TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Hypothyroidism (self reported)
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chr17:6,190,353-7,949,434
Best TWAS P=2.24e-08 · Best GWAS P=1.01e-13 conditioned to 3.7e-07
6.2M
6.4M
6.6M
6.8M
7M
7.2M
7.4M
7.6M
7.8M
8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
ACAP1
0.33
0.21
enet
34
0.29
1.1e-96
7.4
-5.6
2.2e-08
-0.85
0.00
1.00
TRUE
1
GTEx
Testis
RP11-589P10.7
0.28
0.00
lasso
5
0.00
2.0e-01
5.8
-5.5
4.3e-08
-0.52
0.05
0.35
FALSE