[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr5:149,577,574-151,024,052

Best TWAS P=1.05e-16 · Best GWAS P=5.19e-16 conditioned to 0.019

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF300P1	0.36	0.18	lasso	6	0.36	9.5e-46	7.9	5.5	4.0e-08	0.77	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	ZNF300P1	0.64	0.54	lasso	9	0.63	5.3e-66	7.6	7.7	1.5e-14	0.95	0.07	0.93	FALSE
3	GTEx	Adipose Visceral Omentum	ZNF300P1	0.67	0.43	enet	12	0.54	5.2e-33	7.9	7.8	6.1e-15	0.96	0.03	0.97	FALSE
4	GTEx	Adrenal Gland	ZNF300P1	0.53	0.15	enet	16	0.14	1.0e-05	7.9	7.0	3.6e-12	0.90	0.02	0.98	FALSE
5	GTEx	Artery Coronary	ZNF300P1	0.73	0.71	lasso	3	0.70	5.9e-32	7.9	7.9	3.2e-15	0.93	0.02	0.98	FALSE
6	GTEx	Artery Tibial	ZNF300P1	0.66	0.65	enet	14	0.69	1.5e-74	7.9	7.8	6.1e-15	0.95	0.02	0.98	FALSE
7	GTEx	Brain Cerebellar Hemisphere	ZNF300P1	0.72	0.55	lasso	8	0.52	9.1e-16	7.9	7.6	3.9e-14	0.92	0.02	0.98	FALSE
8	GTEx	Brain Cortex	ZNF300P1	0.41	0.15	lasso	4	0.31	2.7e-09	7.6	5.4	5.3e-08	0.75	0.06	0.86	FALSE
9	GTEx	Brain Frontal Cortex BA9	ZNF300P1	0.34	0.15	enet	22	0.32	4.4e-09	7.9	5.6	2.1e-08	0.77	0.02	0.96	FALSE
10	GTEx	Brain Hypothalamus	ZNF300P1	0.68	0.24	lasso	16	0.35	4.1e-09	7.9	5.2	2.0e-07	0.76	0.02	0.95	FALSE
11	GTEx	Brain Putamen basal ganglia	ZNF300P1	0.44	0.28	lasso	4	0.34	4.9e-09	7.6	6.5	1.1e-10	0.86	0.03	0.97	FALSE
12	GTEx	Breast Mammary Tissue	ZNF300P1	0.49	0.39	enet	20	0.47	7.7e-27	7.6	7.7	1.4e-14	0.94	0.08	0.92	FALSE
13	GTEx	Breast Mammary Tissue (Male)	ZNF300P1	0.36	0.24	lasso	3	0.21	1.1e-05	7.6	7.4	1.4e-13	0.91	0.05	0.89	FALSE
14	GTEx	Breast Mammary Tissue (Female)	ZNF300P1	0.66	0.33	enet	22	0.44	1.1e-14	7.9	7.2	4.3e-13	0.90	0.03	0.97	FALSE
15	GTEx	Colon Sigmoid	ZNF300P1	0.65	0.34	enet	24	0.50	3.4e-20	7.6	6.9	4.5e-12	0.88	0.09	0.91	FALSE
16	GTEx	Colon Transverse	ZNF300P1	0.51	0.41	enet	8	0.47	9.2e-25	7.6	7.6	3.2e-14	0.95	0.19	0.81	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	ZNF300P1	0.74	0.64	lasso	4	0.69	2.7e-33	7.9	7.8	6.8e-15	0.95	0.04	0.96	FALSE
18	GTEx	Esophagus Mucosa	ZNF300P1	0.55	0.44	enet	20	0.50	4.0e-38	7.6	7.4	1.2e-13	0.94	0.18	0.82	FALSE
19	GTEx	Esophagus Muscularis	ZNF300	0.10	0.10	enet	12	0.10	9.6e-07	8.0	6.9	6.1e-12	0.88	0.02	0.98	FALSE
20	GTEx	Esophagus Muscularis	ZNF300P1	0.61	0.61	enet	17	0.62	9.7e-48	7.6	7.7	1.0e-14	0.94	0.10	0.90	FALSE
21	GTEx	Heart Atrial Appendage	ZNF300P1	0.61	0.39	enet	19	0.47	2.0e-23	7.9	7.4	1.7e-13	0.95	0.04	0.96	FALSE
22	GTEx	Heart Left Ventricle	ZNF300P1	0.53	0.47	enet	20	0.51	3.3e-31	7.6	7.8	8.8e-15	0.91	0.08	0.92	FALSE
23	GTEx	Liver	ZNF300P1	0.32	0.18	lasso	4	0.15	7.3e-05	7.6	7.6	2.3e-14	0.95	0.03	0.97	FALSE
24	GTEx	Lung	ZNF300P1	0.57	0.46	lasso	8	0.58	8.1e-54	7.6	7.7	1.2e-14	0.95	0.08	0.92	FALSE
25	GTEx	Muscle Skeletal	ZNF300P1	0.49	0.41	enet	20	0.51	2.9e-58	7.9	8.0	1.2e-15	0.94	0.02	0.98	FALSE
26	GTEx	Nerve Tibial	ZNF300P1	0.70	0.63	lasso	4	0.70	5.8e-68	7.6	7.7	1.6e-14	0.95	0.19	0.81	FALSE
27	GTEx	Ovary	ZNF300P1	0.36	0.12	lasso	5	0.11	1.2e-03	7.6	8.0	1.6e-15	0.96	0.02	0.94	FALSE
28	GTEx	Pancreas	ZNF300P1	0.58	0.60	lasso	4	0.60	7.6e-31	7.9	7.8	6.6e-15	0.95	0.02	0.98	FALSE
29	GTEx	Pituitary	ZNF300P1	0.72	0.41	lasso	14	0.46	4.1e-13	7.6	7.4	1.3e-13	0.92	0.03	0.97	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	ZNF300P1	0.53	0.49	lasso	5	0.50	7.4e-31	7.6	7.6	3.2e-14	0.94	0.19	0.81	FALSE
31	GTEx	Skin Sun Exposed Lower leg	ZNF300P1	0.44	0.44	lasso	3	0.46	1.3e-41	7.9	7.5	5.3e-14	0.93	0.02	0.98	FALSE
32	GTEx	Spleen	ZNF300P1	0.69	0.50	lasso	7	0.47	9.8e-14	7.6	7.5	8.1e-14	0.93	0.07	0.92	FALSE
33	GTEx	Stomach	ZNF300P1	0.57	0.41	enet	31	0.48	7.4e-26	7.6	7.8	6.2e-15	0.90	0.12	0.88	FALSE
34	GTEx	Testis	ZNF300	0.28	0.18	lasso	6	0.18	2.1e-08	7.9	7.7	2.0e-14	0.91	0.01	0.99	FALSE
35	GTEx	Thyroid	ZNF300P1	0.57	0.58	lasso	9	0.60	7.8e-57	7.9	7.8	5.4e-15	0.94	0.02	0.98	FALSE
36	GTEx	Vagina	ZNF300P1	0.61	0.17	lasso	11	0.27	6.2e-07	7.6	8.2	2.6e-16	0.96	0.03	0.97	FALSE
37	ROSMAP	Brain Pre-frontal Cortex	ZNF300P1	0.36	0.31	bslmm	516	0.48	2.8e-69	7.9	5.8	7.7e-09	0.85	0.01	0.99	FALSE
38	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LOC134466	0.13	0.09	lasso	4	0.09	8.0e-08	7.6	7.8	5.7e-15	0.96	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Breast Invasive Carcinoma	DCTN4	0.10	0.02	enet	11	0.03	1.9e-07	6.6	7.8	8.6e-15	0.77	0.00	1.00	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DCTN4	0.18	0.03	blup	51	0.03	1.8e-04	6.6	8.3	1.1e-16	0.81	0.00	0.99	TRUE
41	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IRGM	0.17	0.09	lasso	4	0.08	1.2e-09	8.0	8.0	1.8e-15	0.93	0.01	0.99	FALSE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF300	0.05	0.04	lasso	2	0.03	9.3e-05	7.9	7.9	3.9e-15	0.92	0.02	0.98	FALSE
43	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC134466	0.12	0.09	lasso	5	0.08	2.0e-04	7.9	7.6	3.2e-14	0.93	0.01	0.94	FALSE
44	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC134466	0.10	0.05	enet	7	0.05	2.1e-06	7.9	6.7	1.7e-11	0.88	0.00	1.00	FALSE
45	The Cancer Genome Atlas	Rectum Adenocarcinoma	DCTN4	0.83	-0.01	lasso	16	0.08	6.8e-03	6.5	6.8	7.5e-12	0.60	0.00	0.42	FALSE
46	The Cancer Genome Atlas	Soft Tissue Sarcoma	IRGM	0.08	0.05	lasso	8	0.05	5.3e-04	7.8	7.8	4.8e-15	0.93	0.02	0.92	FALSE
47	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LOC134466	0.43	0.04	enet	15	0.08	7.2e-04	7.9	7.3	2.4e-13	0.91	0.01	0.95	FALSE
48	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF300	0.03	0.01	blup	45	0.01	8.1e-02	6.7	7.6	3.7e-14	0.86	0.02	0.43	FALSE