[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr7:106,847,492-108,340,749

Best TWAS P=9.51e-14 · Best GWAS P=8.21e-16 conditioned to 0.000551

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLD 0.17 0.14 bslmm 510 0.16 1.5e-18 -6.5 -6.4 1.6e-10 -0.70 0.99 0.01 FALSE
2 GTEx Brain Cerebellar Hemisphere DLD 0.24 0.06 enet 16 0.05 1.7e-02 5.7 -6.9 4.8e-12 -0.74 0.02 0.92 FALSE
3 GTEx Brain Frontal Cortex BA9 DLD 0.21 0.13 lasso 4 0.13 2.8e-04 -5.9 -6.4 2.1e-10 -0.53 0.04 0.81 FALSE
4 GTEx Brain Hypothalamus DLD 0.31 0.04 enet 10 0.04 4.6e-02 6.9 -7.4 2.0e-13 -0.88 0.09 0.69 FALSE
5 GTEx Testis DLD 0.11 0.12 lasso 2 0.06 1.1e-03 -6.5 -6.5 1.1e-10 -0.57 0.18 0.35 FALSE
6 NTR Blood DLD 0.04 0.02 lasso 2 0.02 2.2e-08 -6.5 -6.6 4.1e-11 -0.58 0.97 0.03 FALSE
7 ROSMAP Brain Pre-frontal Cortex LAMB1 0.06 0.05 enet 14 0.05 3.3e-07 -6.5 5.8 5.7e-09 0.40 0.97 0.02 FALSE
8 ROSMAP Brain Pre-frontal Cortex DLD 0.12 0.12 lasso 8 0.15 2.1e-18 7.0 -7.4 9.5e-14 -0.81 0.76 0.24 TRUE
9 YFS Blood DLD 0.02 0.01 bslmm 508 0.01 2.3e-04 -6.4 6.1 1.4e-09 0.62 0.45 0.54 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma DLD 0.05 0.04 blup 64 0.04 2.0e-04 7.5 -6.3 3.4e-10 -0.89 0.01 0.96 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma DLD 0.09 0.12 blup 64 0.11 2.5e-12 6.9 -6.7 1.6e-11 -0.88 0.28 0.72 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma LAMB1 0.03 0.01 blup 92 0.02 7.7e-03 1.2 -5.2 1.6e-07 -0.54 0.04 0.29 FALSE