Best TWAS P=2.39e-10 · Best GWAS P=3.47e-10 conditioned to 0.287
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | NDFIP1 | 0.20 | 0.10 | lasso | 9 | 0.12 | 3.8e-12 | -6.2 | 6.3 | 2.4e-10 | -0.93 | 0.01 | 0.99 | TRUE |
2 | METSIM | Adipose | NDFIP1 | 0.23 | 0.15 | lasso | 8 | 0.16 | 7.1e-23 | -5.4 | -5.6 | 1.9e-08 | 0.73 | 0.42 | 0.57 | FALSE |