Best TWAS P=3.96e-09 · Best GWAS P=5.54e-09 conditioned to 5.05e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GIGYF1 | 0.14 | 0.10 | enet | 22 | 0.14 | 1.9e-11 | 3.2 | 5.2 | 1.5e-07 | -0.07 | 0.06 | 0.87 | FALSE |
| 2 | GTEx | Esophagus Mucosa | GIGYF1 | 0.10 | 0.01 | enet | 15 | 0.07 | 1.0e-05 | 3.2 | 5.2 | 2.5e-07 | -0.05 | 0.10 | 0.65 | FALSE |
| 3 | GTEx | Muscle Skeletal | GIGYF1 | 0.10 | 0.03 | enet | 14 | 0.06 | 6.8e-07 | 3.2 | 5.9 | 4.0e-09 | -0.07 | 0.04 | 0.91 | TRUE |
| 4 | GTEx | Thyroid | ARPC1B | 0.36 | 0.10 | lasso | 8 | 0.13 | 4.2e-10 | 5.2 | 5.2 | 1.9e-07 | 0.27 | 0.05 | 0.95 | TRUE |