[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr1:107,418,424-109,188,382

Best TWAS P=1.45e-50 · Best GWAS P=7.7e-51 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex VAV3 0.09 0.03 enet 24 0.05 1.1e-06 -2.3 5.2 2.0e-07 0.36 0.34 0.31 FALSE
2 GTEx Lung VAV3 0.25 0.23 lasso 2 0.23 2.4e-17 13.7 13.6 3.4e-42 0.90 0.98 0.02 FALSE
3 GTEx Nerve Tibial VAV3 0.20 0.07 lasso 5 0.09 8.8e-07 9.9 9.3 1.5e-20 0.77 0.13 0.86 FALSE
4 GTEx Thyroid VAV3 0.36 0.27 lasso 5 0.29 2.7e-22 15.0 15.0 1.5e-50 1.00 0.00 1.00 TRUE
5 NTR Blood VAV3 0.03 0.01 lasso 4 0.01 3.6e-03 13.7 13.2 6.7e-40 0.82 0.10 0.72 FALSE
6 The Cancer Genome Atlas Thyroid Carcinoma VAV3 0.09 0.02 enet 13 0.05 1.3e-05 13.9 12.7 6.6e-37 0.87 0.01 0.99 FALSE