	2.0	2.5	1.7	0.1	0.0	-0.4	-0.1	1.0	-0.7	-0.6
Blood Eosinophil Count	0.9	7.3	22.3	-3.1	-4.7	-4.5	1.4	0.1	1.5	-2.8	-1.4	-4.5	1.8	-1.1	-3.9	-1.5	-2.9	-3.4	-1.1	-2.3	-0.3	-3.0	-2.9	-2.5	-1.0
Vitamin and mineral supplements	0.9	1.2	3.6	-0.5	-0.7	-1.8	0.5	-0.2	-0.7	0.5	-1.6	-1.5	0.9	-1.9	-1.2	-1.0	-1.9	-1.0	-1.4	-0.6	-0.3	-1.2	-0.9	-0.1	0.5
Average weekly fortified wine intake	0.9	1.0	5.8	-1.0	-0.2	1.1	-1.7	-1.2	0.5	-1.6	-0.8	-0.2	-2.4	0.2	0.1	0.1	1.0	-0.2	-0.7	-0.9	-0.7	0.3	-1.4	-0.1	-1.3
Qualifications: None of the above	0.9	1.8	6.5	0.6	-0.1	-1.2	1.7	1.4	-0.4	2.5	-0.9	-0.7	2.4	-1.6	0.6	0.1	-1.0	-0.0	0.5	1.5	1.7	0.6	1.1	2.1	2.1
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	11.0	-0.2	1.3	0.1	-0.4	-0.6	-3.2	-0.1	-0.1	-0.4	0.4	-3.3	0.4	-0.3	-0.6	0.1	-1.0	0.4	-1.0	1.3	0.4	1.0	1.0
Noisy workplace	0.9	1.1	5.2	-0.4	1.3	0.1	0.3	0.1	-0.9	2.3	0.8	-0.1	1.5	-0.6	0.6	2.1	1.4	0.8	0.2	0.4	0.2	1.2	0.5	1.3	1.1
Angina (self-reported)	0.9	1.2	8.8	0.1	-0.1	-0.8	1.3	1.2	2.0	-0.7	0.9	-1.1	3.0	0.3	-0.6	-0.4	-1.8	-0.0	1.0	0.6	1.6	-0.5	-0.3	0.2	0.2
Medication: Allopurinol	0.9	1.2	4.3	-0.7	-0.7	-0.3	1.2	0.7	-1.2	1.3	0.4	-0.7	1.2	-1.4	1.4	0.2	0.6	-0.6	0.4	0.9	0.5	2.0	0.2	2.1	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.6	0.3	-0.3	-0.6	1.6	1.4	1.8	-0.3	0.1	-1.1	1.8	-0.4	0.5	-0.0	-0.4	-0.1	1.0	1.0	1.9	0.9	0.4	1.3	1.6
Overall health rating	0.9	2.0	8.6	0.5	2.2	0.8	0.0	0.2	-1.1	0.5	1.2	-0.1	1.6	-1.8	0.7	1.7	1.4	1.5	0.5	1.5	0.8	2.9	1.3	2.2	2.1
Illnesses of father: None of the above (group 1)	0.9	1.1	6.7	1.1	-0.7	0.2	-1.1	-1.3	0.1	-1.5	0.1	0.9	-0.8	1.4	-1.1	0.6	-0.5	0.7	-0.0	0.0	-0.3	-1.8	-0.5	-2.6	-1.4
Basal cell carcinoma (self-reported)	0.9	1.1	4.2	-0.3	-0.9	0.0	1.0	1.7	0.7	1.5	0.1	-0.1	1.0	0.3	1.1	-0.0	0.8	-0.2	0.8	0.7	1.1	1.6	1.1	2.0	1.9
Ovarian Cancer	0.8	1.1	5.5	-0.2	0.3	1.4	-1.6	-1.0	0.9	-2.0	0.2	0.6	-2.3	0.9	-0.1	0.7	0.3	0.1	-0.6	-0.6	-0.7	-0.2	-0.7	-1.3	-1.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.5	1.4	1.2	-0.2	0.7	0.3	0.4	0.4	1.7	0.8	1.9	1.1	-0.4	1.2	-0.2	1.4	0.5	0.9	0.7	-0.8	0.9	-0.8	0.4
Sensitivity / hurt feelings	0.8	1.3	4.3	-0.6	-0.3	-1.1	1.8	1.6	-1.0	1.9	0.1	-0.7	1.2	-1.4	0.8	-2.1	-1.5	-0.9	0.5	0.1	0.1	0.7	0.6	1.5	1.5
Pack years adult smoking proportion	0.8	1.2	4.9	0.5	0.6	0.7	-0.5	-0.6	-2.2	1.3	0.7	0.4	1.1	-0.5	-0.4	1.4	1.9	1.8	0.3	1.2	0.1	1.1	0.5	1.5	0.9
Supplements: Glucosamine	0.8	1.0	3.5	0.2	0.3	1.8	-1.1	-0.5	0.9	0.1	0.3	1.4	-1.5	1.9	0.9	1.4	1.8	0.4	0.8	0.3	0.1	0.6	0.1	0.2	-0.9
Exposure to tobacco smoke outside home	0.8	1.1	7.5	0.6	-0.7	-0.3	1.4	1.3	0.4	1.1	1.1	0.3	2.7	0.1	-0.1	-0.2	-1.0	0.5	0.7	1.2	1.4	0.2	0.6	1.1	1.7
Worry too long after embarrassment	0.8	1.3	9.9	-1.5	-0.3	-1.0	-0.3	-0.8	-2.3	0.1	-1.0	-1.5	-0.8	-3.1	0.2	-0.3	-0.2	-0.9	-1.4	-0.9	-1.4	0.6	-0.7	0.1	0.2
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.7	1.4	-1.0	-0.6	1.2	0.6	-0.3	0.7	1.0	0.3	2.2	-0.1	-0.4	0.5	-0.1	1.0	0.8	1.5	1.4	-0.1	1.1	0.5	1.4
Medication for pain relief, constipation, heartburn	0.8	1.4	6.4	-0.6	0.5	0.9	-2.5	-1.6	-1.0	-0.6	-0.7	0.4	-2.5	-0.5	0.1	1.1	1.7	0.4	-1.2	-1.1	-1.7	0.2	-0.6	-0.0	-1.5
Mean time to correctly identify matches	0.8	1.6	5.8	0.7	0.2	1.2	-2.0	-1.6	-1.4	1.3	-0.2	1.7	-1.4	1.7	0.1	2.0	2.4	1.3	-0.5	-0.5	-1.1	-0.4	0.3	-0.6	-1.1
Ever had bowel cancer screening	0.8	0.9	6.3	1.0	-0.4	0.3	0.1	0.3	1.1	-0.9	0.6	1.0	-0.5	2.5	-0.8	-1.0	-0.3	0.2	0.7	-0.0	0.1	-1.4	0.1	-1.6	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	4.8	0.7	-1.0	0.0	1.3	1.1	-0.6	2.2	1.3	0.7	1.1	0.7	0.9	0.8	1.0	0.8	1.2	1.5	1.2	0.9	1.1	1.7	1.8
Medication: Aspirin	0.8	1.0	4.9	-0.0	0.3	-0.4	1.2	1.3	-0.1	1.7	0.5	-0.5	2.2	-0.6	1.2	0.2	0.3	0.1	0.9	0.5	0.9	0.7	0.9	1.8	1.3
Number of self-reported non-cancer illnesses	0.8	1.4	7.2	-0.6	1.3	-0.1	0.6	0.5	-1.5	0.8	0.5	-1.2	1.6	-2.7	0.7	0.7	-0.1	0.3	0.1	0.6	0.1	2.0	0.6	2.1	1.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	5.6	-0.6	-0.4	1.3	-0.1	1.0	1.6	-0.3	1.4	0.7	-0.2	2.4	1.2	0.3	1.5	-0.1	1.9	0.1	0.4	1.1	0.2	1.0	-0.5
Medication: Atorvastatin	0.8	0.9	4.5	0.3	1.0	-0.3	1.3	1.3	-0.1	1.9	0.7	0.1	2.1	0.1	0.6	-0.4	0.7	0.4	0.8	0.5	0.5	0.7	0.8	1.6	1.1
Irritability	0.8	1.4	5.6	-0.7	0.1	-1.4	0.1	-0.9	-2.0	-0.6	-0.7	-1.5	0.8	-2.4	-2.0	-0.7	-1.6	-0.5	-1.6	-0.8	-1.2	-0.9	-1.1	-0.6	-0.3
Impedance of whole body	0.8	4.2	16.1	-0.7	-2.4	-2.9	0.4	-1.0	-0.8	-2.1	-2.6	-2.5	-0.2	-1.9	-2.7	-2.2	-4.0	-1.6	-2.2	-1.2	-0.8	-2.9	-2.0	-2.2	-1.0
Schizophrenia vs Biploar Disorder	0.7	1.0	3.6	1.9	-0.9	-0.1	1.1	0.7	-1.3	1.9	0.8	1.4	0.4	0.9	0.7	0.5	1.5	1.3	-0.4	0.2	-0.3	0.2	0.8	0.6	0.9
Mean Putamen Volume	0.7	0.8	4.1	0.7	-0.4	-0.3	0.6	1.2	1.3	0.4	1.2	0.2	2.0	1.1	-0.4	0.3	0.6	0.6	1.0	0.5	1.0	-0.3	1.1	0.7	0.7
Ulcerative Colitis	0.7	1.0	4.2	0.3	-0.9	0.6	-0.1	0.8	2.0	-0.6	0.2	0.5	0.2	1.7	-0.3	-0.1	0.0	0.2	1.7	1.7	2.0	0.6	1.4	0.4	0.9
Waist Hip Ratio (WHR)	0.7	3.1	26.8	0.4	5.2	2.6	-2.3	-2.8	-0.8	-0.5	-0.6	0.6	-1.5	-0.8	0.0	1.8	0.3	2.1	-1.4	-0.6	-1.2	0.3	-0.8	-1.7	-1.6
Relative age voice broke	0.7	1.0	5.2	-0.4	-0.6	-0.4	-1.3	-1.3	-0.9	-2.3	-0.0	-0.5	-1.6	-0.2	-1.3	0.1	1.1	-0.4	-1.1	-0.8	-1.1	-0.6	-0.7	-1.2	-0.8
Alcohol usually taken with meals	0.7	1.2	4.0	-0.4	-0.6	-1.1	1.0	0.4	1.5	-2.0	0.1	-1.1	-0.1	0.3	-0.9	-1.2	-1.8	-1.1	-0.1	-0.8	0.0	-1.7	-0.8	-2.0	-0.7
Birth weight of first child	0.7	1.3	5.7	1.7	1.4	1.2	-1.0	-0.7	0.3	-1.2	1.2	1.8	-2.1	1.1	0.1	0.4	0.2	1.1	0.7	0.3	-0.1	-0.4	1.0	-2.4	-1.2
Medication: Paracetamol	0.7	1.2	3.1	1.1	1.8	1.0	0.7	0.7	1.5	0.2	1.5	1.0	0.7	1.2	0.5	0.8	0.4	1.0	1.5	1.2	1.4	1.4	1.0	-0.2	1.0
Emphysema/chronic bronchitis	0.7	0.8	2.7	-0.1	1.7	0.9	-0.0	0.0	-1.0	1.6	0.8	0.4	0.8	-0.5	0.4	1.2	1.2	1.0	0.2	0.4	-0.1	1.4	0.6	1.5	0.8
Neck or shoulder pain in last month	0.7	1.0	4.1	-1.2	0.7	0.5	-1.0	-1.6	-1.0	-2.0	-0.0	-1.0	-0.7	-1.6	-0.6	1.2	-0.2	-0.2	-0.8	-0.6	-1.0	0.9	-1.4	-0.7	-0.9
Osteoarthritis (self-reported)	0.7	0.9	4.7	0.2	2.2	1.1	-0.3	-0.0	-1.3	1.1	1.2	0.7	0.0	-0.9	1.1	0.7	1.1	1.0	0.8	0.5	-0.3	1.6	0.9	0.9	0.1
Ever smoked	0.7	1.2	5.3	-0.7	-0.6	0.1	-1.8	-1.5	-2.3	-0.6	-0.8	-0.7	-1.3	-1.8	-0.7	1.1	1.3	0.4	-1.1	-0.6	-1.5	0.3	-0.8	0.3	-0.8
Blood Red Count	0.6	5.8	24.5	1.9	3.1	1.9	2.2	2.6	5.0	0.5	1.5	1.9	-0.9	3.4	4.4	0.4	0.3	0.2	3.0	1.8	3.2	2.4	2.4	-0.4	1.5
Allergy or Eczema	0.6	1.5	6.1	-0.7	-1.1	-2.5	1.3	-0.1	-1.3	-0.5	-0.2	-1.9	1.4	-1.9	-1.1	-0.9	-2.4	-1.3	-0.8	-0.7	-0.5	-1.3	-0.5	-0.9	0.5
Hair Pigment	0.6	16.5	47.5	-0.4	1.3	1.4	-6.9	-6.6	-2.1	-6.6	-2.8	-0.2	-6.2	-0.6	-4.5	2.7	1.1	0.9	-4.1	-3.4	-4.5	-3.1	-3.1	-6.3	-6.2
Ever had hysterectomy (womb removed)	0.6	0.7	6.2	-0.3	0.3	0.0	0.7	1.2	2.5	-0.6	0.1	-0.5	1.2	1.3	0.3	-0.4	-0.7	-0.4	1.1	0.4	1.3	-0.1	-0.3	0.1	0.2
Supplements: Zinc	0.6	0.7	2.8	0.2	-0.8	1.0	-1.0	-1.0	-1.7	0.3	1.0	0.9	-1.5	0.4	0.3	1.2	1.2	0.8	0.0	0.1	-0.8	0.2	0.0	-0.1	-0.6
Qualifications: CSEs or equivalent	0.6	0.8	2.7	1.7	-0.2	-0.0	0.8	0.7	-0.2	0.1	1.2	0.8	1.4	0.2	-0.3	-0.1	-0.3	1.1	0.9	1.6	1.2	0.1	1.0	0.6	1.1
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.2	1.4	1.4	0.7	0.4	0.2	0.0	0.5	1.1	0.8	0.4	-0.1	0.0	1.1	0.0	1.5	0.5	1.2	0.8	0.9	1.2	0.0	0.7
Number of full brothers	0.6	0.7	4.0	-0.9	-1.1	-0.1	-0.3	-0.5	-2.0	0.6	-0.9	-0.7	-0.5	-1.0	0.3	0.9	0.9	-0.3	-1.2	-0.2	-0.8	0.4	-0.5	1.6	0.5
Age at first live birth	0.6	1.1	4.1	0.5	1.7	2.0	-0.8	0.1	1.6	-1.0	0.6	1.1	-1.6	1.4	1.5	0.4	0.9	0.5	0.8	0.4	0.6	1.2	0.3	0.2	-0.3
Health satisfaction	0.6	0.8	4.8	0.1	0.5	-0.6	0.4	0.1	-2.2	0.4	1.0	-0.7	1.6	-1.8	0.2	0.9	-0.1	0.5	0.3	0.5	-0.3	0.7	0.7	1.0	0.6
Heart disease (mother)	0.6	0.8	3.1	-1.1	-0.7	-1.8	0.5	-0.1	-0.8	0.6	-0.9	-1.5	0.7	-1.1	-0.1	-0.5	-0.8	-1.1	-0.9	-1.0	-0.8	-1.0	-0.5	-0.2	-0.1
Medication: Aspirin	0.6	0.8	5.0	-0.2	-0.2	-0.6	0.9	1.0	-0.1	1.2	0.2	-0.9	2.2	-0.8	0.8	0.3	-0.0	0.0	0.7	0.6	1.0	0.6	0.4	1.8	1.2
Back pain experienced in last month	0.6	0.8	5.1	-1.2	-0.7	-1.0	0.1	-0.1	-1.1	-0.9	-0.7	-1.9	-0.0	-2.2	-0.3	-0.5	-1.2	-1.2	-0.2	-0.4	-0.5	0.3	-0.6	-0.6	0.1
Number of operations (self-reported)	0.6	0.9	4.5	0.7	0.6	1.3	-1.1	-0.4	1.4	-1.6	0.4	1.1	-0.6	2.1	-0.6	0.6	-0.2	0.7	0.7	0.2	0.2	-0.9	-0.4	-1.0	-1.6
Schizophrenia (2018)	0.5	1.0	4.4	0.0	-0.4	0.1	-0.1	-0.1	-1.6	2.1	-0.2	0.1	1.6	-0.6	-0.0	0.8	1.6	0.7	-0.9	0.1	-0.3	0.8	0.5	1.8	1.4
Alzheimer’s Disease (in father)	0.5	0.5	2.7	0.4	0.6	-0.1	-0.9	-1.1	-0.5	-1.6	0.7	-0.2	-0.6	-0.4	-0.9	0.5	-0.1	0.7	-0.2	-0.1	-0.4	-0.6	-0.5	-1.6	-0.6
HbA1C	0.5	0.6	1.8	-0.9	0.1	0.3	-0.9	-1.4	-0.8	-1.1	0.4	-0.3	-1.1	-0.9	0.5	1.0	0.1	-0.4	-0.9	-0.6	-0.9	0.2	-1.2	-0.4	-0.6
Rheumatoid Arthritis	0.5	0.7	4.2	0.1	-0.5	0.8	0.5	0.7	2.0	-0.3	0.6	0.6	0.2	1.9	0.3	-0.5	-1.2	-0.2	1.3	0.5	1.0	-0.6	-0.3	-0.2	-0.4
Schizophrenia (2014)	0.5	1.2	4.9	0.5	-0.5	0.4	-1.1	-1.3	-2.2	1.1	-0.3	0.5	0.8	-0.6	-0.9	1.9	1.8	1.5	-1.5	0.5	-0.3	0.5	0.4	1.0	1.0
Average weekly spirits intake	0.5	0.6	3.2	-0.3	1.4	0.9	-0.6	0.2	1.0	0.7	-0.1	0.1	-0.4	0.2	1.8	0.8	1.6	0.2	0.3	-0.3	0.1	1.3	0.4	0.5	0.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	3.6	0.5	1.9	1.1	-0.0	0.3	1.4	-0.7	0.7	0.4	0.5	1.3	-0.5	0.5	0.6	0.9	0.6	0.4	0.6	0.3	0.2	-0.5	-0.4
Number of incorrect matches in round	0.5	0.8	6.1	0.4	0.1	0.3	-0.1	0.0	2.4	0.1	-0.2	0.7	-0.5	2.5	0.0	0.4	0.4	0.1	0.7	-0.1	0.8	-1.1	-0.2	-1.4	-0.7
Past tobacco smoking	0.5	1.0	5.8	-0.3	-0.5	-1.2	1.0	0.5	1.2	-0.7	-0.7	-0.6	0.4	0.4	-0.3	-1.8	-2.4	-1.4	-0.4	-0.6	0.3	-1.5	-0.4	-1.2	-0.2
Had menopause	0.5	0.6	2.1	0.4	1.2	1.2	-1.4	-0.7	0.0	-0.7	0.2	0.6	-1.0	0.4	-0.1	1.4	1.1	1.1	0.2	0.1	-0.3	0.4	0.2	-0.1	-1.2
Allergy	0.5	1.2	3.8	0.4	-0.0	1.9	-0.8	0.2	1.4	0.6	0.1	1.8	-1.3	1.9	1.3	0.1	1.7	0.5	1.2	0.7	0.8	1.4	0.3	0.9	-0.1
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	5.2	-0.2	0.1	-0.7	0.9	0.5	1.0	-0.8	-0.3	-1.0	0.8	-1.0	-0.5	-1.0	-2.3	-0.5	-0.2	-0.1	0.4	-0.6	-0.3	-0.2	0.2
Medication: Lansoprazole	0.5	0.6	1.8	-0.5	-0.7	-0.6	0.3	0.0	0.4	-1.0	-0.7	-1.0	0.8	-0.3	-1.2	-1.2	-1.4	-0.5	-0.5	-0.6	-0.1	-0.9	-0.9	-0.2	-0.4
Pulse wave reflection index	0.5	0.7	2.6	-0.4	-0.7	-0.9	1.6	1.3	1.0	1.2	-0.6	-0.6	0.7	-0.1	0.7	-0.8	-0.7	-0.9	0.4	0.1	0.8	0.2	0.3	0.9	1.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.0	1.1	0.7	0.8	-0.2	-0.1	-0.2	0.4	1.0	0.8	0.4	0.3	0.4	1.7	1.0	1.3	0.5	0.9	0.5	0.7	1.1	0.5	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	3.9	-0.0	0.2	0.4	-1.4	-1.1	-2.0	-0.6	0.1	-0.1	-0.5	-1.0	-0.7	0.4	1.2	0.6	-0.4	-0.2	-1.2	0.6	0.2	-0.1	-0.4
Wheeze or whistling in the chest in last year	0.5	0.9	2.7	1.0	1.2	0.1	0.6	0.5	0.2	0.4	1.2	0.0	1.7	-0.8	0.1	1.6	0.1	1.5	0.2	1.1	0.9	0.9	1.1	0.2	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.8	0.6	0.4	0.6	-0.3	0.4	-0.3	0.9	-0.0	0.5	0.3	-0.1	0.5	0.3	1.4	0.9	0.6	0.7	0.3	1.2	0.9	1.7	0.6
Leg pain on walking	0.5	0.7	3.1	-0.4	0.8	-0.1	-1.0	-0.9	-1.7	-0.1	0.2	-0.7	0.2	-1.7	-0.3	1.8	0.5	0.8	-0.8	0.0	-0.6	0.7	-0.2	0.5	-0.0
Illnesses of father: Heart disease	0.5	0.6	3.9	0.1	1.7	0.6	0.4	0.2	-0.8	0.9	0.8	0.3	0.7	-0.5	0.5	0.4	0.5	0.8	0.0	0.5	0.2	1.0	0.7	2.0	0.7
Smoking status: Previous	0.5	0.8	4.0	0.4	0.5	1.1	-0.1	0.4	0.2	1.2	1.0	0.9	0.3	0.9	0.5	1.1	2.0	1.2	1.0	0.7	0.3	1.1	0.6	1.0	0.4
Mineral and other dietary supplements	0.5	0.7	3.4	-0.1	0.8	-0.7	-0.4	-1.0	-1.6	0.7	-0.8	-0.7	0.4	-1.8	-1.0	-0.1	-0.2	0.2	-1.5	-0.5	-0.8	-0.6	-0.4	-0.1	0.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.3	-0.8	-0.4	-0.3	-0.1	-0.4	1.3	-1.5	-0.4	-0.7	-0.1	0.7	-1.3	-0.9	-0.3	-0.8	-0.6	-0.7	0.0	-0.8	-1.1	-1.4	-0.5
Crohns Disease (2017)	0.4	0.8	4.4	-0.4	0.1	0.8	-0.4	0.6	0.6	1.2	0.4	0.5	1.1	0.6	1.0	0.7	1.4	0.3	0.9	0.5	0.6	1.7	0.5	2.1	0.8
Coronary Artery Disease (CAD)	0.4	0.5	4.1	-0.4	0.0	-0.2	1.1	1.0	0.6	0.4	0.6	-0.6	2.0	-0.1	0.1	0.3	0.1	-0.3	0.7	0.5	0.9	0.3	-0.1	1.1	0.7
Respiratory disease	0.4	1.0	3.5	0.1	1.7	0.2	0.6	0.5	-0.7	1.2	0.1	-0.6	1.1	-1.9	1.2	1.2	-0.3	0.5	-0.3	0.6	0.3	1.5	0.9	1.5	1.5
Tanning	0.4	5.5	24.6	-1.9	-3.1	-2.3	-1.7	-2.7	-5.0	-0.8	-2.3	-1.8	-1.7	-3.6	-2.5	0.1	-0.4	-1.4	-3.2	-2.0	-3.5	-1.8	-1.4	-1.2	-1.3
Serious illness, injury or assault to yourself	0.4	0.4	2.2	0.2	-0.2	0.4	-0.6	-0.1	0.8	-1.5	1.1	0.3	1.0	1.1	-0.9	0.8	0.3	0.5	0.2	0.4	0.4	-0.5	-0.2	-0.3	-0.3
Multivitamins +/- minerals	0.4	0.5	2.1	-0.0	0.6	1.1	-0.5	-0.2	-0.4	-0.4	1.3	0.7	-1.1	0.3	1.5	0.6	0.9	0.4	0.9	0.2	-0.3	1.1	0.5	0.1	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	1.0	4.6	-0.0	0.3	0.5	-0.9	-0.8	-0.0	-1.4	-1.6	0.0	-2.1	-0.1	-0.4	-1.1	-0.9	-0.5	-0.9	-0.9	-1.0	-1.0	-0.7	-1.4	-1.4
Mouth/teeth dental problems: Dentures	0.4	0.6	3.0	0.7	0.4	-0.2	-0.7	-1.1	-0.5	-0.6	-0.8	0.1	-1.0	-0.3	-1.4	0.0	-0.6	0.7	-0.7	-0.4	-0.5	-1.1	-0.4	-1.7	-0.9
Asthma	0.4	0.8	5.2	-1.3	0.3	-0.6	0.0	0.3	-0.5	-0.3	-0.8	-2.0	0.9	-2.3	-0.1	0.3	-0.7	-0.6	-1.1	-0.6	-0.6	0.5	-0.4	1.2	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.6	1.0	0.0	0.2	0.4	0.0	0.4	-1.6	0.4	0.1	-0.7	0.5	-0.1	-0.4	-1.6	-0.0	0.3	0.6	0.5	-0.3	0.0	-1.4	0.2
Impedance of arm (left)	0.4	2.0	5.2	1.9	0.8	0.4	1.9	1.7	1.7	1.5	1.0	1.3	1.4	2.1	0.9	-0.4	-0.6	1.2	1.5	1.9	2.3	0.3	1.5	0.9	1.7
Medication: Ibuprofen	0.4	0.4	1.4	0.8	0.1	0.2	0.9	0.5	0.3	-0.9	1.1	0.4	-0.4	0.8	0.1	-0.9	-1.2	0.0	0.8	0.7	0.5	-0.2	0.4	-1.0	0.3
Family relationship satisfaction	0.4	0.5	3.5	0.9	0.6	0.2	-0.7	-0.8	-1.9	-0.2	0.4	0.3	-0.5	-1.2	0.2	0.8	0.4	1.0	-0.3	0.4	-0.6	-0.0	0.9	-0.2	0.0
Handedness (chirality/laterality): Left-handed	0.4	0.4	3.7	0.1	-0.8	-0.8	0.7	-0.0	-1.9	0.3	0.4	-0.0	0.2	-0.7	-0.4	-1.2	-0.5	-0.1	-0.7	0.0	-0.6	-0.5	0.0	-0.0	0.1
Asthma (self-reported)	0.4	0.8	5.2	-1.2	0.5	-0.4	-0.1	0.2	-0.5	-0.2	-0.7	-1.8	0.8	-2.3	0.1	0.5	-0.6	-0.5	-1.0	-0.6	-0.5	0.6	-0.3	1.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.7	3.5	-0.4	-1.9	-0.8	-0.1	-0.5	0.4	-0.9	-0.8	-0.1	-1.7	0.6	-0.2	-0.4	-0.8	-1.1	-0.6	-0.4	-0.3	-0.9	-1.2	-1.2	-0.8
Ever depressed for a whole week	0.4	0.5	3.2	0.6	1.0	0.6	-0.1	-0.4	-1.8	0.6	0.9	0.9	0.3	-0.3	0.3	0.5	1.1	0.9	-0.2	0.6	-0.5	0.8	0.4	0.7	0.7
Commuting to job workplace: Cycle	0.4	0.5	2.1	-0.8	-1.1	-0.5	0.2	0.8	0.7	-0.3	-0.9	-0.8	-0.5	-0.1	1.1	-1.1	0.1	-1.5	0.3	-0.6	0.0	0.4	-0.2	0.2	0.1
Irritable Bowel Disease (IBD)	0.3	0.6	1.8	0.4	-0.1	1.1	-0.7	0.3	0.9	0.5	0.1	0.9	0.6	1.1	0.6	1.0	1.1	0.7	0.7	0.7	0.7	1.3	0.7	1.1	0.4
Ulcerative Colitis (UC)	0.3	0.6	1.8	1.1	-0.5	0.8	0.1	0.7	0.9	0.7	0.1	1.3	0.4	1.3	0.4	0.6	0.3	0.8	0.7	1.1	1.0	0.7	1.1	0.5	0.7
Lung FEV1/FVC ratio	0.3	1.4	4.6	-0.9	-1.7	-1.6	0.3	0.3	0.2	-1.5	-1.1	-1.2	-0.9	0.0	-0.7	-2.1	-1.2	-2.1	-0.5	-1.1	-0.7	-1.7	-0.8	-1.6	-0.8
Hearing difficulty/problems: Yes	0.3	0.5	1.9	-0.1	0.2	1.1	-1.0	-1.4	-0.4	-0.9	0.1	0.0	-0.9	0.1	-1.0	1.3	0.1	0.6	-0.5	0.1	-0.3	0.0	-0.9	-0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.0	-0.5	-0.8	-0.8	-0.0	0.3	-1.0	-0.5	0.6	-1.0	0.3	-0.8	0.0	0.1	0.2	-0.1	0.4	0.0	-0.4	0.7	0.1	0.2	0.5
Had other major operations	0.3	0.4	2.2	0.4	1.1	0.4	-0.5	-0.3	0.8	-0.4	0.0	0.4	-0.8	0.5	-0.6	0.3	-0.8	0.3	0.4	-0.2	-0.1	0.0	0.0	-1.5	-0.7
Happiness	0.3	0.3	1.4	-0.1	0.6	0.5	-0.5	0.0	-1.0	-0.3	0.3	-0.2	-0.5	-0.9	1.0	-0.3	0.3	0.2	0.3	0.1	-0.2	0.8	0.4	1.2	0.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.4	0.6	1.6	0.7	0.2	0.3	1.0	-0.5	0.8	0.9	-0.4	0.8	0.3	-0.8	-0.6	0.6	0.5	0.0	0.1	0.0	0.3	-0.7	-0.1
Gout (self-reported)	0.3	0.5	2.3	-0.4	0.1	-0.6	0.6	0.1	-1.1	0.9	0.0	-0.8	1.0	-1.5	0.7	0.1	-0.2	-0.2	-0.1	0.2	0.1	0.8	-0.0	0.9	1.1
Number of children fathered	0.3	0.4	2.7	0.4	-0.5	-0.1	0.7	0.7	1.1	0.4	0.6	0.4	0.8	1.6	-0.3	0.4	0.2	0.2	0.7	0.1	0.5	-0.4	0.3	-0.3	-0.3
Number of full sisters	0.3	0.4	2.0	-0.8	-1.4	-0.9	0.3	0.3	-1.2	-0.0	0.2	-0.7	0.4	-0.5	0.8	0.2	0.0	-1.1	0.3	-0.2	-0.5	0.4	-0.3	0.1	0.5
Average weekly red wine intake	0.3	0.5	2.6	-0.4	-1.3	-0.3	0.3	0.2	-1.0	-1.1	0.6	-0.4	-1.6	-0.2	0.6	-0.8	0.4	-1.0	0.3	-0.3	-0.8	0.3	0.0	-0.3	-0.3
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	-0.9	0.6	0.1	-0.7	-0.4	-0.8	-0.6	-0.6	-0.8	0.1	-1.1	0.3	0.6	1.0	-0.4	-0.1	-0.2	-0.5	1.2	-0.1	0.5	0.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.7	-0.2	0.0	1.2	-1.0	-0.0	0.0	-0.4	-0.3	0.5	-0.9	0.4	0.5	-0.1	1.0	0.3	0.0	0.1	-0.1	0.4	0.0	1.3	-0.4
Heart disease (siblings)	0.3	0.4	1.3	0.0	0.9	0.3	-1.2	-0.8	-0.5	0.3	-0.5	0.1	-0.4	0.1	-1.0	0.7	0.6	0.9	-0.9	-0.5	-0.6	-0.7	-0.3	-0.1	-0.8
Medication: Co-codamol	0.2	0.2	2.0	0.3	0.3	-0.3	0.1	0.1	0.5	-0.5	-0.0	-0.3	1.0	0.1	-1.4	-0.3	-0.1	0.2	0.2	0.3	0.6	-0.0	-0.1	-0.1	0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.3	-0.2	-0.3	-0.2	1.0	0.7	0.2	0.7	0.1	-0.3	0.9	-0.3	-0.1	-0.5	-0.5	-0.0	0.2	0.5	0.6	0.3	-0.0	1.1	0.7
Number of live births	0.2	0.2	1.3	0.1	-0.5	-0.5	0.7	0.2	0.3	1.0	-0.4	-0.3	0.4	-0.3	0.7	1.1	0.3	-0.0	0.1	0.3	0.6	0.3	0.2	0.5	0.4
Qualifications: College or University degree	0.2	0.7	2.7	-0.2	0.4	1.7	-1.0	-0.4	1.0	-1.5	0.3	0.4	-1.6	0.9	1.0	0.8	1.2	-0.0	0.4	0.2	-0.0	1.3	-0.4	0.4	-0.3
Medication: Omeprazole	0.2	0.3	1.3	-0.4	0.1	0.1	-0.2	-0.3	0.9	-1.2	0.1	-0.1	-0.4	0.8	-0.7	-0.7	0.3	-0.4	-0.1	-0.4	-0.0	-0.4	-0.5	-1.0	-0.4
Had major operations	0.2	0.2	1.3	-0.2	-0.1	0.3	-0.4	-0.3	-0.9	-1.2	-0.1	-0.3	0.1	-0.7	0.0	0.0	-0.2	0.0	0.1	0.3	-0.2	0.2	-0.4	0.5	-0.4
Wears glasses or contact lenses	0.2	0.3	1.5	-0.2	0.8	0.1	-0.3	0.4	-0.5	0.8	-0.5	-0.2	0.3	-0.4	0.6	0.1	1.0	0.1	-0.1	-0.2	-0.2	0.5	0.4	1.2	0.1
Age started oral contraceptive pill	0.2	0.2	1.5	-0.1	-0.3	-0.1	0.1	0.2	0.7	0.3	-1.2	0.1	-0.3	0.4	0.3	-0.8	-1.1	-0.6	-0.3	-0.3	0.0	-0.4	-0.1	-0.2	-0.3
Age at First Birth	0.1	0.2	0.7	-0.1	0.5	0.0	0.5	0.5	0.5	0.6	-0.8	-0.4	0.5	-0.3	0.4	-0.1	-0.2	-0.2	-0.1	0.2	0.8	0.5	0.2	0.7	0.5
Impedance of arm (right)	0.1	0.6	1.8	0.8	-0.3	-0.4	1.2	1.0	0.9	0.8	0.2	0.4	0.8	1.3	-0.0	-1.0	-1.0	0.2	0.5	0.7	1.2	-0.4	0.5	0.2	0.8
Breast cancer (self-reported)	0.1	0.1	1.1	0.0	0.4	-0.1	-0.0	-0.0	1.0	-0.4	-0.5	0.2	-0.1	0.4	-0.3	0.0	0.1	-0.3	-0.5	-0.2	0.1	-0.1	0.0	-0.5	-0.1
Osteoporosis (self-reported)	0.1	0.2	1.2	0.2	-0.1	0.0	0.6	-0.1	0.2	-0.6	0.1	0.1	-0.5	-0.5	0.2	-0.7	-1.1	-0.2	0.1	0.4	0.2	0.3	-0.1	-0.0	0.2

Hub : Genes

MADD

Models

Trait associations