Best TWAS P=1.28e-24 · Best GWAS P=4.1e-27 conditioned to 0.00127
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | TNFSF15 | 0.05 | 0.06 | lasso | 3 | 0.06 | 5.4e-09 | -11 | -10 | 1.3e-24 | 0.82 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TNFSF15 | 0.02 | 0.01 | blup | 54 | 0.01 | 7.6e-03 | -11 | -10 | 1.9e-24 | 0.73 | 0.01 | 0.76 | TRUE |