[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr19:4,118,871-5,529,588

Best TWAS P=9.98e-13 · Best GWAS P=1.45e-23 conditioned to 4.83e-09

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	ROSMAP	Brain Pre-frontal Cortex	TICAM1	0.07	0.02	lasso	5	0.04	1.2e-05	8.7	7.1	1.0e-12	0.81	0.01	0.99	TRUE
2	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FEM1A	0.06	0.00	blup	42	0.03	1.4e-04	8.1	-6.3	3.9e-10	-0.53	0.01	0.43	TRUE
5	The Cancer Genome Atlas	Thyroid Carcinoma	TICAM1	0.07	0.04	blup	54	0.06	1.6e-06	8.1	6.9	4.6e-12	0.78	0.01	0.99	FALSE
3	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FEM1A	0.10	0.10	lasso	3	0.08	4.6e-04	-6.8	-6.7	1.8e-11	-0.66	0.03	0.46	FALSE
4	The Cancer Genome Atlas	Prostate Adenocarcinoma	FEM1A	0.03	0.01	enet	6	0.02	5.0e-03	-4.0	-6.4	1.6e-10	-0.73	0.05	0.36	FALSE