[Hub]/) : Traits : Irritable Bowel Disease (IBD) :

chr9:4,287,179-6,472,714

Best TWAS P=2.45e-21 · Best GWAS P=3.14e-26 conditioned to 1.49e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 ROSMAP Brain Pre-frontal Cortex KIAA1432 0.05 0.00 blup 502 0.02 7.5e-04 1.8 5.7 9.9e-09 0.55 0.07 0.42 FALSE
2 ROSMAP Brain Pre-frontal Cortex IGHEP2 0.08 0.07 enet 12 0.08 3.7e-10 9.2 -9.5 2.5e-21 -0.93 1.00 0.00 TRUE
3 YFS Blood JAK2 0.03 0.03 lasso 4 0.03 1.4e-10 -5.7 7.8 6.4e-15 0.73 0.99 0.01 FALSE
4 The Cancer Genome Atlas Lung Adenocarcinoma JAK2 0.07 0.00 blup 83 0.02 2.2e-03 9.1 6.5 6.1e-11 0.71 0.03 0.08 FALSE